Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction5-diphosphoinositol pentakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

5.38e-0521472GO:0033857
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

BRIP1 POP4 CARS1 DDX56 ZNFX1 TARS2 FANCM TRMU SARS2 MLH1 DNA2 TATDN1 DHX29 GEN1 TGS1

8.51e-0564514715GO:0140640
GeneOntologyMolecularFunctioninositol hexakisphosphate 3-kinase activity

PPIP5K1 PPIP5K2

3.20e-0441472GO:0052724
GeneOntologyMolecularFunctioninositol hexakisphosphate 1-kinase activity

PPIP5K1 PPIP5K2

3.20e-0441472GO:0052723
GeneOntologyMolecularFunctiondiphosphoinositol pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

5.31e-0451472GO:0000829
GeneOntologyMolecularFunctioninositol hexakisphosphate kinase activity

PPIP5K1 PPIP5K2

5.31e-0451472GO:0000828
GeneOntologyMolecularFunctioninositol-1,3,4,5,6-pentakisphosphate kinase activity

PPIP5K1 PPIP5K2

5.31e-0451472GO:0000827
GeneOntologyMolecularFunctioninositol hexakisphosphate 5-kinase activity

PPIP5K1 PPIP5K2

5.31e-0451472GO:0000832
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

BRIP1 POP4 CARS1 DDX56 TARS2 FANCM TRMU SARS2 DHX29 TGS1

1.06e-0341714710GO:0140098
GeneOntologyMolecularFunctioncAMP-dependent protein kinase activity

PRKACA PRKACG

1.10e-0371472GO:0004691
GeneOntologyMolecularFunction5'-flap endonuclease activity

DNA2 GEN1

1.10e-0371472GO:0017108
GeneOntologyMolecularFunctionhelicase activity

BRIP1 DDX56 ZNFX1 FANCM DNA2 DHX29

1.13e-031581476GO:0004386
GeneOntologyBiologicalProcessneuron projection development

HECW1 MYO5B KALRN DOCK10 SEMA5A DDX56 WLS LGALS1 IGFALS DST ALMS1 SEMA5B HECW2 MYPN STAU2 FSHR TRPV2 SLITRK5 MTR LRRC7 DLX5 EIF2AK4 LGR6 IKBKB FKBP4

3.68e-06128514625GO:0031175
GeneOntologyBiologicalProcessneuron development

HECW1 MYO5B KALRN DOCK10 SEMA5A DDX56 WLS LGALS1 IGFALS DST ALMS1 SEMA5B HECW2 MYPN STAU2 FSHR TRPV2 SLITRK5 MTR LRRC7 DLX5 EIF2AK4 LGR6 IKBKB FKBP4

3.37e-05146314625GO:0048666
GeneOntologyBiologicalProcessneuron projection morphogenesis

HECW1 MYO5B KALRN DOCK10 SEMA5A WLS IGFALS DST SEMA5B HECW2 MYPN STAU2 TRPV2 SLITRK5 DLX5 EIF2AK4 LGR6

5.45e-0580214617GO:0048812
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

HECW1 MYO5B KALRN DOCK10 SEMA5A WLS IGFALS DST SEMA5B HECW2 MYPN STAU2 TRPV2 SLITRK5 DLX5 EIF2AK4 LGR6

7.05e-0581914617GO:0120039
GeneOntologyBiologicalProcesscell projection morphogenesis

HECW1 MYO5B KALRN DOCK10 SEMA5A WLS IGFALS DST SEMA5B HECW2 MYPN STAU2 TRPV2 SLITRK5 DLX5 EIF2AK4 LGR6

7.83e-0582614617GO:0048858
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

HECW1 MYO5B KALRN DOCK10 SEMA5A WLS IGFALS DST SEMA5B HECW2 MYPN STAU2 TRPV2 SLITRK5 DLX5 LGR6

8.23e-0574814616GO:0048667
GeneOntologyBiologicalProcessdendrite morphogenesis

HECW1 MYO5B KALRN DOCK10 WLS HECW2 STAU2 SLITRK5

8.52e-051981468GO:0048813
GeneOntologyBiologicalProcessregulation of dendrite morphogenesis

