Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1

1.53e-0781997GO:0015370
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

NPC1 PLXNA3 LPAR3 GPR17 RAMP3 HTR5A GPR182 ACVR2A SSTR1 PTCH1 GRM3 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 HMCN2 NPY4R OR1E1 LPAR2 TNFRSF1B CHRNA10

5.92e-0713539922GO:0004888
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-7 ERVK-8 ERVK-19 ERVK-25

1.04e-0637995GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-7 ERVK-8 ERVK-19 ERVK-25

1.19e-0638995GO:0070001
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC5A5 SLC6A12 SLC18A1 SLC18A2

2.08e-0619994GO:0015373
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1

2.12e-06119997GO:0015294
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

RAMP3 GPR182 SSTR1 F2RL2 QRFPR NPY4R2 NPY4R

4.44e-06133997GO:0008528
GeneOntologyMolecularFunctionpeptide receptor activity

RAMP3 GPR182 SSTR1 F2RL2 QRFPR NPY4R2 NPY4R

6.23e-06140997GO:0001653
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC5A5 SLC6A12 SLC18A1 SLC18A2

7.82e-0626994GO:0015296
GeneOntologyMolecularFunctionsymporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1

9.80e-06150997GO:0015293
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.06e-0528994GO:0001972
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7 ERVK-8

1.90e-0511993GO:0004523
GeneOntologyMolecularFunctionneuropeptide Y receptor activity

QRFPR NPY4R2 NPY4R

1.90e-0511993GO:0004983
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1

2.29e-05171997GO:0015081
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

SLC17A3 SLC18A1 SLC18A2 SLC29A4

2.35e-0534994GO:0042910
GeneOntologyMolecularFunctionfatty acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

2.37e-0569995GO:0005504
GeneOntologyMolecularFunctionmonoamine transmembrane transporter activity

SLC18A1 SLC18A2 SLC29A4

2.52e-0512993GO:0008504
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.65e-0535994GO:0015020
GeneOntologyMolecularFunctionG protein-coupled receptor activity

LPAR3 GPR17 RAMP3 HTR5A GPR182 SSTR1 GRM3 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 NPY4R OR1E1 LPAR2

2.91e-058849915GO:0004930
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-8

4.14e-0514993GO:0003964
GeneOntologyMolecularFunctionsteroid binding

NPC1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 PTCH1

5.26e-05133996GO:0005496
GeneOntologyMolecularFunctionserotonin:sodium:chloride symporter activity

SLC18A1 SLC18A2

7.28e-053992GO:0005335
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A12 SLC18A1 SLC18A2

7.64e-0517993GO:0015378
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 ERVK-7 FAN1 ERVK-8

7.91e-0546994GO:0016893
GeneOntologyMolecularFunctionretinoid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.36e-0548994GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.01e-0449994GO:0019840
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2

1.06e-04151996GO:0008509
GeneOntologyMolecularFunctionneuropeptide receptor activity

SSTR1 QRFPR NPY4R2 NPY4R

1.38e-0453994GO:0008188
GeneOntologyMolecularFunctionmonoamine:proton antiporter activity

SLC18A1 SLC18A2

1.45e-044992GO:0015311
GeneOntologyMolecularFunctionpancreatic polypeptide receptor activity

NPY4R2 NPY4R

1.45e-044992GO:0001602
GeneOntologyMolecularFunctionadrenomedullin receptor activity

RAMP3 GPR182

1.45e-044992GO:0001605
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-8

1.47e-0421993GO:0035613
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

1.93e-04107995GO:0033293
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A12 SLC18A1 SLC18A2

1.95e-0423993GO:0015377
GeneOntologyMolecularFunctionbeta-galactosidase activity

GLB1L3 GLB1L2

2.41e-045992GO:0004565
GeneOntologyMolecularFunctionlysophosphatidic acid receptor activity

LPAR3 LPAR2

2.41e-045992GO:0070915
GeneOntologyMolecularFunctiongap junction channel activity

GJB6 GJA9 GJB1

2.51e-0425993GO:0005243
GeneOntologyMolecularFunctionprotein kinase C binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.24e-0466994GO:0005080
GeneOntologyMolecularFunctioneukaryotic translation initiation factor 2alpha kinase activity

STK35 PDIK1L

3.60e-046992GO:0004694
GeneOntologyMolecularFunctioncalcitonin family receptor activity

RAMP3 GPR182

5.03e-047992GO:0097642
GeneOntologyMolecularFunctiongalactosidase activity

GLB1L3 GLB1L2

5.03e-047992GO:0015925
GeneOntologyMolecularFunctiontransporter activity

NPC1 SLC17A3 GJB6 PIEZO1 SLC1A6 SLC5A5 GJA9 SLC6A12 GJB1 SLC18A1 SLC18A2 CHRNA10 SLC23A1 SLC29A4 SLC38A8 SLC23A3

5.79e-0412899916GO:0005215
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1

6.82e-04296997GO:0015291
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC17A3 GJB6 PIEZO1 SLC1A6 SLC5A5 GJA9 SLC6A12 GJB1 SLC18A1 SLC18A2 CHRNA10 SLC23A1 SLC29A4 SLC38A8 SLC23A3

6.85e-0411809915GO:0022857
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC1A6 SLC6A12 SLC23A1

6.90e-0435993GO:0005343
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1

7.52e-04301997GO:0022853
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 ERVK-7 ERVK-8

8.13e-0437993GO:0016891
GeneOntologyMolecularFunctionneuropeptide binding

SSTR1 NPY4R2 NPY4R

8.13e-0437993GO:0042923
GeneOntologyMolecularFunctionwide pore channel activity

GJB6 GJA9 GJB1

8.13e-0437993GO:0022829
GeneOntologyMolecularFunctionurate transmembrane transporter activity

SLC17A3 SLC23A1

8.56e-049992GO:0015143
GeneOntologyMolecularFunctionsalt transmembrane transporter activity

SLC17A3 SLC23A1

8.56e-049992GO:1901702
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-8

8.79e-0438993GO:0034061
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO7B MYO9A MYO9B

8.79e-0438993GO:0000146
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 CDS1 GALT ERVK-7 ERVK-8

9.63e-04152995GO:0016779
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3 SIGLEC10

1.22e-03239996GO:0031406
GeneOntologyMolecularFunctiontoxin transmembrane transporter activity

SLC17A3 SLC29A4

1.55e-0312992GO:0019534
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC17A3 SLC5A5 SLC6A12 SLC18A1 SLC18A2

1.62e-03171995GO:0015103
GeneOntologyMolecularFunctionorganic acid binding

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3 SIGLEC10

1.67e-03254996GO:0043177
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC17A3 PIEZO1 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 CHRNA10 SLC23A1 SLC29A4

1.68e-036649910GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 CHRNA10 SLC23A1

2.19e-03465998GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC17A3 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1 SLC29A4

2.57e-03477998GO:0022804
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

SLC17A3 SLC29A4

2.79e-0316992GO:0015562
GeneOntologyMolecularFunctionbioactive lipid receptor activity

LPAR3 LPAR2

2.79e-0316992GO:0045125
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO7B MYO9A MYO9B DYNC1H1

2.83e-03118994GO:0003774
GeneOntologyMolecularFunctionlipid binding

NPC1 LPAR3 UGT1A10 UGT1A8 UGT1A7 UGT1A9 PTCH1 DYSF MAP3K1 GSTA3 CLN6 LPAR2

3.53e-039889912GO:0008289
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC1A6 SLC6A12 SLC23A1 SLC29A4 SLC38A8

3.79e-03208995GO:0005342
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9 POMT1

4.02e-03211995GO:0016758
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 EXOSC3 ERVK-7 ERVK-8

4.70e-03136994GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 ERVK-7 FAN1 ERVK-8

4.70e-03136994GO:0004519
GeneOntologyMolecularFunctionendopeptidase activity

CAPN12 ERVK-6 ERVK-7 TLL1 ERVK-8 ERVK-19 ERVK-25

5.57e-03430997GO:0004175
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC1A6 SLC6A12

5.75e-0323992GO:0005283
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 EXOSC3 ERVK-7 FAN1 ERVK-8

5.88e-03231995GO:0004518
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC17A3 PIEZO1 SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 CHRNA10 SLC23A1 SLC29A4

5.95e-037939910GO:0015075
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.11e-03153994GO:0008194
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 ERVK-7 ERVK-8

7.12e-0379993GO:0004521
GeneOntologyMolecularFunctionprotein homodimerization activity

ERVK-6 MYO9B UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3 SLC5A5 CLN6 G6PD

7.16e-038159910GO:0042803
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC1A6 SLC6A12

9.05e-0329992GO:0005416
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.39e-095984GO:0006711
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.13e-096984GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.13e-096984GO:0046226
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.13e-096984GO:0051552
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.84e-0810984GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.84e-0810984GO:0009804
GeneOntologyBiologicalProcessflavonoid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.32e-0713984GO:0009812
GeneOntologyBiologicalProcessflavonoid glucuronidation

