Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	insulin receptor activity	INSR IGF1R	9.49e-05	3	113	2	GO:0005009
GeneOntologyMolecularFunction	adenosine-phosphate deaminase activity	AMPD2 AMPD3	9.49e-05	3	113	2	GO:0047623
GeneOntologyMolecularFunction	AMP deaminase activity	AMPD2 AMPD3	9.49e-05	3	113	2	GO:0003876
GeneOntologyMolecularFunction	insulin binding	INSR IGF1R	3.14e-04	5	113	2	GO:0043559
GeneOntologyMolecularFunction	ATP-dependent DNA/DNA annealing activity	ZRANB3 TP53	3.14e-04	5	113	2	GO:0036310
Domain	ARM-type_fold	MYBBP1A CLTCL1 NEK10 LRRK2 MROH5 AP4E1 MROH1 UNC45B RRP12 DAAM2 CTNNB1 CTNND2 TARBP1	8.06e-08	339	108	13	IPR016024
Domain	ARM-like	NEK10 LRRK2 MROH5 AP4E1 MROH1 UNC45B RRP12 DAAM2 CTNNB1 CTNND2 TARBP1	4.70e-07	270	108	11	IPR011989
Domain	-	NEK10 LRRK2 MROH5 AP4E1 MROH1 UNC45B RRP12 DAAM2 CTNNB1 CTNND2	6.45e-07	222	108	10	1.25.10.10
Domain	AMPD	AMPD2 AMPD3	9.90e-05	3	108	2	IPR006329
Domain	Tyr_kinase_insulin-like_rcpt	INSR IGF1R	9.90e-05	3	108	2	IPR016246
Domain	A/AMP_deam_AS	AMPD2 AMPD3	1.97e-04	4	108	2	IPR006650
Domain	P-type_TPase_V	ATP13A1 ATP13A3	3.28e-04	5	108	2	IPR006544
Domain	A_DEAMINASE	AMPD2 AMPD3	4.89e-04	6	108	2	PS00485
Domain	A_deaminase	AMPD2 AMPD3	4.89e-04	6	108	2	PF00962
Domain	A/AMP_deaminase_dom	AMPD2 AMPD3	4.89e-04	6	108	2	IPR001365
Domain	Recep_L_domain	INSR IGF1R	6.83e-04	7	108	2	PF01030
Domain	Furin-like	INSR IGF1R	6.83e-04	7	108	2	PF00757
Domain	Rcpt_L-dom	INSR IGF1R	6.83e-04	7	108	2	IPR000494
Domain	Furin-like_Cys-rich_dom	INSR IGF1R	6.83e-04	7	108	2	IPR006211
Domain	-	INSR IGF1R	6.83e-04	7	108	2	3.80.20.20
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	CLTCL1 PRSS56 AGPAT2 LRRK2 MRPL13 ABCC5 ZCCHC17 NCSTN MAST2 FAAP100 ZBTB1 IGF1R MROH1 ARSL ZNF451 MLH1 AGRN DNPEP	7.77e-08	1215	113	18	15146197
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CLTCL1 CTC1 ATP13A1 AGPAT2 TRMT1 ZNF236 MAST2 FAAP100 PLEKHG5 ARHGEF10L IGF1R MROH1 RRP12 HES6 AGRN UVRAG	5.98e-07	1105	113	16	35748872
Pubmed	In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice.	INSR IGF1R PAFAH1B1	2.77e-06	9	113	3	11159375
Pubmed	Modelling bladder cancer in mice: opportunities and challenges.	NCSTN CTNNB1 TP53	9.33e-06	13	113	3	25533675
Pubmed	Prognostic role of beta-catenin and p53 expression in the metastatic progression of sporadic colorectal cancer.	CTNNB1 TP53	1.05e-05	2	113	2	20129645
Pubmed	Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis.	INSR IGF1R	1.05e-05	2	113	2	24809298
Pubmed	A kinase-independent role for unoccupied insulin and IGF-1 receptors in the control of apoptosis.	INSR IGF1R	1.05e-05	2	113	2	21139139
Pubmed	The insulin and IGF1 receptor kinase domains are functional dimers in the activated state.	INSR IGF1R	1.05e-05	2	113	2	25758790
Pubmed	Compounds from the marine sponge Cribrochalina vasculum offer a way to target IGF-1R mediated signaling in tumor cells.	INSR IGF1R	1.05e-05	2	113	2	27384680
Pubmed	Spermidine overrides INSR (insulin receptor)-IGF1R (insulin-like growth factor 1 receptor)-mediated inhibition of autophagy in the aging heart.	INSR IGF1R	1.05e-05	2	113	2	35786404
Pubmed	MYBBP1A suppresses breast cancer tumorigenesis by enhancing the p53 dependent anoikis.	MYBBP1A TP53	1.05e-05	2	113	2	23388179
Pubmed	Insulin-Mediated Signaling Facilitates Resistance to PDGFR Inhibition in Proneural hPDGFB-Driven Gliomas.	INSR IGF1R	1.05e-05	2	113	2	28138037
Pubmed	Insulin-like growth factor I receptors are more abundant than insulin receptors in human micro- and macrovascular endothelial cells.	INSR IGF1R	1.05e-05	2	113	2	14722023
Pubmed	Role of IGF-1R in ameliorating apoptosis of GNE deficient cells.	GNE IGF1R	1.05e-05	2	113	2	29743626
Pubmed	Impaired thermogenesis and adipose tissue development in mice with fat-specific disruption of insulin and IGF-1 signalling.	INSR IGF1R	1.05e-05	2	113	2	22692545
Pubmed	Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers.	CTNNB1 TP53	1.05e-05	2	113	2	20959480
Pubmed	Delta40p53 controls the switch from pluripotency to differentiation by regulating IGF signaling in ESCs.	IGF1R TP53	1.05e-05	2	113	2	21041409
Pubmed	Role of p53 and β-catenin mutations in conjunction with CK19 expression on early tumor recurrence and prognosis of hepatocellular carcinoma.	CTNNB1 TP53	1.05e-05	2	113	2	21061181
Pubmed	Adipocyte Dynamics and Reversible Metabolic Syndrome in Mice with an Inducible Adipocyte-Specific Deletion of the Insulin Receptor.	INSR IGF1R	1.05e-05	2	113	2	28065828
Pubmed	Leucine-973 is a crucial residue differentiating insulin and IGF-1 receptor signaling.	INSR IGF1R	1.05e-05	2	113	2	36548088
Pubmed	Essential role of insulin and insulin-like growth factor 1 receptor signaling in cardiac development and function.	INSR IGF1R	1.05e-05	2	113	2	17189427
Pubmed	[Effects of insulin on expression of insulin receptor and insulin-like growth factor-1 receptor and proliferation in Reh cells].	INSR IGF1R	1.05e-05	2	113	2	22541124
