Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionMHC class II receptor activity

HLA-DOA HLA-DQA2 HLA-DRA

6.96e-0611713GO:0032395
GeneOntologyMolecularFunctionproteasome binding

USP13 PSME4 SACS

4.70e-0520713GO:0070628
GeneOntologyMolecularFunctionMHC class II protein complex binding

HLA-DOA HLA-DQA2 HLA-DRA

1.19e-0427713GO:0023026
GeneOntologyMolecularFunctionMHC protein complex binding

HLA-DOA HLA-DQA2 HLA-DRA

4.17e-0441713GO:0023023
GeneOntologyMolecularFunctiontransferase activity, transferring phosphorus-containing groups

SCYL2 HIPK3 PIKFYVE TGFBR1 MAST4 RPAP1 IKBKE RIPK2 ALDH18A1 FHIT TENT2

4.48e-049387111GO:0016772
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen via MHC class II

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

4.56e-0632724GO:0019886
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class II

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

7.39e-0636724GO:0002495
GeneOntologyBiologicalProcessantigen processing and presentation of peptide or polysaccharide antigen via MHC class II

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

9.21e-0638724GO:0002504
GeneOntologyBiologicalProcessMHC class II protein complex assembly

HLA-DOA HLA-DQA2 HLA-DRA

2.21e-0516723GO:0002399
GeneOntologyBiologicalProcesspeptide antigen assembly with MHC class II protein complex

HLA-DOA HLA-DQA2 HLA-DRA

2.21e-0516723GO:0002503
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

2.36e-0548724GO:0002478
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous antigen

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

5.02e-0558724GO:0019884
GeneOntologyBiologicalProcessMHC protein complex assembly

HLA-DOA HLA-DQA2 HLA-DRA

5.18e-0521723GO:0002396
GeneOntologyBiologicalProcesspeptide antigen assembly with MHC protein complex

HLA-DOA HLA-DQA2 HLA-DRA

5.18e-0521723GO:0002501
GeneOntologyBiologicalProcesscalcium-independent cell-matrix adhesion

PKD1 VWA2

7.18e-054722GO:0007161
GeneOntologyBiologicalProcesspeptidyl-serine phosphorylation

HIPK3 PIKFYVE TGFBR1 MAST4 IKBKE PKD1 RIPK2

9.73e-05307727GO:0018105
GeneOntologyBiologicalProcesspeptidyl-serine modification

HIPK3 PIKFYVE TGFBR1 MAST4 IKBKE PKD1 RIPK2

1.23e-04319727GO:0018209
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

1.45e-0476724GO:0048002
GeneOntologyCellularComponentMHC class II protein complex

HLA-DOA HLA-DQA2 HLA-DRA

2.57e-0517723GO:0042613
GeneOntologyCellularComponentMHC protein complex

HLA-DOA HLA-DQA2 HLA-DRA

9.62e-0526723GO:0042611
HumanPhenoParietal cortical atrophy

SCYL2 SACS OCA2

5.76e-068253HP:0012104
DomainC1-set_C

HLA-DOA HLA-DQA2 HLA-DRA

5.24e-075713PF16196
DomainC1-set_C

HLA-DOA HLA-DQA2 HLA-DRA

5.24e-075713IPR032431
DomainMHC_II_alpha

HLA-DOA HLA-DQA2 HLA-DRA

5.24e-075713SM00920
DomainMHC_II_alpha

HLA-DOA HLA-DQA2 HLA-DRA

1.04e-066713PF00993
DomainMHC_II_a_N

HLA-DOA HLA-DQA2 HLA-DRA

1.82e-067713IPR001003
DomainMHC_II_a/b_N

HLA-DOA HLA-DQA2 HLA-DRA

1.86e-0514713IPR014745
Domain-

HLA-DOA HLA-DQA2 HLA-DRA

1.86e-05147133.10.320.10
DomainARM-type_fold

SCYL2 IPO5 SAAL1 PSME4 FRYL IPO4 RALGAPA2 CLHC1

4.27e-05339718IPR016024
DomainBAGE

BAGE2 BAGE3

1.41e-045712IPR012530
DomainBAGE

BAGE2 BAGE3

1.41e-045712PF08180
DomainHEAT_REPEAT

SCYL2 IPO5 PSME4 IPO4

1.45e-0470714PS50077
Domain-

SCYL2 IPO5 SAAL1 PSME4 FRYL IPO4

1.98e-042227161.25.10.10
DomainMHC_I/II-like_Ag-recog

HLA-DOA HLA-DQA2 HLA-DRA

4.04e-0438713IPR011162
DomainARM-like

SCYL2 IPO5 SAAL1 PSME4 FRYL IPO4

5.63e-04270716IPR011989
DomainHEAT

SCYL2 IPO5 IPO4

8.05e-0448713PF02985
DomainC1-set

HLA-DOA HLA-DQA2 HLA-DRA

1.14e-0354713PF07654
DomainIMPORTIN_B_NT

IPO5 IPO4

1.26e-0314712PS50166
DomainIGc1

HLA-DOA HLA-DQA2 HLA-DRA

1.26e-0356713SM00407
DomainHEAT

SCYL2 IPO5 IPO4

1.40e-0358713IPR000357
DomainIg_C1-set

HLA-DOA HLA-DQA2 HLA-DRA

1.40e-0358713IPR003597
DomainIg/MHC_CS

HLA-DOA HLA-DQA2 HLA-DRA

1.40e-0358713IPR003006
DomainIG_MHC

HLA-DOA HLA-DQA2 HLA-DRA

1.54e-0360713PS00290
DomainImportin-beta_N

IPO5 IPO4

1.87e-0317712IPR001494
DomainAld_DH_C

ALDH18A1 ALDH3A1

2.34e-0319712IPR016163
DomainAld_DH_N

ALDH18A1 ALDH3A1

2.34e-0319712IPR016162
DomainAld_DH/histidinol_DH

ALDH18A1 ALDH3A1

2.34e-0319712IPR016161
Domain-

ALDH18A1 ALDH3A1

2.34e-03197123.40.605.10
DomainAldedh

ALDH18A1 ALDH3A1

2.34e-0319712PF00171
DomainAldehyde_DH_dom

ALDH18A1 ALDH3A1

2.34e-0319712IPR015590
Domain-

ALDH18A1 ALDH3A1

2.34e-03197123.40.309.10
DomainS_TKc

SCYL2 HIPK3 TGFBR1 MAST4 IKBKE RIPK2

2.42e-03359716SM00220
DomainPkinase

SCYL2 HIPK3 TGFBR1 MAST4 IKBKE RIPK2

3.25e-03381716PF00069
PathwayKEGG_MEDICUS_PATHOGEN_HTLV_1_TAX_TO_NFY_MEDIATED_TRANSCRIPTION

HLA-DOA HLA-DQA2 HLA-DRA

1.44e-0515463M47588
PathwayKEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_II_MOLECULES