UGT1A8 UGT1A7 UGT1A9

1.03e-065983GO:0052696
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.70e-0621984GO:0052695
GeneOntologyBiologicalProcesshormone catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.70e-0621984GO:0042447
GeneOntologyBiologicalProcessneurotransmitter uptake

SLC1A6 SLC6A12 SLC18A1 SLC18A2 SLC29A4

4.76e-0652985GO:0001504
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.61e-0626984GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.61e-0626984GO:0006063
GeneOntologyBiologicalProcesssecondary metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

1.67e-0567985GO:0019748
GeneOntologyBiologicalProcesssteroid catabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.99e-0534984GO:0006706
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT1A8 UGT1A7 UGT1A9

2.22e-0512983GO:0052697
GeneOntologyBiologicalProcessDNA integration

ERVK-6 ERVK-7 ERVK-8

2.87e-0513983GO:0015074
GeneOntologyBiologicalProcessneurotransmitter reuptake

SLC6A12 SLC18A1 SLC18A2 SLC29A4

3.12e-0538984GO:0098810
GeneOntologyBiologicalProcessserotonin uptake

SLC18A1 SLC18A2 SLC29A4

3.64e-0514983GO:0051610
GeneOntologyBiologicalProcessestrogen metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.09e-0452984GO:0008210
GeneOntologyBiologicalProcesshistamine uptake

SLC18A2 SLC29A4

1.33e-044982GO:0051615
GeneOntologyBiologicalProcessaminergic neurotransmitter loading into synaptic vesicle

SLC18A1 SLC18A2

1.33e-044982GO:0015842
GeneOntologyBiologicalProcessxenobiotic transport

SLC17A3 SLC18A1 SLC18A2 SLC29A4

2.45e-0464984GO:0042908
GeneOntologyBiologicalProcessadenylate cyclase-activating G protein-coupled receptor signaling pathway

LPAR3 RAMP3 HTR5A ADORA2B GPR161 LPAR2

3.03e-04191986GO:0007189
GeneOntologyBiologicalProcessliver development

NPC1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 PTCH1

4.08e-04202986GO:0001889
GeneOntologyBiologicalProcesssteroid metabolic process

NPC1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 ADORA2B CLN6 G6PD

4.28e-04376988GO:0008202
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

LPAR3 RAMP3 HTR5A GRM3 ADORA2B GPR161 LPAR2

4.32e-04286987GO:0007188
GeneOntologyBiologicalProcesshepaticobiliary system development

NPC1 UGT1A10 UGT1A8 UGT1A7 UGT1A9 PTCH1

4.41e-04205986GO:0061008
GeneOntologyBiologicalProcessserotonin transport

SLC18A1 SLC18A2 SLC29A4

4.67e-0432983GO:0006837
GeneOntologyBiologicalProcessxenobiotic metabolic process

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

5.67e-04141985GO:0006805
GeneOntologyBiologicalProcesscellular response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3 SLC18A2

6.71e-04222986GO:0071466
GeneOntologyBiologicalProcessnucleobase-containing small molecule catabolic process

GALT DERA APOBEC2

7.19e-0437983GO:0034656
GeneOntologyBiologicalProcesscell-cell fusion

DOCK1 ERVK-6 ERVK-8 ERVK-19

7.23e-0485984GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

DOCK1 ERVK-6 ERVK-8 ERVK-19

7.23e-0485984GO:0000768
GeneOntologyBiologicalProcessnorepinephrine transport

ADORA2B SLC18A1 SLC29A4

7.78e-0438983GO:0015874
GeneOntologyBiologicalProcessnorepinephrine uptake

SLC18A1 SLC29A4

7.87e-049982GO:0051620
GeneOntologyBiologicalProcesssyncytium formation

DOCK1 ERVK-6 ERVK-8 ERVK-19

8.59e-0489984GO:0006949
GeneOntologyCellularComponentconnexin complex

GJB6 GJA9 GJB1

1.53e-04221003GO:0005922
GeneOntologyCellularComponentclathrin-sculpted monoamine transport vesicle

SLC18A1 SLC18A2

2.24e-0451002GO:0070081
GeneOntologyCellularComponentclathrin-sculpted monoamine transport vesicle membrane

SLC18A1 SLC18A2

2.24e-0451002GO:0070083
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

ILDR2 UBE2J1 CDS1 SLC17A3 UGT1A10 UGT1A8 UGT1A7 PIEZO1 UGT1A9 POMT1 PAPPA-AS1 GJB1 SLC18A1 CNEP1R1 CLN6 TRAF3IP3

5.42e-04132710016GO:0042175
GeneOntologyCellularComponentgap junction

GJB6 GJA9 GJB1

7.33e-04371003GO:0005921
GeneOntologyCellularComponentaxon

LPAR3 MYO9A PTCH1 GRM3 HMCN2 SLC18A1 SLC18A2 AP3B2 TNFRSF1B CHRNA10 DYNC1H1 SLC38A8

1.12e-0389110012GO:0030424
GeneOntologyCellularComponentendoplasmic reticulum membrane

ILDR2 UBE2J1 CDS1 SLC17A3 UGT1A10 UGT1A8 UGT1A7 PIEZO1 UGT1A9 POMT1 PAPPA-AS1 GJB1 SLC18A1 CLN6 TRAF3IP3

1.21e-03129310015GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

ILDR2 UBE2J1 CDS1 SLC17A3 UGT1A10 UGT1A8 UGT1A7 PIEZO1 UGT1A9 POMT1 PAPPA-AS1 GJB1 SLC18A1 CLN6 TRAF3IP3

1.27e-03129910015GO:0098827
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.96e-0621914PF00201
DomainUDPGT

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.96e-0621914PS00375
DomainUDP_glucos_trans

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.96e-0621914IPR002213
DomainNPY_rcpt

QRFPR NPY4R2 NPY4R

9.20e-069913IPR000611
DomainGPCR_Rhodpsn_7TM

LPAR3 GPR17 HTR5A GPR182 SSTR1 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 NPY4R OR1E1 LPAR2

2.12e-056709113IPR017452
DomainNPY4_rcpt

NPY4R2 NPY4R

2.35e-052912IPR001933
Domain7tm_1

LPAR3 GPR17 HTR5A GPR182 SSTR1 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 NPY4R OR1E1 LPAR2

2.36e-056779113PF00001
DomainG_PROTEIN_RECEP_F1_1

LPAR3 GPR17 HTR5A GPR182 SSTR1 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 NPY4R OR1E1 LPAR2

2.67e-056859113PS00237
DomainG_PROTEIN_RECEP_F1_2

LPAR3 GPR17 HTR5A GPR182 SSTR1 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 NPY4R OR1E1 LPAR2

2.92e-056919113PS50262
DomainGPCR_Rhodpsn

LPAR3 GPR17 HTR5A GPR182 SSTR1 F2RL2 ADORA2B GPR161 QRFPR NPY4R2 NPY4R OR1E1 LPAR2

2.97e-056929113IPR000276
DomainXan_ur_permease

SLC23A1 SLC23A3

7.02e-053912PF00860
DomainXant/urac/vitC

SLC23A1 SLC23A3

7.02e-053912IPR006043
DomainLPA_rcpt

LPAR3 LPAR2

7.02e-053912IPR004065
DomainCONNEXINS_1

GJB6 GJA9 GJB1

1.02e-0419913PS00407
DomainCONNEXINS_2

GJB6 GJA9 GJB1

1.20e-0420913PS00408
DomainConnexin

GJB6 GJA9 GJB1

1.20e-0420913IPR000500
DomainConnexin_CCC

GJB6 GJA9 GJB1

1.20e-0420913IPR019570
DomainConnexin_N

GJB6 GJA9 GJB1

1.20e-0420913IPR013092
DomainConnexin

GJB6 GJA9 GJB1

1.20e-0420913PF00029
DomainConnexin_CCC

GJB6 GJA9 GJB1

1.20e-0420913SM01089
DomainConnexin_CS

GJB6 GJA9 GJB1

1.20e-0420913IPR017990
DomainCNX

GJB6 GJA9 GJB1

1.20e-0420913SM00037
DomainGlyco_hydro_35

GLB1L3 GLB1L2

1.40e-044912PF01301
DomainGly_Hdrlase_35_cat

GLB1L3 GLB1L2

1.40e-044912IPR031330
DomainGlycoside_Hdrlase_35

GLB1L3 GLB1L2

1.40e-044912IPR001944
DomainB-gal_1-like

GLB1L3 GLB1L2

1.40e-044912IPR026283
DomainGLYCOSYL_HYDROL_F35

GLB1L3 GLB1L2

1.40e-044912PS01182
DomainPtc/Disp

NPC1 PTCH1

8.27e-049912IPR003392
DomainPatched

NPC1 PTCH1

8.27e-049912PF02460
DomainMyosin_head_motor_dom

MYO7B MYO9A MYO9B

8.34e-0438913IPR001609
DomainMYOSIN_MOTOR

MYO7B MYO9A MYO9B

8.34e-0438913PS51456
DomainMyosin_head

MYO7B MYO9A MYO9B

8.34e-0438913PF00063
DomainMYSc

MYO7B MYO9A MYO9B

8.34e-0438913SM00242
DomainSSD

NPC1 PTCH1

1.77e-0313912IPR000731
DomainSSD

NPC1 PTCH1

1.77e-0313912PS50156
Domain7TM_GPCR_Srsx

LPAR3 SSTR1 ADORA2B LPAR2

2.19e-03112914SM01381
DomainMFS_dom

SLC17A3 SLC18A1 SLC18A2 SLC29A4

4.18e-03134914IPR020846
DomainIQ

MYO7B MYO9A MYO9B

5.04e-0371913PF00612
DomainMFS_1

SLC17A3 SLC18A1 SLC18A2

6.31e-0377913PF07690
DomainMFS

SLC17A3 SLC18A1 SLC18A2

6.31e-0377913IPR011701
DomainIQ

MYO7B MYO9A MYO9B

7.26e-0381913SM00015
PathwayWP_ESTROGEN_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

