Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SH3 domain binding	ESPN PDCD6IP WIPF1 ARHGAP17 CBLB SYNGAP1 FMN1	1.35e-05	143	109	7	GO:0017124
GeneOntologyMolecularFunction	chromatin binding	SMARCA5 MAZ KDM6B PHC1 PWWP2A CCNT1 NCOR2 SETDB1 MTA1 SKOR2 MLLT1 MBD5 MNT	1.95e-04	739	109	13	GO:0003682
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	RIN3 ARHGEF5 RANBP3 ARHGAP17 CHRM4 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	4.60e-04	507	109	10	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	RIN3 ARHGEF5 RANBP3 ARHGAP17 CHRM4 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	4.60e-04	507	109	10	GO:0030695
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase inhibitor activity	WASHC1 WASH3P	8.09e-04	8	109	2	GO:0141039
GeneOntologyMolecularFunction	GTPase activator activity	RIN3 RANBP3 ARHGAP17 ASAP1 SYNGAP1 ASAP2 ARAP1	8.54e-04	279	109	7	GO:0005096
GeneOntologyMolecularFunction	protein domain specific binding	ESPN PDCD6IP WIPF1 ARHGAP17 TACC2 CBLB SYNGAP1 SCAF1 FMN1 CASKIN1 ZBTB21 ROBO1 SON	9.63e-04	875	109	13	GO:0019904
GeneOntologyBiologicalProcess	axon midline choice point recognition	ROBO1 ROBO3 FOXG1	4.55e-06	7	106	3	GO:0016199
GeneOntologyBiologicalProcess	axon choice point recognition	ROBO1 ROBO3 FOXG1	1.08e-05	9	106	3	GO:0016198
Domain	WH2	ESPN WIPF1 WASHC1 INF2 WASH2P	2.40e-07	24	109	5	PS51082
Domain	WH2_dom	ESPN WIPF1 INF2 WASH2P	6.09e-06	21	109	4	IPR003124
Domain	WH2	ESPN WIPF1 INF2	6.72e-05	14	109	3	SM00246
Domain	MYB_LIKE	SMARCA5 NCOR2 MYPOP MTA1	6.95e-05	38	109	4	PS50090
Domain	FH2	FMNL3 INF2 FMN1	8.36e-05	15	109	3	PS51444
Domain	FH2_Formin	FMNL3 INF2 FMN1	8.36e-05	15	109	3	IPR015425
Domain	FH2	FMNL3 INF2 FMN1	8.36e-05	15	109	3	PF02181
Domain	FH2	FMNL3 INF2 FMN1	8.36e-05	15	109	3	SM00498
Domain	Post-SET_dom	SETD1B NSD3 SETDB1	1.02e-04	16	109	3	IPR003616
Domain	PostSET	SETD1B NSD3 SETDB1	1.02e-04	16	109	3	SM00508
Domain	WH2	ESPN WIPF1 INF2	1.02e-04	16	109	3	PF02205
Domain	POST_SET	SETD1B NSD3 SETDB1	1.02e-04	16	109	3	PS50868
Domain	SANT	SMARCA5 NCOR2 MYPOP MTA1	2.06e-04	50	109	4	SM00717
Domain	SANT/Myb	SMARCA5 NCOR2 MYPOP MTA1	2.40e-04	52	109	4	IPR001005
Domain	PWWP	NSD3 PWWP2A MBD5	3.15e-04	23	109	3	PF00855
Domain	PWWP_dom	NSD3 PWWP2A MBD5	3.15e-04	23	109	3	IPR000313
Domain	PWWP	NSD3 PWWP2A MBD5	3.58e-04	24	109	3	PS50812
Domain	PH	RAPH1 ARHGEF5 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	3.93e-04	229	109	7	PF00169
Domain	SANT_dom	SMARCA5 NCOR2 MTA1	4.56e-04	26	109	3	IPR017884
Domain	ZF_FCS	SOBP PHC1	4.99e-04	6	109	2	PS51024
Domain	SANT	SMARCA5 NCOR2 MTA1	5.70e-04	28	109	3	PS51293
Domain	ArfGap	ASAP1 ASAP2 ARAP1	6.33e-04	29	109	3	SM00105
Domain	ZnF_U1	ZFHX4 ZFHX2 ZFHX3	6.33e-04	29	109	3	SM00451
Domain	Znf_U1	ZFHX4 ZFHX2 ZFHX3	6.33e-04	29	109	3	IPR003604
Domain	ArfGap	ASAP1 ASAP2 ARAP1	6.33e-04	29	109	3	PF01412
Domain	ARFGAP	ASAP1 ASAP2 ARAP1	6.33e-04	29	109	3	PS50115
Domain	ArfGAP	ASAP1 ASAP2 ARAP1	6.33e-04	29	109	3	IPR001164
Domain	Znf_MYM	PHC1 ZMYM3	6.95e-04	7	109	2	IPR010507
Domain	zf-FCS	PHC1 ZMYM3	6.95e-04	7	109	2	PF06467
Domain	-	ARHGAP17 ASAP1 ASAP2	7.00e-04	30	109	3	1.20.1270.60
Domain	AH/BAR-dom	ARHGAP17 ASAP1 ASAP2	7.00e-04	30	109	3	IPR027267
Domain	Homeodomain-like	SMARCA5 UNCX NCOR2 MYPOP MTA1 ZFHX4 ZFHX2 ZFHX3	7.34e-04	332	109	8	IPR009057
Domain	Myb_DNA-binding	SMARCA5 NCOR2 MTA1	1.10e-03	35	109	3	PF00249
Domain	Drf_GBD	FMNL3 INF2	1.18e-03	9	109	2	PF06371
Domain	FH3_dom	FMNL3 INF2	1.18e-03	9	109	2	IPR010472
Domain	GTPase-bd	FMNL3 INF2	1.18e-03	9	109	2	IPR010473
Domain	Drf_FH3	FMNL3 INF2	1.18e-03	9	109	2	PF06367
Domain	Drf_FH3	FMNL3 INF2	1.18e-03	9	109	2	SM01139
Domain	Drf_GBD	FMNL3 INF2	1.18e-03	9	109	2	SM01140
Domain	PH	RAPH1 ARHGEF5 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	1.23e-03	278	109	7	SM00233
Domain	PH_DOMAIN	RAPH1 ARHGEF5 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	1.25e-03	279	109	7	PS50003
Domain	PH_domain	RAPH1 ARHGEF5 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	1.28e-03	280	109	7	IPR001849
Domain	RA	RIN3 RAPH1 ARAP1	1.30e-03	37	109	3	PS50200
Domain	-	SMARCA5 UNCX NCOR2 MYPOP ZFHX4 ZFHX2 ZFHX3	1.36e-03	283	109	7	1.10.10.60
Domain	RA_dom	RIN3 RAPH1 ARAP1	1.63e-03	40	109	3	IPR000159
Domain	SH3	ARHGEF5 ASAP1 PRAM1 ASAP2 CASKIN1 SH3D19	1.68e-03	216	109	6	SM00326
Domain	SH3	ARHGEF5 ASAP1 PRAM1 ASAP2 CASKIN1 SH3D19	1.68e-03	216	109	6	PS50002
Domain	SET	SETD1B NSD3 SETDB1	1.75e-03	41	109	3	PF00856
Domain	GBD/FH3_dom	FMNL3 INF2	1.79e-03	11	109	2	IPR014768
Domain	Methyl_CpG_DNA-bd	SETDB1 MBD5	1.79e-03	11	109	2	IPR001739
Domain	MBD	SETDB1 MBD5	1.79e-03	11	109	2	PF01429
Domain	DNA-bd_dom	SETDB1 MBD5	1.79e-03	11	109	2	IPR016177
Domain	GBD_FH3	FMNL3 INF2	1.79e-03	11	109	2	PS51232
Domain	MBD	SETDB1 MBD5	1.79e-03	11	109	2	SM00391
Domain	MBD	SETDB1 MBD5	1.79e-03	11	109	2	PS50982
Domain	SH3_domain	ARHGEF5 ASAP1 PRAM1 ASAP2 CASKIN1 SH3D19	1.84e-03	220	109	6	IPR001452
