Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

CAPN9 EYS PCDH19 PCDHB5 TTYH2 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 ITLN2 CAPS2 CDH3

4.80e-057499413GO:0005509
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 CDH3

1.38e-0753936GO:0016339
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

2.07e-06187938GO:0007156
GeneOntologyBiologicalProcesspositive regulation of collagen catabolic process

IDUA VSIR

2.01e-052932GO:0120158
GeneOntologyBiologicalProcesspositive regulation of double-strand break repair via nonhomologous end joining

RIF1 SHLD1 TOP2B

5.76e-0517933GO:2001034
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

8.56e-05313938GO:0098742
GeneOntologyBiologicalProcesspositive regulation of basement membrane assembly involved in embryonic body morphogenesis

CLASP2 PHLDB2

1.99e-045932GO:1904261
GeneOntologyBiologicalProcessregulation of basement membrane assembly involved in embryonic body morphogenesis

CLASP2 PHLDB2

1.99e-045932GO:1904259
GeneOntologyBiologicalProcessnegative regulation of wound healing, spreading of epidermal cells

CLASP2 PHLDB2

1.99e-045932GO:1903690
GeneOntologyBiologicalProcessbasement membrane assembly involved in embryonic body morphogenesis

CLASP2 PHLDB2

1.99e-045932GO:2001197
GeneOntologyCellularComponentmultivesicular body lumen

PGA4 PGA5 PGA3

3.04e-067943GO:0097486
GeneOntologyCellularComponentlate endosome lumen

PGA4 PGA5 PGA3

1.42e-0511943GO:0031906
GeneOntologyCellularComponentbasal cortex

CLASP2 PHLDB2

4.14e-047942GO:0045180
DomainCadherin_CS

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

7.62e-08109948IPR020894
DomainCADHERIN_1

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.01e-07113948PS00232
DomainCadherin

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.01e-07113948PF00028
DomainCADHERIN_2

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.08e-07114948PS50268
Domain-

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.08e-071149482.60.40.60
DomainCA

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.16e-07115948SM00112
DomainCadherin-like

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.24e-07116948IPR015919
DomainCadherin

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 CDH23 PCDHA3 CDH3

1.41e-07118948IPR002126
DomainCadherin_2

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

8.99e-0765946PF08266
DomainCadherin_N

PCDH19 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

8.99e-0765946IPR013164
DomainAspartic_peptidase_N

PGA4 PGA5 PGA3

4.26e-067943IPR012848
DomainA1_Propeptide

PGA4 PGA5 PGA3

4.26e-067943PF07966
DomainAspartic_peptidase_A1

PGA4 PGA5 PGA3

1.44e-0510943IPR001461
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

1.44e-0510943IPR033121
DomainAsp

PGA4 PGA5 PGA3

1.44e-0510943PF00026
DomainPEPTIDASE_A1

PGA4 PGA5 PGA3

1.44e-0510943PS51767
Domain-

PGA4 PGA5 PGA3

2.63e-05129432.40.70.10
DomainASP_PROTEASE

PGA4 PGA5 PGA3

2.63e-0512943PS00141
DomainAspartic_peptidase_AS

PGA4 PGA5 PGA3

3.40e-0513943IPR001969
DomainCadherin_C

PCDHB5 PCDHB8 PCDHGB4 PCDHB4

5.82e-0542944IPR032455
DomainCadherin_C_2

PCDHB5 PCDHB8 PCDHGB4 PCDHB4

5.82e-0542944PF16492
DomainPeptidase_aspartic_dom

PGA4 PGA5 PGA3

7.98e-0517943IPR021109
DomainNCD3G

TAS1R1 GRM4

1.89e-0313942PF07562
DomainGPCR_3_9-Cys_dom

TAS1R1 GRM4

1.89e-0313942IPR011500
Domain-

ACBD5 PLEKHH2 EPB41L3

1.92e-03499431.20.80.10
DomainFERM/acyl-CoA-bd_prot_3-hlx

ACBD5 PLEKHH2 EPB41L3

2.04e-0350943IPR014352
DomainGPCR_3_CS

TAS1R1 GRM4

2.19e-0314942IPR017979
DomainTF_T-box

TBX22 TBR1

3.24e-0317942IPR001699
DomainTBOX

TBX22 TBR1

3.24e-0317942SM00425
DomainTF_T-box_CS

TBX22 TBR1

3.24e-0317942IPR018186
Domain-

TBX22 TBR1

3.24e-03179422.60.40.820
DomainTBOX_3

TBX22 TBR1

3.24e-0317942PS50252
DomainT-box

TBX22 TBR1

3.24e-0317942PF00907
DomainTBOX_1

TBX22 TBR1

3.24e-0317942PS01283
DomainTBOX_2

TBX22 TBR1

3.24e-0317942PS01264
DomainCH

MICAL2 NAV3 NAV2

4.30e-0365943SM00033
DomainGPCR_3

TAS1R1 GRM4

4.95e-0321942IPR000337
DomainCH

MICAL2 NAV3 NAV2

5.30e-0370943PF00307
Domain7tm_3

TAS1R1 GRM4

5.42e-0322942PF00003
DomainG_PROTEIN_RECEP_F3_2

TAS1R1 GRM4

5.42e-0322942PS00980
DomainG_PROTEIN_RECEP_F3_3

TAS1R1 GRM4

5.42e-0322942PS00981
DomainG_PROTEIN_RECEP_F3_1

TAS1R1 GRM4

5.42e-0322942PS00979
DomainG_PROTEIN_RECEP_F3_4

TAS1R1 GRM4

5.42e-0322942PS50259
DomainGPCR_3_C

TAS1R1 GRM4

5.42e-0322942IPR017978
Domain-

MICAL2 NAV3 NAV2

5.51e-03719431.10.418.10
DomainCH

MICAL2 NAV3 NAV2

5.95e-0373943PS50021
PathwayWP_GASTRIC_ACID_PRODUCTION

PGA4 PGA5 PGA3

1.57e-0511663M39726
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

SP8 PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

1.28e-085895630377227
Pubmed

The epidemiology of low serum pepsinogen A levels and an international association with gastric cancer rates. EUROGAST Study Group.

