Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	MATN1 COL5A3 FBN1 NID1 LTBP1 AGRN FBN3	8.24e-05	188	110	7	GO:0005201
GeneOntologyBiologicalProcess	transport across blood-brain barrier	SLCO3A1 SLC22A8 LRP2 SLC7A5 ATP1A2 ATP1A4	6.41e-06	87	108	6	GO:0150104
GeneOntologyBiologicalProcess	vascular transport	SLCO3A1 SLC22A8 LRP2 SLC7A5 ATP1A2 ATP1A4	6.85e-06	88	108	6	GO:0010232
GeneOntologyBiologicalProcess	organic anion transport	AVP SLCO3A1 SLC22A8 SLC35B4 SLC7A5P2 SLC22A10 LRP2 SLC7A5 SLC25A29 ATP1A2 SLC7A5P1 SLC4A9	1.64e-05	515	108	12	GO:0015711
GeneOntologyBiologicalProcess	vascular process in circulatory system	AVP SLCO3A1 FAAH SLC22A8 LRP2 SLC7A5 ATP1A2 ATP1A4 NOS3	8.26e-05	344	108	9	GO:0003018
GeneOntologyBiologicalProcess	sodium ion export across plasma membrane	ATP1A2 ATP1A4 AGRN	9.00e-05	17	108	3	GO:0036376
GeneOntologyBiologicalProcess	L-alpha-amino acid transmembrane transport	SLC7A5P2 SLC7A5 SLC25A29 ATP1A2 SLC7A5P1	9.42e-05	87	108	5	GO:1902475
GeneOntologyCellularComponent	basal plasma membrane	RHCG SLCO3A1 TF NOD2 VANGL2 SLC22A8 PLPP3 SLC22A10 SLC7A5 SLC4A9	1.79e-05	354	110	10	GO:0009925
GeneOntologyCellularComponent	basal part of cell	RHCG SLCO3A1 TF NOD2 VANGL2 SLC22A8 PLPP3 SLC22A10 SLC7A5 SLC4A9	3.13e-05	378	110	10	GO:0045178
GeneOntologyCellularComponent	microfibril	FBN1 LTBP1 FBN3	3.90e-05	13	110	3	GO:0001527
GeneOntologyCellularComponent	basolateral plasma membrane	RHCG SLCO3A1 NOD2 VANGL2 SLC22A8 PLPP3 SLC22A10 SLC7A5 SLC4A9	4.94e-05	320	110	9	GO:0016323
MousePheno	abnormal mast cell morphology	SELE LYST STAT6 FBN1 HDC	3.66e-06	42	79	5	MP:0000359
Domain	cEGF	FBN1 LRP2 NID1 LTBP1 FBN3	3.06e-07	26	105	5	IPR026823
Domain	cEGF	FBN1 LRP2 NID1 LTBP1 FBN3	3.06e-07	26	105	5	PF12662
Domain	EGF_CA	MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	4.32e-07	122	105	8	SM00179
Domain	EGF-like_Ca-bd_dom	MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	4.89e-07	124	105	8	IPR001881
Domain	EGF	SELE MATN1 DLK1 LRP2 NID1 LTBP1 AGRN FBN3	5.53e-07	126	105	8	PF00008
Domain	EGF_3	SELE CNTNAP3B MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	8.34e-07	235	105	10	PS50026
Domain	EGF	SELE CNTNAP3B MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	8.34e-07	235	105	10	SM00181
Domain	EGF-like_dom	SELE CNTNAP3B MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	1.41e-06	249	105	10	IPR000742
Domain	EGF_1	SELE CNTNAP3B MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	1.75e-06	255	105	10	PS00022
Domain	EGF_2	SELE CNTNAP3B MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	2.47e-06	265	105	10	PS01186
Domain	TB	FBN1 LTBP1 FBN3	5.94e-06	7	105	3	PF00683
Domain	EGF_CA	MATN1 FBN1 LRP2 NID1 LTBP1 FBN3	8.93e-06	86	105	6	PF07645
Domain	-	FBN1 LTBP1 FBN3	9.47e-06	8	105	3	3.90.290.10
Domain	TB	FBN1 LTBP1 FBN3	1.42e-05	9	105	3	PS51364
Domain	TB_dom	FBN1 LTBP1 FBN3	1.42e-05	9	105	3	IPR017878
Domain	EGF-like_CS	SELE MATN1 DLK1 FBN1 LRP2 NID1 LTBP1 AGRN FBN3	1.65e-05	261	105	9	IPR013032
Domain	ASX_HYDROXYL	DLK1 FBN1 LRP2 NID1 LTBP1 FBN3	2.12e-05	100	105	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	DLK1 FBN1 LRP2 NID1 LTBP1 FBN3	2.96e-05	106	105	6	IPR000152
Domain	FBN	FBN1 FBN3	9.36e-05	3	105	2	IPR011398
Domain	Crotonase_core_superfam	CDY1 CDYL CDY2A	1.11e-04	17	105	3	IPR001753
Domain	ECH_1	CDY1 CDYL CDY2A	1.11e-04	17	105	3	PF00378
Domain	EGF_Ca-bd_CS	FBN1 LRP2 NID1 LTBP1 FBN3	2.18e-04	97	105	5	IPR018097
Domain	EGF_CA	FBN1 LRP2 NID1 LTBP1 FBN3	2.40e-04	99	105	5	PS01187
Domain	Growth_fac_rcpt_	FBN1 ELAPOR1 LRP2 NID1 LTBP1 FBN3	2.51e-04	156	105	6	IPR009030
Domain	ZINC_FINGER_C2H2_2	ZNF133 ZNF678 ZNF689 ZNF835 RLF WIZ HELZ2 ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	4.03e-04	775	105	13	PS50157
Domain	Chromo	CDY1 CDYL CDY2A	4.09e-04	26	105	3	PF00385
Domain	ZINC_FINGER_C2H2_1	ZNF133 ZNF678 ZNF689 ZNF835 RLF WIZ HELZ2 ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	4.13e-04	777	105	13	PS00028
Domain	P-type_ATPase_IIC	ATP1A2 ATP1A4	4.63e-04	6	105	2	IPR005775
Domain	CHROMO_1	CDY1 CDYL CDY2A	5.11e-04	28	105	3	PS00598
Domain	CHROMO_2	CDY1 CDYL CDY2A	5.11e-04	28	105	3	PS50013
Domain	ZnF_C2H2	ZNF133 ZNF678 ZNF689 ZNF835 RLF WIZ HELZ2 ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	5.98e-04	808	105	13	SM00355
Domain	Chromodomain-like	CDY1 CDYL CDY2A	7.61e-04	32	105	3	IPR016197
Domain	Chromo/shadow_dom	CDY1 CDYL CDY2A	8.33e-04	33	105	3	IPR000953
Domain	CHROMO	CDY1 CDYL CDY2A	8.33e-04	33	105	3	SM00298
Domain	PENTAXIN	PTX3 ADGRD2	1.10e-03	9	105	2	PS00289
Domain	Chromo_dom_subgr	CDY1 CDY2A	1.37e-03	10	105	2	IPR017984
Domain	ConA-like_dom	CNTNAP3B COL5A3 RSPRY1 PTX3 ADGRD2 AGRN	1.49e-03	219	105	6	IPR013320
Domain	Pentaxin-related	PTX3 ADGRD2	1.67e-03	11	105	2	IPR001759
Domain	Pentaxin	PTX3 ADGRD2	1.67e-03	11	105	2	PF00354
Domain	Znf_C2H2-like	ZNF133 ZNF689 ZNF835 RLF WIZ HELZ2 ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	1.70e-03	796	105	12	IPR015880
Domain	zf-C2H2	ZNF133 ZNF678 ZNF689 ZNF835 RLF ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	1.78e-03	693	105	11	PF00096
Domain	Znf_C2H2	ZNF133 ZNF678 ZNF689 ZNF835 RLF WIZ ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	1.87e-03	805	105	12	IPR007087
Domain	LamG	CNTNAP3B COL5A3 AGRN	1.93e-03	44	105	3	SM00282
Domain	Ldl_recept_b	LRP2 NID1	2.73e-03	14	105	2	PF00058
Domain	LDLRB	LRP2 NID1	2.73e-03	14	105	2	PS51120
Domain	-	WDR27 EML2 WDR54 LYST WDR73 GNB3 SEMA3E	2.75e-03	333	105	7	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	WDR27 EML2 WDR54 LYST WDR73 GNB3 SEMA3E	2.85e-03	335	105	7	IPR015943
Domain	LY	LRP2 NID1	3.13e-03	15	105	2	SM00135