Domain	-	RAPH1 ARHGEF5 RANBP3 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	2.08e-03	391	109	8	2.30.29.30
Domain	SET	SETD1B NSD3 SETDB1	2.45e-03	46	109	3	SM00317
Domain	NPIP	NPIPB8 NPIPB6	2.93e-03	14	109	2	IPR009443
Domain	SET_dom	SETD1B NSD3 SETDB1	3.10e-03	50	109	3	IPR001214
Domain	SET	SETD1B NSD3 SETDB1	3.10e-03	50	109	3	PS50280
Domain	PH_dom-like	RAPH1 ARHGEF5 RANBP3 ASAP1 SYNGAP1 ASAP2 ARAP1 SOS2	3.51e-03	426	109	8	IPR011993
Domain	Ankyrin_rpt	ESPN RAPH1 ASAP1 ASAP2 CASKIN1 ANKRD34A	4.37e-03	262	109	6	IPR002110
Pathway	BIOCARTA_ARAP_PATHWAY	ASAP1 ASAP2 ARAP1	6.96e-05	17	68	3	M2482
Pathway	WP_RETT_SYNDROME	SYNGAP1 NCOR2 RHOBTB2 FOXG1	8.21e-05	48	68	4	M39759
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CCDC71L TFEB RIN3 SETD1B ZNF628 CDK12 MEX3D UBR4 THAP8 ARHGAP17 CC2D1A GRIN2D KDM6B BCL9 ZNF865 CHRM4 NSD3 C6orf132 PRR12 NHSL1 SCAF1 NCOR2 INF2 CASKIN1 ANKRD34A MLLT1 ZNF579 MBD5 ARAP1	2.54e-18	1105	115	29	35748872
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PDCD6IP ARHGEF5 RANBP3 UBR4 BCL9 ASAP1 C6orf132 SYNGAP1 NCOR2 ASAP2 MTA1 INAVA NYAP1 ARAP1 SON SOS2	1.11e-12	430	115	16	35044719
Pubmed	Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.	PDCD6IP WIPF1 RAPH1 ARHGAP17 CBLB ASAP1 SH3D19 PRRC2A ARAP1	1.02e-10	108	115	9	19531213
Pubmed	Characterization of the murine orthologue of a novel human subtelomeric multigene family.	WASHC1 WASH3P WASH4P WASH2P	5.66e-10	5	115	4	11701968
Pubmed	A human MAP kinase interactome.	PDCD6IP WIPF1 RBM33 ARHGAP17 CBLB ASAP1 NSD3 SETDB1 ASAP2 SH3D19 ROBO1 WASH2P MBD5 SOS2	8.84e-10	486	115	14	20936779
Pubmed	Human subtelomeric WASH genes encode a new subclass of the WASP family.	WASHC1 WASH3P WASH4P WASH2P	1.69e-09	6	115	4	18159949
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TFEB PDCD6IP RAPH1 ARHGEF5 RANBP3 MAZ MAP3K14 ARHGAP17 CC2D1A MYLK2 MEX3C NSD3 C6orf132 NHSL1 SH3D19 ZBTB21 CAMSAP2	3.81e-09	861	115	17	36931259
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SMARCA5 MAZ SRPK2 NSD3 CCNT1 SCAF1 NCOR2 SETDB1 MTA1 FBN2 ZFHX4 ZBTB21 MLLT1 ZFHX3 ABHD8 ZNF579 ZMYM3 SON ALG13	4.73e-09	1116	115	19	31753913
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	RBM33 CDK12 MAZ SRPK2 ZFC3H1 MYLK2 NSD3 C6orf132 PRR12 PWWP2A CCNT1 SCAF1 MTA1 PPP1R18 MLLT1 ZFHX3 ZNF579 CAMSAP2 PRRC2A ZMYM3 SON	1.96e-08	1497	115	21	31527615
Pubmed	CIN85 interacting proteins in B cells-specific role for SHIP-1.	PDCD6IP WIPF1 ARHGAP17 CBLB ASAP1 ARAP1	2.60e-08	54	115	6	21725061
Pubmed	Human transcription factor protein interaction networks.	SMARCA5 RBM33 SOBP MAZ UBR4 CC2D1A BCL9 PRR12 NCOR2 SETDB1 MTA1 FBN2 ZFHX4 ZBTB21 MLLT1 ZFHX3 PRRC2A MNT ZMYM3 VCL	4.63e-08	1429	115	20	35140242
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX4 ZFHX2 ZFHX3	1.41e-07	4	115	3	23300874
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TFEB SMARCA5 CHERP MED9 MAZ ZFC3H1 NSD3 PRR12 PWWP2A SCAF1 NCOR2 MYPOP MTA1 MLLT1 MNT SF3B2 ZMYM3 SON	2.59e-07	1294	115	18	30804502
Pubmed	KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.	CHERP RBM33 UBR4 TACC2 NCOR2 SF3B2 SON	2.71e-07	130	115	7	35545047
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SMARCA5 RAPH1 CDK12 BCL9 SCAF1 NCOR2 MTA1 ZBTB21 PPP1R18 ZNF579 PRRC2A SF3B2 ZMYM3 SON	2.91e-07	774	115	14	15302935
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	SMARCA5 CHERP RAPH1 CDK12 RANBP3 CC2D1A TACC2 CCNT1 SH3D19 ZBTB21 CAMSAP2 PRRC2A SF3B2 VCL SON	4.81e-07	934	115	15	33916271
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	CHERP CDK12 PCLO UBR4 ZNF865 PHC1 PRAM1 NCOR2 MYPOP MTA1	8.43e-07	396	115	10	26687479
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	RIN3 PDCD6IP RETREG2 SOBP UBR4 MAP3K14 CC2D1A KDM6B CBLB SETDB1 INF2 ZNF580 WASH2P ZNF579 SF3B2 ARAP1	9.51e-07	1124	115	16	21900206
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	SMARCA5 CHERP RAPH1 RBM33 CDK12 CCNT1 MTA1 INF2 SF3B2 VCL SON	1.01e-06	506	115	11	30890647
Pubmed	CIN85, a Cbl-interacting protein, is a component of AMAP1-mediated breast cancer invasion machinery.	CBLB ASAP1 ASAP2	1.22e-06	7	115	3	17255943
Pubmed	Proteomics analysis of Ring1B/Rnf2 interactors identifies a novel complex with the Fbxl10/Jhdm1B histone demethylase and the Bcl6 interacting corepressor.	SMARCA5 PHC1 SETDB1 MTA1 MLLT1	1.32e-06	57	115	5	17296600
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAPH1 UBR4 PHC1 PRR12 NCOR2 SETDB1 ZFHX4 ZBTB21 ZFHX3 ZMYM3	1.37e-06	418	115	10	34709266
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TFEB RANBP3 SRPK2 TACC2 CCNT1 NCOR2 MTA1 SH3D19 ZFHX3 MBD5 PRRC2A	1.77e-06	536	115	11	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TFEB RANBP3 SRPK2 TACC2 CCNT1 NCOR2 MTA1 SH3D19 ZFHX3 MBD5 PRRC2A	1.83e-06	538	115	11	10512203
Pubmed	Differentially regulated and evolved genes in the fully sequenced Xq/Yq pseudoautosomal region.	WASHC1 WASH3P WASH2P	1.95e-06	8	115	3	10655549