PGA4 PGA5 PGA3

1.97e-0839537926498
Pubmed

Crystal structure of human pepsinogen A.

PGA4 PGA5 PGA3

1.97e-0839539561228
Pubmed

The combination of serum trefoil factor 3 and pepsinogen testing is a valid non-endoscopic biomarker for predicting the presence of gastric cancer: a new marker for gastric cancer risk.

PGA4 PGA5 PGA3

1.97e-08395321455714
Pubmed

Serum pepsinogen level, atrophic gastritis and the risk of incident pancreatic cancer--a prospective cohort study.

PGA4 PGA5 PGA3

1.97e-08395319800305
Pubmed

Serum pepsinogen reference intervals in apparently healthy Chinese population with latex enhanced turbidimetric immunoassay.

PGA4 PGA5 PGA3

1.97e-08395324170207
Pubmed

Relationships between the human pepsinogen DNA and protein polymorphisms.

PGA4 PGA5 PGA3

1.97e-0839533014868
Pubmed

The ratio of pepsinogen A to pepsinogen C: a sensitive test for atrophic gastritis.

PGA4 PGA5 PGA3

1.97e-0839532799289
Pubmed

CRYSTALLINE PEPSIN : I. ISOLATION AND TESTS OF PURITY.

PGA4 PGA5 PGA3

1.97e-08395319872561
Pubmed

Human pepsinogen A (PGA): an informative gene complex located at 11q13.

PGA4 PGA5 PGA3

1.97e-0839531968039
Pubmed

Helicobacter pylori infection and serum pepsinogen A, pepsinogen C, and gastrin in gastritis and peptic ulcer: significance of inflammation and effect of bacterial eradication.

PGA4 PGA5 PGA3

1.97e-0839538053437
Pubmed

Family and population studies on the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

1.97e-0839532566575
Pubmed

Immunoblot technique to visualise serum pepsinogen A isozymogen patterns.

PGA4 PGA5 PGA3

1.97e-0839532229438
Pubmed

Prediction of gastric cancer development by serum pepsinogen test and Helicobacter pylori seropositivity in Eastern Asians: a systematic review and meta-analysis.

PGA4 PGA5 PGA3

1.97e-08395325314140
Pubmed

Validation of the pepsinogen test method for gastric cancer screening using a follow-up study.

PGA4 PGA5 PGA3

1.97e-08395319890696
Pubmed

Diagnostic value of serum pepsinogen C in patients with raised serum concentrations of pepsinogen A.

PGA4 PGA5 PGA3

1.97e-0839538244094
Pubmed

Plasma pepsinogens, antibodies against Helicobacter pylori, and risk of gastric cancer in the Shanghai Women's Health Study Cohort.

PGA4 PGA5 PGA3

1.97e-08395321407214
Pubmed

Isolation of an activation intermediate and determination of the amino acid sequence of the activation segment of human pepsinogen A.

PGA4 PGA5 PGA3

1.97e-0839536774973
Pubmed

Primary structure of human pepsinogen gene.

PGA4 PGA5 PGA3

1.97e-0839536300126
Pubmed

Pepsinogen I/II ratio is related to glucose, triacylglycerol, and uric acid levels.

PGA4 PGA5 PGA3

1.97e-08395322304859
Pubmed

Pepsinogen I and II expressions in situ and their correlations with serum pesignogen levels in gastric cancer and its precancerous disease.

PGA4 PGA5 PGA3

1.97e-08395324004680
Pubmed

Effect of enprostil on serum gastrin and pepsinogen A and C levels in patients on long-term treatment with omeprazole.

PGA4 PGA5 PGA3

1.97e-0839538038355
Pubmed

Human pepsinogen A isozymogen patterns in serum and gastric mucosa.

PGA4 PGA5 PGA3

1.97e-0839532227273
Pubmed

Identification of a high risk gastric cancer group using serum pepsinogen after successful eradication of Helicobacter pylori.

PGA4 PGA5 PGA3

1.97e-08395323034090
Pubmed

A possible association of low pepsinogen I and pepsinogen I/II with low and high body weight in Japanese men.

PGA4 PGA5 PGA3

1.97e-08395324125879
Pubmed

Effects of omeprazole and lansoprazole on fasting and postprandial serum gastrin and serum pepsinogen A and C.

PGA4 PGA5 PGA3

1.97e-0839538751234
Pubmed

Enzyme-linked immunosorbent assay and radioimmunoassay of serum pepsinogen A.

PGA4 PGA5 PGA3

1.97e-0839533554488
Pubmed

Expression of serum miR-20a-5p, let-7a, and miR-320a and their correlations with pepsinogen in atrophic gastritis and gastric cancer: a case-control study.

PGA4 PGA5 PGA3

1.97e-08395323521833
Pubmed

Close linkage of human chromosomal pepsinogen A genes.

PGA4 PGA5 PGA3

1.97e-0839533017318
Pubmed

Serum pepsinogen test for early detection of gastric cancer in a European country.

PGA4 PGA5 PGA3

1.97e-08395321989121
Pubmed

Serum antibodies to H+,K+-ATPase, serum pepsinogen A and Helicobacter pylori in relation to gastric mucosa morphology in patients with low or low-normal concentrations of serum cobalamins.

PGA4 PGA5 PGA3

1.97e-0839539855083
Pubmed

Advantages of serum pepsinogen A combined with gastrin or pepsinogen C as first-line analytes in the evaluation of suspected cobalamin deficiency: a study in patients previously not subjected to gastrointestinal surgery.

PGA4 PGA5 PGA3

1.97e-0839539797498
Pubmed

The glomerular sieving of pepsinogen A and C in man.