Pubmed	Insulin receptor and IGF1R are not required for oocyte growth, differentiation, and maturation in mice.	INSR IGF1R	1.05e-05	2	113	2	19851056
Pubmed	Beta-catenin and p53 expression in topographic compartments of colorectal cancer and its prognostic value following surgery.	CTNNB1 TP53	1.05e-05	2	113	2	29146051
Pubmed	Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis.	INSR IGF1R	1.05e-05	2	113	2	27905925
Pubmed	Cellular effects of CPT-11 on colon carcinoma cells: dependence on p53 and hMLH1 status.	MLH1 TP53	1.05e-05	2	113	2	12209584
Pubmed	Resveratrol suppresses IGF-1 induced human colon cancer cell proliferation and elevates apoptosis via suppression of IGF-1R/Wnt and activation of p53 signaling pathways.	IGF1R TP53	1.05e-05	2	113	2	20504360
Pubmed	Epidermal insulin/IGF-1 signalling control interfollicular morphogenesis and proliferative potential through Rac activation.	INSR IGF1R	1.05e-05	2	113	2	18650937
Pubmed	A versatile insulin analog with high potency for both insulin and insulin-like growth factor 1 receptors: Structural implications for receptor binding.	INSR IGF1R	1.05e-05	2	113	2	30213860
Pubmed	Epithelial-mesenchymal transition predicts sensitivity to the dual IGF-1R/IR inhibitor OSI-906 in hepatocellular carcinoma cell lines.	INSR IGF1R	1.05e-05	2	113	2	22161861
Pubmed	NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity.	NEK10 TP53	1.05e-05	2	113	2	32561851
Pubmed	A novel approach to identify two distinct receptor binding surfaces of insulin-like growth factor II.	INSR IGF1R	1.05e-05	2	113	2	19139090
Pubmed	AMPD2 regulates GTP synthesis and is mutated in a potentially treatable neurodegenerative brainstem disorder.	AMPD2 AMPD3	1.05e-05	2	113	2	23911318
Pubmed	Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.	INSR IGF1R	1.05e-05	2	113	2	12813019
Pubmed	Epigenetic DNA methylation in the promoters of the Igf1 receptor and insulin receptor genes in db/db mice.	INSR IGF1R	1.05e-05	2	113	2	21474992
Pubmed	Total insulin and IGF-I resistance in pancreatic beta cells causes overt diabetes.	INSR IGF1R	1.05e-05	2	113	2	16642022
Pubmed	β-catenin turnover is regulated by Nek10-mediated tyrosine phosphorylation in A549 lung adenocarcinoma cells.	NEK10 CTNNB1	1.05e-05	2	113	2	38683979
Pubmed	Insulin and IGF-I inhibit GH synthesis and release in vitro and in vivo by separate mechanisms.	INSR IGF1R	1.05e-05	2	113	2	23671263
Pubmed	TRIM23 overexpression is a poor prognostic factor and contributes to carcinogenesis in colorectal cancer.	TRIM23 TP53	1.05e-05	2	113	2	32227572
Pubmed	UVB-induced senescence in human keratinocytes requires a functional insulin-like growth factor-1 receptor and p53.	IGF1R TP53	1.05e-05	2	113	2	18216278
Pubmed	Suppression of Cardiac Autophagy by Hyperinsulinemia in Insulin Receptor-Deficient Hearts Is Mediated by Insulin-Like Growth Factor Receptor Signaling.	INSR IGF1R	1.05e-05	2	113	2	31088290
Pubmed	Human microvascular endothelial cells are sensitive to IGF-I but resistant to insulin at the receptor level.	INSR IGF1R	1.05e-05	2	113	2	18708119
Pubmed	p53 Regulates insulin-like growth factor-I receptor gene expression in uterine serous carcinoma and predicts responsiveness to an insulin-like growth factor-I receptor-directed targeted therapy.	IGF1R TP53	1.05e-05	2	113	2	22033326
Pubmed	Role of insulin receptor in the regulation of glucose uptake in neonatal hepatocytes.	INSR IGF1R	1.05e-05	2	113	2	16644916
Pubmed	siRNA-mediated type 1 insulin-like growth factor receptor silencing induces chemosensitization of a human liver cancer cell line with mutant P53.	IGF1R TP53	1.05e-05	2	113	2	17097318
Pubmed	Reduced insulin-like growth factor I receptor and altered insulin receptor isoform mRNAs in normal mucosa predict colorectal adenoma risk.	INSR IGF1R	1.05e-05	2	113	2	25017244
Pubmed	Differential expression of IGF-I and insulin receptor isoforms in HPV positive and negative human cervical cancer cell lines.	INSR IGF1R	1.05e-05	2	113	2	18711691
Pubmed	[High expression of MRPL13 promotes cell cycle progression and proliferation of gastric cancer cells by inhibiting p53 signaling to affect long-term prognosis].	MRPL13 TP53	1.05e-05	2	113	2	37814870
Pubmed	Differential Expression of IR-A, IR-B and IGF-1R in Endometrial Physiology and Distinct Signature in Adenocarcinoma.	INSR IGF1R	1.05e-05	2	113	2	27088794
Pubmed	Zbtb1 Safeguards Genome Integrity and Prevents p53-Mediated Apoptosis in Proliferating Lymphoid Progenitors.	ZBTB1 TP53	1.05e-05	2	113	2	27402700
Pubmed	Signalling through the insulin receptor and the insulin-like growth factor-I receptor.	INSR IGF1R	1.05e-05	2	113	2	7821728
Pubmed	Nucleolar protein, Myb-binding protein 1A, specifically binds to nonacetylated p53 and efficiently promotes transcriptional activation.	MYBBP1A TP53	1.05e-05	2	113	2	23583237
Pubmed	Obesity and intestinal epithelial deletion of the insulin receptor, but not the IGF 1 receptor, affect radiation-induced apoptosis in colon.	INSR IGF1R	1.05e-05	2	113	2	26251471