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	SMARCA5 RAPH1 RBM33 ARHGEF5 MAZ ARHGAP17 ASAP1 CCNT1 ASAP2 MTA1 ROBO1 PRRC2A ARAP1 SOS2	2.12e-06	916	115	14	32203420
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RAPH1 CDK12 UBR4 SRPK2 ZFC3H1 SCAF1 ZFHX4 PRRC2A SON	3.39e-06	361	115	9	26167880
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SMARCA5 CHERP RBM33 CDK12 MAZ NSD3 CCNT1 PRAM1 NCOR2 MTA1 MLLT1 PRRC2A SF3B2 SON	3.39e-06	954	115	14	36373674
Pubmed	FBP WW domains and the Abl SH3 domain bind to a specific class of proline-rich ligands.	SRPK2 FMNL3 ZFHX3	4.16e-06	10	115	3	9171351
Pubmed	TRIP12 promotes small-molecule-induced degradation through K29/K48-branched ubiquitin chains.	SMARCA5 UBR4 NSD3 CCNT1	4.31e-06	33	115	4	33567268
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CCDC71L SMARCA5 ARHGEF5 MAZ PHC1 NSD3 PWWP2A CCNT1 MTA1 ZBTB21 ZMYM3	5.87e-06	608	115	11	36089195
Pubmed	A census of human transcription factors: function, expression and evolution.	TFEB UNCX FOSB MAZ THAP8 MYPOP ZFHX4 SKOR2 ZFHX2 MLLT1 ZFHX3 MNT FOXG1	1.01e-05	908	115	13	19274049
Pubmed	PWWP2A binds distinct chromatin moieties and interacts with an MTA1-specific core NuRD complex.	PWWP2A MTA1	1.08e-05	2	115	2	30327463
Pubmed	SETDB1 mediated FosB expression increases the cell proliferation rate during anticancer drug therapy.	FOSB SETDB1	1.08e-05	2	115	2	26949019
Pubmed	WASH and the Arp2/3 complex regulate endosome shape and trafficking.	WASHC1 WASH3P	1.08e-05	2	115	2	20175130
Pubmed	The mouse ZFH-4 protein contains four homeodomains and twenty-two zinc fingers.	ZFHX4 ZFHX3	1.08e-05	2	115	2	10873665
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	CHERP RBM33 WASHC1 PRR22 TACC2 BCL9 PHC1 SYNGAP1 PWWP2A NCOR2 FBN2 SLC16A2 ZNF579 ROBO3 MNT	1.18e-05	1215	115	15	15146197
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	SMARCA5 ZNF628 MAZ FMNL3 NCOR2 MTA1 ZFHX4 PRRC2A	1.21e-05	321	115	8	32098917
Pubmed	Expression of multiple formins in adult tissues and during developmental stages of mouse brain.	FMNL3 INF2 FMN1	1.25e-05	14	115	3	26272686
Pubmed	Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains.	SRPK2 FMNL3 FMN1	1.25e-05	14	115	3	8605874
Pubmed	Floor-plate-derived netrin-1 is dispensable for commissural axon guidance.	ROBO1 ROBO3 FOXG1	1.25e-05	14	115	3	28445456
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	SMARCA5 PDCD6IP MED9 SRPK2 MEX3C CCNT1 NCOR2 INF2 MLLT1 INAVA POLD3 CAMSAP2 PRRC2A SF3B2 VCL	1.60e-05	1247	115	15	27684187
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	WIPF1 UNCX RBM33 CC2D1A BCL9 PRR12 CCNT1 PRAM1 NCOR2 MTA1 ZBTB21 PRRC2A MNT ZMYM3	1.74e-05	1103	115	14	34189442
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	PDCD6IP UBR4 SRPK2 GRIN2D BCL9 SYNGAP1 NCOR2 CASKIN1 SH3D19 ZBTB21 CAMSAP2 PRRC2A FOXG1	1.88e-05	963	115	13	28671696
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	RAPH1 CC2D1A ASAP1 C6orf132 NHSL1 FMN1 SH3D19 PPP1R18 INAVA VCL	1.92e-05	565	115	10	25468996
Pubmed	The protein interaction landscape of the human CMGC kinase group.	TFEB CHERP PDCD6IP CDK12 MED9 MAZ SRPK2 CCNT1 FAM222A MLLT1 SON	2.04e-05	695	115	11	23602568
Pubmed	Interaction network of human early embryonic transcription factors.	SMARCA5 SOBP BCL9 PRR12 NCOR2 ZFHX4 ZFHX3 ZMYM3	2.30e-05	351	115	8	38297188
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	SMARCA5 MTA1 ZFHX4 ZFHX3 ZMYM3	2.45e-05	103	115	5	32744500
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	WIPF1 CBLB ASAP1 ASAP2 SOS2	2.45e-05	103	115	5	21706016
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SMARCA5 CHERP MAZ ZNF865 MTA1 ZFHX4 ZBTB21 ZFHX3 SF3B2 SON	2.50e-05	583	115	10	29844126
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	SMARCA5 CHERP SRPK2 ZFC3H1 CBLB NSD3 PRR12 CCNT1 PRRC2A SF3B2 ZMYM3 SON	2.51e-05	847	115	12	35850772
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SMARCA5 MEX3D SRPK2 ASAP1 MEX3C SCAF1 ROBO1 SON	2.65e-05	358	115	8	32460013
Pubmed	Functional proteomics mapping of a human signaling pathway.	PDCD6IP CDK12 UBR4 CBLB FMNL3 NCOR2 SETDB1 FBN2 VCL SON	2.81e-05	591	115	10	15231748
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	SMARCA5 FOSB UBR4 SRPK2 NCOR2 MTA1 ZFHX4 ZBTB21 MNT SF3B2 FOXG1 ZMYM3	2.81e-05	857	115	12	25609649
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	SETD1B UBR4 WASHC1 PRR12 NCOR2 WASH3P FMN1 CASKIN1 PRRC2A	3.00e-05	475	115	9	31040226
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHERP RBM33 RANBP3 BCL9 PRR12 CCNT1 ZBTB21	3.22e-05	268	115	7	33640491
Pubmed	Robo family of proteins exhibit differential expression in mouse spinal cord and Robo-Slit interaction is required for midline crossing in vertebrate spinal cord.	ROBO1 ROBO3	3.24e-05	3	115	2	15768400