PGA4 PGA5 PGA3

1.97e-0839532478370
Pubmed

Clinical significance of pepsinogen A isozymogens, serum pepsinogen A and C levels, and serum gastrin levels.

PGA4 PGA5 PGA3

1.97e-0839533815274
Pubmed

Pepsinogens: physiology, pharmacology pathophysiology and exercise.

PGA4 PGA5 PGA3

1.97e-08395310675278
Pubmed

Pepsinogen A polymorphism in gastric mucosa and urine, with special reference to patients with gastric cancer.

PGA4 PGA5 PGA3

1.97e-0839533780036
Pubmed

Identification of a Glu greater than Lys substitution in the activation segment of human pepsinogen A-3 and -5 isozymogens by peptide mapping using endoproteinase Lys-C.

PGA4 PGA5 PGA3

1.97e-0839532901984
Pubmed

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11.

PGA4 PGA5 PGA3

1.97e-0839533839486
Pubmed

Assignment of the pepsinogen gene complex (PGA) to human chromosome region 11q13 by in situ hybridization.

PGA4 PGA5 PGA3

1.97e-0839533467902
Pubmed

The pepsinogens of human gastric mucosa.

PGA4 PGA5 PGA3

1.97e-0839534586732
Pubmed

Genomic structure and evolution of the human pepsinogen A multigene family.

PGA4 PGA5 PGA3

1.97e-0839532892778
Pubmed

The value of serum pepsinogen levels for the diagnosis of gastric diseases in Chinese Han people in midsouth China.

PGA4 PGA5 PGA3

1.97e-08395324383519
Pubmed

Gene structures of pepsinogens A and C.

PGA4 PGA5 PGA3

1.97e-0839531455184
Pubmed

Hypomethylation and expression of pepsinogen A genes in the fundic mucosa of human stomach.

PGA4 PGA5 PGA3

1.97e-0839532831884
Pubmed

Localization of pepsinogen (A and C) and cellular differentiation of pepsinogen-synthesizing cells in the human gastric mucosa.

PGA4 PGA5 PGA3

1.97e-0839532032552
Pubmed

Analysis of the promoter of a human pepsinogen A gene.

PGA4 PGA5 PGA3

1.97e-0839531812762
Pubmed

O6-methylguanine in blood leucocyte DNA: an association with the geographic prevalence of gastric cancer and with low levels of serum pepsinogen A, a marker of severe chronic atrophic gastritis. The EUROGAST Study Group.

PGA4 PGA5 PGA3

1.97e-0839537923573
Pubmed

Fast detection of phosphorylation of human pepsinogen A, human pepsinogen C and swine pepsinogen using a combination of reversed-phase high-performance liquid chromatography and capillary zone electrophoresis for peptide mapping.

PGA4 PGA5 PGA3

1.97e-0839539061458
Pubmed

Ratio between serum IL-8 and pepsinogen A/C: a marker for atrophic body gastritis.

PGA4 PGA5 PGA3

1.97e-08395312588289
Pubmed

Gastric cancer detection using gastric juice pepsinogen and melanoma-associated gene RNA.

PGA4 PGA5 PGA3

1.97e-08395323897256
Pubmed

An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse.

PGA4 PGA5 PGA3

1.97e-08395311566730
Pubmed

The effect of acute and chronic protein loading on urinary pepsinogen A excretion.

PGA4 PGA5 PGA3

1.97e-0839531956484
Pubmed

Transcription regulation of human and porcine pepsinogen A.

PGA4 PGA5 PGA3

1.97e-0839538540382
Pubmed

Exploratory findings of audiometry in adult patients with otitis media with high pepsinogen concentrations: a preliminary study.

PGA4 PGA5 PGA3

1.97e-08395322992016
Pubmed

The role of serum pepsinogen in the detection of gastric cancer.

PGA4 PGA5 PGA3

1.97e-08395320981206
Pubmed

Gastric chief cell-specific transcription of the pepsinogen A gene.

PGA4 PGA5 PGA3

1.97e-0839538504820
Pubmed

Detection of pepsinogen in the neonatal lung and stomach by immunohistochemistry.

PGA4 PGA5 PGA3

1.97e-08395321970995
Pubmed

Serum pepsinogens in gastric cancer screening.

PGA4 PGA5 PGA3

1.97e-08395320428942
Pubmed

The relationship of Helicobacter pylori colonization, the serum pepsinogen A level, and gastric resection.

PGA4 PGA5 PGA3

1.97e-0839539525001
Pubmed

Evaluation of pepsinogen A and gastrin-17 as markers of gastric cancer and high-risk pathologic conditions.

PGA4 PGA5 PGA3

1.97e-0839537886402
Pubmed

Serum pepsinogen and gastric cancer screening.

PGA4 PGA5 PGA3

1.97e-08395317379991
Pubmed

Low serum pepsinogen I and pepsinogen I/II ratio and Helicobacter pylori infection are associated with increased risk of gastric cancer: 14-year follow up result in a rural Chinese community.

PGA4 PGA5 PGA3

1.97e-08395321547904
Pubmed

Serum pepsinogen I/II ratio is correlated with albuminuria in patients with type 2 diabetes.

PGA4 PGA5 PGA3

7.88e-08495323047493
Pubmed

Pepsinogens, progastricsins, and prochymosins: structure, function, evolution, and development.

PGA4 PGA5 PGA3

7.88e-08495311915945
Pubmed

Pepsinogen A and C serum levels in relation to acute NSAID-associated mucosal lesions in healthy volunteers.

PGA4 PGA5 PGA3

7.88e-0849538322031
Pubmed

Transcription factor SOX2 up-regulates stomach-specific pepsinogen A gene expression.

PGA4 PGA5 PGA3

7.88e-08495317136346
Pubmed

Pepsinogen A, pepsinogen C, and gastrin as markers of atrophic chronic gastritis in European dyspeptics.

PGA4 PGA5 PGA3

7.88e-08495312698190
Pubmed

A human MAP kinase interactome.

