Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionEH domain binding

EPN3 SYNJ1

7.04e-0521682GO:1990175
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 TBC1D9B DOCK11 ASAP3 RGPD1 TBC1D9 GNA13 RABGAP1L RABGEF1 AKAP13 ARHGAP45 AGAP1 AGAP3 SOS2

1.02e-0450716814GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 TBC1D9B DOCK11 ASAP3 RGPD1 TBC1D9 GNA13 RABGAP1L RABGEF1 AKAP13 ARHGAP45 AGAP1 AGAP3 SOS2

1.02e-0450716814GO:0030695
DomainVWFA

COL6A1 CPNE8 CPNE9 COL28A1 ITGAM PARP4

9.33e-05821676PS50234
DomainVWA

COL6A1 CPNE8 CPNE9 COL28A1 ITGAM PARP4

1.07e-04841676SM00327
DomainVWF_A

COL6A1 CPNE8 CPNE9 COL28A1 ITGAM PARP4

2.63e-04991676IPR002035
DomainZF_DAG_PE_1

PRKD2 CDC42BPB AKAP13 PRKCZ ARHGAP45

2.68e-04641675PS00479
DomainZF_DAG_PE_2

PRKD2 CDC42BPB AKAP13 PRKCZ ARHGAP45

2.68e-04641675PS50081
DomainC1

PRKD2 CDC42BPB AKAP13 PRKCZ ARHGAP45

2.88e-04651675SM00109
DomainPE/DAG-bd

PRKD2 CDC42BPB AKAP13 PRKCZ ARHGAP45

3.10e-04661675IPR002219
DomainFN3

CNTN4 LRFN1 TNC MYOM3 OBSL1 LRFN5 ASTN1 ROS1

4.31e-041991678PS50853
DomainG8_domain

PKHD1L1 PKHD1

4.71e-0441672IPR019316
DomainG8

PKHD1L1 PKHD1

4.71e-0441672PS51484
DomainAlpha_catenin

CTNNA3 CTNNA1

4.71e-0441672IPR001033
DomainClathrin_a/coatomer_app_sub_C

COPG2 AP2A2

4.71e-0441672IPR015873
DomainG8

PKHD1L1 PKHD1

4.71e-0441672SM01225
DomainVINCULIN_1

CTNNA3 CTNNA1

4.71e-0441672PS00663
DomainG8

PKHD1L1 PKHD1

4.71e-0441672PF10162
DomainVinculin_CS

CTNNA3 CTNNA1

4.71e-0441672IPR000633
Domain-

COPG2 AP2A2

4.71e-04416723.30.310.30
DomainFN3_dom

CNTN4 LRFN1 TNC MYOM3 OBSL1 LRFN5 ASTN1 ROS1

5.96e-042091678IPR003961
DomainFlavin_mOase

FMO2 FMO4

7.81e-0451672IPR000960
DomainVinculin

CTNNA3 CTNNA1

7.81e-0451672PF01044
DomainDiMe-aniline_mOase

FMO2 FMO4

7.81e-0451672IPR012143
DomainFMO-like

FMO2 FMO4

7.81e-0451672PF00743
DomainFlavin_mOase-like

FMO2 FMO4

7.81e-0451672IPR020946
DomainDAG/PE-bd

PRKD2 CDC42BPB PRKCZ

8.30e-04211673IPR020454
DomainARM-type_fold

DOCK1 MROH9 DOCK11 RANBP6 TOGARAM1 COPG2 FMNL2 AP2A2 USP35 DAAM1

9.72e-0433916710IPR016024
DomainPH

PRKD2 DOCK11 ASAP3 CDC42BPB AKAP13 AGAP1 AGAP3 SOS2

1.08e-032291678PF00169
DomainPbH1

PKHD1L1 PKHD1

1.16e-0361672SM00710
DomainPbH1

PKHD1L1 PKHD1

1.16e-0361672IPR006626
DomainEGF

TNC LAMC1 TECTA CELSR1 TENM4 ASTN1 ADGRE1 MASP2

1.27e-032351678SM00181
DomainIGc2

GP6 CNTN4 LRFN1 MYOM3 OBSL1 HEPACAM LRFN5 UNC5D

1.27e-032351678SM00408
DomainIg_sub2

GP6 CNTN4 LRFN1 MYOM3 OBSL1 HEPACAM LRFN5 UNC5D

1.27e-032351678IPR003598
DomainFN3

CNTN4 LRFN1 TNC MYOM3 OBSL1 ASTN1 ROS1

1.40e-031851677SM00060
DomainVWA

COL6A1 COL28A1 ITGAM PARP4

1.58e-03561674PF00092
DomainPH_dom-like

PRKD2 DOCK11 ASAP3 RGPD1 CDC42BPB RABGAP1L AKAP13 PLCB2 AGAP1 AGAP3 SOS2

1.60e-0342616711IPR011993
DomainSTAT_TF_DNA-bd_sub

STAT5A STAT5B

1.62e-0371672IPR012345
DomainSTAT

STAT5A STAT5B

1.62e-0371672IPR001217
DomainVinculin/catenin

CTNNA3 CTNNA1

1.62e-0371672IPR006077
DomainSTAT_int

STAT5A STAT5B

1.62e-0371672SM00964
DomainSTAT_TF_DNA-bd

STAT5A STAT5B

1.62e-0371672IPR013801
DomainSTAT_bind

STAT5A STAT5B

1.62e-0371672PF02864
DomainSTAT_int

STAT5A STAT5B

1.62e-0371672PF02865
Domain-

STAT5A STAT5B

1.62e-03716721.10.532.10
DomainSTAT_alpha

STAT5A STAT5B

1.62e-0371672PF01017
Domain-

STAT5A STAT5B

1.62e-03716721.20.1050.20
DomainSTAT_TF_prot_interaction

STAT5A STAT5B

1.62e-0371672IPR013799
DomainSTAT_TF_coiled-coil

STAT5A STAT5B

1.62e-0371672IPR015988
Domain-

STAT5A STAT5B

1.62e-03716722.60.40.630
DomainIg_I-set

CNTN4 LRFN1 MYOM3 OBSL1 HEPACAM LRFN5 UNC5D

1.63e-031901677IPR013098
DomainI-set

CNTN4 LRFN1 MYOM3 OBSL1 HEPACAM LRFN5 UNC5D

1.63e-031901677PF07679
DomainEGF-like_dom

TNC LAMC1 TECTA CELSR1 TENM4 ASTN1 ADGRE1 MASP2

1.83e-032491678IPR000742
DomainDAD_dom

FMNL2 DAAM1

2.15e-0381672IPR014767
DomainSTAT_TF_alpha

STAT5A STAT5B

2.15e-0381672IPR013800
DomainDAD

FMNL2 DAAM1

2.15e-0381672PS51231
DomainPectin_lyase_fold/virulence

PKHD1L1 PKHD1

2.15e-0381672IPR011050
DomainCoatomer/calthrin_app_sub_C

COPG2 AP2A2

2.15e-0381672IPR009028
DomainArfGap

ASAP3 AGAP1 AGAP3

2.16e-03291673SM00105
DomainARFGAP

ASAP3 AGAP1 AGAP3

2.16e-03291673PS50115
DomainArfGap

ASAP3 AGAP1 AGAP3

2.16e-03291673PF01412
DomainArfGAP

ASAP3 AGAP1 AGAP3

2.16e-03291673IPR001164
DomainCopine

CPNE8 CPNE9

2.75e-0391672PF07002
DomainDrf_GBD

FMNL2 DAAM1

2.75e-0391672PF06371
DomainDrf_FH3

FMNL2 DAAM1

2.75e-0391672PF06367
DomainZU5

ANK1 UNC5D

2.75e-0391672SM00218
DomainFH3_dom

FMNL2 DAAM1

2.75e-0391672IPR010472
DomainGTPase-bd

FMNL2 DAAM1

2.75e-0391672IPR010473
DomainCopine

CPNE8 CPNE9

2.75e-0391672IPR010734
DomainDrf_FH3

FMNL2 DAAM1

2.75e-0391672SM01139
DomainDrf_GBD

FMNL2 DAAM1

2.75e-0391672SM01140
Domain-

PRKD2 DOCK11 ASAP3 RGPD1 CDC42BPB RABGAP1L AKAP13 AGAP1 AGAP3 SOS2

2.78e-03391167102.30.29.30
DomainDeath

ANK1 IRAK1 UNC5D

3.15e-03331673PF00531
Domainfn3

CNTN4 LRFN1 TNC MYOM3 OBSL1 ROS1

3.39e-031621676PF00041
DomainZU5

ANK1 UNC5D

3.41e-03101672PS51145
DomainGPS

ADGRG4 CELSR1 ADGRE1

3.43e-03341673SM00303
DomainPH

PRKD2 DOCK11 ASAP3 CDC42BPB AKAP13 AGAP1 AGAP3 SOS2

3.61e-032781678SM00233
DomainPH_DOMAIN

PRKD2 DOCK11 ASAP3 CDC42BPB AKAP13 AGAP1 AGAP3 SOS2

3.68e-032791678PS50003
DomainGPS

ADGRG4 CELSR1 ADGRE1

3.72e-03351673PF01825
DomainPH_domain

PRKD2 DOCK11 ASAP3 CDC42BPB AKAP13 AGAP1 AGAP3 SOS2

3.76e-032801678IPR001849
DomainGPS

ADGRG4 CELSR1 ADGRE1

4.04e-03361673PS50221
DomainGBD/FH3_dom

FMNL2 DAAM1

4.15e-03111672IPR014768