Pubmed	Rig-1 a new member of Robo family genes exhibits distinct pattern of expression during mouse development.	ROBO1 ROBO3	3.24e-05	3	115	2	14678835
Pubmed	Changes in bile acid composition are correlated with reduced intestinal cholesterol uptake in intestine-specific WASH-deficient mice.	WASHC1 WASH3P	3.24e-05	3	115	2	38086439
Pubmed	Alternative splicing of the Robo3 axon guidance receptor governs the midline switch from attraction to repulsion.	ROBO1 ROBO3	3.24e-05	3	115	2	18466743
Pubmed	WASH Regulates Glucose Homeostasis by Facilitating Glut2 Receptor Recycling in Pancreatic β-Cells.	WASHC1 WASH3P	3.24e-05	3	115	2	30425062
Pubmed	ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state.	MTA1 ZFHX4	3.24e-05	3	115	2	24440720
Pubmed	WASH is required for the differentiation commitment of hematopoietic stem cells in a c-Myc-dependent manner.	WASHC1 WASH3P	3.24e-05	3	115	2	25225459
Pubmed	The histone demethylase Kdm6b regulates subtype diversification of mouse spinal motor neurons during development.	KDM6B ZFHX4 ZFHX3	3.85e-05	20	115	3	35177643
Pubmed	FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.	SETD1B NCOR2 MTA1	3.85e-05	20	115	3	27773593
Pubmed	Corepressor SMRT is required to maintain Hox transcriptional memory during somitogenesis.	UNCX KDM6B NCOR2	4.48e-05	21	115	3	30254164
Pubmed	Snf2h Drives Chromatin Remodeling to Prime Upper Layer Cortical Neuron Development.	SMARCA5 FOXG1 VCL	4.48e-05	21	115	3	31680852
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	SMARCA5 RBM33 CDK12 RANBP3 CCNT1 ZFHX3 SF3B2	4.54e-05	283	115	7	30585729
Pubmed	Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.	PDCD6IP CC2D1A CBLB SH3D19	4.79e-05	60	115	4	34761192
Pubmed	WASH knockout T cells demonstrate defective receptor trafficking, proliferation, and effector function.	WASHC1 WASH3P	6.48e-05	4	115	2	23275443
Pubmed	The mouse ADP-ribosylation factor-like 4 gene: two separate promoters direct specific transcription in tissues and testicular germ cell.	FOXG1 SOS2	6.48e-05	4	115	2	9761722
Pubmed	Inactivation of Rho GTPases by Burkholderia cenocepacia Induces a WASH-Mediated Actin Polymerization that Delays Phagosome Maturation.	WASHC1 WASH3P	6.48e-05	4	115	2	32492429
Pubmed	Evidence for the existence of two Robo3 isoforms with divergent biochemical properties.	ROBO1 ROBO3	6.48e-05	4	115	2	16226035
Pubmed	The hepatic WASH complex is required for efficient plasma LDL and HDL cholesterol clearance.	WASHC1 WASH3P	6.48e-05	4	115	2	31167970
Pubmed	Loss of MAGEL2 in Prader-Willi syndrome leads to decreased secretory granule and neuropeptide production.	WASHC1 WASH3P	6.48e-05	4	115	2	32879135
Pubmed	The expanding role of MBD genes in autism: identification of a MECP2 duplication and novel alterations in MBD5, MBD6, and SETDB1.	SETDB1 MBD5	6.48e-05	4	115	2	23055267
Pubmed	Trafficking defects in WASH-knockout fibroblasts originate from collapsed endosomal and lysosomal networks.	WASHC1 WASH3P	6.48e-05	4	115	2	22718907
Pubmed	TGF-β1 signaling targets metastasis-associated protein 1, a new effector in epithelial cells.	FOSB MTA1	6.48e-05	4	115	2	21258411
Pubmed	A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.	PWWP2A MTA1	6.48e-05	4	115	2	30228260
Pubmed	Interaction of POB1, a downstream molecule of small G protein Ral, with PAG2, a paxillin-binding protein, is involved in cell migration.	ASAP1 ASAP2	6.48e-05	4	115	2	12149250
Pubmed	Crucial roles of Robo proteins in midline crossing of cerebellofugal axons and lack of their up-regulation after midline crossing.	ROBO1 ROBO3	6.48e-05	4	115	2	18986510
Pubmed	Genetic analyses of roundabout (ROBO) axon guidance receptors in autism.	ROBO1 ROBO3	6.48e-05	4	115	2	18270976
Pubmed	NOTCH4 potentiates the IL-13 induced genetic program in M2 alternative macrophages through the AP1 and IRF4-JMJD3 axis.	FOSB KDM6B	6.48e-05	4	115	2	37478314
Pubmed	Dendritic cells utilize the evolutionarily conserved WASH and retromer complexes to promote MHCII recycling and helper T cell priming.	WASHC1 WASH3P	6.48e-05	4	115	2	24886983
Pubmed	Expression of the histone lysine methyltransferases SETD1B, SETDB1, SETD2, and CFP1 exhibits significant changes in the oocytes and granulosa cells of aged mouse ovaries.	SETD1B SETDB1	6.48e-05	4	115	2	35445296
Pubmed	HIV-1 Tat recruits transcription elongation factors dispersed along a flexible AFF4 scaffold.	CCNT1 MLLT1	6.48e-05	4	115	2	23251033
Pubmed	Expression patterns of Slit and Robo family members during vertebrate limb development.	ROBO1 ROBO3	6.48e-05	4	115	2	11472852
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	SMARCA5 MAZ PHC1 NCOR2 MTA1 ZBTB21 ZMYM3 SON	6.99e-05	411	115	8	35182466
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	CHERP RBM33 MEX3D MAZ SRPK2 MEX3C ZNF579 PRRC2A SF3B2 SON ALG13	7.82e-05	807	115	11	22681889
Pubmed	Characterization of a novel Lbx1 mouse loss of function strain.	UNCX SLC15A2 ROBO3	8.66e-05	26	115	3	34906895