KMT2C RIF1 CRTC3 SETX VWF N4BP2 NAV3 NAV2 EPB41L3 MUC1 OBI1

9.63e-08486951120936779
Pubmed

Accuracy and cut-off values of pepsinogens I, II and gastrin 17 for diagnosis of gastric fundic atrophy: influence of gastritis.

PGA4 PGA5 PGA3

1.97e-07595322066020
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

5.12e-075795532633719
Pubmed

Abnormal neocortex arealization and Sotos-like syndrome-associated behavior in Setd2 mutant mice.

SP8 PCDHB5 PCDHB8 PCDHGB4

1.02e-062895433523829
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

1.24e-066895511230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

1.66e-067295510380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

1.90e-067495510817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

2.31e-067795510835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

2.80e-068095510716726
Pubmed

An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells.

PGA4 FOXP4 PGA5 PGA3

3.22e-063795421362171
Pubmed

Protocadherins.

PCDHB5 PCDHB8 PCDHB4

5.54e-061395312231349
Pubmed

Nucleotide sequence comparison of five human pepsinogen A (PGA) genes: evolution of the PGA multigene family.

PGA4 PGA5

7.38e-0629522714789
Pubmed

Activation of human pepsinogens.

PGA4 PGA5

7.38e-0629523197840
Pubmed

Linking ATM Promoter Methylation to Cell Cycle Protein Expression in Brain Tumor Patients: Cellular Molecular Triangle Correlation in ATM Territory.

RB1 ATM

7.38e-06295225159481
Pubmed

Crystal structure of human pepsin and its complex with pepstatin.

PGA4 PGA5

7.38e-0629527663352
Pubmed

Exome sequencing identifies nonsegregating nonsense ATM and PALB2 variants in familial pancreatic cancer.

ATM PALB2

7.38e-06295223561644
Pubmed

Isolation of human, swine, and rat prepepsinogens and calf preprochymosin, and determination of the primary structures of their NH2-terminal signal sequences.

PGA4 PGA5

7.38e-0629522415509
Pubmed

Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.

PCDHB5 PCDHB8 PCDHB4

1.31e-051795318279309
Pubmed

Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling.

PGA4 PGA5 PGA3

1.56e-051895336057966
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB5 PCDHB8 PCDHB4

2.18e-052095311322959
Pubmed

Nck-1 interacts with PKR and modulates its activation by dsRNA.

NCK1 EIF2AK2

2.21e-05395218835251
Pubmed

Clinicopathological Features and Outcomes in Individuals with Breast Cancer and ATM, CHEK2, or PALB2 Mutations.

ATM PALB2

2.21e-05395232996020
Pubmed

Role of Dok1 in cell signaling mediated by RET tyrosine kinase.

DOK1 NCK1

2.21e-05395212087092
Pubmed

CLASP2-dependent microtubule capture at the neuromuscular junction membrane requires LL5β and actin for focal delivery of acetylcholine receptor vesicles.

CLASP2 PHLDB2

2.21e-05395225589673
Pubmed

Protein phosphatase 1 acts as a RIF1 effector to suppress DSB resection prior to Shieldin action.

RIF1 SHLD1

2.21e-05395234260925
Pubmed

Involvement of multiple taste receptors in umami taste: analysis of gustatory nerve responses in metabotropic glutamate receptor 4 knockout mice.

TAS1R1 GRM4

2.21e-05395225529865
Pubmed

Factors that differentiate cancer risk management decisions among females with pathogenic/likely pathogenic variants in PALB2, CHEK2, and ATM.

ATM PALB2

2.21e-05395237515473
Pubmed

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.

ATM PALB2

2.21e-05395227595995
Pubmed

MUC1-C Oncoprotein Interacts Directly with ATM and Promotes the DNA Damage Response to Ionizing Radiation.

ATM MUC1

2.21e-05395220865059
Pubmed

c-Abl phosphorylates Dok1 to promote filopodia during cell spreading.

DOK1 NCK1

2.21e-05395215148308
Pubmed

CLASPs attach microtubule plus ends to the cell cortex through a complex with LL5beta.

CLASP2 PHLDB2

2.21e-05395216824950
Pubmed

Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.

NAV3 NAV2

2.21e-05395212079279
Pubmed

Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.

NAV3 NAV2

2.21e-05395215158073
Cytoband5q31

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

4.37e-061159555q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

4.01e-04298955chr5q31
GeneFamilyClustered protocadherins

PCDHB5 PCDHB8 PCDHGB4 PCDHB4 PCDHA3

3.32e-066465520
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAPN9 NAV2 ITLN2 SCD5 EPB41L3 PHLDB2 PDZD2

1.44e-071859571c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellLAM-Epithelial-AT1|Epithelial / Condition, Lineage and Cell class

NAV2 ITLN2 PLEKHH2 SCD5 EPB41L3 VSIR PHLDB2

1.79e-071919573457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCellnucseq-Epithelial-Epithelial_Alveolar|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTPRK MICAL2 AFF3 NAV2 MUC1 DNAH14 PDZD2

1.99e-0719495753f3e49e91b1096f3226010e2de767efb490dfe4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 ATP6V0D1 AFF3 UQCRC2 TBR1 SCD5 EPB41L3

2.45e-0720095744bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

C14orf132 MICAL2 PER1 CPE EPB41L3 XKR5

2.01e-061749561779e67382cb2644534ffb5b9b8f28d32935f4ea
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CAPN9 NAV2 ITLN2 SCD5 PHLDB2 PDZD2

2.36e-061799564f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

CAPN9 MICAL2 NAV2 SCD5 DNAH14 PHLDB2

2.68e-06183956942530449e9c6583705eeb8f6f12621daea57252
ToppCellwk_08-11-Hematologic-Myeloid-Neutrophil|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 ADGRG3 TAGAP PGA5 VSIR PGA3

2.86e-06185956655fb705d7a029844ecb4f6a53e948e37ee81006
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MICAL2 NAV2 SCD5 EPB41L3 PHLDB2 PDZD2