DomainGBD_FH3

FMNL2 DAAM1

4.15e-03111672PS51232
DomainDHR-1_domain

DOCK1 DOCK11

4.15e-03111672IPR027007
DomainDHR_2

DOCK1 DOCK11

4.15e-03111672PS51651
DomainDHR_1

DOCK1 DOCK11

4.15e-03111672PS51650
DomainDHR-2

DOCK1 DOCK11

4.15e-03111672PF06920
DomainDOCK

DOCK1 DOCK11

4.15e-03111672IPR026791
DomainDOCK_C

DOCK1 DOCK11

4.15e-03111672IPR010703
DomainDOCK-C2

DOCK1 DOCK11

4.15e-03111672PF14429
DomainDHR-2

DOCK1 DOCK11

4.15e-03111672IPR027357
DomainGPS

ADGRG4 CELSR1 ADGRE1

4.36e-03371673IPR000203
DomainDeath_domain

ANK1 IRAK1 UNC5D

4.71e-03381673IPR000488
DomainCoatomer/clathrin_app_Ig-like

COPG2 AP2A2

4.95e-03121672IPR013041
DomainZU5

ANK1 UNC5D

4.95e-03121672PF00791
DomainZU5_dom

ANK1 UNC5D

4.95e-03121672IPR000906
DomainMIRO-like

AGAP1 AGAP3

5.81e-03131672IPR013684
DomainRoc

AGAP1 AGAP3

5.81e-03131672PF08477
Domain-

GP6 CNTN4 LRFN1 TNC MYOM3 OBSL1 PKHD1L1 HEPACAM LRFN5 PKHD1 ASTN1 ROS1 UNC5D

6.69e-03663167132.60.40.10
DomainCyt_P450_E_grp-I

CYP2C9 CYP2C18 CYP4X1

7.57e-03451673IPR002401
DomainClathrin/coatomer_adapt-like_N

COPG2 AP2A2

7.73e-03151672IPR002553
DomainFH2

FMNL2 DAAM1

7.73e-03151672PS51444
DomainFH2_Formin

FMNL2 DAAM1

7.73e-03151672IPR015425
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NCOA6 OBSL1 TNRC6B TOGARAM1 CDC42BPB TENM4 AP2A2 SYNJ1 WDR35 PCNT

2.02e-072251721012168954
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

COL6A1 NUP107 CD2AP LRRC49 RGPD1 IRAK1 TNRC6B LAMC1 COPG2 KIF15 SYNJ1 PCNT

1.30e-064181721234709266
Pubmed

Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.

STAT5A STAT5B PLCB2

2.35e-066172319647226
Pubmed

A genome-wide association study of acenocoumarol maintenance dosage.

CNTN4 CYP2C9 CYP2C18

2.35e-066172319578179
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CNTN4 CACNA1E LRFN1 DOCK11 NHSL2 RGPD1 PHB2 TNRC6B CDC42BPB ARPC2 KIF15 AP2A2 SYNJ1 KCNJ1 RABGEF1 CTNNA1 PCNT

6.51e-069631721728671696
Pubmed

NCOA6 differentially regulates the expression of the CYP2C9 and CYP3A4 genes.

NCOA6 CYP2C9 GRIP1

6.54e-068172321292004
Pubmed

The tale of the long tail: the cytoplasmic domain of HIV-1 gp41.

PHB2 AP2A2 CTNNA3 CTNNA1

7.93e-0626172423077317
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

CACNA1E TNC PHB2 KIAA1549 CDC42BPB ARPC2 GRIP1 CTNNA3 GABBR1 AGAP1 AGAP3

1.08e-054301721132581705
Pubmed

Evaluation of candidate genes for cholinesterase activity in farmworkers exposed to organophosphorus pesticides: association of single nucleotide polymorphisms in BCHE.

FMO2 CYP2C9 FMO4 CYP2C18

1.43e-0530172420529763
Pubmed

Definitive evidence using enucleated cytoplasts for a nongenomic basis for the cystic change in endoplasmic reticulum structure caused by STAT5a/b siRNAs.

STAT5A STAT5B

2.43e-052172223151802
Pubmed

Signal transducer and activator of transcription 5 (STAT5) paralog dose governs T cell effector and regulatory functions.

STAT5A STAT5B

2.43e-052172226999798
Pubmed

A Mouse Model to Assess STAT3 and STAT5A/B Combined Inhibition in Health and Disease Conditions.

STAT5A STAT5B

2.43e-052172231443474
Pubmed

Interleukin-2 family cytokines stimulate phosphorylation of the Pro-Ser-Pro motif of Stat5 transcription factors in human T cells: resistance to suppression of multiple serine kinase pathways.

STAT5A STAT5B

2.43e-052172212377952
Pubmed

A novel Ncr1-Cre mouse reveals the essential role of STAT5 for NK-cell survival and development.

STAT5A STAT5B

2.43e-052172221127177
Pubmed

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.

STAT5A STAT5B

2.43e-052172216289657
Pubmed

Inhibition of Stat5a/b Enhances Proteasomal Degradation of Androgen Receptor Liganded by Antiandrogens in Prostate Cancer.

STAT5A STAT5B

2.43e-052172225552366
Pubmed

Deletion of STAT5a/b in vascular smooth muscle abrogates the male bias in hypoxic pulmonary hypertension in mice: implications in the human disease.

STAT5A STAT5B

2.43e-052172225470773
Pubmed

Constitutively active Stat5A and Stat5B promote adipogenesis.

STAT5A STAT5B

2.43e-052172221431790
Pubmed

Stat5 Is Required for CD103+ Dendritic Cell and Alveolar Macrophage Development and Protection from Lung Injury.

STAT5A STAT5B

2.43e-052172228500076
Pubmed

STAT5 isoforms regulate colorectal cancer cell apoptosis via reduction of mitochondrial membrane potential and generation of reactive oxygen species.

STAT5A STAT5B

2.43e-052172221826656
Pubmed

Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.

STAT5A STAT5B

2.43e-05217227720707
Pubmed

STAT5A and STAT5B have opposite correlations with drug response gene expression.

STAT5A STAT5B

2.43e-052172227264955
Pubmed

Nongenomic STAT5-dependent effects on Golgi apparatus and endoplasmic reticulum structure and function.

STAT5A STAT5B

2.43e-052172222159083
Pubmed

Gene structure and upstream regulatory regions of human CYP2C9 and CYP2C18.

CYP2C9 CYP2C18

2.43e-05217228333835
Pubmed

STAT5 requires the N-domain for suppression of miR15/16, induction of bcl-2, and survival signaling in myeloproliferative disease.

STAT5A STAT5B

2.43e-052172220008792
Pubmed

STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes.

STAT5A STAT5B

2.43e-052172233199496
Pubmed

Participation of CD11b and F4/80 molecules in the conjunctival eosinophilia of experimental allergic conjunctivitis.

ITGAM ADGRE1

2.43e-052172219752566
Pubmed

The influence of STAT5 antisense oligodeoxynucleotides on the proliferation and apoptosis of selected human cutaneous T-cell lymphoma cell lines.