Pubmed	Induction of neuronal apoptosis by expression of Hes6 via p53-dependent pathway.	HES6 TP53	1.05e-05	2	113	2	19968968
Pubmed	DNA methylation analysis of cancer-related genes in oral epithelial cells of healthy smokers.	MLH1 TP53	1.05e-05	2	113	2	25791328
Pubmed	Insulin and IGF1 receptors in human cardiac microvascular endothelial cells: metabolic, mitogenic and anti-inflammatory effects.	INSR IGF1R	1.05e-05	2	113	2	22825921
Pubmed	Potential role of MLH1 in the induction of p53 and apoptosis by blocking transcription on damaged DNA templates.	MLH1 TP53	1.05e-05	2	113	2	12939400
Pubmed	The expression and role of hybrid insulin/insulin-like growth factor receptor type 1 in endometrial carcinoma cells.	INSR IGF1R	1.05e-05	2	113	2	20620597
Pubmed	Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier.	INSR IGF1R	1.05e-05	2	113	2	15063759
Pubmed	IGF-I and insulin activate mitogen-activated protein kinase via the type 1 IGF receptor in mouse embryonic stem cells.	INSR IGF1R	1.05e-05	2	113	2	17641087
Pubmed	Beta-catenin expression results in p53-independent DNA damage and oncogene-induced senescence in prelymphomagenic thymocytes in vivo.	CTNNB1 TP53	1.05e-05	2	113	2	18160717
Pubmed	Expression and purification of functional insulin and insulin-like growth factor 1 holoreceptors from mammalian cells.	INSR IGF1R	1.05e-05	2	113	2	28830678
Pubmed	Heterodimerization of glycosylated insulin-like growth factor-1 receptors and insulin receptors in cancer cells sensitive to anti-IGF1R antibody.	INSR IGF1R	1.05e-05	2	113	2	22438913
Pubmed	Insulin and IGF-1 have both overlapping and distinct effects on CD4+ T cell mitochondria, metabolism, and function.	INSR IGF1R	1.05e-05	2	113	2	38383709
Pubmed	Phosphorylation of p53 by LRRK2 induces microglial tumor necrosis factor α-mediated neurotoxicity.	LRRK2 TP53	1.05e-05	2	113	2	27914807
Pubmed	Thyrocyte-specific deletion of insulin and IGF-1 receptors induces papillary thyroid carcinoma-like lesions through EGFR pathway activation.	INSR IGF1R	1.05e-05	2	113	2	30070361
Pubmed	Homozygous receptors for insulin and not IGF-1 accelerate intimal hyperplasia in insulin resistance and diabetes.	INSR IGF1R	1.05e-05	2	113	2	31562314
Pubmed	Sporadic childhood hepatoblastomas show activation of beta-catenin, mismatch repair defects and p53 mutations.	CTNNB1 TP53	1.05e-05	2	113	2	17962810
Pubmed	RNA content in the nucleolus alters p53 acetylation via MYBBP1A.	MYBBP1A TP53	1.05e-05	2	113	2	21297583
Pubmed	Insulin receptors in beta-cells are critical for islet compensatory growth response to insulin resistance.	INSR IGF1R	1.05e-05	2	113	2	17416680
Pubmed	High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy.	INSR IGF1R	1.05e-05	2	113	2	21177763
Pubmed	Changes in insulin and IGF-I receptor expression during differentiation of human preadipocytes.	INSR IGF1R	1.05e-05	2	113	2	18693051
Pubmed	Insulin/IGF-1 hybrid receptor expression on human platelets: consequences for the effect of insulin on platelet function.	INSR IGF1R	1.05e-05	2	113	2	19817984
Pubmed	Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy.	INSR IGF1R	1.05e-05	2	113	2	19744489
Pubmed	Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior.	INSR IGF1R	1.05e-05	2	113	2	30765523
Pubmed	Functional collaboration of insulin-like growth factor-1 receptor (IGF-1R), but not insulin receptor (IR), with acute GH signaling in mouse calvarial cells.	INSR IGF1R	1.05e-05	2	113	2	24302626
Pubmed	Novel nuclear localization and potential function of insulin-like growth factor-1 receptor/insulin receptor hybrid in corneal epithelial cells.	INSR IGF1R	1.05e-05	2	113	2	22879999
Pubmed	Evaluation of CTNNB1 and TP53 variability in patients with hepatocellular carcinoma and occult hepatitis B virus infection.	CTNNB1 TP53	1.05e-05	2	113	2	26341700
Pubmed	AMP deaminase 3 plays a critical role in remote reperfusion lung injury.	AMPD2 AMPD3	1.05e-05	2	113	2	23542464
Pubmed	A functional assessment of insulin/insulin-like growth factor-I hybrid receptors.	INSR IGF1R	1.05e-05	2	113	2	7895674
Pubmed	The nucleolar protein Myb-binding protein 1A (MYBBP1A) enhances p53 tetramerization and acetylation in response to nucleolar disruption.	MYBBP1A TP53	1.05e-05	2	113	2	24375404
Pubmed	Reduced membranous beta-catenin protein expression is associated with metastasis and poor prognosis in squamous cell carcinoma of the esophagus.	CTNNB1 TP53	1.05e-05	2	113	2	18455580
Pubmed	Combined and individual tumor-specific expression of insulin-like growth factor-I receptor, insulin receptor and phospho-insulin-like growth factor-I receptor/insulin receptor in primary breast cancer: Implications for prognosis in different treatment groups.	INSR IGF1R	1.05e-05	2	113	2	28030849
Pubmed	Insulin-like growth factor type 1 receptor and insulin receptor isoform expression and signaling in mammary epithelial cells.	INSR IGF1R	1.05e-05	2	113	2	19406949