HECW1 MYO5B KALRN WLS HECW2 STAU2

9.23e-051031466GO:0048814
HumanPhenoPyridoxine-responsive sideroblastic anemia

BRIP1 FANCM FANCD2 FANCG FANCI

4.23e-0623575HP:0005522
HumanPhenoAbsent testis

BRIP1 FANCM FANCD2 FANCG FANCI

6.57e-0625575HP:0010469
HumanPhenoAplasia/Hypoplasia of the uvula

BRIP1 FANCM FANCD2 FANCG FANCI

1.19e-0528575HP:0010293
HumanPhenoDuodenal stenosis

BRIP1 FANCM FANCD2 FANCG FANCI

1.42e-0529575HP:0100867
HumanPhenoSmall intestinal stenosis

BRIP1 FANCM FANCD2 FANCG FANCI

1.42e-0529575HP:0012848
HumanPhenoClubbing of toes

BRIP1 FANCM FANCD2 FANCG FANCI

1.69e-0530575HP:0100760
HumanPhenoMeckel diverticulum

BRIP1 FANCM FANCD2 FANCG FANCI

2.00e-0531575HP:0002245
HumanPhenoHypoplasia of the ulna

BRIP1 FANCM GSC FANCD2 FANCG FANCI

2.85e-0555576HP:0003022
HumanPhenoSideroblastic anemia

BRIP1 FANCM FANCD2 FANCG FANCI

3.69e-0535575HP:0001924
HumanPhenoAbnormal preputium morphology

BRIP1 FANCM FANCD2 FANCG FANCI

4.25e-0536575HP:0100587
HumanPhenoAplasia/Hypoplasia of the ulna

BRIP1 FANCM GSC FANCD2 FANCG FANCI

4.71e-0560576HP:0006495
HumanPhenoMultiple cafe-au-lait spots

BRIP1 FANCM FANCD2 FANCG FANCI MLH1

6.82e-0564576HP:0007565
HumanPhenoAbnormal ileum morphology

BRIP1 FANCM FANCD2 FANCG FANCI

1.02e-0443575HP:0001549
HumanPhenoTriphalangeal thumb

BRIP1 FANCM FANCD2 FANCG FANCI DLX5

1.23e-0471576HP:0001199
HumanPhenoAccessory phalanx of the thumb

BRIP1 FANCM FANCD2 FANCG FANCI DLX5

1.23e-0471576HP:0009619
HumanPhenoForearm undergrowth

BRIP1 FANCM GSC FANCD2 FANCG FANCI

1.67e-0475576HP:0009821
HumanPhenoHydroureter

BRIP1 FANCM FANCD2 FANCG FANCI PRKACA

1.93e-0477576HP:0000072
HumanPhenoHigh palate

TLK2 BRIP1 IPO8 STAG1 GNE CARS1 SEMA5A FANCM WLS GSC FANCD2 TRMU FANCG DST FANCI PIK3R1 HECW2 MYPN CLTC PLCH1

2.19e-047945720HP:0000218
HumanPhenoClubbing

BRIP1 CARS1 FANCM FANCD2 FANCG FANCI EIF2AK4 HYDIN

2.50e-04152578HP:0001217
HumanPhenoBicornuate uterus

BRIP1 FANCM FANCD2 FANCG FANCI

2.55e-0452575HP:0000813
HumanPhenoLow weight

UBR1 BRIP1 STAG1 CARS1 IRF5 RRM1 FANCM FANCD2 FANCG GUF1 FANCI PIK3R1 NCAPD2 MLH1 DNA2 PPP2R3C MCTP2

3.28e-046275717HP:0001823
HumanPhenoAbnormality of chromosome stability

BRIP1 FANCM FANCD2 FANCG FANCI

3.33e-0455575HP:0003220
HumanPhenoUpper limb undergrowth

BRIP1 FANCM GSC FANCD2 FANCG FANCI

3.54e-0486576HP:0009824
HumanPhenoAbnormal duodenum morphology

BRIP1 IPO8 FANCM FANCD2 FANCG FANCI

4.01e-0488576HP:0002246
HumanPhenoLocalized skin lesion

UBR1 TRAF6 BRIP1 IPO8 SEMA5A IRF5 IDH2 FANCM WLS GSC FANCD2 FANCG DST GNA14 FANCI PIK3R1 MLH1 TRPV3 EIF2AK4 GRHL3 MCTP2

4.03e-048975721HP:0011355
MousePhenoincreased cellular sensitivity to DNA damaging agents

