Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	RAF1 BRAF MAP3K15 MAP3K5	4.31e-06	27	82	4	GO:0004709
GeneOntologyMolecularFunction	inositol 1,4,5-trisphosphate-gated calcium channel activity	ITPR1 ITPR3	4.98e-05	3	82	2	GO:0005220
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH9 DNAH7 DNAH14	5.21e-05	18	82	3	GO:0008569
GeneOntologyMolecularFunction	tRNA (cytidine-3-)-methyltransferase activity	METTL2A METTL2B	9.94e-05	4	82	2	GO:0052735
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH9 DNAH7 DNAH14	2.03e-04	28	82	3	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH9 DNAH7 DNAH14	4.69e-04	37	82	3	GO:0045505
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF14 ZNF140 ZNF680 EGR1 ZNF732 ZNF335 ZNF521 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	5.03e-04	1244	82	14	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF14 ZNF140 ZNF680 EGR1 ZNF732 ZNF335 ZNF521 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	6.23e-04	1271	82	14	GO:0000987
GeneOntologyMolecularFunction	tRNA (cytidine) methyltransferase activity	METTL2A METTL2B	7.34e-04	10	82	2	GO:0016427
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZNF521 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	7.97e-04	1459	82	15	GO:0000977
GeneOntologyMolecularFunction	calcium channel regulator activity	REM1 RRAD ITPR1	1.42e-03	54	82	3	GO:0005246
GeneOntologyMolecularFunction	inositol 1,4,5 trisphosphate binding	ITPR1 ITPR3	1.47e-03	14	82	2	GO:0070679
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZBTB8B ZNF521 ZNF736 ZNF84 REST ZNF418 ZNF551 ZNF697	1.72e-03	1412	82	14	GO:0000981
Domain	Znf_C2H2-like	ZNF462 ZNF14 ZNF326 ZNF140 ZNF680 AKAP8 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	9.75e-11	796	80	20	IPR015880
Domain	Znf_C2H2	ZNF462 ZNF14 ZNF326 ZNF140 ZNF680 AKAP8 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	1.19e-10	805	80	20	IPR007087
Domain	ZnF_C2H2	ZNF462 ZNF14 ZNF326 ZNF140 ZNF680 AKAP8 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	1.27e-10	808	80	20	SM00355
Domain	-	ZNF462 ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	4.24e-10	679	80	18	3.30.160.60
Domain	zf-C2H2	ZNF462 ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	5.88e-10	693	80	18	PF00096
Domain	Znf_C2H2/integrase_DNA-bd	ZNF462 ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	6.02e-10	694	80	18	IPR013087
Domain	ZINC_FINGER_C2H2_2	ZNF462 ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	3.46e-09	775	80	18	PS50157
Domain	ZINC_FINGER_C2H2_1	ZNF462 ZNF14 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 REST ZNF418 ZNF835 ZNF551 ZNF697	3.60e-09	777	80	18	PS00028
Domain	zf-C2H2_6	ZNF14 ZNF140 ZNF680 ZNF560 ZNF732 ZNF521 ZNF576 ZNF736 ZNF84 ZNF418 ZNF551	9.51e-08	314	80	11	PF13912
Domain	KRAB	ZNF14 ZNF140 ZNF680 ZNF560 ZNF732 ZNF736 ZNF84 ZNF418 ZNF551	2.21e-05	358	80	9	PS50805
Domain	KRAB	ZNF14 ZNF140 ZNF680 ZNF560 ZNF732 ZNF736 ZNF84 ZNF418 ZNF551	2.21e-05	358	80	9	PF01352
Domain	Dynein_heavy_chain_D4_dom	DNAH9 DNAH7 DNAH14	2.66e-05	14	80	3	IPR024317
Domain	Dynein_HC_stalk	DNAH9 DNAH7 DNAH14	2.66e-05	14	80	3	IPR024743
Domain	MT	DNAH9 DNAH7 DNAH14	2.66e-05	14	80	3	PF12777
Domain	AAA_8	DNAH9 DNAH7 DNAH14	2.66e-05	14	80	3	PF12780
Domain	KRAB	ZNF14 ZNF140 ZNF680 ZNF560 ZNF732 ZNF736 ZNF84 ZNF418 ZNF551	2.80e-05	369	80	9	SM00349
Domain	KRAB	ZNF14 ZNF140 ZNF680 ZNF560 ZNF732 ZNF736 ZNF84 ZNF418 ZNF551	2.86e-05	370	80	9	IPR001909
Domain	DHC_fam	DNAH9 DNAH7 DNAH14	3.32e-05	15	80	3	IPR026983
Domain	Dynein_heavy_dom	DNAH9 DNAH7 DNAH14	3.32e-05	15	80	3	IPR004273
Domain	Dynein_heavy	DNAH9 DNAH7 DNAH14	3.32e-05	15	80	3	PF03028
Domain	InsP3_rcpt-bd	ITPR1 ITPR3	5.42e-05	3	80	2	IPR000493
Domain	AKAP95	ZNF326 AKAP8	5.42e-05	3	80	2	IPR007071
Domain	ZF_C2H2_AKAP95	ZNF326 AKAP8	5.42e-05	3	80	2	PS51799
Domain	AKAP95	ZNF326 AKAP8	5.42e-05	3	80	2	PF04988
Domain	DUF4071	MAP3K15 MAP3K5	5.42e-05	3	80	2	IPR025136
Domain	DUF4071	MAP3K15 MAP3K5	5.42e-05	3	80	2	PF13281
Domain	FBN	FBN1 FBN3	5.42e-05	3	80	2	IPR011398
Domain	Small_GTPase_GEM/REM/Rad	REM1 RRAD	1.08e-04	4	80	2	IPR017358
Domain	MeTrfase	METTL2A METTL2B	1.08e-04	4	80	2	IPR026113
Domain	Ephrin_rec_like	PCSK5 ELAPOR2 TG	1.63e-04	25	80	3	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	PCSK5 ELAPOR2 TG	1.63e-04	25	80	3	IPR011641
Domain	Methyltransf_12	METTL2A METTL2B	2.69e-04	6	80	2	PF08242
Domain	RIH_assoc	ITPR1 ITPR3	2.69e-04	6	80	2	PF08454
Domain	RIH_assoc-dom	ITPR1 ITPR3	2.69e-04	6	80	2	IPR013662
Domain	RIH_dom	ITPR1 ITPR3	2.69e-04	6	80	2	IPR000699
Domain	Ins145_P3_rcpt	ITPR1 ITPR3	2.69e-04	6	80	2	IPR014821
Domain	Ryanodine_recept-rel	ITPR1 ITPR3	2.69e-04	6	80	2	IPR015925
Domain	-	ITPR1 ITPR3	2.69e-04	6	80	2	1.25.10.30
Domain	RYDR_ITPR	ITPR1 ITPR3	2.69e-04	6	80	2	PF01365
Domain	RBD	RAF1 BRAF	2.69e-04	6	80	2	PF02196
Domain	Ins145_P3_rec	ITPR1 ITPR3	2.69e-04	6	80	2	PF08709
Domain	Methyltransf_12	METTL2A METTL2B	2.69e-04	6	80	2	IPR013217
Domain	RBD	RAF1 BRAF	3.75e-04	7	80	2	SM00455
Domain	TB	FBN1 FBN3	3.75e-04	7	80	2	PF00683
Domain	RBD_dom	RAF1 BRAF	3.75e-04	7	80	2	IPR003116
Domain	RBD	RAF1 BRAF	3.75e-04	7	80	2	PS50898
Domain	-	FBN1 FBN3	4.99e-04	8	80	2	3.90.290.10
Domain	TB	FBN1 FBN3	6.40e-04	9	80	2	PS51364
Domain	TB_dom	FBN1 FBN3	6.40e-04	9	80	2	IPR017878
Domain	MIR	ITPR1 ITPR3	7.97e-04	10	80	2	PS50919
Domain	MIR	ITPR1 ITPR3	7.97e-04	10	80	2	PF02815
Domain	MIR	ITPR1 ITPR3	7.97e-04	10	80	2	SM00472
Domain	MIR_motif	ITPR1 ITPR3	7.97e-04	10	80	2	IPR016093
Domain	Dynein_heavy_dom-2	DNAH9 DNAH7	1.59e-03	14	80	2	IPR013602
Domain	DHC_N2	DNAH9 DNAH7	1.59e-03	14	80	2	PF08393
Domain	DAG/PE-bd	RAF1 BRAF	3.61e-03	21	80	2	IPR020454
Domain	SRCR	MSR1 SCARA5	3.61e-03	21	80	2	PF00530
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY	ITPR1 ITPR3	1.83e-04	5	61	2	M49000
Pathway	KEGG_LONG_TERM_DEPRESSION	RAF1 BRAF ITPR1 ITPR3	2.35e-04	70	61	4	M8232
Pathway	KEGG_LONG_TERM_POTENTIATION	RAF1 BRAF ITPR1 ITPR3	2.35e-04	70	61	4	M3115
Pathway	WP_PILOCYTIC_ASTROCYTOMA	RAF1 BRAF	2.73e-04	6	61	2	M39584
Pathway	REACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY	RAF1 BRAF	2.73e-04	6	61	2	M27559
Pathway	REACTOME_NEGATIVE_FEEDBACK_REGULATION_OF_MAPK_PATHWAY	RAF1 BRAF	2.73e-04	6	61	2	MM15273
Pathway	KEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR3	2.73e-04	6	61	2	M47960
Pathway	REACTOME_SIGNALING_BY_NTRKS	PCSK5 BRAF EGR1 REST RRAD	2.80e-04	134	61	5	M3574
Pathway	WP_REGUCALCIN_IN_PROXIMAL_TUBULE_EPITHELIAL_KIDNEY_CELLS	RAF1 BRAF MAP3K5	3.50e-04	32	61	3	M39893