Pubmed	Placental glycogen stores are increased in mice with H19 null mutations but not in those with insulin or IGF type 1 receptor mutations.	INSR IGF1R	1.05e-05	2	113	2	19524295
Pubmed	Hepatitis B virus-associated hepatocellular carcinoma from India: role of viral genotype and mutations in CTNNB1 (beta-catenin) and TP53 genes.	CTNNB1 TP53	1.05e-05	2	113	2	20963515
Pubmed	Male Brown Fat-Specific Double Knockout of IGFIR/IR: Atrophy, Mitochondrial Fission Failure, Impaired Thermogenesis, and Obesity.	INSR IGF1R	1.05e-05	2	113	2	29040448
Pubmed	Influence of the interaction between p53 and ZNF568 on mitochondrial oxidative phosphorylation.	ZNF568 TP53	1.05e-05	2	113	2	38944084
Pubmed	Apolipoprotein C3 and circulating mediators of preadipocyte proliferation in states of lipodystrophy.	INSR IGF1R	1.05e-05	2	113	2	35964946
Pubmed	Endothelial Cell Mediated Promotion of Ciliated Cell Differentiation of Human Airway Basal Cells via Insulin and Insulin-Like Growth Factor 1 Receptor Mediated Signaling.	INSR IGF1R	1.05e-05	2	113	2	28050756
Pubmed	IGF1R Expression in Ovarian Granulosa Cells Is Essential for Steroidogenesis, Follicle Survival, and Fertility in Female Mice.	INSR IGF1R	1.05e-05	2	113	2	28407051
Pubmed	BI 885578, a Novel IGF1R/INSR Tyrosine Kinase Inhibitor with Pharmacokinetic Properties That Dissociate Antitumor Efficacy and Perturbation of Glucose Homeostasis.	INSR IGF1R	1.05e-05	2	113	2	26438154
Pubmed	Development of a Quantitative PCR Assay for Detection of Human Insulin-Like Growth Factor Receptor and Insulin Receptor Isoforms.	INSR IGF1R	1.05e-05	2	113	2	26862994
Pubmed	The signaling potential of the receptors for insulin and insulin-like growth factor I (IGF-I) in 3T3-L1 adipocytes: comparison of glucose transport activity, induction of oncogene c-fos, glucose transporter mRNA, and DNA-synthesis.	INSR IGF1R	1.05e-05	2	113	2	1660482
Pubmed	Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes.	INSR IGF1R	1.05e-05	2	113	2	25246545
Pubmed	Lipodystrophy Due to Adipose Tissue-Specific Insulin Receptor Knockout Results in Progressive NAFLD.	INSR IGF1R	1.05e-05	2	113	2	27207510
Pubmed	Differential Roles of Insulin and IGF-1 Receptors in Adipose Tissue Development and Function.	INSR IGF1R	1.05e-05	2	113	2	27207537
Pubmed	Ser-249 TP53 and CTNNB1 mutations in circulating free DNA of Egyptian patients with hepatocellular carcinoma versus chronic liver diseases.	CTNNB1 TP53	1.05e-05	2	113	2	18313840
Pubmed	Preclinical and first-in-human phase I studies of KW-2450, an oral tyrosine kinase inhibitor with insulin-like growth factor receptor-1/insulin receptor selectivity.	INSR IGF1R	1.05e-05	2	113	2	26850678
Pubmed	Loss of mitochondrial Ca2+ response and CaMKII/ERK activation by LRRK2R1441G mutation correlate with impaired depolarization-induced mitophagy.	CAMK2A LRRK2	1.05e-05	2	113	2	39390438
GeneFamily	Parkinson disease associated genes\|ATPase orphan transporters	ATP13A1 ATP13A3	1.92e-04	5	80	2	1213
GeneFamily	Adenosine deaminase family	AMPD2 AMPD3	2.87e-04	6	80	2	1302
GeneFamily	Maestro heat like repeat containing	MROH5 MROH1	1.04e-03	11	80	2	636
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF560 ZNF236 ZBTB1 ZNF568 RLF ZNF599 GFI1B ZNF34 KLF13 ZNF451	1.23e-03	718	80	10	28
GeneFamily	Dyneins, axonemal	DNAH7 DNAH9	2.52e-03	17	80	2	536
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	GNE ZZZ3 ZNF451 PAFAH1B1 OTUD4 ATP13A3 ADGRL2	2.88e-06	145	111	7	M1810
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	DENND1B BAZ2A ZBED6 POLR1B MED23 AQR	9.46e-06	193	112	6	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	KIF6 NEK10 RFX2 DNAH7 TTC6 DNAH9	1.00e-05	195	112	6	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	AMPD3 KIF6 DNAH7 HES6 CCDC171 DNAH9	1.06e-05	197	112	6	861e8df9bd74dc5e17bafdc1fb3fef546753c73a
ToppCell	Control-Lymphoid-Plasma,_B_cells\|Lymphoid / Condition, Lineage and Cell class	CLIP2 LRRK2 PIK3R6 IGHG3 PLCG2 UVRAG	1.09e-05	198	112	6	d2b7dd7919019dbfa18cfa52e64f4d27e56b9df6
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	KIF6 NEK10 INSR DNAH7 TTC6 DNAH9	1.09e-05	198	112	6	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	KIF6 HCN4 NEK10 DNAH7 TTC6 DNAH9	1.13e-05	199	112	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	severe-immature_Neutrophil\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	AMPD3 CLTCL1 IGF1R ELANE DAAM2 PLCG2	1.16e-05	200	112	6	a9b87accdaa6956116ab82427e1330e8f007ef94
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 NEK10 RFX2 DNAH7 DNAH9	4.00e-05	151	112	5	8216462e723fec2797387929dde095370947e10a
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high\|E18.5-samps / Age Group, Lineage, Cell class and subclass	AMPD2 RASGEF1A INTS3 UNC45B HFM1	4.40e-05	154	112	5	212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INSR QRICH2 TTC6 ARHGEF10L TARBP1	5.93e-05	164	112	5	d6f71d804bb65301c02ea4e6673e20688b5fcd5b
