Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionisomerase activity

RANBP2 ACADM ZGRF1 CFTR RGPD1 QSOX1 PGM2

6.59e-051921047GO:0016853
GeneOntologyMolecularFunctionSUMO ligase activity

RANBP2 RGPD1 CBX4

1.47e-04201043GO:0061665
GeneOntologyBiologicalProcessRNA transport

RANBP2 PEG10 RGPD1 POM121L2 NCBP1 NUP210 AGFG1 SENP2

2.36e-061751018GO:0050658
GeneOntologyBiologicalProcessnucleic acid transport

RANBP2 PEG10 RGPD1 POM121L2 NCBP1 NUP210 AGFG1 SENP2

2.36e-061751018GO:0050657
GeneOntologyBiologicalProcessestablishment of RNA localization

RANBP2 PEG10 RGPD1 POM121L2 NCBP1 NUP210 AGFG1 SENP2

2.68e-061781018GO:0051236
GeneOntologyBiologicalProcessmRNA transport

RANBP2 PEG10 RGPD1 NCBP1 NUP210 AGFG1 SENP2

7.27e-061451017GO:0051028
GeneOntologyBiologicalProcessglucan metabolic process

NPC1 MGAM ACADM PCDH12 PGM2 IL6ST

1.03e-051011016GO:0044042
GeneOntologyBiologicalProcessRNA localization

RANBP2 PEG10 RGPD1 POM121L2 NCBP1 NUP210 AGFG1 SENP2

1.15e-052171018GO:0006403
GeneOntologyBiologicalProcessnucleobase-containing compound transport

RANBP2 PEG10 RGPD1 POM121L2 NCBP1 NUP210 AGFG1 SENP2

3.10e-052491018GO:0015931
GeneOntologyBiologicalProcesspolysaccharide metabolic process

NPC1 MGAM ACADM PCDH12 PGM2 IL6ST

3.64e-051261016GO:0005976
GeneOntologyBiologicalProcesscell recognition

CNTN4 ZAN PCDH12 LGALS3 NRP1 CD36 CNR1

5.42e-051981017GO:0008037
GeneOntologyBiologicalProcessaxoneme assembly

DRC7 CFAP43 DNAH1 DNAH17 CFAP74

1.99e-041091015GO:0035082
GeneOntologyBiologicalProcessneuron recognition

CNTN4 PCDH12 NRP1 CNR1

2.00e-04591014GO:0008038
GeneOntologyCellularComponentnuclear pore

RANBP2 RGPD1 POM121L2 NUP210 AGFG1 SENP2

1.20e-051011056GO:0005643
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

RANBP2 ACADM GARS1 NCBP1 BCS1L VIRMA ARCN1 G3BP1 DDX18 ALDH18A1 GFM1 HDLBP

4.36e-076071081239147351
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

BRIX1 FLNB GARS1 NCBP1 PRDX2 VIRMA ARCN1 KIAA1671 PSIP1 G3BP1 TRIM56 DDX18 NUP210 ALDH18A1 HDLBP

8.12e-0612571081536526897
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNB GARS1 NCBP1 PRDX2 ARCN1 LGALS3 DNAH1 PSIP1 DDX18 ALDH18A1 PGM2 HDLBP

8.18e-068071081230575818
Pubmed

Concerted action of CB1 cannabinoid receptor and deleted in colorectal cancer in axon guidance.

DCC CNR1

9.55e-062108221273433
Pubmed

Mechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BKCa channels.

CFTR KCNMA1

9.55e-062108228474046
Pubmed

Adrenaline-induced colonic K+ secretion is mediated by KCa1.1 (BK) channels.

CFTR KCNMA1

9.55e-062108220351045
Pubmed

Neuropilin is a receptor for the axonal chemorepellent Semaphorin III.

SEMA4B NRP1

9.55e-06210829288753
Pubmed

CMT2D neuropathy is linked to the neomorphic binding activity of glycyl-tRNA synthetase.

GARS1 DCC NRP1

1.29e-0515108326503042
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RANBP2 RGPD1 NUP210

1.29e-0515108314697343
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

CNTN4 SEMA4B ICAM2 LAMA2 NRP1 QSOX1 IL6ST

1.64e-05257108716335952
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

BRIX1 FLNB RANBP2 NCBP1 ARCN1 NRP1 KIAA1671 PSIP1 G3BP1 SACS DDX18 NUP210 HDLBP

1.80e-0510241081324711643
Pubmed

HIV DNA integration.

RANBP2 PSIP1

2.86e-053108222762018
Pubmed

Galectin-3 alleviates demyelination by modulating microglial anti-inflammatory polarization through PPARγ-CD36 axis.

LGALS3 CD36

2.86e-053108238986827
Pubmed

A Pseudomonas aeruginosa toxin that hijacks the host ubiquitin proteolytic system.

CFTR G3BP1

2.86e-053108221455491
Pubmed

Cannabinoid receptor CB2 modulates axon guidance.

DCC CNR1

2.86e-053108223951024
Pubmed

Secretory Galectin-3 promotes hepatic steatosis via regulation of the PPARγ/CD36 signaling pathway.

LGALS3 CD36

2.86e-053108233991615
Pubmed

Potent pro-inflammatory and pro-fibrotic molecules, osteopontin and galectin-3, are not major disease modulators of laminin α2 chain-deficient muscular dystrophy.