Domain	LDLR_classB_rpt	LRP2 NID1	3.13e-03	15	105	2	IPR000033
Domain	WD40	WDR27 EML2 WDR54 LYST WDR73 GNB3	3.44e-03	259	105	6	PF00400
Domain	-	ATP1A2 ATP1A4	3.57e-03	16	105	2	1.20.1110.10
Domain	ATPase_P-typ_TM_dom	ATP1A2 ATP1A4	3.57e-03	16	105	2	IPR023298
Domain	TY	TG NID1	4.03e-03	17	105	2	SM00211
Domain	ATPase_P-typ_cation-transptr_C	ATP1A2 ATP1A4	4.03e-03	17	105	2	IPR006068
Domain	-	TG NID1	4.03e-03	17	105	2	4.10.800.10
Domain	Cation_ATPase_C	ATP1A2 ATP1A4	4.03e-03	17	105	2	PF00689
Domain	THYROGLOBULIN_1_2	TG NID1	4.03e-03	17	105	2	PS51162
Domain	Thyroglobulin_1	TG NID1	4.03e-03	17	105	2	IPR000716
Domain	Thyroglobulin_1	TG NID1	4.03e-03	17	105	2	PF00086
Domain	THYROGLOBULIN_1_1	TG NID1	4.03e-03	17	105	2	PS00484
Domain	WD40	WDR27 EML2 WDR54 LYST WDR73 GNB3	4.07e-03	268	105	6	SM00320
Domain	Laminin_G	CNTNAP3B COL5A3 AGRN	4.26e-03	58	105	3	IPR001791
Domain	WD40_repeat	WDR27 EML2 WDR54 LYST WDR73 GNB3	4.37e-03	272	105	6	IPR001680
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	4.52e-03	18	105	2	PF00690
Domain	Cation_ATPase_N	ATP1A2 ATP1A4	4.52e-03	18	105	2	SM00831
Domain	WD_REPEATS_1	WDR27 EML2 WDR54 LYST WDR73 GNB3	4.85e-03	278	105	6	PS00678
Domain	-	ZNF133 ZNF689 ZNF835 RLF ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	4.89e-03	679	105	10	3.30.160.60
Domain	WD_REPEATS_2	WDR27 EML2 WDR54 LYST WDR73 GNB3	4.94e-03	279	105	6	PS50082
Domain	WD_REPEATS_REGION	WDR27 EML2 WDR54 LYST WDR73 GNB3	4.94e-03	279	105	6	PS50294
Domain	ATPase_P-typ_cation-transptr_N	ATP1A2 ATP1A4	5.03e-03	19	105	2	IPR004014
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	RHCG AVP SLCO3A1 SLC22A8 SLC35B4 SLC9A7 SLC7A5 SLC25A29 SLC4A9	4.08e-06	238	74	9	MM15076
Pathway	REACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT	RHCG AVP SLCO3A1 SLC22A8 SLC35B4 SLC9A7 SLC7A5 SLC25A29 SLC4A9	5.89e-06	249	74	9	M5988
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	RHCG AVP SLCO3A1 TF SLC22A8 SLC35B4 SLC9A7 SLC7A5 SLC25A29 ATP1A2 GNB3 ATP1A4 SLC4A9	4.77e-05	681	74	13	MM14985
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	RHCG AVP SLCO3A1 TF SLC22A8 SLC35B4 SLC9A7 SLC7A5 SLC25A29 ATP1A2 GNB3 ATP1A4 SLC4A9	1.05e-04	736	74	13	M27287
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	MATN1 ITGA10 COL5A3 FBN1 NID1 LTBP1 AGRN FBN3	1.71e-04	300	74	8	M610
Pathway	WP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE	FBN1 LTBP1 FBN3	2.94e-04	25	74	3	M39713
Pubmed	Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.	CDY1 CDYL CDY2A	3.06e-07	5	110	3	10192397
Pubmed	Characterization of 458 single nucleotide polymorphisms of disease candidate genes in the Korean population.	SELE DLK1 LRP2 HDC	6.63e-07	22	110	4	12768436
Pubmed	Up-regulated expression of a novel gene in activated human peripheral blood mononuclear cells that is a truncated paralog of the human system L-amino acid transporter 1.	SLC7A5P2 SLC7A5 SLC7A5P1	1.07e-06	7	110	3	12009310
Pubmed	Mammalian chromodomain proteins: their role in genome organisation and expression.	CDY1 CDYL CDY2A	1.70e-06	8	110	3	10655032
Pubmed	Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis.	CDY1 CDYL CDY2A	1.70e-06	8	110	3	12072557
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TBKBP1 MTMR8 EML2 ANKHD1 LYST NOD2 DIP2A WIZ NEK8 HELZ2 SLC7A5 DISP2 ZNF324B AGRN PKN3	2.17e-06	1105	110	15	35748872
Pubmed	Impact of genomic polymorphism on arterial hypertension after aortic coarctation repair.	FBN1 GNB3 NOS3	4.99e-06	11	110	3	20537417
Pubmed	Molecular physiology of renal organic anion transporters.	SLCO3A1 SLC22A8 SLC22A10	8.60e-06	13	110	3	16403838
Pubmed	Helminth infection promotes colonization resistance via type 2 immunity.	STAT6 NOD2	9.91e-06	2	110	2	27080105
Pubmed	Aggravated myocardial infarction-induced cardiac remodeling and heart failure in histamine-deficient mice.	STAT6 HDC	9.91e-06	2	110	2	28272448
Pubmed	Role of the eNOS Glu298Asp variant on the GNB3825T allele dependent determination of alpha-adrenergic coronary constriction.	GNB3 NOS3	9.91e-06	2	110	2	12724620
Pubmed	Effects of polymorphisms of NOS3 and GNB3 genes on skin microvascular reactivity in normal pregnancy.	GNB3 NOS3	9.91e-06	2	110	2	23667878
Pubmed	The N-Terminal Region of Fibrillin-1 Mediates a Bipartite Interaction with LTBP1.	FBN1 LTBP1	9.91e-06	2	110	2	28669633
Pubmed	G-protein beta-3-subunit and eNOS gene polymorphism in transplant recipients with long-term renal graft function.	GNB3 NOS3	9.91e-06	2	110	2	12424427
Pubmed	GNB3, eNOS, and mitochondrial DNA polymorphisms correlate to natural longevity in a Xinjiang Uygur population.	GNB3 NOS3	9.91e-06	2	110	2	24376503
Pubmed	Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas.	TF TG	9.91e-06	2	110	2	12819023
Pubmed	Comprehensive insight into functional interaction between GNB3 C825T and eNOS T-786C, G894T gene polymorphisms and association with susceptibility to diabetic erectile dysfunction.	GNB3 NOS3	9.91e-06	2	110	2	30101547
Pubmed	The potential value of Copeptin and Pentraxin3 for evaluating the severity of coronary stenosis in patients with coronary artery disease.	AVP PTX3	9.91e-06	2	110	2	33080253
Pubmed	Characterization of two splice variants of human organic anion transporting polypeptide 3A1 isolated from human brain.	AVP SLCO3A1	9.91e-06	2	110	2	16971491
Pubmed	Interaction of G-protein beta3 subunit and nitric oxide synthase gene polymorphisms on carotid artery intima-media thickness in young adults: the Bogalusa Heart Study.	GNB3 NOS3	9.91e-06	2	110	2	18551105
Pubmed	Insulin-mediated venodilation is impaired in young, healthy carriers of the 825T allele of the G-protein beta3 subunit gene (GNB3).	GNB3 NOS3	9.91e-06	2	110	2	15961981