7.97e-0822735MM15888
PathwayWP_GPCRS_NONODORANT

LPAR3 GPR17 HTR5A SSTR1 GRM3 F2RL2 ADORA2B QRFPR NPY4R LPAR2

1.06e-062667310MM15843
PathwayREACTOME_GPCR_LIGAND_BINDING

LPAR3 GPR17 RAMP3 HTR5A SSTR1 PTCH1 GRM3 F2RL2 ADORA2B QRFPR NPY4R LPAR2

4.07e-064637312M507
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.50e-0624734MM14599
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.71e-0625734M17787
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.71e-0625734MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.71e-0625734M605
PathwayWP_GLUCURONIDATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.08e-0626734M39404
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

LPAR3 HTR5A SSTR1 GRM3 F2RL2 ADORA2B NPY4R LPAR2 CHRNA10

1.07e-05272739M13380
PathwayREACTOME_GPCR_LIGAND_BINDING

LPAR3 GPR17 RAMP3 HTR5A SSTR1 GRM3 F2RL2 ADORA2B QRFPR NPY4R LPAR2

1.21e-054307311MM15160
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.23e-0528734M19580
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

3.02e-0570735M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

3.46e-0572735M9257
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT1A10 UGT1A8 UGT1A9

4.65e-0514733M39328
PathwayREACTOME_PARACETAMOL_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.75e-0539734MM15695
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

LPAR3 GPR17 HTR5A SSTR1 F2RL2 ADORA2B QRFPR NPY4R LPAR2

4.92e-05330739M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

LPAR3 GPR17 HTR5A SSTR1 F2RL2 ADORA2B QRFPR NPY4R LPAR2

5.28e-05333739MM14963
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

GPR17 HTR5A SSTR1 F2RL2 ADORA2B GPR161 NPY4R OR1E1

5.74e-05260738M39397
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.80e-0541734M7399
PathwayREACTOME_ASPIRIN_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.40e-0545734MM15694
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A12 SLC18A1 SLC18A2

1.22e-0419733M27362
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A12 SLC18A1 SLC18A2

1.22e-0419733MM15107
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.38e-0451734M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.48e-0452734M14171
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.85e-0455734M14933
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

2.29e-04107735MM14595
PathwayREACTOME_SIGNALING_BY_GPCR

LPAR3 GPR17 RAMP3 HTR5A SSTR1 PTCH1 GRM3 F2RL2 ADORA2B QRFPR NPY4R LPAR2

2.37e-047027312M746
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

2.49e-04109735M18788
PathwayKEGG_RETINOL_METABOLISM

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.32e-0464734M9488
PathwayREACTOME_DRUG_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

3.74e-04119735MM15692
PathwayREACTOME_SIGNALING_BY_GPCR

LPAR3 GPR17 RAMP3 HTR5A SSTR1 GRM3 F2RL2 ADORA2B QRFPR NPY4R LPAR2

4.59e-046467311MM14962
PathwayWP_PENTOSE_PHOSPHATE_PATHWAY_IN_SENESCENT_CELLS

DERA G6PD

7.26e-048732M42529
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

LPAR3 GPR17 HTR5A SSTR1 GRM3 NPY4R LPAR2

7.26e-04289737MM15057
PathwayWP_NRF2_PATHWAY

UGT1A7 UGT1A9 GSTA3 SLC5A5 G6PD

8.12e-04141735M39454
PathwayBIOCARTA_AKAP13_PATHWAY

LPAR3 LPAR2

9.30e-049732MM1477
PathwayKEGG_MEDICUS_REFERENCE_LPA_GNAQ_11_RHOA_SIGNALING_PATHWAY

LPAR3 LPAR2

9.30e-049732M47732
PathwayREACTOME_GAP_JUNCTION_ASSEMBLY

GJB6 GJA9 GJB1

9.87e-0438733M14981
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

1.17e-03153735MM15844
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

LPAR3 GPR17 HTR5A SSTR1 GRM3 NPY4R LPAR2

1.18e-03314737M600
PathwayBIOCARTA_AKAP13_PATHWAY

LPAR3 LPAR2

1.41e-0311732M17668
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC29A4

1.44e-03238736MM15076
PathwayREACTOME_ASPIRIN_ADME

UGT1A8 UGT1A7 UGT1A9

1.52e-0344733M45014
PathwayWP_IRINOTECAN_PATHWAY

UGT1A10 UGT1A9

1.69e-0312732M39611
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC1A6 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC29A4

1.81e-03249736M5988
PathwayKEGG_MEDICUS_REFERENCE_LPA_GNA12_13_RHOA_SIGNALING_PATHWAY

LPAR3 LPAR2

1.99e-0313732M47731
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

LPAR3 LPAR2

2.31e-0314732M27331
PathwayREACTOME_LYSOSPHINGOLIPID_AND_LPA_RECEPTORS

LPAR3 LPAR2

2.31e-0314732MM15062
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A6 SLC6A12 SLC18A2

2.32e-0351733M4281
PathwayREACTOME_NEUROTRANSMITTER_RELEASE_CYCLE

SLC1A6 SLC6A12 SLC18A2

2.32e-0351733MM14499
PathwayREACTOME_GAP_JUNCTION_TRAFFICKING_AND_REGULATION

GJB6 GJA9 GJB1

2.32e-0351733M26972
PathwayREACTOME_DRUG_ADME

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.44e-03109734M45012
PathwayREACTOME_KERATAN_SULFATE_DEGRADATION

GLB1L3 GLB1L2

2.66e-0315732M691
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

DERA G6PD

2.66e-0315732M27682
PathwayREACTOME_PENTOSE_PHOSPHATE_PATHWAY

DERA G6PD

2.66e-0315732MM15404
PathwayREACTOME_KERATAN_SULFATE_DEGRADATION

GLB1L3 GLB1L2

2.66e-0315732MM14799
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

HTR5A SSTR1 F2RL2 ADORA2B NPY4R

2.76e-03186735MM15994
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

GPR17 ADORA2B

3.03e-0316732MM15050
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

GPR17 ADORA2B

3.03e-0316732M6786
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A10 UGT1A8 UGT1A7 UGT1A9 G6PD

1.38e-1012100519419973
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

RAMP3 UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.24e-1013100525246029
Pubmed

Circadian Clock Component Rev-erbα Regulates Diurnal Rhythm of UDP-Glucuronosyltransferase 1a9 and Drug Glucuronidation in Mice.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.61e-106100432527940
Pubmed

Use of glucuronidation fingerprinting to describe and predict mono- and dihydroxyflavone metabolism by recombinant UGT isoforms and human intestinal and liver microsomes.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.61e-106100420297805
Pubmed

Assignment of the human UDP glucuronosyltransferase gene (UGT1A1) to chromosome region 2q37.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.24e-09710048467709
Pubmed

Molecular cloning of two cDNAs encoding the mouse bilirubin/phenol family of UDP-glucuronosyltransferases (mUGTBr/p).

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.24e-09710048464825
Pubmed

Cyp3a11-mediated testosterone-6β-hydroxylation decreased, while UGT1a9-mediated propofol O-glucuronidation increased, in mice with diabetes mellitus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.24e-097100427514509
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.46e-098100417179145
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.46e-098100420610558
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.46e-098100418052087
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.02e-099100422511988
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.33e-0810100423642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.33e-0810100411465080
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.33e-0810100423371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.33e-0810100422558097
Pubmed

Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element.

UGT1A10 UGT1A8 UGT1A9

2.31e-083100329519853
Pubmed

Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region.