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 KIF6 NEK10 DNAH7 DNAH9	6.28e-05	166	112	5	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AMPD3 CTC1 TRIM23 PTPRM CCDC171	7.43e-05	172	112	5	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NEK10 INSR CLEC14A RRP12 ADGRL2	7.43e-05	172	112	5	c3a99828838af3b85c8c885d69cc8018f55ced50
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTC1 TRIM23 PTPRM ZNF451 CCDC171	7.43e-05	172	112	5	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CTC1 TRIM23 PTPRM ZNF451 CCDC171	7.43e-05	172	112	5	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRMT1 ABCC5 ARHGEF10L BAZ2A CLDN20	7.63e-05	173	112	5	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRPA1 SGCA CAMK2A HFM1 ADGRL2	7.63e-05	173	112	5	75e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRMT1 ABCC5 ARHGEF10L BAZ2A CLDN20	7.63e-05	173	112	5	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	TRPA1 SGCA CAMK2A HFM1 ADGRL2	7.63e-05	173	112	5	26e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-mature_enterocytic-Paneth\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAMP1 NEK10 AGPAT2 ARSL HES6	7.84e-05	174	112	5	b4483d7d9f22f09ed7fa0b72305434a47ccaade0
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	8.73e-05	178	112	5	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	9.44e-05	181	112	5	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	9.69e-05	182	112	5	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	CFAP47 KIF6 NEK10 DNAH7 DNAH9	9.69e-05	182	112	5	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	RASGEF1A PLEKHG5 PIK3R6 PTPRM CLEC14A	9.69e-05	182	112	5	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.02e-04	184	112	5	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	15-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	NEK10 RFX2 OTUD4 HES6 CCDC171	1.05e-04	185	112	5	9a8b8360d99375b726ca8e3c9a3f9b08919892d7
ToppCell	COVID-19-kidney-FLT1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	INSR RFX2 PLCG2 CTNNB1 ADGRL2	1.05e-04	185	112	5	673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.05e-04	185	112	5	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.05e-04	185	112	5	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.05e-04	185	112	5	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.10e-04	187	112	5	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	P03-Endothelial-capillary_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.13e-04	188	112	5	ede354ca550840d8f0c8dac22d8ce1f1d325886a
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.13e-04	188	112	5	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.13e-04	188	112	5	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.13e-04	188	112	5	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.16e-04	189	112	5	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.16e-04	189	112	5	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	PND07-28-samps-Endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.16e-04	189	112	5	eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCell	CTRL-Lymphoid-B_cell\|Lymphoid / Disease state, Lineage and Cell class	CLIP2 LRRK2 PLCG2 SHISAL2A UVRAG	1.16e-04	189	112	5	14f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.16e-04	189	112	5	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.16e-04	189	112	5	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.16e-04	189	112	5	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	PND07-28-samps-Endothelial-Postnatal_endothelial\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.16e-04	189	112	5	d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCell	PND01-03-samps-Endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.19e-04	190	112	5	1357bd4527399d7013ee33272bda7453f472999a
ToppCell	PND01-03-samps-Endothelial-Postnatal_endothelial\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.19e-04	190	112	5	5130fb325f80f591b9b36beacb8072c4472304f2
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RAMP1 NEK10 DNAH7 HES6 DNAH9	1.22e-04	191	112	5	683e5c7e6173644f01e67c98ab7b75d7cb9cce99
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 NEK10 DNAH7 TTC6 CTNND2	1.22e-04	191	112	5	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.22e-04	191	112	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.22e-04	191	112	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.22e-04	191	112	5	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSR RASGEF1A PTPRM UNC45B CLEC14A	1.25e-04	192	112	5	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSR RASGEF1A PTPRM UNC45B CLEC14A	1.25e-04	192	112	5	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.25e-04	192	112	5	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.25e-04	192	112	5	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.25e-04	192	112	5	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	Control-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.28e-04	193	112	5	0e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIK3R6 PTPRM CLEC14A CTNND2 ADGRL2	1.28e-04	193	112	5	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	LPS_only-Endothelial-Endothelial-Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PIK3R6 PTPRM CLEC14A CTNND2 ADGRL2	1.28e-04	193	112	5	af5108260783e69a7d67896c5bf64f862525926d