Pubmed	Selective loss of basal but not receptor-stimulated relaxation by endothelial nitric oxide synthase after isolation of the mouse aorta.	FBN1 NOS3	9.91e-06	2	110	2	23022329
Pubmed	Complementation of the beige mutation in cultured cells by episomally replicating murine yeast artificial chromosomes.	LYST NID1	9.91e-06	2	110	2	8650191
Pubmed	Endothelium function biomarkers and carotid intima-media thickness changes in relation to NOS3 (rs2070744) and GNB3 (rs5443) genes polymorphism in the essential arterial hypertension.	GNB3 NOS3	9.91e-06	2	110	2	35489051
Pubmed	The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.	ATP1A2 ATP1A4	9.91e-06	2	110	2	10555956
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	9.91e-06	2	110	2	15221638
Pubmed	Pleiotropic activation of endothelial function by angiotensin II receptor blockers is crucial to their protective anti-vascular remodeling effects.	FBN1 NOS3	9.91e-06	2	110	2	35697767
Pubmed	Identification of the homologous beige and Chediak-Higashi syndrome genes.	LYST NID1	9.91e-06	2	110	2	8717042
Pubmed	Changed serum levels of CD62E+, angiotensin II and copeptin in patients with chronic insomnia disorder: a link between insomnia and stroke?	SELE AVP	9.91e-06	2	110	2	35294864
Pubmed	Megalin (gp330): a putative endocytic receptor for thyroglobulin (Tg).	TG LRP2	9.91e-06	2	110	2	9492085
Pubmed	Heterogeneity in hand veins responses to acetylcholine is not associated with polymorphisms in the G-protein beta3-subunit (C825T) and endothelial nitric oxide synthase (G894T) genes but with serum low density lipoprotein cholesterol.	GNB3 NOS3	9.91e-06	2	110	2	11434508
Pubmed	Identification of the murine beige gene by YAC complementation and positional cloning.	LYST NID1	9.91e-06	2	110	2	8673129
Pubmed	Association of single-nucleotide polymorphisms from 17 candidate genes with baseline symptom-limited exercise test duration and decrease in duration over 20 years: the Coronary Artery Risk Development in Young Adults (CARDIA) fitness study.	ATP1A2 GNB3 NOS3	2.03e-05	17	110	3	20952631
Pubmed	Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification.	VANGL2 ATP1A2 ATP1A4	2.03e-05	17	110	3	11709546
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	SLCO3A1 LRP2 SLC7A5 ATP1A2 ATP1A4	2.17e-05	105	110	5	30280653
Pubmed	Blood pressure response to potassium supplementation is associated with genetic variation in endothelin 1 and interactions with E selectin in rural Chinese.	SELE NOS3	2.97e-05	3	110	2	19996987
Pubmed	Histamine promotes the differentiation of macrophages from CD11b+ myeloid cells and formation of foam cells through a Stat6-dependent pathway.	STAT6 HDC	2.97e-05	3	110	2	28600950
Pubmed	A role for the Ankyrin repeat containing protein Ankrd17 in Nod1- and Nod2-mediated inflammatory responses.	NOD2 ANKRD17	2.97e-05	3	110	2	23711367
Pubmed	Nidogen/entactin (Nid) maps to the proximal end of mouse chromosome 13 linked to beige (bg) and identifies a new region of homology between mouse and human chromosomes.	LYST NID1	2.97e-05	3	110	2	1672300
Pubmed	CD4 positive T helper cells contribute to retinal ganglion cell death in mouse model of ischemia reperfusion injury.	LYST STAT6	2.97e-05	3	110	2	23792169
Pubmed	Genetic risk factors for erectile dysfunction and genetic determinants of drug response--on the way to improve drug safety?	GNB3 NOS3	2.97e-05	3	110	2	12825146
Pubmed	Genetic association study of the GNB3 C825T, the ACE I/D and the eNOS G894T polymorphisms and the risk to develop erectile dysfunction in a German ED population.	GNB3 NOS3	2.97e-05	3	110	2	20629643
Pubmed	Genetic variants, endothelial function, and risk of preeclampsia among American Indians.	GNB3 NOS3	2.97e-05	3	110	2	21174581
Pubmed	Inhibition of Marfan Syndrome Aortic Root Dilation by Losartan: Role of Angiotensin II Receptor Type 1-Independent Activation of Endothelial Function.	FBN1 NOS3	2.97e-05	3	110	2	29433732
Pubmed	A scanning electron microscopic investigation of genetic emphysema in tight-skin, pallid, and beige mice, three different C57 BL/6J mutants.	LYST FBN1	2.97e-05	3	110	2	8780155
Pubmed	Mask family proteins ANKHD1 and ANKRD17 regulate YAP nuclear import and stability.	ANKHD1 ANKRD17	2.97e-05	3	110	2	31661072
Pubmed	LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.	FBN1 LTBP1	2.97e-05	3	110	2	17293099
Pubmed	[Single nucleotide polymorphisms of the CYP11B2, GNB3 and NOS3 genes in various ethnic groups of arctic zone of yakutia suffering from arterial hypertension].	GNB3 NOS3	2.97e-05	3	110	2	30737933
Pubmed	Neutrophil lysosomal dysfunctions in mutant C57 Bl/6J mice: interstrain variations in content of lysosomal elastase, cathepsin G and their inhibitors.	LYST FBN1	2.97e-05	3	110	2	8166647
Pubmed	The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15).	DLK1 IFRD1	2.97e-05	3	110	2	37603466
Pubmed	The targeted inactivation of TRβ gene in thyroid follicular cells suggests a new mechanism of regulation of thyroid hormone production.	SLCO3A1 TG SLC7A5	3.37e-05	20	110	3	24265449
Pubmed	Comparative physical and transcript maps of approximately 1 Mb around loop-tail, a gene for severe neural tube defects on distal mouse chromosome 1 and human chromosome 1q22-q23.	VANGL2 ATP1A2 ATP1A4	4.54e-05	22	110	3	11401431
Pubmed	Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail.	VANGL2 ATP1A2 ATP1A4	4.54e-05	22	110	3	11431695
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	GAK HTATIP2 CPSF4 WIZ SLC7A5 WDR73 GNB3 PYCR3	5.83e-05	419	110	8	33001583