STAT5A STAT5B

2.43e-052172216502315
Pubmed

Stat5: an essential regulator of mast cell biology.

STAT5A STAT5B

2.43e-052172212217382
Pubmed

Brain STAT5 Modulates Long-Term Metabolic and Epigenetic Changes Induced by Pregnancy and Lactation in Female Mice.

STAT5A STAT5B

2.43e-052172231599926
Pubmed

DNA binding site selection of dimeric and tetrameric Stat5 proteins reveals a large repertoire of divergent tetrameric Stat5a binding sites.

STAT5A STAT5B

2.43e-052172210594041
Pubmed

Mitochondrial translocation of signal transducer and activator of transcription 5 (STAT5) in leukemic T cells and cytokine-stimulated cells.

STAT5A STAT5B

2.43e-052172221036145
Pubmed

Stimulation of lipolysis but not of leptin release by growth hormone is abolished in adipose tissue from Stat5a and b knockout mice.

STAT5A STAT5B

2.43e-052172210486277
Pubmed

Identification of human STAT5-dependent gene regulatory elements based on interspecies homology.

STAT5A STAT5B

2.43e-052172216840779
Pubmed

The role of the STAT5 proteins in the proliferation and apoptosis of the CML and AML cells.

STAT5A STAT5B

2.43e-052172215128421
Pubmed

STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.

STAT5A STAT5B

2.43e-052172230377054
Pubmed

Gain-of-function of Stat5 leads to excessive granulopoiesis and lethal extravasation of granulocytes to the lung.

STAT5A STAT5B

2.43e-052172223565285
Pubmed

Assessment of STAT5 as a potential therapy target in enzalutamide-resistant prostate cancer.

STAT5A STAT5B

2.43e-052172232790723
Pubmed

In vivo identification of novel STAT5 target genes.

STAT5A STAT5B

2.43e-052172218492722
Pubmed

Distinctive roles of STAT5a and STAT5b in sexual dimorphism of hepatic P450 gene expression. Impact of STAT5a gene disruption.

STAT5A STAT5B

2.43e-052172210066807
Pubmed

Molecular characterization of STAT5A- and STAT5B-encoding genes reveals extended intragenic sequence homogeneity in cattle and mouse and different degrees of divergent evolution of various domains.

STAT5A STAT5B

2.43e-052172210835485
Pubmed

Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.

STAT5A STAT5B

2.43e-052172235464049
Pubmed

Loss of cytokine-STAT5 signaling in the CNS and pituitary gland alters energy balance and leads to obesity.

STAT5A STAT5B

2.43e-052172218286195
Pubmed

Differentiating the roles of STAT5B and STAT5A in human CD4+ T cells.

STAT5A STAT5B

2.43e-052172223773921
Pubmed

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells.

STAT5A STAT5B

2.43e-05217228631883
Pubmed

Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.

STAT5A STAT5B

2.43e-052172211030348
Pubmed

Association between STAT5 polymorphisms and glioblastoma risk in Han Chinese population.

STAT5A STAT5B

2.43e-052172224878107
Pubmed

Regulation of eosinophil apoptosis by nitric oxide: Role of c-Jun-N-terminal kinase and signal transducer and activator of transcription 5.

STAT5A STAT5B

2.43e-052172212847485
Pubmed

Stat5 synergizes with T cell receptor/antigen stimulation in the development of lymphoblastic lymphoma.

STAT5A STAT5B

2.43e-052172212835478
Pubmed

Cloning and expression of Stat5 and an additional homologue (Stat5b) involved in prolactin signal transduction in mouse mammary tissue.

STAT5A STAT5B

2.43e-05217227568026
Pubmed

Identification of STAT5A and STAT5B target genes in human T cells.

STAT5A STAT5B

2.43e-052172224497979
Pubmed

Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

STAT5A STAT5B

2.43e-052172217536022
Pubmed

STAT5 transcriptional activity is impaired by LIF in a mammary epithelial cell line.

STAT5A STAT5B

2.43e-052172217382296
Pubmed

STAT5 is essential for Akt/p70S6 kinase activity during IL-2-induced lymphocyte proliferation.

STAT5A STAT5B

2.43e-052172217911616
Pubmed

STAT5 signaling in sexually dimorphic gene expression and growth patterns.

STAT5A STAT5B

2.43e-052172210486314
Pubmed

The transcription factors Stat5a/b are not required for islet development but modulate pancreatic beta-cell physiology upon aging.

STAT5A STAT5B

2.43e-052172217599554
Pubmed

MiR-21 is under control of STAT5 but is dispensable for mammary development and lactation.

STAT5A STAT5B

2.43e-052172224497923
Pubmed

Constitutive activation of STAT5A and STAT5B regulates IgM secretion in Waldenstrom's macroglobulinemia.

STAT5A STAT5B

2.43e-052172224335105
Pubmed

Brain STAT5 signaling modulates learning and memory formation.

STAT5A STAT5B

2.43e-052172229460051
Pubmed

Bif-1 Interacts with Prohibitin-2 to Regulate Mitochondrial Inner Membrane during Cell Stress and Apoptosis.

PHB2 SH3GLB1

2.43e-052172231126972
Pubmed

STAT5 deletion in macrophages alters ductal elongation and branching during mammary gland development.

STAT5A STAT5B

2.43e-052172228606561
Pubmed

Cell intrinsic defects in cytokine responsiveness of STAT5-deficient hematopoietic stem cells.

STAT5A STAT5B

2.43e-052172212393407
Pubmed

Leukocyte integrin Mac-1 recruits toll/interleukin-1 receptor superfamily signaling intermediates to modulate NF-kappaB activity.

IRAK1 ITGAM

2.43e-052172211701612
Pubmed

The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoter.

STAT5A STAT5B

2.43e-052172212039059
Pubmed

Differential changes in responses of hypothalamic and brainstem neuronal populations to prolactin during lactation in the mouse.

STAT5A STAT5B

2.43e-052172221178171
Pubmed

DRAKs, novel serine/threonine kinases related to death-associated protein kinase that trigger apoptosis.

STK17B STK17A

2.43e-05217229786912
Pubmed

Stat5 promotes metastatic behavior of human prostate cancer cells in vitro and in vivo.

STAT5A STAT5B

2.43e-052172220233708
Pubmed

Involvement of the STAT5 signaling pathway in the regulation of mouse preimplantation development.

STAT5A STAT5B

2.43e-052172216775227
Pubmed

STAT5 isoforms: controversies and clarifications.

STAT5A STAT5B

2.43e-052172217447893
Pubmed

Uterine leiomyoma with RAD51B::NUDT3 fusion: a report of 2 cases.

RAD51B NUDT3

2.43e-052172237466765
Pubmed

αE-catenin is an autoinhibited molecule that coactivates vinculin.

CTNNA3 CTNNA1

2.43e-052172222586082
Pubmed

Generation and characterization of novel cytochrome P450 Cyp2c gene cluster knockout and CYP2C9 humanized mouse lines.

CYP2C9 CYP2C18

2.43e-052172222918969
Pubmed

Activation of signal transducer and activator of transcription-5 in prostate cancer predicts early recurrence.

STAT5A STAT5B

2.43e-052172216115927
Pubmed

Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.

STAT5A STAT5B

2.43e-052172223275557
Pubmed

Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced STAT5 activation and target-gene expression during human monocyte/macrophage differentiation.

STAT5A STAT5B

2.43e-052172211867689
Pubmed

Global analysis of IL-2 target genes: identification of chromosomal clusters of expressed genes.

STAT5A STAT5B

2.43e-052172215980098
Pubmed

Presynaptic Excitation via GABAB Receptors in Habenula Cholinergic Neurons Regulates Fear Memory Expression.

CACNA1E GABBR1

2.43e-052172227426949
Pubmed

Inactivation of Stat5 in mouse mammary epithelium during pregnancy reveals distinct functions in cell proliferation, survival, and differentiation.

STAT5A STAT5B

2.43e-052172215340066
Pubmed

STAT5A/B gene locus undergoes amplification during human prostate cancer progression.

STAT5A STAT5B

2.43e-052172223660011
Pubmed

Role of Stat5 in type I interferon-signaling and transcriptional regulation.

STAT5A STAT5B

2.43e-052172212901872
Pubmed

O-GlcNAcylation of STAT5 controls tyrosine phosphorylation and oncogenic transcription in STAT5-dependent malignancies.