HLA-DOA HLA-DQA2 HLA-DRA

1.44e-0515463M47604
PathwayKEGG_LEISHMANIA_INFECTION

HLA-DOA HLA-DQA2 HLA-DRA ITGAM

8.68e-0572464M3126
PathwayKEGG_ASTHMA

HLA-DOA HLA-DQA2 HLA-DRA

1.24e-0430463M13950
PathwayBIOCARTA_NUCLEARRS_PATHWAY

ABCC3 ABCA1 CYP3A4

1.66e-0433463MM1448
PathwayBIOCARTA_NUCLEARRS_PATHWAY

ABCC3 ABCA1 CYP3A4

1.81e-0434463M16393
PathwayWP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY

ABCC3 ABCA1 CYP3A4

1.98e-0435463M39488
PathwayWP_ALLOGRAFT_REJECTION

HLA-DOA HLA-DQA2 HLA-DRA C6

1.98e-0489464M39398
PathwayKEGG_ALLOGRAFT_REJECTION

HLA-DOA HLA-DQA2 HLA-DRA

2.34e-0437463M18615
PathwayREACTOME_DOWNSTREAM_TCR_SIGNALING

PSME4 HLA-DQA2 HLA-DRA RIPK2

2.34e-0493464MM14806
PathwayKEGG_GRAFT_VERSUS_HOST_DISEASE

HLA-DOA HLA-DQA2 HLA-DRA

3.18e-0441463M13519
PathwayKEGG_TYPE_I_DIABETES_MELLITUS

HLA-DOA HLA-DQA2 HLA-DRA

3.66e-0443463M12617
PathwayWP_MISMATCH_REPAIR

LIG1 MSH6

3.70e-049462MM15932
PathwayREACTOME_TCR_SIGNALING

PSME4 HLA-DQA2 HLA-DRA RIPK2

4.61e-04111464MM14803
PathwayKEGG_INTESTINAL_IMMUNE_NETWORK_FOR_IGA_PRODUCTION

HLA-DOA HLA-DQA2 HLA-DRA

5.07e-0448463M615
PathwayKEGG_AUTOIMMUNE_THYROID_DISEASE

HLA-DOA HLA-DQA2 HLA-DRA

6.43e-0452463M13103
PathwayREACTOME_TCR_SIGNALING

PSME4 HLA-DQA2 HLA-DRA RIPK2

6.99e-04124464M15381
PathwayWP_EBOLA_VIRUS_INFECTION_IN_HOST

HLA-DOA IKBKE HLA-DQA2 HLA-DRA

8.11e-04129464M39693
PathwayKEGG_CELL_ADHESION_MOLECULES_CAMS

HLA-DOA HLA-DQA2 HLA-DRA ITGAM

9.09e-04133464M16476
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

ABCC3 CYP3A4

9.25e-0414462M39328
PathwayREACTOME_MISMATCH_REPAIR

LIG1 MSH6

1.06e-0315462M27442
PathwayREACTOME_MISMATCH_REPAIR

LIG1 MSH6

1.06e-0315462MM15184
PathwayKEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS

HLA-DOA HLA-DQA2 HLA-DRA C6

1.07e-03139464M4741
PathwayREACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

PSME4 ALDH18A1 OCA2 DHTKD1 DDC RPL7A

1.15e-03366466M727
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

CFLAR ARHGEF19 IKBKE RIPK2

1.16e-03142464MM15431
PathwayREACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES

PSME4 ALDH18A1 OCA2 DHTKD1 DDC

1.17e-03245465MM15403
PathwayREACTOME_TRANSLOCATION_OF_ZAP_70_TO_IMMUNOLOGICAL_SYNAPSE

HLA-DQA2 HLA-DRA

1.21e-0316462MM14808
PathwayWP_DRUG_INDUCTION_OF_BILE_ACID_PATHWAY

ABCC3 CYP3A4

1.37e-0317462M39666
PathwayKEGG_VIRAL_MYOCARDITIS

HLA-DOA HLA-DQA2 HLA-DRA

1.53e-0370463M12294
PathwayKEGG_PHENYLALANINE_METABOLISM

ALDH3A1 DDC

1.54e-0318462M16650
PathwayREACTOME_DEATH_RECEPTOR_SIGNALING

CFLAR ARHGEF19 IKBKE RIPK2

1.56e-03154464M27697
Pubmed

HIV-1 Nef impairs MHC class II antigen presentation and surface expression.

HLA-DOA HLA-DQA2 HLA-DRA

2.01e-061274311593029
Pubmed

Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.

HLA-DOA HLA-DQA2 HLA-DRA

2.01e-061274312970439
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

TGFBR1 LIG1 MSH6 ABCA1 ERCC3 CYP3A4 OCA2 CDC25B

3.24e-0642174819692168
Pubmed

HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4.

HLA-DOA HLA-DQA2 HLA-DRA

3.31e-06147437512597
Pubmed

Interaction of CD4 with HLA class II antigens and HIV gp120.

HLA-DOA HLA-DQA2 HLA-DRA

3.31e-06147431869305
Pubmed

Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

HLA-DOA HLA-DQA2 HLA-DRA

3.31e-061474321804548
Pubmed

HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-06157438376762
Pubmed

Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-06157438168144
Pubmed

Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-061574322860026
Pubmed

Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-06157437602119
Pubmed

HIV-gp120 can block CD4-class II MHC-mediated adhesion.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-06157431967269
Pubmed

The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-06157439079699
Pubmed

AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-06157433489470
Pubmed

Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging.

HLA-DOA HLA-DQA2 HLA-DRA

4.13e-061574310729169
Pubmed

Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.

TGFBR1 PKD1

4.47e-06274227020852
Pubmed

Evidence for more than one Parkinson's disease-associated variant within the HLA region.

HLA-DQA2 HLA-DRA

4.47e-06274222096524
Pubmed

Novel insulin-elicited phosphoproteins in adipocytes.

TBC1D4 RALGAPA2

4.47e-06274215451025
Pubmed

Inhibition of CD4+ T cell function by the HIV envelope protein, gp120.

HLA-DOA HLA-DQA2 HLA-DRA

5.08e-06167432846691
Pubmed

Identification and structural analysis of residues in the V1 region of CD4 involved in interaction with human immunodeficiency virus envelope glycoprotein gp120 and class II major histocompatibility complex molecules.