BRIP1 FANCM FANCD2 FANCI VCPIP1

2.44e-06261205MP:0014040
DomainLRR_1

KERA LRRC70 ERBIN IGFALS PRELP FSHR ANP32A SLITRK5 PHLPP1 LRRC7 LGR6

1.31e-0621914711PF00560
DomainLRRNT

KERA IGFALS PRELP FSHR SLITRK5 LGR6

3.63e-06531476PF01462
DomainLRR

KERA LRRC70 ERBIN IGFALS PRELP ANP32A SLITRK5 PHLPP1 LRRC7 LGR6

4.40e-0620114710PS51450
DomainLRR_8

KERA LRRC70 ERBIN IGFALS PRELP SLITRK5 PHLPP1 LRRC7 LGR6

8.55e-061711479PF13855
DomainLeu-rich_rpt

KERA LRRC70 ERBIN IGFALS PRELP FSHR ANP32A SLITRK5 PHLPP1 LRRC7 LGR6

1.02e-0527114711IPR001611
DomainLRR_TYP

KERA LRRC70 ERBIN IGFALS PRELP SLITRK5 PHLPP1 LRRC7 LGR6

1.13e-051771479SM00369
DomainLeu-rich_rpt_typical-subtyp

KERA LRRC70 ERBIN IGFALS PRELP SLITRK5 PHLPP1 LRRC7 LGR6

1.13e-051771479IPR003591
DomainLRRNT

KERA LRRC70 IGFALS PRELP FSHR SLITRK5 LGR6

1.23e-05981477IPR000372
DomainLRRNT

KERA LRRC70 IGFALS PRELP FSHR SLITRK5 LGR6

1.23e-05981477SM00013
DomainWW

TCERG1L HECW1 TCERG1 HECW2 UTRN

3.32e-05471475PF00397
DomainWW

TCERG1L HECW1 TCERG1 HECW2 UTRN

3.68e-05481475SM00456
Domain-

KERA LRRC70 ERBIN IGFALS PRELP FSHR ANP32A SLITRK5 PHLPP1 LRRC7 LGR6

4.83e-05321147113.80.10.10
DomainWW_DOMAIN_1

TCERG1L HECW1 TCERG1 HECW2 UTRN

4.95e-05511475PS01159
DomainWW_DOMAIN_2

TCERG1L HECW1 TCERG1 HECW2 UTRN

4.95e-05511475PS50020
DomainWW_dom

TCERG1L HECW1 TCERG1 HECW2 UTRN

5.44e-05521475IPR001202
DomainL_dom-like

KERA LRRC70 ERBIN IGFALS PRELP FSHR ANP32A SLITRK5 PHLPP1 LRRC7 LGR6

5.87e-0532814711IPR032675
DomainHECW_N

HECW1 HECW2

6.15e-0521472IPR032348
DomainHECW_N

HECW1 HECW2

6.15e-0521472PF16562
Domainaa-tRNA-synt_IIb

TARS2 SARS2 EIF2AK4

7.53e-05111473IPR002314
DomaintRNA-synt_2b

TARS2 SARS2 EIF2AK4

7.53e-05111473PF00587
DomainDistal-less_N

DLX2 DLX5

1.84e-0431472IPR022135
DomainDLL_N

DLX2 DLX5

1.84e-0431472PF12413
Domainaa-tRNA-synth_II

TARS2 SARS2 EIF2AK4

3.57e-04181473IPR006195
DomainAA_TRNA_LIGASE_II

TARS2 SARS2 EIF2AK4

3.57e-04181473PS50862
DomainARM-type_fold

DCAF1 IPO8 STAG1 NOC2L ZNFX1 RPTOR CLTC NCAPD2 INTS4 DAAM1

3.59e-0433914710IPR016024
Domain-

TCERG1L TCERG1

3.65e-04414721.10.10.440
DomainTRPV1-4_channel

TRPV2 TRPV3

3.65e-0441472IPR008347
Domain-

UBASH3A PPIP5K1 PPIP5K2

4.94e-042014733.40.50.1240
DomainHis_PPase_superfam

UBASH3A PPIP5K1 PPIP5K2

4.94e-04201473IPR029033
DomainSpectrin

KALRN DST UTRN

7.54e-04231473PF00435
DomainACTININ_2

LCP1 DST UTRN

7.54e-04231473PS00020
DomainACTININ_1

LCP1 DST UTRN

7.54e-04231473PS00019
DomainActinin_actin-bd_CS

LCP1 DST UTRN

7.54e-04231473IPR001589
Domain-

BRIP1 MYO1E ABCC5 DDX56 ZNFX1 FANCM GUF1 NWD2 GNA14 CHST4 GNA12 DNA2 DHX29 HYDIN DYNC1H1

8.11e-04746147153.40.50.300
DomainFF_domain

TCERG1L TCERG1

9.04e-0461472IPR002713
DomainFF

TCERG1L TCERG1

9.04e-0461472PS51676
DomainGphrmn_rcpt_fam

FSHR LGR6

9.04e-0461472IPR002131
DomainFF

TCERG1L TCERG1

9.04e-0461472PF01846
DomainFF

TCERG1L TCERG1

9.04e-0461472SM00441
DomainAcid_Pase_AS

PPIP5K1 PPIP5K2

9.04e-0461472IPR033379
DomainP-loop_NTPase

BRIP1 MYO1E MYO5B ABCC5 DDX56 ZNFX1 FANCM GUF1 NWD2 GNA14 CHST4 GNA12 DNA2 DHX29 HYDIN DYNC1H1

1.06e-0384814716IPR027417
DomainHECT

HECW1 HECTD2 HECW2

1.22e-03271473PF00632
DomainHECTc

HECW1 HECTD2 HECW2

1.22e-03271473SM00119
DomainHECT_dom

HECW1 HECTD2 HECW2

1.22e-03271473IPR000569
DomainHECT

HECW1 HECTD2 HECW2

1.22e-03271473PS50237
DomainHIS_ACID_PHOSPHAT_2

PPIP5K1 PPIP5K2

1.26e-0371472PS00778
DomainHIS_ACID_PHOSPHAT_1

PPIP5K1 PPIP5K2

1.26e-0371472PS00616
DomainARM-like

DCAF1 IPO8 STAG1 DOCK10 RPTOR NCAPD2 INTS4 DAAM1

1.36e-032701478IPR011989
DomainSpectrin_repeat

KALRN DST UTRN

1.50e-03291473IPR002017
DomainHis_Pase_clade-2

PPIP5K1 PPIP5K2

1.67e-0381472IPR000560