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	RBM33 CDK12 PCLO MAZ ARHGAP17 BCL9 PRR12 VCL	8.81e-05	425	115	8	24999758
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	PCLO MEX3D CBLB SYNGAP1 NHSL1 NYAP1	9.02e-05	218	115	6	33378226
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	SMARCA5 RAPH1 CDK12 RANBP3 CC2D1A NSD3 SH3D19 PRRC2A VCL	9.11e-05	549	115	9	38280479
Pubmed	TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.	SMARCA5 NCOR2 MTA1 ZFHX3 SF3B2 SON	9.49e-05	220	115	6	35785414
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	UBR4 WASHC1 PHC1 NSD3 NHSL1 INF2 SKOR2 ZBTB21 ZNF579 MBD5	1.01e-04	689	115	10	36543142
Pubmed	The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons.	ROBO1 ROBO3	1.08e-04	5	115	2	15084255
Pubmed	Identification and characterization of EBP, a novel EEN binding protein that inhibits Ras signaling and is recruited into the nucleus by the MLL-EEN fusion protein.	SH3D19 SOS2	1.08e-04	5	115	2	14551139
Pubmed	Endosomal WASH and exocyst complexes control exocytosis of MT1-MMP at invadopodia.	WASHC1 WASH3P	1.08e-04	5	115	2	24344185
Pubmed	Regulation of axon guidance by compartmentalized nonsense-mediated mRNA decay.	ROBO1 ROBO3	1.08e-04	5	115	2	23746841
Pubmed	Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells.	CDK12 CCNT1	1.08e-04	5	115	2	22547058
Interaction	TOP3B interactions	CCDC71L TFEB RIN3 SETD1B ZNF628 PDCD6IP RBM33 CDK12 MEX3D UBR4 THAP8 ARHGAP17 CC2D1A GRIN2D KDM6B BCL9 ZNF865 CHRM4 NSD3 C6orf132 PRR12 NHSL1 SCAF1 NCOR2 INF2 CASKIN1 ANKRD34A MLLT1 ZNF579 MBD5 PRRC2A ARAP1	5.96e-12	1470	110	32	int:TOP3B
Interaction	NCK2 interactions	WIPF1 RAPH1 FOSB ZC2HC1B SRPK2 CBLB ASAP1 SYNGAP1 NHSL1 ASAP2 MYPOP PRRC2A MNT ARAP1	1.68e-10	262	110	14	int:NCK2
Interaction	PRPF40A interactions	SMARCA5 CHERP WIPF1 CDK12 UBR4 SRPK2 FMNL3 CCNT1 FMN1 ZFHX3 SF3B2 VCL SON ALG13	1.46e-07	446	110	14	int:PRPF40A
Interaction	SH3KBP1 interactions	RIN3 PDCD6IP WIPF1 RAPH1 ARHGAP17 CBLB ASAP1 SYNGAP1 ASAP2 SH3D19 PRRC2A ARAP1	1.55e-07	315	110	12	int:SH3KBP1
Interaction	GRB2 interactions	RIN3 PDCD6IP WIPF1 RBM33 ARHGEF5 UBR4 ARHGAP17 PRR22 CBLB CHRM4 ASAP1 ASAP2 MTA1 SH3D19 PRRC2A SF3B2 ARAP1 SOS2	3.56e-07	806	110	18	int:GRB2
Interaction	PFN1 interactions	RAPH1 PCLO ARHGAP17 SRPK2 C6orf132 NHSL1 CCNT1 MYPOP INF2 SH3D19 MLLT1 SF3B2 VCL ALG13	7.19e-07	509	110	14	int:PFN1
Interaction	FOXK2 interactions	RIN3 SMARCA5 SETD1B UBR4 SRPK2 NCOR2 MTA1 INF2 MNT	4.02e-06	225	110	9	int:FOXK2
Interaction	NCK1 interactions	SMARCA5 WIPF1 UBR4 CBLB ASAP1 NHSL1 ASAP2 ARAP1 SOS2	7.74e-06	244	110	9	int:NCK1
Interaction	H3-3A interactions	CCDC71L SMARCA5 SETD1B ARHGEF5 FOSB MAZ KDM6B MYLK2 NSD3 PWWP2A CCNT1 MTA1 ZBTB21 SF3B2 ZMYM3	1.37e-05	749	110	15	int:H3-3A
Interaction	SOX6 interactions	RBM33 SOBP NCOR2 MTA1 ZFHX4 ZFHX3 PRRC2A	2.48e-05	157	110	7	int:SOX6
Interaction	YWHAH interactions	TFEB RIN3 PDCD6IP ARHGEF5 RANBP3 MEX3D MAZ ARHGAP17 CC2D1A MEX3C NSD3 C6orf132 SYNGAP1 NHSL1 SH3D19 ZBTB21 CAMSAP2 VCL	2.78e-05	1102	110	18	int:YWHAH
Interaction	CACNG2 interactions	WIPF1 SRPK2 SYNGAP1 CCNT1	3.04e-05	33	110	4	int:CACNG2
Interaction	VASP interactions	RAPH1 UBR4 C6orf132 NHSL1 INF2 CAMSAP2 SF3B2 VCL ALG13	3.39e-05	294	110	9	int:VASP
Interaction	ARHGAP12 interactions	RAPH1 SRPK2 ASAP1 PRR12 ASAP2	3.51e-05	68	110	5	int:ARHGAP12
Interaction	CRK interactions	RIN3 ARHGEF5 ARHGAP17 MAGEC3 CBLB ASAP1 SYNGAP1 INF2 ARAP1 SOS2	3.55e-05	370	110	10	int:CRK
Interaction	FMR1 interactions	UBR4 SRPK2 TACC2 BCL9 SYNGAP1 NCOR2 CASKIN1 INAVA CAMSAP2 PRRC2A SF3B2 ALG13	3.66e-05	536	110	12	int:FMR1
Interaction	YWHAG interactions	TFEB PDCD6IP RAPH1 CDK12 ARHGEF5 RANBP3 MAZ ARHGAP17 MYLK2 C6orf132 SYNGAP1 NHSL1 SH3D19 ZBTB21 ANKRD34A CAMSAP2 ZMYM3 VCL SON	4.25e-05	1248	110	19	int:YWHAG
Interaction	SNRNP40 interactions	ESPN CHERP CDK12 SRPK2 ZFC3H1 BCL9 NSD3 SCAF1 NCOR2 MTA1 ZBTB21 ZFHX3 SON	4.43e-05	637	110	13	int:SNRNP40
Interaction	PTK2B interactions	PDCD6IP CBLB ASAP1 SYNGAP1 ASAP2 ZFHX2	4.85e-05	119	110	6	int:PTK2B
Interaction	PAX9 interactions	BCL9 PRR12 NCOR2 ZFHX4 ZFHX3 ZNF580	7.94e-05	130	110	6	int:PAX9
Interaction	PAX2 interactions	BCL9 NSD3 PRR12 NCOR2 ZFHX4	1.02e-04	85	110	5	int:PAX2
Interaction	SRGAP2 interactions	WIPF1 KDM6B SYNGAP1 ZBTB21 ANKRD34A ROBO1 CAMSAP2	1.04e-04	197	110	7	int:SRGAP2
Interaction	ACTC1 interactions	SMARCA5 CHERP PDCD6IP WIPF1 RAPH1 RBM33 CDK12 CCNT1 MTA1 INF2 SF3B2 VCL SON	1.05e-04	694	110	13	int:ACTC1
Interaction	H2BC21 interactions	RIN3 SMARCA5 MED9 PCLO KDM6B PHC1 NSD3 PRR12 PWWP2A MTA1 MLLT1 PRRC2A ZMYM3	1.08e-04	696	110	13	int:H2BC21
Interaction	GSC interactions	BCL9 PRR12 NCOR2 ZFHX4 ZFHX3	1.14e-04	87	110	5	int:GSC
Interaction	FOXQ1 interactions	SMARCA5 SRPK2 NCOR2 ZFHX4 SF3B2 ZMYM3	1.24e-04	141	110	6	int:FOXQ1
Interaction	PRMT2 interactions	ESPN SETD1B KDM6B CBLB PRRC2A	1.42e-04	91	110	5	int:PRMT2