UGT1A10 UGT1A8 UGT1A9

2.31e-083100312847094
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.13e-0812100420308471
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.13e-0812100411434514
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.51e-0813100422085899
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.30e-0814100421646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.30e-0814100410836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.30e-0814100414672974
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.30e-081410049295054
Pubmed

Irinotecan pharmacokinetics/pharmacodynamics and UGT1A genetic polymorphisms in Japanese: roles of UGT1A1*6 and *28.

UGT1A10 UGT1A7 UGT1A9

9.21e-084100317558305
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.14e-0716100419414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.49e-0717100420639394
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.91e-0718100420056724
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-7 ERVK-19

2.30e-075100312629516
Pubmed

Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele.

UGT1A8 UGT1A7 UGT1A9

2.30e-075100320565459
Pubmed

Variation of hepatic glucuronidation: Novel functional polymorphisms of the UDP-glucuronosyltransferase UGT1A4.

UGT1A10 UGT1A8 UGT1A9

2.30e-075100315057901
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.41e-0719100423281178
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.54e-0724100424625756
Pubmed

Tails of unconventional myosins.

MYO7B MYO9A MYO9B

8.01e-077100311212352
Pubmed

Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis.

HTR5A GRM3 SLC1A6 SLC18A1 SLC18A2 CHRNA10

1.23e-06118100619156168
Pubmed

Family-based genome-wide association scan of attention-deficit/hyperactivity disorder.

UGT1A10 UGT1A8 UGT1A9

1.91e-069100320732626
Pubmed

Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.

LPAR3 GPR17 HTR5A NPY4R LPAR2

2.61e-067510052834384
Pubmed

Influence of drug transporters and UGT polymorphisms on pharmacokinetics of phenolic glucuronide metabolite of mycophenolic acid in Japanese renal transplant recipients.

UGT1A8 UGT1A7 UGT1A9

3.74e-0611100318695635
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-8 ERVK-19

4.98e-0612100314557543
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-7 ERVK-8 ERVK-19 ERVK-25

7.96e-0694100521542922
Pubmed

Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells.

LPAR3 LPAR2

8.18e-062100225463482
Pubmed

Lysophosphatidic acid receptors 2 and 3 regulate erythropoiesis at different hematopoietic stages.

LPAR3 LPAR2

8.18e-062100233035680
Pubmed

Expression of the two isoforms of the vesicular monoamine transporter (VMAT1 and VMAT2) in the endocrine pancreas and pancreatic endocrine tumors.

SLC18A1 SLC18A2

8.18e-062100212871984
Pubmed

Lysosome lipid storage disorder in NCTR-BALB/c mice. I. Description of the disease and genetics.

NPC1 LPAR2

8.18e-06210026765731
Pubmed

Class IX Myosins: Motorized RhoGAP Signaling Molecules.

MYO9A MYO9B

8.18e-062100232451867
Pubmed

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

UGT1A10 UGT1A9

8.18e-062100225547628
Pubmed

Effects of lysophosphatidic acid (LPA) receptor-2 (LPA2) and LPA3 on the regulation of chemoresistance to anticancer drug in lung cancer cells.

LPAR3 LPAR2

8.18e-062100232006610
Pubmed

Transcriptional regulation of lysophosphatidic acid receptors 2 and 3 regulates myeloid commitment of hematopoietic stem cells.

LPAR3 LPAR2

8.18e-062100233406026
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

8.18e-06210029060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

8.18e-06210029460924
Pubmed

Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis.

LPAR3 LPAR2

8.18e-062100227244685
Pubmed

Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues.

UGT1A10 UGT1A8

8.18e-062100211901093
Pubmed

Identifying and characterizing a novel protein kinase STK35L1 and deciphering its orthologs and close-homologs in vertebrates.

STK35 PDIK1L

8.18e-062100219756140
Pubmed

Chromosomal localization of the human vesicular amine transporter genes.

SLC18A1 SLC18A2

8.18e-06210027905859
Pubmed

Genetic link of hepatocellular carcinoma with polymorphisms of the UDP-glucuronosyltransferase UGT1A7 gene.

UGT1A7 UGT1A9

8.18e-062100211677206
Pubmed

Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.

UGT1A10 UGT1A9

8.18e-062100222031623
Pubmed

Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10.

UGT1A10 UGT1A8

8.18e-062100210497143
Pubmed

Pharmacogenetic effect of the UGT polymorphisms on mycophenolate is modified by calcineurin inhibitors.

UGT1A8 UGT1A9

8.18e-062100218568343
Pubmed

Human UGT1A8 and UGT1A10 mRNA are expressed in primary human hepatocytes.

UGT1A10 UGT1A8

8.18e-062100217603215
Pubmed

UGT1A7 and UGT1A9 polymorphisms predict response and toxicity in colorectal cancer patients treated with capecitabine/irinotecan.

UGT1A7 UGT1A9

8.18e-062100215709193
Pubmed

Novel functional polymorphisms in the UGT1A7 and UGT1A9 glucuronidating enzymes in Caucasian and African-American subjects and their impact on the metabolism of 7-ethyl-10-hydroxycamptothecin and flavopiridol anticancer drugs.

UGT1A7 UGT1A9

8.18e-062100212944498
Pubmed

Identification of dopamine plasma membrane and vesicular transporters in human peripheral blood lymphocytes.

SLC18A1 SLC18A2

8.18e-062100211431013
Pubmed

Vesicular monoamine transporter protein expression correlates with clinical features, tumor biology, and MIBG avidity in neuroblastoma: a report from the Children's Oncology Group.

SLC18A1 SLC18A2

8.18e-062100226338179
Pubmed

Sclerosing Paragangliomas: Correlations of Histological Features with Patients' Genotype and Vesicular Monoamine Transporter Expression.

SLC18A1 SLC18A2

8.18e-062100235524772
Pubmed

Distinct pharmacological properties and distribution in neurons and endocrine cells of two isoforms of the human vesicular monoamine transporter.

SLC18A1 SLC18A2

8.18e-06210028643547
Pubmed

Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells.

LPAR3 LPAR2

8.18e-062100219001604
Pubmed

Characterization of two UDP glucuronosyltransferases that are predominantly expressed in human colon.

UGT1A10 UGT1A8

8.18e-06210029647757
Pubmed

Influence of UGT1A7 and UGT1A9 intronic I399 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients.

UGT1A7 UGT1A9

8.18e-062100217529886
Pubmed

How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?

UGT1A10 UGT1A9

8.18e-062100220089735
Pubmed

Roles of endothelial cells in the regulation of cell motility via lysophosphatidic acid receptor-2 (LPA2) and LPA3 in osteosarcoma cells.

LPAR3 LPAR2

8.18e-062100233347862
Pubmed

Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.

MYO7B MYO9A MYO9B

8.20e-061410038022818
Pubmed

Mapping of unconventional myosins in mouse and human.

MYO7B MYO9A MYO9B GSTA3

1.14e-054810048884266
Pubmed

An atlas of genetic influences on human blood metabolites.

SLC17A3 UGT1A10 UGT1A8 UGT1A7 UGT1A9 SLC6A12

1.91e-05190100624816252
Pubmed

Human metabolic individuality in biomedical and pharmaceutical research.

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.26e-0557100421886157
Pubmed

Predictive role of the UGT1A1, UGT1A7, and UGT1A9 genetic variants and their haplotypes on the outcome of metastatic colorectal cancer patients treated with fluorouracil, leucovorin, and irinotecan.

UGT1A7 UGT1A9

2.45e-053100219364970
Pubmed

Comprehensive analysis of UGT1A polymorphisms predictive for pharmacokinetics and treatment outcome in patients with non-small-cell lung cancer treated with irinotecan and cisplatin.

UGT1A7 UGT1A9

2.45e-053100216636344
Pubmed

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

UGT1A10 UGT1A9

2.45e-053100220007669
Pubmed

Genetic polymorphisms of UGT1A8, UGT1A9 and HNF-1α and gastrointestinal symptoms in renal transplant recipients taking mycophenolic acid.

UGT1A8 UGT1A9

2.45e-053100223721685
Pubmed

Functional significance of UDP-glucuronosyltransferase variants in the metabolism of active tamoxifen metabolites.

UGT1A10 UGT1A8

2.45e-053100219244109
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

2.45e-053100210516026
Pubmed

Raloxifene glucuronidation in liver and intestinal microsomes of humans and monkeys: contribution of UGT1A1, UGT1A8 and UGT1A9.

UGT1A8 UGT1A9

2.45e-053100226247833
Pubmed

Different expression of catecholamine transporters in phaeochromocytomas from patients with von Hippel-Lindau syndrome and multiple endocrine neoplasia type 2.

SLC18A1 SLC18A2

2.45e-053100216189177
Pubmed

Enhancement of invasion of hepatocellular carcinoma cells through lysophosphatidic acid receptor.

LPAR3 LPAR2

2.45e-053100223569130
Pubmed

The impact of UGT1A8, UGT1A9, and UGT2B7 genetic polymorphisms on the pharmacokinetic profile of mycophenolic acid after a single oral dose in healthy volunteers.