Pathway	PID_MAPK_TRK_PATHWAY	RAF1 BRAF EGR1	4.19e-04	34	61	3	M270
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	PCSK5 BRAF EGR1 FGF2 REST RRAD DNMT1 ITPR1 ITPR3	4.37e-04	532	61	9	M27870
Pathway	KEGG_MEDICUS_REFERENCE_FGF_FGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF FGF2	4.57e-04	35	61	3	M47379
Pathway	REACTOME_SIGNALING_BY_MRAS_COMPLEX_MUTANTS	RAF1 BRAF	5.07e-04	8	61	2	M38999
Pathway	KEGG_MEDICUS_REFERENCE_REGULATION_OF_GF_RTK_RAS_ERK_SIGNALING_MRAS_SHOC2_PP1_HOLOPHOSPHATASE	RAF1 BRAF	5.07e-04	8	61	2	M47933
Pathway	REACTOME_NGF_STIMULATED_TRANSCRIPTION	EGR1 REST RRAD	6.31e-04	39	61	3	M29793
Pathway	KEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR3	6.50e-04	9	61	2	M47852
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	RAF1 BRAF PAQR3	7.85e-04	42	61	3	MM15274
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KRAS_NRAS_TO_ERK_SIGNALING_PATHWAY	RAF1 BRAF	8.11e-04	10	61	2	M47374
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR3	8.11e-04	10	61	2	M47661
Pathway	KEGG_MEDICUS_VARIANT_HRAS_OVEREXPRESSION_TO_ERK_SIGNALING_PATHWAY	RAF1 BRAF	8.11e-04	10	61	2	M47420
Pathway	KEGG_MEDICUS_REFERENCE_RAC_CDC42_PAK_ERK_SIGNALING_PATHWAY	RAF1 BRAF	8.11e-04	10	61	2	M47735
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	RAF1 BRAF PAQR3	8.41e-04	43	61	3	M27560
Pathway	KEGG_MEDICUS_VARIANT_RET_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	9.88e-04	11	61	2	M47370
Pathway	KEGG_MEDICUS_VARIANT_TRK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	9.88e-04	11	61	2	M47371
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR3	9.88e-04	11	61	2	M49033
Pathway	REACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION	ITPR1 ITPR3	9.88e-04	11	61	2	M27466
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	FGF2 REST OPRK1	1.03e-03	46	61	3	MM15949
Pathway	SIG_BCR_SIGNALING_PATHWAY	RAF1 ITPR1 ITPR3	1.03e-03	46	61	3	M8626
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.18e-03	12	61	2	M47369
Pathway	KEGG_MEDICUS_PATHOGEN_HBV_LHBS_TO_PKC_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.18e-03	12	61	2	M47597
Pathway	KEGG_MEDICUS_ENV_FACTOR_METALS_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.18e-03	12	61	2	M47815
Pathway	KEGG_MEDICUS_PATHOGEN_HCV_CORE_TO_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.39e-03	13	61	2	M47589
Pathway	BIOCARTA_CDK5_PATHWAY	RAF1 EGR1	1.39e-03	13	61	2	M89
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR1 ITPR3	1.39e-03	13	61	2	M47656
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	1.39e-03	13	61	2	M47696
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	1.39e-03	13	61	2	M47751
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	ITPR1 ITPR3	1.39e-03	13	61	2	MM14553
Pathway	KEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION	RAF1 BRAF ITPR1 ITPR3	1.53e-03	115	61	4	M9387
Pathway	KEGG_MEDICUS_VARIANT_BCR_ABL_FUSION_KINASE_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47364
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_KIT_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47365
Pathway	KEGG_MEDICUS_VARIANT_DUPLICATION_OR_MUTATION_ACTIVATED_FLT3_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47366
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_PDGFR_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47378
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_PLCG_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47383
Pathway	KEGG_MEDICUS_VARIANT_EML4_ALK_FUSION_KINASE_TO_PLCG_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47384
Pathway	BIOCARTA_CDK5_PATHWAY	RAF1 EGR1	1.62e-03	14	61	2	MM1457
Pathway	PID_TCR_RAS_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M134
Pathway	KEGG_MEDICUS_VARIANT_MET_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.62e-03	14	61	2	M47488
Pathway	KEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY	FGF2 ITPR1 ITPR3	1.72e-03	55	61	3	M47952
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_MET_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47367
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_EGFR_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47375
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_PLCG_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47382
Pathway	KEGG_MEDICUS_VARIANT_AMPLIFIED_FGFR_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47380
Pathway	KEGG_MEDICUS_REFERENCE_CA2_PYK2_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47592
Pathway	KEGG_MEDICUS_PATHOGEN_HBV_HBX_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47593
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_FGF17_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47640
Pathway	KEGG_MEDICUS_VARIANT_IGF2_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47485
Pathway	KEGG_MEDICUS_REFERENCE_HGF_MET_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47473
Pathway	KEGG_MEDICUS_REFERENCE_FLT3LG_FLT3_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47474
Pathway	KEGG_MEDICUS_REFERENCE_TGFA_EGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47480
Pathway	KEGG_MEDICUS_VARIANT_EGF_OVEREXPRESSION_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47495
Pathway	KEGG_MEDICUS_REFERENCE_EREG_EGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47496
Pathway	KEGG_MEDICUS_REFERENCE_AREG_EGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47497
Pathway	KEGG_MEDICUS_REFERENCE_KITLG_KIT_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47472
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_GB_TO_PDGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47535
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_EGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	1.87e-03	15	61	2	M47531
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	RYBP ZNF14 ZNF140 ZNF680 ZNF560 ZNF732 CASP1 ZNF521 ZNF736 REST ZNF418 ZNF551 OPRK1 ZNF697	2.01e-03	1387	61	14	M734
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47363
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_FGFR3_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47373
Pathway	KEGG_MEDICUS_REFERENCE_EGF_ERBB2_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47381
Pathway	KEGG_MEDICUS_REFERENCE_P4_PR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47804
Pathway	KEGG_MEDICUS_ENV_FACTOR_E2_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47801
Pathway	REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS	ITPR1 ITPR3	2.13e-03	16	61	2	M26945