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.28e-04	193	112	5	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	PND10-Endothelial-Endothelial_blood-vessel\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.28e-04	193	112	5	1d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.28e-04	193	112	5	097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCell	PND10-Endothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.28e-04	193	112	5	f3c743b340fc588bc8effd375b12e2c7cbfa49d2
ToppCell	PND14-Endothelial\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.31e-04	194	112	5	cee89d4340738f09d07a159cd6aeee4300776988
ToppCell	PND14-Endothelial-Endothelial_blood-vessel\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.31e-04	194	112	5	32962060d80f3edffbe9f0ecad3000c3a9817865
ToppCell	PND07-Endothelial-Endothelial_blood-vessel\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.31e-04	194	112	5	12496bc964d1c572241410524a89ca1a9fdb7e34
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A AGRN	1.31e-04	194	112	5	92a8e6e3e3f6fd9dacb723b58e7a8b63473e403e
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.31e-04	194	112	5	46e36817fd1ed27af8013375214c38c9a9271640
ToppCell	PND07-Endothelial\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.31e-04	194	112	5	d1080c86884916c22894b27994141463f5919812
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.31e-04	194	112	5	958e648138676d46698090b4046cb484083ae449
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 NEK10 DNAH7 PLCG2 DNAH9	1.31e-04	194	112	5	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RASGEF1A PTPRM UNC45B CLEC14A ADGRL2	1.31e-04	194	112	5	c6cee7d15af76f9a60d7f414ef0bcc1735c47b7a
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSR RASGEF1A PTPRM UNC45B CLEC14A	1.34e-04	195	112	5	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	TCGA-Thryoid-Primary_Tumor\|TCGA-Thryoid / Sample_Type by Project: Shred V9	INSR LRRK2 GRB7 MAST2 AGRN	1.34e-04	195	112	5	7cdee2ae90edf15e4cbcf70797b8caf1f037b0ef
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma\|TCGA-Thryoid / Sample_Type by Project: Shred V9	INSR LRRK2 GRB7 MAST2 AGRN	1.34e-04	195	112	5	b61b8c931bd0ca3678486653ae1d7e9915c696c7
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CFAP47 NEK10 DNAH7 TTC6 DNAH9	1.37e-04	196	112	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	NS-moderate-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 NEK10 RFX2 DNAH7 DNAH9	1.40e-04	197	112	5	71fea4aa6ce96c7693fa94792d08770622873850
ToppCell	5'-GW_trimst-1-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAMP1 GRB7 TTC6 ARSL CTNND2	1.40e-04	197	112	5	6ee6939c492bedf1f96a715da7a26a4c55a7c36f
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.40e-04	197	112	5	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	INSR IGF1R CLEC14A ADGRL2 AGRN	1.44e-04	198	112	5	0a4626b51ba8b52acbaf616f0ced850079cd7149
ToppCell	IPF-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	INSR RFX2 RRP12 OTUD4 NLK	1.44e-04	198	112	5	b8bd1ba268480f54451648e01631b615a3401144
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.47e-04	199	112	5	2498237b9e895ca4826a3378d9d40989968df72b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.47e-04	199	112	5	542ec45c931b40738df1f3777b00c83be33a514a
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PTPRM CLEC14A ATP13A3 PLCG2 CTNND2	1.47e-04	199	112	5	9735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCell	10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	INSR PIK3R6 CLEC14A PLCG2 AGRN	1.47e-04	199	112	5	1295f34a350bf48987e2fad411aaac3630efd3f1
ToppCell	Tracheal-NucSeq-Stromal-Schwann-Schwann_Myelinating\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RAMP1 PLEKHG5 ARSL TRPM3 CLEC14A	1.47e-04	199	112	5	4e4bdcd2e8b518156d5ebd294804180acaa3566b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	INSR PTPRM CLEC14A GNAT1 ADGRL2	1.47e-04	199	112	5	63c01e8961f48ed1bed4ab619cacf318cd6de7b9
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	KIF6 NEK10 DNAH7 TTC6 DNAH9	1.51e-04	200	112	5	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	Biopsy_Other_PF-Epithelial-Differentiating_Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.51e-04	200	112	5	f7b4581d958afbd68f9045af619aaca0ab463439
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.51e-04	200	112	5	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Biopsy_Control_(H.)-Epithelial-Differentiating_Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CFAP47 NEK10 DNAH7 HES6 DNAH9	1.51e-04	200	112	5	a552a99f5e4fa00dfb7775e5a3e1f62f1530d104
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related-Oligodendrocyte/OPC\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZZZ3 SH3GLB1 HES6 DNAH9 TP53	1.51e-04	200	112	5	4db894cfb80fd1f9e01133f345eefd78edd4bc43