3.33e-0619095630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

PTPRK MICAL2 AFF3 NAV2 DNAH14 PDZD2

3.54e-06192956efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

TRIM33 PTPRK ZFYVE16 N4BP2 CHML EIF2AK2

3.65e-06193956abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C RIF1 NAV2 CPE EPB41L3 PHLDB2

3.87e-061959563e519cffa6144a62b06124642a14c9ff39b76554
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PTPRK MICAL2 NAV2 MUC1 DNAH14 PDZD2

3.87e-061959569406866f99555198a9be311fbd65751b70f35446
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C RIF1 NAV2 CPE EPB41L3 PHLDB2

3.87e-061959567796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellControl-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

TTYH2 CDH23 CHKA EPB41L3 LILRB1 VSIR

3.87e-06195956b4444b67a709e82b8e2ee510924c3152cb88b051
ToppCellILEUM-non-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

C14orf132 VWF PCDH19 CDH23 CPE EPB41L3

4.11e-06197956143607d195c8aa2b94d995af0b2ef38582565611
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPRK MICAL2 AFF3 CHKA DNAH14 PDZD2

4.35e-061999568587bd98de7767a575088afbea07a1feb4516b9b
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

FOXP4 ATP6V0D1 AFF3 CPE TBR1 EPB41L3

4.48e-06200956e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAPN9 C14orf132 NAV2 ITLN2 SCD5 PHLDB2

4.48e-06200956c6f211bbadd0c9be776c58807249e06764df47dc
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CAPN9 C14orf132 NAV2 ITLN2 SCD5 PHLDB2

4.48e-062009565f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CAPN9 C14orf132 NAV2 ITLN2 SCD5 PHLDB2

4.48e-06200956e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellControl-NK|World / Disease group and Cell class

ADGRG3 AFF3 NAV2 CPE CHKA

1.39e-05143955fe08adc9472dfd4242497d6c614d0490713261da
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

LPIN3 PRUNE2 INTU PCDH19 SUCNR1

2.12e-051569559a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPIN3 VWF MICAL2 TAS1R1 CPE

2.94e-05167955f01b96173deda0239fa482989873cf308e49d48c
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LPIN3 VWF MICAL2 TAS1R1 CPE

2.94e-051679555fc85a05124cd2324e1b8ff940193880f83cd8af
ToppCellControl|World / group, cell type (main and fine annotations)

PTPRK MICAL2 AFF3 NAV2 PDZD2

3.02e-05168955a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

VWF NAV2 SCD5 PHLDB2 PDZD2

3.20e-05170955e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellfacs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPIN3 PRUNE2 RBM19 TTYH2 NAV3

3.38e-05172955b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCellfacs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPIN3 PRUNE2 RBM19 TTYH2 NAV3

3.38e-051729552f1673fcb2356684d60871debb0f159aec553a1c
ToppCellfacs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF N4BP2 PCDHB8 CPE PKHD1L1

3.38e-05172955f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCellfacs-Heart-LV-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF N4BP2 PCDHB8 CPE PKHD1L1

3.38e-051729556ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PTPRK CAPS2 PLEKHH2 DNAH14 PHLDB2

3.57e-05174955ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

NAV2 SCD5 EPB41L3 PHLDB2 PDZD2

3.57e-05174955548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN9 MICAL2 AFF3 NAV3 CDH23

3.67e-05175955795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellAT1-AT2_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

MICAL2 ITLN2 SCD5 CDH3 PHLDB2

3.67e-051759559a95ab5c361ebaa8747983c5a0d69025682a19ad
ToppCellCOVID-19-Epithelial_cells-AT1|COVID-19 / group, cell type (main and fine annotations)

MICAL2 NAV2 SCD5 MUC1 PDZD2

4.09e-05179955a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell3'-Adult-Appendix-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

N4BP2 RBM19 ZBTB22 CDH23 SCD5

4.09e-051799552285e3a9018a60d7f6e974fee46b6f61d39aa76f
ToppCell3'-Adult-Appendix-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

N4BP2 RBM19 ZBTB22 CDH23 SCD5

4.09e-051799550b0f27d7c5cc5ae7618d887dcfa7219df8ff1935
ToppCell3'-Adult-Appendix-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

N4BP2 RBM19 ZBTB22 CDH23 SCD5

4.09e-0517995563bc819df62b1f8f37bf1f17bdd4fcc161886923
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VWF MICAL2 PCDHB4 CPE PKHD1L1

4.31e-051819552c44c41b4e8a75ebdbaeb0c6cc5a03f17c44758c
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAV2 SCD5 CHKA EPB41L3 PHLDB2

4.31e-05181955b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAV2 SCD5 CHKA EPB41L3 GRM4

4.42e-05182955573771130247e869e4e58f22d4a1cb31989635cf
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL1 PLEKHH2 SCD5 KIF13A PDZD2

4.42e-05182955a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAV2 SCD5 CHKA EPB41L3 GRM4

4.42e-051829556cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KLHL1 PLEKHH2 SCD5 KIF13A PDZD2

4.42e-05182955831b5ce46b41efe01c4db6016c2f43148611373d
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CAPN9 C14orf132 MICAL2 NAV2 SCD5

4.54e-051839557b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CAPN9 C14orf132 ITLN2 PLEKHH2 PHLDB2

4.54e-051839556821dca076318115d360ff426eb1218cfe104063
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

PTPRK MICAL2 AFF3 MUC1 PDZD2

4.66e-05184955369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MICAL2 NAV2 SCD5 PHLDB2 PDZD2

4.66e-0518495557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

CAPN9 ITLN2 SCD5 PHLDB2 PDZD2

4.66e-05184955561592edc3083fad41b91811151b442207c65dd9
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MICAL2 NAV2 SCD5 PHLDB2 PDZD2

4.66e-05184955d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHKA1 ADGRG3 PCDHB5 C19orf44 CPE

