Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metalloaminopeptidase activity	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	1.30e-15	26	50	8	GO:0070006
GeneOntologyMolecularFunction	aminopeptidase activity	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	1.16e-13	43	50	8	GO:0004177
GeneOntologyMolecularFunction	metalloexopeptidase activity	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	7.21e-12	70	50	8	GO:0008235
GeneOntologyMolecularFunction	protein-glutamine gamma-glutamyltransferase activity	TGM1 TGM3 TGM6 F13A1 TGM5	1.00e-11	9	50	5	GO:0003810
GeneOntologyMolecularFunction	exopeptidase activity	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	2.90e-10	110	50	8	GO:0008238
GeneOntologyMolecularFunction	metallopeptidase activity	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	3.30e-08	200	50	8	GO:0008237
GeneOntologyMolecularFunction	peptide binding	LVRN NPFFR2 ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	8.31e-08	318	50	9	GO:0042277
GeneOntologyMolecularFunction	peptidase activity	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS USP32 PRSS51 SPPL2B ENPEP	4.99e-07	654	50	11	GO:0008233
GeneOntologyMolecularFunction	zinc ion binding	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	1.55e-03	891	50	8	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS FAXDC2 ENPEP	2.50e-03	1189	50	9	GO:0046914
GeneOntologyMolecularFunction	calcium channel activity	CATSPER4 TRPC4 TRPV4	4.14e-03	129	50	3	GO:0005262
GeneOntologyBiologicalProcess	peptide catabolic process	LVRN ANPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	6.50e-14	23	49	7	GO:0043171
GeneOntologyBiologicalProcess	peptide metabolic process	LVRN ANPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	1.08e-09	84	49	7	GO:0006518
GeneOntologyBiologicalProcess	peptide cross-linking	TGM1 TGM3 TGM6 F13A1 TGM5	4.76e-09	27	49	5	GO:0018149
GeneOntologyBiologicalProcess	regulation of blood pressure	RNPEP ERAP2 ERAP1 LNPEP GCGR ENPEP	2.00e-05	237	49	6	GO:0008217
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class I	ERAP2 ERAP1 LNPEP	1.26e-04	41	49	3	GO:0002474
GeneOntologyCellularComponent	cell surface	PLA2R1 ANPEP RNPEP LNPEP CD163L1 TRPC4 TRPV4 ITGA2B AQP4 ENPEP	2.54e-04	1111	50	10	GO:0009986
GeneOntologyCellularComponent	secretory granule	GALNS ANPEP RNPEP LNPEP CATSPER4 PRSS51 ITGA2B F13A1 FERMT3	5.97e-04	1014	50	9	GO:0030141
GeneOntologyCellularComponent	side of membrane	TGM3 ANPEP RNPEP CD163L1 ITGA2B SPPL2B AQP4 ENPEP	1.03e-03	875	50	8	GO:0098552
GeneOntologyCellularComponent	external side of plasma membrane	ANPEP RNPEP CD163L1 ITGA2B AQP4 ENPEP	1.43e-03	519	50	6	GO:0009897
GeneOntologyCellularComponent	platelet alpha granule	ITGA2B F13A1 FERMT3	1.44e-03	93	50	3	GO:0031091
GeneOntologyCellularComponent	secretory vesicle	GALNS ANPEP RNPEP LNPEP CATSPER4 PRSS51 ITGA2B F13A1 FERMT3	2.52e-03	1246	50	9	GO:0099503
Domain	Peptidase_M1	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	8.53e-19	12	51	8	IPR001930
Domain	Peptidase_M1	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	2.21e-18	13	51	8	PF01433
Domain	Peptidase_M1_N	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	2.21e-18	13	51	8	IPR014782
Domain	ERAP1-like_C_dom	LVRN ANPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	5.88e-18	8	51	7	IPR024571
Domain	ERAP1_C	LVRN ANPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	5.88e-18	8	51	7	PF11838
Domain	Transglut_N	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	PF00868
Domain	TRANSGLUTAMINASES	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	PS00547
Domain	Transglutaminase_N	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	IPR001102
Domain	Transglut_C	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	PF00927
Domain	-	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	3.90.260.10
Domain	Gln_gamma-glutamylTfrase_euk	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	IPR023608
Domain	Transglutaminase_AS	TGM1 TGM3 TGM6 F13A1 TGM5	1.55e-11	9	51	5	IPR013808
Domain	Transglutaminase_C	TGM1 TGM3 TGM6 F13A1 TGM5	3.10e-11	10	51	5	IPR008958
Domain	TGc	TGM1 TGM3 TGM6 F13A1 TGM5	5.66e-11	11	51	5	SM00460
Domain	Transglut_core	TGM1 TGM3 TGM6 F13A1 TGM5	5.66e-11	11	51	5	PF01841
Domain	Transglutaminase-like	TGM1 TGM3 TGM6 F13A1 TGM5	5.66e-11	11	51	5	IPR002931
Domain	ZINC_PROTEASE	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	2.27e-10	98	51	8	PS00142
Domain	Ig_E-set	TGM1 TGM3 TGM6 F13A1 TGM5	9.31e-06	104	51	5	IPR014756
Domain	TRP_channel	TRPC4 TRPV4	3.96e-04	11	51	2	IPR004729
Domain	Gal_Oxase/kelch_b-propeller	MEGF8 WDR6 FBXO42	5.60e-04	59	51	3	IPR011043
Domain	-	STARD9 AHSA1	1.78e-03	23	51	2	3.30.530.20
Domain	START-like_dom	STARD9 AHSA1	1.78e-03	23	51	2	IPR023393
Domain	Ion_trans_dom	CATSPER4 TRPC4 TRPV4	3.73e-03	114	51	3	IPR005821
Domain	Ion_trans	CATSPER4 TRPC4 TRPV4	3.73e-03	114	51	3	PF00520
Domain	F-box-like	FBXO16 FBXO42	6.43e-03	44	51	2	PF12937
Domain	-	MEGF8 FBXO42	7.61e-03	48	51	2	2.120.10.80
Domain	FBOX	FBXO16 FBXO42	8.88e-03	52	51	2	SM00256
Domain	Kelch-typ_b-propeller	MEGF8 FBXO42	9.90e-03	55	51	2	IPR015915
Pathway	KEGG_RENIN_ANGIOTENSIN_SYSTEM	ANPEP LNPEP ENPEP	1.01e-05	17	36	3	M17636
Pubmed	Local expression of AP/AngIV/IRAP and effect of AngIV on glucose-induced epithelial transport in human jejunal mucosa.	ANPEP RNPEP LNPEP ENPEP	4.44e-12	4	52	4	26311161
Pubmed	Biochemical and enzymatic properties of the M1 family of aminopeptidases involved in the regulation of blood pressure.	ANPEP ERAP1 LNPEP ENPEP	4.44e-12	4	52	4	17999179
Pubmed	Knocking-in the R142C mutation in transglutaminase 1 disrupts the stratum corneum barrier and postnatal survival of mice.	TGM1 TGM3 TGM6 TGM5	6.65e-11	6	52	4	22258055