UGT1A8 UGT1A9

2.45e-053100217339869
Pubmed

Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors.

LPAR3 LPAR2

2.45e-053100212123830
Pubmed

Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling.

LPAR3 LPAR2

2.45e-053100218448840
Pubmed

The vesicular amine transporter family (SLC18): amine/proton antiporters required for vesicular accumulation and regulated exocytotic secretion of monoamines and acetylcholine.

SLC18A1 SLC18A2

2.45e-053100212827358
Pubmed

Differences in UGT1A1, UGT1A7, and UGT1A9 polymorphisms between Uzbek and Japanese populations.

UGT1A7 UGT1A9

2.45e-053100224453052
Pubmed

UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients.

UGT1A8 UGT1A9

2.45e-053100219225446
Pubmed

[Influence of genetic polymorphisms in UGT1A1, UGT1A7 and UGT1A9 on the pharmacokynetics of irinotecan, SN-38 and SN-38G].

UGT1A7 UGT1A9

2.45e-053100223789755
Pubmed

Connexin43, but not connexin30, contributes to adult neurogenesis in the dentate gyrus.

GJB6 GJB1

2.45e-053100228689039
Pubmed

Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture.

LPAR3 LPAR2

2.45e-053100219899077
Pubmed

Lysophosphatidic acid receptor 2/3-mediated IL-8-dependent angiogenesis in cervical cancer cells.

LPAR3 LPAR2

2.45e-053100221964883
Pubmed

Genetic linkage of UGT1A7 and UGT1A9 polymorphisms to UGT1A1*6 is associated with reduced activity for SN-38 in Japanese patients with cancer.

UGT1A7 UGT1A9

2.45e-053100217406868
Pubmed

Ablation of connexin30 in transgenic mice alters expression patterns of connexin26 and connexin32 in glial cells and leptomeninges.

GJB6 GJB1

2.45e-053100222098503
Pubmed

Connexin47 protein phosphorylation and stability in oligodendrocytes depend on expression of Connexin43 protein in astrocytes.

GJB6 GJB1

2.45e-053100223637189
Pubmed

Lysophosphatidic acid receptors.

LPAR3 LPAR2

2.45e-053100211093753
Pubmed

Modulation of the human glucuronosyltransferase UGT1A pathway by splice isoform polypeptides is mediated through protein-protein interactions.

UGT1A8 UGT1A7

2.45e-053100219996319
Pubmed

LPA receptor expression in the central nervous system in health and following injury.

LPAR3 LPAR2

2.45e-053100220495828
Pubmed

Characterization of common UGT1A8, UGT1A9, and UGT2B7 variants with different capacities to inactivate mutagenic 4-hydroxylated metabolites of estradiol and estrone.

UGT1A8 UGT1A9

2.45e-053100216397224
InteractionUGT1A7 interactions

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GLB1L2 RTL9

2.46e-0757936int:UGT1A7
InteractionALDH3B2 interactions

GALT NUBPL SLC18A1 CLN6

4.99e-0625934int:ALDH3B2
InteractionPIGG interactions

NPC1 GPR17 GPR182 ADORA2B LPAR2

9.11e-0661935int:PIGG
InteractionLRP10 interactions

GPR17 GPR182 GOLT1B ADORA2B TSPAN17 LPAR2

1.54e-05115936int:LRP10
InteractionYIPF3 interactions

NPC1 CDS1 PIEZO1 GPR182 SLC35F5 SLC5A5 LPAR2

2.47e-05186937int:YIPF3
InteractionUGT1A9 interactions

UGT1A10 UGT1A7 UGT1A9

2.63e-0513933int:UGT1A9
InteractionUGT1A8 interactions

UGT1A8 UGT1A7

6.30e-053932int:UGT1A8
InteractionABHD12 interactions

RAMP3 UGT1A7 GPR182 UGT1A9 PTCH1

7.84e-0595935int:ABHD12
InteractionATP2A3 interactions

GPR17 PIEZO1 GPR182 GLB1L2 TSPAN17 FAR2 LPAR2

1.00e-04232937int:ATP2A3
Cytoband2q37

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.12e-07319942q37
Cytoband11q25

GLB1L3 GLB1L2

1.45e-032699211q25
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.49e-03226994chr2q37
CytobandEnsembl 112 genes in cytogenetic band chr11q25

GLB1L3 GLB1L2

2.06e-0331992chr11q25
GeneFamilySolute carriers

SLC17A3 SLC1A6 SLC35F5 SLC5A5 SLC6A12 SLC18A1 SLC18A2 SLC23A1 SLC29A4 SLC38A8 SLC23A3

6.18e-083956011752
GeneFamilyUDP glucuronosyltransferases

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.68e-0632604363
GeneFamilyMyosins, class IX

MYO9A MYO9B

1.08e-0526021103
GeneFamilyGap junction proteins

GJB6 GJA9 GJB1

5.12e-0522603314
GeneFamilyLysophosphatidic acid receptors

LPAR3 LPAR2

1.61e-046602205
GeneFamilyG protein-coupled receptors, Class A orphans

GPR17 GPR182 GPR161

2.21e-0378603262
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_200

SLC17A3 UGT1A10 SLC18A1 SLC23A3

3.12e-0542914gudmap_developingKidney_e15.5_Proximal Tubules_200_k5
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#1_top-relative-expression-ranked_200

SLC17A3 UGT1A10 SLC18A1 SLC23A3

3.76e-0544914gudmap_developingKidney_e15.5_early proxim tubul_200_k1
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_200

LPAR3 SLC17A3 UGT1A10 SLC18A1 SLC23A1 SLC23A3

4.74e-05151916gudmap_developingKidney_e15.5_early proxim tubul_200
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RAMP3 DYSF F2RL2 ARFGEF3 FAR2 TLL1 TNFRSF1B

1.55e-0718795703de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 GLB1L2 SLC18A1 APOBEC2 SLC23A1 SLC23A3

1.32e-061629566972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 GLB1L2 SLC18A1 APOBEC2 SLC23A1 SLC23A3

1.64e-0616895635ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 MYO9B MAP3K1 SIGLEC10 TRAF3IP3 TNFRSF1B

4.48e-06200956fd72fe6565e2f4885481991492d58c323ab1ad40
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR182 GSTA3 SLC35F5 SLC6A12 GPR137C

1.35e-051429556a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR182 GSTA3 SLC35F5 SLC6A12 GPR137C

1.35e-05142955671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR182 GSTA3 SLC35F5 SLC6A12 GPR137C

1.35e-051429553557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

GPR182 GSTA3 SLC35F5 SLC6A12 GPR137C

1.35e-05142955a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCellLPS-IL1RA-Myeloid-Monocytes,_Macrophages-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THEMIS2 DDO SLC5A5 AP3B2 SLC23A1

1.44e-051449557c471e332f87d60f4dbed01f3e66bf39995218d0
ToppCellTCGA-Kidney|World / Sample_Type by Project: Shred V9

SLC17A3 UGT1A9 SLC6A12 QRFPR SLC23A3

1.81e-05151955e31974c0d0a0c644205a0ee6013ab74a09d8a306
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 RAMP3 F2RL2 FAR2 LPAR2

2.18e-051579555d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 RAMP3 F2RL2 FAR2 LPAR2

2.18e-05157955ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 GLB1L2 APOBEC2 SLC23A1 SLC23A3

2.94e-05167955ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCelldroplet-Kidney-nan-18m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC17A3 GLB1L2 APOBEC2 SLC23A1 SLC23A3

3.11e-05169955f00741203efa0b948db7223ee8c19bdd0918258a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF QRFPR FAR2 TLL1

3.38e-05172955c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

NPC1 SETD1A SIGLEC10 CLN6 FIGNL1

3.47e-051739554f2843371d18af766c1892529ce286f56c956fde
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA3 GPR17 SSTR1 ADORA2B APOBEC2

3.67e-05175955d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLXNA3 GPR17 SSTR1 ADORA2B APOBEC2

3.67e-051759551d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCelldroplet-Fat-Scat-21m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR17 PTCH1 SLC18A2 TLL1

4.52e-0592954246aebf5f17d50f67a7b48f713ea5043cefefb24
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF QRFPR FAR2 TLL1

4.66e-05184955688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP3 PIEZO1 GPR182 DYSF TLL1

4.66e-051849553b0389c3a5a16697de860e98ebc48ed39ede646f
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAMP3 DDO SLC1A6 SLC38A8

4.72e-059395493a8d3ad978e4cd450f7a69a4cbac1a59038e80d
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GPR182 DDO DYSF F2RL2 TNFRSF1B

5.16e-05188955b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CDS1 MYO9A MAP3K1 SLC35F5 SLC6A12

5.29e-05189955904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAMP3 GPR182 DYSF MAP3K1 TLL1