HLA-DOA HLA-DQA2 HLA-DRA

5.08e-06167431978941
Pubmed

Identification of human CD4 residues affecting class II MHC versus HIV-1 gp120 binding.

HLA-DOA HLA-DQA2 HLA-DRA

5.08e-06167432543930
Pubmed

Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation.

HLA-DOA HLA-DQA2 HLA-DRA

5.08e-061674317959659
Pubmed

Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.

MSH6 ERCC3 PSME4 SLC25A1 ALDH18A1 IPO4

6.10e-0621174617314511
Pubmed

Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptors.

HLA-DOA HLA-DQA2 HLA-DRA

6.15e-061774315194762
Pubmed

The activity of Nef on HIV-1 infectivity.

HLA-DOA HLA-DQA2 HLA-DRA

6.15e-061774324904546
Pubmed

HIV-1 Nef promotes endocytosis of cell surface MHC class II molecules via a constitutive pathway.

HLA-DOA HLA-DQA2 HLA-DRA

7.37e-061874319620308
Pubmed

Reciprocal modulation of transcriptional activities between HIV-1 Tat and MHC class II transactivator CIITA.

HLA-DOA HLA-DQA2 HLA-DRA

7.37e-061874311118314
Pubmed

Tat competes with CIITA for the binding to P-TEFb and blocks the expression of MHC class II genes in HIV infection.

HLA-DOA HLA-DQA2 HLA-DRA

7.37e-061874310661406
Pubmed

A Large-scale genetic association study of esophageal adenocarcinoma risk.

CFLAR TGFBR1 LIG1 ABCC3 MSH6 ERCC3 CYP3A4

1.01e-0535174720453000
Pubmed

Nef performance in macrophages: the master orchestrator of viral persistence and spread.

HLA-DOA HLA-DQA2 HLA-DRA

1.03e-052074322103834
Pubmed

HIV gp120 inhibits T cell activation by interfering with expression of costimulatory molecules CD40 ligand and CD80 (B71).

HLA-DOA HLA-DQA2 HLA-DRA

1.03e-05207437541827
Pubmed

HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells.

HLA-DOA HLA-DQA2 HLA-DRA

1.03e-052074312427289
Pubmed

HIV-1 Gag-virus-like particles induce natural killer cell immune responses via activation and maturation of dendritic cells.

HLA-DOA HLA-DQA2 HLA-DRA

1.20e-052174321778700
Pubmed

HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41.

HLA-DOA HLA-DQA2 HLA-DRA

1.20e-05217438084338
Pubmed

Colinearity of novel genes in the class II regions of the MHC in mouse and human.

HLA-DOA HLA-DQA2 HLA-DRA

1.20e-05217431855816
Pubmed

cDNA sequence, map, and expression of the murine homolog of GTBP, a DNA mismatch repair gene.

MSH6 RIPK2

1.34e-0537428812455
Pubmed

Restoring multidrug resistance-associated protein 3 attenuates cell proliferation in the polycystic kidney.

ABCC3 PKD1

1.34e-05374225143454
Pubmed

The murine Ia alpha chains, E alpha and A alpha, show a surprising degree of sequence homology.

HLA-DQA2 HLA-DRA

1.34e-0537426300851
Pubmed

RICK, a novel protein kinase containing a caspase recruitment domain, interacts with CLARP and regulates CD95-mediated apoptosis.

CFLAR RIPK2

1.34e-0537429575181
Pubmed

The class II molecules of the human and murine major histocompatibility complex.

HLA-DQA2 HLA-DRA

1.34e-0537426198089
Pubmed

Life-span, T-cell responses, and incidence of lymphomas in congenic mice.

HLA-DQA2 HLA-DRA

1.34e-0537427732019
Pubmed

Single-Nucleotide Polymorphisms in NOD1, RIPK2, MICB, PLCE1, TNF, and IKBKE Genes Associated with Symptomatic Dengue in Children from Colombia.

IKBKE RIPK2

1.34e-05374230332343
Pubmed

PTEN identified as important risk factor of chronic obstructive pulmonary disease.

TGFBR1 LIG1 MSH6 ABCA1 ERCC3 OCA2 CDC25B

1.52e-0537474719625176
Pubmed

Role of HIV-1 Nef protein for virus replication in vitro.

HLA-DOA HLA-DQA2 HLA-DRA

1.59e-052374319770068
Pubmed

Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.

TGFBR1 LIG1 MSH6 ABCA1 ERCC3 OCA2 CDC25B

1.72e-0538174718676680
Pubmed

Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China.

TGFBR1 LIG1 MSH6 ABCA1 ERCC3 OCA2 CDC25B

1.75e-0538274719170196
Pubmed

Human immunodeficiency virus type-1 (HIV-1) Pr55gag virus-like particles are potent activators of human monocytes.

HLA-DOA HLA-DQA2 HLA-DRA

1.81e-052474318945465
Pubmed

Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation.

HLA-DOA HLA-DQA2 HLA-DRA

1.81e-052474315489916
Pubmed

Editorial. Nef: a notorious enigmatic factor in HIV biology.

HLA-DOA HLA-DQA2 HLA-DRA

1.81e-052474322175768
Pubmed

HIV accessory proteins and surviving the host cell.

HLA-DOA HLA-DQA2 HLA-DRA

2.06e-052574316091223
Pubmed

Adapters in lymphocyte signaling.

HLA-DOA HLA-DQA2 HLA-DRA

2.32e-052674311827988
Pubmed

Characterization of carbonic anhydrase IX interactome reveals proteins assisting its nuclear localization in hypoxic cells.

IPO5 SAAL1 IPO4

2.32e-052674323181366
Pubmed

Interactions of viral protein U (Vpu) with cellular factors.

HLA-DOA HLA-DQA2 HLA-DRA

2.61e-052774320012522
Pubmed

[The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway].

HLA-DOA HLA-DQA2 HLA-DRA

2.61e-052774312836198
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

MSH6 TBC1D4 RPAP1 RNF112 PKD1 NARS1 ALDH18A1 C6 DNAH14

2.63e-0573674929676528
Pubmed

Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis.

ABCA1 LIPE

2.67e-05474234461308
Pubmed

DNA repair and cell cycle control genes and the risk of young-onset lung cancer.

LIG1 MSH6

2.67e-05474217108146
Pubmed

Molecular analysis of the pathogenesis of autoimmune insulitis in NOD mice.

HLA-DQA2 HLA-DRA

2.67e-0547427809906
Pubmed

Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice.