Pubmed	Evolution of transglutaminase genes: identification of a transglutaminase gene cluster on human chromosome 15q15. Structure of the gene encoding transglutaminase X and a novel gene family member, transglutaminase Z.	TGM1 TGM3 TGM6 TGM5	1.55e-10	7	52	4	11390390
Pubmed	HIV-1 gp120-dependent induction of apoptosis in antigen-specific human T cell clones is characterized by 'tissue' transglutaminase expression and prevented by cyclosporin A.	TGM1 TGM3 TGM6 TGM5	3.10e-10	8	52	4	7906657
Pubmed	Human-immunodeficiency-virus transmembrane glycoprotein gp41 is an amino acceptor and donor substrate for transglutaminase in vitro.	TGM1 TGM3 TGM6 TGM5	3.10e-10	8	52	4	7688299
Pubmed	Genetic associations and functional characterization of M1 aminopeptidases and immune-mediated diseases.	ERAP2 ERAP1 NPEPPS	3.15e-09	3	52	3	25142031
Pubmed	Plasma renin-angiotensin system-regulating aminopeptidase activities are modified in early stage Alzheimer's disease and show gender differences but are not related to apolipoprotein E genotype.	ANPEP RNPEP LNPEP	3.15e-09	3	52	3	23500679
Pubmed	Regulation of the human leukocyte-derived arginine aminopeptidase/endoplasmic reticulum-aminopeptidase 2 gene by interferon-gamma.	ERAP2 ERAP1 LNPEP	3.15e-09	3	52	3	15691326
Pubmed	Genetic variation in the epidermal transglutaminase genes is not associated with atopic dermatitis.	TGM1 TGM3 TGM5	3.15e-09	3	52	3	23189155
Pubmed	Cell-Specific and Variant-Linked Alterations in Expression of ERAP1, ERAP2, and LNPEP Aminopeptidases in Psoriasis.	ERAP2 ERAP1 LNPEP	3.15e-09	3	52	3	36716917
Pubmed	Probing the S1 specificity pocket of the aminopeptidases that generate antigenic peptides.	ERAP2 ERAP1 LNPEP	3.15e-09	3	52	3	21314638
Pubmed	The oxytocinase subfamily of M1 aminopeptidases.	ERAP2 ERAP1 LNPEP	3.15e-09	3	52	3	16054015
Pubmed	A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.	ERAP2 ERAP1 LNPEP	1.26e-08	4	52	3	24957906
Pubmed	The ERAP2 gene is associated with preeclampsia in Australian and Norwegian populations.	LVRN ERAP2 ERAP1 LNPEP	2.61e-08	21	52	4	19578876
Pubmed	Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life.	TGM1 TGM3 TGM5	3.75e-07	10	52	3	26975724
Pubmed	Melanopsin signalling in mammalian iris and retina.	TRPC4 TRPV4 CRY1	8.92e-07	13	52	3	22051675
Pubmed	Evaluation of AQP4/TRPV4 Channel Co-expression, Microvessel Density, and its Association with Peritumoral Brain Edema in Intracranial Meningiomas.	TRPV4 AQP4	2.19e-06	2	52	2	33538957
Pubmed	Altered expression of endoplasmic reticulum aminopeptidases ERAP1 and ERAP2 in transformed non-lymphoid human tissues.	ERAP2 ERAP1	2.19e-06	2	52	2	18393273
Pubmed	AQP4 regulates ferroptosis and oxidative stress of Muller cells in diabetic retinopathy by regulating TRPV4.	TRPV4 AQP4	2.19e-06	2	52	2	38735619
Pubmed	Genomic organization of the human adipocyte-derived leucine aminopeptidase gene and its relationship to the placental leucine aminopeptidase/oxytocinase gene.	ERAP2 ERAP1	2.19e-06	2	52	2	11481040
Pubmed	Structural basis for the coordinated regulation of transglutaminase 3 by guanine nucleotides and calcium/magnesium.	TGM1 TGM3	2.19e-06	2	52	2	14645372
Pubmed	Association of an ERAP1 ERAP2 haplotype with familial ankylosing spondylitis.	ERAP2 ERAP1	2.19e-06	2	52	2	19433412
Pubmed	The crystal structure of human endoplasmic reticulum aminopeptidase 2 reveals the atomic basis for distinct roles in antigen processing.	ERAP2 ERAP1	2.19e-06	2	52	2	22106953
Pubmed	The ER Aminopeptidases, ERAP1 and ERAP2, synergize to self-modulate their respective activities.	ERAP2 ERAP1	2.19e-06	2	52	2	36569828
Pubmed	Concerted peptide trimming by human ERAP1 and ERAP2 aminopeptidase complexes in the endoplasmic reticulum.	ERAP2 ERAP1	2.19e-06	2	52	2	15908954
Pubmed	Investigation of mouse amniotic fluid for stimulating ability of keratinocyte differentiation depending on the fetal stage.	TGM1 TGM3	2.19e-06	2	52	2	34390735
Pubmed	Genetic diversity at endoplasmic reticulum aminopeptidases is maintained by balancing selection and is associated with natural resistance to HIV-1 infection.	ERAP2 ERAP1	2.19e-06	2	52	2	20843824
Pubmed	The speed of swelling kinetics modulates cell volume regulation and calcium signaling in astrocytes: A different point of view on the role of aquaporins.	TRPV4 AQP4	2.19e-06	2	52	2	26413835
Pubmed	Differential expression of transglutaminase genes in patients with chronic periodontitis.	TGM1 TGM3	2.19e-06	2	52	2	24112124
Pubmed	Study of asparagine 353 in aminopeptidase A: characterization of a novel motif (GXMEN) implicated in exopeptidase specificity of monozinc aminopeptidases.	ANPEP ENPEP	2.19e-06	2	52	2	11724556
Pubmed	Placental leucine aminopeptidase efficiently generates mature antigenic peptides in vitro but in patterns distinct from endoplasmic reticulum aminopeptidase 1.	ERAP1 LNPEP	2.19e-06	2	52	2	20592285
Pubmed	Increased APN/CD13 and acid aminopeptidase activities in head and neck squamous cell carcinoma.	ANPEP ENPEP	2.19e-06	2	52	2	19373777
Pubmed	Synergy of endoplasmic reticulum aminopeptidase 1 and 2 (ERAP1 and ERAP2) polymorphisms in atopic dermatitis: Effects on disease prevalence.	ERAP2 ERAP1	2.19e-06	2	52	2	33309189
Pubmed	Antigenic peptide trimming by ER aminopeptidases--insights from structural studies.	ERAP2 ERAP1	2.19e-06	2	52	2	23545452
Pubmed	ERAP1-ERAP2 dimers trim MHC I-bound precursor peptides; implications for understanding peptide editing.	ERAP2 ERAP1	2.19e-06	2	52	2	27514473
Pubmed	Genetic Variants in ERAP1 and ERAP2 Associated With Immune-Mediated Diseases Influence Protein Expression and the Isoform Profile.	ERAP2 ERAP1	2.19e-06	2	52	2	29108111
Pubmed	A Comparative Review of Pregnancy and Cancer and Their Association with Endoplasmic Reticulum Aminopeptidase 1 and 2.	ERAP2 ERAP1	2.19e-06	2	52	2	36834865
