Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionlinoleoyl-CoA desaturase activity

FADS1 FADS2

4.34e-0521322GO:0016213
GeneOntologyMolecularFunctionendopolyphosphatase activity

NUDT4B NUDT4

4.28e-0451322GO:0000298
GeneOntologyMolecularFunctionacyl-CoA desaturase activity

FADS1 FADS2

4.28e-0451322GO:0016215
GeneOntologyMolecularFunctionbis(5'-adenosyl)-hexaphosphatase activity

NUDT4B NUDT4

4.28e-0451322GO:0034431
GeneOntologyMolecularFunctiondiphosphoinositol-polyphosphate diphosphatase activity

NUDT4B NUDT4

4.28e-0451322GO:0008486
GeneOntologyMolecularFunctionpyrophosphatase activity

ENTPD7 ATP7A RNF213 CHD1 RAD54L2 NUDT4B HELQ ENTPD4 MFN1 NUDT4 MACF1 GNAT2 SNRNP200 RAD54L DNAH11

4.39e-0483913215GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

ENTPD7 ATP7A RNF213 CHD1 RAD54L2 NUDT4B HELQ ENTPD4 MFN1 NUDT4 MACF1 GNAT2 SNRNP200 RAD54L DNAH11

4.45e-0484013215GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

ENTPD7 ATP7A RNF213 CHD1 RAD54L2 NUDT4B HELQ ENTPD4 MFN1 NUDT4 MACF1 GNAT2 SNRNP200 RAD54L DNAH11

4.45e-0484013215GO:0016818
GeneOntologyMolecularFunctionbis(5'-adenosyl)-pentaphosphatase activity

NUDT4B NUDT4

6.39e-0461322GO:0034432
GeneOntologyMolecularFunctionCTPase activity

ENTPD7 ENTPD4

6.39e-0461322GO:0043273
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate binding

SESTD1 HIP1R SNX5

1.11e-03311323GO:0080025
GeneOntologyCellularComponentt-UTP complex

NOL11 HEATR1

1.22e-0431342GO:0034455
DomainCYTOCHROME_B5_2

FADS1 FADS2 HERC2

8.75e-05131293PS50255
DomainCYTOCHROME_B5_1

FADS1 FADS2 HERC2

8.75e-05131293PS00191
DomainCyt-b5

FADS1 FADS2 HERC2

1.11e-04141293PF00173
Domain-

FADS1 FADS2 HERC2

1.11e-041412933.10.120.10
DomainCyt_B5-like_heme/steroid-bd

FADS1 FADS2 HERC2

1.11e-04141293IPR001199
DomainCyt-b5

FADS1 FADS2 HERC2

1.11e-04141293SM01117
DomainFatty_acid_desaturase

FADS1 FADS2

1.41e-0431292IPR012171
DomainRetinoicA-induced_16-like

FHIP2A FHIP2B

2.81e-0441292IPR019384
DomainRAI16-like

FHIP2A FHIP2B

2.81e-0441292PF10257
DomainGroucho_enhance

TLE2 TLE4

4.67e-0451292IPR009146
DomainTLE_N

TLE2 TLE4

4.67e-0451292PF03920
DomainGroucho/TLE_N

TLE2 TLE4

4.67e-0451292IPR005617
DomainHelicase_C

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

8.81e-041071295PF00271
DomainHELICc

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

8.81e-041071295SM00490
DomainHelicase_C

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

9.18e-041081295IPR001650
DomainHELICASE_CTER

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

9.57e-041091295PS51194
DomainHELICASE_ATP_BIND_1

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

9.57e-041091295PS51192
DomainDEXDc

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

9.57e-041091295SM00487
DomainHelicase_ATP-bd

CHD1 RAD54L2 HELQ SNRNP200 RAD54L

9.97e-041101295IPR014001
DomainFA_desaturase_dom

FADS1 FADS2

1.29e-0381292IPR005804
DomainFA_desaturase

FADS1 FADS2

1.29e-0381292PF00487
DomainGDA1_CD39_NTPase

ENTPD7 ENTPD4

1.29e-0381292IPR000407
DomainGDA1_CD39

ENTPD7 ENTPD4

1.29e-0381292PF01150
DomainGDA1_CD39_NTPASE

ENTPD7 ENTPD4

1.29e-0381292PS01238
DomainSNF2_N

CHD1 RAD54L2 RAD54L

1.38e-03321293IPR000330
DomainSNF2_N

CHD1 RAD54L2 RAD54L

1.38e-03321293PF00176
DomainSPEC

SESTD1 TRIO MACF1

1.38e-03321293SM00150
DomainSpectrin/alpha-actinin

SESTD1 TRIO MACF1

1.38e-03321293IPR018159
Domain-

RNF213 CHD1 PFKFB1 RAD54L2 HELQ NLRP2 DNAH14 MFN1 NWD2 GNAT2 SNRNP200 RAD54L DNAH11

1.97e-03746129133.40.50.300
DomainP-loop_NTPase

RNF213 CHD1 PFKFB1 RAD54L2 HELQ NLRP2 DNAH14 MFN1 NWD2 STARD9 GNAT2 SNRNP200 RAD54L DNAH11

2.19e-0384812914IPR027417
Domain-

RGPD2 CCNF IFIT1B IFT122 CFAP70 ANAPC5

3.17e-0320712961.25.40.10
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH11

4.08e-03141292IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH11

4.08e-03141292IPR024743
DomainMT

DNAH14 DNAH11

4.08e-03141292PF12777
DomainAAA_8

DNAH14 DNAH11

4.08e-03141292PF12780
DomainGalactose-bd-like

CEP104 ALLC LAMB2 HERC2

4.10e-03941294IPR008979
Domain-

CEP104 RTTN RICTOR FRYL HEATR1 PPP4R4

4.46e-0322212961.25.10.10
DomainDHC_fam

DNAH14 DNAH11

4.69e-03151292IPR026983
DomainDynein_heavy

DNAH14 DNAH11

4.69e-03151292PF03028
DomainDynein_heavy_dom

DNAH14 DNAH11

4.69e-03151292IPR004273
DomainTPR-like_helical_dom

RGPD2 CCNF IFIT1B IFT122 CFAP70 ANAPC5

5.63e-032331296IPR011990
DomainCyclin_C-dom

CCNF CCNA1

6.02e-03171292IPR004367
DomainCyclin_C

CCNF CCNA1

6.02e-03171292PF02984
DomainCyclin_C

CCNF CCNA1

6.02e-03171292SM01332
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SESTD1 RASA2 EPB41L4B NOL11 RICTOR FRYL HEATR1 BCOR PLA2G15 DIS3 MTPN TEX264 TLE4 MACF1 POGLUT2 POLK VPS13B FHIP2B SNX5

3.90e-0810841341911544199
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ENTPD7 LAMB2 RNF213 LANCL1 PLXND1 LMBRD2 PLA2G15 ERLEC1 MTPN GSTM3 GORASP2 NUDT4 FANCI FADS2 CNPY3 NCEH1 POGLUT2 SNX5

8.98e-0712011341835696571
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CENPF NOL11 CHD1 FRYL HEATR1 ADNP DIS3 GFPT1 FANCI GEMIN4 MACF1 HERC2 SNRNP200

1.59e-066531341322586326
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

VIL1 EAF2 NEB APEX2 FANCI MACF1 DNAH11

2.19e-06152134734299191
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

CENPF VPS50 HEATR1 DIS3 GFPT1 GSTM3 RBSN SACS GEMIN4 SNU13 MACF1

3.93e-064981341136634849
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SLC37A1 RASA2 TRIO EPB41L4B STAP2 RNF213 SLITRK3 FRYL PFKFB1 COG3 INTS3 DNAH14 PPP4R4 MALT1 MACF1 DCLK2 IFT122 POLK VPS13B

4.61e-0614891341928611215
Pubmed

Genome-wide association study identifies three susceptibility loci for laryngeal squamous cell carcinoma in the Chinese population.

GRIN2A FADS1 FADS2

4.62e-069134325194280
Pubmed

Targeting RICTOR Sensitizes SMAD4-Negative Colon Cancer to Irinotecan.

HIP1R LAMB2 RICTOR NLRP2 TUBGCP6 MALT1 SNX5

7.44e-06183134731932471
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

TRIO CENPF FRYL APEX2 MACF1 HERC2

7.45e-06120134631413325
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

DENND4A TRIO CENPF NOL11 LANCL1 CHD1 HEATR1 ADNP PLA2G15 DIS3 GFPT1 SPDL1 NUDT4 FANCI STARD9 GEMIN4 SNU13 SNRNP200

9.65e-0614251341830948266
Pubmed

Defining the membrane proteome of NK cells.