Interaction	WASH4P interactions	WASH3P WASH4P	1.76e-04	4	110	2	int:WASH4P
Interaction	KDM1A interactions	SMARCA5 RAPH1 UBR4 PHC1 PRR12 NCOR2 SETDB1 MTA1 ZFHX4 SH3D19 ZBTB21 ZFHX3 SF3B2 FOXG1 ZMYM3	1.81e-04	941	110	15	int:KDM1A
Interaction	TLX3 interactions	FOSB BCL9 SYNGAP1 PRR12 NCOR2 ZFHX4 SLC15A2 ZFHX3	1.97e-04	291	110	8	int:TLX3
Interaction	TLE3 interactions	CHERP CDK12 BCL9 PRR12 NCOR2 ZFHX3 FOXG1 SON ALG13	2.20e-04	376	110	9	int:TLE3
Interaction	ERG interactions	UBR4 BCL9 PRR12 NCOR2 SETDB1 ZFHX4 SF3B2	2.24e-04	223	110	7	int:ERG
Interaction	CRKL interactions	RIN3 WIPF1 ARHGEF5 KDM6B CBLB ASAP1 SOS2	2.50e-04	227	110	7	int:CRKL
Interaction	SP7 interactions	RBM33 BCL9 CBLB PRR12 NCOR2 FBN2 ZFHX4 MLLT1	2.65e-04	304	110	8	int:SP7
Interaction	NAA40 interactions	SMARCA5 CHERP RAPH1 CDK12 RANBP3 CC2D1A TACC2 CCNT1 SH3D19 ZBTB21 CAMSAP2 PRRC2A SF3B2 VCL SON	2.75e-04	978	110	15	int:NAA40
Interaction	SH3RF1 interactions	PDCD6IP WIPF1 CBLB PRAM1 SH3D19	3.15e-04	108	110	5	int:SH3RF1
Interaction	WBP4 interactions	CHERP SETD1B WIPF1 FMN1 SF3B2	3.29e-04	109	110	5	int:WBP4
Interaction	POU5F1 interactions	TFEB SMARCA5 UBR4 ZNF865 PHC1 PRAM1 NCOR2 SETDB1 MYPOP MTA1 ZFHX3	3.51e-04	584	110	11	int:POU5F1
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	CHERP RANBP3 MEX3D TGFBR3L CC2D1A PRR22 JSRP1 PRAM1 MLLT1 ABHD8	3.40e-05	797	115	10	chr19p13
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	IL11 ZNF628 FOSB THAP8 GRIN2D ZNF865 PRR12 SCAF1 MYPOP C19orf85 ZNF580 ZNF579	4.70e-05	1192	115	12	chr19q13
Cytoband	19q13.42	ZNF628 ZNF865 ZNF580 ZNF579	2.87e-04	125	115	4	19q13.42
Cytoband	19p13.3	RANBP3 MEX3D PRR22 JSRP1 MLLT1	3.40e-04	237	115	5	19p13.3
Cytoband	19q13.3-q13.4	IL11 SCAF1	4.77e-04	13	115	2	19q13.3-q13.4
GeneFamily	Wiskott-Aldrich Syndrome protein family	WASHC1 WASH3P WASH4P WASH2P	5.05e-07	16	76	4	14
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX4 ZFHX2 ZFHX3	3.13e-05	15	76	3	529
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	SMARCA5 NCOR2 MYPOP MTA1	7.22e-05	53	76	4	532
GeneFamily	PWWP domain containing	NSD3 PWWP2A MBD5	1.04e-04	22	76	3	1147
GeneFamily	ArfGAPs	ASAP1 ASAP2 ARAP1	3.56e-04	33	76	3	395
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1B NSD3 SETDB1	3.89e-04	34	76	3	487
GeneFamily	Ankyrin repeat domain containing	ESPN ASAP1 ASAP2 CASKIN1 ANKRD34A ARAP1	5.41e-04	242	76	6	403
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	SETDB1 MBD5	9.36e-04	11	76	2	1025
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RAPH1 ASAP1 ASAP2 ARAP1 SOS2	1.75e-03	206	76	5	682
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO ZFC3H1	1.77e-03	15	76	2	26
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	ASAP1 ASAP2	2.28e-03	17	76	2	1291
GeneFamily	G-patch domain containing\|Minor histocompatibility antigens	CHERP SON	3.81e-03	22	76	2	579
GeneFamily	Sterile alpha motif domain containing	PHC1 CASKIN1 ARAP1	6.06e-03	88	76	3	760
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PCLO CC2D1A	1.00e-02	36	76	2	823
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF628 MAZ ZNF865 ZBTB21 ZFHX2 ZFHX3 ZNF580 ZNF579	1.04e-02	718	76	8	28
GeneFamily	Tudor domain containing	SETDB1 ALG13	1.06e-02	37	76	2	780
Coexpression	GSE34179_THPOK_KO_VS_WT_VA14I_NKTCELL_UP	TFEB PDCD6IP RAPH1 PRR22 TACC2 ZNF865 PTPN5 ZNF579	2.75e-06	200	114	8	M9397
Coexpression	GINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN	RBM33 RANBP3 ARHGAP17 SCAF1 SETDB1 WASH3P MYPOP ZNF580 PRRC2A	1.75e-05	338	114	9	M17094
Coexpression	LAKE_ADULT_KIDNEY_C25_ENDOTHELIAL_CELLS_UNASSIGNED	SRPK2 ZFC3H1 ASAP1 ZFHX3	2.23e-05	38	114	4	M39244
Coexpression	GSE9988_LPS_VS_CTRL_TREATED_MONOCYTE_DN	TFEB SETD1B RETREG2 MAP3K14 MNT SF3B2 ARAP1	2.80e-05	200	114	7	M5859
Coexpression	GSE22886_NAIVE_BCELL_VS_BLOOD_PLASMA_CELL_UP	SOBP KDM6B CBLB PHC1 ASAP1 MNT SOS2	2.80e-05	200	114	7	M4440
Coexpression	PICCALUGA_ANGIOIMMUNOBLASTIC_LYMPHOMA_DN	WIPF1 FOSB ZFC3H1 KDM6B MEX3C SON	3.07e-05	137	114	6	M4781
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500	CHERP SETD1B WIPF1 ASAP2 FBN2 ZFHX4 ROBO1 ZFHX3 SON	6.48e-06	249	111	9	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#5_top-relative-expression-ranked_1000	SMARCA5 CHERP SETD1B WIPF1 ASAP2 FBN2 ZFHX4 ROBO1 ZFHX3 SON SOS2	4.19e-05	478	111	11	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k5
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 MAZ ZFC3H1 KDM6B NSD3 PPP1R18 SF3B2	4.12e-07	178	115	7	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	CHERP RAPH1 PRR22 ASAP2 INF2 INAVA	3.63e-06	159	115	6	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FOSB CBLB ASAP1 PTPN5 ROBO1 NYAP1	6.30e-06	175	115	6	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FOSB CBLB ASAP1 PTPN5 ROBO1 NYAP1	6.30e-06	175	115	6	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SETD1B ZNF628 ARHGAP17 PHC1 MEX3C SLC15A2	7.40e-06	180	115	6	62511d76d24b836839c3dcc2bf30485ffe9401e2