Pubmed	The Differential Expression of ERAP1/ERAP2 and Immune Cell Activation in Pre-eclampsia.	ERAP2 ERAP1	2.19e-06	2	52	2	32210971
Pubmed	The association of ERAP1 and ERAP2 single nucleotide polymorphisms and their haplotypes with psoriasis vulgaris is dependent on the presence or absence of the HLA-C*06:02 allele and age at disease onset.	ERAP2 ERAP1	2.19e-06	2	52	2	29183862
Pubmed	An allelic variant in the intergenic region between ERAP1 and ERAP2 correlates with an inverse expression of the two genes.	ERAP2 ERAP1	2.19e-06	2	52	2	29991817
Pubmed	Serum cytokine receptors in ankylosing spondylitis: relationship to inflammatory markers and endoplasmic reticulum aminopeptidase polymorphisms.	ERAP2 ERAP1	2.19e-06	2	52	2	20595269
Pubmed	Separate effects of the ankylosing spondylitis associated ERAP1 and ERAP2 aminopeptidases determine the influence of their combined phenotype on the HLA-B*27 peptidome.	ERAP2 ERAP1	2.19e-06	2	52	2	28063628
Pubmed	ERAP1-ERAP2 dimerization increases peptide-trimming efficiency.	ERAP2 ERAP1	2.19e-06	2	52	2	24928998
Pubmed	The absence of AQP4/TRPV4 complex substantially reduces acute cytotoxic edema following ischemic injury.	TRPV4 AQP4	2.19e-06	2	52	2	36568889
Pubmed	Distinct molecular mechanisms leading to deficient expression of ER-resident aminopeptidases in melanoma.	ERAP2 ERAP1	2.19e-06	2	52	2	20419298
Pubmed	TRPV4 channels augment macrophage activation and ventilator-induced lung injury.	TRPC4 TRPV4	2.19e-06	2	52	2	20562229
Pubmed	Pan-Cancer Analysis of the TRP Family, Especially TRPV4 and TRPC4, and Its Expression Correlated with Prognosis, Tumor Microenvironment, and Treatment Sensitivity.	TRPC4 TRPV4	2.19e-06	2	52	2	36830651
Pubmed	Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and gluten ataxia.	TGM3 TGM6	2.19e-06	2	52	2	20300788
Pubmed	Ectopic transglutaminase 1 and 3 expression accelerating keratinization in oral lichen planus.	TGM1 TGM3	2.19e-06	2	52	2	30213231
Pubmed	TRPV4 and AQP4 Channels Synergistically Regulate Cell Volume and Calcium Homeostasis in Retinal Müller Glia.	TRPV4 AQP4	2.19e-06	2	52	2	26424896
Pubmed	The ERAP gene is associated with HCV chronic infection in a Chinese Han population.	ERAP2 ERAP1	2.19e-06	2	52	2	29037997
Pubmed	ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum.	ERAP2 ERAP1	2.19e-06	2	52	2	17088086
Pubmed	Comparative expression profiling for human endoplasmic reticulum-resident aminopeptidases 1 and 2 in normal kidney versus distinct renal cell carcinoma subtypes.	ERAP2 ERAP1	2.19e-06	2	52	2	23696916
Pubmed	Genetic association of ERAP1 and ERAP2 with eclampsia and preeclampsia in northeastern Brazilian women.	ERAP2 ERAP1	2.19e-06	2	52	2	33762660
Pubmed	Polymorphisms in endoplasmic reticulum aminopeptidase genes are associated with cervical cancer risk in a Chinese Han population.	ERAP2 ERAP1	2.19e-06	2	52	2	32321463
Pubmed	Functionally distinct ERAP1 and ERAP2 are a hallmark of HLA-A29-(Birdshot) Uveitis.	ERAP2 ERAP1	2.19e-06	2	52	2	30215709
Pubmed	TRPV4-AQP4 interactions 'turbocharge' astroglial sensitivity to small osmotic gradients.	TRPV4 AQP4	2.19e-06	2	52	2	26760501
Pubmed	Evaluation of role of angiotensin III and aminopeptidases in prostate cancer cells.	ANPEP ENPEP	2.19e-06	2	52	2	18677709
Pubmed	The role of LNPEP and ANPEP gene polymorphisms in the pathogenesis of pre-eclampsia.	ANPEP LNPEP	2.19e-06	2	52	2	32619880
Pubmed	Isolation of a cDNA encoding a novel member of the transglutaminase gene family from human keratinocytes. Detection and identification of transglutaminase gene products based on reverse transcription-polymerase chain reaction with degenerate primers.	TGM3 TGM5	2.19e-06	2	52	2	9452468
Pubmed	The ER aminopeptidase ERAP1 enhances or limits antigen presentation by trimming epitopes to 8-9 residues.	ERAP2 ERAP1	2.19e-06	2	52	2	12436110
Pubmed	An IFN-gamma-induced aminopeptidase in the ER, ERAP1, trims precursors to MHC class I-presented peptides.	ERAP2 ERAP1	2.19e-06	2	52	2	12436109
Pubmed	ERAP1-ERAP2 haplotypes are associated with ankylosing spondylitis in Polish patients.	ERAP2 ERAP1	2.19e-06	2	52	2	30794838
Pubmed	An aquaporin-4/transient receptor potential vanilloid 4 (AQP4/TRPV4) complex is essential for cell-volume control in astrocytes.	TRPV4 AQP4	2.19e-06	2	52	2	21262839
Pubmed	Expression of endoplasmic reticulum aminopeptidases in EBV-B cell lines from healthy donors and in leukemia/lymphoma, carcinoma, and melanoma cell lines.	ERAP2 ERAP1	2.19e-06	2	52	2	16585582
Pubmed	Hypothermia increases aquaporin 4 (AQP4) plasma membrane abundance in human primary cortical astrocytes via a calcium/transient receptor potential vanilloid 4 (TRPV4)- and calmodulin-mediated mechanism.	TRPV4 AQP4	2.19e-06	2	52	2	28925524
Pubmed	Analysis of 47 Non-MHC Ankylosing Spondylitis Susceptibility Loci Regarding Associated Variants across Whites and Han Chinese.	ERAP1 NPEPPS	6.57e-06	3	52	2	31523044
Pubmed	TRPV4 channels contribute to calcium transients in astrocytes and neurons during peri-infarct depolarizations in a stroke model.	TRPV4 AQP4	6.57e-06	3	52	2	28639721
Pubmed	ERAP1 and ERAP2 Gene Variations Influence the Risk of Psoriatic Arthritis in Romanian Population.	ERAP2 ERAP1	6.57e-06	3	52	2	28083616
Pubmed	ERAP1/ERAP2 and RUNX3 polymorphisms are not associated with ankylosing spondylitis susceptibility in Chinese Han.	ERAP2 ERAP1	6.57e-06	3	52	2	29480940
Pubmed	Gene disruption of tissue transglutaminase.	TGM1 TGM3	6.57e-06	3	52	2	11113189
Pubmed	ERAP1, ERAP2, and Two Copies of HLA-Aw19 Alleles Increase the Risk for Birdshot Chorioretinopathy in HLA-A29 Carriers.	ERAP2 ERAP1	6.57e-06	3	52	2	34727153