SLC37A1 ATP7A VPS50 RNF213 HEATR1 LMBRD2 DIS3 TUBGCP6 FADS1 EIF4ENIF1 FANCI GEMIN4 FADS2 NCEH1 IFT122 HERC2

1.17e-0511681341619946888
Pubmed

Impact of FADS genotype on polyunsaturated fatty acid content in human milk extracellular vesicles: A genetic association study.

FADS1 FADS2

1.47e-052134238566550
Pubmed

Dietary n-3 and n-6 polyunsaturated fatty acids, the FADS gene, and the risk of gastric cancer in a Korean population.

FADS1 FADS2

1.47e-052134229491470
Pubmed

FADS1 FADS2 gene cluster, PUFA intake and blood lipids in children: results from the GINIplus and LISAplus studies.

FADS1 FADS2

1.47e-052134222629455
Pubmed

Variants of the FADS1 FADS2 gene cluster, blood levels of polyunsaturated fatty acids and eczema in children within the first 2 years of life.

FADS1 FADS2

1.47e-052134220948998
Pubmed

Association of FADS1/2 Locus Variants and Polyunsaturated Fatty Acids With Aortic Stenosis.

FADS1 FADS2

1.47e-052134232186652
Pubmed

Dietary oils and FADS1-FADS2 genetic variants modulate [13C]α-linolenic acid metabolism and plasma fatty acid composition.

FADS1 FADS2

1.47e-052134223221573
Pubmed

FADS gene variants modulate the effect of dietary fatty acid intake on allergic diseases in children.

FADS1 FADS2

1.47e-052134221793953
Pubmed

Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.

FADS1 FADS2

1.47e-052134223160180
Pubmed

Decreased liver fatty acid delta-6 and delta-5 desaturase activity in obese patients.

FADS1 FADS2

1.47e-052134219875987
Pubmed

Genetic variants of the fatty acid desaturase gene cluster predict amounts of red blood cell docosahexaenoic and other polyunsaturated fatty acids in pregnant women: findings from the Avon Longitudinal Study of Parents and Children.

FADS1 FADS2

1.47e-052134221106917
Pubmed

FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer.

FADS1 FADS2

1.47e-052134238926633
Pubmed

Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.

RC3H1 MALT1

1.47e-052134237988467
Pubmed

FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases.

FADS1 FADS2

1.47e-052134219776639
Pubmed

FADS1-FADS2 gene cluster confers risk to polycystic ovary syndrome.

FADS1 FADS2

1.47e-052134226879377
Pubmed

Delta-5 and delta-6 desaturases: crucial enzymes in polyunsaturated fatty acid-related pathways with pleiotropic influences in health and disease.

FADS1 FADS2

1.47e-052134225038994
Pubmed

Compensatory induction of Fads1 gene expression in heterozygous Fads2-null mice and by diet with a high n-6/n-3 PUFA ratio.

FADS1 FADS2

1.47e-052134227613800
Pubmed

GWAS-identified bipolar disorder risk allele in the FADS1/2 gene region links mood episodes and unsaturated fatty acid metabolism in mutant mice.

FADS1 FADS2

1.47e-052134236806390
Pubmed

Common genetic variants of the FADS1 FADS2 gene cluster and their reconstructed haplotypes are associated with the fatty acid composition in phospholipids.

FADS1 FADS2

1.47e-052134216670158
Pubmed

Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease.

FADS1 FADS2

1.47e-052134227004414
Pubmed

Dietary pattern regulates fatty acid desaturase 1 gene expression in Indian pregnant women to spare overall long chain polyunsaturated fatty acids levels.

FADS1 FADS2

1.47e-052134230511301
Pubmed

Do FADS genotypes enhance our knowledge about fatty acid related phenotypes?

FADS1 FADS2

1.47e-052134219948371
Pubmed

The role of fatty acid desaturase (FADS) genes in oleic acid metabolism: FADS1 Δ7 desaturates 11-20:1 to 7,11-20:2.

FADS1 FADS2

1.47e-052134229413358
Pubmed

Insertion-deletions in a FADS2 intron 1 conserved regulatory locus control expression of fatty acid desaturases 1 and 2 and modulate response to simvastatin.

FADS1 FADS2

1.47e-052134222748975
Pubmed

Genetic variation in FADS genes is associated with maternal long-chain PUFA status but not with cognitive development of infants in a high fish-eating observational study.

FADS1 FADS2

1.47e-052134226474818
Pubmed

Differences in arachidonic acid levels and fatty acid desaturase (FADS) gene variants in African Americans and European Americans with diabetes or the metabolic syndrome.

FADS1 FADS2

1.47e-052134221733300
Pubmed

Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 ( FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes.

FADS1 FADS2

1.47e-052134218479586
Pubmed

Differences in erythrocyte phospholipid membrane long-chain polyunsaturated fatty acids and the prevalence of fatty acid desaturase genotype among African Americans and European Americans.

FADS1 FADS2

1.47e-052134233310680
Pubmed

Genetic variants of the FADS1 FADS2 gene cluster are associated with altered (n-6) and (n-3) essential fatty acids in plasma and erythrocyte phospholipids in women during pregnancy and in breast milk during lactation.

FADS1 FADS2

1.47e-052134218936223
Pubmed

Genome-wide analysis identifies genetic effects on reproductive success and ongoing natural selection at the FADS locus.

FADS1 FADS2

1.47e-052134236864135
Pubmed

FADS1 FADS2 gene variants modify the association between fish intake and the docosahexaenoic acid proportions in human milk.

FADS1 FADS2

1.47e-052134220335541
Pubmed

Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism.

FADS1 FADS2

1.47e-052134220045144
Pubmed

FADS genotypes and desaturase activity estimated by the ratio of arachidonic acid to linoleic acid are associated with inflammation and coronary artery disease.

FADS1 FADS2

1.47e-052134218842780
Pubmed

Associations between Fatty Acid Intake and Status, Desaturase Activities, and FADS Gene Polymorphism in Centrally Obese Postmenopausal Polish Women.

FADS1 FADS2

1.47e-052134230103441
Pubmed

SNPs of the FADS gene cluster are associated with polyunsaturated fatty acids in a cohort of patients with cardiovascular disease.

FADS1 FADS2

1.47e-052134218320251
Pubmed

FAM160B1 deficit associated with microcephaly, severe intellectual disability, ataxia, behavioral abnormalities and speech problems.

FHIP2A FHIP2B

1.47e-052134231353455
Pubmed

A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle.

FADS1 FADS2

1.47e-052134220364269
Pubmed

Relationship between a common variant in the fatty acid desaturase (FADS) cluster and eicosanoid generation in humans.

FADS1 FADS2

1.47e-052134224962583
Pubmed

Long-chain polyunsaturated fatty acid status in obesity: a systematic review and meta-analysis.

FADS1 FADS2

1.47e-052134225828602
Pubmed

FADS2 polymorphisms are associated with plasma arachidonic acid and estimated desaturase-5 activity in a cross-sectional study.

FADS1 FADS2

1.47e-052134233011673
Pubmed

Dietary n-3 and n-6 polyunsaturated fatty acid intake interacts with FADS1 genetic variation to affect total and HDL-cholesterol concentrations in the Doetinchem Cohort Study.

FADS1 FADS2

1.47e-052134220484448
Pubmed

Adiposity Associated Plasma Linoleic Acid is Related to Demographic, Metabolic Health and Haplotypes of FADS1/2 Genes in Irish Adults.

FADS1 FADS2

1.47e-052134229388724
Pubmed

Docosahexaenoic acid (DHA) supplementation in pregnancy differentially modulates arachidonic acid and DHA status across FADS genotypes in pregnancy.

FADS1 FADS2

1.47e-052134225500337
Pubmed

FADS Gene Polymorphisms, Fatty Acid Desaturase Activities, and HDL-C in Type 2 Diabetes.

FADS1 FADS2

1.47e-052134228555039
Pubmed

Influence of FADS polymorphisms on tracking of serum glycerophospholipid fatty acid concentrations and percentage composition in children.

FADS1 FADS2

1.47e-052134221818279
Pubmed

Associations of umbilical cord fatty acid profiles and desaturase enzyme indices with birth weight for gestational age in Japanese infants.

FADS1 FADS2

1.47e-052134233387849
Pubmed

The role of FADS1/2 polymorphisms on cardiometabolic markers and fatty acid profiles in young adults consuming fish oil supplements.

FADS1 FADS2

1.47e-052134224936800
Pubmed

Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements.

FADS1 FADS2

1.47e-052134218626191
Pubmed

The AGC kinase SGK1 regulates TH1 and TH2 differentiation downstream of the mTORC2 complex.