4.78e-051859556a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCellControl-Epithelial_alveolar|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAV2 SCD5 EPB41L3 MUC1 PHLDB2

4.78e-051859553937e026add96a396122139daf8011cfbc60e75c
ToppCelldroplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHKA1 ADGRG3 PCDHB5 C19orf44 CPE

4.78e-0518595564791056cdbb739136dbef08f4b16e2b5427faad
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXP4 NAV2 CHKA EPB41L3 PHLDB2

4.91e-051869554e94158db52df41d71e67b02b9895a358eebee0f
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAV2 SCD5 CHKA EPB41L3 PHLDB2

4.91e-051869553aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MICAL2 NAV2 MTRR CDH3 DNAH14

4.91e-05186955acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TRIM33 ZFYVE16 PER1 ATM CHML

5.03e-051879550099def970fbc828756fbf853eca2ce77b8cd342
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FOXP4 NAV2 CHKA EPB41L3 PHLDB2

5.03e-0518795558d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCellControl-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

ITLN2 SCD5 EPB41L3 VSIR PHLDB2

5.03e-051879553a032432f780525f4f4c2a358897d9989b1ecae7
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 KLHL1 VWF CPE PHLDB2

5.16e-051889554ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRG3 KLHL1 VWF CPE PHLDB2

5.16e-05188955e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

PTPRK MICAL2 NAV2 MUC1 PDZD2

5.16e-05188955c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 TTYH2 NAV2 CPE EPB41L3

5.16e-05188955a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

PTPRK MICAL2 MUC1 DNAH14 PDZD2

5.16e-05188955707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellwk_08-11-Hematologic-Myeloid-S100A12-hi_cla._mono.|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 TAGAP PGA5 LILRB1 VSIR

5.43e-05190955b8c131020d20005cd9f23d26312196f62c958074
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MICAL2 AFF3 NAV3 CDH23 CPE

5.56e-051919552c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF MICAL2 PER1 CPE PKHD1L1

5.56e-051919554bfdf44d4402a42530d30c89d94946acdda4321b
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 TTYH2 NAV2 CPE EPB41L3

5.56e-051919553387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellChildren_(3_yrs)-Epithelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

PTPRK MICAL2 AFF3 DNAH14 PDZD2

5.56e-05191955e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

PTPRK MICAL2 NAV2 DNAH14 PDZD2

5.70e-05192955499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

PTPRK MICAL2 AFF3 MTRR PDZD2

5.70e-0519295558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PTPRK MICAL2 MTRR DNAH14 PDZD2

5.70e-05192955fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MICAL2 AFF3 NAV3 NAV2 CPE

5.84e-0519395509a9ab029f01234459a88e3e994fe90ef4cbb8c6
ToppCellwk_08-11-Hematologic-Myeloid-CX3CR1+_Mac|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PGA4 PGA5 LILRB1 VSIR PGA3

5.84e-05193955afc20433b5abc9b430751a2aa8d93b0fd136a888
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

TTYH2 CHKA EPB41L3 LILRB1 VSIR

5.84e-051939553479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2|Adult / Lineage, Cell type, age group and donor

PTPRK MICAL2 AFF3 MTRR PDZD2

5.84e-05193955738f4f0a9ddde2432b429ab46838e353b1790589
ToppCellLA|World / Chamber and Cluster_Paper

PRUNE2 AFF3 NAV2 PLEKHH2 EPB41L3

5.84e-05193955d4bf89437216baf489ea0239136dcedf3b6714af
ToppCellfacs-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 RPN2 SRPK2 CPE EPB41L3

5.84e-0519395515c86e20b97b6983410b36d308cddff56d141c98
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV3 NAV2 CDH23 PLEKHH2 PHLDB2

5.99e-05194955e93de9428c986b8943fc169258847c650cfab0e5
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH2 LAMP2 CLASP2 SCD5 EPB41L3

5.99e-0519495561b59f8e2c68851d827b058cf03904f8125e8047
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTYH2 CDH23 EPB41L3 LILRB1 VSIR

5.99e-05194955de9c7c602d886d0cd8bbd1d7e7744f84df951238
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-non-classical_monocyte-Non-classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TTYH2 CDH23 EPB41L3 LILRB1 VSIR

5.99e-0519495549441ca0a8fa34cb847fecbb4b809dd01d879ebb
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGA4 RB1 SUCNR1 EPB41L3 PGA5

5.99e-0519495548c37251518f96524807b5bd1bbc2820637666ad
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGA4 RB1 SUCNR1 EPB41L3 PGA5

5.99e-051949557b6a34d1f8922b71dcc931421666c1822cec8345
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

ITLN2 KIF13A MUC1 PHLDB2 EVI5L

5.99e-0519495588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

ITLN2 KIF13A MUC1 PHLDB2 EVI5L

5.99e-05194955a71728202493d4858342ea2756ea281cd0d99a3a
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PGA4 RB1 SUCNR1 EPB41L3 PGA5

5.99e-05194955435406ebe626c702f7d5a99a3d68ee85aa09be95
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CAPN9 C14orf132 SCD5 EPB41L3 PHLDB2

6.14e-05195955a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellControl-Myeloid-ncMonocyte|Control / Disease state, Lineage and Cell class

TTYH2 CHKA EPB41L3 LILRB1 VSIR

6.14e-05195955fcb05948e7480dc53f06f3fc9b9c3fc129874edd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MICAL2 AFF3 NAV3 NAV2 CPE

6.14e-051959553c3703f092b6fc1b7333426fb5e2823bfb74bb57
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF MICAL2 N4BP2 CPE PKHD1L1

6.29e-051969557d5eaed189aa6116f3799be010139fb675ec65e0
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ITLN2 SCD5 EPB41L3 VSIR PHLDB2

6.29e-051969556c99d29162848161c1f166a032320f87a5d5a631
ToppCellwk_15-18-Hematologic-Myeloid-Neutrophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PGA4 ADGRG3 PGA5 LILRB1 VSIR