STAT5A STAT5B

2.43e-052172228074064
Pubmed

STAT5b: A master regulator of key biological pathways.

STAT5A STAT5B

2.43e-052172236755813
Pubmed

Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling.

STAT5A STAT5B

2.43e-052172225333863
Pubmed

A role for STAT5 in the pathogenesis of IL-2-induced glucocorticoid resistance.

STAT5A STAT5B

2.43e-052172212421978
Pubmed

A single amino acid in the DNA binding regions of STAT5A and STAT5B confers distinct DNA binding specificities.

STAT5A STAT5B

2.43e-05217229852045
Pubmed

Signal transducer and activator of transcription (STAT)-5A and STAT5B differentially regulate human mammary carcinoma cell behavior.

STAT5A STAT5B

2.43e-052172219966185
Pubmed

Signal transducer and activator of transcription 5a/b: biomarker and therapeutic target in prostate and breast cancer.

STAT5A STAT5B

2.43e-052172221704724
Pubmed

Hyperactive STAT5 hijacks T cell receptor signaling and drives immature T cell acute lymphoblastic leukemia.

STAT5A STAT5B

2.43e-052172238618957
Pubmed

Characterization and cloning of STAT5 from IM-9 cells and its activation by growth hormone.

STAT5A STAT5B

2.43e-05217228732682
Pubmed

How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5.

STAT5A STAT5B

2.43e-052172226717567
Pubmed

The neonatal microenvironment programs innate γδ T cells through the transcription factor STAT5.

STAT5A STAT5B

2.43e-052172232281944
Pubmed

Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice.

STAT5A STAT5B

2.43e-052172234818373
Pubmed

Interference of propofol with signal transducer and activator of transcription 5 activation and cardioprotection by remote ischemic preconditioning during coronary artery bypass grafting.

STAT5A STAT5B

2.43e-052172223465551
Pubmed

STAT5 promotes multilineage hematolymphoid development in vivo through effects on early hematopoietic progenitor cells.

STAT5A STAT5B

2.43e-052172211756158
Pubmed

Regulation of IL-1 receptor-associated kinases by lipopolysaccharide.

IRAK1 PRKCZ

2.43e-052172211937546
Pubmed

IL-3 Differentially Regulates Membrane and Soluble RANKL in Osteoblasts through Metalloproteases and the JAK2/STAT5 Pathway and Improves the RANKL/OPG Ratio in Adult Mice.

STAT5A STAT5B

2.43e-052172229203513
Pubmed

Prognostic significance of signal transducer and activator of transcription 5 and 5b expression in Epstein-Barr virus-positive patients with chronic lymphocytic leukemia.

STAT5A STAT5B

2.43e-052172227367207
Pubmed

Clarifying the role of Stat5 in lymphoid development and Abelson-induced transformation.

STAT5A STAT5B

2.43e-052172216493008
Pubmed

Deletion of the carboxyl-terminal transactivation domain of MGF-Stat5 results in sustained DNA binding and a dominant negative phenotype.

STAT5A STAT5B

2.43e-05217228816482
Pubmed

The role of STAT proteins in growth hormone signaling.

STAT5A STAT5B

2.43e-052172210851057
Cytoband1q24.3

MROH9 FMO2 FMO4

5.62e-052017231q24.3
Cytoband11p14.2

SLC5A12 BBOX1

2.89e-047172211p14.2
CytobandEnsembl 112 genes in cytogenetic band chr14q21

MIS18BP1 TOGARAM1 LRFN5 SOS2

5.03e-04971724chr14q21
GeneFamilyFibronectin type III domain containing

CNTN4 LRFN1 TNC MYOM3 LRFN5 ASTN1 ROS1

7.34e-051601157555
GeneFamilyX-linked mental retardation|Rho GTPase activating proteins|BAR-PH domain containing

ASAP3 AGAP1 AGAP3

1.60e-041711531291
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

PRKD2 DOCK11 ASAP3 AKAP13 AGAP1 AGAP3 SOS2

3.49e-042061157682
GeneFamilyAnkyrin repeat domain containing|Death associated protein kinases

STK17B STK17A

3.96e-04511521021
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CNTN4 LRFN1 MYOM3 OBSL1 LRFN5 UNC5D

5.75e-041611156593
GeneFamilyArfGAPs

ASAP3 AGAP1 AGAP3

1.19e-03331153395
GeneFamilyCopines

CPNE8 CPNE9

1.40e-0391152829
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D9B TBC1D9

2.99e-031311521146
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CNTN4 CACNA1E FBLL1 ANK1 PCLO LRRC49 KIAA1549 GRID2 XK FMNL2 TBC1D9 GRIP1 FSIP2 SYNJ1 LRFN5 RABGAP1L CYP4X1 PRKCZ DAAM1 CCDC144A AGAP1

1.27e-05110617221M39071
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

PPP1R21 CNTN4 PCLO TNRC6B RABGAP1L PKHD1 AKAP13 SLC5A12 AGAP1

1.64e-052211729M39222
CoexpressionLAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM

PPP1R21 CNTN4 SLC26A3 ANK1 KIAA1549 TNRC6B ADAMTS8 TENM4 CTNNA3 PIP5K1A AKAP13 SLC5A12

2.15e-0541717212M39224
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 RAD51B SLC26A3 TNRC6B EXT1 FMNL2 WDPCP GRIP1 RABGAP1L AGAP1

5.87e-091991721094b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ATP13A4 PGGHG DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

3.78e-081811729071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ATP13A4 PGGHG DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

4.15e-081831729738e94b50c4c08c727d4eed0708dda08aa6891b4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 ANK1 ABCA13 PCLO PKHD1L1 TENM4 PKHD1 ROS1 UNC5D

4.35e-0818417292cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 ANK1 ABCA13 PCLO PKHD1L1 TENM4 PKHD1 ROS1 UNC5D

4.35e-081841729ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP13A4 ANK1 ABCA13 PCLO PKHD1L1 TENM4 PKHD1 ROS1 UNC5D

4.35e-0818417292b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SEMA6B PCLO TENM4 DACH2 PKHD1 ASTN1 RORB DNAH8 UNC5D

4.78e-08186172923b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

ZNF460 EID2 RANBP6 HDHD2 GRIP1 KIF15 PIP5K1A CCDC144A

3.06e-0716817288697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ATP13A4 DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

4.56e-071771728da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellEpithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|World / Lineage, Cell type, age group and donor

CNTN4 ATP13A4 GRIP1 CELSR1 ROS1 ATP6V1C2 PRKCZ AGAP1

6.91e-07187172881cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 PCLO GRIP1 CELSR1 ATP2C2 CTNNA3 PKHD1 PRKCZ

7.19e-0718817280d86044bc340e3efb90d0022dd299873639d831c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ATP13A4 DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

7.19e-07188172863a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 PCLO GRIP1 CELSR1 ATP2C2 CTNNA3 PKHD1 PRKCZ

7.19e-071881728beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 PCLO GRIP1 CELSR1 ATP2C2 CTNNA3 PKHD1 PRKCZ

7.48e-0718917287659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 OR2G6 MYOM3 KIAA1549 FAM135B PKHD1 UNC5D AGAP1

7.79e-071901728989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TNRC6B EXT1 BABAM2 RABGAP1L PKHD1 AKAP13 SLC5A12 AGAP1

8.43e-071921728e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAD51B CNTN4 ATP13A4 FMO2 GRIP1 CELSR1 GNA14 AGAP1

1.06e-061981728af399569c718f5fd971d73a7926768c9311002a3
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAD51B CNTN4 ATP13A4 FMO2 GRIP1 CELSR1 GNA14 AGAP1

1.06e-0619817281408e02e053ad3406229bfe8189da03be6366e81
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PGGHG ABCA13 COL28A1 PCLO ATP2C2 CCDC78 CYP4X1

2.55e-06156172710d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

ATP13A4 OBSL1 AKAP13 ROS1 ATP6V1C2 PRKCZ AGAP1

2.66e-06157172731d1bd9138c60e8485664ec4144f987226e3eef9
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC26A3 ABCA13 TECTA PKHD1L1 PKHD1 ROS1 UNC5D

3.27e-061621727bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 ATP13A4 DOCK11 ABCA13 PARP4 PKHD1 UNC5D

5.65e-061761727327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 CPNE9 SLC6A7 RORB ROS1 TMEM26 UNC5D