HLA-DOA HLA-DQA2

2.67e-05474211069069
Pubmed

MHC characterization of ALR and ALS mice: respective similarities to the NOD and NON strains.

HLA-DQA2 HLA-DRA

2.67e-05474210369935
Pubmed

The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization.

HLA-DQA2 HLA-DRA

2.67e-05474247219
Pubmed

Analysis of MHC class II genes in the susceptibility to lupus in New Zealand mice.

HLA-DQA2 HLA-DRA

2.67e-05474210072504
Pubmed

Keeping the (kinase) party going: SLP-76 and ITK dance to the beat.

HLA-DOA HLA-DQA2 HLA-DRA

2.92e-052874317652306
Pubmed

One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.

HLA-DOA HLA-DQA2 HLA-DRA

2.92e-052874322103833
Pubmed

HIV/SIV escape from immune surveillance: focus on Nef.

HLA-DOA HLA-DQA2 HLA-DRA

3.25e-052974315078178
Pubmed

Modelling thymic HIV-1 Nef effects.

HLA-DOA HLA-DQA2 HLA-DRA

3.60e-053074316454711
Pubmed

Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.

HLA-DOA HLA-DQA2 HLA-DRA

3.98e-053174321922073
Pubmed

The mechanism of phospholipase C-gamma1 regulation.

HLA-DOA HLA-DQA2 HLA-DRA

3.98e-053174311048639
Pubmed

Immunoregulatory effects of HIV-1 Nef protein.

HLA-DOA HLA-DQA2 HLA-DRA

4.39e-053274319449444
Pubmed

Recognition Elements in the Histone H3 and H4 Tails for Seven Different Importins.

IPO5 IPO4

4.45e-05574227528606
Pubmed

Detection of a new cerebral malaria susceptibility locus, using CBA mice.

HLA-DQA2 HLA-DRA

4.45e-05574215536567
Pubmed

Immunochemical evidence for three Ia loci in the I-region of the H-2 complex.

HLA-DQA2 HLA-DRA

4.45e-05574272779
Pubmed

Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions.

HLA-DOA HLA-DQA2 HLA-DRA

4.82e-053374316354571
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

IPO5 SLC25A1 ALDH18A1 IPO4 RPL7A

6.50e-0519774531620119
Pubmed

Absence of MHC class II expression distinguishes fetal from adult B lymphopoiesis in mice.

HLA-DQA2 HLA-DRA

6.66e-0567428176204
Pubmed

Genome-wide association study of rheumatoid arthritis in the Spanish population: KLF12 as a risk locus for rheumatoid arthritis susceptibility.

HLA-DQA2 PTPRT

6.66e-05674218668548
Pubmed

New BAGE (B melanoma antigen) genes mapping to the juxtacentromeric regions of human chromosomes 13 and 21 have a cancer/testis expression profile.

BAGE2 BAGE3

6.66e-05674212461691
Pubmed

Association of polymorphisms of ABCA1 and ROS1 with hypertension in Japanese individuals.

ABCA1 CYP3A4

6.66e-05674218097620
Pubmed

Sequence of class II major histocompatibility complex genes from MRL mice. Conserved amino acids in the I-E beta chains from autoimmune mice.

HLA-DQA2 HLA-DRA

6.66e-0567421953819
Pubmed

Mice lacking all conventional MHC class II genes.

HLA-DQA2 HLA-DRA

6.66e-05674210468609
Pubmed

Mice lacking the MHC class II-associated invariant chain.

HLA-DQA2 HLA-DRA

6.66e-0567427679955
Pubmed

The NOD mouse: recessive diabetogenic gene in the major histocompatibility complex.

HLA-DQA2 HLA-DRA

6.66e-0567423003909
Pubmed

BAGE genes generated by juxtacentromeric reshuffling in the Hominidae lineage are under selective pressure.

BAGE2 BAGE3

6.66e-05674212676563
Pubmed

HLA-DO is a lysosomal resident which requires association with HLA-DM for efficient intracellular transport.

HLA-DOA HLA-DRA

6.66e-0567428890155
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

IPO5 MSH6 RNF112 FRYL IPO4

7.32e-0520274533005030
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO5 MSH6 NARS1 ALDH18A1 FRYL URB2 IPO4 RPL7A

7.50e-0565374822586326
Pubmed

Mapping the HLA-DO/HLA-DM complex by FRET and mutagenesis.

HLA-DOA HLA-DRA

9.31e-05774222733780
Pubmed

A molecular map of the immune response region from the major histocompatibility complex of the mouse.

HLA-DQA2 HLA-DRA

9.31e-0577426290895
Pubmed

Altered antigen presentation in mice lacking H2-O.

HLA-DOA HLA-DQA2

9.31e-0577429492004
Pubmed

The impact of H2-DM on humoral immune responses.

HLA-DQA2 HLA-DRA

9.31e-05774211714799
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PIKFYVE ABCC3 ARHGEF19 PSME4 GRTP1 RPAP1 PKD1 FBXL12 FRYL RALGAPA2

1.14e-041105741035748872
Pubmed

Genome-wide study reveals an important role of spontaneous autoimmunity, cardiomyocyte differentiation defect and anti-angiogenic activities in gender-specific gene expression in Keshan disease.

HLA-DOA HLA-DRA

1.24e-04874224384427
Pubmed

The diploid genome sequence of an individual human.

BAGE2 BAGE3

1.24e-04874217803354
Pubmed

Nod1, an Apaf-1-like activator of caspase-9 and nuclear factor-kappaB.

CFLAR RIPK2

1.24e-04874210329646
Pubmed

Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E.

IPO5 IPO4

1.24e-04874227114554
Pubmed

Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin.

CYP3A4 ALDH3A1

1.24e-04874218854779
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

LIG1 MSH6 RPAP1 SLC25A1 NARS1 URB2 IPO4 DHX29

1.26e-0470474829955894
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MSH6 ERCC3 TBC1D4 PSME4 SLC25A1 NARS1 ALDH18A1 URB2 IPO4 DHX29 RPL7A

1.31e-041353741129467282
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

SCYL2 IPO5 KIDINS220 NARS1 ALDH18A1 CRYBG3 DHX29 RPL7A

1.31e-0470874839231216
Pubmed

Strategies for inhibiting function of HIV-1 accessory proteins: a necessary route to AIDS therapy?

HLA-DOA HLA-DQA2 HLA-DRA

1.40e-044774319149577
Pubmed

Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.