DomainHis_Phos_2

PPIP5K1 PPIP5K2

1.67e-0381472PF00328
DomainC2_dom

TPTE HECW1 HECW2 PLCH1 MCTP2 CCDC33

1.91e-031641476IPR000008
DomainSPEC

KALRN DST UTRN

2.00e-03321473SM00150
DomainSpectrin/alpha-actinin

KALRN DST UTRN

2.00e-03321473IPR018159
DomainDNA/RNA_helicase_DEAH_CS

BRIP1 FANCM DHX29

2.60e-03351473IPR002464
Domain-

TARS2 EIF2AK4

3.23e-031114723.40.50.800
DomainDEAH_ATP_HELICASE

BRIP1 FANCM DHX29

3.29e-03381473PS00690
DomainC2

HECW1 HECW2 PLCH1 MCTP2 CCDC33

3.80e-031311475PF00168
DomainC2

HECW1 HECW2 PLCH1 MCTP2 CCDC33

4.59e-031371475SM00239
Domain-

DCAF1 RAE1 FBXW12 SEMA5A DENND3 NWD2 SEMA5B RPTOR

4.92e-0333314782.130.10.10
DomainWD40/YVTN_repeat-like_dom

DCAF1 RAE1 FBXW12 SEMA5A DENND3 NWD2 SEMA5B RPTOR

5.10e-033351478IPR015943
DomainAnticodon-bd

TARS2 EIF2AK4

5.26e-03141472IPR004154
DomainC2

HECW1 HECW2 PLCH1 MCTP2 CCDC33

5.34e-031421475PS50004
Domain-

HECW1 HECW2 PLCH1 MCTP2 CCDC33

6.34e-0314814752.60.40.150
DomainHEAT

RPTOR NCAPD2 INTS4

6.38e-03481473PF02985
DomainGproteinA_insert

GNA14 GNA12

6.87e-03161472IPR011025
Domain-

GNA14 GNA12

6.87e-031614721.10.400.10
DomainG-alpha

GNA14 GNA12

6.87e-03161472PF00503
DomainG_alpha

GNA14 GNA12

6.87e-03161472SM00275
DomainSH3

MYO1E KALRN UBASH3A DST PIK3R1 DNMBP

7.32e-032161476PS50002
DomainGprotein_alpha_su

GNA14 GNA12

7.74e-03171472IPR001019
PathwayKEGG_MEDICUS_REFERENCE_FANCONI_ANEMIA_PATHWAY

FANCM FANCD2 FANCG FANCI

1.87e-05191224M47853
PathwayPID_FANCONI_PATHWAY

BRIP1 FANCM FANCD2 FANCG FANCI

5.13e-05471225M1
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

UBR1 DOCK10 GON4L ZNFX1 TARS2 WLS DENND3 SULF2 DST TCERG1 MLH1 MTR EIF2AK4 PPIP5K2 PLCH1 DNA2 CNOT4

3.28e-096501491738777146
Pubmed

The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.

BRIP1 FANCM FANCD2 FANCG FANCI

3.91e-0915149519536649
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

POP4 RMND5A IPO8 RAE1 PITRM1 MYO1E MYO5B ERO1A TARS2 WLS LGALS1 FANCD2 FANCI GCC2 PRKACA INTS4 DNA2 TGS1

4.55e-097541491833060197
Pubmed

The carboxyl terminus of FANCE recruits FANCD2 to the Fanconi Anemia (FA) E3 ligase complex to promote the FA DNA repair pathway.

FANCM FANCD2 FANCG FANCI

1.12e-087149424451376
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

MYO1E SWAP70 GNE ERO1A TOM1L1 CARS1 PSME2 RRM1 LGALS1 FANCD2 FANCI TLN1 ANP32A NCAPD2 PRKACA SF3A3 MTR IKBKB DNMBP TATDN1 USP15 FKBP4 DYNC1H1 VCPIP1

1.47e-0814551492422863883
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

DCAF1 UBR1 GNE NOC2L DOCK10 DDX56 RRM1 ERBIN LGALS1 CCNT1 GUF1 DST TCERG1 FANCI RPTOR TLN1 CLTC NCAPD2 SF3A3 MLH1 DHX29 UTRN DYNC1H1

1.76e-0813531492329467282
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

DCAF1 DOCK10 GON4L ERBIN ZBED4 GCC2 TLN1 CLTC PPIP5K1 LRRC7 USP15 DYNC1H1 VCPIP1

2.54e-084071491312693553
Pubmed

Fanconi Anemia

BRIP1 FANCM FANCD2 FANCG FANCI

4.27e-0823149520301575
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

IPO8 PITRM1 NOC2L ERO1A CARS1 DDX56 IDH2 TARS2 FANCD2 TCERG1 FANCI RPTOR TLN1 CLTC ANP32A NCAPD2 PRKACA SF3A3 MTR DHX29 FKBP4 DYNC1H1

1.97e-0714251492230948266
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

RMND5A IPO8 MYO1E NOC2L ERO1A DDX56 PSME2 IDH2 RRM1 ERBIN FANCD2 DST FANCI TLN1 STAU2 CLTC ANP32A NCAPD2 SF3A3 IKBKB DHX29 DYNC1H1

2.36e-0714401492230833792
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

DCAF1 TLK2 TRAF6 RMND5A IPO8 PITRM1 MYO1E MYO5B STYXL2 IDH2 CCNYL1 DCP1B PIK3R1 GCC2 RPTOR PRKACA SF3A3 PXMP2 PPIP5K2 USP15 DYNC1H1

2.39e-0713211492127173435
Pubmed

FANCJ protein is important for the stability of FANCD2/FANCI proteins and protects them from proteasome and caspase-3 dependent degradation.