Pathway	WP_MAPK_PATHWAY_IN_CONGENITAL_THYROID_CANCER	RAF1 BRAF	2.13e-03	16	61	2	M39882
Pathway	KEGG_MEDICUS_REFERENCE_IGF_IGF1R_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47483
Pathway	KEGG_MEDICUS_REFERENCE_AGE_RAGE_SIGNALING_PATHWAY	RAF1 BRAF	2.13e-03	16	61	2	M47682
Pathway	REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION	EGR1 REST RRAD	2.32e-03	61	61	3	M152
Pathway	KEGG_MEDICUS_REFERENCE_PDGF_PDGFR_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	2.40e-03	17	61	2	M47376
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_AGE_RAGE_SIGNALING_PATHWAY	RAF1 BRAF	2.40e-03	17	61	2	M47684
Pathway	WP_DYRK1A_INVOLVEMENT_REGARDING_CELL_PROLIFERATION_IN_BRAIN_DEVELOPMENT	FGF2 REST LIN9	2.43e-03	62	61	3	M45532
Pathway	WP_ENDOMETRIAL_CANCER	RAF1 BRAF FGF2	2.55e-03	63	61	3	M39623
Pathway	WP_INHIBITION_OF_EXOSOME_BIOGENESIS_AND_SECRETION_BY_MANUMYCIN_A_IN_CRPC_CELLS	RAF1 BRAF	2.70e-03	18	61	2	M39737
Pathway	PID_CD8_TCR_DOWNSTREAM_PATHWAY	RAF1 BRAF EGR1	2.78e-03	65	61	3	M272
Pathway	WP_THYROID_STIMULATING_HORMONE_TSH_SIGNALING	RAF1 BRAF EGR1	2.91e-03	66	61	3	M39684
Pathway	WP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING	BRAF EGR1	3.00e-03	19	61	2	M39358
Pathway	KEGG_MEDICUS_REFERENCE_CXCL12_CXCR4_PKC_ERK_SIGNALING_PATHAWAY	RAF1 BRAF	3.00e-03	19	61	2	M47596
Pathway	KEGG_MEDICUS_ENV_FACTOR_NNK_NNN_TO_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	3.00e-03	19	61	2	M47793
Pathway	REACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION	ITPR1 ITPR3	3.00e-03	19	61	2	M27423
Pathway	REACTOME_SCAVENGING_BY_CLASS_A_RECEPTORS	MSR1 SCARA5	3.00e-03	19	61	2	M27221
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	3.00e-03	19	61	2	M47760
Pathway	KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY	ITPR1 ITPR3	3.00e-03	19	61	2	M47733
Pathway	WP_SEROTONIN_RECEPTOR_2_AND_ELKSRFGATA4_SIGNALING	RAF1 ITPR1	3.33e-03	20	61	2	M39485
Pathway	KEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	3.33e-03	20	61	2	M47688
Pathway	KEGG_MELANOMA	RAF1 BRAF FGF2	3.58e-03	71	61	3	M15798
Pathway	KEGG_MEDICUS_REFERENCE_ACH_CHRN_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	3.67e-03	21	61	2	M47792
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	3.67e-03	21	61	2	M47689
Pathway	WP_MECP2_AND_ASSOCIATED_RETT_SYNDROME	FGF2 REST OPRK1	3.87e-03	73	61	3	M39401
Pathway	WP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY	CAPN3 ITPR1 ITPR3	4.02e-03	74	61	3	M48080
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	4.02e-03	22	61	2	M47690
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR1 ITPR3	4.02e-03	22	61	2	M47675
Pathway	KEGG_MEDICUS_REFERENCE_E2_ER_RAS_ERK_SIGNALING_PATHWAY	RAF1 BRAF	4.40e-03	23	61	2	M47799
Pubmed	In vivo functions of mitogen-activated protein kinases: conclusions from knock-in and knock-out mice.	RAF1 BRAF MAP3K5	1.26e-07	5	82	3	17219248
Pubmed	Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development.	RAF1 BRAF TG	1.50e-06	10	82	3	18952847
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	PCSK5 RAF1 FREM2 MARF1 PYGB PATJ RASAL2 DNMT1 ITPR1 FANCA	3.10e-06	650	82	10	38777146
Pubmed	Targets of Raf in tumorigenesis.	RAF1 BRAF	5.49e-06	2	82	2	20047953
Pubmed	Elimination of B-RAF in oncogenic C-RAF-expressing alveolar epithelial type II cells reduces MAPK signal intensity and lung tumor growth.	RAF1 BRAF	5.49e-06	2	82	2	25096573
Pubmed	Increased BRAF heterodimerization is the common pathogenic mechanism for noonan syndrome-associated RAF1 mutants.	RAF1 BRAF	5.49e-06	2	82	2	22826437
Pubmed	The Pro335 --> Leu polymorphism of type 3 inositol 1,4,5-trisphosphate receptor found in mouse inbred lines results in functional change.	ITPR1 ITPR3	5.49e-06	2	82	2	15890645
Pubmed	In melanoma, RAS mutations are accompanied by switching signaling from BRAF to CRAF and disrupted cyclic AMP signaling.	RAF1 BRAF	5.49e-06	2	82	2	17018604
Pubmed	Glucocorticoids delay RAF-induced senescence promoted by EGR1.	BRAF EGR1	5.49e-06	2	82	2	31371485
Pubmed	Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF.	RAF1 BRAF	5.49e-06	2	82	2	15035987
Pubmed	B-Raf and Raf-1 are regulated by distinct autoregulatory mechanisms.	RAF1 BRAF	5.49e-06	2	82	2	15710605
Pubmed	BRAF splice variants in rheumatoid arthritis synovial fibroblasts activate MAPK through CRAF.	RAF1 BRAF	5.49e-06	2	82	2	23517740
Pubmed	Transcription factor Egr-1 supports FGF-dependent angiogenesis during neovascularization and tumor growth.	EGR1 FGF2	5.49e-06	2	82	2	12872165
Pubmed	Raf-1 promotes cell survival by antagonizing apoptosis signal-regulating kinase 1 through a MEK-ERK independent mechanism.	RAF1 MAP3K5	5.49e-06	2	82	2	11427728
Pubmed	Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells.	RAF1 BRAF	5.49e-06	2	82	2	25473895
Pubmed	Raf kinases in cancer-roles and therapeutic opportunities.	RAF1 BRAF	5.49e-06	2	82	2	21577205
Pubmed	Essential, non-redundant roles of B-Raf and Raf-1 in Ras-driven skin tumorigenesis.	RAF1 BRAF	5.49e-06	2	82	2	22733131
Pubmed	Heteroligomers of type-I and type-III inositol trisphosphate receptors in WB rat liver epithelial cells.	ITPR1 ITPR3	5.49e-06	2	82	2	7559486
Pubmed	Fibroblast growth factor 2 and the transcription factor Egr-1 localise to endothelial cell microvascular channels in human coronary artery occlusion.	EGR1 FGF2	5.49e-06	2	82	2	15875316
Pubmed	Structural studies of inositol 1,4,5-trisphosphate receptor: coupling ligand binding to channel gating.	ITPR1 ITPR3	5.49e-06	2	82	2	20843799
Pubmed	CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations.	RAF1 BRAF	5.49e-06	2	82	2	18794803
Pubmed	Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis.	RAF1 MAP3K5	5.49e-06	2	82	2	15467832
Pubmed	Mutational analysis of the ligand binding site of the inositol 1,4,5-trisphosphate receptor.	ITPR1 ITPR3	5.49e-06	2	82	2	8663526
Pubmed	B-Raf and C-Raf are required for melanocyte stem cell self-maintenance.	RAF1 BRAF	5.49e-06	2	82	2	23022482
Pubmed	Identification of frequent BRAF copy number gain and alterations of RAF genes in Chinese prostate cancer.	RAF1 BRAF	5.49e-06	2	82	2	22833462
Pubmed	Rafs constitute a nodal point in the regulation of embryonic endothelial progenitor cell growth and differentiation.	RAF1 BRAF	5.49e-06	2	82	2	18205709
Pubmed	Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.	FBN1 FBN3	5.49e-06	2	82	2	15221638