LAMA2 LGALS3

2.86e-053108228281577
Pubmed

A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.

CNTN4 DCC

2.86e-053108222318345
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

BRIX1 FLNB RANBP2 ACADM STK26 NCBP1 ARCN1 G3BP1 DDX18 NUP210

3.11e-056381081033239621
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RANBP2 STK26 GARS1 NCBP1 PRDX2 SYT7 ARCN1 LGALS3 DNAH1 G3BP1 WDR87 DDX18 ALDH18A1 HDLBP

3.26e-0512471081427684187
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BRIX1 FLNB RANBP2 NCBP1 VIRMA G3BP1 DDX18 NUP210 ALDH18A1 HDLBP

3.78e-056531081022586326
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RANBP2 RGPD1 SENP2

4.30e-0522108327717094
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

FLNB SEMA4B ACADM BMP2K GARS1 CBX4 VARS2 PRDX2 BCS1L ARCN1 NRP1 TMTC3 ALDH18A1 GFM1 HDLBP

4.30e-0514511081530550785
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

BRIX1 FLNB PEG10 NCBP1 VIRMA PCDH20 PSIP1 G3BP1 TRIM56 DDX18 HDLBP

4.39e-058071081122681889
Pubmed

Netrin 1 regulates ventral tangential migration of guidepost neurons in the lateral olfactory tract.

DCC NRP1

5.71e-054108216439477
Pubmed

Molecular mechanisms of retroviral integration site selection.

RANBP2 PSIP1

5.71e-054108225147212
Pubmed

Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules.

GARS1 G3BP1

5.71e-054108236738734
Pubmed

Knockdown of LI-cadherin alters expression of matrix metalloproteinase-2 and -9 and galectin-3.

LGALS3 CDH17

5.71e-054108227035870
Pubmed

Docking of HIV-1 Vpr to the nuclear envelope is mediated by the interaction with the nucleoporin hCG1.

RANBP2 PSIP1 NUP210

7.19e-0526108312228227
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

NPC1 RANBP2 RGPD1 PRDX2 LGALS3 ALDH18A1

7.76e-05226108637839992
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

FLNB GARS1 ARCN1 PSIP1 G3BP1 GFM1 HDLBP

8.61e-05334108730425250
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

BRIX1 PEG10 GARS1 NCBP1 VARS2 VIRMA ARCN1 NRP1 PSIP1 G3BP1 TRIM56 DDX18 ALDH18A1 HDLBP

9.01e-0513711081436244648
Pubmed

Viral delivery of L1CAM promotes axonal extensions by embryonic cerebral grafts in mouse brain.

DCC NRP1

9.50e-055108236963389
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

BRIX1 FLNB RANBP2 PSIP1 NUP210 ALDH18A1 RPRD2

9.61e-05340108729478914
Pubmed

Polymorphisms in genes involved in neurodevelopment may be associated with altered brain morphology in schizophrenia: preliminary evidence.

FLNB PCDH12 NRP1

1.11e-0430108319054571
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

FLNB RANBP2 HECW1 HECTD4 NUP210 SLFN11

1.35e-04250108633536335
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

BRIX1 FLNB RANBP2 GARS1 NCBP1 PRDX2 ARCN1 PSIP1 G3BP1 DDX18 NUP210 ALDH18A1 GFM1 HDLBP

1.35e-0414251081430948266
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

NPC1 BRIX1 FLNB RANBP2 PRDX2 G3BP1 ALDH18A1 GFM1

1.39e-04484108831995728
Pubmed

UBXN3B positively regulates STING-mediated antiviral immune responses.

IFNAR1 TRIM56

1.42e-046108229899553
Pubmed

G3BP1 inhibits ubiquitinated protein aggregations induced by p62 and USP10.

CFTR G3BP1

1.42e-046108231501480
Pubmed

CD36 participates in a signaling pathway that regulates ROS formation in murine VSMCs.

PRDX2 CD36

1.42e-046108220978343
Pubmed

The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection.

IFNAR1 CD36

1.42e-046108225419628
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

FLNB RANBP2 ACADM BMP2K NCBP1 ARCN1 LGALS3 KIAA1671 ARFGEF3 PSIP1 G3BP1 NUP210 BUB1B ALDH18A1

1.50e-0414401081430833792
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CNTN4 SEMA4B HECW1 VARS2 VPS13D SACS DNAH17 NUP210

1.57e-04493108815368895
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RANBP2 PRDX2 ARCN1 KIAA1671 PSIP1 G3BP1 BUB1B AGFG1 RPRD2 SLFN11 HDLBP

1.60e-049341081133916271
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

FLNB RANBP2 CFTR GARS1 RGPD1 NCBP1 PRDX2 ARCN1 NUP210

1.93e-04647108926618866
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RANBP2 RGPD1

1.99e-04710829037092
Pubmed

PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice.

DCC NRP1

1.99e-047108231430342
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RANBP2 RGPD1

1.99e-047108211353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RANBP2 RGPD1

1.99e-047108230944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RANBP2 RGPD1

1.99e-047108238838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RANBP2 RGPD1

1.99e-04710827559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RANBP2 RGPD1

1.99e-047108217372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RANBP2 RGPD1

1.99e-047108238657106
Pubmed

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

RANBP2 PSIP1

1.99e-047108224051001
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RANBP2 RGPD1

1.99e-047108221205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RANBP2 RGPD1

1.99e-047108218949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RANBP2 RGPD1

1.99e-047108225187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RANBP2 RGPD1

1.99e-04710828603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RANBP2 RGPD1

1.99e-047108226632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RANBP2 RGPD1

1.99e-047108224403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RANBP2 RGPD1

1.99e-047108223818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RANBP2 RGPD1

1.99e-047108223536549
Pubmed

Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.