5.43e-05190955b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCelldroplet-Fat-Scat-21m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR17 PTCH1 SLC18A2 TLL1

5.56e-0597954440d45ecfc9b66cb61d734118601e745892d51e3
ToppCelldroplet-Fat-Scat-21m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR17 PTCH1 SLC18A2 TLL1

5.56e-05979546fff45d4c4bbd81a67e1ad12b131cfe6a5ab37e6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF QRFPR FAR2 TLL1

5.56e-05191955f663131a4810584c5854bd64ee7991a237b7707f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 MYO9A MAP3K1 SLC35F5 SLC6A12

5.56e-05191955d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellLPS-IL1RA-Endothelial-Endothelial-Vein|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAMP3 GPR182 QRFPR FAR2 TLL1

5.70e-05192955717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF FAR2 TLL1 TNFRSF1B

5.84e-05193955287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF QRFPR FAR2 TLL1

5.99e-05194955b490fffc94f005dff9a34ce34d80ca776e3a1387
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF QRFPR FAR2 TLL1

5.99e-05194955ad6c04ad0621689e3bf4c94ccd6e60653bbd02c7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

RAMP3 DYSF QRFPR FAR2 TLL1

5.99e-05194955fa6d51f36a3dae8763a595c20892987ed454c0f0
ToppCellPCW_05-06-Endothelial-Endothelial_mature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RAMP3 DYSF F2RL2 FAR2 TNFRSF1B

6.14e-0519595554fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCellCOVID-19-kidney-VWF+PLVAP+VCAM1+EC|kidney / Disease (COVID-19 only), tissue and cell type

RAMP3 GPR182 DYSF FAR2 TLL1

6.29e-05196955ac2c4a325efa8497a755cd31fb6a9d94d8e3bf42
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAMP3 PIEZO1 GPR182 DYSF TLL1

6.29e-0519695509a7edf4a7defb7fe70d9777dd9500ee8421ff31
ToppCellTracheal-NucSeq-Endothelial-Endothelia_lymphatic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RAMP3 PIEZO1 GPR182 DYSF TLL1

6.29e-05196955e50d2c66d5c5cd25fdfecdcc4c8506a1d0a85755
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

RAMP3 DYSF ARFGEF3 FAR2 TLL1

6.29e-0519695581278e696d823744267d6315c4d42799c4ea0b2c
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

THEMIS2 MYO9B DYSF MAP3K1 TNFRSF1B

6.44e-05197955a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_venous_(4)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RAMP3 DYSF ARFGEF3 FAR2 TLL1

6.44e-0519795588859b7b24b36afab4a684fd7abf0e0f8e5b525c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THEMIS2 MYO9B FAR2 SIGLEC10 TNFRSF1B

6.44e-05197955d95565652ca318a2298d6918d54ba6367e9560f4
ToppCelldistal-Hematologic-Nonclassical_Monocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

THEMIS2 MAP3K1 SIGLEC10 TRAF3IP3 TNFRSF1B

6.44e-05197955e817c1a8549e403e723b1b6c73cdb04f1179909d
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Mesenchymal-Cilia-bearing_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

LPAR3 MARVELD1 DDO GLB1L2 GSTA3

6.75e-051999552d8ab4aee300c7c4baf662940ce855da2b6d2cae
ToppCellParenchymal-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD16|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS2 MAP3K1 SIGLEC10 TRAF3IP3 TNFRSF1B

6.75e-05199955ac866ae110967c5867ff4601939b79861d43df54
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR3 CDS1 GJB6 GRM3 ADORA2B

6.92e-0520095507d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR3 CDS1 GJB6 GRM3 ADORA2B

6.92e-05200955d0812817ef99608994193787a62d39adeb2070ca
ToppCellLPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|LPS_only / Treatment groups by lineage, cell group, cell type

FAR2 NT5DC2 TRAF3IP3 FIGNL1 SLC38A8

6.92e-05200955afbbfe0b8e66df36c244935182cb26feeb31a085
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR3 CDS1 GJB6 GRM3 ADORA2B

6.92e-05200955cd54ddf1919c98e84b7e4aba85b374fc8b407206
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC17A3 SLC6A12 QRFPR SLC38A8

7.03e-05103954eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Keratinizing_Cervical_Squamous_Cell_Carcinoma-2|TCGA-Cervix / Sample_Type by Project: Shred V9

UGT1A7 UGT1A9 PTCH1 RTL9

7.30e-0510495457d2a707aacaa90f92895b87f4ecf87b7451d667
Drugnaringenin chalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.36e-095944ctd:C027329
Druganthrarobin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.36e-095944ctd:C032186
Drug1,2,5,8-tetrahydroxy anthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.06e-096944ctd:C543211
Drugalloin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.06e-096944ctd:C006457
Drug2',5'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.06e-096944ctd:C107497
Drugbevirimat

ERVK-6 UGT1A10 UGT1A8 UGT1A7 UGT1A9 TNFRSF1B

7.43e-0936946CID000457928
Drug2',4'-dihydroxychalcone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

9.44e-097944ctd:C059354
Drug1,4-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.88e-088944ctd:C034890
DrugAC1MRQNQ

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.38e-089944CID003522271
DrugDHPASiU

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.38e-089944CID000197602
Drug3-iodophenol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.38e-089944CID000012272
DrugAC1L4J7U

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.38e-089944CID000186631
DrugChebi:32663

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.38e-089944CID005460873
Drug2,6-dihydroxyanthraquinone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.61e-0810944ctd:C034889
Drug4-nitrophenyl)imidazole

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.79e-0811944CID000123155
DrugAC1O5XMV

UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.79e-0811944CID006442661
Drug2-hydroxyamino-1-methyl-6-phenylimidazo(4,5-b)pyridine

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

1.18e-0729945ctd:C060533
DrugN-OH-DABZ

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-0712944CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-0712944CID000088735
Drug4-hydroxyestrone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-0712944ctd:C026418
Drug2,4,6-TCB

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-0712944CID000037247
Drugnonanoyl-N-methylglucamide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-0712944CID000160090
Drug7,7,7-triphenylheptanoic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.31e-0712944CID000276709
Drugparicalcitol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 MAP3K1

1.41e-0730945CID005281104
Drug4-ethylphenol

UGT1A10 UGT1A8 UGT1A7 UGT1A9 DDO

1.68e-0731945CID000031242
Drug2-hydroxyestrone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.89e-0713944ctd:C024980
Drugtritanol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.89e-0713944CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.89e-0713944CID003081279
Drugcotinine-N-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.89e-0713944CID000000411
Drugalizarin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.89e-0713944ctd:C010078
DrugR(-)-Denopamine

CDS1 UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.33e-0733945CID000003818
Drugarabinosyluracil

ERVK-6 GALT UGT1A10 UGT1A8 UGT1A7 UGT1A9 PRPF8 DERA ADORA2B APOBEC2 SLC29A4

2.40e-073549411CID000001177
Drugpropranolol glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.64e-0714944CID000119515
DrugPCB-61

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.64e-0714944CID000036401
Drughydratropic acid

UGT1A10 UGT1A8 UGT1A7

2.72e-074943ctd:C013025
Drug2-vanillin

UGT1A10 UGT1A8 UGT1A7

2.72e-074943ctd:C060843
Drugdiphenylacetic acid

UGT1A10 UGT1A8 UGT1A7

2.72e-074943ctd:C037760
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-0715944CID000040469
Drugafloqualone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-0715944CID000002040
Drugnaphthyl sulphate

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-0715944CID000114775
Drugcoumarin-3-carboxylic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-0715944CID000010752
Drugbergamottin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-0715944ctd:C068337
Drugsulforaphane nitrile

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.59e-0715944CID000543743
Drugglucoraphanin

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

3.67e-0736945CID000656556
DrugAC1L9DGV

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

3.67e-0736945CID000417381
Drugquercetin-3,4'-diglucoside

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.77e-0716944CID005320835
Drug1'-hydroxyestragole

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.77e-0716944CID000040003
Drugbilirubin-phosphate

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.77e-0716944CID005497144
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.22e-0717944CID000003573
Drug6-hydroxychrysene

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.22e-0717944CID000037766
Drugatazanavir

NELFCD MYO9B UGT1A10 UGT1A8 UGT1A7 UGT1A9 ITGAD

6.64e-07120947CID000148192
Drugisovaleric acid

UGT1A10 UGT1A8 UGT1A7

6.77e-075943ctd:C008216
Drugbiphenylylacetic acid

UGT1A10 UGT1A8 UGT1A7

6.77e-075943ctd:C012776
DrugSureCN12722713

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID005488034
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID000152226
DrugBr 2

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID003060900
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID000036614
DrugApApG

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID003081975
DrugC1 11-32

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID000443077
DrugC11131

UGT1A10 UGT1A8 UGT1A7 UGT1A9

7.97e-0718944CID000443076
DrugAC1NFJIQ

CDS1 UGT1A10 UGT1A8 UGT1A7 UGT1A9

8.12e-0742945CID004659568
Drug9-OH-risperidone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.01e-0619944CID000475100
Drug5alpha-spirostan-3beta-ol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.01e-0619944CID000091433
Drugalmokalant