Pubmed	Three additional inositol 1,4,5-trisphosphate receptors: molecular cloning and differential localization in brain and peripheral tissues.	ITPR1 ITPR3	5.49e-06	2	82	2	1374893
Pubmed	Epidermal RAF prevents allergic skin disease.	RAF1 BRAF	5.49e-06	2	82	2	27431613
Pubmed	RAF inhibitors activate the MAPK pathway by relieving inhibitory autophosphorylation.	RAF1 BRAF	5.49e-06	2	82	2	23680146
Pubmed	ERK MAP kinase signaling in post-mortem brain of suicide subjects: differential regulation of upstream Raf kinases Raf-1 and B-Raf.	RAF1 BRAF	5.49e-06	2	82	2	16172610
Pubmed	BRAF inactivation drives aneuploidy by deregulating CRAF.	RAF1 BRAF	5.49e-06	2	82	2	20978199
Pubmed	Active Ras induces heterodimerization of cRaf and BRaf.	RAF1 BRAF	5.49e-06	2	82	2	11325826
Pubmed	Tyr-167/Trp-168 in type 1/3 inositol 1,4,5-trisphosphate receptor mediates functional coupling between ligand binding and channel opening.	ITPR1 ITPR3	5.49e-06	2	82	2	20813840
Pubmed	Associations of the BRAF V600E Mutation and PAQR3 Protein Expression with Papillary Thyroid Carcinoma Clinicopathological Features.	BRAF PAQR3	5.49e-06	2	82	2	31758408
Pubmed	RAF inhibitors that evade paradoxical MAPK pathway activation.	RAF1 BRAF	5.49e-06	2	82	2	26466569
Pubmed	Griffipavixanthone, a dimeric xanthone extracted from edible plants, inhibits tumor metastasis and proliferation via downregulation of the RAF pathway in esophageal cancer.	RAF1 BRAF	5.49e-06	2	82	2	26646323
Pubmed	Wild-type and mutant B-RAF activate C-RAF through distinct mechanisms involving heterodimerization.	RAF1 BRAF	5.49e-06	2	82	2	16364920
Pubmed	Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.	ITPR1 ITPR3	5.49e-06	2	82	2	14707143
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	USP53 RAF1 ZNF326 AKAP8 BRAF BOLA2 PATJ LYST DNAH7 RASAL2 DNMT1	5.68e-06	861	82	11	36931259
Pubmed	Cross-talk between EphA2 and BRaf/CRaf is a key determinant of response to Dasatinib.	RAF1 BRAF	1.64e-05	3	82	2	24486585
Pubmed	Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.	ITPR1 ITPR3	1.64e-05	3	82	2	10874040
Pubmed	RAF inhibitors prime wild-type RAF to activate the MAPK pathway and enhance growth.	RAF1 BRAF	1.64e-05	3	82	2	20130576
Pubmed	Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.	ITPR1 ITPR3	1.64e-05	3	82	2	20395455
Pubmed	The strength of interaction at the Raf cysteine-rich domain is a critical determinant of response of Raf to Ras family small GTPases.	RAF1 BRAF	1.64e-05	3	82	2	10454553
Pubmed	Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.	ITPR1 ITPR3	1.64e-05	3	82	2	17437169
Pubmed	Mutation analysis of the BRAF, ARAF and RAF-1 genes in human colorectal adenocarcinomas.	RAF1 BRAF	1.64e-05	3	82	2	14688025
Pubmed	Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling.	RAF1 BRAF	1.64e-05	3	82	2	22510884
Pubmed	RGK protein-mediated impairment of slow depolarization- dependent Ca2+ entry into developing myotubes.	REM1 RRAD	1.64e-05	3	82	2	24476902
Pubmed	Expression of raf family proto-oncogenes in normal mouse tissues.	RAF1 BRAF	1.64e-05	3	82	2	1690378
Pubmed	MiR-203 regulates keloid fibroblast proliferation, invasion, and extracellular matrix expression by targeting EGR1 and FGF2.	EGR1 FGF2	1.64e-05	3	82	2	30372829
Pubmed	Endothelial apoptosis in Braf-deficient mice.	RAF1 BRAF	1.64e-05	3	82	2	9207797
Pubmed	Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.	ITPR1 ITPR3	1.64e-05	3	82	2	18547250
Pubmed	Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.	ITPR1 ITPR3	1.64e-05	3	82	2	36350267
Pubmed	The versatility and universality of calcium signalling.	ITPR1 ITPR3	1.64e-05	3	82	2	11413485
Pubmed	B- and C-RAF display essential differences in their binding to Ras: the isotype-specific N terminus of B-RAF facilitates Ras binding.	RAF1 BRAF	1.64e-05	3	82	2	17635919
Pubmed	Effects of Raf dimerization and its inhibition on normal and disease-associated Raf signaling.	RAF1 BRAF	1.64e-05	3	82	2	23352452
Pubmed	Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR3	1.64e-05	3	82	2	26009177
Pubmed	Active caspase-1 is a regulator of unconventional protein secretion.	CASP1 FGF2	1.64e-05	3	82	2	18329368
Pubmed	Apoptosis-linked gene-2 connects the Raf-1 and ASK1 signalings.	RAF1 MAP3K5	1.64e-05	3	82	2	15925322
Pubmed	Receptor-activated single channels in intact human platelets.	ITPR1 ITPR3	1.64e-05	3	82	2	1693919
Pubmed	Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF.	RAF1 BRAF	1.64e-05	3	82	2	20141835
Pubmed	ERK and PDE4 cooperate to induce RAF isoform switching in melanoma.	RAF1 BRAF	1.64e-05	3	82	2	21478863
Pubmed	Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.	ITPR1 ITPR3	1.64e-05	3	82	2	23955339
Pubmed	Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.	ITPR1 ITPR3	1.64e-05	3	82	2	31979185
Pubmed	Overlapping and specific functions of Braf and Craf-1 proto-oncogenes during mouse embryogenesis.	RAF1 BRAF	1.64e-05	3	82	2	10704835
Pubmed	Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.	ITPR1 ITPR3	1.64e-05	3	82	2	24904548
Pubmed	ARAF acts as a scaffold to stabilize BRAF:CRAF heterodimers.	RAF1 BRAF	1.64e-05	3	82	2	22926515
Pubmed	RAF1/BRAF dimerization integrates the signal from RAS to ERK and ROKα.	RAF1 BRAF	1.64e-05	3	82	2	28270557
Pubmed	BRAF somatic mutation contributes to intrinsic epileptogenicity in pediatric brain tumors.	BRAF REST	1.64e-05	3	82	2	30224756
Pubmed	Nilotinib and MEK inhibitors induce synthetic lethality through paradoxical activation of RAF in drug-resistant chronic myeloid leukemia.	RAF1 BRAF	1.64e-05	3	82	2	22169110
Pubmed	Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis.	ITPR1 ITPR3	1.64e-05	3	82	2	18250332
Pubmed	Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.	ITPR1 ITPR3	1.64e-05	3	82	2	9858485
Pubmed	DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification.	METTL2A METTL2B	1.64e-05	3	82	2	32427860
Pubmed	Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.	ITPR1 ITPR3	1.64e-05	3	82	2	9808793
Pubmed	CRAF gene fusions in pediatric low-grade gliomas define a distinct drug response based on dimerization profiles.	RAF1 BRAF	1.64e-05	3	82	2	28806393
Pubmed	Identification of KRAP-expressing cells and the functional relevance of KRAP to the subcellular localization of IP3R in the stomach and kidney.	ITPR1 ITPR3	1.64e-05	3	82	2	22992961
Pubmed	Mechanism of MEK inhibition determines efficacy in mutant KRAS- versus BRAF-driven cancers.	RAF1 BRAF	1.64e-05	3	82	2	23934108
Pubmed	B-RafV600E inhibits sodium iodide symporter expression via regulation of DNA methyltransferase 1.	BRAF DNMT1	1.64e-05	3	82	2	25378232