RANBP2 SENP2

1.99e-047108212192048
Pubmed

Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.

IFNAR1 SLFN11

1.99e-047108215351786
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RANBP2 RGPD1

1.99e-047108212191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RANBP2 RGPD1

1.99e-047108222821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RANBP2 RGPD1

1.99e-047108220682751
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RANBP2 RGPD1 NUP210

2.27e-0438108312791264
Pubmed

DEAD-box helicase DDX27 regulates 3' end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex.

BRIX1 G3BP1 DDX18

2.45e-0439108325825154
Pubmed

A long non-coding RNA specifically expressed in early embryos programs the metabolic balance in adult mice.

ACADM CD36 UCP1

2.45e-0439108333059001
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

CNTN4 FLNB NCBP1 DCC LGALS3 G3BP1 DDX18 PAXIP1 SLFN11

2.49e-04670108922990118
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RANBP2 RGPD1

2.64e-048108221670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RANBP2 RGPD1

2.64e-048108227412403
Pubmed

CFAP43 modulates ciliary beating in mouse and Xenopus.

CFAP43 DNAH1

2.64e-048108231884020
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RANBP2 RGPD1

2.64e-048108221310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RANBP2 RGPD1

2.64e-048108222262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RANBP2 RGPD1

2.64e-048108228745977
Pubmed

Coordinated functions of Netrin-1 and Class 3 secreted Semaphorins in the guidance of reciprocal septohippocampal connections.

DCC NRP1

2.64e-048108215121176
Pubmed

Semaphorin 4B interacts with the post-synaptic density protein PSD-95/SAP90 and is recruited to synapses through a C-terminal PDZ-binding motif.

SEMA4B NRP1

2.64e-048108215978582
Pubmed

Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.

TMEM94 TTLL4 HMGXB3

2.85e-044110838724849
Pubmed

ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.

FLNB COL11A2 PHACTR4

3.06e-0442108329107558
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

NPC1 DPAGT1 FLNB RANBP2 GARS1 NCBP1 PRDX2 ARCN1 LGALS3 G3BP1 DDX18 ALDH18A1 HDLBP

3.25e-0413671081332687490
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RANBP2 RGPD1

3.39e-049108218394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RANBP2 RGPD1

3.39e-049108228100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RANBP2 RGPD1

3.39e-049108217887960
Pubmed

Different splice variants of filamin-B affect myogenesis, subcellular distribution, and determine binding to integrin [beta] subunits.

FLNB ITGB6

3.39e-049108211807098
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RANBP2 RGPD1

3.39e-049108211553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RANBP2 RGPD1

3.39e-049108210601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RANBP2 RGPD1

3.39e-04910829733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RANBP2 RGPD1

3.39e-049108228877029
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

FLNB RANBP2 GARS1 ARCN1 TMEM177 QSOX1 G3BP1 DDX18 HDLBP

3.84e-04711108933022573
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

FLNB ARHGEF12 SYT7 KIAA1671 PHACTR4 AGFG1 IL6ST HDLBP

3.92e-04565108825468996
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

DRC7 FLNB RANBP2 ITGB6 ARCN1 VPS13D PHACTR4 HDLBP

4.06e-04568108837774976
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

FLNB ACADM STK26 NCBP1 ARCN1 G3BP1 DDX18 AGFG1 ALDH18A1 PGM2

4.17e-048781081037223481
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RANBP2 RGPD1

4.23e-0410108227160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RANBP2 RGPD1

4.23e-0410108216332688
Pubmed

Modeling progressive non-alcoholic fatty liver disease in the laboratory mouse.

LGALS3 IL6ST

4.23e-0410108224802098
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RANBP2 RGPD1

4.23e-041010828857542
Pubmed

Cbx4 Sumoylates Prdm16 to Regulate Adipose Tissue Thermogenesis.

CBX4 UCP1

4.23e-0410108229539416
InteractionLDHB interactions

ACADM CFTR MCF2L2 ARHGEF12 VIRMA PSIP1 G3BP1 PAXIP1 KCNMA1 SLFN11

8.14e-0632710510int:LDHB
InteractionHSPD1 interactions

RANBP2 ACADM GLB1L3 CFTR VARS2 BCS1L VIRMA ITGB6 DNAH1 IFNAR1 TMEM177 G3BP1 KCNMA1 ALDH18A1 SLFN11 GFM1 MGAT4C

2.05e-05102210517int:HSPD1
InteractionGFPT1 interactions

ACADM CFTR GARS1 NCBP1 VIRMA G3BP1 HDLBP

2.07e-051601057int:GFPT1
GeneFamilyNon-clustered protocadherins

PCDH12 PCDH20

9.78e-041271221
GeneFamilyDyneins, axonemal

DNAH1 DNAH17

1.99e-0317712536
GeneFamilySynaptotagmins

SYT7 SYT14

1.99e-0317712765
CoexpressionGSE17721_12H_VS_24H_POLYIC_BMDC_DN

BRIX1 ACADM NCBP1 DDX18 NUP210 PAFAH2 IL6ST HDLBP

1.83e-062001088M4102
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM ZAN HECW1 CFTR DCC DNAH1 ARFGEF3 PTPRQ