TGFBR1 IKBKE RIPK2 FBXL12

1.55e-0412674424319055
GeneFamilyC1-set domain containing

HLA-DOA HLA-DQA2 HLA-DRA

2.25e-0442513591
GeneFamilyHistocompatibility complex|C1-set domain containing

HLA-DOA HLA-DQA2 HLA-DRA

2.58e-0444513588
GeneFamilyArmadillo repeat containing|Importins

IPO5 IPO4

1.16e-0318512596
GeneFamilyAldehyde dehydrogenases

ALDH18A1 ALDH3A1

1.29e-0319512398
GeneFamilyLipases|Arylacetamide deacetylase family

LIPE PNPLA3

1.74e-0322512464
GeneFamilyComplement system|Sushi domain containing

C6 ITGAM

4.62e-0336512492
CoexpressionAIZARANI_LIVER_C30_HEPATOCYTES_4

ABCC3 ABHD15 ABCA1 MAST4 GRTP1 CYP3A4 PNPLA3 C6 RALGAPA2 DHTKD1

3.85e-074467210M39129
CoexpressionGSE5589_LPS_VS_LPS_AND_IL10_STIM_IL6_KO_MACROPHAGE_45MIN_UP

PIKFYVE ABCC3 MYADM CRYBG3 RALGAPA2 ERMARD

1.88e-05200726M6618
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PIKFYVE SACS HLA-DOA HLA-DQA2 HLA-DRA CEMIP2

4.21e-07174736ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 CMIP MAST4 KIAA1755 FHIT PTPRT

6.23e-07186736b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial-Endothelial|Endothelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFLAR CMIP MAST4 HLA-DQA2 HLA-DRA CEMIP2

9.51e-072007362ae62c428728c1d9d4471d4be24bd6ab074fa22c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRA RIPK2 KIAA1755 ITGAM

1.63e-0652734d654e2b77c53ed5319015598b68a20bf4416380c
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OCA2 ITGAM VWA2 SLC7A11 PTPRT

3.32e-0613973527dd36f5ef03fa97f0fdb19fbd259cb60e7962b3
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OCA2 ITGAM VWA2 SLC7A11 PTPRT

3.32e-061397352a54627947f8c6597c041f4785f8a4e52d0edfba
ToppCellnormal_Lymph_Node-B_lymphocytes-Undetermined|normal_Lymph_Node / Location, Cell class and cell subclass

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA RPL7A

7.01e-0616273591ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C6 IPO4 SLC7A11 PTPRT CLHC1

7.22e-06163735360cd65decda24853124f33a174f5224d7f3ce23
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-Mes-like-AT1_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

C6 IPO4 SLC7A11 PTPRT CLHC1

7.22e-06163735b59d9b4f7c9f4e5e2c7783a49a96729dae3a81e5
ToppCellNS-critical-d_0-4-Myeloid-Resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA RPL7A

7.67e-061657356b1c29dcef5a945786806ddbddddcec0023bd66e
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage|368C / Donor, Lineage, Cell class and subclass (all cells)

ABCC3 HLA-DOA HLA-DQA2 HLA-DRA ITGAM

9.64e-06173735bba8265a58f8f5659dc7b9da2fe27b15033fce34
ToppCellSevere-Myeloid-mDC|Severe / Condition, Lineage, Cell class and cell subclass

TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA SLC7A11

1.20e-0518173500f2949b609ac21bd2da6fd8f685739eeb2f48ad
ToppCellSevere-Myeloid-mDC-|Severe / Condition, Lineage, Cell class and cell subclass

TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA SLC7A11

1.20e-0518173551ded98c76ec35ab1d24ac3ab98280381daa9831
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA CEMIP2

1.37e-05186735d7d884ff4184636081c350d29f797bd923c6a3b4
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR1 TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA

1.44e-051887359fc3819aae5a2b2534cb131d467435b5cfc420d6
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TGFBR1 TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA

1.44e-051887355e5d779ea079d3b2a1ef650b06b9f5cc1ffef5e7
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 ABCC3 MYADM ABCA1 ITGAM

1.48e-051897356dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 ABCC3 MYADM ABCA1 ITGAM

1.48e-051897353ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCellfacs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 ABCC3 MYADM ABCA1 ITGAM

1.48e-05189735875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCellfacs-Brain_Myeloid-Striatum-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFBR1 ABCC3 MYADM ABCA1 ITGAM

1.48e-0518973597ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCellILEUM-inflamed-(2)_B_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA RPL7A

1.56e-051917350aa913678456b7d525bd177588f2463f6ed76cd7
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_memory|lymph-node_spleen / Manually curated celltypes from each tissue

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA PTPRT

1.68e-05194735b57ae94a092b58623a244a258b4659a3864542c7
ToppCell390C-Myeloid-Dendritic-cDC2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CFLAR HLA-DOA HLA-DQA2 HLA-DRA RIPK2

1.76e-05196735799f54131fb1034f82ef4872cfb2c64359541086
ToppCellMild/Remission-B_naive-2|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYADM HLA-DQA2 HLA-DRA RPL7A CEMIP2

1.80e-051977350042716ba630e4d5142cca46fcb279a2e64370f2
ToppCellCOVID-19_Convalescent-Classical_Monocyte-cMono_2|COVID-19_Convalescent / Disease condition and Cell class

HIPK3 MYADM CMIP HLA-DRA ITGAM

1.85e-05198735f65fd9b773aeafa55e38309479954a8e41371f52
ToppCellMild/Remission-B_naive-2|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYADM HLA-DQA2 HLA-DRA RPL7A CEMIP2

1.85e-05198735d238ad320e1989da01c48587f79eaeaa469cfa28
ToppCellnormal_Lung-Myeloid_cells-CD1c+_DCs|normal_Lung / Location, Cell class and cell subclass

CFLAR HLA-DOA HLA-DQA2 HLA-DRA RIPK2

1.85e-0519873585d9bf50a1a5adaab52bab88317acd870d1704d6
ToppCellTCGA-Colorectal-Primary_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

RIPK2 PRSS22 URB2 CDC25B VWA2

1.89e-05199735c7d6a8398f2419b726a0461585d1ee0561654e3b
ToppCell(4)_Endothelial_cells-(4)_Blood_vessel|(4)_Endothelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

HIPK3 CFLAR CMIP MAST4 HLA-DRA

1.89e-05199735e24d70e79f25cdd3300bf5e2322713355264d4c5
ToppCellEndothelial_cells-Endothelial-A|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id

CFLAR CMIP MAST4 HLA-DRA CEMIP2

1.89e-051997352a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCelltumor_Lung-Myeloid_cells-CD1c+_DCs|tumor_Lung / Location, Cell class and cell subclass

CFLAR HLA-DOA HLA-DQA2 HLA-DRA RIPK2

1.89e-05199735de65f2f41a507ae98d27c37aedac7fdbf2d3c697
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