5.86e-061771727f902600c639087664316b3cf30cab243bc3d1c5c
ToppCellAdult-Epithelial-club_cell-D175|Adult / Lineage, Cell type, age group and donor

CNTN4 FMO2 PGGHG GRIP1 CELSR1 GNA14 AGAP1

5.86e-061771727d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 CACNA1E PCLO KIAA1549 PKHD1 SLC5A12 BBOX1

6.08e-06178172723a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

RAD51B FMO2 GRIP1 CELSR1 GNA14 ATP6V1C2 AGAP1

6.08e-06178172735a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

COL6A1 CPNE9 SLC6A7 RORB ROS1 TMEM26 UNC5D

6.31e-0617917278766a5a066091879f521acfc612abf563ff78808
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 PCLO GRIP1 PKHD1 SLC5A12 BBOX1 UNC5D

6.54e-061801727358923e4228035a3e90e2957392089219e90dcd7
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 CACNA1E GRIP1 PKHD1 SLC5A12 BBOX1 UNC5D

6.54e-061801727864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

RAD51B CNTN4 ATP13A4 GRIP1 GNA14 ROS1 AGAP1

6.78e-061811727c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

7.29e-06183172792fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

CNTN4 DOCK11 ABCA13 MYOM3 KIAA1549 GRIP1 PKHD1

7.55e-06184172751ed1ebfdef45149541917c66cbacad87072e51f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP5 DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

7.55e-061841727da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO2 F2RL1 GRIP1 CELSR1 PKHD1 PRKCZ

7.82e-0618517273bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 FMNL2 FAM135B GRIP1 PKHD1 UNC5D AGAP1

8.10e-061861727b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ATP13A4 GRIP1 ATP2C2 CTNNA3 PKHD1 ROS1 PRKCZ

8.39e-061871727db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

COL6A1 NHSL2 TNC CDH23 LAMC1 ADAMTS8 LRFN5

8.39e-061871727e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 KIAA1549 CELSR1 PKHD1 UNC5D AGAP1

8.39e-0618717279d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 PARP4 CELSR1 PKHD1 UNC5D

8.99e-061891727904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 MYOM3 FAM135B GRIP1 PKHD1 SLC5A12 UNC5D

8.99e-06189172728b502611829e4a24caff2562545c7db97686099
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAD51B ATP13A4 FMO2 GRIP1 CELSR1 GNA14 AGAP1

9.63e-06191172723776c7302cead3881b39127398f3b3e0d27885e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 FAM135B GRIP1 PKHD1 UNC5D AGAP1

9.63e-0619117271cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

DOCK1 COL6A1 TNC LAMC1 EXT1 TENM4 AGAP1

9.96e-06192172760b1312e84f6d6448365a952469c506c00b5fe93
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AKAP5 PGGHG DOCK11 ABCA13 PARP4 PKHD1 UNC5D

1.03e-051931727ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

RAD51B CNTN4 ATP13A4 FMO2 GRIP1 CELSR1 AGAP1

1.03e-0519317272bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL6A1 FMO2 NHSL2 CDH23 LAMC1 EXT1 ADAMTS8

1.03e-051931727b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

COL6A1 FMO2 NHSL2 TNC LAMC1 ADAMTS8 LRFN5

1.03e-051931727acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ATP13A4 CELSR1 ATP2C2 CTNNA3 PKHD1 ROS1 PRKCZ

1.03e-051931727a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PCLO GRIP1 CELSR1 ATP2C2 CTNNA3 PKHD1 PRKCZ

1.07e-051941727f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

RAD51B ATP13A4 FMO2 COL28A1 GRIP1 CELSR1 AGAP1

1.10e-051951727dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CYP2C9 ABCA13 GRIP1 CELSR1 TENM4 GNA14 ATP2C2

1.10e-051951727e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 RAD51B ATP13A4 SLC26A3 EXT1 RABGAP1L AGAP1

1.14e-051961727ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

MROH9 MIS18BP1 FMO4 CPNE9 CDH23 TBC1D9 GTF3A

1.22e-051981727d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 RAD51B ATP13A4 SLC26A3 EXT1 RABGAP1L AGAP1

1.22e-0519817271996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RAD51B CNTN4 ATP13A4 FMO2 PCLO GRIP1 CELSR1

1.22e-0519817276ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV-2|World / Primary Cells by Cluster

CNTN4 CACNA1E CPNE8 PCLO NUDT3 DAAM1 CCDC144A

1.26e-051991727f09b40245d3d826275bbe5f508dedccc75a911bd
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_IV|World / Primary Cells by Cluster

CNTN4 CACNA1E CPNE8 PCLO NUDT3 DAAM1 CCDC144A

1.26e-051991727e45448ec4db8875c8aaa9aad109a10e2905a4226
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 PARP4 PKHD1 UNC5D

1.55e-0513717260aa4e14b32da0cda677cc0ed6ae470f6ecd77bea
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

PGGHG BABAM2 STAT5B CELSR1 ADGRE1 ARHGAP45

2.80e-0515217262ff0980dfd8d430cca14649151d856edef115720
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 PARP4 PKHD1 UNC5D

2.90e-051531726d6526d17826470534b766df144c74e73eb83fdad
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 TECTA PKHD1L1 GRIP1 PKHD1 ASTN1

3.73e-051601726c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 ANK1 SLC6A7 LRFN5 ATP2C2 PKHD1

3.73e-05160172641d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 ANK1 SLC6A7 LRFN5 ATP2C2 PKHD1

3.73e-051601726c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 TECTA PKHD1L1 GRIP1 PKHD1 ASTN1

3.73e-05160172625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE8 AKAP5 CPNE9 TENM4 RORB UNC5D

4.13e-0516317261e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CPNE8 AKAP5 CPNE9 TENM4 RORB UNC5D

4.13e-051631726431221a41d396b09170476179590eaf8a55266d8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PGGHG DOCK11 ABCA13 FSIP2 PARP4 PKHD1

5.23e-0517017265d5f208682be21ed58320f5fc083a7898f8712da
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

RAD51B HYKK ABCA13 GRIP1 CELSR1 DACH2

5.40e-0517117263965ced4be6db14265a90673502fceee425837ca
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MIS18BP1 NUP107 RRM1 ZBTB14 OR10A4 ZNF382

5.76e-0517317269f892d756d05e573af018db64edb130ff187ad47
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

GP6 ANK1 OR2B2 PKHD1L1 SLC8A3 ARHGAP45

6.14e-0517517264c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 ABCA13 ITGAM FMNL2 TMEM26 AGAP1

6.14e-051751726cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell356C-Lymphocytic-NK_cells-NK_cell_A2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ANK1 OBSL1 KIAA1549 XK TBC1D9 GABBR1

6.33e-051761726052b54c4337ca728974a106b6dbd3b72dd28eb23
ToppCellFetal_29-31_weeks-Epithelial-club_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTN4 ATP13A4 GRIP1 CELSR1 GNA14 AGAP1

6.33e-0517617263bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)-|368C / Donor, Lineage, Cell class and subclass (all cells)

PCLO F2RL1 CYP4X1 RORB ROS1 WDR90

6.54e-051771726ac8f774596068e66c0a9ea8a318be0ce5f5df834
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EPN3 COL6A1 TBC1D9 KCNJ1 PKHD1 KNG1

6.54e-051771726c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell368C-Epithelial_cells-Epithelial-B_(AT2)|368C / Donor, Lineage, Cell class and subclass (all cells)

PCLO F2RL1 CYP4X1 RORB ROS1 WDR90

6.54e-051771726d9c4a93b0e04a13bf39992dd1c1ec8df2c5f89fe
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO2 GRIP1 CELSR1 PKHD1 PRKCZ

6.54e-0517717269af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 PARP4 PKHD1 UNC5D

6.74e-051781726c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 ATP13A4 GRIP1 ATP6V1C2 PRKCZ AGAP1

6.74e-051781726f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TNC OPN3 FMNL2 SLC6A7 TENM4 UNC5D

6.74e-051781726a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTN4 ATP13A4 CELSR1 ATP2C2 CTNNA3 ROS1

6.95e-051791726815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 OR2G6 MYOM3 UNC5D

6.95e-05179172658ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIS18BP1 TOGARAM1 SLC7A6 TENM4 KIF15 KNG1