Pubmed	Hornerin is a component of the epidermal cornified cell envelopes.	TGM1 TGM3	6.57e-06	3	52	2	21282207
Pubmed	SPINK5 and Netherton syndrome: novel mutations, demonstration of missing LEKTI, and differential expression of transglutaminases.	TGM1 TGM3	6.57e-06	3	52	2	15304086
Pubmed	Identification of 33 polymorphisms in the adipocyte-derived leucine aminopeptidase (ALAP) gene and possible association with hypertension.	ERAP1 LNPEP	6.57e-06	3	52	2	11857741
Pubmed	ERAP1 and ERAP2 Haplotypes Influence Suboptimal HLA-B*27:05-Restricted Anti-Viral CD8+ T Cell Responses Cross-Reactive to Self-Epitopes.	ERAP2 ERAP1	6.57e-06	3	52	2	37686141
Pubmed	Mutant huntingtin protein: a substrate for transglutaminase 1, 2, and 3.	TGM1 TGM3	6.57e-06	3	52	2	15715085
Pubmed	Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.	ERAP2 ERAP1	6.57e-06	3	52	2	24223975
Pubmed	Low prevalence of IgA anti-transglutaminase 1, 2, and 3 autoantibodies in children with atopic dermatitis.	TGM1 TGM3	6.57e-06	3	52	2	24885370
Pubmed	Expression of Transglutaminase in Foreskin of Children with Balanitis Xerotica Obliterans.	TGM1 TGM3	6.57e-06	3	52	2	27649154
Pubmed	Direct interaction of kindlin-3 with integrin αIIbβ3 in platelets is required for supporting arterial thrombosis in mice.	ITGA2B FERMT3	6.57e-06	3	52	2	24969775
Pubmed	Assessment of expression and specific activities of transglutaminases TG1, TG2, and FXIII-A during osteoclastogenesis.	TGM1 F13A1	6.57e-06	3	52	2	31786225
Pubmed	Impaired angiogenesis in aminopeptidase N-null mice.	ANPEP ENPEP	6.57e-06	3	52	2	17360568
Pubmed	The interplay between HLA-B27 and ERAP1/ERAP2 aminopeptidases: from anti-viral protection to spondyloarthritis.	ERAP2 ERAP1	6.57e-06	3	52	2	28759104
Pubmed	Altered Activity and Expression of Cytosolic Peptidases in Colorectal Cancer.	RNPEP NPEPPS	6.57e-06	3	52	2	26078706
Pubmed	Human inter-α-inhibitor is a substrate for factor XIIIa and tissue transglutaminase.	TGM6 F13A1	1.31e-05	4	52	2	21939789
Pubmed	ADAP interactions with talin and kindlin promote platelet integrin αIIbβ3 activation and stable fibrinogen binding.	ITGA2B FERMT3	1.31e-05	4	52	2	24523237
Pubmed	Agonist stimulation, talin-1, and kindlin-3 are crucial for α(IIb)β(3) activation in a human megakaryoblastic cell line, CMK.	ITGA2B FERMT3	1.31e-05	4	52	2	23022222
Pubmed	Platelet factor XIII and calpain negatively regulate integrin alphaIIbbeta3 adhesive function and thrombus growth.	ITGA2B F13A1	1.31e-05	4	52	2	15131115
Pubmed	Transglutaminase and clusterin induction during normal and abnormal limb development in the mouse.	TGM1 TGM3	1.31e-05	4	52	2	8828830
Pubmed	TGM1/3-mediated transamidation of Exo70 promotes tumor metastasis upon LKB1 inactivation.	TGM1 TGM3	1.31e-05	4	52	2	39146185
Pubmed	Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice.	TGM1 TGM3	1.31e-05	4	52	2	16465267
Pubmed	Interferon-gamma can stimulate post-proteasomal trimming of the N terminus of an antigenic peptide by inducing leucine aminopeptidase.	LNPEP NPEPPS	1.31e-05	4	52	2	9668046
Pubmed	Regulated expression of tissue transglutaminase in Swiss 3T3 fibroblasts: effects on the processing of fibronectin, cell attachment, and cell death.	TGM1 TGM3	1.31e-05	4	52	2	9511731
Pubmed	Two new proteases in the MHC class I processing pathway.	LNPEP NPEPPS	1.31e-05	4	52	2	11062501
Pubmed	Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses.	ANPEP ENPEP	1.31e-05	4	52	2	32199615
Pubmed	ZFP750 affects the cutaneous barrier through regulating lipid metabolism.	TGM1 TGM3 TGM5	1.38e-05	31	52	3	37115925
Pubmed	Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase).	TGM1 TGM3	2.19e-05	5	52	2	9448282
Pubmed	NF-kappaB, and not MYCN, regulates MHC class I and endoplasmic reticulum aminopeptidases in human neuroblastoma cells.	ERAP2 ERAP1	2.19e-05	5	52	2	20103633
Cytoband	5q15	ERAP2 ERAP1 LNPEP	1.31e-05	40	52	3	5q15
Cytoband	Ensembl 112 genes in cytogenetic band chr5q15	ERAP2 ERAP1 LNPEP	4.26e-05	59	52	3	chr5q15
Cytoband	15q15.2	STARD9 TGM5	1.49e-04	16	52	2	15q15.2
Cytoband	22q12.2	MTMR3 SFI1	2.00e-03	58	52	2	22q12.2
Cytoband	3p21.31	WDR6 ALS2CL	5.80e-03	100	52	2	3p21.31
Cytoband	Ensembl 112 genes in cytogenetic band chr20p13	TGM3 TGM6	8.65e-03	123	52	2	chr20p13
GeneFamily	Aminopeptidases\|CD molecules	LVRN ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	2.57e-18	17	36	8	104
GeneFamily	Transglutaminases	TGM1 TGM3 TGM6 F13A1 TGM5	2.94e-12	9	36	5	773
GeneFamily	Transient receptor potential cation channels	TRPC4 TRPV4	1.41e-03	28	36	2	249
GeneFamily	Cyclins\|F-boxes other	FBXO16 FBXO42	2.73e-03	39	36	2	560
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets-Platelets\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPFFR2 SI ITGA2B F13A1 FERMT3	9.42e-07	152	52	5	aff7d1127ef72be489477611c4decc53cc7632e3
ToppCell	LPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Platelets\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NPFFR2 SI ITGA2B F13A1 FERMT3	9.42e-07	152	52	5	0a99c91165e4d82fb8825fbdf3071c9a5445669d
ToppCell	ileum-Absorptive_Enterocytes\|ileum / shred on tissue and cell subclass	ANPEP SI ENPEP	1.50e-05	41	52	3	650cec538c6acd92f45d804b3c94248c6231aa21
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ALS2CL ENPEP TGM5	3.23e-05	155	52	4	90e629681a72baacc7981b82883866a487638dbc
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ALS2CL ENPEP TGM5	3.23e-05	155	52	4	e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ALS2CL ENPEP TGM5	3.23e-05	155	52	4	5a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ANPEP ALS2CL ENPEP	3.56e-05	159	52	4	fd7db2f7328cfefdc3ada2af91006d5a91d137e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ANPEP ALS2CL ENPEP	3.56e-05	159	52	4	aaf449c768d6fbb0a1bb47746ff3bdb7f9eb8914