SGK1 RICTOR

1.47e-052134224705297
Pubmed

High Frequency of Ancestral Haplotype A of Fatty Acid Desaturase Genes in the Yakut Population.

FADS1 FADS2

1.47e-052134238860387
Pubmed

Brain tissue- and cell type-specific eQTL Mendelian randomization reveals efficacy of FADS1 and FADS2 on cognitive function.

FADS1 FADS2

1.47e-052134238316767
Pubmed

FADS1-FADS2 genetic polymorphisms are associated with fatty acid metabolism through changes in DNA methylation and gene expression.

FADS1 FADS2

1.47e-052134230157936
Pubmed

A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids.

FADS1 FADS2

1.47e-052134222619218
Pubmed

Limited Evidence for Selection at the FADS Locus in Native American Populations.

FADS1 FADS2

1.47e-052134232145021
Pubmed

FADS Polymorphism, Omega-3 Fatty Acids and Diabetes Risk: A Systematic Review.

FADS1 FADS2

1.47e-052134229899246
Pubmed

Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism.

FADS1 FADS2

1.47e-052134219809313
Pubmed

Maternal polymorphisms in the FADS1 and FADS2 genes modify the association between PUFA ingestion and plasma concentrations of omega-3 polyunsaturated fatty acids.

FADS1 FADS2

1.47e-052134231568926
Pubmed

Genetic variation of the FADS1 FADS2 gene cluster and n-6 PUFA composition in erythrocyte membranes in the European Prospective Investigation into Cancer and Nutrition-Potsdam study.

FADS1 FADS2

1.47e-052134220691134
Pubmed

Erythrocyte membrane phospholipid fatty acids, desaturase activity, and dietary fatty acids in relation to risk of type 2 diabetes in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study.

FADS1 FADS2

1.47e-052134220980488
Pubmed

Increasing dietary EPA and DHA influence estimated fatty acid desaturase activity in systemic organs which is reflected in the red blood cell in mice.

FADS1 FADS2

1.47e-052134228697636
Pubmed

FADS1 and FADS2 polymorphism are associated with changes in fatty acid concentrations after calorie-restricted Central European and Mediterranean diets.

FADS1 FADS2

1.47e-052134231567872
Pubmed

Carrying minor allele of FADS1 and haplotype of FADS1 and FADS2 increased the risk of metabolic syndrome and moderate but not low fat diets lowered the risk in two Korean cohorts.

FADS1 FADS2

1.47e-052134229779171
Pubmed

Toll-like receptor 2 controls the gamma interferon response to Francisella tularensis by mouse liver lymphocytes.

IL12A TLR2

1.47e-052134217785474
Pubmed

Mendelian randomization shows sex-specific associations between long-chain PUFA-related genotypes and cognitive performance in Danish schoolchildren.

FADS1 FADS2

1.47e-052134228515069
Pubmed

Erythrocyte polyunsaturated fatty acid composition is associated with depression and FADS genotype in Caucasians.

FADS1 FADS2

1.47e-052134228552045
Pubmed

Association of fatty acid desaturase genes with attention-deficit/hyperactivity disorder.

FADS1 FADS2

1.47e-052134216893529
Pubmed

Vitamin B-6 restriction impairs fatty acid synthesis in cultured human hepatoma (HepG2) cells.

FADS1 FADS2

1.47e-052134223211517
Pubmed

Single nucleotide polymorphisms in the FADS gene cluster are associated with delta-5 and delta-6 desaturase activities estimated by serum fatty acid ratios.

FADS1 FADS2

1.47e-052134220427696
Pubmed

Uncovering the DNA methylation landscape in key regulatory regions within the FADS cluster.

FADS1 FADS2

1.47e-052134228957329
Pubmed

Polyunsaturated fatty acid regulation of adipocyte FADS1 and FADS2 expression and function.

FADS1 FADS2

1.47e-052134225755223
Pubmed

Early nutrition in combination with polymorphisms in fatty acid desaturase gene cluster modulate fatty acid composition of cheek cells' glycerophospholipids in school-age children.

FADS1 FADS2

1.47e-052134231638497
Pubmed

Interaction of fatty acid genotype and diet on changes in colonic fatty acids in a Mediterranean diet intervention study.

FADS1 FADS2

1.47e-052134224022589
Pubmed

Toll-like receptor 2 and NALP2 mediate induction of human beta-defensins by fusobacterium nucleatum in gingival epithelial cells.

NLRP2 TLR2

1.47e-052134219103770
Pubmed

Lack of association of SNPs from the FADS1-FADS2 gene cluster with major depression or suicidal behavior.

FADS1 FADS2

1.47e-052134226513616
Pubmed

Association of two polymorphisms in the FADS1/FADS2 gene cluster and the risk of coronary artery disease and ischemic stroke.

FADS1 FADS2

1.47e-052134226261632
Pubmed

FADS1 and FADS2 Gene Polymorphisms Modulate the Relationship of Omega-3 and Omega-6 Fatty Acid Plasma Concentrations in Gestational Weight Gain: A NISAMI Cohort Study.

FADS1 FADS2

1.47e-052134235268031
Pubmed

Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults.

FADS1 FADS2

1.47e-052134221414826
Pubmed

Reduction of Arachidonate Is Associated With Increase in B-Cell Activation Marker in Infants: A Randomized Trial.

FADS1 FADS2

1.47e-052134227276431
Pubmed

Polymorphisms of rs174616 in the FADS1-FADS2 gene cluster is associated with a reduced risk of type 2 diabetes mellitus in northern Han Chinese people.

FADS1 FADS2

1.47e-052134225981324
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATP7A NOL11 MRPL28 RICTOR CHD1 HEATR1 MTPN TUBGCP6 GSTM3 SACS TEX264 FADS2 MACF1 IFT122 HERC2 SNRNP200 VPS13B SNX5

1.71e-0514871341833957083
Pubmed

FBXL13 directs the proteolysis of CEP192 to regulate centrosome homeostasis and cell migration.

NEB ADNP SACS AASS

2.10e-0542134429348145
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

ATP7A EPB41L4B RTTN RICTOR LMBRD2 RBSN GORASP2 CNPY3 SNU13 MACF1 TMEM39A HERC2

2.36e-057191341235337019
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

TRIO CENPF FRYL XPNPEP1 RBSN MACF1

2.75e-05151134617043677
Pubmed

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

IL12A THEMIS MALT1 FCRL3 TMEM39A

2.81e-0591134521833088
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

SESTD1 TRIO RAD54L2 GFPT1 MTPN STAB1 FOCAD GORASP2 SACS USP32 MACF1 DCLK2 IFT122 HERC2 SNRNP200 SNX5

3.73e-0512851341635914814
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

RASA2 LANCL1 MRPL28 NEB BCOR INTS3 GFPT1 PPP4R4 AASS FHIP2B DNAH11

3.90e-056381341131182584
Pubmed

A case-control study between gene polymorphisms of polyunsaturated fatty acid metabolic rate-limiting enzymes and acute coronary syndrome in Chinese Han population.

FADS1 FADS2

4.41e-053134223555103
Pubmed

Association of fatty acid desaturase gene polymorphisms with blood lipid essential fatty acids and perinatal depression among Canadian women: a pilot study.

FADS1 FADS2

4.41e-053134220395685
Pubmed

Placental expression of Fatty Acid Desaturases 1, 2 and 3 in selected pregnancy pathologies.

FADS1 FADS2

4.41e-053134236652541
Pubmed

[A case-control study between gene polymorphisms of polyunsaturated fatty acids metabolic rate-limiting enzymes and paranoid schizophrenia of Han ethnicity in Jilin Province].