1.79e-0818410982cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM ZAN HECW1 CFTR DCC DNAH1 ARFGEF3 PTPRQ

1.79e-081841098ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAM ZAN HECW1 CFTR DCC DNAH1 ARFGEF3 PTPRQ

1.79e-0818410982b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG10 SYT7 ARFGEF3 QSOX1 HENMT1 KCNMA1 ALDH18A1

3.45e-0718310975a936fb07074cec753bf19e3e3e52499605ea22c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG10 SYT7 ARFGEF3 QSOX1 HENMT1 KCNMA1 ALDH18A1

3.45e-07183109707c18ccc45ddc9c22e482bd9ffb87f46ebcfe473
ToppCelldroplet-Fat-Mat-18m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 TRIM15 ITGB6 MGAT4C INPP5J CDH17

2.38e-061561096cfd7f56f3155db677684827607e9008e975dbe70
ToppCelldroplet-Fat-Mat-18m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 TRIM15 ITGB6 MGAT4C INPP5J CDH17

2.38e-0615610960d79b4172896574b00faf00e87254f68d76f5512
ToppCelldroplet-Fat-Mat-18m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 TRIM15 ITGB6 MGAT4C INPP5J CDH17

2.38e-061561096f09150aacb6121f913648ed3918f9cd4f22c61f2
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 CFTR LAMA2 DCC PTPRQ KCNMA1

2.76e-061601096c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 CFTR LAMA2 DCC PTPRQ KCNMA1

2.76e-06160109625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

SEMA4B ARHGEF12 VMO1 ITGB6 DNAH1 ZFP41

3.78e-061691096dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 PEG10 CFTR ARFGEF3 SHCBP1 BUB1B

4.62e-061751096fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 PEG10 CFTR ARFGEF3 SHCBP1 BUB1B

4.62e-06175109636c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLB1L3 ICAM2 PCDH12 PCDH20 NRP1 CD36

4.77e-061761096eb63eb2c301e785196ccadac74a2940b2c524c62
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ICAM2 PCDH12 NRP1 IFNAR1 KIAA1671 PHACTR4

5.97e-061831096e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4B TRIM15 LGALS3 QSOX1 SLC2A6 CDH17

6.55e-0618610964046b701aa29712d9f7c774f8955215122c3c003
ToppCell5'-Adult-Distal_Rectal-Epithelial-Tuft-related-BEST4+_epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SEMA4B TRIM15 LGALS3 QSOX1 SLC2A6 CDH17

6.55e-061861096bd5837033c1ffcbe5dd30195cc4846a2ba351bcd
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2|Children_(3_yrs) / Lineage, Cell type, age group and donor

NPC1 CFTR ITGB6 ARFGEF3 CD36 SORCS2

7.62e-061911096a0332a4ef629510fb313ec119195c44a3f704a80
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

NPC1 RANBP2 LGALS3 CD36 BUB1B SENP2

7.62e-0619110967bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

7.62e-061911096718330bb97fe8a1ffd0c82e9af23311a32eacfe1
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

7.62e-061911096454034ad940377ee079afa8ce33f8e0bdeaf44f8
ToppCellEndothelial-B|World / shred on cell class and cell subclass (v4)

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

7.62e-0619110968b7857dee69d0ba3e59e230c9fd372e14695299e
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

7.85e-0619210962360824910cd471c8286ca369ba144d90d984602
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

8.09e-061931096ac1073bf4d3868841226b850b058f1e27326a14e
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

8.33e-061941096fc40ab57be3a15c043e3414c2c678c1dc52207c8
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BRIX1 COL11A2 PEG10 PRDX2 TMTC3 DDX18

8.33e-06194109640c6e17e9e48d4fa6da3a0a1066c4c6565a1e096
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

8.33e-06194109650fa7c7940b113427c87fbdb9057fef8e1ce52c5
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

8.33e-0619410968deeb3e00237e3d9ad5a1457cd0061576421b9e9
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36 AGFG1

8.33e-061941096b81801fb16e8bd0d6083fe32866051d3c60f3dc7
ToppCelldistal-2-Epithelial-Club|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SEMA4B PEG10 CFTR ITGB6 PCDH20 ARFGEF3

9.36e-0619810963055c03896fbfac82a3072e51c0c54d68131cf1a
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FLNB VMO1 PCDH20 CAPN13 CD36 IL6ST

9.63e-06199109632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPC1 PEG10 CFTR ITGB6 ARFGEF3 CNR1

9.63e-0619910962dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNB ARHGEF12 PCDH12 SYT7 NRP1 CD36

9.91e-062001096a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TRIM15 CFTR TSPEAR UCP1

3.29e-057410940d705c42e7741b861ba5a9f1af83b2c5c6f23fb6
ToppCellPosterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

TRIM15 CFTR TSPEAR UCP1

3.29e-05741094c49bda52aa4ead9483c2f27d63458034e75699bd
ToppCellfacs-Skin-nan-24m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZYG11A FLNB LGALS3 SYT14 KCNMA1

3.98e-051551095fa2776d258e0420b2895de1008e292ad7725dac0
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFTR CFAP43 VMO1 CAPN13 ARFGEF3

5.52e-0516610951df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFTR CFAP43 VMO1 CAPN13 ARFGEF3