BRIP1 FANCD2 FANCI

3.07e-074149326336824
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

ERBIN FANCD2 CCNT1 TCERG1 RPTOR TLN1 SLITRK5 DHX29 UTRN

4.12e-07215149935973513
Pubmed

Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2.

FANCD2 FANCG FANCI MLH1

4.26e-0715149420603015
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

TLK2 UBR1 TRAF6 TOM1L1 IRF5 RPTOR STAU2 DAAM1 IKBKB FKBP4

4.39e-072831491021903422
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

TBC1D19 DCAF1 POP4 SWAP70 ERO1A DST TLN1 MLH1 PPIP5K2 UTRN DYNC1H1

4.85e-073601491133111431
Pubmed

Esophageal Atresia / Tracheoesophageal Fistula Overview – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

BRIP1 FANCM FANCD2 FANCG

5.66e-0716149420301753
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

HECW1 DOCK10 ERBIN SULF2 DST ALMS1 TLN1 PHLPP1 USP15

6.02e-07225149912168954
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

SWAP70 CARS1 PSME2 RRM1 LCP1 TCERG1 TLN1 CLTC NCAPD2 SF3A3 ADAMTS20 LRRC7 DHX29 UTRN FKBP4 DYNC1H1

8.01e-078471491635235311
Pubmed

Crosstalk between BRCA-Fanconi anemia and mismatch repair pathways prevents MSH2-dependent aberrant DNA damage responses.

BRIP1 FANCD2 MLH1

1.53e-066149324966277
Pubmed

FANCI is a negative regulator of Akt activation.

FANCD2 FANCI PHLPP1

1.53e-066149327097374
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

SMAP1 RAE1 HECW1 KALRN ZNFX1 IDH2 ERBIN GRK2 RPTOR STAU2 CLTC ANP32A SLITRK5 LRRC7 DAAM1 USP15 DHX29 VCPIP1

2.03e-0611391491836417873
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

IPO8 RAE1 NOC2L DOCK10 CCNT1 TCERG1 FANCI PIK3R1 TLN1 ANP32A PRKACA PPIP5K2 DNMBP USP15 UTRN FKBP4

2.20e-069161491632203420
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

ABCC5 RRM1 ERBIN DST TCERG1 FANCI TLN1 NCAPD2 SLITRK5 LRRC7 PLCH1 DHX29 DYNC1H1 VCPIP1

2.40e-067081491439231216
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

TRAF6 STAG1 MYO1E KALRN ABCC5 ZNFX1 UBASH3A GUF1 SARS2 DST TCERG1 HECTD2 PIK3R1 CLTC CCDC15 UTRN GEN1 DYNC1H1 VCPIP1

2.72e-0612851491935914814
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PITRM1 SULF2 DST SEMA5B HECW2 RPTOR NCAPD2 EIF2AK4 DAAM1 PPIP5K2 DNA2 DNMBP

3.26e-065291491214621295
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SMAP1 MYO1E MYO5B KALRN ZNFX1 IDH2 ERBIN NWD2 DST GRK2 HECW2 RPTOR TLN1 CLTC PRKACA LRRC7 PLCH1 DHX29 UTRN DYNC1H1

3.40e-0614311492037142655
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

ERBIN DST ALMS1 DCP1B MYPN STAU2 UTRN VCPIP1

3.59e-06209149836779422
Pubmed

A protein interaction landscape of breast cancer.

DCAF1 BRIP1 RAE1 MYO5B CARS1 ERBIN DST FANCI PIK3R1 TLN1 CLTC MLH1 FKBP4

3.78e-066341491334591612
Pubmed

DNA polymerase POLN participates in cross-link repair and homologous recombination.

FANCD2 FANCG FANCI

4.25e-068149319995904
Pubmed

FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.

FANCD2 FANCI MLH1

4.25e-068149334469738
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

SWAP70 ERBIN TLN1 MYPN DNMBP USP15 DHX29 VCPIP1

4.57e-06216149831519766
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DCAF1 IPO8 NOC2L ERO1A TARS2 RRM1 ERBIN GUF1 SARS2 PIK3R1 TLN1 STAU2 CLTC PRKACA MTR DAAM1 PLCH1 DNA2 DHX29 FKBP4

6.01e-0614871492033957083
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

DCAF1 MYO1E FANCD2 CCNT1 FANCI HECW2 SF3A3 MTR UTRN

8.95e-06313149938270169
Pubmed

An endothelin-1 switch specifies maxillomandibular identity.

GSC DLX2 DLX5

9.05e-0610149319017795
Pubmed

Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk.