FADS1 FADS2

4.41e-053134221560298
InteractionGPR17 interactions

VPS50 RNF213 HEATR1 COG3 LMBRD2 INTS3 FHIP2A NR2F2 MFN1 FADS1 SACS GEMIN4

3.35e-0728313112int:GPR17
InteractionCD70 interactions

HIP1R NOL11 HEATR1 INTS3 NR2F2 GK TEX264 GEMIN4

1.31e-051661318int:CD70
InteractionTACSTD2 interactions

RTTN HIP1R RNF213 COG3 INTS3 SACS GEMIN4

2.16e-051291317int:TACSTD2
InteractionSCN2B interactions

HIP1R RNF213 HEATR1 COG3 NR2F2 FOCAD

3.64e-05951316int:SCN2B
InteractionDUSP26 interactions

XPNPEP1 FANCI GEMIN4 HERC2 SNRNP200

4.06e-05591315int:DUSP26
InteractionGPR182 interactions

VPS50 HIP1R RNF213 HEATR1 COG3 LMBRD2 ENTPD4 NR2F2 FOCAD FADS1 FANCI SLC25A28

4.26e-0545513112int:GPR182
InteractionUBXN6 interactions

RICTOR INTS3 NLRP2 DIS3 TUBGCP6 GSTM3 USP32 IFT122 ANAPC5 VPS13B

5.34e-0532513110int:UBXN6
InteractionBAG2 interactions

RC3H1 RICTOR BCOR ADNP NR2F2 TUBGCP6 CCNF RNF214 EIF4ENIF1 TLE2 TLE4 IFT122 ANAPC5 VPS13B

5.44e-0562213114int:BAG2
InteractionHCST interactions

ATP7A RTTN RNF213 LMBRD2 MFN1 FOCAD GEMIN4 NCEH1

5.94e-052051318int:HCST
InteractionSLC2A9 interactions

VPS50 HIP1R GK SLC25A28

6.03e-05331314int:SLC2A9
GeneFamilyFatty acid desaturases

FADS1 FADS2

5.73e-048832553
GeneFamilyX-linked mental retardation|RNA helicases

HELQ SNRNP200

1.11e-03118321168
CoexpressionWILCOX_RESPONSE_TO_PROGESTERONE_UP

CENPF SGK1 HBP1 GK FADS1 FANCI FADS2

1.23e-051531317M18058
CoexpressionHE_LIM_SUN_FETAL_LUNG_C1_EARLY_STALK_CELL

CENPF SGK1 RTTN RAD54L2 POLA2 SPDL1 CCNF SACS FANCI STARD9 FADS2 RAD54L

2.87e-0556713112M45692
CoexpressionGSE11864_UNTREATED_VS_CSF1_IN_MAC_DN

THEMIS HBP1 SPDL1 RBSN SACS TEX264 IFT122

6.19e-051971317M3123
CoexpressionGSE25088_WT_VS_STAT6_KO_MACROPHAGE_IL4_STIM_DN

CENPF POLA2 FADS1 FANCI IFT122 CFAP70 RAD54L

6.60e-051991317M8029
CoexpressionGSE27786_NEUTROPHIL_VS_MONO_MAC_DN

NOL11 CHD1 NEB CCNF HOXC10 POLK SNX5

6.60e-051991317M4883
CoexpressionGSE18893_TCONV_VS_TREG_24H_CULTURE_DN

IL12A CENPF RNF213 PLXND1 SPDL1 IFIT1B DCLK2

6.81e-052001317M7289
CoexpressionGSE32986_UNSTIM_VS_CURDLAN_HIGHDOSE_STIM_DC_UP

EAF2 POLA2 GFPT1 CCNF GK CCNA1 IFT122

6.81e-052001317M8614
CoexpressionGSE17721_POLYIC_VS_PAM3CSK4_1H_BMDC_DN

CEP104 IL12A HIP1R CHD1 PFKFB1 TLR2 TMEM39A

6.81e-052001317M3826
CoexpressionGSE360_CTRL_VS_M_TUBERCULOSIS_DC_UP

TRIO LAMB2 PFKFB1 ADNP GORASP2 TLE4 SNU13

6.81e-052001317M5154
CoexpressionLI_WILMS_TUMOR_ANAPLASTIC_UP

CENPF CCNA1 RAD54L

7.88e-05171313M1215
ToppCellNS-moderate-d_07-13-Epithelial-FOXN4+|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CENPF RTTN FANCI IFT122 CFAP70 RAD54L DNAH11

4.99e-071571347410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

BCOR POLA2 PLA2G15 STAB1 FANCI RAD54L SNX5

5.43e-071591347c0e55f25271f788c08fa4b95186501fc27b2ec39
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RTTN RNF213 RICTOR FRYL MACF1 SNRNP200 VPS13B

2.43e-061991347f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC37A1 ATP7A ASB15 HELQ CFAP206 GNAT2

7.57e-061551346441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCell3'_v3-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

CENPF POLA2 CCNF FADS1 FANCI FADS2

1.01e-05163134647300dec94dc66e965bf71fafff0a9fd24fae968
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 SESTD1 DENND4A TRIO HIP1R FCRL3

1.01e-0516313466bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellfacs-Lung-EPCAM-24m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL11 ERLEC1 NR2F2 STAB1 FANCI TLE2

1.16e-051671346961e722442d786ab15d1e490941d2be265a9057a
ToppCellfacs-Lung-EPCAM-24m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL11 ERLEC1 NR2F2 STAB1 FANCI TLE2

1.16e-0516713463760efc35d4e7e9c2da1a20f9795ddea397e2206
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 SESTD1 DENND4A TRIO HIP1R FCRL3

1.42e-051731346d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

COG3 ENTPD4 MFN1 FADS1 USP32 SNRNP200

1.46e-0517413462274648b80dd74f3c948a779bba3391095964c34
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RGPD2 PLXND1 STAB1 GK TLR2 RAD54L

1.61e-051771346f28243b51be104cb3adcde63f03fc2206ed3121e
ToppCellPBMC-Mild-cDC_12|Mild / Compartment, Disease Groups and Clusters

CENPF HIP1R CCNF FANCI DCLK2 POGLUT2

2.33e-051891346946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell(2)_5-FU-(1)_VE-Cad+_vascular_cells|World / Stress and Cell class

SGK1 STAP2 PLXND1 NR2F2 STAB1 WDR89

2.40e-0519013466b391b8a3ffcbdec3acaf242bc52fc3fc9da77c8
ToppCellPBMC-Severe-cDC_12|Severe / Compartment, Disease Groups and Clusters

CENPF POLA2 FANCI CCNA1 FADS2 RAD54L

2.40e-05190134684ee185939bdefb10705b621a70da27701eadcee
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CENPF RTTN POLA2 CCNF FANCI RAD54L

2.62e-0519313464b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SGK1 LAMB2 PLXND1 STAB1 GK TLR2

3.03e-051981346a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CENPF PFKFB1 SPDL1 CCNF FANCI RAD54L

3.11e-051991346be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A GANC RTTN CCNF ZNF654

6.14e-0513813456b83c434895d82eaf3c222eef27acec76f9c0a77
ToppCellPND01-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CENPF BCOR SPDL1 STAB1 CCNF

7.03e-051421345be63c48794a227ea55978524c0f5935342fc455e
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_3|390C / Donor, Lineage, Cell class and subclass (all cells)

VIL1 PLA2G15 GK FCRLB NCEH1

9.69e-051521345f717aae4882e9b67e5e40f4ef5b0d35f74a89165
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF PLXND1 CCNF FANCI RAD54L

1.06e-041551345969fc4c98a96bf2f436e8e63d4deb2183ef3b864
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8|bone_marrow / Manually curated celltypes from each tissue

DENND4A RNF213 RICTOR CHD1 MACF1

1.09e-0415613451545169694f686d28648a68b552c2ae606599d66
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EAF2 BCOR CCNF GK TLR2

1.23e-0416013455d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THEMIS CENPF POLA2 SPDL1 CCNF

1.51e-041671345754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HIP1R PFKFB1 TLE4 VRTN DCLK2

1.55e-0416813458072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF SPDL1 CCNF FANCI RAD54L

1.59e-041691345b253a4a50c06d36228fcd5d856c57202cbac158f
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

ENTPD7 SESTD1 DIS3 GORASP2 CLDN16

1.68e-041711345adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

DENND4A THEMIS RNF213 CHD1 MACF1

1.68e-0417113452e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

IL12A CENPF PPP4R4 CCNF RAD54L

1.68e-041711345c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PLXND1 BCOR TUBGCP6 STARD9 SLC25A28

1.73e-041721345a9e13aa36087170dadca421ba9de588e5a1cf715
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

ENTPD7 RNF213 HEATR1 MFN1 POGLUT2

1.92e-0417613453de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ENTPD7 RGPD2 DENND4A TLR2 CFAP70

2.08e-04179134587f608b137aae34572b150492a83a3a127cff40b
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS RICTOR SPDL1 MALT1 SHISAL2A

2.08e-0417913456bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CENPF SPDL1 CCNF FANCI RAD54L

2.13e-041801345334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCelldroplet-Heart-4Chambers-21m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGK1 STAP2 PLXND1 WDR89 IFT122

2.36e-041841345f17d713af4a97dff4eeeab24c405677ef2ffcf84
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND4A CENPF NUDT4 IFIT1B USP32

2.42e-041851345e8f7da9641b6cf1db1093b4f301ce828fd3a529c
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