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11 MAZ KDM6B NCOR2 INAVA PRRC2A	8.92e-06	186	115	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMARCA5 CDK12 FOSB KDM6B NSD3 SON	9.19e-06	187	115	6	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL11 MAZ KDM6B NCOR2 INAVA PRRC2A	9.77e-06	189	115	6	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FOSB UBR4 MAP3K14 ZFC3H1 ZBTB21 VCL	1.07e-05	192	115	6	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Npw\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ESPN JSRP1 KCNK4 ZFHX4 ROBO3	1.13e-05	113	115	5	165de4316059222f33d1e51aeff4554037c0b937
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	SOBP CBLB ASAP2 SH3D19 ROBO1 ZFHX3	1.13e-05	194	115	6	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	SETD1B SOBP CBLB ROBO1 ROBO3 SOAT2	1.35e-05	200	115	6	332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_A2\|343B / Donor, Lineage, Cell class and subclass (all cells)	SETD1B ZNF628 PHC1 MEX3C SLC15A2	2.48e-05	133	115	5	8ff1cf0ea1fc33fe8384c0e65c1ee1853b25a2ae
Computational	Genes in the cancer module 198.	MAZ SRPK2 BCL9 CCNT1 SETDB1 ASAP2 MTA1 FOXG1	2.60e-04	303	60	8	MODULE_198
Computational	Genes in the cancer module 98.	MAZ SRPK2 BCL9 CCNT1 SETDB1 ASAP2 MTA1 FOXG1 SON	3.01e-04	393	60	9	MODULE_98
Drug	Adrenosterone [382-45-6]; Down 200; 13.4uM; HL60; HT_HG-U133A	TFEB RANBP3 UBR4 KDM6B NSD3 RHOBTB2 ZFHX3 CAMSAP2	5.83e-06	198	111	8	3107_DN
Drug	rotenone; Down 200; 1uM; MCF7; HT_HG-U133A	IL11 TFEB RETREG2 RANBP3 BCL9 NCOR2 RHOBTB2 ARAP1	5.83e-06	198	111	8	5915_DN
Disease	multiple sclerosis	ESPN SPEF2 MAZ MAP3K14 CBLB ASAP1 NCOR2 ASAP2 SLC15A2 ZFHX3 INAVA	1.30e-05	594	109	11	MONDO_0005301
Disease	pulse pressure measurement	CCDC71L RIN3 WIPF1 RAPH1 RBM33 KDM6B NSD3 FMNL3 ASAP2 FBN2 ZFHX4 ZFHX3 ROBO3 MBD5 VCL SOS2	5.23e-05	1392	109	16	EFO_0005763
Disease	Epilepsy, Cryptogenic	FOSB SYNGAP1 FOXG1 ALG13	2.47e-04	82	109	4	C0086237
Disease	Awakening Epilepsy	FOSB SYNGAP1 FOXG1 ALG13	2.47e-04	82	109	4	C0751111
Disease	Aura	FOSB SYNGAP1 FOXG1 ALG13	2.47e-04	82	109	4	C0236018
Disease	Intellectual Disability	GRIN2D KDM6B KCNK4 SYNGAP1 PRR12 RHOBTB2 FOXG1 ALG13	2.61e-04	447	109	8	C3714756
Disease	grapefruit juice consumption measurement	CCDC71L PCLO	2.81e-04	7	109	2	EFO_0010094
Disease	myoclonic-atonic epilepsy (implicated_via_orthology)	ROBO1 ROBO3	2.81e-04	7	109	2	DOID:0060475 (implicated_via_orthology)
Disease	breast cancer, ovarian carcinoma	RIN3 ARHGEF5 ABHD8	3.48e-04	37	109	3	EFO_0001075, MONDO_0007254
Disease	S-warfarin measurement	PTPN5 NHSL1 NCOR2 FMN1	4.69e-04	97	109	4	EFO_0803323
Disease	Epilepsy	FOSB SYNGAP1 FOXG1 ALG13	7.28e-04	109	109	4	C0014544
Disease	developmental disorder of mental health (implicated_via_orthology)	GRIN2D SYNGAP1 NCOR2	7.98e-04	49	109	3	DOID:0060037 (implicated_via_orthology)
Disease	metabolite measurement, body weight gain	TACC2 ZFHX3	8.71e-04	12	109	2	EFO_0004566, EFO_0004725
Disease	diffuse idiopathic skeletal hyperostosis	IL11 POLD3	1.38e-03	15	109	2	EFO_0007236
Disease	cortical surface area measurement	RIN3 RAPH1 MAP3K14 SRPK2 SMAD5-AS1 NHSL1 FBN2 ROBO1 ZFHX3 POLD3 PRRC2A FOXG1 SOS2	1.39e-03	1345	109	13	EFO_0010736
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Positive	FOSB ZFC3H1 ASAP1 MEX3C	1.44e-03	131	109	4	C4704862
Disease	Polyarthritis, Juvenile, Rheumatoid Factor Negative	FOSB ZFC3H1 ASAP1 MEX3C	1.44e-03	131	109	4	C4552091
Disease	Juvenile arthritis	FOSB ZFC3H1 ASAP1 MEX3C	1.44e-03	131	109	4	C3495559
Disease	Juvenile psoriatic arthritis	FOSB ZFC3H1 ASAP1 MEX3C	1.44e-03	131	109	4	C3714758
Disease	uterine prolapse	FBN2 POLD3	1.57e-03	16	109	2	EFO_1001864
Disease	Juvenile-Onset Still Disease	FOSB ZFC3H1 ASAP1 MEX3C	1.61e-03	135	109	4	C0087031
Disease	serum albumin measurement	TFEB RIN3 RAPH1 CDK12 MAP3K14 CBLB PRR12 SCAF1	1.62e-03	592	109	8	EFO_0004535
Disease	uric acid measurement	UNCX ARHGAP17 NSD3 ASAP2 SLC15A2 FMN1 ZMYM3 SOS2	1.95e-03	610	109	8	EFO_0004761
Disease	Major Depressive Disorder	IL11 RAPH1 PCLO CC2D1A BCL9	2.12e-03	243	109	5	C1269683
Disease	serum non-albumin protein measurement	NCOR2 MTA1 NPIPB6 PRRC2A ARAP1 SOS2	2.26e-03	361	109	6	EFO_0004568
Disease	atrial fibrillation	WIPF1 MEX3C NCOR2 ZFHX4 ZFHX3 MBD5	2.59e-03	371	109	6	EFO_0000275
Disease	Paroxysmal atrial fibrillation	WIPF1 MEX3C ZFHX3 MBD5	2.72e-03	156	109	4	C0235480
Disease	familial atrial fibrillation	WIPF1 MEX3C ZFHX3 MBD5	2.72e-03	156	109	4	C3468561
Disease	Persistent atrial fibrillation	WIPF1 MEX3C ZFHX3 MBD5	2.72e-03	156	109	4	C2585653
Disease	Unipolar Depression	IL11 RAPH1 PCLO CC2D1A BCL9	2.79e-03	259	109	5	C0041696
Disease	Primary familial hypertrophic cardiomyopathy	MYLK2 VCL	2.98e-03	22	109	2	cv:C0949658
Disease	pulse pressure measurement, alcohol consumption measurement	CCDC71L TACC2	2.98e-03	22	109	2	EFO_0005763, EFO_0007878