Pubmed	14-3-3ε mediates the cell fate decision-making pathways in response of hepatocellular carcinoma to Bleomycin-induced DNA damage.	HDAC6 IVNS1ABP LTBP1 KPNB1	5.87e-05	66	110	4	23472066
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN1 FBN3	5.92e-05	4	110	2	25034023
Pubmed	Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism.	ZBTB18 KPNB1	5.92e-05	4	110	2	35800763
Pubmed	Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.	ATP1A2 ATP1A4	5.92e-05	4	110	2	21849490
Pubmed	The inositol Inpp5k 5-phosphatase affects osmoregulation through the vasopressin-aquaporin 2 pathway in the collecting system.	AVP LRP2	5.92e-05	4	110	2	21938401
Pubmed	A role for T helper 2 cells in mediating skin fibrosis in tight-skin mice.	STAT6 FBN1	5.92e-05	4	110	2	10486156
Pubmed	Analysis of a large cluster of SLC22 transporter genes, including novel USTs, reveals species-specific amplification of subsets of family members.	SLC22A8 SLC22A10	5.92e-05	4	110	2	19417012
Pubmed	A high-lipid diet potentiates left ventricular dysfunction in nitric oxide synthase 3-deficient mice after chronic pressure overload.	NEK8 NOS3	5.92e-05	4	110	2	20554900
Pubmed	The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.	LYST NID1	5.92e-05	4	110	2	9070932
Pubmed	Identification and characterization of the cynomolgus monkey chromodomain gene cynCDY, an orthologue of the human CDY gene family.	CDY1 CDY2A	5.92e-05	4	110	2	12149400
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN1 LTBP1	5.92e-05	4	110	2	12429738
Pubmed	Gene fusion and overlapping reading frames in the mammalian genes for 4E-BP3 and MASK.	ANKHD1 ANKRD17	5.92e-05	4	110	2	14557257
Pubmed	Positional cloning of the Chediak-Higashi syndrome gene: genetic mapping of the beige locus on mouse chromosome 13.	LYST NID1	5.92e-05	4	110	2	8952226
Pubmed	MS/MS in silico subtraction-based proteomic profiling as an approach to facilitate disease gene discovery: application to lens development and cataract.	EML2 SLC7A5	5.92e-05	4	110	2	31797049
Pubmed	A long-range restriction map of deletion interval 6 of the human Y chromosome: a region frequently deleted in azoospermic males.	CDY1 CDY2A	5.92e-05	4	110	2	9806824
Pubmed	Polymorphisms in four candidate genes in young patients with essential hypertension.	GNB3 NOS3	5.92e-05	4	110	2	16497648
Pubmed	Agrin regulation of alpha3 sodium-potassium ATPase activity modulates cardiac myocyte contraction.	ATP1A2 AGRN	5.92e-05	4	110	2	19376779
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL5A3 FBN1 NID1 LTBP1 AGRN	7.22e-05	135	110	5	28675934
Pubmed	CAPS2 Deficiency Impairs the Release of the Social Peptide Oxytocin, as Well as Oxytocin-Associated Social Behavior.	AVP NOS3	9.85e-05	5	110	2	33846232
Pubmed	The renal glomerulus of mice lacking s-laminin/laminin beta 2: nephrosis despite molecular compensation by laminin beta 1.	NID1 AGRN	9.85e-05	5	110	2	7670489
Pubmed	Multiple genes encode the human Na+,K+-ATPase catalytic subunit.	ATP1A2 ATP1A4	9.85e-05	5	110	2	3035563
Pubmed	Markers of Islet Endothelial Dysfunction Occur in Male B6.BKS(D)-Leprdb/J Mice and May Contribute to Reduced Insulin Release.	SELE NOS3	9.85e-05	5	110	2	27870582
Pubmed	Lack of association between certain candidate gene polymorphisms and the metabolic syndrome.	UCP3 GNB3	9.85e-05	5	110	2	15978856
Pubmed	Physical mapping of the beige critical region on mouse chromosome 13.	LYST NID1	9.85e-05	5	110	2	8854868
Pubmed	Specificity of the chromodomain Y chromosome family of chromodomains for lysine-methylated ARK(S/T) motifs.	CDY1 CDYL	9.85e-05	5	110	2	18450745
Pubmed	POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.	FBN1 LTBP1	9.85e-05	5	110	2	34411563
Pubmed	Regulation of Tat acetylation and transactivation activity by the microtubule-associated deacetylase HDAC6.	HDAC6 HTATIP2	9.85e-05	5	110	2	21220424
Pubmed	Genetic risk factors for renal failure among north Indian ESRD patients.	GNB3 NOS3	9.85e-05	5	110	2	18242170
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	SELE ZNF678 MATN1 LYST OR10X1 FAAH VANGL2 RLF NID1 CAMTA1 ATP1A4 ZBTB18	1.06e-04	1031	110	12	16710414
Pubmed	Association of genetic variants with chronic kidney disease in individuals with different lipid profiles.	SELE FBN1 UCP3 GNB3 NOS3	1.26e-04	152	110	5	19578796
Pubmed	Genetic associations of brain structural networks in schizophrenia: a preliminary study.	SELE GNB3 NOS3	1.30e-04	31	110	3	20691427
Pubmed	UBE2O and USP7 co-regulate RECQL4 ubiquitinylation and homologous recombination-mediated DNA repair.	ZNF689 ANKHD1 SLC7A5 ZNF574 KPNB1	1.38e-04	155	110	5	34921745
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	FBN1 PTX3 NID1 LTBP1 AGRN SEMA3E	1.43e-04	248	110	6	24006456
Pubmed	Human POGZ modulates dissociation of HP1alpha from mitotic chromosome arms through Aurora B activation.	ZNF689 WIZ ZNF324 ZNF324B	1.44e-04	83	110	4	20562864
Pubmed	The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.	ATP1A2 ATP1A4	1.47e-04	6	110	2	3036582
Pubmed	Sex-specific effect of the alpha-adducin (G460W) and AGTR1 (A1166C) polymorphism on carotid intima-media thickness.	GNB3 NOS3	1.47e-04	6	110	2	19620885
Pubmed	The association between arterial stiffness and the angiotensin II type 1 receptor (A1166C) polymorphism is influenced by the use of cardiovascular medication.	GNB3 NOS3	1.47e-04	6	110	2	19145770
Pubmed	The influence of six cardiovascular polymorphisms on a first event of ischemic heart disease is modified by sex and age.	GNB3 NOS3	1.47e-04	6	110	2	19779330
Pubmed	Latent transforming growth factor beta-binding proteins and fibulins compete for fibrillin-1 and exhibit exquisite specificities in binding sites.	FBN1 LTBP1	1.47e-04	6	110	2	19349279