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLA2R1 ANPEP ALS2CL ENPEP	3.56e-05	159	52	4	8bbdef1e927f3130b578d7d7c5ff38bbe06fab63
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GALNS CD163L1 SCIMP FERMT3	3.65e-05	160	52	4	94e4f5fc2156dd8163811c3b8b0781ea9b3f2e06
ToppCell	Smart-seq2-spleen_(Smart-seq2)-hematologic-thrombocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAXDC2 ITGA2B F13A1 FERMT3	3.93e-05	163	52	4	ee3b11e6544d4eac38ca045179ebeace6bede237
ToppCell	Smart-seq2-spleen_(Smart-seq2)-hematologic-thrombocytic-platelet\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAXDC2 ITGA2B F13A1 FERMT3	3.93e-05	163	52	4	c13af6895dc83b8c3bd52b8e1859818fabf85d0e
ToppCell	droplet-Fat-Scat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCIMP DCK F13A1 FERMT3	4.42e-05	168	52	4	749eccebe4ee066f827d2a3980512f195f23ac27
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNPEP DCK F13A1 FERMT3	4.52e-05	169	52	4	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNPEP DCK F13A1 FERMT3	4.52e-05	169	52	4	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	wk_20-22-Hematologic-Meg-ery-Megakaryocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	FAXDC2 ITGA2B F13A1 FERMT3	4.62e-05	170	52	4	eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell	ileum\|World / shred on tissue and cell subclass	ANPEP ERAP2 SI ENPEP	4.62e-05	170	52	4	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	droplet-Heart-HEART-1m-Hematologic-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SCIMP DCK F13A1 FERMT3	5.29e-05	176	52	4	1df640f88667e2dad30e65279d6d33bba75024c1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3-5_THEMIS_ELOF1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PLA2R1 CD163L1 ALS2CL ENPEP	5.29e-05	176	52	4	78306517b1e52411a2ba72f141efea4d12c09f25
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	5.53e-05	178	52	4	a16857da9f2907c176213a326112a1b4cbd0e628
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	ZAN ANPEP SCIMP TGM5	5.65e-05	179	52	4	99894067e2c2a3ed53abdc5434410c3172693496
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAXDC2 ITGA2B F13A1 FERMT3	5.77e-05	180	52	4	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	megakaryocytic-Platelet\|World / Lineage and Cell class	FAXDC2 ITGA2B F13A1 FERMT3	5.77e-05	180	52	4	c007c3e63c2bb35ed34327dd8863899b5db93115
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAXDC2 ITGA2B F13A1 FERMT3	5.77e-05	180	52	4	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|bone_marrow / Manually curated celltypes from each tissue	FAXDC2 ITGA2B F13A1 FERMT3	6.16e-05	183	52	4	3cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	6.29e-05	184	52	4	a5d904dd030d9c21be0f8b9ec432025f90fb5b8e
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANPEP TRPV4 ACSS2 ENPEP	6.29e-05	184	52	4	9434731f651820b05335085582960f08fbf895de
ToppCell	PBMC-Control-Hematopoietic-Platelet-Platelet-plt_3\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	6.29e-05	184	52	4	7617a00b2ebd6c5c9386c39a7e8220fdbf8669ff
ToppCell	megakaryocytic\|World / Lineage and Cell class	FAXDC2 ITGA2B F13A1 FERMT3	6.29e-05	184	52	4	b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAXDC2 ITGA2B F13A1 FERMT3	6.42e-05	185	52	4	0f722ffcc3e78d5c6b1b79d31d00929801a993f1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAXDC2 ITGA2B F13A1 FERMT3	6.42e-05	185	52	4	c985a4b184d382a79aaff07f81c0efede2c2d493
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAXDC2 ITGA2B F13A1 FERMT3	6.42e-05	185	52	4	d0d0e000ebe1fc35a987930ceaf7e3369e0c694c
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	6.42e-05	185	52	4	0a2c8ce92a257d0ec5bcc8efa22792d53752c665
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	FAXDC2 ITGA2B F13A1 FERMT3	6.42e-05	185	52	4	0ca99fcbd30c454bcdc2aa5265a0e4dba25666ea
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells-Platelet\|World / Lineage, cell class and subclass	FAXDC2 ITGA2B F13A1 FERMT3	6.56e-05	186	52	4	27807334e7241c8a9aeaf6403f0fd0b001fbc0d1
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	6.56e-05	186	52	4	4a9b5b3a56229629161d5404db2b8dd76e10cf4b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANPEP TRPV4 ACSS2 ENPEP	6.56e-05	186	52	4	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	Monocytes-M2-like_CD16+_macrophages\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	CD163L1 TRPV4 ALS2CL F13A1	6.69e-05	187	52	4	59e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	ANPEP ELOVL5 ACSS2 ENPEP	6.69e-05	187	52	4	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	LNPEP NPEPPS KDM6A CRY1	6.83e-05	188	52	4	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	6.98e-05	189	52	4	d357fa946b9d6af46c15402f68758fb9c747bcaf
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	6.98e-05	189	52	4	8b4a9434d7b7ca8cf74712227407ed7c96ce02f8
ToppCell	Healthy-Platelet\|World / disease group, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	6.98e-05	189	52	4	c3d8e3682cb489bca887039cbea6c4cfc264de2f
ToppCell	COVID-19_Moderate-Platelet\|COVID-19_Moderate / disease group, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	7.12e-05	190	52	4	3bf4ab3fd3a391da98a83e2aac0881a0e5c8f8b0
ToppCell	COVID-19_Moderate-Platelet\|World / disease group, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	7.12e-05	190	52	4	6e4f4af5ba185bb022753881a26a269a544bb59b
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells\|World / Lineage, cell class and subclass	FAXDC2 ITGA2B F13A1 FERMT3	7.12e-05	190	52	4	72b61a12ccea506272ce9cef9051aa2612e6ce57
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.27e-05	191	52	4	7da172553ed6df4a0c34ecd55665a9598b5071a5
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.27e-05	191	52	4	1a1bf85bc77bf093a0ac2cb9eabaeac820a7b93e