Pubmed	Egr-1 is necessary for fibroblast growth factor-2-induced transcriptional activation of the glial cell line-derived neurotrophic factor in murine astrocytes.	EGR1 FGF2	1.64e-05	3	82	2	19721135
Pubmed	Structure-based mechanism of preferential complex formation by apoptosis signal-regulating kinases.	MAP3K15 MAP3K5	1.64e-05	3	82	2	32156783
Pubmed	Sorafenib inhibits non-small cell lung cancer cell growth by targeting B-RAF in KRAS wild-type cells and C-RAF in KRAS mutant cells.	RAF1 BRAF	1.64e-05	3	82	2	19638574
Pubmed	Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.	ITPR1 ITPR3	1.64e-05	3	82	2	18194433
Pubmed	Induction of Id-1 by FGF-2 involves activity of EGR-1 and sensitizes neuroblastoma cells to cell death.	EGR1 FGF2	1.64e-05	3	82	2	21506108
Pubmed	ERK and beyond: insights from B-Raf and Raf-1 conditional knockouts.	RAF1 BRAF	1.64e-05	3	82	2	16861903
Pubmed	Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.	ITPR1 ITPR3	1.64e-05	3	82	2	12032348
Pubmed	IP3 receptors regulate vascular smooth muscle contractility and hypertension.	ITPR1 ITPR3	1.64e-05	3	82	2	27777977
Pubmed	ASK family kinases mediate cellular stress and redox signaling to circadian clock.	MAP3K15 MAP3K5	1.64e-05	3	82	2	29555767
Pubmed	Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.	ITPR1 ITPR3	1.64e-05	3	82	2	17581770
Pubmed	Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.	ITPR1 ITPR3	1.64e-05	3	82	2	18241669
Pubmed	Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.	ITPR1 ITPR3	1.64e-05	3	82	2	19068129
Pubmed	Ubiquitination and proteasomal degradation of endogenous and exogenous inositol 1,4,5-trisphosphate receptors in alpha T3-1 anterior pituitary cells.	ITPR1 ITPR3	1.64e-05	3	82	2	12421829
Pubmed	Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.	ITPR1 ITPR3	1.64e-05	3	82	2	17327232
Pubmed	Nuclear localization of endogenous RGK proteins and modulation of cell shape remodeling by regulated nuclear transport.	REM1 RRAD	1.64e-05	3	82	2	17605760
Pubmed	A scanning electron microscopic investigation of genetic emphysema in tight-skin, pallid, and beige mice, three different C57 BL/6J mutants.	FBN1 LYST	1.64e-05	3	82	2	8780155
Pubmed	Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.	ITPR1 ITPR3	1.64e-05	3	82	2	16014380
Pubmed	C-Raf is required for the initiation of lung cancer by K-Ras(G12D).	RAF1 BRAF	1.64e-05	3	82	2	22043453
Pubmed	A YWHAZ Variant Associated With Cardiofaciocutaneous Syndrome Activates the RAF-ERK Pathway.	RAF1 BRAF	1.64e-05	3	82	2	31024343
Pubmed	Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.	ITPR1 ITPR3	1.64e-05	3	82	2	17890015
Pubmed	Structure of the BRAF-MEK complex reveals a kinase activity independent role for BRAF in MAPK signaling.	RAF1 BRAF	1.64e-05	3	82	2	25155755
Cytoband	1q42.12	LIN9 DNAH14	4.73e-04	18	82	2	1q42.12
Cytoband	19q13.43	ZNF418 ZNF835 ZNF551	5.22e-04	87	82	3	19q13.43
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF462 ZNF14 ZNF326 ZNF140 ZNF680 ZNF560 EGR1 ZNF732 ZNF335 ZBTB8B ZNF521 ZNF576 ZNF736 ZNF84 ZNF418 ZNF835 ZNF551 ZNF697	6.87e-12	718	59	18	28
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	RAF1 BRAF MAP3K15 MAP3K5	1.03e-06	24	59	4	654
GeneFamily	Dyneins, axonemal	DNAH9 DNAH7 DNAH14	2.17e-05	17	59	3	536
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR1 ITPR3	3.13e-05	3	59	2	297
GeneFamily	RGK type GTPase family	REM1 RRAD	6.26e-05	4	59	2	1260
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	RAF1 BRAF	1.04e-04	5	59	2	1157
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	MSR1 SCARA5	3.49e-03	27	59	2	1253
GeneFamily	Methyltransferase like	METTL2A METTL2B	5.18e-03	33	59	2	963
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_3\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ZNF680 OAS3 PAQR3 ANO3 METTL2B ZNF697	5.54e-07	164	81	6	583dda853cee9491dbdcb228c23d8deadc20eb08
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 FBN1 SCARA5 ANO3 MAP3K5	1.39e-05	168	81	5	4b2d29a7843bf45922038c093ca7ec0600756adc
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP53 FBN1 PLPP3 SCARA5 FGF2	1.56e-05	172	81	5	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	USP53 ANO3 DNAH14 OPRK1 TG	1.84e-05	178	81	5	c655b72ec22d45d2da69c2d8886a01831ce79558
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 REM1 SCARA5 FGF2 ANO3	2.33e-05	187	81	5	0f90bce2087aecfdbb377e6f46c6e468efbb6e28
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 REM1 SCARA5 FGF2 ANO3	2.33e-05	187	81	5	76c957b2976d38adb45e07bcf96c689442e1fc20
ToppCell	facs-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 REM1 SCARA5 FGF2 ANO3	2.33e-05	187	81	5	90a1078b0303799fba5d2ca4fa12076fd75b78b1
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FBN1 SCARA5 KNDC1 PRG4 GULP1	2.39e-05	188	81	5	0e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ZNF462 FREM2 ZNF521 MAP3K5 ITPR1	2.39e-05	188	81	5	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSR1 FBN1 MAP3K5 ITPR1 GULP1	2.45e-05	189	81	5	c734e5693808a0333139e87bd5be2597a9252afe
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSR1 FBN1 MAP3K5 ITPR1 GULP1	2.58e-05	191	81	5	c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 FBN1 EGR1 SCARA5 MAP3K5	2.58e-05	191	81	5	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSR1 FBN1 MAP3K5 ITPR1 GULP1	2.58e-05	191	81	5	cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FREM2 PATJ FBN3 DNAH14 ITPR3	2.58e-05	191	81	5	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ELAPOR2 FREM2 KNDC1 DNAH14 ITPR3	2.65e-05	192	81	5	cc9911e182a289779a2612bc213daae5607689e7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 FREM2 PATJ DNAH14 ITPR3	2.65e-05	192	81	5	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 FBN1 EGR1 SCARA5 MAP3K5	2.71e-05	193	81	5	09a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	USP53 FBN1 PLPP3 SCARA5 DNMT1	2.71e-05	193	81	5	261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCell	Fetal_29-31_weeks-Epithelial\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FREM2 PATJ FBN3 DNAH14 ITPR3	2.71e-05	193	81	5	a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	USP53 PCSK5 FBN1 SCARA5 ZNF521	2.78e-05	194	81	5	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN1 EGR1 DNAH9 DNAH14 OPRK1	2.85e-05	195	81	5	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP53 PCSK5 FBN1 SCARA5 FGF2	2.85e-05	195	81	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FBN1 EGR1 DNAH9 DNAH14 OPRK1	2.85e-05	195	81	5	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP53 PLPP3 EGR1 FGF2 PRG4	2.99e-05	197	81	5	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial-Astrocyte\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	PLPP3 OSBPL1A ZNF521 REST GULP1	3.07e-05	198	81	5	bfad1c51cf884ff7ce89f8278820800582541dc7