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-OPC_related\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	ZZZ3 SH3GLB1 HES6 DNAH9 TP53	1.51e-04	200	112	5	d46a19274c2836ce7494790ce513764dedcadc79
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP47 KIF6 NEK10 DNAH7 DNAH9	1.51e-04	200	112	5	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
Disease	diabetic neuropathy (implicated_via_orthology)	TRPA1 INSR IGF1R	1.83e-05	14	111	3	DOID:9743 (implicated_via_orthology)
Disease	Adrenocortical carcinoma	IGF1R CTNNB1 TP53	4.06e-05	18	111	3	C0206686
Disease	Central Nervous System Neoplasms	MLH1 TP53	8.37e-05	4	111	2	C0085136
Disease	gestational diabetes (biomarker_via_orthology)	INSR IGF1R	1.39e-04	5	111	2	DOID:11714 (biomarker_via_orthology)
Disease	pontocerebellar hypoplasia (implicated_via_orthology)	AMPD2 AMPD3	1.39e-04	5	111	2	DOID:0060264 (implicated_via_orthology)
Disease	lung carcinoma (implicated_via_orthology)	MLH1 CTNNB1	1.39e-04	5	111	2	DOID:3905 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of ovary	MLH1 CTNNB1 TP53	1.76e-04	29	111	3	C0496920
Disease	Ovarian Carcinoma	MLH1 CTNNB1 TP53	1.95e-04	30	111	3	C0029925
Disease	colorectal cancer (biomarker_via_orthology)	CTNNB1 TP53	2.08e-04	6	111	2	DOID:9256 (biomarker_via_orthology)
Disease	Ovarian Mucinous Adenocarcinoma	NEK10 LRRK2 MAST2	2.16e-04	31	111	3	C1335167
Disease	HEPATOCELLULAR CARCINOMA	CTNNB1 TP53	4.96e-04	9	111	2	114550
Disease	Adult Hepatocellular Carcinoma	CTNNB1 TP53	4.96e-04	9	111	2	C0279607
Disease	Hepatocellular carcinoma	CTNNB1 TP53	4.96e-04	9	111	2	cv:C2239176
Disease	Glioma	CTNNB1 TP53	4.96e-04	9	111	2	cv:C0017638
Disease	alcohol dependence (implicated_via_orthology)	INSR IGF1R	4.96e-04	9	111	2	DOID:0050741 (implicated_via_orthology)
Disease	urinary bladder cancer (implicated_via_orthology)	NCSTN CTNNB1	4.96e-04	9	111	2	DOID:11054 (implicated_via_orthology)
Disease	Acute Confusional Senile Dementia	INSR NCSTN IGF1R PLCG2	5.42e-04	99	111	4	C0546126
Disease	Alzheimer's Disease, Focal Onset	INSR NCSTN IGF1R PLCG2	5.42e-04	99	111	4	C0750900
Disease	Alzheimer Disease, Early Onset	INSR NCSTN IGF1R PLCG2	5.42e-04	99	111	4	C0750901
Disease	Presenile dementia	INSR NCSTN IGF1R PLCG2	5.42e-04	99	111	4	C0011265
Disease	Alzheimer Disease, Late Onset	INSR NCSTN IGF1R PLCG2	5.42e-04	99	111	4	C0494463
Disease	Familial Alzheimer Disease (FAD)	INSR NCSTN IGF1R PLCG2	5.63e-04	100	111	4	C0276496
Disease	platelet component distribution width	LRRK2 ABCC5 RFX2 GFI1B IGF1R TRPM3 BAZ2A MLH1 ATP13A3 PLCG2	5.73e-04	755	111	10	EFO_0007984
Disease	Alzheimer's Disease	INSR NCSTN IGF1R PLCG2	5.85e-04	101	111	4	C0002395
Disease	Gastric Adenocarcinoma	INSR MLH1 CTNNB1	6.55e-04	45	111	3	C0278701
Disease	Adrenal Gland Neoplasms	CTNNB1 TP53	7.54e-04	11	111	2	C0001624
Disease	sleep disorder (implicated_via_orthology)	INSR IGF1R	7.54e-04	11	111	2	DOID:535 (implicated_via_orthology)
Disease	Adrenal Cancer	CTNNB1 TP53	7.54e-04	11	111	2	C0750887
Disease	mismatch repair cancer syndrome (is_implicated_in)	MLH1 TP53	9.03e-04	12	111	2	DOID:0112182 (is_implicated_in)
Disease	diastolic blood pressure, systolic blood pressure	HORMAD2 HCN4 CLIP2 NEK10 DNAH7 DENND1B TRPM3 HERPUD2 TP53	9.83e-04	670	111	9	EFO_0006335, EFO_0006336
Disease	cup-to-disc ratio measurement	HORMAD2 KIF6 SGCA PRSS56 CLVS1 IGF1R CCDC171	1.23e-03	430	111	7	EFO_0006939
Disease	nephroblastoma (is_implicated_in)	IGF1R CTNNB1	1.24e-03	14	111	2	DOID:2154 (is_implicated_in)
Disease	Colorectal Carcinoma	ZNF560 ABCC5 ARHGEF10L GFI1B ZZZ3 MLH1 CTNNB1 CTNND2 TP53	1.36e-03	702	111	9	C0009402
Disease	Alzheimer's disease (biomarker_via_orthology)	INSR IGF1R CTNNB1	1.38e-03	58	111	3	DOID:10652 (biomarker_via_orthology)
Disease	eosinophil count	RAMP1 RASGEF1A ABCC5 DNAH7 ZNF568 TTC6 GFI1B DENND1B RRP12 POLR1B HFM1 UVRAG TP53 IL9R	1.40e-03	1488	111	14	EFO_0004842
Disease	renal cell carcinoma (is_marker_for)	INSR MLH1 CTNNB1 TP53	1.41e-03	128	111	4	DOID:4450 (is_marker_for)
Disease	inflammatory bowel disease	HORMAD2 CAMK2A LRRK2 GRB7 DENND1B PLCG2 DNPEP	1.57e-03	449	111	7	EFO_0003767
Disease	ulcerative colitis	HORMAD2 CAMK2A GRB7 DENND1B PLCG2 DNPEP	1.71e-03	335	111	6	EFO_0000729
Disease	pre-malignant neoplasm (biomarker_via_orthology)	INSR TP53	1.84e-03	17	111	2	DOID:0060071 (biomarker_via_orthology)
Disease	MHPG measurement, 5-HIAA measurement	CLEC14A CCDC171	1.84e-03	17	111	2	EFO_0005132, EFO_0005133
Disease	Neoplastic Cell Transformation	IGF1R CTNNB1 CTNND2 TP53	1.91e-03	139	111	4	C0007621
Disease	opioid dependence	RAMP1 CLVS1 PLCG2 CTNND2 ADGRL2	2.06e-03	237	111	5	EFO_0005611
Disease	Uterine leiomyoma, estrogen-receptor positive breast cancer	NEK10 TP53	2.06e-03	18	111	2	EFO_1000649, HP_0000131
Disease	Malignant neoplasm of endometrium	MLH1 CTNNB1	2.06e-03	18	111	2	C0007103
Disease	Carcinoma in situ of endometrium	MLH1 CTNNB1	2.06e-03	18	111	2	C0346191