5.52e-0516610959628522e7af8f8edca733588a364ab2454ac5ca5
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5|TCGA-Bladder / Sample_Type by Project: Shred V9

COL11A2 PEG10 CFAP43 MGAT4C CNR1

6.01e-0516910959c4e83fe8225d16173a103bf5a57b17d623be923
ToppCell-Hematopoietic_Mast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LGALS3 PAOX PGM2

6.52e-05321093ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell-Hematopoietic_Mast-Mast_cells-Mast-cells| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LGALS3 PAOX PGM2

6.52e-05321093c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell-Hematopoietic_Mast-Mast_cells| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LGALS3 PAOX PGM2

6.52e-05321093de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma-4|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

ICAM2 PCDH12 CD36 CARD6 AGFG1

7.08e-05175109516849ea8f0985108baa2085f34c3de14a4f9f28b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

COL11A2 ICAM2 PCDH12 CD36 CARD6

7.68e-05178109560263c0bb9de3a57ba2ba543262a2ace0066fd85
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DRC7 DYNC2I1 CFAP43 SYT14 CFAP74

7.88e-0517910955e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PEG10 OVOS2 CD36 MGAT4C CNR1

8.09e-051801095b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCellMS-Treg-naive_CD4|MS / Condition, Cell_class and T cell subcluster

FLNB MTMR12 PAFAH2 CARD6 CFAP74

8.09e-0518010957ca083616926d98420fa11a6e5ebc981623f79ac
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SEMA4B VMO1 PCDH20 CAPN13 WDR87

8.09e-051801095535a890bde0d978b461c2d4c571529b585c76b21
ToppCellLPS_only-Epithelial_alveolar-AT_2-AT2_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CFTR TSPEAR VARS2 ITGB6 ARFGEF3

8.30e-0518110950513b9e6673ff7bf8e72ba123ca3794b65d10170
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MCF2L2 SYT7 SYT14 MGAT4C CNR1

8.52e-051821095be32b5b8153c1053cbb55f1fccfa27c3ee97c1e1
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLB1L3 ICAM2 PCDH20 NRP1 CD36

8.52e-0518210953b4dbf61ca0fe50efe05449815630e301cb76630
ToppCelldroplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLB1L3 ICAM2 PCDH20 NRP1 CD36

8.52e-051821095ab5761bf9af439231cd0f487b6467e372672a517
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|lung / Disease (COVID-19 only), tissue and cell type

ZYG11A DCC SHCBP1 NUP210 BUB1B

8.97e-051841095480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYNC2I1 CFAP43 DNAH1 TRIM56 CFAP74

8.97e-051841095264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 PEG10 ARHGEF12 CAPN13 SORCS2

8.97e-051841095102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYNC2I1 CFAP43 DNAH1 TRIM56 CFAP74

8.97e-051841095d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYNC2I1 CFAP43 DNAH1 TRIM56 CFAP74

8.97e-05184109522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellControl-Epithelial_alveolar-AT_2-AT2_Progenitor|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TSPEAR VARS2 ITGB6 LGALS3 CD36

9.20e-0518510958ca1374501eca01d8468130b74d50abfd4329fbe
ToppCellfacs-Heart-RV|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ICAM2 PCDH12 NRP1 CD36

9.20e-0518510957cf2b0db059605032bfae60cf1b93c4c62608f0c
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SALL3 PCDH12 SYT7 TRIM56 IL6ST

9.20e-051851095bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTN4 CFTR ITGB6 ARFGEF3 SORCS2

9.44e-0518610952ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellfacs-Heart-LA-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ICAM2 NRP1 KIAA1671 CD36

9.44e-051861095f8ed078684ce6d914fd9cb1f0ef4aba36db39b3f
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

ZYG11A DCC SHCBP1 NUP210 BUB1B

9.44e-05186109566676d9395172de5707e204826a1c9f73b448cca
ToppCellfacs-Heart-LA-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ICAM2 NRP1 KIAA1671 CD36

9.44e-0518610951d08e60d239153c9e5ea42135d702d494d8b42b1
ToppCellP28-Endothelial-unknown_endothelial_cell-endothelial_unknown_1|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ICAM2 ARHGEF12 NRP1 CD36 AGFG1

9.44e-051861095a38f84f478798951c8798c8e90e4897c729cf630
ToppCell(4)_Lymph_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

ICAM2 OVOS2 PCDH12 CD36 MGAT4C

9.44e-0518610956b3afc2ae870ff73e30a60ce84fcee0eb365d809
ToppCellP28-Endothelial-unknown_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ICAM2 ARHGEF12 NRP1 CD36 AGFG1

9.44e-051861095dde38decf368775694bbeae38a3ff084017c34ab
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

ZGRF1 SHCBP1 BUB1B KCNMA1 ALDH18A1

9.44e-0518610955cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ICAM2 PCDH12 NRP1 KIAA1671 PHACTR4

9.68e-051871095ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

CNTN4 CFTR ITGB6 ARFGEF3 SORCS2

9.68e-05187109581cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ZYG11A MGAM HECW1 LIN52

9.68e-051871095dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ZYG11A MGAM HECW1 LIN52

9.68e-051871095f1356273bd3587b6883295edf15cb9cdb706c057
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB ICAM2 PCDH12 KIAA1671 CD36

9.68e-051871095dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ICAM2 PCDH12 KIAA1671 ARFGEF3 CARD6