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Macroglial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	PLPP3 OSBPL1A ZNF521 REST GULP1	3.07e-05	198	81	5	6372e65242236c497d9b3be147092897c1609d22
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 PLPP3 SCARA5 PRG4 GULP1	3.07e-05	198	81	5	a9afedbc0556faf4a46f7bf28f4a9adb3bc859d8
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 PLPP3 SCARA5 PRG4 GULP1	3.07e-05	198	81	5	7b5350768f306ec528e271d2ac4470bf668ec6f0
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	FBN1 ZNF521 MAP3K15 PRG4 HCRTR2	3.14e-05	199	81	5	07b8c33342c62afd9c63ec2d757cfa3ba65d2a98
ToppCell	cellseq-Mesenchymal-Fibroblastic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	USP53 FBN1 PLPP3 SCARA5 PRG4	3.22e-05	200	81	5	8978867bf69c830b1e48cac2ad6b512dbe60f149
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FBN1 REM1 CASP1 RRAD MAP3K5	3.22e-05	200	81	5	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1-AF2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 PLPP3 EGR1 SCARA5 PRG4	3.22e-05	200	81	5	44317fbf4d1480a37b50ab2777bf1a3e4fc0c05f
ToppCell	Biopsy_IPF-Mesenchymal\|Biopsy_IPF / Sample group, Lineage and Cell type	FBN1 PLPP3 SCARA5 FGF2 PRG4	3.22e-05	200	81	5	bb605b373caf3f873dc1b87d712704568e0d6040
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	FBN1 REM1 CASP1 RRAD MAP3K5	3.22e-05	200	81	5	a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	USP53 FBN1 PLPP3 EGR1 SCARA5	3.22e-05	200	81	5	5fdca7959134a5c8e06e5d6d14aafe34b963aef2
ToppCell	Kidney-Fibroblasts\|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.	FBN1 TOPAZ1 SCARA5 PRG4 ZNF835	3.22e-05	200	81	5	2c265ad8314a21bce50ac21b16da2fea125366ea
ToppCell	cellseq2-Mesenchymal-Fibroblastic\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 PLPP3 EGR1 SCARA5 PRG4	3.22e-05	200	81	5	1c10597edd532bf172ca09870a937d35e2585081
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FBN1 PLPP3 EGR1 SCARA5 PRG4	3.22e-05	200	81	5	440dda48b09c6a8581b7ca634b0d67f1ecacf65e
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-mesenchymal_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLPP3 SCARA5 PRG4 GULP1	8.26e-05	126	81	4	c3261ea8726400de87f1c8a5a5134ba2b2884f66
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP53 REM1 ANO3 TG	2.12e-04	161	81	4	1b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ELAPOR2 FREM2 DNAH9 TEX19	2.17e-04	162	81	4	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|356C / Donor, Lineage, Cell class and subclass (all cells)	RAF1 METTL2B ZNF697 TG	2.33e-04	165	81	4	35a6de30438de364ccca948fc932da541a69ef89
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 SCARA5 PRG4	2.33e-04	165	81	4	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	COVID-19_Severe-CD4+_T_activated\|COVID-19_Severe / Disease condition and Cell class	MARF1 OAS3 PATJ ZNF697	2.38e-04	166	81	4	0f138dbafad6f83975944e8f6398411127b150cc
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_ETV4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ANO3 DNAH14 HCRTR2	2.55e-04	169	81	4	716e9d4c5fb99c56b76afaa5ed90bfa859fde802
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP53 ITGB1BP2 MAP3K15 PATJ	2.61e-04	170	81	4	d99f61aa85ea3f775165cb433421e6f1cda4f96b
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP53 ITGB1BP2 MAP3K15 PATJ	2.61e-04	170	81	4	615cf9639c66b3fbd984ebe3f345280005d3c38a
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 FBN1 SCARA5 MAP3K5	2.67e-04	171	81	4	5d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ZNF680 LYST LIN9 ZNF551	2.85e-04	174	81	4	ccc79febfcf588d8294ffc712338be96de8a5033
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCTD19 RASAL2 MAP3K5 ITPR3	2.85e-04	174	81	4	42735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PCSK5 ANO3 DNAH14 HCRTR2	2.85e-04	174	81	4	7d4b860e05b5931f6f9d757a68f75ff35597a47a
ToppCell	severe_COVID-19-HSPC\|severe_COVID-19 / disease group, cell group and cell class (v2)	ZNF462 FBN1 ZNF521 ABCC11	2.85e-04	174	81	4	6d35bacf073537b272ff821e604c899fb9ce6a7c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ZNF732 ANO3 RASAL2	2.98e-04	176	81	4	9bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ZNF732 ANO3 RASAL2	2.98e-04	176	81	4	3f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO3 DNAH14 OPRK1 GULP1	3.04e-04	177	81	4	921783ed0fe20294d2f384d9136924b679df01bb
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO3 DNAH14 OPRK1 GULP1	3.11e-04	178	81	4	6f61490d79cd1727ed2d5cc673823dd4efdafac1
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FREM2 OR5C1 FBN3 OPRK1	3.38e-04	182	81	4	724c33ad2fb525cbcfa5efa3362675eb42a5636d
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSR1 REM1 LYST DNMT1	3.38e-04	182	81	4	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FBN1 SCARA5 ZNF521 PRG4	3.45e-04	183	81	4	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO3 DNAH14 OPRK1 TG	3.52e-04	184	81	4	9a185e6ea86bbfbb48bfe88650a8c05ceba78d7f
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	FBN1 SCARA5 FGF2 PRG4	3.60e-04	185	81	4	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PLPP3 FGF2 PRG4 ZNF697	3.60e-04	185	81	4	9878392d79734ab5bb977d7f4f5e2e079b9a5353
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FREM2 PATJ FBN3 DNAH14	3.67e-04	186	81	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EGR1 OSBPL1A ANO3 ITPR1	3.67e-04	186	81	4	56c139e679d640ea901ead657a8e8887e0fca098
ToppCell	343B-Fibroblasts-Fibroblast-E-\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 SCARA5 OSBPL1A ZNF418	3.67e-04	186	81	4	1bac7825c2fe3e6cdff65026b09b9ccaa40fa27f
ToppCell	343B-Fibroblasts-Fibroblast-E\|343B / Donor, Lineage, Cell class and subclass (all cells)	FBN1 SCARA5 OSBPL1A ZNF418	3.67e-04	186	81	4	59db239f1864a5d4f1570c93219dbd7ac5b6db35