RNF213 FRYL HEATR1 LMBRD2 MACF1

2.42e-041851345a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

EAF2 CENPF CCNF FANCI RAD54L

2.42e-0418513459766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellLPS_only|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND4A RNF213 POLA2 SLC25A28 VPS13B

2.42e-041851345a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCelldroplet-Heart-nan-24m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGK1 STAP2 PLXND1 WDR89 IFT122

2.42e-04185134511a44006950f6ccade86a85d5f06696d2036ffde
ToppCelldroplet-Heart-nan-24m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGK1 STAP2 PLXND1 WDR89 IFT122

2.48e-0418613458b316bfed39b91c15d5ae28d9261eb057f113796
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

RNF213 FRYL HEATR1 LMBRD2 MACF1

2.48e-0418613458571956890fc9894d766ba294a28e376b4aba428
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CENPF STAB1 CCNF FANCI TLR2

2.54e-04187134573931a5ea73799095daff100b5f18853c57c74dc
ToppCellFetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STAB1 MALT1 GK TLE4 TLR2

2.61e-0418813453be2d50148daa4eddddc2c7f269f45c97f7e4931
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

DENND4A RNF213 RICTOR CHD1 MACF1

2.61e-041881345ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASA2 RNF213 FCRL3 TLE4 MACF1

2.61e-0418813459abd78970bbe4ed03b59a83da63bbd334712f605
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASA2 RNF213 FCRL3 TLE4 MACF1

2.61e-041881345f7dc29dfec68236883469e848be5db34f5526d6b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_ILC-NK_cell|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RASA2 RNF213 FCRL3 TLE4 MACF1

2.61e-0418813455ae8ccdd328cf117da1d01ced2c3b7f763a5f1f1
ToppCellEC-Sinusoidal_ECs|World / Lineage and Cell class

SGK1 STAP2 PLXND1 NR2F2 STAB1

2.67e-0418913459a0956c8a7069ba3bd0fa56d052d6e514453e578
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PLXND1 GK FADS1 APEX2 TLR2

2.67e-041891345a2f4f1dd5452f7efb7427919a0b90875cf2e1dc7
ToppCellPBMC-Convalescent-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PLXND1 GK FADS1 APEX2 TLR2

2.67e-04189134554a45b0cb7dea01caf1cf0a2664c40e5779a0b61
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THEMIS RASA2 RNF213 FCRL3 MACF1

2.74e-041901345d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellNS-moderate-d_16-33-Epithelial-FOXN4+|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CENPF RTTN FANCI IFT122 RAD54L

2.74e-041901345250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

CENPF POLA2 CCNF FANCI RAD54L

2.74e-041901345d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

RGPD2 DENND4A HIP1R RICTOR CHD1

2.81e-0419113451ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

THEMIS CENPF CCNF FANCI RAD54L

2.81e-041911345bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

RNF213 FRYL HEATR1 LMBRD2 MACF1

2.81e-0419113459454f642c3621370fa23640b631301346b300950
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

CENPF LAMB2 SPDL1 CCNF IFT122

2.87e-0419213459cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-D|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RGPD2 HBP1 NUDT4B PLA2G15 CNPY3

2.87e-041921345181d22fbb98a619a7f302c0f6623cee94c49a253
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GANC RC3H1 PFKFB1 EIF4ENIF1 AASS

2.87e-041921345d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCellControl-Lymphoid-Proliferating_CD4_T_cells|Control / Condition, Lineage and Cell class

CENPF SPDL1 CCNF FANCI RAD54L

2.94e-04193134533d409d6ed1c606337248587ad997ac5f67f081d
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

ENTPD7 FRYL BCOR USP32 VPS13B

2.94e-041931345abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_DZ|normal_Lymph_Node / Location, Cell class and cell subclass

EAF2 CENPF CCNF FANCI RAD54L

2.94e-0419313455ce93860bc60ce6ecfed3a3d985f84e28781eec1
ToppCellControl-Myeloid-cMonocyte|World / Disease state, Lineage and Cell class

CHD1 STAB1 MALT1 GK TLR2

3.01e-041941345f852f5258617a66a4fbd56d64c7b47272e7b8b60
ToppCell3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CENPF SPDL1 CCNF FANCI RAD54L

3.01e-0419413456cc689595a182fbf685fa2f3b9c300f7170fb81f
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-Cycling_plasma_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EAF2 CENPF SPDL1 CCNF FANCI

3.01e-04194134506b8dc2e46f833707d5b68b324b4ff6c4d0dccf9
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|367C / Donor, Lineage, Cell class and subclass (all cells)

CENPF SPDL1 CCNF FANCI RAD54L

3.01e-041941345a12b64945e10f00aa983678a02586c59badc1570
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

THEMIS CENPF CCNF FANCI RAD54L

3.09e-0419513457e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

THEMIS CENPF CCNF FANCI RAD54L

3.09e-041951345764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CENPF SPDL1 CCNF FANCI RAD54L

3.09e-041951345926eb3fc5d028be936885bea0654a77db3107234
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_anti-infl|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SGK1 PLXND1 STAB1 GK TLR2

3.09e-0419513450ec1b572bbb92b6da3440139366a4c1743b1ad92
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|343B / Donor, Lineage, Cell class and subclass (all cells)

EAF2 CENPF SPDL1 FANCI RAD54L

3.09e-04195134547a01b8a92eebeb34ac7f70bf1ab4613a326e24f
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-0419613456d80e23f6a1725a3f5ea7263233c55c2ea56f977
ToppCellBAL-Control-Myeloid-Myeloid|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-041961345bf1d3fae8c01bb3d17c2dafad92b94937c663acd
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_proliferating|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-0419613459591a6a3477ed6a1e2e016f7542e38603d8b16cb
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-0419613453dd7ed1dfac8d90c8a44f0ae00128bb46d9ef496
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-04196134573f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGK1 STAB1 MALT1 GK TLR2

3.16e-041961345c2bbb48c4aa979b03cb6f4ce9f351f492977c992
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-0419613454f649e3bfd21f21682678828673843a7d51c4ff2
ToppCellBAL-Control-Myeloid-Myeloid|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-041961345799c290fb3dfacb666dd0dc3c43ec8a86b697ec7
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

BCOR HELQ HOXC10 CFAP206 DNAH11

3.16e-0419613457e98380d815fbf6254289ace2af37aac6fef51e8
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SGK1 STAB1 MALT1 GK TLR2

3.16e-04196134564c2abc0087bf2ae547932377f3662e3be1cc63e
ToppCellBAL-Control-Myeloid-Myeloid-proliferating_Myeloid_cells|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CENPF SPDL1 CCNF FANCI RAD54L

3.16e-0419613450c003a767c3b58605099dab64b9df0d8e5d8bc4b
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A SGK1 RC3H1 HBP1 MTPN

3.16e-041961345151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGK1 PLXND1 NR2F2 STAB1 MACF1

3.23e-041971345deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCellControl-Myeloid-proliferating_Myeloid_cells|Control / Disease group,lineage and cell class （2021.01.30）

CENPF SPDL1 CCNF FANCI RAD54L

3.23e-041971345ddbe3fe078766bb55f0d7ca1aeb8f9e4aa696d8e
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGK1 PLXND1 NR2F2 STAB1 MACF1

3.23e-041971345a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCellHealthy_Control-Lymphoid-T-Proliferating_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CENPF SPDL1 CCNF FANCI RAD54L

3.23e-0419713453ce3dcbbe0edeb5a6fb5596dd6c2b4d6c1d5159d
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

RNF213 RICTOR CHD1 TLE4 SNU13

3.23e-041971345e666f6580e9a20b5e550f02125706db17eec8510
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

RASA2 CHD1 STAB1 GK TLR2

3.23e-041971345df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLITRK3 GRIN2A STARD9 DCLK2 DNAH11

3.31e-041981345c12e7511628db819a52959bb68580e27c00c2e41
ToppCelldistal-Hematologic-Proliferating_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CENPF SPDL1 CCNF FANCI RAD54L

3.31e-0419813458afeb1f9bc9d8551482c8fefe4c5f88d9cd13ee2
ToppCellCaecum-B_cell-B_cell_cycling|B_cell / Region, Cell class and subclass

CENPF SPDL1 FANCI POGLUT2 RAD54L

3.31e-041981345d2def132f3efe9305a5501a96ec82efb1f02c3f7
ToppCellHealthy_Control-Myeloid-Macrophages-FCN1+SPP1+|Healthy_Control / Condition, Lineage, Cell class and cell subclass

SESTD1 SGK1 GK TLR2 NCEH1

3.31e-041981345aa90326b82e21de37af5642df6a70a8b21af7f04
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