BRIP1 FANCM FANCD2 FANCG

9.30e-0631149419690177
Pubmed

Defining the membrane proteome of NK cells.

ERO1A DOCK10 DDX56 PSME2 GRK2 DCP1B FANCI PIK3R1 GCC2 STAU2 CLTC NCAPD2 PXMP2 MLH1 DAAM1 MCTP2 DYNC1H1

1.16e-0511681491719946888
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

KALRN DCP1B FANCI GCC2 RPTOR MYPN STAU2 NCAPD2 USP15 DHX29 FKBP4

1.19e-055031491116964243
Pubmed

Spatio-temporal dynamics of gene expression of the Edn1-Dlx5/6 pathway during development of the lower jaw.

GSC DLX2 DLX5

1.24e-0511149320333701
Pubmed

Forkhead transcription factor FoxF1 interacts with Fanconi anemia protein complexes to promote DNA damage response.

FANCM FANCD2 FANCI

1.24e-0511149326625197
Pubmed

Ectodermal-derived Endothelin1 is required for patterning the distal and intermediate domains of the mouse mandibular arch.

GSC DLX2 DLX5

1.24e-0511149322902530
Pubmed

The spontaneous mouse mutant low set ears (Lse) is caused by tandem duplication of Fgf3 and Fgf4.

GSC DLX2 DLX5

1.24e-0511149337341808
Pubmed

The Fanconi anemia pathway promotes replication-dependent DNA interstrand cross-link repair.

FANCD2 FANCG FANCI

1.24e-0511149319965384
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

SWAP70 TLN1 MYPN CLTC PHLPP1 USP15 DYNC1H1 VCPIP1

1.57e-05256149833397691
Pubmed

A human ortholog of archaeal DNA repair protein Hef is defective in Fanconi anemia complementation group M.

FANCM FANCD2 FANCG

1.65e-0512149316116422
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RAE1 KALRN DDX56 IDH2 NWD2 SULF2 DST ZBED4 TCERG1 STAU2 CLTC SF3A3 INTS4 GNA12 PPIP5K2 DYNC1H1

1.76e-0510821491638697112
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

BRIP1 ERO1A WLS ERBIN ALMS1 DCP1B SF3A3 MTR PPIP5K2 PLCH1 USP15 VCPIP1 TGS1

1.76e-057331491334672954
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

RAE1 STAG1 NOC2L DDX56 ERBIN CCNT1 FANCI NCAPD2 PRKACG

1.77e-05341149932971831
Pubmed

Polymorphisms of the TRPV2 and TRPV3 genes associated with fibromyalgia in a Korean population.

TRPV2 TRPV3

1.82e-052149227079220
Pubmed

Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.

PPIP5K1 PPIP5K2

1.82e-052149218981179
Pubmed

DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex.

FANCD2 FANCI

1.82e-052149232269332
Pubmed

FANCI functions as a repair/apoptosis switch in response to DNA crosslinks.

FANCD2 FANCI

1.82e-052149234256011
Pubmed

FANCI protein binds to DNA and interacts with FANCD2 to recognize branched structures.

FANCD2 FANCI

1.82e-052149219561358
Pubmed

Ubiquitination-Linked Phosphorylation of the FANCI S/TQ Cluster Contributes to Activation of the Fanconi Anemia I/D2 Complex.

FANCD2 FANCI

1.82e-052149228636932
Pubmed

FANCJ suppresses microsatellite instability and lymphomagenesis independent of the Fanconi anemia pathway.

BRIP1 FANCD2

1.82e-052149226637282
Pubmed

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis.

FANCD2 FANCI

1.82e-052149219465922
Pubmed

Expression and purification of human FANCI and FANCD2 using Escherichia coli cells.

FANCD2 FANCI

1.82e-052149225168188
Pubmed

Protein kinase A phosphorylates and regulates the osteogenic activity of Dlx5.

PRKACA DLX5

1.82e-052149221406180
Pubmed

IKKβ is an IRF5 kinase that instigates inflammation.

IRF5 IKBKB

1.82e-052149225326420
Pubmed

Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal.

FANCD2 FANCI

1.82e-052149224278431
Pubmed

FANCD2-FANCI surveys DNA and recognizes double- to single-stranded junctions.

FANCD2 FANCI

1.82e-052149239085614
Pubmed

Phosphorylation-dependent association of the G4-1/G5PR regulatory subunit with IKKβ negatively modulates NF-κB activation through recruitment of protein phosphatase 5.

IKBKB PPP2R3C

1.82e-052149220925653
Pubmed

The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.

PPIP5K1 PPIP5K2

1.82e-052149228126903
Pubmed

Structural insight into FANCI-FANCD2 monoubiquitination.

FANCD2 FANCI

1.82e-052149232725171
Pubmed

Mechanism, specificity, and function of FANCD2-FANCI ubiquitination and deubiquitination.

FANCD2 FANCI

1.82e-052149234137174
Pubmed

Dystonin deficiency reduces taste buds and fungiform papillae in the anterior part of the tongue.

SULF2 DST

1.82e-052149217156752
Pubmed

Homocysteine inhibits neural stem cells survival by inducing DNA interstrand cross-links via oxidative stress.