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.01e-0619944CID003033962
DrugMS-222

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

1.03e-0644945CID000011400
Drugtectochrysin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.25e-0620944CID005281954
DrugAC1L1OBF

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.25e-0620944CID000032736
Drug4'-hydroxydiclofenac

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.25e-0620944CID000116545
Drugentacapone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.25e-0620944ctd:C071192
Drug3-phenylpropionic acid

UGT1A10 UGT1A8 UGT1A7

1.35e-066943ctd:C035253
DrugIndoprofen

UGT1A10 UGT1A8 UGT1A7

1.35e-066943ctd:D007216
Drugestriol-16-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.55e-0621944CID000122281
Drugdulcin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.55e-0621944CID000009013
DrugBenzamidoxime hydrochloride

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.55e-0621944CID000069186
Drugsalicylamide

UGT1A10 UGT1A8 UGT1A7 UGT1A9 G6PD

1.60e-0648945CID000005147
Drugretigabine

UGT1A10 UGT1A8 UGT1A7 GPR182 UGT1A9

1.60e-0648945CID000121892
Drugamitriptyline

HTR5A UGT1A10 UGT1A8 UGT1A7 UGT1A9 DYSF ADORA2B

1.87e-06140947CID000002160
Drugamonafide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.88e-0622944CID000050515
DrugN-methylpiperazine

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.88e-0622944CID000053167
Drugplumbagin

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.88e-0622944ctd:C014758
Drugphenanthroline

UGT1A10 UGT1A8 UGT1A7 UGT1A9 GSTA3

1.97e-0650945CID000067473
Drug(+/-)-Abacavir

UGT1A10 UGT1A8 UGT1A7 UGT1A9 TNFRSF1B

2.18e-0651945CID000001971
DrugH944

UGT1A10 UGT1A8 UGT1A7 GPR182 UGT1A9 TNFRSF1B

2.26e-0692946CID000004271
Drugamidoxime

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.27e-0623944CID000465967
Drugestradiol-3-glucuronide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.27e-0623944CID000066651
Drugphenanthridine

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.27e-0623944CID000009189
DrugAC1Q5UBL

PTCH1 GRM3 ADORA2B SLC6A12 SLC18A1 SLC18A2 G6PD

2.48e-06146947CID000005466
DrugAS-3201

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.72e-0624944CID000153948
Drug5-MOP

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.22e-0625944CID000002355
DrugHymecromone

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.22e-0625944ctd:D006923
DrugAzMC

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.22e-0625944CID000064986
DrugN-acetylbenzidine

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.22e-0625944CID000018787
Drug5,6-benzoquinoline

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.22e-0625944CID000006796
DrugN-phenylmaleimide

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.22e-0625944CID000013662
DrugInvader

UGT1A10 UGT1A8 UGT1A7 UGT1A9 SLC5A5

3.48e-0656945CID006442259
Drugglabridin

UGT1A10 UGT1A8 UGT1A9

3.76e-068943ctd:C107601
DrugThymol

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.80e-0626944ctd:D013943
Drugnorclozapine

HTR5A UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.81e-0657945CID000002820
Drug3-hydroxyandrostan-17-one

UGT1A10 UGT1A8 UGT1A7 UGT1A9 G6PD SLC29A4

4.13e-06102946CID000000225
Druglicochalcone A

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.45e-0627944ctd:C070840
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.61e-105934EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.61e-105934EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.61e-105934EFO_0801853
DiseaseX-21339 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.21e-097934EFO_0800808
DiseaseX-11793--oxidized bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0021260
DiseaseSuccinimide measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0022118
DiseaseX-11530 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0800696
DiseaseX-10458 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0800692
DiseaseX-24849 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0600043
Diseaseplasma clozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0802740
DiseaseX-16946 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.41e-098934EFO_0800766
DiseaseX-11442 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0021236
DiseaseX-11441 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0801036
DiseaseX-11880 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0800698
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0004570, GO_0009410
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.15e-089934EFO_0020691
DiseaseX-21448 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.91e-0810934EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.91e-0810934EFO_0802185
DiseaseX-23974 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.91e-0810934EFO_0800867
Diseasebilirubin measurement, response to tenofovir

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.91e-0810934EFO_0004570, EFO_0009279
DiseaseX-21796 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0811934EFO_0800825
Diseasepregnenetriol sulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0811934EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0811934EFO_0600039
Diseaseinsomnia, bilirubin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0811934EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0811934EFO_0800972
Diseasealdosterone measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.00e-0811934EFO_0010219
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A10 UGT1A8 UGT1A9

3.03e-083933EFO_0022216
Diseaseindole-3-carboxylate measurement

UGT1A10 UGT1A8 UGT1A9

3.03e-083933EFO_0800043
Diseasexanthurenate measurement

SLC17A3 UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.12e-0829935EFO_0010551
Diseasebiliverdin measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.49e-0812934EFO_0021033
Diseasep-cresol glucuronide measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

4.49e-0812934EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.47e-0813934EFO_0802007
Diseasepregnenetriol disulfate measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

6.47e-0813934EFO_0800587
DiseaseX-21441 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.13e-0717934EFO_0800814
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.13e-0717934EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.74e-0718934EFO_0801382
Diseasetissue factor measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.31e-0721934EFO_0010623
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A10 UGT1A8 UGT1A9

6.02e-076933EFO_0800566
Diseaseneuroblastoma, cutaneous melanoma

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.79e-0628934EFO_0000389, EFO_0000621
Diseaseresponse to dolutegravir

UGT1A10 UGT1A8 UGT1A7 UGT1A9

2.38e-0630934EFO_0600017
Diseaseindoleacetate measurement

UGT1A10 UGT1A8 UGT1A9

3.58e-0610933EFO_0021015
DiseaseSchizophrenia

SETD1A HTR5A MYO9B DDO GRM3 SLC1A6 SLC6A12 SLC18A1 SLC18A2 PDIK1L ERVK-8 TNFRSF1B SLC23A3

4.03e-068839313C0036341
Diseasevitamin D deficiency

UGT1A10 UGT1A8 UGT1A7 UGT1A9

5.64e-0637934EFO_0003762
DiseaseX-24588 measurement

UGT1A10 UGT1A8 UGT1A9

8.47e-0613933EFO_0800898
Diseasebilirubin measurement

MYO9B UGT1A10 UGT1A8 UGT1A7 PIEZO1 UGT1A9 GOLT1B TLL1 G6PD

1.11e-05442939EFO_0004570
Diseasevitamin D measurement, COVID-19

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.76e-0549934EFO_0004631, MONDO_0100096
Diseasegallstones

UGT1A10 UGT1A8 UGT1A7 RMI2 UGT1A9

2.41e-05108935EFO_0004210
Diseasecocaine abuse (implicated_via_orthology)

SLC18A1 SLC18A2

2.94e-053932DOID:809 (implicated_via_orthology)
Diseaseurate measurement, spine bone mineral density

UGT1A10 UGT1A8 UGT1A7 UGT1A9

3.44e-0558934EFO_0004531, EFO_0007701
Diseasetartronate (hydroxymalonate) measurement

SLC23A1 SLC23A3

5.87e-054932EFO_0800944
Diseasemetabolite measurement

SETD1A SLC17A3 GLB1L3 UGT1A10 UGT1A8 UGT1A7 UGT1A9 SLC6A12 G6PD

7.01e-05560939EFO_0004725
Diseasethyroxine measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.40e-0483934EFO_0005130
Diseaseamphetamine abuse (implicated_via_orthology)

SLC18A1 SLC18A2

1.46e-046932DOID:670 (implicated_via_orthology)
Diseasehormone measurement

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.47e-0484934EFO_0004730
Diseasecholelithiasis

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.76e-0488934EFO_0004799
Diseaseimmature platelet count

NELFCD DDO STK35 FAR2

3.59e-04106934EFO_0803544
Diseasethreonate measurement

SLC23A1 SLC23A3

4.35e-0410932EFO_0021032
Diseaseurinary bladder carcinoma

HTR5A UGT1A10 UGT1A8

4.44e-0447933MONDO_0004986
Diseasehemolysis

MYO9B PIEZO1 G6PD

4.44e-0447933EFO_0009473
Diseaseimmature platelet fraction

NELFCD MYO9B DDO FAR2

4.73e-04114934EFO_0009187
Diseasedodecanedioate measurement

UGT1A10 UGT1A8

6.35e-0412932EFO_0021054
Diseaseplatelet component distribution width

NPC1 THEMIS2 CAPN12 NELFCD MYO9B RMI2 DDO FAR2 BRAT1

6.36e-04755939EFO_0007984
Diseaseascorbic acid 3-sulfate measurement

SLC23A1 SLC23A3

8.72e-0414932EFO_0800173
Diseaseglycerate measurement

SLC23A1 SLC23A3

1.00e-0315932EFO_0021029
Diseasevitamin C measurement

SLC23A1 SLC23A3

1.15e-0316932EFO_0600003
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A10 UGT1A8 UGT1A7 UGT1A9