CENPF CCNF FADS1 FANCI RAD54L

3.31e-0419813455c92687b853ebb00960adbef6552f9d460bc6886
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Proliferating-cycling_dorsal_progenitors|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CENPF SPDL1 CCNF FANCI CCNA1

3.31e-041981345dada1c19a261c8e1090957cd7e37f2a43a9fe14f
ToppCellBAL-Severe|BAL / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SGK1 RNF213 STAB1 TLR2 MACF1

3.31e-041981345454aee3f4fe6d0beeccc55200b4495f4f9b44feb
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CENPF POLA2 SPDL1 CCNF FANCI

3.31e-041981345281fc2536cdc4c717b30de156e563c0e4baba99d
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SGK1 PLXND1 STAB1 GK TLR2

3.31e-041981345d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SGK1 PLXND1 NR2F2 STAB1 MACF1

3.31e-041981345f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
Drugphosphonoacetic acid

SLC37A1 VIL1 EAF2 LANCL1 POLA2 SNU13 POLK

1.20e-06941317CID000000546
Diseaseprocollagen C-endopeptidase enhancer 1 measurement

FADS1 FADS2 DNAH11

1.47e-0661253EFO_0801920
Diseaselevel of Sterol ester (27:1/20:5) in blood serum

NWD2 FADS1 FADS2

1.19e-05111253OBA_2045197
Diseasefatty acid measurement, fetal genotype effect measurement, breast milk measurement

COG3 FADS1 FADS2

2.06e-05131253EFO_0005110, EFO_0007959, EFO_0009092
Diseasefatty acid measurement, breast milk measurement, parental genotype effect measurement

COG3 FADS1 FADS2

2.61e-05141253EFO_0005110, EFO_0005939, EFO_0009092
Diseasefree cholesterol to total lipids in small HDL percentage

RNF214 FADS1 FADS2 POLK

6.57e-05511254EFO_0022285
DiseasePalmitoyl-arachidonoyl-glycerol (16:0/20:4) [2] measurement

FADS1 FADS2

1.06e-0441252EFO_0022103
DiseaseSphingomyelin (d18:2/14:0, d18:1/14:1) measurement

FADS1 FADS2

1.06e-0441252EFO_0022114
Disease2-arachidonoylglycerol (20:4) measurement

FADS1 FADS2

1.06e-0441252EFO_0800182
Disease2-linoleoyl-GPC (18:2) measurement

FADS1 FADS2

1.06e-0441252EFO_0800239
Disease1-dihomo-linoleoyl-GPC (20:2) measurement

FADS1 FADS2

1.06e-0441252EFO_0800236
Diseasedocosapentaenoate (n6 DPA; 22:5n6) measurement

FADS1 FADS2

1.06e-0441252EFO_0800249
Disease1-linoleoyl-2-docosahexaenoyl-GPC (18:2/22:6) measurement

FADS1 FADS2

1.06e-0441252EFO_0022080
Disease1-margaroyl-2-arachidonoyl-GPC (17:0/20:4) measurement

FADS1 FADS2

1.06e-0441252EFO_0022081
Disease1-arachidoyl-2-arachidonoyl-GPC (20:0/20:4) measurement

FADS1 FADS2

1.06e-0441252EFO_0022079
Diseasephosphatidylcholine (O-18:1/20:4, O-16:0/22:5n3) measurement

FADS1 FADS2

1.06e-0441252EFO_0800553
Diseasearachidonate 20:4n6-to-dihomo-linolenate 20:3n3 or n6 ratio

FADS1 FADS2

1.06e-0441252EFO_0021517
Diseasefatty acid measurement, linolenic acid measurement

FADS1 FADS2

1.06e-0441252EFO_0005110, EFO_0006811
Diseasephosphatidylcholine acyl-alkyl C38:5 measurement

FADS1 FADS2

1.06e-0441252EFO_0801299
Diseasephosphatidylcholine acyl-alkyl C36:4 measurement

FADS1 FADS2

1.06e-0441252EFO_0801292
Diseasephosphatidylcholine acyl-alkyl C36:2 measurement

FADS1 FADS2

1.06e-0441252EFO_0801290
Diseasephosphatidylcholine diacyl C38:5 measurement

FADS1 FADS2

1.06e-0441252EFO_0801267
Diseasephosphatidylcholine diacyl C38:4 measurement

FADS1 FADS2

1.06e-0441252EFO_0801266
Diseasephosphatidylcholine diacyl C36:4 measurement

FADS1 FADS2

1.06e-0441252EFO_0801260
Diseasephosphatidylcholine diacyl C40:6 measurement

FADS1 FADS2

1.06e-0441252EFO_0801274
Diseasephosphatidylcholine diacyl C36:3 measurement

FADS1 FADS2

1.06e-0441252EFO_0801259
Diseasephosphatidylcholine diacyl C34:4 measurement

FADS1 FADS2

1.06e-0441252EFO_0801255
Diseaselevel of Phosphatidylcholine (O-16:0_22:5) in blood serum

FADS1 FADS2

1.06e-0441252OBA_2045117
Diseasesphingomyeline C16:1 measurement

FADS1 FADS2

1.06e-0441252EFO_0801318
Disease1-linoleoyl-2-linolenoyl-GPC (18:2/18:3) measurement

FADS1 FADS2

1.06e-0441252EFO_0800483
Diseaseeicosapentaenoylcholine measurement

FADS1 FADS2

1.06e-0441252EFO_0800482
Diseasecomprehensive strength index, muscle measurement

FADS1 FADS2

1.06e-0441252EFO_0004515, EFO_0004979
Disease1-stearoyl-2-adrenoyl-GPC (18:0/22:4) measurement

FADS1 FADS2

1.06e-0441252EFO_0800459
Disease1-palmitoyl-2-meadoyl-GPC (16:0/20:3n9) measurement

FADS1 FADS2

1.06e-0441252EFO_0800458
Diseasephosphatidylcholine (18:0/20:5, 16:0/22:5n6) measurement

FADS1 FADS2

1.06e-0441252EFO_0800468
Disease1-stearoyl-2-meadoyl-GPC (18:0/20:3n9) measurement

FADS1 FADS2

1.06e-0441252EFO_0800463
Disease1-pentadecanoyl-2-arachidonoyl-GPC (15:0/20:4) measurement

FADS1 FADS2

1.06e-0441252EFO_0800446
Disease1-palmitoyl-2-alpha-linolenoyl-GPC (16:0/18:3n3) measurement

FADS1 FADS2

1.06e-0441252EFO_0800442
Disease1-palmitoyl-2-eicosapentaenoyl-GPC (16:0/20:5) measurement

FADS1 FADS2

1.06e-0441252EFO_0800408
Diseasephosphatidylcholine 33:2 measurement

FADS1 FADS2

1.06e-0441252EFO_0021470
Diseasephosphatidylcholine 33:1 measurement

FADS1 FADS2

1.06e-0441252EFO_0021469
Disease1,2-dilinoleoyl-GPC (18:2/18:2) measurement

FADS1 FADS2

1.06e-0441252EFO_0800388
Disease1-eicosapentaenoyl-GPC (20:5) measurement

FADS1 FADS2

1.06e-0441252EFO_0800355
Disease1-(1-enyl-stearoyl)-GPC (P-18:0) measurement

FADS1 FADS2

1.06e-0441252EFO_0800325
Disease1-(1-enyl-oleoyl)-GPC (P-18:1) measurement

FADS1 FADS2

1.06e-0441252EFO_0800324
Disease1-lignoceroyl-GPC (24:0) measurement

FADS1 FADS2

1.06e-0441252EFO_0800322
Disease1-adrenoyl-GPC (22:4) measurement

FADS1 FADS2

1.06e-0441252EFO_0800321
Disease2-arachidonoyl-GPC (20:4) measurement

FADS1 FADS2

1.77e-0451252EFO_0800237
Disease1-arachidonoyl-GPC (20:4n6) measurement

FADS1 FADS2

1.77e-0451252EFO_0800234
Disease1-linoleoyl-GPC (18:2) measurement

FADS1 FADS2

1.77e-0451252EFO_0800223
Diseasefatty acid measurement, docosapentaenoic acid measurement

FADS1 FADS2

1.77e-0451252EFO_0005110, EFO_0006809
Diseasephosphatidylcholine acyl-alkyl C36:5 measurement

FADS1 FADS2

1.77e-0451252EFO_0801293
Diseasesphingomyeline C18:1 measurement

FADS1 FADS2

1.77e-0451252EFO_0801320
Disease1-palmitoleoyl-2-linolenoyl-GPC (16:1/18:3) measurement

FADS1 FADS2

1.77e-0451252EFO_0800484
Diseasephosphatidylcholine (16:0/22:5n3, 18:1/20:4) measurement