FANCD2 FANCI

1.82e-052149227773793
Pubmed

FANCI Regulates Recruitment of the FA Core Complex at Sites of DNA Damage Independently of FANCD2.

FANCD2 FANCI

1.82e-052149226430909
Pubmed

FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses.

BRIP1 FANCD2

1.82e-052149220676667
Pubmed

Immune complex-induced integrin activation and L-plastin phosphorylation require protein kinase A.

LCP1 PRKACA

1.82e-052149210446213
Pubmed

Temporospatial cell interactions regulating mandibular and maxillary arch patterning.

DLX2 DLX5

1.82e-052149210603356
Pubmed

Impaired FANCD2 monoubiquitination and hypersensitivity to camptothecin uniquely characterize Fanconi anemia complementation group M.

FANCM FANCD2

1.82e-052149219423727
Pubmed

Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays.

FANCD2 FANCI

1.82e-052149232167469
Pubmed

Novel insights into the TRPV3-mediated itch in atopic dermatitis.

TRPV3 GRHL3

1.82e-052149233035568
Pubmed

Characterization of the cAMP-dependent protein kinase catalytic subunit Cgamma expressed and purified from sf9 cells.

PRKACA PRKACG

1.82e-052149215039079
Pubmed

FANCI and FANCD2 have common as well as independent functions during the cellular replication stress response.

FANCD2 FANCI

1.82e-052149229059323
Pubmed

TRAF6 mediates human DNA2 polyubiquitination and nuclear localization to maintain nuclear genome integrity.

TRAF6 DNA2

1.82e-052149231216032
Pubmed

Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.

PPIP5K1 PPIP5K2

1.82e-052149217702752
Pubmed

FANCI is a second monoubiquitinated member of the Fanconi anemia pathway.

FANCD2 FANCI

1.82e-052149217460694
Pubmed

The Fanconi anemia proteins FANCD2 and FANCJ interact and regulate each other's chromatin localization.

BRIP1 FANCD2

1.82e-052149225070891
Pubmed

The FANCD2-FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2.

FANCD2 FANCI

1.82e-052149227405460
Pubmed

Structure of the FANCI-FANCD2 complex: insights into the Fanconi anemia DNA repair pathway.

FANCD2 FANCI

1.82e-052149221764741
Pubmed

Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.

PPIP5K1 PPIP5K2

1.82e-052149217690096
Pubmed

Regulation of membrane targeting of the G protein-coupled receptor kinase 2 by protein kinase A and its anchoring protein AKAP79.

GRK2 PRKACA

1.82e-052149211278469
Pubmed

Cytokinesis failure occurs in Fanconi anemia pathway-deficient murine and human bone marrow hematopoietic cells.

FANCD2 FANCG

1.82e-052149220921626
Pubmed

Mechanism of Ubiquitination and Deubiquitination in the Fanconi Anemia Pathway.

FANCD2 FANCG FANCI

2.14e-0513149327986371
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

MYO1E KALRN DDX56 IRF5 SARS2 DST ZBED4 FANCI RPTOR TLN1 NCAPD2 GNA12 DLX2 DNMBP PPP2R3C DYNC1H1

2.28e-0511051491635748872
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

IPO8 PITRM1 DDX56 IDH2 TARS2 FANCD2 GUF1 SARS2 DST ALMS1 PIK3R1 RPTOR STAU2 CLTC PRKACA MTR GEN1 FKBP4 VCPIP1

2.32e-0514961491932877691
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

POP4 NOC2L GON4L DDX56 ERBIN CCNT1 GUF1 DST TCERG1 TLN1 STAU2 NCAPD2 PRKACA MLH1 DAAM1 DNMBP SGF29 DHX29 UTRN

2.34e-0514971491931527615
Pubmed

NEDL2 regulates enteric nervous system and kidney development in its Nedd8 ligase activity-dependent manner.

HECW1 PIK3R1 HECW2

2.71e-0514149327119228
Pubmed

Cre-mediated gene inactivation demonstrates that FGF8 is required for cell survival and patterning of the first branchial arch.

GSC DLX2 DLX5

2.71e-0514149310601039
Pubmed

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.

PITRM1 IDH2 LGALS1 TCERG1 STAU2 DHX29 DYNC1H1

2.90e-05203149735012549
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

DCAF1 POP4 RAE1 FANCD2 ALMS1 DCP1B STAU2 DNA2 TGS1

2.94e-05364149924778252
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

RAE1 PSME2 FANCD2 FANCI RPTOR NCAPD2 PRKACA MTR USP15 DYNC1H1 VCPIP1

3.81e-055711491137167062
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

UBR1 RMND5A GNE DST FANCI HECW2 GCC2

3.82e-05212149733853758
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

TLK2 SMAP1 TRAF6 NOC2L DDX56 LGALS1 SARS2 FANCI PIK3R1 CLTC PRKACA SF3A3 MTR LRRC7 USP15 FKBP4 DYNC1H1

3.85e-0512841491717353931
Pubmed

Elucidation of the Fanconi Anemia Protein Network in Meiosis and Its Function in the Regulation of Histone Modifications.