Pubmed	The contribution of six polymorphisms to cardiovascular risk in a Dutch high-risk primary care population: the HIPPOCRATES project.	GNB3 NOS3	1.47e-04	6	110	2	19242491
Pubmed	Inhibition of nuclear import by the proapoptotic protein CC3.	HTATIP2 KPNB1	1.47e-04	6	110	2	15282309
Pubmed	Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.	SLCO3A1 SLC7A5	1.47e-04	6	110	2	20679730
Pubmed	SNP-by-fitness and SNP-by-BMI interactions from seven candidate genes and incident hypertension after 20 years of follow-up: the CARDIA Fitness Study.	GNB3 NOS3	1.47e-04	6	110	2	20944660
Pubmed	BMP1 controls TGFbeta1 activation via cleavage of latent TGFbeta-binding protein.	FBN1 LTBP1	1.47e-04	6	110	2	17015622
Pubmed	The genomic basis of cerebral palsy: a HuGE systematic literature review.	SELE GNB3 NOS3	1.72e-04	34	110	3	19238444
Pubmed	Endothelial Cyp26b1 restrains murine heart valve growth during development.	LYST PLPP3 NID1 NOS3 PKN3	1.75e-04	163	110	5	35364055
Interaction	ZNF324B interactions	ZNF689 HELZ2 ZNF324 MCAT ZNF324B ZNF445	7.49e-06	89	106	6	int:ZNF324B
GeneFamily	Solute carriers	RHCG SLCO3A1 SLC22A8 SLC35B4 UCP3 SLC22A10 SLC9A7 SLC7A5 SLC25A29 SLC4A9	2.38e-06	395	69	10	752
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF133 ZNF678 ZNF689 ZNF835 RLF WIZ ZNF324 ZNF81 ZNF324B ZBTB18 ZNF574 ZNF445	1.55e-05	718	69	12	28
GeneFamily	ATPase Na+/K+ transporting subunits	ATP1A2 ATP1A4	2.98e-04	7	69	2	1208
GeneFamily	WD repeat domain containing	WDR27 EML2 WDR54 LYST WDR73 GNB3	4.88e-04	262	69	6	362
ToppCell	normal_Lung-B_lymphocytes-GrB-secreting_B_cells\|normal_Lung / Location, Cell class and cell subclass	AVP NEK8 SLC9A7 SLC7A5 CDYL ZBTB18 TOX2	3.45e-07	183	109	7	c930b957d16f9b0904b6c424acd914532e5cc137
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A3 DLK1 CPED1 FBN1 PLPP3 NID1 ATP1A2	4.77e-07	192	109	7	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A3 DLK1 CPED1 FBN1 PLPP3 NID1 ATP1A2	4.94e-07	193	109	7	051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell	NS-critical-d_0-4-Epithelial-FOXN4+\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HDAC6 POLD1 BEND3 FAAH ELAPOR1 PYCR3	4.18e-06	172	109	6	a00bb44d33658cb3a98accd6b60f3ce964c425b4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MATN1 FBXO43 NID1 TOX2 NOS3 PKN3	4.93e-06	177	109	6	73ba0f0b4b33f10e9f036d6d9befa48a1258e682
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CNTNAP3B GAK RPH3AL IVNS1ABP PLPP3 NOS3	5.43e-06	180	109	6	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	RPH3AL NPDC1 PLPP3 NID1 AGRN NOS3	5.78e-06	182	109	6	997d37ca2af661c92a56add888762724dfccc890
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLCO3A1 FBN1 PLPP3 PTX3 NID1 LTBP1	6.75e-06	187	109	6	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE ITGA10 NPDC1 ADH6 FBN1 NOS3	6.96e-06	188	109	6	524d1d928c9386acf20e53d31894107dd7290dc7
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE ITGA10 NPDC1 ADH6 FBN1 NOS3	6.96e-06	188	109	6	1b57995d70cf81212e8d46dfaf44dbaf9c7bc4d5
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE ITGA10 NPDC1 ADH6 FBN1 NOS3	6.96e-06	188	109	6	cd2d1f8e43c252dd8730a5758458ef63e7ffc836
ToppCell	5'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE ITGA10 NPDC1 ADH6 FBN1 NOS3	6.96e-06	188	109	6	f5a2f324f3f6c5078d57130392d3f1ba74f29094
ToppCell	5'-Airway_Nasal-Endothelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELE ITGA10 NPDC1 ADH6 FBN1 NOS3	6.96e-06	188	109	6	6c9d5e4014f807149328ff4eabd5e86dfe18094d
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPDC1 FBN1 LTBP1 TOX2 NOS3 PKN3	7.18e-06	189	109	6	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 CPED1 FBN1 PLPP3 PTX3 NID1	7.40e-06	190	109	6	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 CPED1 FBN1 PLPP3 PTX3 NID1	7.40e-06	190	109	6	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 CPED1 FBN1 PLPP3 PTX3 NID1	7.40e-06	190	109	6	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	droplet-Limb_Muscle\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 IFRD1 FBN1 PLPP3 PTX3 NID1	7.40e-06	190	109	6	06c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A3 CPED1 FBN1 PLPP3 NID1 ATP1A2	7.62e-06	191	109	6	9f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPDC1 FBN1 LTBP1 TOX2 NOS3 PKN3	7.62e-06	191	109	6	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	droplet-Limb_Muscle-nan-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PTX3 NID1 LTBP1	7.85e-06	192	109	6	2d9e2262f1342fe17735f21f733c029d1275e955
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NPDC1 FBN1 LTBP1 TOX2 NOS3 PKN3	8.09e-06	193	109	6	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	facs-Lung-nan-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 CPED1 FBN1 NID1 LTBP1 ATP1A2	8.09e-06	193	109	6	d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.33e-06	194	109	6	f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCell	facs-MAT-Fat-18m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.33e-06	194	109	6	944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.33e-06	194	109	6	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.33e-06	194	109	6	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.33e-06	194	109	6	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	facs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.33e-06	194	109	6	85081d255fcc1e9854c0073321dd9f0feaa48866
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPED1 FBN1 PLPP3 NID1 LTBP1 ATP1A2	8.58e-06	195	109	6	69a29d03e664b72f32d41876510c62345c3aed31