ToppCell	NS-moderate-d_07-13-Epithelial-Ciliated\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KNDC1 RRAD DNAH9 DNAH7	3.67e-04	186	81	4	85787ff207f109ec7e3c0f729ba9bda739c2fdc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ANO3 LIN9 FANCA	3.75e-04	187	81	4	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBN1 ANO3 LIN9 FANCA	3.75e-04	187	81	4	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 FREM2 PATJ ITPR3	3.75e-04	187	81	4	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	pdx-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ZNF462 FREM2 ZNF521 ITPR1	3.75e-04	187	81	4	7e376831a11ee72ed87abcdac631ca46ae29c250
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	FBN1 SCARA5 FGF2 PRG4	3.82e-04	188	81	4	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.90e-04	189	81	4	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	FBN1 PLPP3 SCARA5 PRG4	3.90e-04	189	81	4	c392491aabe8a3e90974ab2ea123bbbe5200439d
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	dc7e92f1b18d0f5efec11d09d56ba954d4f8b3bd
ToppCell	facs-SCAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	0bb06df3d5a50416854370f234718c6cec3d773b
ToppCell	facs-SCAT-Fat-24m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	008290bb5c79446681dd6bf354336c57ad0d6f13
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 SCARA5 PRG4	3.98e-04	190	81	4	d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	PLPP3 EGR1 LYST MAP3K5	3.98e-04	190	81	4	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSR1 FBN1 MAP3K5 ITPR1	3.98e-04	190	81	4	2e592323085ba9c019d678ac2a784462ab470ed9
ToppCell	droplet-Limb_Muscle\|droplet / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 RRAD PRG4	3.98e-04	190	81	4	06c2b13fa88abbcb8086f13b8d98a156e41e4198
ToppCell	facs-GAT-Fat-24m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	3720e64129f3f3268b1dc14031a76f41c38241c2
ToppCell	facs-GAT-Fat-24m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	73a50426f972f08f9bb525ad5c0b774187ab5d6a
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	facs-GAT-Fat-24m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	b55cf1fb586b724295b7b038483249847bb344fc
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSR1 FBN1 MAP3K5 ITPR1	3.98e-04	190	81	4	445952b70abffadb6ccc1ed4bbf61a88b06b73b3
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	3.98e-04	190	81	4	47077579496c5340e99f61499427a3a36b566da3
ToppCell	droplet-Mammary_Gland-nan-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	4.06e-04	191	81	4	8022059e434fd411dc539819f969bd4f94861281
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ELAPOR2 FREM2 PATJ DNAH14	4.06e-04	191	81	4	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FREM2 PATJ DNAH7 OPRK1	4.06e-04	191	81	4	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	4.06e-04	191	81	4	a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCell	ASK440-Mesenchymal\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBN1 PLPP3 ABCC11 PRG4	4.06e-04	191	81	4	f12959eebb4167e1aa03de05d7711a702c58b3c9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MSR1 FBN1 MAP3K5 ITPR1	4.06e-04	191	81	4	806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCell	COPD-Endothelial-VE_Arterial\|Endothelial / Disease state, Lineage and Cell class	PCSK5 EGR1 FGF2 LYST	4.06e-04	191	81	4	ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBN1 PLPP3 EGR1 SCARA5	4.06e-04	191	81	4	19c67a812b8ce97472d316acd15aeefe8736000d
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	FREM2 PATJ FBN3 DNAH14	4.06e-04	191	81	4	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	ASK440-Mesenchymal-Fibroblast\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	FBN1 PLPP3 ABCC11 PRG4	4.06e-04	191	81	4	387296b5377ef6839f0812e5b3529a10b5f7d530
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ELAPOR2 FREM2 PATJ DNAH14	4.06e-04	191	81	4	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FBN1 PLPP3 EGR1 SCARA5	4.14e-04	192	81	4	29bee88b45e23f16543ffc7cc361bc5da5d16a2b
Computational	Genes in the cancer module 568.	RYBP CAPN3 CASP1 PYGB	1.64e-04	73	41	4	MODULE_568
Computational	Genes in the cancer module 491.	RYBP CAPN3 CASP1 PYGB	2.23e-04	79	41	4	MODULE_491
Drug	9 mM of H	CAPN3 ITPR1 ITPR3	2.31e-06	8	80	3	CID000130464
Drug	Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A	PLPP3 CASP1 LYST RASAL2 MAP3K5 ITPR3 GULP1	6.08e-06	197	80	7	3234_DN
Drug	4-chloro-m-cresol	REM1 RRAD ITPR1 ITPR3	8.54e-06	37	80	4	CID000001732
Drug	Isocaffeine	ITPR1 ITPR3	1.22e-05	2	80	2	CID000001326
Drug	adenophostin B	ITPR1 ITPR3	1.22e-05	2	80	2	CID000656722
Drug	Asp-tyr	LIN9 TG	1.22e-05	2	80	2	CID000152455
Drug	benzene 1,2,4-trisphosphate	ITPR1 ITPR3	1.22e-05	2	80	2	CID000192376
Drug	Gvapspat amide	PYGB ITPR1 ITPR3	1.84e-05	15	80	3	CID000125015
Drug	vinylene	ZNF462 ZNF326 AKAP8 EGR1 ZNF335 REST ZNF418	2.50e-05	245	80	7	CID000006326
Drug	5-deoxy-5-fluoro-myo-inositol	ITPR1 ITPR3	3.65e-05	3	80	2	CID000195110
Drug	NSC612112	LYST OPRK1	3.65e-05	3	80	2	CID000356432
Disease	prostate adenocarcinoma (is_implicated_in)	RAF1 BRAF FGF2	1.67e-05	20	74	3	DOID:2526 (is_implicated_in)
Disease	Noonan syndrome with multiple lentigines	RAF1 BRAF	1.86e-05	3	74	2	cv:C0175704
Disease	connective tissue disease (implicated_via_orthology)	FBN1 FBN3	1.86e-05	3	74	2	DOID:65 (implicated_via_orthology)
Disease	bronchiolo-alveolar adenocarcinoma (is_marker_for)	EGR1 DNMT1	3.71e-05	4	74	2	DOID:4926 (is_marker_for)
Disease	excessive daytime sleepiness measurement	MSR1 PATJ HCRTR2	7.83e-05	33	74	3	EFO_0007875
Disease	liver cirrhosis (biomarker_via_orthology)	FBN1 EGR1 DNMT1	8.57e-05	34	74	3	DOID:5082 (biomarker_via_orthology)
Disease	attempted suicide	PCSK5 ELAPOR2 FBN1 ANO3 HCRTR2	8.69e-05	178	74	5	EFO_0004321
Disease	Leopard Syndrome 1	RAF1 BRAF	9.25e-05	6	74	2	C4551484
Disease	amphetamine abuse (implicated_via_orthology)	MAP3K15 MAP3K5	9.25e-05	6	74	2	DOID:670 (implicated_via_orthology)
Disease	Pilomyxoid astrocytoma	RAF1 BRAF	1.29e-04	7	74	2	C1519086
Disease	sleep duration, circadian rhythm, excessive daytime sleepiness measurement, insomnia measurement	PATJ HCRTR2	1.72e-04	8	74	2	EFO_0004354, EFO_0005271, EFO_0007875, EFO_0007876
Disease	Noonan syndrome	RAF1 BRAF	2.21e-04	9	74	2	cv:C0028326
Disease	Turner Syndrome, Male	RAF1 BRAF	3.36e-04	11	74	2	C0041409
Disease	Female Pseudo-Turner Syndrome	RAF1 BRAF	3.36e-04	11	74	2	C1527404
Disease	Noonan Syndrome 1	RAF1 BRAF	3.36e-04	11	74	2	C4551602
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR1 ITPR3	4.03e-04	12	74	2	DOID:1441 (implicated_via_orthology)
Disease	RASopathy	RAF1 BRAF	6.38e-04	15	74	2	cv:C5555857
Disease	Non-Small Cell Lung Carcinoma	ZNF462 RAF1 BRAF RRAD	6.49e-04	156	74	4	C0007131
Disease	Malignant Glioma	RAF1 BRAF FGF2	7.35e-04	70	74	3	C0555198