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.27e-05	191	52	4	b9070e62e28e818631e2bbb48e097d1307777a5c
ToppCell	Healthy_donor-Platelet\|World / disease group, cell group and cell class (v2)	FAXDC2 ITGA2B F13A1 FERMT3	7.27e-05	191	52	4	defae87313d6345e3f451250fd66fe8831bb441c
ToppCell	COVID-19_Severe-Platelet\|World / disease group, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	7.27e-05	191	52	4	b8a9fa264ce9fa14ac5e1a6c15025bb6dfe76a11
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_2\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.27e-05	191	52	4	960e0267786794454acbc77ddc766fd5dce99820
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	3b75fe82018bb259b02bfaee96b310f4d6df0350
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	5bf420b03c32d7bbc919616bcb7d69f3e3a459ed
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	f48202c271c9233c78de255a2fa131b219f688d7
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	97975340f9ab3ab6e0aa7751b10e008ff3d21bf2
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	35ae787e90e7e5e333978125e19de1590316c769
ToppCell	PBMC-Severe-Hematopoietic\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	68d0bf6249a24d23cb1b0be434bced2ff2d0f2b4
ToppCell	COVID-19_Severe-Hematopoietic_Mega-Platelet\|COVID-19_Severe / Disease group, lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	6ebdb70cc0292e41b348d38d89f77e9a3b029bd8
ToppCell	COVID-19_Severe-Hematopoietic_Mega\|COVID-19_Severe / Disease group, lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	2764c3c68982077a448ff5da58344e0f6cec0a52
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	3276bd4f1023a020ebb26ec33424b6e9897d31c9
ToppCell	PBMC-Severe-Hematopoietic-Platelet\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.41e-05	192	52	4	9ae14279e9b91e04ea2c5bbbeadb111a1b966bd1
ToppCell	severe_COVID-19-Platelet\|World / disease group, cell group and cell class (v2)	FAXDC2 ITGA2B F13A1 FERMT3	7.56e-05	193	52	4	a598a0665652cc365eb08e413a711c929b80fec7
ToppCell	10x5'-blood\|World / Manually curated celltypes from each tissue	FAXDC2 ITGA2B F13A1 FERMT3	7.56e-05	193	52	4	359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FAXDC2 ITGA2B F13A1 FERMT3	7.56e-05	193	52	4	a2fb7482e79d6ce5b6b1d9d0c0811d1c58b4d85d
ToppCell	COVID-19_Severe-Platelet\|COVID-19_Severe / disease group, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	7.56e-05	193	52	4	d9c2d2f72f9ea01e089f5d769801bcd7de4da617
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_5\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FAXDC2 ITGA2B F13A1 FERMT3	7.56e-05	193	52	4	1d724ccb745cfc624119dd6003d53b84b17c94b0
ToppCell	Megakaryocytic-erythropoietic-Megakaryo-cells-Megakaryocyte\|World / Lineage, cell class and subclass	FAXDC2 ITGA2B F13A1 FERMT3	7.56e-05	193	52	4	352cd442b6e62f09b6d22a139774067873644594
ToppCell	wk_08-11-Hematologic-Myeloid-CX3CR1+_Mac\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD163L1 SCIMP F13A1 FERMT3	7.56e-05	193	52	4	afc20433b5abc9b430751a2aa8d93b0fd136a888
ToppCell	facs-Thymus-nan-3m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR6 NPEPPS DCK F13A1	7.72e-05	194	52	4	f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PLA2R1 ANPEP SI ENPEP	7.72e-05	194	52	4	2f6e62a4ec8707bd5a16c0734c5131af55207ea2
ToppCell	10x5'-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|blood / Manually curated celltypes from each tissue	FAXDC2 ITGA2B F13A1 FERMT3	7.72e-05	194	52	4	63dea7d630962761a70aa88e720ee35c22cbc81a
ToppCell	10x5'-blood-Hematopoietic_Erythro-Mega\|blood / Manually curated celltypes from each tissue	FAXDC2 ITGA2B F13A1 FERMT3	7.72e-05	194	52	4	d0e7d35b5086834929c4bd39d4c6719b2d5fc71e
ToppCell	facs-Thymus-nan-3m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR6 NPEPPS DCK F13A1	7.72e-05	194	52	4	66c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCell	facs-Thymus-nan\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR6 NPEPPS DCK F13A1	7.72e-05	194	52	4	cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCell	severe_COVID-19-Platelet\|severe_COVID-19 / disease group, cell group and cell class (v2)	FAXDC2 ITGA2B F13A1 FERMT3	8.03e-05	196	52	4	2b835fc3db81550555cbbcb3e823d9197ee35662
ToppCell	COVID-19_Severe\|World / disease group, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.03e-05	196	52	4	3bedf60f662b373ad9d0f07d4da9f11864af3a74
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD163L1 SCIMP F13A1 FERMT3	8.19e-05	197	52	4	1c0024049db2d2c817a7f503de235b9630b24e33
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD163L1 SCIMP F13A1 FERMT3	8.19e-05	197	52	4	759f26753f76af3ae8d8527c4d221206245a3d45
ToppCell	3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD163L1 SCIMP F13A1 FERMT3	8.19e-05	197	52	4	09a2c0c0f9c2442743414236c2d5c1f27be66e4c
ToppCell	LPS_anti-TNF\|World / Treatment groups by lineage, cell group, cell type	ANPEP GCGR F13A1 FERMT3	8.19e-05	197	52	4	7768e613fa48a6ec4a3902559310b51345a7fe91
ToppCell	control-Platelet\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.35e-05	198	52	4	fc066f428340478605e7d9ff3c0c645c427c4876
ToppCell	3'-GW_trimst-1-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD163L1 SCIMP F13A1 FERMT3	8.35e-05	198	52	4	be038619157aeaa7a57ebd66392de940df4f8127
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD163L1 SCIMP F13A1 FERMT3	8.35e-05	198	52	4	23314bed02edadccdc5da4fa153142a25e4a440e
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD163L1 SCIMP F13A1 FERMT3	8.35e-05	198	52	4	79c8ab15e73f727c5e110ab9eab3ccb5edf9f714
ToppCell	severe-Platelet\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.51e-05	199	52	4	6539c197c653fce083a893ac422263abbbc07e79