ToppCell	Endothelial-A-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	SELE NPDC1 PLPP3 SLC7A5 TOX2 NOS3	8.58e-06	195	109	6	c3a0aa34b672c99cb3a2a4e9218412dbd19da3ca
ToppCell	facs-GAT-Fat-3m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPED1 FBN1 PLPP3 NID1 LTBP1 ATP1A2	8.58e-06	195	109	6	1cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCell	facs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPED1 FBN1 PLPP3 NID1 LTBP1 ATP1A2	8.58e-06	195	109	6	9cef6f18664518060af7c192310dddce6d70345a
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPDC1 CPED1 FBN1 LRP2 NID1 LTBP1	8.83e-06	196	109	6	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.83e-06	196	109	6	65f2f51e17f1869f3468813127b96d3048d8ad41
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPDC1 CPED1 FBN1 LRP2 NID1 LTBP1	8.83e-06	196	109	6	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	facs-SCAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.83e-06	196	109	6	e4ed897900a6472738bc6be2fb4817192727225d
ToppCell	facs-SCAT-Fat-18m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 NPDC1 FBN1 PLPP3 NID1 LTBP1	8.83e-06	196	109	6	2cd83176f2e8a9e6fa3c08cb33928a61e5fc43b6
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-25\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FBN1 PLPP3 PTX3 NID1 LTBP1 SEMA3E	8.83e-06	196	109	6	ed6047b48b6a96baa6a90c7af784e7c34b32824d
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RHCG ITGA10 NID1 LTBP1 ATP1A2 TMEM255A	9.36e-06	198	109	6	637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 DLK1 FBN1 NID1 LTBP1 ATP1A2	9.36e-06	198	109	6	5e70246a9ce199cb2fb5379912b8ab59456219e4
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TBKBP1 RPH3AL ITGA10 NID1 SLC7A5 AGRN	9.63e-06	199	109	6	1295f34a350bf48987e2fad411aaac3630efd3f1
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPH3AL HTATIP2 NPDC1 TG CKLF	1.71e-05	130	109	5	c63f402d6ab71c2fcef12174b3139e55a727266c
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF689 COL5A3 ATP1A2 CTU1 TMEM255A	2.53e-05	141	109	5	dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HDAC6 WDR54 LYST FAAH HDC	4.23e-05	157	109	5	8c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HDAC6 WDR54 LYST FAAH HDC	4.23e-05	157	109	5	ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCell	PND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	HDAC6 WDR54 LYST FAAH HDC	4.23e-05	157	109	5	008f938a338f43c3251dcac574f1b4f689926c71
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_bronchial_vessel-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SELE NPDC1 SLC22A8 SLC22A10 SLC4A9	5.06e-05	163	109	5	ba7d02db0f0e2f9916ec8db52c067c87b6917c23
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA10 SLCO3A1 DLK1 LTBP1 TMEM255A	5.36e-05	165	109	5	b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL5A3 DLK1 SHISA9 FBN1 LTBP1	5.36e-05	165	109	5	4e13fccd32029e2879e85f8966e582a46c09e4aa
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGA10 SLCO3A1 DLK1 LTBP1 TMEM255A	5.36e-05	165	109	5	28f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZNF689 WIZ DISP2 TMEM255A PKN3	5.36e-05	165	109	5	62457b7b74c6eae42d91d65e7dc6df6bf8e061f7
ToppCell	Endothelial-endothelial_cell_of_bronchial_vessel\|World / Lineage, Cell type, age group and donor	SELE CNTNAP3B NPDC1 SLC22A8 TOX2	5.36e-05	165	109	5	84e553d699ac56df89a77248f7308b9133e1b683
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SELE NPDC1 DISP2 NOS3 PKN3	5.52e-05	166	109	5	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	367C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	AVP NEK8 SLC7A5 TOX2 NOS3	6.18e-05	170	109	5	fbb7019c6fba87326702b51f6819ea1af5f3a9b7
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF689 BEND3 ELAPOR1 GNB3 TOX2	6.35e-05	171	109	5	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF689 BEND3 ELAPOR1 GNB3 TOX2	6.35e-05	171	109	5	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 PLPP3 NID1 LTBP1 TMEM255A	6.53e-05	172	109	5	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	droplet-Kidney-nan-18m-Lymphocytic-plasma_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HTATIP2 CPED1 TG SLC7A5 TMEM95	6.89e-05	174	109	5	c92eec5a14ca5269673582dd115ead8516e64c3e
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ITGA10 FBN1 NID1 LTBP1 ATP1A2	7.08e-05	175	109	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MATN1 ITGA10 NPDC1 DLK1 LTBP1	7.28e-05	176	109	5	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	DLK1 SHISA9 LRP2 SLC9A7 ATP1A2	7.47e-05	177	109	5	59726bfd98f656fdcedf448a7e2e76a9bfad8285
ToppCell	Mid-temporal_gyrus_(MTG)\|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL5A3 SHISA9 SLC22A8 SLC22A10 ANKRD24	7.68e-05	178	109	5	ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CNTNAP3B SLC25A29 TOX2 NOS3 PKN3	7.88e-05	179	109	5	d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ITGA10 FBN1 NID1 LTBP1 ATP1A2	8.09e-05	180	109	5	01f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CNTNAP3B SHB VANGL2 DIP2A SEMA3E	8.30e-05	181	109	5	08f44323bf71b6004a921bbc969c954c75feeb66
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	ZNF689 TM7SF3 LYST IVNS1ABP SLC7A5P1	8.30e-05	181	109	5	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	droplet-Liver-Npc-21m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPDC1 PLPP3 NID1 ATP1A4 NOS3	8.52e-05	182	109	5	dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPDC1 PLPP3 NID1 ATP1A4 NOS3	8.52e-05	182	109	5	010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCell	droplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPDC1 PLPP3 NID1 ATP1A4 NOS3	8.52e-05	182	109	5	b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T\|lymph-node_spleen / Manually curated celltypes from each tissue	AVP TM7SF3 FAAH SLC9A7 EXOSC4	8.75e-05	183	109	5	6c55fd737ed31f5b1aa41dc4dba7240521c19022