RIPK2 PRSS22 URB2 CDC25B VWA2

1.89e-0519973585b3b1ad01368dae4adbc9da7efc148e49992f69
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MAST4 KIAA1755 SLC7A11 SLC38A3 CEMIP2

1.94e-05200735032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellLPS_only-Endothelial-Endothelial-Activated_Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

CFLAR MAST4 RIPK2 RALGAPA2 CEMIP2

1.94e-05200735edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MAST4 KIAA1755 SLC7A11 SLC38A3 CEMIP2

1.94e-0520073568fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MAST4 KIAA1755 SLC7A11 SLC38A3 CEMIP2

1.94e-05200735376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MAST4 KIAA1755 SLC7A11 SLC38A3 CEMIP2

1.94e-052007357fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MAST4 KIAA1755 SLC7A11 SLC38A3 CEMIP2

1.94e-05200735878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

MAST4 KIAA1755 SLC7A11 SLC38A3 CEMIP2

1.94e-052007357136936d05ab344a560cf159684c881063b5430d
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PIKFYVE HLA-DOA HLA-DRA C6

7.19e-051357347743a01dc9c4542e910e7c0fe046004692a680bf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col18a1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PRSS22 BPIFB4 OCA2 DNAH14

1.03e-04148734fc80c02b51cf55a04ce550838ee2f41d8f656f41
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_macrophage-Langerhans_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TBC1D4 HLA-DQA2 BAGE2 SLC7A11

1.29e-0415773410341ed8cbee0f636770a82cf580f6453bee8596
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_4|368C / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DQA2 HLA-DRA ITGAM

1.32e-04158734f9cfb110342be3c91aba9914805332f22ba89101
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SACS HLA-DOA BPIFB4 SLC7A11

1.39e-041607348dae9b0cf90a09acb196223f45a14680102630b2
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ABHD15 HLA-DOA ALDH3A1 SLC7A11

1.39e-0416073461f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

ABHD15 HLA-DOA ALDH3A1 SLC7A11

1.39e-0416073434b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBC1D4 MAST4 CDC25B DDC

1.42e-04161734b24293fdae9637983fcf4f2d4659a3554e00a53f
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg-Treg_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TBC1D4 MAST4 CDC25B DDC

1.42e-04161734eddcbe266d4a84a340fa8f2128d2b7e293968dca
ToppCelllymphoid-NK_cell-TNFRSF18+IL7R-_NK_cell|NK_cell / Lineage, cell class and subclass

MYADM PRSS22 FHIT CDC25B

1.45e-041627349c58ce6643d3a00f09dc89f94e5ccf8f470694b2
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_naive|bone_marrow / Manually curated celltypes from each tissue

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

1.45e-0416273444832055b11a789e320c802aadb345e065defc8f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal-GABAergic_neurons|GW16 / Sample Type, Dataset, Time_group, and Cell type.

CRYBG3 VWA2 PTPRT CEMIP2

1.52e-041647344d7b2d0980fb4f47721fa2891151e2bd892ccb91
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCC3 ARHGEF19 PNPLA3 VWA2

1.52e-04164734ea02ca343b2b28e437304de889e2ae1e315a1197
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA

1.60e-04166734d373f1092e85eeb317a7406032b259f11e6adbe0
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TBC1D4 HLA-DOA HLA-DQA2 HLA-DRA

1.60e-04166734f453a1d545d59003d98485ac31e85e6cf451817c
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-cDC2|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SACS HLA-DOA HLA-DRA ITGAM

1.63e-041677341bd0aa7a3c8649f342bb856cf861c4c5984ad889
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-myeloid-myeloid_dendritic|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DOA HLA-DQA2 HLA-DRA SLC7A11

1.63e-04167734ecdbfde870a2a44c44b9dd65a8737afc6fbf816c
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PNPLA3 VWA2 SLC38A3

1.63e-0416773440d102e01ccbc7262d00fafd59ca5234909009cb
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRSS22 PNPLA3 SLC38A3 PTPRT

1.67e-041687348072d0496b7b730c4601009eaa69ec5366d26d73
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

1.67e-04168734494d5a11154ff22fedb25f4036d730cef376da60
ToppCelldroplet-Kidney-nan-21m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 VWA2 DDC SLC38A3

1.79e-04171734007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCellCOVID_vent-Lymphocytic-Dendritic-pDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

ABHD15 HLA-DOA HLA-DRA DHTKD1

1.79e-04171734779c951d274ecbd1d546ac425d6c8e718623be5a
ToppCellCOVID_vent-Lymphocytic-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

ABHD15 HLA-DOA HLA-DRA DHTKD1

1.79e-04171734debbb071d260639b16269c94d172766908325c58
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS22 ALDH3A1 SLC7A11 SLC38A3

1.79e-041717348ed98f223143bd81d9819e9a420eb9cc81ee6c53
ToppCellfacs-Lung-24m-Epithelial-airway_epithelial-club_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS22 ALDH3A1 SLC7A11 SLC38A3

1.79e-04171734bd339e482f09a3fa04b086029b94f45205b8a6c5
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MYADM CMIP HLA-DQA2 HLA-DRA

1.87e-04173734694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellTCGA-Adrenal-Primary_Tumor-Adrenocortical_carcinoma-Usual_Type-4|TCGA-Adrenal / Sample_Type by Project: Shred V9

MSH6 LIPE MC2R IPO4

1.91e-0417473415e2b9f46404ff9575e149024b24cb17b50b02b5
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD15 MAST4 FRYL PTPRT

1.91e-04174734f1fe1f4216748a9562dd03bd48c70b23c7ff4d1d
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Myeloid-microglial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ABHD15 HLA-DOA ITGAM

1.91e-041747348d6df5938cef542f23259ce471eea1a1afbed03c
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ABHD15 HLA-DOA ITGAM

1.91e-041747342af54c3427aacfa232e2aca6003b4a8ecb8bba66
ToppCell5'-Adult-LargeIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBC1D4 HLA-DOA HLA-DRA SLC7A11

1.91e-0417473416204ff504b7b382b4d90ca35003ad5336020e07
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 ABHD15 HLA-DOA ITGAM

1.91e-04174734eca643b8f5b92aeed5a77c94b4301fd8100f9401
ToppCellfacs-BAT|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DOA PRSS22 ALDH3A1 SLC7A11

1.95e-0417573446d6e319f8ca46592f23257800bcb6d228fffbbe
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D4 HLA-DOA HLA-DRA SLC7A11

2.04e-04177734aa56129d2d5a73a10e33b7162233a4d9337ee535
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D4 HLA-DOA HLA-DRA SLC7A11