ToppCell	wk_08-11-Hematologic\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD163L1 SCIMP F13A1 FERMT3	8.51e-05	199	52	4	edc9afd7be8543cb93a2bb874a14aad0417dfa92
ToppCell	wk_08-11-Hematologic-Myeloid-SPP1+_Mac\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD163L1 SCIMP F13A1 FERMT3	8.51e-05	199	52	4	d94cf750599366061066074e8007d707adf6fc5a
ToppCell	severe-Platelet\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.51e-05	199	52	4	abda45c709469181d8224ae66216ed18ec370fd2
ToppCell	MS-IIF-Others-Platelet\|IIF / Disease, condition lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.68e-05	200	52	4	2254319216f1c2e0a0f015ea530c1e6a55a92d5d
ToppCell	Control-Control-Myeloid-Neutrophil\|Control / Disease, condition lineage and cell class	PLA2R1 ANPEP USP32 MTMR3	8.68e-05	200	52	4	95c41f147a1594d49e73cb56d86d301c3115ce20
ToppCell	Control-Control-Others-Platelet\|Control / Disease, condition lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.68e-05	200	52	4	e0463c93714ab5fd00f294cca83bd61027fe0e95
ToppCell	COVID-19-COVID-19_Severe-Others-Platelet\|COVID-19_Severe / Disease, condition lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.68e-05	200	52	4	af373636f540544addd94f51ce94ea2cb1f3ecc9
ToppCell	wk_08-11-Hematologic-Myeloid\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CD163L1 SCIMP F13A1 FERMT3	8.68e-05	200	52	4	148e09e27e4a563bdd1fbe9a593cd938885cbb1b
ToppCell	COVID-19-COVID-19_Severe-Others\|COVID-19_Severe / Disease, condition lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.68e-05	200	52	4	932b310a2838e4b354b90460fa904a8ebca4747a
ToppCell	MS-Multiple_Sclerosis-Others-Platelet\|Multiple_Sclerosis / Disease, condition lineage and cell class	FAXDC2 ITGA2B F13A1 FERMT3	8.68e-05	200	52	4	263d956136747c209951b4358f2e1672a21d8eef
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Abcc9_(Mural.Rgs5Acta2.Abcc9)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PLA2R1 ANPEP ENPEP	2.31e-04	102	52	3	72ce247dad7404e6b9c971b5c29d3c6846da5efc
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2-MURAL_Mural.Rgs5Acta2.Abcc9_(Mural.Rgs5Acta2.Abcc9)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PLA2R1 ANPEP ENPEP	2.31e-04	102	52	3	8c4d9483ff983538593f4e17f4a74a93cdda59c4
ToppCell	Frontal_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	PLA2R1 ANPEP ENPEP	2.31e-04	102	52	3	5feedce6d26a578c4aaba4e4824b3d0c3f3806bc
ToppCell	Striatum-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TGM1 TRPV4 F13A1	3.54e-04	118	52	3	97db1193ecc885f63840663ab969468ce21cba74
Drug	5-(biotinamido)pentylamine	TGM1 TGM3 TGM6 F13A1 TGM5	8.20e-11	14	50	5	CID000083906
Drug	monodansylthiacadaverine	TGM1 TGM3 TGM6 F13A1 TGM5	2.52e-10	17	50	5	CID000162694
Drug	Fumadil B	ANPEP RNPEP ERAP2 ERAP1 LNPEP ENPEP	1.96e-09	54	50	6	CID000003430
Drug	l 3000	ANPEP RNPEP LNPEP NPEPPS ENPEP	3.24e-09	27	50	5	CID000102475
Drug	trifluralin	ANPEP RNPEP ERAP2 ERAP1 LNPEP ITGA2B ENPEP	1.44e-08	131	50	7	CID000005569
Drug	cystamine	FBXO16 TGM1 TGM3 GALNS TGM6 F13A1 TGM5	1.34e-07	181	50	7	CID000002915
Drug	AP-A	ANPEP RNPEP LNPEP ENPEP	2.12e-07	24	50	4	CID000188964
Drug	TG-2	TGM1 TGM3 TGM6 F13A1 TGM5	2.66e-07	63	50	5	CID000574319
Drug	(2R)-2-[(R)-carboxy-[[(2Z)-2-(2-furyl)-2-methoxyimino-acetyl]amino]methyl]-5-methylene-2H-1,3-thiazine-4-carboxylic acid	TGM1 TGM3 TGM6 F13A1 TGM5	2.88e-07	64	50	5	CID011987767
Drug	glycine ethyl ester	TGM1 GALNS ENPEP F13A1	2.97e-07	26	50	4	CID000012175
Drug	AC1L22WP	TGM1 TGM3 TGM6 F13A1 TGM5	3.36e-07	66	50	5	CID000065254
Drug	cadaverine	TGM1 TGM3 TGM6 F13A1 TGM5	4.52e-07	70	50	5	CID000000273
Drug	didansylcadaverine	TGM1 TGM6 TGM5	5.54e-07	8	50	3	CID000108731
Drug	aminopeptidase N inhibitor	ANPEP RNPEP ENPEP	5.54e-07	8	50	3	CID010067728
Drug	methionine	ANPEP RNPEP ERAP2 ERAP1 LNPEP ENPEP	7.28e-07	144	50	6	CID000000876
Drug	AC1L1A6N	ANPEP RNPEP ENPEP	8.29e-07	9	50	3	CID000000858
Drug	1-(5-aminopentyl)-3-phenylthiourea	TGM1 TGM6 TGM5	1.62e-06	11	50	3	CID003035524
Drug	Tg 5	TGM1 TGM6 TGM5	2.16e-06	12	50	3	CID000205491
Drug	dansyl chloride	TGM1 TGM3 TGM6 F13A1 TGM5	3.91e-06	108	50	5	CID000011801
Drug	AC1L2DAI	ANPEP RNPEP ERAP2 ERAP1 LNPEP NPEPPS ENPEP	4.31e-06	304	50	7	CID000004984
Drug	2-naphthylalanine amide	ANPEP RNPEP ENPEP	4.45e-06	15	50	3	CID000098159
Drug	monodansylcadaverine	TGM1 TGM3 TGM6 F13A1 TGM5	4.47e-06	111	50	5	CID000004247
Drug	Matlystatin A	ANPEP RNPEP	4.73e-06	2	50	2	CID000132294
Drug	Austricine [10180-88-8]; Down 200; 14.2uM; MCF7; HT_HG-U133A	ERAP1 FBXO42 MTMR3 PTDSS2 SFI1 KDM6A	4.91e-06	200	50	6	4797_DN
Drug	Arg-beta-naphthylamide	ANPEP RNPEP LNPEP	5.47e-06	16	50	3	CID000151452
Drug	pentylamine	TGM1 TGM6 F13A1 TGM5	5.57e-06	53	50	4	CID000008060
Drug	AC1MPJID	TGM1 TGM3 TGM6 F13A1 TGM5	5.79e-06	117	50	5	CID003386230
Drug	NSC265489	LVRN ANPEP RNPEP LNPEP ENPEP	8.64e-06	127	50	5	CID000003238
Drug	NSC 118380	ANPEP NPEPPS ENPEP	1.11e-05	20	50	3	CID000070910
Drug	NSC90351	ANPEP SI	1.42e-05	3	50	2	CID000259791
Drug	L-leucine-p-nitroanilide	ANPEP LNPEP ENPEP	1.49e-05	22	50	3	CID000121895
Drug	p-nitroaniline	CRNKL1 ANPEP RNPEP LNPEP	1.70e-05	70	50	4	CID000007475
Drug	l-Alanyl-l-glutamine	TGM1 ANPEP TGM6 F13A1 TGM5	1.94e-05	150	50	5	CID000123935
Drug	putrescine	TGM1 TGM3 TGM6 F13A1 TGM5	2.13e-05	153	50	5	CID000001045
Drug	Pro-leu	ANPEP RNPEP NPEPPS	3.50e-05	29	50	3	CID000173815
Drug	pirimiphos methyl	ZAN ANPEP RNPEP ELOVL5 GCGR	4.40e-05	178	50	5	ctd:C014153
Drug	lysyl-p-nitroanilide	ANPEP NPEPPS	4.71e-05	5	50	2	CID000151405
Drug	iodoacetamide	TGM1 TGM3 TGM6 F13A1 TGM5	4.76e-05	181	50	5	CID000003727
Drug	TG-3	TGM1 TGM6 TGM5	5.19e-05	33	50	3	CID000205489
Drug	Leu-Gly-Pro	ANPEP NPEPPS	7.05e-05	6	50	2	CID000439585
Drug	EC27	ANPEP ENPEP	7.05e-05	6	50	2	CID000168100