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELE TBKBP1 VANGL2 WIZ SEMA3E	8.75e-05	183	109	5	b0b5a41f1a40f9c946d0dc8b67eaccdd9f9b73a5
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	COL5A3 DLK1 CPED1 FBN1 PLPP3	8.97e-05	184	109	5	01257e5c12e38b849fd3d9496c43ded666249ba5
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CPED1 FBN1 NID1 LTBP1 SEMA3E	9.20e-05	185	109	5	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FBN1 PLPP3 NID1 LTBP1 SEMA3E	9.20e-05	185	109	5	1ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	COL5A3 FBN1 PLPP3 NID1 LTBP1	9.44e-05	186	109	5	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	facs-Heart-LA-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHISA9 FBN1 NID1 LTBP1 ATP1A2	9.44e-05	186	109	5	ed0a91f47e77fe21d4c7678d0f2a7c5f97d63dda
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	CNTNAP3B NPDC1 TOX2 NOS3 PKN3	9.44e-05	186	109	5	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	facs-Trachea-nan-24m-Mesenchymal\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 PTX3 NID1 LTBP1	9.68e-05	187	109	5	71385068e3fd0bfa7822ae176113a49460c8636b
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL5A3 PLPP3 ATP1A2 FBN3 TMEM255A	9.68e-05	187	109	5	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A3 CPED1 NID1 LTBP1 ATP1A2	9.68e-05	187	109	5	ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCell	COVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	SELE CNTNAP3B ITGA10 NPDC1 NOS3	9.68e-05	187	109	5	2d20193a6cacdfa4877457c97b0077408942186c
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 PTX3 NID1 LTBP1	9.68e-05	187	109	5	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	Endothelial-A-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	SELE NPDC1 LTBP1 TOX2 NOS3	9.68e-05	187	109	5	fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL5A3 CPED1 NID1 LTBP1 ATP1A2	9.68e-05	187	109	5	530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCell	facs-Trachea-nan-24m-Mesenchymal-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 PTX3 NID1 LTBP1	9.68e-05	187	109	5	e891e571f6bb9433a0046215de6cabd89ed1effc
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL5A3 PLPP3 ATP1A2 FBN3 TMEM255A	9.68e-05	187	109	5	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	normal-na-Hematopoietic-progenitor_cell\|normal / PBMC cell types (v2) per disease, treatment status, and sex	AVP FBN1 SLC22A10 LRP2 HDC	9.93e-05	188	109	5	013162466a3334b6967c0cb670c8577d809b1396
ToppCell	droplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 LTBP1 ATP1A2 NOS3 PKN3	9.93e-05	188	109	5	ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	FBN1 NID1 SLC7A5 LTBP1 HDC	9.93e-05	188	109	5	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	normal-na-Hematopoietic-progenitor_cell-female\|normal / PBMC cell types (v2) per disease, treatment status, and sex	AVP FBN1 SLC22A10 LRP2 HDC	9.93e-05	188	109	5	be25371e6459504b5f0c9ece3a0fe8f80c7824ca
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL5A3 DLK1 FBN1 NID1 LTBP1	9.93e-05	188	109	5	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	Mesenchymal-chondrocyte\|World / Lineage, Cell type, age group and donor	MATN1 ITGA10 DLK1 FBN1 ATP1A2	9.93e-05	188	109	5	7b1e3f8a941eaa68e89c562129a92314642eec66
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-nan\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 DLK1 SHISA9 FBN1 NID1	1.02e-04	189	109	5	544d95df910f1b276995624509a7e41b219baca0
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF678 NPDC1 PLPP3 NOS3 PKN3	1.02e-04	189	109	5	e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCell	Endothelial-endothelial_cell_of_artery\|World / Lineage, Cell type, age group and donor	CNTNAP3B NPDC1 TOX2 NOS3 PKN3	1.02e-04	189	109	5	fdd89c71113ac99b7c800c6def8888e512ff1128
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Airway_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NPDC1 FBN1 PLPP3 LTBP1 SEMA3E	1.02e-04	189	109	5	4f9608b84d135268a17455661870c46ae8554a24
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 PTX3 NID1 LTBP1	1.02e-04	189	109	5	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	droplet-Mammary_Gland\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL5A3 IFRD1 FBN1 PTX3 NID1	1.02e-04	189	109	5	d159892c9c4eb78d747ae6b44267a88cf870d31a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NPDC1 FBN1 TOX2 NOS3 PKN3	1.02e-04	189	109	5	12b6f1c3bf526b90e112374bf937701f645c5780
Drug	losartan	SELE AVP ITGA10 FBN1 SLC22A8 SLC9A7 MCAT ATP1A2 GNB3 NOS3 PKN3	2.05e-06	378	109	11	CID000003961
Drug	trimethaphan	SELE AVP SLC9A7 ATP1A2 GNB3 NOS3	2.54e-06	81	109	6	CID000023576
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN3	3.90e-05	3	107	2	DOID:65 (implicated_via_orthology)
Disease	Cruveilhier-Baumgarten Syndrome	AVP NOS3	7.78e-05	4	107	2	C0010398
Disease	dehydroepiandrosterone sulphate measurement	RPH3AL TMEM225B CPSF4 CAMTA1	1.11e-04	68	107	4	EFO_0007001
Disease	Portal Hypertension	AVP NOS3	1.29e-04	5	107	2	C0020541
Disease	hypertension (biomarker_via_orthology)	HDAC6 AVP FBN1 UCP3 ATP1A2 NOS3	1.84e-04	227	107	6	DOID:10763 (biomarker_via_orthology)
Disease	familial hemiplegic migraine (implicated_via_orthology)	ATP1A2 ATP1A4	2.70e-04	7	107	2	DOID:0060178 (implicated_via_orthology)
Disease	Acute kidney injury	AVP TF LRP2 NOS3	5.09e-04	101	107	4	C2609414
Disease	Acute Kidney Insufficiency	AVP TF LRP2 NOS3	5.09e-04	101	107	4	C1565662