2.04e-04177734d78a6003ce2d15d7771ae385de252eec7e3c3eea
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D4 HLA-DOA HLA-DRA SLC7A11

2.04e-0417773470ca5b6fde2e38af1eb88a7d6e8746edba298191
ToppCellNS-critical-d_07-13-Lymphoid-B_cell|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

2.04e-04177734d4db058c09012ec9fbde61277a9f86d9956de8fc
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARHGEF19 GRTP1 CDC25B PTPRT

2.08e-04178734c77a1d1a9aef0ab51b4408b9e84f201219788ca2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MAST4 KIAA1755 PTPRT

2.13e-04179734d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.4.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABHD15 HLA-DQA2 HLA-DRA PNPLA3

2.17e-04180734fb8bc639f7f94e7aed9f9d708d5d5c78178533ae
ToppCellnormal_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

MYADM HLA-DQA2 HLA-DRA CEMIP2

2.27e-041827340ef8fb13488a65717b050b1b4e4bf062a1553eff
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 RNF112 KIAA1755 CRYBG3

2.32e-041837345377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell367C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DQA2 HLA-DRA ITGAM

2.32e-04183734b12b89debc9dd6396188bc8fe44f54c01c560966
ToppCell367C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DQA2 HLA-DRA ITGAM

2.32e-0418373419cc0009f5332b6e4d4274df123eebbfc80b669a
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

HLA-DOA HLA-DQA2 HLA-DRA ALDH3A1

2.36e-04184734ee295f6fa898da53883e1358b17f2c2dd177e9a7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCC3 MAST4 KIAA1755 PNPLA3

2.36e-041847349434731f651820b05335085582960f08fbf895de
ToppCellpdx-Tumor_cells-T0|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ABCA1 CMIP KIAA1755 FHIT

2.41e-041857341d874608aa2062024323512f68889219471b2f00
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Lymphoid_DC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFLAR TBC1D4 HLA-DRA SLC7A11

2.41e-0418573448de4d9fad55077732bf64eca4919103ecbc1512
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D4 MAST4 FHIT DNAH14

2.41e-04185734898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HIPK3 IKBKE PKD1 ITGAM

2.46e-0418673474c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DOA HLA-DQA2 HLA-DRA SLC7A11

2.46e-041867340c55248b4a9f9bcc32a7e94329aea80796fd4a38
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DOA HLA-DQA2 HLA-DRA SLC7A11

2.46e-041867345d1d77825b85f80de20d7b91418820c6dbdab84a
ToppCell3'-Distal_airway-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HLA-DOA HLA-DQA2 HLA-DRA SLC7A11

2.46e-0418673461b5300f2d9b02e4c850642e4cae3648af46772f
ToppCellhealthy_donor-Lymphocytic-Dendritic|healthy_donor / Disease condition, Lineage, Cell class and subclass

ABHD15 TBC1D4 HLA-DRA SLC7A11

2.46e-04186734916f2aeea4989ba7a29e071e348a51010f010223
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

MSH6 KIDINS220 FRYL SLC7A11

2.46e-041867348571956890fc9894d766ba294a28e376b4aba428
ToppCell10x5'-Liver-Myeloid_Dendritic-DC1|Liver / Manually curated celltypes from each tissue

HLA-DOA HLA-DQA2 HLA-DRA CRYBG3

2.46e-04186734e823529ffd06352c6bdec102f221fdf27f7c7369
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CMIP MAST4 PNPLA3 FHIT

2.46e-041867345784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellhealthy_donor-Lymphocytic-Dendritic-pDC|healthy_donor / Disease condition, Lineage, Cell class and subclass

ABHD15 TBC1D4 HLA-DRA SLC7A11

2.46e-0418673445f66619e45d590c7365a51782d4ac46b7d31fde
ToppCelllymphoid-B_cell-Naive_B_cell|World / Lineage, cell class and subclass

PIKFYVE HLA-DOA HLA-DQA2 HLA-DRA

2.51e-04187734904ffd8cf4513e86fcd4c2b7faf24a34fbd2dce3
ToppCellSmart-seq2-blood_(Smart-seq2)-lymphocytic-B_lymphocytic-naive_B_cell|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA1 HLA-DOA HLA-DQA2 HLA-DRA

2.51e-04187734160e5f338537d90d50f863a1be801b1071ac7da7
ToppCellfacs-Bladder|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCC3 PRSS22 ALDH3A1 SLC7A11

2.51e-04187734dd5ca59417fd1b388fd975f0f3e1f3245d66ebc5
Drugnaphthalene acetic acid

ABCA1 KIDINS220 RNF112 FHIT CDC25B DDC

1.74e-0778726CID000006862
Diseaselymphocyte count

SAAL1 CMIP PSME4 HLA-DOA CYP3A4 IKBKE HLA-DRA ALDH18A1 WDR27 VWA2 DDC PTPRT CLHC1

3.01e-0514646913EFO_0004587
DiseaseColorectal Carcinoma

TGFBR1 LIG1 ABCC3 MSH6 ABCA1 RPAP1 SACS VWA2 PTPRT

3.68e-05702699C0009402
DiseaseAdenocarcinoma of lung (disorder)

SCYL2 IPO5 MSH6 ALDH18A1 IPO4

1.24e-04206695C0152013
Diseasesusceptibility to hepatitis B infection measurement

HLA-DOA HLA-DRA PTPRT

4.60e-0464693EFO_0008405
Diseaseinherited metabolic disorder (is_implicated_in)

LIG1 DDC

5.55e-0415692DOID:655 (is_implicated_in)
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

ABCA1 CMIP HLA-DRA

5.74e-0469693EFO_0007788, EFO_0008002
Diseaseurate measurement, bone density

SCYL2 KIDINS220 MAST4 KIAA1755 FHIT SLC38A3 DNAH14

6.05e-04619697EFO_0003923, EFO_0004531
Diseasesquamous cell carcinoma (is_implicated_in)

OCA2 FHIT

8.05e-0418692DOID:1749 (is_implicated_in)
Diseasekidney disease (biomarker_via_orthology)

TGFBR1 ABCC3

1.10e-0321692DOID:557 (biomarker_via_orthology)
Diseasechronic hepatitis B virus infection

HLA-DOA HLA-DQA2

1.44e-0324692EFO_0004239
DiseaseLynch syndrome (is_implicated_in)

TGFBR1 MSH6

1.44e-0324692DOID:3883 (is_implicated_in)
Diseasechylomicron measurement, triglyceride measurement, very low density lipoprotein cholesterol measurement