Drug	diisopropylfluorophosphate	ANPEP RNPEP ERAP2 ERAP1 LNPEP ENPEP	7.07e-05	321	50	6	CID000005936
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	LNPEP MTMR3 FAXDC2 SFI1 KDM6A	7.12e-05	197	50	5	1003_UP
Drug	Raloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; PC3; HT_HG-U133A	TGM3 TRPC4 MTMR3 AQP4 F13A1	7.12e-05	197	50	5	5759_UP
Drug	CP-863187 [668981-07-5]; Down 200; 10uM; MCF7; HT_HG-U133A	ELOVL5 PTDSS2 ITGA2B ALS2CL KDM6A	7.12e-05	197	50	5	7553_DN
Drug	Lobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; PC3; HT_HG-U133A	GCGR ITGA2B AQP4 ENPEP TGM5	7.29e-05	198	50	5	5080_UP
Drug	Ritodrine hydrochloride [23239-51-2]; Up 200; 12.4uM; MCF7; HT_HG-U133A	MTMR3 FAXDC2 SFI1 AQP4 ENPEP	7.47e-05	199	50	5	2635_UP
Drug	DB07202	GALNS ANPEP ENPEP	7.96e-05	38	50	3	CID011221386
Drug	aspartyl-phenylalanine	NPFFR2 ANPEP RNPEP ENPEP	9.32e-05	108	50	4	CID000541493
Drug	m-fluorophenylalanine	ANPEP RNPEP	9.86e-05	7	50	2	CID000009976
Drug	S-benzyl-L-cysteine-p-nitroanilide	ANPEP LNPEP	9.86e-05	7	50	2	CID000081941
Drug	mergetpa	ANPEP RNPEP ENPEP	1.00e-04	41	50	3	CID000123726
Drug	Epiamastatin hydrochloride	ANPEP RNPEP LNPEP ENPEP	1.19e-04	115	50	4	CID000003237
Drug	n-propylacrylamide	TGM1 ANPEP	1.31e-04	8	50	2	CID000114794
Drug	phenylisothiocyanate	ANPEP RNPEP F13A1	1.42e-04	46	50	3	CID000007673
Drug	taurine-ursodeoxycholate conjugate	ELOVL5 ACSS2 AQP4	1.42e-04	46	50	3	ctd:C030141
Drug	L024104	ANPEP RNPEP SI	1.61e-04	48	50	3	CID003025353
Drug	DGM-2	TGM1 F13A1	1.68e-04	9	50	2	CID000016891
Drug	AC1NRAX5	TGM1 F13A1	1.68e-04	9	50	2	CID005288137
Drug	Hypertensin	RNPEP LNPEP	1.68e-04	9	50	2	CID000005890
Drug	NSC-694280	ANPEP RNPEP NPEPPS ENPEP	1.74e-04	127	50	4	CID000004802
Drug	glutamate thiol	ANPEP ENPEP	2.10e-04	10	50	2	CID000125415
Drug	AC1Q5JYX	ANPEP RNPEP ENPEP	2.28e-04	54	50	3	CID000002020
Drug	spermidine	TGM1 TGM3 TGM6 F13A1 TGM5	2.29e-04	253	50	5	CID000001102
Drug	NSC55260	GALNS ANPEP	2.57e-04	11	50	2	CID005356351
Drug	forphenicine	RNPEP ENPEP	2.57e-04	11	50	2	CID000042560
Drug	lysylphenylalanine	ANPEP NPEPPS	2.57e-04	11	50	2	CID000151410
Drug	1,10-phenanthroline	ANPEP RNPEP LNPEP NPEPPS ENPEP	2.94e-04	267	50	5	CID000001318
Drug	alanine	FBXO16 TGM1 GALNS ANPEP RNPEP	3.04e-04	269	50	5	CID000000602
Drug	3-fluorotyrosine	ANPEP SI	3.08e-04	12	50	2	CID000092100
Drug	mercuric oxide	GALNS SI	3.08e-04	12	50	2	CID000030856
Drug	CdTe	TGM1 CRNKL1	3.08e-04	12	50	2	CID000091501
Drug	YS980	ANPEP ENPEP	3.63e-04	13	50	2	CID000171857
Drug	esterastin	RNPEP ENPEP	3.63e-04	13	50	2	CID000125669
Disease	endoplasmic reticulum aminopeptidase 1 measurement	ERAP2 ERAP1 LNPEP	1.80e-07	7	52	3	EFO_0008119
Disease	severe pre-eclampsia (is_marker_for)	ERAP2 ERAP1 LNPEP	2.87e-07	8	52	3	DOID:13129 (is_marker_for)
Disease	endoplasmic reticulum aminopeptidase 2 measurement	ERAP2 LNPEP	3.05e-06	2	52	2	EFO_0801566
Disease	cognitive inhibition measurement	TGM3 TGM6 TGM5	9.54e-05	50	52	3	EFO_0007969
Disease	ankylosing spondylitis	ERAP2 ERAP1 NPEPPS	5.62e-04	91	52	3	EFO_0003898
Disease	urate measurement, body mass index	ERAP2 ERAP1	1.28e-03	30	52	2	EFO_0004340, EFO_0004531
Disease	Ataxia, Spinocerebellar	ELOVL5 TGM6	1.65e-03	34	52	2	C0087012
Disease	Spinocerebellar Ataxia Type 2	ELOVL5 TGM6	1.65e-03	34	52	2	C0752121
Disease	Spinocerebellar Ataxia Type 1	ELOVL5 TGM6	1.65e-03	34	52	2	C0752120
Disease	Spinocerebellar Ataxia Type 5	ELOVL5 TGM6	1.65e-03	34	52	2	C0752123
Disease	Spinocerebellar Ataxia Type 7	ELOVL5 TGM6	1.65e-03	34	52	2	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	ELOVL5 TGM6	1.65e-03	34	52	2	C0752124
Disease	Spinocerebellar Ataxia Type 4	ELOVL5 TGM6	1.75e-03	35	52	2	C0752122

Protein segments in the cluster

Peptide	Gene	Start	Entry
SQGQAVWQWKVTWAV	ALS2CL	301	Q60I27
AVIMGNWENHWIYWV	AQP4	221	P55087
QKAWNWWNLNIHVHA	ERICH6B	566	Q5W0A0
WFGNLVTNANWGEFW	RNPEP	331	Q9H4A4
MRDNEKAWWQQWTSH	CATSPER4	1	Q7RTX7
NVNNWHWTERDASNW	AHSA1	21	O95433
AHQWFGNLVTIEWWN	ANPEP	391	P15144
DVQISWNQGIDLWWH	ACSS2	276	Q9NR19
WNQGIDLWWHELMQE	ACSS2	281	Q9NR19
WFGNLVTMNWWNNIW	LVRN	421	Q6Q4G3
VTMNWWNNIWLNEGF	LVRN	426	Q6Q4G3
IHEQWWTICDQNWKN	CD163L1	386	Q9NR16
KWDTNSSENWHPIWN	NPFFR2	106	Q9Y5X5
MSNDVWVLDLEQWAW	FBXO42	256	Q6P3S6
WMSSFWGHSWREEDQ	LNP1	16	A1A4G5
HHASMLNIWWFVMNW	ELOVL5	146	Q9NYP7
LNIWWFVMNWVPCGH	ELOVL5	151	Q9NYP7
HWVQAIGWCNNIAWN	KDM6A	1226	O15550
AHQWFGNLVTMEWWN	ERAP1	356	Q9NZ08
GNLVTMEWWNDLWLN	ERAP1	361	Q9NZ08
NVQCWTSNDNMGFWW	GCGR	291	P47871
LWENQGAGWWHNVSA	MEGF8	206	Q7Z7M0
GSWAFMWQQVFEPTW	METTL7B	181	Q6UX53
WNYHCWNEAWMTRPD	F13A1	371	P00488
LAHQWFGNLVTMKWW	LNPEP	466	Q9UIQ6
VHQWFGNIVTMDWWE	ENPEP	396	Q07075
GNIVTMDWWEDLWLN	ENPEP	401	Q07075
VDEFWWFPHMWSHMQ	NDST4	371	Q9H3R1
HQWFGNLVTMEWWTH	NPEPPSL1	356	A6NEC2
HFWTWTNSWENFRQG	GALNS	401	P34059
FWNSVTWHLQRFWGA	FAXDC2	41	Q96IV6
WMEWQPEEQAWHSYI	CRNKL1	336	Q9BZJ0
LHLWDQWFRGWAEQE	C14orf119	96	Q9NWQ9
LDADWSINAGSWMWL	CRY1	386	Q16526
WFGNLVTMEWWNDIW	ERAP2	376	Q6P179
EWTIYQDWHDWMNNQ	DCK	151	P27707
CWHWKNLAELDQLWM	FBXO16	116	Q8IX29
DWCWMAQWVTTNGYD	PRSS51	121	A0A1B0GVH4
HQWFGNLVTMEWWTH	NPEPPS	356	P55786
NLVTMEWWTHLWLNE	NPEPPS	361	P55786
SWWGWRNADDEHLVQ	MTMR3	241	Q13615
EFHMAQLLRWAWSQW	SFI1	611	A8K8P3
VQDSTAMSWWRNNFW	SCIMP	6	Q6UWF3
PNFSECWWDHWIMDV	PTDSS2	236	Q9BVG9
WLGDNTASWEQMEWS	SI	601	P14410
DWTQKWNDWQALMEH	STARD9	446	Q9P2P6
WSDVIVACAPWQHWN	ITGA2B	131	P08514
WMGLNQLDEHAGWQW	PLA2R1	291	Q13018
SVWNFHVWNEGWFVR	TGM3	326	Q08188
WGVFRNEDQWAWVLQ	SPPL2B	311	Q8TCT7
TWRFSNMRQWNVNWD	FERMT3	591	Q86UX7
DTIWNFHVWNECWMA	TGM5	331	O43548
QGHFWELWRSGLWNM	WDR6	101	Q9NNW5
WMQTNNSSHWTEFLW	ZBED9	486	Q6R2W3
SVWNFHVWNDCWMKR	TGM1	431	P22735
MYWQNWTHNGRLWGA	nan	1	Q6AWC8
WCFRVDEVNWSHWNQ	TRPV4	776	Q9HBA0
EDSMWNFHVWNESWF	TGM6	326	O95932
QAGHNWFIISMQWWQ	USP32	391	Q8NFA0
MWDGGLQDYIHDWWN	TRPC4	421	Q9UBN4
WHHNNPVGTEWLWKM	TYW1B	361	Q6NUM6
DVLWKHWNTQRPSWM	ZAN	146	Q9Y493