6.95e-0517917264166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO2 GRIP1 CELSR1 PKHD1 PRKCZ

6.95e-05179172604ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 MYOM3 KIAA1549 FAM135B SLC5A12 UNC5D

7.39e-0518117269542c19edc9bd2cba68c01c2a8407705398e3011
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO2 GRIP1 CELSR1 PKHD1 PRKCZ

7.39e-051811726b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 MYOM3 KIAA1549 FAM135B SLC5A12 UNC5D

7.39e-0518117268f04f8cac5d705dc5f6cf6f4516d6e45b0aa4ae5
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 CACNA1E PCLO PKHD1 SLC5A12 BBOX1

7.39e-0518117266980ea624151da32b7f537f263e40fcb87a02e81
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PPP1R21 SLC6A7 GNA14 LRFN5 RORB UNC5D

7.39e-05181172657994ff4ecffb15653aee00644d9f887f5e3461d
ToppCellPosterior_cortex-Macroglia-ASTROCYTE-Gja1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP13A4 TNC MYOM3 CELSR1 BBOX1

7.43e-051121725e30cd0b7b755c63081bbeed4e1a884b6640d34f8
ToppCellPosterior_cortex-Macroglia-ASTROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ATP13A4 TNC MYOM3 CELSR1 BBOX1

7.43e-0511217251c0bcc6c972c50a9d950cd56b65efb8d778ec25a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CNTN4 DOCK11 ABCA13 PARP4 PKHD1 UNC5D

7.62e-0518217265e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 PCLO GRIP1 PKHD1 SLC5A12 BBOX1

7.62e-0518217269d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CNTN4 ABCA13 KIAA1549 GRIP1 PKHD1 BBOX1

7.86e-0518317266878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO2 GRIP1 CELSR1 PKHD1 PRKCZ

7.86e-051831726ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ATP13A4 FMO2 CD2AP CELSR1 PKHD1 PRKCZ

8.10e-05184172642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L4-5_PVALB_TRIM67|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK1 DOCK11 GRIP1 KCNJ5 PKHD1 PCNT

8.10e-0518417267f6c8912677764d438ab0555faca344d74c2f483
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 ATP13A4 COL28A1 GRIP1 ATP6V1C2 AGAP1

8.10e-051841726102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

CNTN4 ATP13A4 GRIP1 CELSR1 ROS1 AGAP1

8.34e-051851726cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E PCLO PKHD1 SLC5A12 BBOX1 UNC5D

8.34e-0518517261bbc2ba8a20f72f61981b1301cdd6018cdd9150d
Diseasecortical thickness

RAD51B STK17B LRRC49 TNRC6B LAMC1 EXT1 ADAMTS8 TSC22D2 FMNL2 ARPC2 GRIP1 CELSR1 GNA13 PKHD1 PRKCZ USP35 AGAP1 AGAP3 SOS2

1.91e-05111316719EFO_0004840
Diseaseintraocular pressure measurement

RAD51B MROH9 COL6A1 PCLO ADAMTS8 TSC22D2 FMNL2 BABAM2 PKHD1 AKAP13 TMEM26 SOS2

3.57e-0550916712EFO_0004695
DiseaseX-21258 measurement

CYP2C9 CYP2C18

9.52e-0531672EFO_0800802
Diseasediet measurement, body mass index

DOCK1 ATP13A4 GRID2

1.89e-04201673EFO_0004340, EFO_0008111
Diseasenephrotic syndrome type 20 (implicated_via_orthology)

TBC1D9B TBC1D9

1.90e-0441672DOID:0070357 (implicated_via_orthology)
Diseaseprogranulin measurement

CDH23 GRIP1 LRFN5

2.53e-04221673EFO_0004625
Diseaseneuroimaging measurement

RAD51B STK17B LRRC49 RGPD1 TNRC6B LAMC1 EXT1 TSC22D2 CELSR1 SYNJ1 GNA13 PKHD1 PRKCZ GABBR1 AGAP1 AGAP3

3.95e-04106916716EFO_0004346
DiseaseCiliopathies

CDH23 WDPCP PKHD1 WDR35 DNAH8

4.15e-041101675C4277690
DiseaseSubstance abuse problem

DOCK1 RAD51B CTNNA3 ASTN1 DNAH8

5.29e-041161675C0740858
Diseasecortical surface area measurement

RAD51B PRKD2 STK17B RGPD1 TNRC6B LAMC1 EXT1 TSC22D2 FMNL2 GRIP1 CELSR1 PKHD1 PRKCZ USP35 DAAM1 AGAP1 AGAP3 SOS2

6.43e-04134516718EFO_0010736
Diseaseglycine conjugate of C10H14O2 (1) measurement

CYP2C9 CYP2C18

6.56e-0471672EFO_0800655
Diseaseinvasive lobular carcinoma (is_marker_for)

STAT5A CTNNA1

6.56e-0471672DOID:3457 (is_marker_for)
Diseasealcohol consumption measurement

DOCK1 CACNA1E CPNE8 PCLO GCKR FMNL2 BABAM2 WDPCP FAM135B GRIP1 LRFN5 RABGAP1L ASB3 PKHD1 SMU1 WDR90 CTNNA1

7.12e-04124216717EFO_0007878
Diseasepneumococcal meningitis

CELSR1 ROS1

8.72e-0481672EFO_1001114
Diseaseresponse to alcohol

FAM135B ASB3 PKHD1 MAN1B1

8.80e-04751674EFO_0005526
DiseaseDisproportionate short stature

OBSL1 EXT1 WDR35 PCNT

9.71e-04771674C0878659
Diseaseserum metabolite measurement

MROH9 CNTN4 CACNA1E CYP2C9 CYP2C18 GPAA1 HYKK GCKR SLC7A6 ITGAM PARP4 RABGAP1L TXNDC16 BBOX1

1.01e-0394516714EFO_0005653
Diseasecognitive function measurement

RAD51B CNTN4 CACNA1E COPG2 GRID2 EXT1 TSC22D2 SLC7A6 WDPCP FAM135B TENM4 GUCA1A RABGAP1L ASB3 CTNNA3 PKHD1 AGAP1 REV1

1.33e-03143416718EFO_0008354
Diseasemetabolite measurement

MROH9 FMO2 CYP2C9 FMO4 GPAA1 GCKR SLC7A6 BABAM2 BBOX1 KNG1

1.39e-0356016710EFO_0004725
Diseasegamma-glutamylthreonine measurement

GCKR ADGRE1

1.39e-03101672EFO_0021143
Diseaseresponse to bronchodilator, FEV/FEC ratio

CNTN4 HYKK GRID2 GCKR F2RL1 FAM135B GRIP1 TENM4 ASB3 PKHD1 UNC5D AGAP1

1.45e-0376616712EFO_0004713, GO_0097366
DiseaseMoyamoya disease

DOCK1 TSC22D2 FMNL2

1.51e-03401673MONDO_0016820
Diseasecardiac troponin T measurement

CDH23 CELSR1 CTNNA3 PKHD1 ATP6V1C2 TMEM26

1.59e-032191676EFO_0005043
DiseaseUterine leiomyoma

NUP107 TNRC6B BABAM2 REV1

1.80e-03911674HP_0000131
Diseaseliver fat measurement

GCKR PRKCZ LMBRD1

1.86e-03431673EFO_0010821
Diseasetriacylglycerol 56:6 measurement

GCKR DACH2 ATP2C2

1.86e-03431673EFO_0010433
DiseaseRS-6-hydroxywarfarin measurement

CNTN4 ATP13A4 GRID2 XK GNA14

1.93e-031551675EFO_0803328
DiseaseAlzheimer disease, polygenic risk score

RAB23 CACNA1E OR2B2 CD2AP WDPCP FSIP2 CTNNA3 PKHD1 CTNNA1 GABBR1

1.94e-0358616710EFO_0030082, MONDO_0004975
Diseaseunipolar depression, bipolar disorder

CACNA1E ATP13A4 PCLO TENM4 LRFN5

1.99e-031561675EFO_0003761, MONDO_0004985
DiseaseMethionine sulfoxide measurement