Disease	Atrial Fibrillation	WIPF1 MEX3C ZFHX3 MBD5	2.98e-03	160	109	4	C0004238
Disease	Diuretic use measurement	CCDC71L MEX3C FBN2 SOS2	3.62e-03	169	109	4	EFO_0009928

Protein segments in the cluster

Peptide	Gene	Start	Entry
PPPALPPPPRPVADK	CHRM4	276	P08173
LLWPQKPPPPPPQPL	FAM222A	286	Q5U5X8
PPHILPPEKRPPEPP	CDK12	1256	Q9NYV4
ETSNLQPPPPLPPPP	ALG13	951	Q9NP73
KEPEQEKPPSPPPPP	ANTXRL	391	A6NF34
KPLPPTPDLPQPHLP	ARHGEF5	811	Q12774
DKPRPPPLPSEPPPP	CCNT1	706	O60563
EPSPKALPEPLPAPP	ABHD8	421	Q96I13
PPDDPSPSEPLPKPP	ANKRD34A	221	Q69YU3
PQPEPQPLPDPAPLP	SLC16A2	51	P36021
PPPPAPEAQLPPFPR	RANBP3	76	Q9H6Z4
FLEQRSPPPPPPPPT	RBM33	476	Q96EV2
PPPIPAPLPPQAPPK	RAPH1	766	Q70E73
KALPPPPASIPPPPP	FMN1	866	Q68DA7
PPSPPSDPAQKPPPR	PTPN5	61	P54829
PTKPAPPAPPPPQNL	NCOR2	991	Q9Y618
SPKPPPPPTAPKPVK	CASKIN1	1271	Q8WXD9
GDKLQPSPPPLSPPP	KCNC2	51	Q96PR1
PPEIPPQGPPKISPQ	MAGEC3	391	Q8TD91
APPLQPPPPPPALSE	JSRP1	101	Q96MG2
PPEKEQPLLPPPPCP	KCNK4	296	Q9NYG8
PPPLPPQPPSRLPQK	ASAP2	876	O43150
TQLPPPPPGYPAPKP	ESPN	446	B1AK53
EEEKKPPPALPPPPP	KDM6B	766	O15054
PPPALPPPPPLAKFP	KDM6B	771	O15054
PPPPPLAKFPPPSQP	KDM6B	776	O15054
LAKFPPPSQPQPPPP	KDM6B	781	O15054
QPPPPPPPSPASLLK	KDM6B	791	O15054
DKPLPAPPPPLRDPP	CBLB	541	Q13191
PPPPPEALIPFCSPP	NHSL1	976	Q5SYE7
DKGPQQLLLPPPPPP	FOXG1	96	P55316
QLLLPPPPPPPPAAA	FOXG1	101	P55316
RLALPQPPPDPPAPP	IL11	146	P20809
PSKPPIQQPTPGKPP	PCLO	301	Q9Y6V0
PAKPPPQQPGPAKPP	PCLO	476	Q9Y6V0
KPQPPARPPPPVLPA	PDCD6IP	751	Q8WUM4
PGPPDPKKAPDPPTL	MYLK2	36	Q9H1R3
PQRPSLQKPPPPPPS	C19orf85	81	A0A1B0GUS0
KECPLAPLPPSPLPP	NPIPB8	301	E9PQR5
LLDPNASPPPPPPPR	MEX3D	126	Q86XN8
ALKQPPAPPPPPPPV	MAZ	126	P56270
EAPPLPLSPPAPPPA	MNT	61	Q99583
NSPQPLPPPPPLPAA	MNT	96	Q99583
LPPPPPLPAAAQPLP	MNT	101	Q99583
KTPLPAPPPPPAAPA	MNT	406	Q99583
QQASTPPPPPPPPLL	INF2	416	Q27J81
DQPLPDTKPLPPPQP	MED9	21	Q9NWA0
DTKPLPPPQPPPVPA	MED9	26	Q9NWA0
LPPPPPPPLPFQTSQ	FOSB	256	P53539
LLLEPPPPPSMAPPP	C6orf132	176	Q5T0Z8
VKATPPPPAPPPAPA	CHERP	351	Q8IWX8
LPPPPPPLPDKCPPA	FMNL3	526	Q8IVF7
PPLPDKCPPAPPLPG	FMNL3	531	Q8IVF7
PTPPIPAPAPKPAAP	BCL9	256	O00512
LPPPPDQLPPDPPSP	CC2D1A	311	Q6P1N0
PQKPPPGDLPPKPTE	ASAP1	931	Q9ULH1
PPPPPPPSCALQKKP	MBD5	336	Q9P267
PPPPPPPEESCPAKP	CCDC71L	151	Q8N9Z2
SLPSREPPPPQKPPP	MLLT1	451	Q03111
EPPPPQKPPPPNSKV	MLLT1	456	Q03111
TAGQPQPPPPKPPRP	FBN2	26	P35556
VELQPPPPAPLSPPP	PPP1R18	421	Q6NYC8
EVPPRPPSPPKKPSP	SLC15A2	21	Q16348
VPKPPPESPAPPSRP	INAVA	281	Q3KP66
KECPLAPLPPSPLPP	NPIPB6	301	E9PJ23
LNQPTEPPPKPVFPP	CAMSAP2	1101	Q08AD1
KQPPPGPLAPPKSPE	PTCHD3	41	Q3KNS1
PPPPPVLPLQPCSPA	RIN3	281	Q8TB24
PKLQPPLPPEPPEPN	MAP3K14	711	Q99558
PLPPEPPEPNKSPPL	MAP3K14	716	Q99558
ETPPPPPPPPAANLL	NYAP1	381	Q6ZVC0
PPPPALPPPASKEPP	RTL5	126	Q5HYW3
LPPPASKEPPPQPPL	RTL5	131	Q5HYW3
LPTPPPAPPPEPEKE	SPEF2	911	Q9C093
PELPPSPASPPEQPP	PWWP2A	111	Q96N64
PPQAPLPLPTQPPSP	TFEB	376	P19484
PPPPLQKNTPLPQSP	THAP8	106	Q8NA92
DPPAIPPRQPPPPKV	SOS2	1171	Q07890
QQPPTKVPPERPPPP	SH3D19	336	Q5HYK7
PPPPPPPSRCLPQDE	TGFBR3L	191	H3BV60
PKPRNRPSVPPPPQP	ARHGAP17	801	Q68EM7
LAAAPAPLPQPPPPP	MEX3C	11	Q5U5Q3
PPPPEVTDLPKKPPP	PRAM1	71	Q96QH2
PPPEVTDLPKKPPPP	PRAM1	96	Q96QH2
PKPPPPIIVVPDPPS	RHOBTB2	236	Q9BYZ6
PETPPKPPDAPPLGP	RETREG2	511	Q8NC44
PPAVPKELPAPPAPP	PRRC2A	521	P48634
PAPQAPPPPPKALYP	PRRC2A	691	P48634
APAPPPLPPAEPLAK	SETD1B	431	Q9UPS6
PPPPPSPPLEPVPKT	POLD3	351	Q15054
LPPRPPPPAPVNDEP	MTA1	696	Q13330
PLLEEKPPPTPPPAP	PRR12	1451	Q9ULL5
KPPPTPPPAPTPQPQ	PRR12	1456	Q9ULL5
PPPQPALPSPPPLVA	PRR12	1476	Q9ULL5
APPPKAPAPPPKPET	PRR12	1691	Q9ULL5
KPVEPPQPTAPPAPP	SETDB1	446	Q15047
PSQDKPLPPPPPGSL	SOAT2	76	O75908
PSPPPCPPEIPPKPV	ARAP1	206	Q96P48
LEEGPAPLPPPPPKE	PRR22	176	Q8IZ63
PEPPKAELQLPPPPP	SF3B2	6	Q13435
TKPLLQTPPPPPPPP	ZFHX4	3106	Q86UP3
PLPPPPPLPKIQPLE	ZBTB21	986	Q9ULJ3
KPDPPLPPAFGAPPP	ZNF865	121	P0CJ78
AATPPPPPQPPKAEL	ZFHX2	1391	Q9C0A1
LPSPTKEKPPPPPPG	SYNGAP1	786	Q96PV0
KSAEPPPEQPPPPPP	SOBP	736	A7XYQ1
TPPPKAAPPPPALTP	SCAF1	976	Q9H7N4
ENSPGDLPPPPLPPP	ROBO3	1261	Q96MS0
PPPPPPPAPEVLASA	WASH2P	306	Q6VEQ5
PPPPPAPEVLASAPP	WASH4P	321	A8MWX3
PQQKAPLVPPPPPPP	SRPK2	16	P78362
PPPPPPPAPEVLASA	WASHC1	306	A8K0Z3
PKPPLPEGEVPPPRP	VCL	861	P18206
PPPPPAPEVLASAPP	WASH3P	306	C4AMC7
PSRALDDKPPPPPPP	WIPF1	256	O43516
PLSLPPDAAPKPPIP	PHC1	481	P78364
VQPGAPPPPLPKAPS	TACC2	526	O95359
PVKAPPAPPPPPPEV	TACC2	1961	O95359
PPPPVPPPAIKSPTA	ROBO1	1481	Q9Y6N7
EKPSPPQPPPPPSVP	NSD3	126	Q9BZ95
SDLPPPPPPPLAPQK	SKOR2	831	Q2VWA4
KEGRPLPPPPPPSLN	ZC2HC1B	101	Q5TFG8
EPPPPPPPESAPSKP	SMARCA5	6	O60264
KLLPPPATPPPPPQS	SMAD5-AS1	6	Q9Y6J3
PSKEKAAPPPPPPPP	UBR4	601	Q5T4S7
PPPPKAPPFPKAEGP	ZNF580	21	Q9UK33
PTSPPPPPPPLKAEQ	ZNF579	481	Q8NAF0
LPPLPPEDPEQPPKP	ZFC3H1	601	O60293
PLPPNLKPAPPPTIE	SON	2076	P18583
PTPPPPPPPATPRKN	ZMYM3	816	Q14202
PKDAPPAPAVPPAPP	UNCX	406	A6NJT0
SLPSLPQPPPQAPPP	ZFHX3	2476	Q15911
EPLAPAAPVPPPPPS	ZNF628	431	Q5EBL2
PTPPPPPAPPKLILL	ZNF628	731	Q5EBL2
PLPPPPPLAQVAPSP	MYPOP	226	Q86VE0
AAPPPAKPPPPPQPL	GRIN2D	901	O15399
AKPPPPPQPLPSPAY	GRIN2D	906	O15399
PLSPPAAQPPQKPPP	GRIN2D	991	O15399