1.22e-03147934DOID:9352 (biomarker_via_orthology)
Diseasemuscular dystrophy (is_implicated_in)

POMT1 DYSF

1.30e-0317932DOID:9884 (is_implicated_in)
Diseasetemporal horn of lateral ventricle volume measurement

UGT1A10 UGT1A8 QRFPR

1.54e-0372933EFO_0010333
Diseasereticulocyte count

MYO9B PIEZO1 RMI2 EXOSC3 DNAAF9 ITGAD PRPF8 MAP3K1 NT5DC2 SLC23A1

1.68e-0310459310EFO_0007986
DiseaseArthrogryposis

MYO9A DYNC1H1

1.98e-0321932C0003886

Protein segments in the cluster

PeptideGeneStartEntry
FVENVEWRVLGMPAR

CHRNA10

196

Q9GZZ6
GFPRRAVMQVFTEWL

BRAT1

606

Q6PJG6
LVRAREGVWIPVSMD

ERVK-19

426

O71037
LVRAREGVWIPVSMD

ERVK-8

426

Q902F8
RDWMLAVLAFPVGVF

AIG1

86

Q9NVV5
VIQNLFEGMIWFLVP

CDS1

231

Q92903
LAMIVGIFALCWLPV

ADORA2B

236

P29275
PLMLIAGIVICAFWV

ACVR2A

146

P27037
VMVSVWLILEAPGTR

GRM3

701

Q14832
AFLWVVVAVAMAPLL

GPR17

181

Q13304
TLWALVFLGILVGMV

FGF6

21

P10767
RAVTPEMRALVVDWL

CCNP

101

Q9H8S5
VGRLFMWEEPEIQAA

APOBEC2

151

Q9Y235
QVPMARASILWLIGE

AP3B2

496

Q13367
PVVLTVAMAGLVVWR

RAMP3

126

O60896
DMFLSVIGQRWPIDV

PAPPA-AS1

56

Q5QFB9
RAFTMLGVVWLVAVI

QRFPR

161

Q96P65
LMVLRFANRIFGPIW

G6PD

211

P11413
IPVDTVVNLMLAVGW

FAR2

276

Q96K12
IVVWPMLRPDIFTGL

FIGNL1

416

Q6PIW4
LLSALPFIVAWVIGM

SLC17A3

256

O00476
FVVLIGWPLIGMIFE

GOLT1B

76

Q9Y3E0
RGRVVMLIVGVWVAA

LPAR2

141

Q9HBW0
QCIRFPVVAMGVLKW

NELFCD

416

Q8IXH7
VLVVMVVAFAVLWLP

NPY4R

266

P50391
FVLMAAEIGLWVILR

GLB1L3

146

Q8NCI6
PRVIWYRGGLEMILA

HMCN2

726

Q8NDA2
IVFGMVLFLWEHVPA

GPR137C

301

Q8N3F9
MEPIRWLLAAAGVEF

GSTA3

16

Q16772
RQPVMVLVGGLEFWL

PLXNA3

1191

P51805
VHPEWRRAGIATFMI

KAT14

706

Q9H8E8
LVWAIAIFMGAVPTL

LPAR3

151

Q9UBY5
LVRAREGVWIPVSMD

ERVK-7

1186

P63135
VPFWADVVLGFRKMT

DDO

106

Q99489
VVGVPANAVTLWMLF

F2RL2

106

O00254
PVLLNGVAVWDVVME

ITGAD

971

Q13349
KDWMRPIVIAIFVGV

NPC1

831

O15118
MWGFLKRPVVVTADI

POMT1

1

Q9Y6A1
FGRWMDVVVDDRLPV

CAPN12

146

Q6ZSI9
PVLMLYRLWEEGIVA

LACTBL1

86

A8MY62
PGILRWFEVKSVFMV

DOCK1

1471

Q14185
LVRAREGVWIPVSMD

ERVK-25

426

P61570
LVRAREGVWIPVSMD

ERVK-6

426

Q69384
IFRMLVLGVAAEDVW

GJA9

31

P57773
LMSVPEIRAVVDAWA

GALT

141

P07902
VLVTAGPVFTEEMWR

ARFGEF3

1591

Q5TH69
FRVMILVVAAQEVWG

GJB6

31

O95452
LMVQICVWFGRPLEK

DNAAF9

971

Q5TEA3
MVGILIGVFVLCWIP

HTR5A

286

P47898
EAIMRLVGIIIWYAP

SLC1A6

301

P48664
GRVWLSVIFIFRIMV

GJB1

21

P08034
FRIMVLVVAAESVWG

GJB1

31

P08034
LVPVLGSRWLMVNVA

MARVELD1

86

Q9BSK0
PREMTRWVRGIFEAL

DYNC1H1

2796

Q14204
TILVVLGAFMVTWGP

GPR161

271

Q8N6U8
VLMAAEIGLWVILRP

GLB1L2

121

Q8IW92
LVRAREGVWIPVSMD

HERVK_113

426

Q902F9
PVAIVMLRAIRDFFW

DERA

231

Q9Y315
ARMPVQIRVKLWFGL

DYSF

846

O75923
PLEIVFGMNGRIWVK

EXOSC3

226

Q9NQT5
FLVEESEPVVWRGLM

NUBPL

146

Q8TB37
EWVIFIMGGLILVIP

OR1E1

196

P30953
LAEPWIQVFGMELVG

MAP3K1

556

Q13233
LWDIIFMDGIPDVFR

FAN1

846

Q9Y2M0
AAERWFILQMEVGEP

RTL9

1196

Q8NET4
LMPEPAQRWLVGFVL

SSTR1

211

P30872
GPLDLAAVWMQGRVV

RMI2

51

Q96E14
NWDPVMVGIRRIFAF

SLC35F5

476

Q8WV83
LSPRMLVWLVASGIV

TLL1

6

O43897
AIADLGIVLSLPVWM

GPR182

96

O15218
FALGIIIWAMLERIT

PDIK1L

241

Q8N165
SPVMEFWERRVLGIT

SLC6A12

186

P48065
FLLNPWTAGIIVMVL

PTCH1

1046

Q13635
PIVLFLGRSVMQDFW

SLC38A8

311

A6NNN8
PATGRWRMLLIVVSV

CNEP1R1

26

Q8N9A8
RIHEWGLFAMEPIAA

SETD1A

1576

O15047
IVGFSIFMALLLPRW

SLC23A3

456

Q6PIS1
WVLDFGRPIAMLVFP

CLN6

56

Q9NWW5
VAAIAMARIIDLVPW

TEPP

51

Q6URK8
VWLFFMRGITPLLER

PRPF8

636

Q6P2Q9
RWLPVLMVVIAAALA

TRAF3IP3

526

Q9Y228
DIFALGIIIWAMIER

STK35

436

Q8TDR2
LDPVWLFVVVGGVMS

TSPAN17

61

Q96FV3
PLDLAVFWVEFVMRH

UGT1A10

451

Q9HAW8
DARGDIMAIAPWIRI

SLC23A1

291

Q9UHI7
VVMLSGFWVVLARGV

SLC5A5

196

Q92911
VEIMPEWVFVGLVLL

ILDR2

181

Q71H61
MCFEIPPRWLDLTVV

THEMIS2

496

Q5TEJ8
WSIRTALLAIIGFMP

UBE2J1

106

Q9Y385
VLVVMVVAFAVLWLP

NPY4R2

266

P0DQD5
HMVGPDWRQLFDVVI

NT5DC2

281

Q9H857
PLDLAVFWVEFVMRH

UGT1A9

451

O60656
CILGEWLPILIMAVF

SLC29A4

381

Q7RTT9
MAPVAVWAALAVGLE

TNFRSF1B

1

P20333
LVPFLVELRAVMDWV

PIEZO1

2111

Q92508
FWIRVQESVMVPEGL

SIGLEC10

21

Q96LC7
AIGFPWLMTIIGIID

SLC18A2

446

Q05940
WLMTIIGIIDILFAP

SLC18A2

451

Q05940
PLDLAVFWVEFVMRH

UGT1A7

451

Q9HAW7
PLDLAVFWVEFVMRH

UGT1A8

451

Q9HAW9
GFPWLMVITGVINIV

SLC18A1

456

P54219
LVIWNVILRFMGDLP

MYO7B

1011

Q6PIF6
MIGIDPVAVFRWAIL

MYO9A

691

B2RTY4
VRELIGMDPVAVFRW

MYO9B

671

Q13459
GMDPVAVFRWAVLRA

MYO9B

676

Q13459