9.68e-05187109503de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL4 PHACTR4 PAXIP1 KCNMA1 SENP2

9.93e-0518810956468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL4 PHACTR4 PAXIP1 KCNMA1 SENP2

9.93e-0518810957a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TTLL4 PHACTR4 PAXIP1 KCNMA1 SENP2

9.93e-0518810959cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

CFTR ITGB6 ARFGEF3 CD36 SORCS2

1.02e-041891095dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellCOVID-19-lung-Secretory|lung / Disease (COVID-19 only), tissue and cell type

CNTN4 FLNB CFTR CAPN13 ARFGEF3

1.02e-04189109584d48e3ed25bebb8bb8074b3a2c5e2e88cff7f25
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 HECW1 DCC NRP1 SYT14

1.02e-04189109528b502611829e4a24caff2562545c7db97686099
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFTR ITGB6 CD36 PTPRQ SORCS2

1.04e-0419010958aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellfacs-Heart-LA-24m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNB ICAM2 NRP1 KIAA1671 CD36

1.04e-041901095911b93c4c828ef2d867b91a5eced2dc12a1baf27
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ICAM2 PCDH12 KIAA1671 UCP1 CARD6

1.07e-041911095edfd5eeff69b5de19c5df3d899e42acd7e015913
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 HECW1 DCC NRP1 KIAA1671

1.07e-0419110953c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 HECW1 DCC NRP1 KIAA1671

1.07e-0419110951c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

ICAM2 PCDH12 KIAA1671 CD36 NUP210

1.07e-04191109544c596984c6196f6014e0e405dbe5560841e54ff
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

ICAM2 PCDH12 KIAA1671 CD36 NUP210

1.07e-041911095e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 CFTR ITGB6 ARFGEF3 SORCS2

1.07e-041911095e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ICAM2 PCDH12 KIAA1671 UCP1 CARD6

1.10e-041921095ac3d87aa301d30515c369bd7fc16f33b82173a85
ToppCellEC|World / Lineage and Cell class

ICAM2 PCDH12 SYT7 NRP1 CD36

1.10e-041921095478866dd5b0d6ff3a76d07a17c4b5989dd7a27bb
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FLNB ICAM2 PCDH12 KIAA1671 CD36

1.10e-0419210950aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

CFTR ITGB6 ARFGEF3 CD36 SORCS2

1.10e-04192109558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellCiliated-cil-3|World / Class top

DRC7 DYNC2I1 CFAP43 DNAH1 CFAP74

1.10e-0419210954989ebb8812b8af1870599acd932849122c05a29
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MXRA5 COL11A2 STK26 LGALS3 KCNMA1

1.10e-0419210953a6f2c255da46a0b0f5b657b0f56f3d7798ae85a
ToppCellEndothelial-Endothelial-B|Endothelial / shred on cell class and cell subclass (v4)

ICAM2 ARHGEF12 NRP1 CD36 AGFG1

1.10e-041921095f8d7bd81e031d09a557722627c2f6180811cc6ab
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-large_intestine_goblet_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYT7 ARFGEF3 QSOX1 KCNMA1 HDLBP

1.12e-0419310956a9bce5064938b5b84ad57b4fd4a7841afe100c8
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM15 BMP2K HECTD4 ARHGEF12 PRDX2

1.12e-041931095305e15ee467826ee08b2617c69f250ad39c11b19
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ICAM2 ARHGEF12 PCDH12 NRP1 CD36

1.12e-041931095097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM15 BMP2K HECTD4 ARHGEF12 PRDX2

1.12e-041931095dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCell3'-Child04-06-SmallIntestine-Epithelial-goblet-Goblet_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYT7 LGALS3 ARFGEF3 QSOX1 CDH17

1.15e-04194109549cc5f5de4380302100e8cd937f08abe317ac75e
DiseaseWeight Gain

ACADM ARHGEF12 VPS13D CD36 KCNMA1 CNR1

1.60e-061021036C0043094
DiseaseColorectal Carcinoma

DPAGT1 CNTN4 SALL3 CFTR MCF2L2 TSPEAR DCC SACS BUB1B IL6ST

1.76e-0470210310C0009402
Diseasesevere acute respiratory syndrome, COVID-19

CNTN4 SEMA4B MXRA5 NUP210 SYT14 SORCS2 KCNMA1 PGM2

1.76e-044471038EFO_0000694, MONDO_0100096
Diseasepsoriatic arthritis, psoriasis

CNTN4 PAXIP1

1.79e-0461032EFO_0000676, EFO_0003778
DiseaseGrowth Disorders

CNTN4 BUB1B KCNMA1

2.71e-04361033C0018273
Diseasegallbladder neoplasm

CNTN4 DCC

4.28e-0491032EFO_0004606
DiseaseHypermetropia, Myopia

MCF2L2 LAMA2 DYNC2I1 SYT14 KCNMA1

5.39e-041891035HP_0000540, HP_0000545
Diseasepain

LAMA2 POM121L2 DCC CAPN13 RPRD2

6.35e-041961035EFO_0003843
DiseaseObesity

NPC1 ACADM UCP1 KCNMA1 CNR1

7.77e-042051035C0028754
Diseasecleft palate (is_implicated_in)

FLNB COL11A2

7.78e-04121032DOID:674 (is_implicated_in)
Diseasehuman papilloma virus infection, oropharynx cancer