Disease	Kidney Failure, Acute	AVP TF LRP2 NOS3	5.09e-04	101	107	4	C0022660
Disease	Essential hypertension	GNB3 NOS3	5.75e-04	10	107	2	cv:C0085580
Disease	Essential hypertension, genetic	GNB3 NOS3	5.75e-04	10	107	2	cv:CN305331
Disease	HYPERTENSION, ESSENTIAL	GNB3 NOS3	5.75e-04	10	107	2	145500
Disease	autoimmune thyroiditis (is_implicated_in)	TG LRP2	8.40e-04	12	107	2	DOID:7188 (is_implicated_in)
Disease	nervous system disease (implicated_via_orthology)	ATP1A2 ATP1A4	8.40e-04	12	107	2	DOID:863 (implicated_via_orthology)
Disease	Essential Hypertension	GNB3 NOS3	8.40e-04	12	107	2	C0085580
Disease	Depressed mood	AVP PTX3	9.90e-04	13	107	2	C0344315
Disease	Spermatogenic Failure, Nonobstructive, Y-Linked	CDY1 CDY2A	1.51e-03	16	107	2	C1839071
Disease	Spermatogenic failure, Y-linked, 2	CDY1 CDY2A	1.51e-03	16	107	2	cv:C1839071
Disease	SPERMATOGENIC FAILURE, Y-LINKED, 2	CDY1 CDY2A	1.51e-03	16	107	2	415000
Disease	Coronary Arteriosclerosis	PLPP3 GNB3 NOS3	1.72e-03	65	107	3	C0010054
Disease	Coronary Artery Disease	PLPP3 GNB3 NOS3	1.72e-03	65	107	3	C1956346
Disease	essential hypertension (is_implicated_in)	GNB3 NOS3	1.92e-03	18	107	2	DOID:10825 (is_implicated_in)
Disease	Liver Cirrhosis, Experimental	RPH3AL NPDC1 IFRD1 FBN1 SLC22A8 NID1 LTBP1 NOS3 CKLF	2.05e-03	774	107	9	C0023893
Disease	portal hypertension (implicated_via_orthology)	AVP NOS3	2.14e-03	19	107	2	DOID:10762 (implicated_via_orthology)
Disease	glomerulonephritis (biomarker_via_orthology)	FBN1 LTBP1	2.37e-03	20	107	2	DOID:2921 (biomarker_via_orthology)
Disease	Fetal Growth Retardation	DLK1 NOS3	2.37e-03	20	107	2	C0015934
Disease	e-selectin measurement	SELE NPDC1	2.87e-03	22	107	2	EFO_0004575
Disease	epilepsy (implicated_via_orthology)	CDYL ATP1A2 ATP1A4 NOS3	2.98e-03	163	107	4	DOID:1826 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
CGTACEGLFISVAFK	VANGL2	141	Q9ULK5
ESFLGTAVAGAAFCL	SLC4A9	446	Q96Q91
LVLFSAAGSVFCCGL	CDY1	331	Q9Y6F8
KLVLFSAAGSVFCCG	CDY2A	331	Q9Y6F7
AQCASGTGALGSCFE	CAMTA1	1021	Q9Y6Y1
FCLAQGLFFLCGSST	nan	331	Q9N2K0
EAFTACGFVQDCGLL	CPED1	676	A4D0V7
CLISCGFSTGFGAAI	ADH6	171	P28332
TCGDAVCAFGAVCSA	AGRN	601	O00468
AAGGCLSCSEVLCSF	ANKRD24	156	Q8TF21
TALTLACCGGFLEVA	ANKRD17	536	O75179
VGSFHCACAGGFALD	FBN3	1006	Q75N90
GFSGNFCEIVANSCT	DLK1	161	P80370
CATAVGAAALFAAGV	DISP2	1061	A7MBM2
FGCACQATVGIDFLS	RAB41	56	Q5JT25
FSGDALSVAGCGSCL	HAGHL	131	Q6PII5
DVDFSRGCSACGFAA	BEND3	281	Q5T5X7
GTTGVCAFDCLSELG	HDC	246	P19113
FVCACSAGFVDGTAL	EXOSC4	156	Q9NPD3
VCGQLVASACTAGFF	OR10X1	156	Q8NGY0
FQEAFCVVSDLCATG	MATN1	216	P21941
AFQGHDVGFCCLGTT	HTATIP2	81	Q9BUP3
LFVCGGFDGSHAISC	IVNS1ABP	561	Q9Y6Y0
CTFEATGFSKDLGIC	MTMR8	641	Q96EF0
GCGVTRNFSSCSAVA	KRT85	11	P78386
CAVGDTTEAFFCLDN	CFAP65	256	Q6ZU64
IKGTECSFSCNAGEF	ELAPOR1	86	Q6UXG2
AVFTCAESCSLGTGY	PDCD2	316	Q16342
ACGVFSIVGALCYAE	SLC7A5P1	91	Q8MH63
VCGEAFCENVEGSFL	LTBP1	1296	Q14766
TQFTCECSIGFRGDG	NID1	691	P14543
VACGDFFTACLTDRG	NEK8	396	Q86SG6
ACGVFSIVGALCYAE	SLC7A5	91	Q01650
GSSCEFSCEQGFVLK	SELE	391	P16581
AICFFPNGEAICTGS	GNB3	231	P16520
ACGVFSIVGALCYAE	SLC7A5P2	91	Q9GIP4
GFICSCTAGFETNVF	LRP2	3986	P98164
AAFQAACETFCVGED	NOS3	701	P29474
FCVAGAAALSVASLC	NPDC1	191	Q9NQX5
CVAAAGFSVGEFAAL	MCAT	146	Q8IVS2
GLCSRTACGFDFCVL	FBXO43	656	Q4G163
GRAASAVAVCSFLCF	GAK	511	O14976
CFFSTNCVEGTARGI	ATP1A2	241	P50993
LLSAVGSVFCCGLDF	CDYL	391	Q9Y232
NTIGSFKCRCDSGFA	FBN1	1046	P35555
SGQALCGACFCAAFE	CTU1	21	Q7Z7A3
LCGVVSGGVVCFFSS	DDX11L8	696	A8MPP1
GLLTFGAFCNFCTEA	AWAT1	106	Q58HT5
GAFCNFCTEATGFSK	AWAT1	111	Q58HT5
EFLAGFGDCCSLSDN	LYST	291	Q99698
FLAGAAAGAIQCVIC	SLC25A29	96	Q8N8R3
ATCFGVCCFIATDDI	IFRD1	191	O00458
ACAAGLIGDLCTAFG	KPNB1	816	Q14974
ACGSSVFSSGICARV	ITGA10	131	O75578
SGAAVCEFFLKAACG	CPSF4	36	O95639
GVFDRAVCCVGFSKS	EML2	156	O95834
PGASGVALACCFVAA	FAAH	11	O00519
LGSCGVFLALTTDAC	DIP2A	446	Q14689
AACGFCFFNSVAVAA	HDAC6	616	Q9UBN7
VVGDAVALCSFGACG	HELZ2	911	Q9BYK8
GFLDGFSLCQLSCVS	FBXO30	626	Q8TB52
VFGKGCLSSSFSCLF	SLC22A8	416	Q8TCC7
CGSSAAIFPEGIFRC	ZNF689	21	C0HLU2
RAFGVTDEGFSVCCH	POLD1	126	P28340
SFRVFCNFTAGGETC	COL5A3	1571	P25940
TSGFTGCLSAVRFGC	CNTNAP3B	1161	Q96NU0
CKEGIGFGDRTSTFC	PKN3	706	Q6P5Z2
GCCVGGGFDETLAFS	PTX3	316	P26022
VLGFLGSSSVFCKDC	RPH3AL	101	Q9UNE2
AVGLVFAGCCSNVIF	SLC35B4	6	Q969S0
RAFSASSASGAAGCC	SHB	126	Q15464
SFESVRCTFCVDAGV	RSPRY1	346	Q96DX4
CGADGITYLSACFAG	SLCO3A1	486	Q9UIG8
LACISFFTGACAFLA	TMEM225B	111	P0DP42
IAAFCCAIVDGVFAA	TMEM255A	101	Q5JRV8
GCFLFGCAISQSFTD	PLPP3	131	O14495
ALACLGIGCSAATFS	SLC22A10	436	Q63ZE4
SSGDFIFCCGTCGFR	SHISA9	91	B4DS77
AAVGLSACVFCGFPA	WIZ	411	O95785
CDFCGAGFDTRAGLS	WIZ	771	O95785
LSGSGVAFVCAFSEA	PYCR3	176	Q53H96
LSFVGCGVSFCALTT	ADGRD2	661	Q7Z7M1
LACCGGFSEVADFLI	ANKHD1	511	Q8IWZ3
CFFSTNCVEGTARGI	ATP1A4	251	Q13733
GVFALVTAVCCLADG	CKLF	111	Q9UBR5
LGGVFLAAAQACVFC	TMEM95	6	Q3KNT9
FVSAFGAGFCATVVA	UCP3	221	P55916
LCIGVCAFEGANTST	ZNF678	6	Q5SXM1
PFVCALCGAAFSQGS	ZNF324	396	O75467
LFGSNVTDCSGNFCL	TF	626	P02787
FCSVGPTECAALAFV	NOD2	771	Q9HC29
AVCFDGTKFTCGFDG	RLF	946	Q13129
FLVGSDAFCCNLASA	STAT6	41	P42226
GFLCDCTVLVGDAQF	ZBTB18	21	Q99592
AGGAATQELFCSACD	ZNF574	301	Q6ZN55
SICCADELGCFVGTA	AVP	56	P01185
CSFAVGAGFLAFLSC	SYNGR4	66	O95473
INADFCVASVCVAFG	RHCG	126	Q9UBD6
FGTVNCGECGLSFSK	ZNF133	211	P52736
VGVSFKCSDCGRTFS	ZNF445	481	P59923
TEAVAGAFSRCLGFC	TOX2	6	Q96NM4
CSGCGKAFSFSSALI	ZNF835	476	Q9Y2P0
EFKFCVGVCSDGAAS	ZBED9	961	Q6R2W3
LTCGTGAFDPVCAFI	SEMA3E	131	O15041
FNCLCAGAFGALAAA	TMEM42	41	Q69YG0
IAFSPCGRFAACGAE	WDR27	761	A2RRH5
EACGFTGVVAVLFCG	SLC9A7	376	Q96T83
EVGTIRCASFCAGFP	TBKBP1	536	A7MCY6
DADPCCTGFGFLNVS	TG	2001	P01266
FAFCCASGRLGLVDT	WDR73	191	Q6P4I2
FECSECGKGFSLNSA	ZNF81	386	P51508
CGARFCDSSGNSFAV	WDR54	306	Q9H977
ACSFEAGEGSCASLG	TM7SF3	276	Q9NS93
PFVCALCGAAFSQGS	ZNF324B	396	Q6AW86