FADS1 FADS2

1.77e-0451252EFO_0800467
Disease1-(1-enyl-stearoyl)-2-arachidonoyl-GPE (P-18:0/20:4) measurement

FADS1 FADS2

1.77e-0451252EFO_0800415
Disease1-palmitoyl-2-dihomo-linolenoyl-GPC (16:0/20:3n3 or 6) measurement

FADS1 FADS2

1.77e-0451252EFO_0800407
Disease1-(1-enyl-palmitoyl)-2-arachidonoyl-GPE (P-16:0/20:4) measurement

FADS1 FADS2

1.77e-0451252EFO_0800417
Disease1-linolenoyl-GPE (18:3) measurement

FADS1 FADS2

1.77e-0451252EFO_0800365
Disease1-(1-enyl-stearoyl)-GPE (P-18:0) measurement

FADS1 FADS2

1.77e-0451252EFO_0800335
Diseaselysophosphatidylethanolamine 18:2 measurement

LMBRD2 FADS1 FADS2

1.80e-04261253EFO_0010369
Diseasemean corpuscular hemoglobin concentration

VIL1 DENND4A RTTN MRPL28 XPNPEP1 NEB FOCAD FADS1 NUDT4 FADS2 MACF1 SLC25A28 ZNF654 VPS13B

2.53e-04110512514EFO_0004528
DiseaseSphingomyelin (d18:1/20:1, d18:2/20:0) measurement

FADS1 FADS2

2.64e-0461252EFO_0022110
DiseaseSphingomyelin (d18:1/18:1, d18:2/18:0) measurement

FADS1 FADS2

2.64e-0461252EFO_0022108
Disease1-stearoyl-GPC (18:0) measurement

FADS1 FADS2

2.64e-0461252EFO_0800217
Disease1-arachidonylglycerol (20:4) measurement

FADS1 FADS2

2.64e-0461252EFO_0800224
Diseasecontactin-1 measurement

MUC19 MRPL28

2.64e-0461252EFO_0020286
Diseasearachidonic acid measurement, fatty acid measurement

FADS1 FADS2

2.64e-0461252EFO_0005110, EFO_0006808
Diseaseadrenate 22:4n6 measurement

FADS1 FADS2

2.64e-0461252EFO_0021062
Disease1-arachidonoylglycerophosphocholine measurement

FADS1 FADS2

2.64e-0461252EFO_0021076
Diseasedihomo-linolenate 20:3n3 or n6 measurement

FADS1 FADS2

2.64e-0461252EFO_0021046
Diseasedocosapentaenoate n3 DPA; 22:5n3 measurement

FADS1 FADS2

2.64e-0461252EFO_0021048
Disease1-linoleoylglycerophosphoethanolamine measurement

FADS1 FADS2

2.64e-0461252EFO_0021084
Diseaselevel of Phosphatidylcholine (18:2_0:0) in blood serum

FADS1 FADS2

2.64e-0461252OBA_2045105
Disease1-(1-enyl-stearoyl)-2-arachidonoyl-GPC (P-18:0/20:4) measurement

FADS1 FADS2

2.64e-0461252EFO_0800394
Disease1-palmitoyl-2-arachidonoyl-GPC (16:0/20:4n6) measurement

FADS1 FADS2

2.64e-0461252EFO_0800390
Diseaselevel of Phosphatidylcholine (O-18:2_18:2) in blood serum

FADS1 FADS2

2.64e-0461252OBA_2045134
Diseaselevel of Phosphatidylcholine (O-16:0_18:2) in blood serum

FADS1 FADS2

2.64e-0461252OBA_2045114
Diseasearachidonoylcholine measurement

FADS1 FADS2

2.64e-0461252EFO_0800478
Disease1-oleoyl-2-docosahexaenoyl-GPE (18:1/22:6) measurement

FADS1 FADS2

2.64e-0461252EFO_0800471
Disease1-stearoyl-2-dihomo-linolenoyl-GPC (18:0/20:3n3 or 6) measurement

FADS1 FADS2

2.64e-0461252EFO_0800434
Diseaselevel of Phosphatidylinositol (18:1_18:2) in blood serum

FADS1 FADS2

2.64e-0461252OBA_2045160
Disease1-palmitoyl-2-dihomo-linolenoyl-GPE (16:0/20:3) measurement

FADS1 FADS2

2.64e-0461252EFO_0800444
Disease1-palmityl-2-arachidonoyl-GPC (O-16:0/20:4) measurement

FADS1 FADS2

2.64e-0461252EFO_0800426
Disease1-stearoyl-2-linoleoyl-GPC (18:0/18:2) measurement

FADS1 FADS2

2.64e-0461252EFO_0800404
Diseaselysophosphatidylcholine 18:3 measurement

FADS1 FADS2

2.64e-0461252EFO_0021454
Disease1-docosapentaenoyl-GPC (22:5n3) measurement

FADS1 FADS2

2.64e-0461252EFO_0800298
Disease1-(1-enyl-palmitoyl)-GPC (P-16:0) measurement

FADS1 FADS2

2.64e-0461252EFO_0800323
Diseaselevel of Phosphatidylcholine (18:0_20:2) in blood serum

FADS1 FADS2

2.64e-0461252OBA_2045092
Disease1-(1-enyl-stearoyl)-2-linoleoyl-GPE (P-18:0/18:2)* measurement

FADS1 FADS2

2.64e-0461252EFO_0020014
Diseaseage at menopause

ZNF729 FRYL ADNP HELQ GORASP2 FANCI TLE4

3.13e-043021257EFO_0004704
DiseaseManic

GRIN2A STAB1 STARD9 FADS2

3.44e-04781254C0338831
Diseasebipolar I disorder

XPNPEP1 GRIN2A FADS1 STARD9 FADS2

3.44e-041411255EFO_0009963
DiseaseX-24870 measurement

FADS1 FADS2

3.69e-0471252EFO_0022143
Disease1,2-dipalmitoyl-GPC (16:0/16:0) measurement

FADS1 FADS2

3.69e-0471252EFO_0800189
Disease1-arachidonoyl-GPI (20:4) measurement

FADS1 FADS2

3.69e-0471252EFO_0800256
Disease1-linoleoyl-GPI (18:2) measurement

FADS1 FADS2

3.69e-0471252EFO_0800266
Disease1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) measurement