Disease	Hemangiosarcoma	CTNNB1 TP53	2.06e-03	18	111	2	C0018923
Disease	Congenital hernia of foramen of Morgagni	INSR IGF1R	2.30e-03	19	111	2	C0265699
Disease	Congenital hernia of foramen of Bochdalek	INSR IGF1R	2.30e-03	19	111	2	C0265700
Disease	Malignant neoplasm of breast	KIF6 MRPL13 GRB7 FEM1C RFX2 ADAR IGF1R UNC45B CTNNB1 DNAH9 TP53	2.43e-03	1074	111	11	C0006142
Disease	prostate adenocarcinoma (is_implicated_in)	INSR IGF1R	2.55e-03	20	111	2	DOID:2526 (is_implicated_in)
Disease	brain age measurement	EEF1AKMT4-ECE2 EEF1AKMT4	2.55e-03	20	111	2	EFO_0010602
Disease	Endometrial Carcinoma	IGF1R MLH1 CTNNB1	2.56e-03	72	111	3	C0476089
Disease	Congenital diaphragmatic hernia	INSR IGF1R	2.81e-03	21	111	2	C0235833
Disease	cervical squamous cell carcinoma (is_marker_for)	ADAR TP53	3.08e-03	22	111	2	DOID:3744 (is_marker_for)
Disease	Lewy Body Disease	INSR IGF1R	3.08e-03	22	111	2	C0752347

Protein segments in the cluster

Peptide	Gene	Start	Entry
HCHSMFQIALSSRVA	ARHGEF10L	371	Q9HCE6
ALIVHADCFLMRNHT	ARSL	246	P51690
TAEAVVTCRNHHVAA	CTC1	1081	Q2NKJ3
AVDERHHSVLMSLLC	DNPEP	221	Q9ULA0
HDMVATHSTVRVSVC	ATP13A3	261	Q9H7F0
SMRNHHSDLTFCEII	BAZ2A	1791	Q9UIF9
ETHRALASCHSLMQL	ATP13A1	566	Q9HD20
ECVANHMRAVENTLH	CCDC171	1141	Q6TFL3
SECMLHVHACTHQIS	AGRN	576	O00468
MDSSQLIHCRELVAH	CCNI	231	Q14094
CSHLTNFAILMAHRE	ADGRL2	821	O95490
AVEALCSSQHTHMIE	CLIP2	796	Q9UDT6
AMTCTHAALKRHDLV	AQR	1036	O60306
NIRKVDTHIHASSCM	AMPD2	411	Q01433
EHPIARMIVDCVSSH	BBS10	61	Q8TAM1
LDHRMTEVHRSACGA	CTNND2	601	Q9UQB3
VRKVDTHIHAAACMN	AMPD3	311	Q01432
HEFTISLDTCMRQHA	AP4E1	576	Q9UPM8
HVQAARATMVLACVL	CLDN20	76	P56880
LLAHHLFMTTACQEA	RAMP1	16	O60894
HSQSRHVEVRMACIH	OTUD4	56	Q01804
EAAAMRRQLLAHFHC	QRICH2	1411	Q9H0J4
ALQHVQASCDEAHKM	INTS3	951	Q68E01
IQCMHEVHTFVSTCQ	HES6	101	Q96HZ4
RCMKTLNAHEHFVTS	PAFAH1B1	371	P43034
QLFSHMHAVISTATC	NCSTN	216	Q92542
DLEVSNRHGHTCLMI	FEM1C	141	Q96JP0
LRSMDHATCESRIHT	DAAM2	161	Q86T65
AATVQHTMACHLVKR	OSGEPL1	286	Q9H4B0
CALRHLTSRHQEAEM	CTNNB1	466	P35222
MHVVCAQSHIHEQSV	OR10W1	176	Q8NGF6
HMLAVIRLSCIDSNH	OR10X1	196	Q8NGY0
VNRMHESLHLFNSIC	GNAT1	236	P11488
THVHSQERSFECRMC	GFI1B	211	Q5VTD9
MATAQLSHCITIHKA	HORMAD2	1	Q8N7B1
IEAMVHCASTRHPAA	KIAA1109	1641	Q2LD37
DVLHQKMTETCATAH	KIAA1109	2816	Q2LD37
ASVMKEFNCHHVVRL	IGF1R	1051	P08069
FMEANRNTVTCHHEL	NEK10	816	Q6ZWH5
MAVALAHIRHVSCDL	PDE12	471	Q6L8Q7
AAHALHVTCVELMAL	MED23	1101	Q9ULK4
EIFMRHGCHTVIASR	DECR2	46	Q9NUI1
MNQASTRSHCIFTIH	KIF6	216	Q6ZMV9
IVECMVATHHNSRNA	LRRK2	2151	Q5S007
VHRDLAARNCMVAHD	INSR	1156	P06213
SQHMTEVVRRCPHHE	TP53	166	P04637
EEHCSVEQQRHMAKA	PLCG2	406	P16885
ATHEAVHLLCRMLVF	NLK	396	Q9UBE8
QARADVIHGCLHSIM	MROH1	861	Q8NDA8
DICRAHHAVVGRMQT	FAAP100	796	Q0VG06
HVCEMLVQRAHALSD	GRB7	126	Q14451
VQHDREMAHCAHRVQ	HCN4	746	Q9Y3Q4
EMAHCAHRVQAAASA	HCN4	751	Q9Y3Q4
MRQVARSVFGHICSH	MYBBP1A	666	Q9BQG0
VSMSRLHFCDSNIIH	OR8H3	161	Q8N146
MLACRDTVESSLHRH	HFM1	681	A2PYH4
FADCTMLTIAHRLHT	ABCC5	1376	O15440
SVVVAAMQARHAHVP	EEF1AKMT4-ECE2	91	P0DPD8
HDQIAMLSHRCFNTL	ADAR	841	P55265
TRSAEQHLISMCEDH	GNE	161	Q9Y223
FIDHCRSQLHVVLAM	DNAH7	2461	Q8WXX0
SFIHHQVIEMARDCL	MAST2	356	Q6P0Q8
AAECLVSMSSRAVVH	KLF13	11	Q9Y2Y9
MSAAHCVANVNVRAV	ELANE	66	P08246
NIFSCSVMHEALHNR	IGHG3	351	P01860
QDEYHMVHLVCTSRT	HERPUD2	76	Q9BSE4
HMICEDVRRHAHSLQ	DNAH9	156	Q9NYC9
LHEVVSLCHMTSDFQ	DENND1B	746	Q6P3S1
AMTRTHNHRSCEEPV	CFAP47	566	Q6ZTR5
DTCHRAMRTTFLHIS	AGPAT2	246	O15120
VAMEIQHRSHECRGS	PRSS56	56	P0CW18
CEMLRHQRTVDVFHA	PTPRM	1406	P28827
VHTGNMFREHVCRSS	OR14I1	156	A6ND48
SEKAHERQRAVHSCM	MROH5	596	Q6ZUA9
GLMVRCDRHHTSSAI	UVRAG	461	Q9P2Y5
ACHEMALRIVLHSLD	TRMT1	286	Q9NXH9
CNHQRAVHLFMASLE	LIPI	251	Q6XZB0
HCEATVDVVMNLQFH	RFX2	376	P48378
AQQTPETCMRHVVSH	PIK3R6	181	Q5UE93
ETCMRHVVSHALQAA	PIK3R6	186	Q5UE93
RLLHHCFMATVTTSD	SHISAL2A	156	Q6UWV7
AHHLRCLNDFVEAQM	SH3GLB1	221	Q9Y371
CMNRHVHVKDDFVRS	SHLD2	81	Q86V20
TFHHCMSGREQVSLV	IL9R	121	Q01113
ISHRSTVASCMHRQE	CAMK2A	271	Q9UQM7
LREMLHNHSFVGCVN	MLH1	521	P40692
AMVHHANSSCVRNAF	RIG	41	Q13278
SVVVAAMQARHAHVP	EEF1AKMT4	91	P0DPD7
KRDLATSDIQMVHHC	SGCA	321	Q16586
LSHVLVTACAMQAFH	RRP12	336	Q5JTH9
MFDRHTSLVGCQVIH	CLTCL1	141	P53675
HHATMKRQAAEEACI	CLEC14A	41	Q86T13
MHVKHTSSNLERECS	CLVS1	306	Q8IUQ0
GSVERFIHHVNACMR	PLEKHG5	516	O94827
MCSGHQARATVILHA	UNC45B	206	Q8IWX7
SHMELTAHFRVHCRN	ZNF451	326	Q9Y4E5
AFCDSSSLIQHMRIH	ZNF599	431	Q96NL3
IVNTTDGCHETMLHR	TRPA1	301	O75762
LHVCKTMHDSVNALT	VPS35L	611	Q7Z3J2
QCSVFIIHMRSHTGE	ZNF568	401	Q3ZCX4
SLCHATAMCHHRINE	TTC6	211	Q86TZ1
TAMCHHRINEFEEAV	TTC6	216	Q86TZ1
QGLVHRTHMSSCRVD	ZCCHC17	41	Q9NP64
IVSHMDSLDNHRCRG	RASGEF1A	241	Q8N9B8
KTRAEALHMCVEHSE	RLF	1531	Q13129
AAKHRDFIAHTCSQM	TRPM3	766	Q9HCF6
VECAMRALHFSSRHN	TTC17	246	Q96AE7
SDCGDHVVIMNTRHI	MRPL13	51	Q9BYD1
RHMISHLSAGETICQ	ZBTB1	651	Q9Y2K1
SIENMLVAARKTCHH	ZBED6	601	P86452
ECDRAFSSAAVLMHH	ZNF236	1661	Q9UL36
HCTMITHQILLRGAA	TARBP1	516	Q13395
CLVCRESQEHQTHAM	TRIM4	106	Q9C037
TMCSQHQVHAIEFVC	TRIM23	176	P36406
SMHCVREEHSAVNMN	POLR1B	211	Q9H9Y6
DRSCFHSHMNTAVED	ZZZ3	761	Q8IYH5
TSSACLRIHMRTHTE	ZNF560	526	Q96MR9
SCEFINHRRMHSGEI	ZNF34	291	Q8IZ26
HHLSMLQACTEAVIE	ZRANB3	346	Q5FWF4