6.29e-0519695536c01e0feea33448222010c21442b9fac671bd7d
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

C14orf132 MICAL2 NAV2 ITLN2 PHLDB2

6.29e-05196955eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAV3 CPE STAMBPL1 CDH3 XKR5

6.29e-05196955a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell3'_v3-Lung-Myeloid_Monocytic-Nonclassical_monocytes|Lung / Manually curated celltypes from each tissue

TTYH2 CDH23 EPB41L3 LILRB1 VSIR

6.29e-051969557fe97109a5a06b35fc081a85f341ea78da131323
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF MICAL2 N4BP2 CPE PKHD1L1

6.29e-05196955dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ITLN2 SCD5 EPB41L3 VSIR PHLDB2

6.44e-0519795569d5b8588046d119b5dff9a7fd6f49e97e00a5b7
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ITLN2 SCD5 EPB41L3 VSIR PHLDB2

6.44e-05197955e6cbfa267eb2e05b441fd034786faae07bb0e081
DrugMinaprine dihydrochloride [25953-17-7]; Down 200; 10.8uM; PC3; HG-U133A

TRIM33 SNX27 LAMP2 ATM UQCRC2 EPB41L3 CHML TOP2B

1.81e-061989581888_DN
Diseaseplatelet receptor Gi24 measurement

CDH23 VSIR

9.56e-055922EFO_0021877
Diseaseuterine fibroid measurement

PTPRK SRPK2 SHLD1

1.01e-0429923EFO_0009410
Diseaseinformation processing speed

CRTC3 TTYH2 CDH23 SHLD1

1.48e-0485924EFO_0004363
Diseasefemale breast cancer (is_implicated_in)

ATM PALB2

2.66e-048922DOID:0050671 (is_implicated_in)
Diseasepancreatic cancer (is_implicated_in)

MTRR ATM MUC1 PALB2

4.25e-04112924DOID:1793 (is_implicated_in)
Diseasesusceptibility to rubella infection measurement

INTU KIF13A PDZD2

5.80e-0452923EFO_0008418
Diseasemelanoma

EYS DLGAP4 SRPK2 ATM

6.63e-04126924EFO_0000756
DiseaseProstatic Neoplasms

KMT2C FOXP4 PTPRK RB1 RPN2 ATM EIF2AK2 PALB2

6.89e-04616928C0033578
DiseaseMalignant neoplasm of prostate

KMT2C FOXP4 PTPRK RB1 RPN2 ATM EIF2AK2 PALB2

6.89e-04616928C0376358
DiseaseNeoplasm of uncertain or unknown behavior of bladder

RB1 ATM

9.83e-0415922C0496930
DiseaseBenign neoplasm of bladder

RB1 ATM

9.83e-0415922C0154017
DiseaseCarcinoma in situ of bladder

RB1 ATM

9.83e-0415922C0154091
DiseaseC-X-C motif chemokine 16 measurement

CDH23 VSIR

1.42e-0318922EFO_0010911
DiseaseCarcinoma of bladder

RB1 ATM

1.42e-0318922C0699885
DiseaseParoxysmal atrial fibrillation

VWF SCN10A NAV2 PHLDB2

1.46e-03156924C0235480
Diseasefamilial atrial fibrillation

VWF SCN10A NAV2 PHLDB2

1.46e-03156924C3468561
DiseasePersistent atrial fibrillation

VWF SCN10A NAV2 PHLDB2

1.46e-03156924C2585653
DiseaseHereditary Non-Polyposis Colon Cancer Type 2

ATM PALB2

1.59e-0319922C1333991
DiseaseColorectal cancer, hereditary nonpolyposis, type 1

ATM PALB2

1.59e-0319922C2936783
DiseaseAtrial Fibrillation

VWF SCN10A NAV2 PHLDB2

1.61e-03160924C0004238
DiseaseParkinson's disease (is_implicated_in)

MTRR ATM EIF2AK2

1.75e-0376923DOID:14330 (is_implicated_in)
DiseaseAdenocarcinoma of prostate

ATM PALB2

1.76e-0320922C0007112
Diseaseinflammatory bowel disease (implicated_via_orthology)

EPB41L3 PDZD2

2.75e-0325922DOID:0050589 (implicated_via_orthology)
Diseasesystemic mastocytosis