CNTN4 TRIM15 PAOX

8.52e-04531033EFO_0001668, EFO_1001931
DiseaseRhabdomyosarcoma

BUB1B CNR1

1.23e-03151032C0035412
DiseaseTremor, Rubral

NPC1 ARCN1

1.40e-03161032C0750940
DiseaseAtaxia, Appendicular

NPC1 ARCN1

1.40e-03161032C0750937
DiseaseAtaxia, Motor

NPC1 ARCN1

1.40e-03161032C0278161
DiseaseIschemic stroke, plasminogen activator inhibitor 1 measurement

HECTD4 TRIM56

1.40e-03161032EFO_0004792, HP_0002140
DiseaseAtaxia, Sensory

NPC1 ARCN1

1.40e-03161032C0240991
DiseaseAbnormal coordination

NPC1 ARCN1

1.40e-03161032C0520966
DiseaseAtaxia, Truncal

NPC1 ARCN1

1.40e-03161032C0427190
Diseaseesophageal adenocarcinoma

HECW1 CFTR

1.78e-03181032EFO_0000478
Diseaseosteochondrodysplasia (is_implicated_in)

FLNB COL11A2

1.99e-03191032DOID:2256 (is_implicated_in)
DiseaseLiver diseases

NPC1 ITGB6 NRP1

2.07e-03721033C0023895
DiseaseLiver Dysfunction

NPC1 ITGB6 NRP1

2.07e-03721033C0086565
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

DCC SYT7

2.43e-03211032OBA_2045104
DiseaseEsophageal Neoplasms

PRDX2 DCC LGALS3

2.60e-03781033C0014859
DiseaseMalignant neoplasm of esophagus

PRDX2 DCC LGALS3

2.60e-03781033C0546837
DiseaseColorectal Neoplasms

DPAGT1 CFTR DCC BUB1B IL6ST

2.91e-032771035C0009404
Diseaseliver cirrhosis (is_marker_for)

ITGB6 LGALS3 CD36

3.00e-03821033DOID:5082 (is_marker_for)
Diseasesuicidal ideation, suicide behaviour