Disease	mixed gliomas	RAF1 BRAF FGF2	7.35e-04	70	74	3	C0259783
Disease	Prostatic Neoplasms	MSR1 BRAF EGR1 FGF2 PATJ DNMT1 ITPR1	8.97e-04	616	74	7	C0033578
Disease	Malignant neoplasm of prostate	MSR1 BRAF EGR1 FGF2 PATJ DNMT1 ITPR1	8.97e-04	616	74	7	C0376358
Disease	Noonan-Like Syndrome With Loose Anagen Hair	RAF1 BRAF	1.03e-03	19	74	2	C3501846
Disease	Costello syndrome (disorder)	RAF1 BRAF	1.03e-03	19	74	2	C0587248
Disease	Noonan syndrome-like disorder with loose anagen hair	RAF1 BRAF	1.03e-03	19	74	2	C1843181
Disease	Cardio-facio-cutaneous syndrome	RAF1 BRAF	1.03e-03	19	74	2	C1275081
Disease	Adenocarcinoma of prostate	BRAF FANCA	1.14e-03	20	74	2	C0007112
Disease	heel bone mineral density, urate measurement	MSR1 MINDY4 LIN9 DNAH14	1.15e-03	182	74	4	EFO_0004531, EFO_0009270
Disease	Cardiac Hypertrophy	PLPP3 FGF2 RRAD	1.16e-03	82	74	3	C1383860
Disease	Cardiomegaly	PLPP3 FGF2 RRAD	1.16e-03	82	74	3	C0018800
Disease	Glioma	RAF1 BRAF FGF2	1.38e-03	87	74	3	C0017638
Disease	LEOPARD Syndrome	RAF1 BRAF	1.39e-03	22	74	2	C0175704
Disease	Kidney Diseases	PCSK5 CASP1 FGF2	1.43e-03	88	74	3	C0022658
Disease	Noonan Syndrome	RAF1 BRAF	1.65e-03	24	74	2	C0028326
Disease	Endogenous Hyperinsulinism	FBN1 FANCA	1.94e-03	26	74	2	C1257963
Disease	Exogenous Hyperinsulinism	FBN1 FANCA	1.94e-03	26	74	2	C1257964
Disease	Compensatory Hyperinsulinemia	FBN1 FANCA	1.94e-03	26	74	2	C1257965
Disease	Visual seizure	FGF2 REST OPRK1	2.12e-03	101	74	3	C0270824
Disease	Epileptic drop attack	FGF2 REST OPRK1	2.12e-03	101	74	3	C0270846
Disease	Generalized seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C0234533
Disease	Clonic Seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C0234535
Disease	Vertiginous seizure	FGF2 REST OPRK1	2.12e-03	101	74	3	C0422855
Disease	Gustatory seizure	FGF2 REST OPRK1	2.12e-03	101	74	3	C0422854
Disease	Seizures, Somatosensory	FGF2 REST OPRK1	2.12e-03	101	74	3	C0422850
Disease	Olfactory seizure	FGF2 REST OPRK1	2.12e-03	101	74	3	C0422853
Disease	Seizures, Auditory	FGF2 REST OPRK1	2.12e-03	101	74	3	C0422852
Disease	Generalized Absence Seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C4505436
Disease	Convulsive Seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C0751494
Disease	Seizures, Sensory	FGF2 REST OPRK1	2.12e-03	101	74	3	C0751496
Disease	Jacksonian Seizure	FGF2 REST OPRK1	2.12e-03	101	74	3	C0022333
Disease	Non-epileptic convulsion	FGF2 REST OPRK1	2.12e-03	101	74	3	C0751056
Disease	Atonic Absence Seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C0751123
Disease	Complex partial seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C0149958
Disease	Single Seizure	FGF2 REST OPRK1	2.12e-03	101	74	3	C0751110
Disease	Epileptic Seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C4317109
Disease	Nonepileptic Seizures	FGF2 REST OPRK1	2.12e-03	101	74	3	C3495874
Disease	Tonic Seizures	FGF2 REST OPRK1	2.18e-03	102	74	3	C0270844
Disease	Absence Seizures	FGF2 REST OPRK1	2.18e-03	102	74	3	C4316903
Disease	Convulsions	FGF2 REST OPRK1	2.18e-03	102	74	3	C4048158
Disease	Hyperinsulinism	FBN1 FANCA	2.25e-03	28	74	2	C0020459
Disease	Seizures, Focal	FGF2 REST OPRK1	2.30e-03	104	74	3	C0751495
Disease	Myoclonic Seizures	FGF2 REST OPRK1	2.30e-03	104	74	3	C4317123
Disease	Tonic - clonic seizures	FGF2 REST OPRK1	2.30e-03	104	74	3	C0494475
Disease	selenium measurement	ZNF14 ZNF521	2.41e-03	29	74	2	EFO_0006331

Protein segments in the cluster

Peptide	Gene	Start	Entry
LCIKQEDSLFSEFCD	C21orf140	96	B9A014
TFFTLAFCDFCRKLL	BRAF	241	P15056
EDNKFKFCVSCARLA	DNMT1	886	P26358
DRIQFACSVCKFRSF	AKAP8	386	O43823
ACSVCKFRSFDDEEI	AKAP8	391	O43823
CSCSFRVLVVSAKFE	BOLA2	31	Q9H3K6
DFDECTTLVGQVCRF	FBN3	1886	Q75N90
VLRCSFADLSDFCLA	ANO3	91	Q9BYT9
RKVDSAVFCLCLDDF	CPT2	316	P23786
FARKTFLKLAFCDIC	RAF1	141	P04049
TTCFICGLERDKFDN	ITPR3	2536	Q14573
CECSEFRFIVNFLRS	KCTD19	206	Q17RG1
SREDFVICSICLFCF	PAQR3	101	Q6TCH7
FLVFCIFADSECLLL	OR5W2	101	Q8NH69
CAVVFDCKFIETSAA	RRAD	221	P55042
AKGDFVCIFCDRSFR	REST	1056	Q13127
FEGDNDFCVCLKESF	LIN9	136	Q5TKA1
SCCRKRTVDFSEFLN	ITGB1BP2	41	Q9UKP3
SCLLCIFKREFDESN	ITPR1	1001	Q14643
LGDSFYCSIEKVFLC	FREM2	2906	Q5SZK8
FACDICGRKFARSDE	EGR1	396	P18146
FFFCARDVATVFTLC	PCNX3	896	Q9H6A9
SCDRFFFLLRSKGEC	PCSK5	1586	Q92824
LKGDNFFRFTCSDCS	KAT14	96	Q9H8E8
FFRFTCSDCSADGKE	KAT14	101	Q9H8E8
SRCFAFVHDLCDEEK	METTL2B	231	Q6P1Q9
CFALFLSECVKSLSF	ABCC11	206	Q96J66
KYFCELCLDDTLFAR	RASAL2	186	Q9UJF2
SFCRSRKINSFFCDI	OR5C1	171	Q8NGR4
VKSTDSCLFFIKCFD	OSBPL1A	291	Q9BXW6
SCLFFIKCFDDTIHG	OSBPL1A	296	Q9BXW6
GRITFVFETLCSADC	ELAPOR2	511	A8MWY0
SRCFAFVHDLCDEEK	METTL2A	231	Q96IZ6
EVFCFGRESSIEECK	MSR1	416	P21757
CELLFFFKELCSFSQ	PPP4R3C	331	Q6ZMV5
FREEFKAAFSCCCLG	HCRTR2	371	O43614
TLASCRDTLNFCFKE	CCDC105	226	Q8IYK2
ACSCDVEEIFRKVRF	CASP1	361	P29466
FKCRCDSGFALDSEE	FBN1	1051	P35555
TRDSLFFCLKFCTAA	FANCA	826	O15360
CADDKTDKRIFTFIC	GULP1	101	Q9UBP9
CRSLFEKDKLLFSFC	DNAH7	3271	Q8WXX0
NEDKLCFSFRLCTVI	DNAH14	2811	Q0VDD8
FLCVAFLCVSKEAES	LYST	901	Q99698
FFKGHREAEFICVCD	MARF1	381	Q9Y4F3
ASKCVTDECFFFERL	FGF2	226	P09038
FATFCGAISEKFCDL	KNDC1	931	Q76NI1
CSRETEFKSILFALC	DNAH9	4041	Q9NYC9
NIDFDSFICCFVRLE	CAPN3	776	P20807
ACKGTEETIFRCSFS	SCARA5	461	Q6ZMJ2
ARACAIFCVDEIVVF	SPOUT1	101	Q5T280
RACAVVFDCKFIETS	REM1	211	O75628
AVDTICSFLKENCFR	OAS3	776	Q9Y6K5
AFLDENFKRCFRDFC	OPRK1	331	P41145
GVSISKFEERCCFLY	MAP3K5	611	Q99683
GISLSKFDERCCFLY	MAP3K15	581	Q6ZN16
CAREFEALRSCFAAA	NDUFAF8	51	A1L188
VACCIVFFVSDLFKT	PLPP3	266	O14495
DCSVCTFRNSAEAFK	RYBP	26	Q8N488
TFRNSAEAFKCSICD	RYBP	31	Q8N488
AELSCKGRCFESFER	PRG4	66	Q92954
DTVFTRCNCEGKTFF	PRG4	1196	Q92954
DACIFCALKTIFAQF	USP53	71	Q70EK8
KTLLFGSSFCCFNEE	MINDY4	416	Q4G0A6
FTLVCCRRLFDDEAS	PATJ	631	Q8NI35
FFRCTLCQEVFDSKV	ZNF521	721	Q96K83
CLDTVLAREADFCFR	VPS18	421	Q9P253
ECSECEKSFSRKFIL	ZNF551	476	Q7Z340
KFGCRDPVRTCFETF	PYGB	316	P11216
GCSDCRKAFFEKSEL	ZNF84	376	P51523
RCGQCEKRFSDFSTL	ZNF697	466	Q5TEC3
EKFADFQTFCACIAE	TOPAZ1	1311	Q8N9V7
YECRECGKFFSSLLE	ZNF418	566	Q8TF45
ACAECDKAFSRSFSL	ZNF140	386	P52738
ECSACAKAFRFSSAL	ZNF835	251	Q9Y2P0
FRCIKCFKLSFSTAE	ZNF462	1846	Q96JM2
FCFKAIRCEKEEAAT	TRAPPC8	1156	Q9Y2L5
CTRCLITFADSKFQE	ZNF576	36	Q9H609
TCEECGKAFSRFTTL	ZNF732	391	B4DXR9
VANRRFKCEFCEFVC	ZNF335	616	Q9H4Z2
EKSISNGFFECERRC	TG	1986	P01266
FKCEECGKAFSLFSI	ZNF680	266	Q8NEM1
LSICFTCFKAAFLDF	TEX19	31	Q8NA77
KRFDCDQCGKVFVSF	ZNF560	486	Q96MR9
CKECGKAFSFLSSFR	ZNF14	281	P17017
EECGKDCRLFSDFTR	ZNF736	176	B4DX44
EQRKRDFFCDCSIIV	ZBTB8B	16	Q8NAP8
DFFCDCSIIVEGRIF	ZBTB8B	21	Q8NAP8
AFTCSFCKFRTFEEK	ZNF326	311	Q5BKZ1