EYS NAV3

2.75e-0325922MONDO_0016586
DiseaseHereditary Nonpolyposis Colorectal Neoplasms

ATM PALB2

2.98e-0326922C0009405

Protein segments in the cluster

PeptideGeneStartEntry
QDDGTFNSSYSLFSE

AFF3

41

P51826
SSDSDADELAAPYSQ

EVI5L

776

Q96CN4
DDEDNFSYIPLSTAN

CAPS2

76

Q9BXY5
ESLDSFTSNNGPFQY

ACBD5

321

Q5T8D3
QISYASTAPDLSDNS

GRM4

176

Q14833
STAPDLSDNSRYDFF

GRM4

181

Q14833
TNTAEDFYFSLEPSQ

ADGRG3

101

Q86Y34
INDNAPEFNSSEYSV

CDH23

341

Q9H251
ENDNSPRFDFTSDSA

CDH23

1411

Q9H251
NLSYGDNSDPALEAS

DLGAP4

761

Q9Y2H0
DSALPEESQLSYFNS

CHML

136

P26374
SASDQPSENLISYFN

RB1

391

P06400
ASDYLNFDSDSGQES

RBM19

166

Q9Y4C8
SDVNDNAPAFTQTSY

PCDHB5

441

Q9Y5E4
ATQQPFDVSAFNASY

UQCRC2

316

P22695
GDVNDNAPVFSQSSY

PCDHGB4

441

Q9UN71
NRFNPEDSSTYQSTS

PGA5

116

P0DJD9
SNDNNPVFSESTYAV

PCDH19

231

Q8TAB3
SENAALYFPQSDSGL

LPIN3

391

Q9BQK8
ADVNDNAPAFSQSEY

PCDHA3

446

Q9Y5H8
QSSYPDARDKNSAFN

KMT2C

1591

Q8NEZ4
FNPSEYQAITEASSN

EYS

1521

Q5T1H1
QALYPFSSSNDEELN

NCK1

196

P16333
SFPSAYDQQSSKDSR

PHKA1

1036

P46020
SNTDFSYQPGDAFSV

MTRR

301

Q9UBK8
NLQFNSSLEDPSTDY

MUC1

1051

P15941
AYSLLSASSEQDNPS

PER1

106

O15534
DAASYAANLTDSAEA

PDZD2

1051

O15018
SIPAQDSSFDLYDDS

NAV3

1501

Q8IVL0
STSYAQNLDFESSEG

OBI1

471

Q5W0B1
SALADPDQYNFSSSE

LAPTM4B

136

Q86VI4
FSYNTGDNTTFPDAE

LAMP2

116

P13473
NASYQAALAESSFPL

FOXP4

571

Q8IVH2
LFSYDSLDSPNSDDQ

PLEKHH2

511

Q8IVE3
NRFNPEDSSTYQSTS

PGA3

116

P0DJD8
SASPSAQQYDASSAV

INTU

451

Q9ULD6
SDVNDNAPAFTQTSY

PCDHB4

441

Q9Y5E5
SNSAYLSLDDDAFTA

PALB2

576

Q86YC2
NLFNDYPDSSVSDAN

ATM

856

Q13315
NEQTASFAPAYADLL

HOXB1

146

P14653
QDSLYSDPLDSTSAQ

DOK1

311

Q99704
LESSDYDPENSKNSS

EIF2AK2

341

P19525
SYLPAFQNDFENLST

CHKA

381

P35790
SAYSEDFENSPSLTA

C19orf44

466

Q9H6X5
SAFGANYSSQPLDES

CRTC3

121

Q6UUV7
PNEDFSTEYSLFNSS

C14orf132

21

Q9NPU4
AHEYSSSPDDAIFQS

CPE

266

P16870
TPNASNQTDSELYAF

DNAH14

3441

Q0VDD8
NTTSAFPYALLSNDN

IDUA

336

P35475
NYNTFGSAEAATSDD

ITLN2

131

Q8WWU7
SQYSDAFLAANTSLD

EMILIN3

606

Q9NT22
ADFPASNSSLFYSER

CAPN9

46

O14815
TSPFQAQLTDDSDIY

CDH3

576

P22223
DDDGYLSFPNLSETN

EPB41L3

601

Q9Y2J2
EAADFATNYQLPSLD

MICAL2

341

O94851
NFSPRYENHSATAES

PTPRK

826

Q15262
NRFNPEDSSTYQSTS

PGA4

116

P0DJD7
NDNAPAFTQTSYTLF

PCDHB8

446

Q9UN66
LDAASEASSEPDYNY

KIF13A

566

Q9H1H9
NYFVKDTSEAPSSSD

TRIM33

196

Q9UPN9
AASAYDTATDFAGNA

TBR1

496

Q16650
SQQSSHSADYSPADD

PRUNE2

506

Q8WUY3
NLFSFPSYSQKSEDD

TOP2B

1446

Q02880
VSTLQNDSAYDSNDP

TAGAP

301

Q8N103
SSPAADAQEENLYAA

LILRB1

521

Q8NHL6
TSQANPYSEGQFLDE

RIF1

1776

Q5UIP0
FSNAYAAAVSAVDPD

TAF2

106

Q6P1X5
SLSNADGQYDPYTDS

NAV2

1591

Q8IVL1
EAANYSSPQSYDSDS

NAV2

2456

Q8IVL1
YASNTPSGEFQTADE

SETX

21

Q7Z333
FPYSSDVDPDTSNLN

SHLD1

51

Q8IYI0
DYSASEFGLNFNPTT

SCD5

281

Q86SK9
SDDFDQASYVGTNPS

PHLDB2

351

Q86SQ0
AAAAAASSSPFANDY

SP8

111

Q8IXZ3
ASSSPFANDYSVFQA

SP8

116

Q8IXZ3
SQNTLSPSAFDYDTE

CLASP2

916

O75122
TLQQLYDFTSSEDAP

WDR90

731

Q96KV7
TVAFNDNRDPLSSYN

TAS1R1

436

Q7RTX1
QEGTLTSDPYDFANS

VWF

176

P04275
PSNVDSLFYAAQASQ

RPN2

81

P04844
LKTSDNPDFNYTSFD

SCN10A

326

Q9Y5Y9
SEDSSDQYLQAPNST

TBX22

426

Q9Y458
NSTFSPGDESYQESL

TTYH2

31

Q9BSA4
FADQPNKSDATNYAS

STAMBPL1

226

Q96FJ0
YPSSSQDSENITAAA

VSIR

181

Q9H7M9
LDEPNAESDYTYSSS

SRPK2

416

P78362
SASYSENRNQPVDSS

ZBTB44

211

Q8NCP5
DNLDPSDDSLGQSFY

SNX27

141

Q96L92
FYQTSVESTDFANAP

SERPINB4

126

P48594
NANSYFSSPTQRSDD

PKHD1L1

436

Q86WI1
TCNDFASSGDPNYNL

SUCNR1

171

Q9BXA5
YDDDDSAASTSFQPQ

ZNF207

116

O43670
NASPSLTASSQEDYE

TTLL9

341

Q3SXZ7
SYVSFASDQQDEAPT

XKR5

486

Q6UX68
RASENQSPSSSNYFS

ZBTB22

196

O15209
IDSTADPQVSFNSNY

ZFYVE16

691

Q7Z3T8
STDYGNFLANEASPL

ATP6V0D1

51

P61421
PQSDLDSSSSEEFYQ

KLHL1

176

Q9NR64
NSFNDSSEFINPDSS

N4BP2

171

Q86UW6