FADS1 FADS2

3.69e-0471252EFO_0800609
Diseaseeicosapentaenoate (EPA; 20:5n3) measurement

FADS1 FADS2

3.69e-0471252EFO_0800616
Diseaselevel of Sterol ester (27:1/22:6) in blood serum

FADS1 FADS2

3.69e-0471252OBA_2045201
Diseasearachidonate 20:4n6 measurement

FADS1 FADS2

3.69e-0471252EFO_0021063

Protein segments in the cluster

PeptideGeneStartEntry
KILSDIGLEYCKEHI

ADNP

21

Q9H2P0
ELPYLKCPLHTVLKL

PFKFB1

411

P16118
TAHKEKYKCILPLVT

ERLEC1

71

Q96DZ1
ELAETCQPYKKKHLV

CXorf66

261

Q5JRM2
LIKSDSPCFKEHEYT

ALLC

26

Q8N6M5
YVLHPLVAKACITNK

AASS

556

Q9UDR5
DYVPLCAKLKSALEV

ASB15

506

Q8WXK1
CDEYDSILAEHPLKL

CLDN16

61

Q9Y5I7
LTILFDKYVPACLDK

DNAH11

2346

Q96DT5
KESVLQLACLKYPHL

RAD54L2

926

Q9Y4B4
KEKTLTLINVYCPHA

APEX2

146

Q9UBZ4
PHYSELTNLKVCIEL

BCOR

1186

Q6W2J9
LIKIGDHITECLKEY

CHD1

1451

O14646
ILPDEYKSCLRHKRS

ADAMTS16

266

Q8TE57
HPLGTAITKYCKQEL

ATP7A

1086

Q04656
DADKHYIKPITKCES

CFAP206

501

Q8IYR0
LVQSYPKKIHDLCDL

NWD2

481

Q9ULI1
LILSSEHCNKYSKIP

DENND4A

1691

Q7Z401
KCVEELALYLKPLSS

RC3H1

101

Q5TC82
LEAKLDKPTVVHYLC

PLA2G15

51

Q8NCC3
HTPDIVKLYEKLRLC

RBSN

271

Q9H1K0
HYLKVTLKPILDEIC

RASA2

416

Q15283
TSLKKLCNHPALIYD

RAD54L

451

Q92698
KLKALHVDSAEYSCL

NR2F2

301

P24468
HLKYKEHPEALSCLL

INTS3

831

Q68E01
KLHTLIPCKKFDLSY

MFN1

491

Q8IWA4
LHGKSLTVIPYKCEV

NOL11

321

Q9H8H0
SKLYKLIEESCPQLA

ANAPC5

76

Q9UJX4
PLVKSLCAKHGIEYQ

FADS2

401

O95864
KLVKLSGSHLTPLCY

FANCI

1196

Q9NVI1
EPLLLCATYLKKLDS

IFT122

806

Q9HBG6
NPTCHLYDLVSKLKL

MAGEB5

101

Q9BZ81
SLIETHEAKPLKLYV

GORASP2

151

Q9H8Y8
HSLVKPSVDYVCQLK

LANCL1

241

O43813
VKKHKETPLYILCTA

ENTPD7

161

Q9NQZ7
DPKEILHSVYECIEK

GK3P

56

Q14409
KDLPKHCLYTRLSSL

MALT1

661

Q9UDY8
VHAEYLEKLKLGCSP

NUDT4B

136

A0A024RBG1
KYTALLCTHIGDILP

HERC2

1091

O95714
LPDYELKLIHHDSKC

GABBR1

206

Q9UBS5
LLVCEYPDGTKSLKL

DCLK2

521

Q8N568
SYPKLRSCKSDSHLL

FSIP2

636

Q5CZC0
EILDYKLPSCFKEHL

FSIP2

4086

Q5CZC0
LQYSPEKSSHIILAC

HARBI1

281

Q96MB7
KDLDTEKYFHLVLPT

PLXND1

1666

Q9Y4D7
HKILETLCTLGKAEY

FHIP2B

86

Q86V87
ESELPHKLYVLLFAK

OR2M2

311

Q96R28
HAEYLEKLKLGCSPA

NUDT4

136

Q9NZJ9
KLSLTLHKQYPTCGL

MUC19

591

Q7Z5P9
LLPKTYILTCEHDVL

NCEH1

336

Q6PIU2
RKKHSLALYPLITCL

FRYL

306

O94915
HYPSKCVVEKILVLG

GANC

851

Q8TET4
CYEKLKKTLSDVIHP

SLC25A28

151

Q96A46
YPLADAHLTKKLLDL

SNU13

11

P55769
VCLEPGISYKLHLKL

LAMB2

681

P55268
EHYPVLLSLLKTSCE

TUBGCP6

516

Q96RT7
IRLCYSSDHEKLKPQ

GSTM3

116

P21266
EGAKLLYTTLRHPKC

NLRP2

826

Q9NX02
PDFYKTKIKLCILLH

IL12A

186

P29459
CHETGLLTIKEKYPQ

RICTOR

1631

Q6R327
VSLTHPYSECDFKLK

MACF1

2886

Q9UPN3
PISIVKGELHKYCTA

SLC37A1

41

P57057
LEVLAEKCPNLTHLY

ANP32C

76

O43423
YIPKHKLSKLETAHC

CEP104

511

O60308
VKLLFKLHSCLPADT

HIP1R

231

O75146
KPYLKECILIINHDT

EAF2

81

Q96CJ1
LDKYCSLLISHEKLE

CENPF

2861

P49454
SYEDLIPCVLSLHKK

CCNF

481

P41002
YLDSVVHEKTKCLLS

CFAP70

366

Q5T0N1
LAKLDDCITYISSHP

COG3

226

Q96JB2
ETICKRLLDYSLHKE

CNPY3

101

Q9BT09
LSEIVPCLSELHKAY

CCNA1

416

P78396
IHKLKGEVSDALLCY

IFIT1B

446

Q5T764
DPKEILHSVYECIEK

GK

56

P32189
LCAKHGIEYQSKPLL

FADS1

406

O60427
CVDKYHVKVLRPESL

DNAH14

3011

Q0VDD8
KRCPYTKHQTLELEK

HOXC10

271

Q9NYD6
EELTVLYSELKKTHP

FCRL3

686

Q96P31
LLTVECKLDHPFYVK

HBP1

291

O60381
VPLAKGTLITHCYKD

HEATR1

171

Q9H583
TLKCDGYHPLLLELQ

FCRLB

41

Q6BAA4
VLELITKPLENCYSH

HELQ

731

Q8TDG4
KILETLYTLGKADCP

FHIP2A

86

Q5W0V3
KLCHNASLDDVLPIY

HHIPL2

476

Q6UWX4
KIHLKELYEVIGCVP

SACS

3456

Q9NZJ4
RHDILSGKLKCPYET

EPB41L4B

186

Q9H329
SHTIILKNLCLELYP

PRAMEF26

306

H0Y7S4
DHQKLSYKLVCPVTS

FOCAD

396

Q5VW36
SHSPLTKPLDICVKY

RTTN

1281

Q86VV8
HTKKALVPFLLDEDY

STAP2

236

Q9UGK3
LLQKYACLPHVISSD

PPP4R4

506

Q6NUP7
HYATCLEGALKIKEI

GFPT1

566

Q06210
ESIKYNHPLRKCVDT

LMBRD2

256

Q68DH5
GSPAIYKLKEHLLDC

RGPD2

126

P0DJD1
RAKHKETPLYILCTA

ENTPD4

166

Q9Y227
EKIKKVHLSICFPEY

GNAT2

276

P19087
SYACKHPEVQSILKI

SGK1

46

O00141
DCLYGTVPKLKELHV

SLITRK3

901

O94933
ETCKKLHPILYVSSK

SPDL1

581

Q96EA4
CYLFISSKPHTKLDL

SHISAL2A

86

Q6UWV7
SLSCVYAKALIEPLK

STARD9

1111

Q9P2P6
LKEHYKIEAFTPLLA

POLA2

231

Q14181
YPELTDKHKLADICK

DIS3

801

Q9Y2L1
TLDYLLSIPSEKCKA

SESTD1

46

Q86VW0
CPHRYTKEELLDIKE

EIF4ENIF1

26

Q9NRA8
HSLPCFIEKDLKEAL

C12orf4

51

Q9NQ89
SPSYLTVCLKLHEAI

RNF213

841

Q63HN8
EKEAELHLTYLKSTP

RNF214

371

Q8ND24
EVIHDKKQYPISELC

THEMIS

436

Q8N1K5
KLQYKDLCTHVTPDS

VPS50

306

Q96JG6
EPALKAALKLYHVSD

VIL1

246

P09327
SILSSELLDHPYCKS

SENP5

451

Q96HI0
HPYKSILSELKALCA

XPNPEP1

266

Q9NQW7
VYEGHVSCVKLLLSK

MTPN

76

P58546
KPDKYQLHLHESCVL

TLE4

691

Q04727
QLLPSKYCDLLHKSA

TMEM39A

336

Q9NV64
YEAHPKIKEISSVDC

POLK

686

Q9UBT6
IKSCINHPEISKDLY

ZNF654

216

Q8IZM8
LHDDPKTKCLIYKTI

ZNF654

366

Q8IZM8
KTKCLIYKTIAHFLP

ZNF654

371

Q8IZM8
VHPALDTYIKERKLC

TEX264

151

Q9Y6I9
CVYIHDPTGLNVLKK

STAB1

691

Q9NY15
LDFYILKTPKEDLCS

MRPL28

141

Q13084
LHSLALEEPTVIKKY

SNX5

251

Q9Y5X3
IIQCLLTHSGKKPYV

ZNF705EP

131

A8MWA4
CPIKKAASYHREILE

TRIM60

131

Q495X7
KHYIPVKSNLSDLLE

POGLUT2

406

Q6UW63
HCTEKDLIPYLEKLS

SNRNP200

1591

O75643
PRSKHLTGECKDLIY

TSSK1B

236

Q9BXA7
LCLPQIKIISAGHKY

VPS13B

1116

Q7Z7G8
HFDCLTAKQKLPSYI

VPS13B

2761

Q7Z7G8
HQISSYPDCKTKDLL

VPS13B

3296

Q7Z7G8
LHIVKCSLGTKEPTY

WDR89

11

Q96FK6
KLYLEHCISLNTLVP

VRTN

406

Q9H8Y1
KPEKYQLHLHESCVL

TLE2

661

Q04725
VPCLLSQHLKSLEYL

TLR2

351

O60603
IVPCTVHTRKKDLYD

USP32

1106

Q8NFA0
YCKNKPDSTQLILEH

TRIO

1386

O75962
LLDKTIHTGEKPYKC

ZNF729

1231

A6NN14
HLILECYADLSLPGK

GEMIN4

481

P57678
KIHSSVILLYCSKDE

GRIN2A

221

Q12879
KCQILVSDIDYKHPL

NEB

3586

P20929