FMO2 FMO4

2.02e-03121672EFO_0021650
Diseaseniacinamide measurement

FMO2 FMO4

2.02e-03121672EFO_0010511
Diseasesystemic lupus erythematosus

RAD51B RAB23 MROH9 DEAF1 IRAK1 CDH23 LAMC1 ITGAM RABGAP1L CTNNA3 CCDC116 GABBR1

2.06e-0379916712MONDO_0007915
Diseasebrain connectivity measurement

RAD51B CNTN4 HYKK ADAMTS8 TSC22D2 TENM4 DACH2 DAAM1

2.08e-034001678EFO_0005210
Diseasebrain volume measurement

PPP1R21 PRKD2 TBC1D9B STK17A LRRC49 ADAMTS8 CCDC144CP PKHD1 PRKCZ DAAM1

2.16e-0359516710EFO_0006930
Diseasemajor depressive episode

MROH9 ATP13A4 TENM4

2.40e-03471673EFO_0007634
Diseasecaudate nucleus measurement, functional brain measurement, response to reward

XK FAM135B CELSR1

2.40e-03471673EFO_0007849, EFO_0008387, EFO_0008396
Diseaseserum IgG glycosylation measurement

CACNA1E CPNE8 SLC26A3 TSC22D2 FMNL2 DHX8 SLC8A3 GNA14 SOS2

3.06e-035231679EFO_0005193
Diseasemonoclonal gammopathy

RAD51B CNTN4 TNC

3.39e-03531673EFO_0000203
Disease5-oxoproline measurement

GPAA1 DNAH8

3.63e-03161672EFO_0010988
Diseaseunipolar depression

CACNA1E ABCA13 TNC STK17B PCLO EXT1 CDC42BPB WDPCP FAM135B LRFN5 CTNNA3 PKHD1 ASTN1 DAAM1 GABBR1

3.65e-03120616715EFO_0003761
Diseaselymphocyte count

RAD51B CYP2C9 ANK1 OPN3 IRAK1 CDH23 TNRC6B GCKR RRM1 FMNL2 STAT5B TENM4 NUDT3 ASB3 ADGRE1 ARHGAP45 AGAP1

4.01e-03146416717EFO_0004587
Diseasemean corpuscular hemoglobin concentration

RAD51B PPP1R21 GPAA1 ANK1 STK17A PHB2 TNRC6B GCKR RRM1 GNA14 ASB3 PIP5K1A AKAP13 AGAP1

4.20e-03110516714EFO_0004528
DiseaseDrug habituation

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0013170
DiseaseDrug abuse

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0013146
DiseasePrescription Drug Abuse

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C4316881
DiseaseSubstance-Related Disorders

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0236969
DiseaseDrug Use Disorders

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0013222
DiseaseDrug Dependence

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C1510472
DiseaseSubstance Dependence

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0038580
DiseaseSubstance Use Disorders

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

DOCK1 RAD51B CTNNA3 DNAH8

4.20e-031151674C0029231
Diseaseinsulin measurement

CNTN4 CACNA1E GCKR TSC22D2 NUDT3 LRFN5

4.25e-032671676EFO_0004467
DiseaseC-X-C motif chemokine 16 measurement

LZTFL1 CDH23

4.59e-03181672EFO_0010911
Diseasemetabolonic lactone sulfate measurement

CYP2C9 CYP2C18

5.11e-03191672EFO_0800659
DiseaseHypertriglyceridemia

LAMC1 GCKR

5.11e-03191672EFO_0004211
Diseasecytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant

PCLO CDH23

5.11e-03191672EFO_0007044, EFO_0020106
DiseaseUlcerative Colitis

SLC26A3 ARPC2 MASP2

5.51e-03631673C0009324
Diseasecorneal hysteresis

COL6A1 ADAMTS8

5.66e-03201672EFO_0010066

Protein segments in the cluster

PeptideGeneStartEntry
VFVFSLEDEISFQTV

AGAP3

161

Q96P47
SSATEEAEESFEFVV

AGAP3

561

Q96P47
TSAVATLTDSDEKFI

CABS1

251

Q96KC9
TLTDSDEKFITVFEL

CABS1

256

Q96KC9
DEKFITVFELTTSAE

CABS1

261

Q96KC9
SVAEFLAVTAEDLSS

ASAP3

6

Q8TDY4
FLTESQVLDSLETVV

CCDC116

76

Q8IYX3
IFVFSLEDEISFQTV

AGAP1

141

Q9UPQ3
EEETLTFEAAVATSL

CACNA1E

2246

Q15878
LVDETATFAVDVLST

ADGRG4

306

Q8IZF6
DLEETTTLASFISEV

APOF

286

Q13790
ATTLTRETVESDLIF

ATP13A4

671

Q4VNC1
SEARFVETLLVADAS

ADAMTS8

216

Q9UP79
SVTDVLKVVTDETSF

ANK1

781

P16157
LKVVTDETSFVLVSD

ANK1

786

P16157
VTVVFSTVFKDDDDV

ARPC2

161

O15144
ETAETFDAVVASEVV

COQ3

211

Q9NZJ6
SEIADLTFNTVAFTE

EPN3

41

Q9H201
EVDFRASSISEEVAV

AKAP13

1356

Q12802
ASIFARSLSATDIEV

CNTN4

806

Q8IWV2
FSDILEEIAEFLTSV

ABCA13

2631

Q86UQ4
EEDASEISVSVVFET

CCDC144CP

296

Q8IYA2
VAAVLSTTKDDVFVF

CELSR1

1231

Q9NYQ6
FDSLTVRTSKETDVV

CD2AP

461

Q9Y5K6
FIFADSLSSVETLLT

DACH2

446

Q96NX9
SLETLTAAEATAFER

CDH23

3311

Q9H251
LTEVTDLLVDESSFT

ATP2C2

206

O75185
VETETVLSFVDDIIS

ASTN1

1081

O14525
STVASTDILATVLEE

AP2A2

586

O94973
IDTESAFSAERLVEI

RAD51B

141

O15315
VLVFSTTDRESFEAV

RAB23

86

Q9ULC3
TSIETDRVSKEFIEF

RABGEF1

131

Q9UJ41
QSALEEESVFAVTAV

NUP107

231

P57740
FVSAFLFSIETETTI

KCNJ5

136

P48544
LVETFTLFDSSDLQS

KIAA1549

666

Q9HCM3
TLISSTAFDDVFALE

LRFN5

136

Q96NI6
ALTALVTVSSEEFED

C8orf76

341

Q96K31
EIDDESASFTVTVTE

OBSL1

971

O75147
ALETIAVAFSSTVSE

ARHGAP45

206

Q92619
ESRLVEDTFTIDEVS

LZTFL1

41

Q9NQ48
VSIDILTSREQFFSD

MIS18BP1

621

Q6P0N0
ADVDTTQESVFATVA

KIF15

76

Q9NS87
ELSSDVVTSLDVAVE

GPAA1

226

O43292
TEVFTSTLDDLEERV

GABBR1

316

Q9UBS5
EFVEKTLSTIATSTD

HADH

91

Q16836
DISEDEIFTSLTAAR

HDHD2

66

Q9H0R4
ESEVVSTITAIFSLA

LMBRD1

41

Q9NUN5
RVESAAFDAFLSTVE

LRFN1

151

Q9P244
ATETILSQELTDFTF

FSIP2

2316

Q5CZC0
FIVNSSVFLEEVISE

FSIP2

4941

Q5CZC0
SIVLEFTTSEILVAD

FSIP2

4991

Q5CZC0
AEFSEATAELTVSFT

GP6

221

Q9HCN6
ATAELTVSFTNEVFT

GP6

226

Q9HCN6
SFITEVVETNLVAFD

GRID2

241

O43424
IDSTASAEAVFASEV

FBLL1

281

A6NHQ2
FDAVTTLETTAVLRS

PCLO

2456

Q9Y6V0
FRSESEEEVLLVSSS

NUDT3

26

O95989
SSLTLESFFQEVELV

DNAH8

686

Q96JB1
SVIEFTETSAVFEDG

FMO4

301

P31512
VEVVLSASATFEDFQ

PRKD2

121

Q9BZL6
ITTVSFTFIEFDEIV

LRRC49

441

Q8IUZ0
TTTAVISKDFTEDRI

MVD

51

P53602
VIFTLDDTVAEFVAA

MVD

311

P53602
FTLTISILQSEDFAV

IGKV3D-15

91

A0A087WSY6
FSFSEDSVTVEVTAR

PGGHG

636

Q32M88
TSILFLVSSSEFDQV

GNA13

241

Q14344
DDEFSVSSVLASDVI

CDC42BPB

1151

Q9Y5S2
TASVTTDFEDDEFVV

PARP4

536

Q9UKK3
LFESITEDTVTVLET

PPP1R21

321

Q6ZMI0
LAVDTDTFSFGVVVL

IRAK1

401

P51617
EDTVIVLIFLTEVSF

MROH9

521

Q5TGP6
SLILDDVAITELSFS

PHB2

176

Q99623
VEDFITTSFDSQETL

PCNT

2311

O95613
TSTTLEKLEVAESEF

PIP5K1A

546

Q99755
SDSTVAEVTSIQLEF

MAN1B1

391

Q9UKM7
SDVFTFSVSLEVKED

RABGAP1L

271

Q5R372
EFVLVSFSALSTELQ

OR10A4

11

Q9H209
ADTSVFELEALTATV

OR10A4

191

Q9H209
CSAVSDFDFIVTIVV

THAP12

471

O43422
EVNTTFEDFVAIISS

PRPF40A

691

O75400
TEIDTVVFIFTLDDN

GCKR

401

Q14397
DTKSDSILEDSTIFV

NCOA6

36

Q14686
ETVFSVDEFSASVLT

F2RL1

56

P55085
IIFIITSDESLSVDD

OPN3

371

Q9H1Y3
AVDDITSIDDFLAVS

CTNNA3

496

Q9UI47
FITVASFSFSDVEDL

DAAM1

931

Q9Y4D1
SDTISDALLTDSFII

WDPCP

161

O95876
SFVTDIFERIASEAS

H2BC1

66

Q96A08
SVSIDTLIFTLEFTN

ASB3

416

Q9Y575
TFSEEQASALVESVF

HYKK

16

A2RU49
FIDIVFIVDSSESSK

COL28A1

46

Q2UY09
ATEVSLTVLDTISFF

DOCK11

1401

Q5JSL3
SESETFDTLVFDALV

DOCK1

666

Q14185
AVDDITSIDDFLAVS

CTNNA1

501

P35221
EDTVLSTTEVDFAFT

EXT1

566

Q16394
ALLSVSFEDTEATQV

BABAM2

201

Q9NXR7
VDLFFVLDTSESVAL

COL6A1

36

P12109
ALTFDRASTVEATAV

DEAF1

346

O75398
TLLSFSVDSEFTFVD

CPNE9

276

Q8IYJ1
FSDIDVHSEVSTFLL

CYP4X1

301

Q8N118
ILSSTFVDFTDIGVD

BBOX1

251

O75936
EEDASEISVSVVFET

CCDC144B

346

Q3MJ40
IITDTEISEFDVTKS

AKAP5

341

P24588
ATTALRTFLEATLED

CCDC78

266

A2IDD5
SFVSEISDEFKVVVV

COPG2

366

Q9UBF2
AVTFDFESVESTVES

FMNL2

146

Q96PY5
DILTFTIALTASEVI

EID2

206

Q8N6I1
TAEEFTDTVFSKIDV

GUCA1A

131

P43080
FSVILDFVESFDVET

MASP2

221

O00187
STVKELTETSAIFED

FMO2

301

Q99518
LTETSAIFEDGTVEE

FMO2

306

Q99518
LVASTTVLELSEAFT

HEPACAM

151

Q14CZ8
FTLTISSLQSEDFAV

IGKV3-15

91

P01624
TSTKAEAERTFAEVT

LAMC1

1441

P11047
VTVTFSDFQDSDLIA

KNG1

556

P01042
EFTVESLIATVTDMF

CYP2C18

281

P33260
EFTIESLENTAVDLF

CYP2C9

281

P11712
VDFESVSSVTALEAL

DNAAF6

21

Q9NQM4
SAETFTLDSLKAVEV

FAM135B

1016

Q49AJ0
EEDASEISVSVVFET

CCDC144A

346

A2RUR9
DSSITSKVTLEIEFD

GRIP1

546

Q9Y3R0
TLLSFLVETEVSFLD

CPNE8

286

Q86YQ8
EFVISLAEKNTTFDT

DHX8

51

Q14562
DTTANEAELFFISVL

OR2B2

191

Q9GZK3
EDAVTAFESIKSVVS

RGPD1

656

P0DJD0
DTTFNEAELFVASVV

OR2G6

191

Q5TZ20
FESVTSIIFLVALSE

GNA14

216

O95837
FSILEEEISAFLISS

PIGB

501

Q92521
FTRTLSDIVSKEDFV

ATP6V1C2

161

Q8NEY4
FVGTAADILEFTSET

TMEM26

181

Q6ZUK4
ISFSRIAETELESTV

SOS2

1066

Q07890
TEDVSSEIFDVSRAT

TSC22D2

41

O75157
QESEVFRVTSTEFIS

SYNJ1

91

O43426
DDVFVASRTTEDLFT

NHSL2

1101

Q5HYW2
EETFSSVSQLATDFI

STK17B

256

O94768
STELSLLADEVITVF

SH3GLB1

321

Q9Y371
SEASVLTVADLADLF

SHPRH

1661

Q149N8
TDIISALVTSTFIIE

STAT5B

321

P51692
ISISQSDDILTFAVA

PKHD1

1661

P08F94
LDFSAVSFLDVSSVR

SLC26A3

651

P40879
IVSTAEILFNDSVFT

ITGAM

1066

P11215
VTTIASVADTIEEKF

RANBP6

521

O60518
FAFLETIVTAVTDEF

SLC6A7

401

Q99884
EFDVLSESAVDFIRT

STK17A

286

Q9UEE5
TDIISALVTSTFIIE

STAT5A

321

P42229
QTLSIFDSEEDITTF

TBC1D9B

96

Q66K14
EETSSLATVFLESVE

ADGRE1

396

Q14246
STAVETDFGLLVTFD

TECTA

426

O75443
LFTATVTDFLAIDAV

SEMA6B

191

Q9H3T3
DSSSVIEIDFLRSDI

ZBTB14

71

O43829
AVASEITVFLFLSDA

SCGB1D4

26

Q6XE38
ELTVELTEETFNATV

TXNDC16

391

Q9P2K2
VLDGAVVSASFDDSV

WDR90

1391

Q96KV7
LALVSFEDVVVTFTG

ZNF599

6

Q96NL3
ESVTFEDVAVTFTQE

ZNF460

11

Q14592
AFFTTAETLTDIVLS

REEP2

46

Q9BRK0
VSLNTVDSIESFVAD

SMU1

36

Q2TAY7
EVFRAAVDLEISSAS

REV1

871

Q9UBZ9
VTTVELDTLAAETAA

RRM1

51

P23921
VSSREEAFTDLSLAF

USP35

586

Q9P2H5
IVTETSFTIDELEEL

TBC1D9

816

Q6ZT07
TEEEIALFSSAVLIS

RORB

366

Q92753
TDGIFETFTIEIIDS

TNC

1461

P24821
EVVSFLTTAIESVDN

TENM4

551

Q6N022
ELFQDSLVFDITVIT

ROS1

1216

P08922
TVIFVSFQLSVATED

PKHD1L1

3936

Q86WI1
QTSILESERETITFF

UNC5D

821

Q6UXZ4
FSVDRIDVVVATTLS

PLCB2

671

Q00722
ASVSFQDVTVEFTRE

ZNF658

6

Q5TYW1
SDVLSSDAVAVTFAD

SLC7A6

296

Q92536
VVAESVSSLTIADAF

GTF3A

6

Q92664
FDFTTTKALSEDSVV

TOGARAM1

1091

Q9Y4F4
SSINALATVTFEDFV

SLC5A12

351

Q1EHB4
VLTFFDLDARVTDST

WDR35

566

Q9P2L0
SVSFKDVTVDFTQEE

ZNF382

6

Q96SR6
SVLASVFLFVAETTA

XK

6

P51811
IKTEFTLTEAVVESS

TERF2

181

Q15554
VSVTFDDVAVTFTQE

ZNF805

11

Q5CZA5
TTILAEFATDDEVSR

TNRC6B

1711

Q9UPQ9
FELVVFLDGTVESTS

KCNJ1

291

P48048
IFITSVDAATTFEEL

PRKCZ

26

Q05513
IFTFECDTIHVSESI

SLC8A3

531

P57103
KITISTDAFEDTVTI

MYOM3

486

Q5VTT5