CMIP HLA-DRA PNPLA3

1.50e-0396693EFO_0004530, EFO_0008317, EFO_0008596
Diseasediet measurement, bilirubin measurement

SLC38A3 PTPRT

1.69e-0326692EFO_0004570, EFO_0008111
Diseaseeye morphology measurement

KIAA1755 WDR27 SLC38A3 PTPRT

1.72e-03218694EFO_0007858
Diseasetriglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement

ABCA1 CMIP PNPLA3 ITGAM

1.93e-03225694EFO_0008317, EFO_0020947
DiseaseBMI-adjusted waist-hip ratio, sex interaction measurement, age at assessment

ABCA1 CMIP HLA-DRA

1.93e-03105693EFO_0007788, EFO_0008007, EFO_0008343
DiseaseOral ulcer

HLA-DQA2 HLA-DRA RIPK2

2.04e-03107693HP_0000155

Protein segments in the cluster

PeptideGeneStartEntry
VPRLFEEVLGVICRP

URB2

466

Q14146
RVLKDCSIPEIELFP

CRYBG3

2381

Q68DQ2
RVLADVLPDLLCPIV

BPIFB4

321

P59827
VLPDLLCPIVDVVLG

BPIFB4

326

P59827
FGPVLPIVCVRSLEE

ALDH3A1

336

P30838
VFVCIALVFSLIVPP

ABCA1

1356

O95477
PRVLPNLVAVCLAAI

CMIP

321

Q8IY22
VPDIVRCVPPFREIA

TENT2

126

Q6PIY7
AIIRVEELCPFPLDS

DHTKD1

831

Q96HY7
SVPEILRVPLEELCL

DHX29

1006

Q7Z478
PRFEICVEVILGLVC

DDC

396

P20711
LLFLCRDVAIDVVPP

CFLAR

21

O15519
PLRDVDEAAVPVLCI

ABHD15

341

Q6UXT9
PVTIRLCEVLNLDPR

OCA2

451

Q04671
VLSALILACFREKPP

ABCC3

181

O15438
VCLDLFPVAPEELRA

ARHGEF19

46

Q8IW93
LICLVDNIFPPVVNI

HLA-DQA2

131

P01906
TPVLVARDVKVFLPC

KIDINS220

1036

Q9ULH0
PLCLRDEVVVHLAPL

KIAA1755

81

Q5JYT7
GLPEDEFLVVLRCVV

IKBKE

106

Q14164
ICVALVVLPLQFEEL

KCNT1

316

Q5JUK3
IQFSERVLPICLPDA

PRSS22

151

Q9GZN4
FPFLIPILEVLNICV

CYP3A4

226

P08684
PILEVLNICVFPREV

CYP3A4

231

P08684
LTRAVCVVFPVPFLI

OR51H1

151

Q8NH63
FVPPDLKVLGEICLR

PNPLA3

226

Q9NST1
LFRTCIAAIPRLIPD

FRYL

556

O94915
PIAPCSLDKRVILIF

CDC25B

471

P30305
IILIVELCGLQARFP

MYADM

81

Q96S97
RPFCTEALPLLVRVI

IPO5

941

O00410
PAEVCRLTPIDRVFT

MSH6

1161

P52701
NIFLLEPCAEVPVLL

RALGAPA2

521

Q2PPJ7
RAPEIILGLPFCEAI

HIPK3

366

Q9H422
LLVIFESRPDCLPQV

ALDH18A1

476

P54886
VLPLDRCLPFLISVD

PTPRT

1211

O14522
CIIILVLQEPTPFRI

BAGE3

61

Q86Y29
DVILCISPVITFREP

PIKFYVE

1051

Q9Y2I7
VLVCPLRPVERFHDL

FHIT

36

P49789
LICIVDNIFPPVINI

HLA-DOA

131

P06340
ELAPIVDLVRNIPCA

C6

486

P13671
CLFVDILPVETVLRI

GRTP1

236

Q5TC63
LLLVVDPCSVPFRLT

CEMIP2

1246

Q9UHN6
PVELREPNVLICFID

HLA-DRA

121

P01903
APIFEVNLCLRIPAE

DNAH14

531

Q0VDD8
IARPARLLECLEFDP

MAST4

476

O15021
PTLFCPRIVLEVLVV

ERMARD

521

Q5T6L9
AQDFLVAIAEPVCRP

ERCC3

96

P19447
CIIILVLQEPTAFRI

BAGE2

61

Q86Y30
TFCEVPDLDRIIPVL

LIG1

506

P18858
ESEEQPVFRLVPCIL

SAAL1

236

Q96ER3
PVFRLVPCILEAAKQ

SAAL1

241

Q96ER3
IPFLCPERAPAEFIR

SACS

3651

Q9NZJ4
VIDVAPELLRICSLI

IPO4

1016

Q8TEX9
VQALLLPDAPLVCVR

IRGQ

316

Q8WZA9
ELCVERIRLVLTPPA

LIPE

1041

Q05469
VFVLEVLRVEPAACI

PKD1

1291

P98161
VIPQFFCDVPSLLRI

OR14A2

171

Q96R54
RDPDPLNICVFILLL

RTP4

221

Q96DX8
PFDVLILCVRVAVLT

SLC38A3

361

Q99624
INEPILLCRFPVEIK

NARS1

431

O43776
VDPIELVVFLPALCR

RPL7A

161

P62424
DPTVLPLLECIVLDR

FBXL12

146

Q9NXK8
PLLECIVLDRVPAFR

FBXL12

151

Q9NXK8
VPFVLPNVLLIAEEC

SCYL2

386

Q6P3W7
CIEDPVSPIVLRLNF

ITGAM

721

P11215
CIAEIDLIPRDRPFV

TGFBR1

71

P36897
CPRVVLPEEIFFTIS

MC2R

21

Q01718
VLPPIICRSDKEFLE

CLHC1

11

Q8NHS4
LEPFFIQCEIPELAI

SLC7A11

151

Q9UPY5
LQETCPVRAEPLLLV

RNF112

126

Q9ULX5
PSFLKCLIELEPVLR

RIPK2

281

O43353
LLEAVCVFLFSRVPP

VWA2

6

Q5GFL6
PRLGRVCLDVAIVFV

SLC25A1

281

P53007
CPRLIETIVREFLPT

RPAP1

586

Q9BWH6
CRDIIPLVLEFLRPD

PSME4

1001

Q14997
EVILVLSAPFLRCVP

TBC1D4

81

O60343
EQVEVTFPVLRLAPC

WDR27

286

A2RRH5
LPELVRAKIPFSACL

USP13

531

Q92995