POM121L2 DCC

3.17e-03241032EFO_0004320, EFO_0007623
DiseaseAtaxia

NPC1 ARCN1

3.44e-03251032C0004134

Protein segments in the cluster

PeptideGeneStartEntry
SKGPSVPFSIFDEFL

BUB1B

521

O60566
FFNETDVVFPQSLPK

CFAP43

206

Q8NDM7
FGVIPQKVFIFSGTF

CFTR

1286

P13569
ISTKFEFVPSPGNHF

BCS1L

91

Q9Y276
SVHPFSPFEVKVGVF

CNTN4

766

Q8IWV2
PKSQPFVDHVFTFTI

BRIX1

196

Q8TDN6
KFPPVFFSSFRNTVQ

CAPN13

421

Q6MZZ7
PKAPANKAFTGFIVE

ACADM

211

P11310
TFSEEVFLAQKPGAP

DENND1C

356

Q8IV53
PKQEFDVFGAVPFFA

BMP2K

851

Q9NSY1
PKSVDVFGSTPFQPF

BMP2K

926

Q9NSY1
TPKPFRKFDSVAFGE

ARHGEF12

736

Q9NZN5
PPKFVFGSESVKSIF

RANBP2

2511

P49792
PGFPTVRFFKAFTKN

QSOX1

116

O00391
TFQTFGKAEAPELSP

PCDH12

1086

Q9NPG4
TPFVLFTGFEPVQVQ

PAXIP1

866

Q6ZW49
KPAVFDFPSQDVFTV

NUP210

1616

Q8TEM1
KPPSTGDVFVIVFEN

MGAT4C

371

Q9UBM8
SPRFINKDFSFFVPE

PCDH20

636

Q8N6Y1
ETVFKLTPEFFSPGK

C22orf46

86

C9J442
PPAEAKGNIQTFTVF

DCC

451

P43146
LPGVAEFAASFKSPI

LIN52

36

Q52LA3
VNSVVDFFTVPPVFV

KCNMA1

246

Q12791
KQGSPVEPKATFFAV

KIAA1671

1016

Q9BY89
GFSFNPLKIEVFVQT

NCBP1

536

Q09161
IPIFSTFFFNSPHQK

MTMR12

486

Q9C0I1
FLPFISSGFAPRFKQ

GLB1L3

21

Q8NCI6
QSPAVKFITNPEFFT

HECW1

951

Q76N89
QLDFTLSPKFAGFPA

MGAM

1286

O43451
RQSVFPFESGKPFKI

LGALS3

186

P17931
KVNVIDFSPFGEPIF

DYNC2I1

911

Q8WVS4
PITKFDASVIAPFFP

HMGXB3

946

Q12766
APIITFPEFSGFKHI

MCF2L2

61

Q86YR7
FTNFGNTTIVVPKPF

DPAGT1

141

Q9H3H5
FFAGDTIPKSPFVVQ

FLNB

431

O75369
EVDSFTPFRKAQIGP

IFNAR1

116

P17181
RLGFGSFVEKPVSPF

ITGB6

171

P18564
FRFFQELPGSDPVFK

PDXDC2P

391

Q6P474
FPGGFPKDFSLLTVV

COL11A2

76

P13942
SFVQSAFKAFDLVPP

PGM2

261

Q96G03
SFDVTQSPFFPVVLG

PEG10

431

Q86TG7
VYTVSFPKPGFVELS

LAMA2

2526

P24043
VSQPFFIEIASPFSV

OVOS2

776

Q6IE36
LSFGFKVPPFVDLNV

DDX18

611

Q9NVP1
PPSLNFKVEGDTVTF

HECTD4

721

Q9Y4D8
SFLPVVSTFGLQVPF

SLC2A6

451

Q9UGQ3
PAPDFKATAVVDGAF

PRDX2

11

P32119
FPAKTFQVVPEIEFP

PHACTR4

361

Q8IZ21
TFFSEVKPAGPTVEQ

ALDH18A1

351

P54886
DPFLFQTAESAPGKV

PTPRQ

186

Q9UMZ3
KDNGQAPFTITPVFS

NPC1

196

O15118
PVVSSGPFLFIKFVS

NRP1

111

O14786
KFTPRVGSFEVPEDF

DNAH1

131

Q9P2D7
TPFCVGDKFFVPLQR

HENMT1

331

Q5T8I9
KDGPEFTFTTPKFAQ

IL6ST

601

P40189
GIKQPEAPEITVFFS

CARD6

121

Q9BX69
FPFKAGVVSPVDFLQ

DNAH17

3756

Q9UFH2
INGTDAASFPPFVEK

CD36

246

P16671
KLPNFGFVVFDDSEP

G3BP1

376

Q13283
IFKGDPFFILPSFQS

ARFGEF3

1931

Q5TH69
PAESLSEFKPFFGNI

CBX4

526

O00257
QKFPLTSFRGSPFQE

CNR1

46

P21554
KREVPENFFIDPFTG

DRC7

311

Q8IY82
PKQEFDIFGAVPFFA

BMP2KL

106

Q5H9B9
PKSIDIFDFTPFQPF

BMP2KL

176

Q5H9B9
FKANPPAVTFELTGE

CDH17

51

Q12864
DETFGSNIPKQFVPA

GFM1

571

Q96RP9
QEFGVKSAFPPSVRA

RPRD2

881

Q5VT52
LPAVSEQFKAQFPFG

SALL3

636

Q9BXA9
RFFVPPTFKSVGNPV

SACS

4431

Q9NZJ4
EFGFVRLPKFVDVQP

CFAP74

951

Q9C0B2
QPNDFFPVQVSFVSK

ARCN1

461

P48444
PKARGPVFFINTEKF

PAFAH2

271

Q99487
AVVSPPKFVFGSESV

RGPD1

1516

P0DJD0
FQEAAFPGETFPVSV

PAOX

256

Q6QHF9
PIFNESFAFDIPTEK

SYT7

331

O43581
PVSFGLLFSVAFPVD

VARS2

311

Q5ST30
AASLFGFPFQLTTKP

SENP2

66

Q9HC62
IQRGPCPVFTETFKF

SYT14

316

Q8NB59
PPTLVGDFTKSFKEF

STK26

236

Q9P289
QRTFFSFPAVVAPFK

GARS1

601

P41250
PFDPNFKSTALVVDG

SEMA4B

186

Q9NPR2
DEGATFQKQPIPFFV

SORCS2

236

Q96PQ0
PFPESQLVEFKQFST

SLFN11

206

Q7Z7L1
GFFASGFSLKVEPPQ

VMO1

56

Q7Z5L0
PEGKTFFPEIFQTNQ

SHCBP1

61

Q8NEM2
FGKAAPAPQEATATF

ICAM2

161

P13598
VFKPPLDFGVVNVTS

POM121L2

636

Q96KW2
FAAFGQTKPVVTPFG

AGFG1

516

P52594
FLTTVFKAGSQSFPP

NLRP9

371

Q7RTR0
PTNKLPIFFFGTHET

PSIP1

36

O75475
PLNFAPTFKFDVGTN

INPP5J

651

Q15735
NEGPTAFFKGLVPSF

UCP1

261

P25874
ASFKDDFEGVPVFIP

ZFP41

66

Q8N8Y5
NPSPETVLFFSGKVE

TMEM94

426

Q12767
AKSPVFSDVPFLTGQ

SPATA31D1

1546

Q6ZQQ2
PIFTFTASFSGKVFP

TRIM15

436

Q9C019
FFNSPPRKTVQFGGT

RRN3P2

41

A6NIE6
KFIPPAFTNVSTKFE

ZGRF1

1581

Q86YA3
PFPATLSVKGARFFV

TSPEAR

186

Q8WU66
SSEEFPSFGAQVAPK

HDLBP

1246

Q00341
PASNLFFPVGFVVAE

TMTC3

361

Q6ZXV5
KPFTTFTFQPVSAGF

TMEM177

81

Q53S58
GKKEFSFFPQSFILP

TTLL4

686

Q14679
LFFNNVSKPSAPVFD

VIRMA

71

Q69YN4
FKTFFPLLGNFSQPE

ZYG11A

671

Q6WRX3
VLEVPKPFIPSFFFS

WDR87

656

Q6ZQQ6
PPEGVASFKTNFFVN

TRIM56

66

Q9BRZ2
QFAVVGVFGKTPEPA

ZAN

341

Q9Y493
PFRIDNFSKVPVVFT

VPS13D

3516

Q5THJ4
FGAPIQAFSVFPKER

ART5

206

Q96L15
PFFTNKTLSFPQLGV

MXRA5

1731

Q9NR99