FANCM FANCD2 MLH1

4.14e-0516149327760317
Pubmed

Foxi transcription factors promote pharyngeal arch development by regulating formation of FGF signaling centers.

GSC DLX2 DLX5

4.14e-0516149324650709
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

DCAF1 PITRM1 IDH2 TARS2 RRM1 ERBIN GUF1 SARS2 PIK3R1 RPTOR ALDH3A1 DYNC1H1

4.28e-056861491228380382
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TPTE MYO5B TARS2 ERBIN FANCD2 FANCI PIK3R1 CLTC PRKACA MLH1 PHLPP1 INTS4 EIF2AK4 UTRN FKBP4

4.79e-0510491491527880917
GeneFamilyRing finger proteins|Fanconi anemia complementation groups|Protein phosphatase 1 regulatory subunits|BRCA1 A complex|BRCA1 B complex|BRCA1 C complex

BRIP1 FANCM FANCD2 FANCG FANCI

5.25e-0820955548
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

HECW1 HECW2 CCDC33

8.85e-0436953823
GeneFamilyUPF1 like RNA helicases

ZNFX1 DNA2

1.46e-03119521169
GeneFamilySmall leucine rich repeat proteoglycans

KERA PRELP

1.74e-0312952573
CoexpressionMATHEW_FANCONI_ANEMIA_GENES

BRIP1 FANCM FANCD2 FANCG

3.12e-07111484M12972
CoexpressionGSE3982_DC_VS_NEUTROPHIL_UP

NOC2L RRM1 DST ZBED4 CLTC TRPV2 PXMP2 GNA12 CNOT4

2.15e-062001489M5461
CoexpressionGSE39820_TGFBETA1_VS_TGFBETA3_IN_IL6_IL23A_TREATED_CD4_TCELL_UP

TPTE IPO8 KALRN NOC2L WLS GRK2 MTR ADAMTS20

1.89e-052001488M5627
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

TLK2 SMAP1 CCNYL1 ALMS1 SLC16A4 TCERG1 HECTD2 GCC2 CCDC15 USP15 GEN1 TGS1

1.95e-0631114812Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasB cells, B.GC.Sp, CD19+ IgM+ IgD- GL7+ PNA+, Spleen, avg-3

BRIP1 MYO1E SWAP70 IRF5 RRM1 FANCM DENND3 FANCD2 FANCI STAU2 NCAPD2 DNA2 GEN1

2.72e-0638014813GSM538207_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

TLK2 SMAP1 MYO5B CCNYL1 ALMS1 SLC16A4 TCERG1 DCP1B SEMA5B HECTD2 GCC2 SLITRK5 CCDC15 PHLPP1 DAAM1 IKBKB PLCH1 USP15 GEN1 TGS1

1.81e-0598914820Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e8.5_Floor Plate_top-relative-expression-ranked_2500_k-means-cluster#1

TLK2 POP4 FANCM CCNT1 CCNYL1 DST ALMS1 SLC16A4 TCERG1 ANP32A USP15 GEN1 TGS1

2.57e-0546914813Facebase_RNAseq_e8.5_Floor Plate_2500_K1
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

DCAF1 TLK2 SMAP1 IPO8 CA14 GLB1L2 FANCM TTC6 FANCD2 CFAP54 ALMS1 ZBED4 SEMA5B HECTD2 GCC2 ANP32A CCDC15 PHLPP1 SNX31 DLX5 PLCH1 DNA2 GEN1 TGS1

4.37e-05141414824facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

DCAF1 TLK2 SMAP1 POP4 PITRM1 SEMA5A FANCM CFAP54 SULF2 CCNYL1 ALMS1 ZBED4 HECTD2 GCC2 STAU2 ANP32A MLH1 PPIP5K2 DNA2 GEN1 CNOT4 TGS1

5.68e-05125214822facebase_RNAseq_e10.5_MaxArch_2500_K3
ToppCellControl-Control-Lymphocyte-T/NK-T/NK_proliferative|Control / Disease, condition lineage and cell class

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2 DNA2

3.86e-0720014986cf63dd57f6bc0c42e7182322dd24ff9afbe9186
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DPP10 HECW1 NWD2 MYPN LRRC7 LGR6 HYDIN

1.26e-061621497bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 RRM1 FANCD2 FANCG FANCI CCDC15 DNA2

1.42e-06165149788681101d7cf60b99b8ace5d8c0944323b937306
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

BRIP1 IDH2 FANCG FANCI NCAPD2 SLITRK5 DNA2

1.88e-0617214976fcc16f1067672967ecbcdfdc727649ae9891dd9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCERG1L MYO1E CXorf65 LGALS1 MYPN GRHL3

2.90e-0611814963f0a304ef9c9e5ba047fc09f4372590eed624328
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRIP1 SEMA5A RRM1 FANCD2 FANCI LRRC7 DNA2

3.63e-061901497e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BRIP1 FANCD2 SLC16A4 FANCI NCAPD2 DNA2 GEN1

3.63e-061901497d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

BRIP1 FANCM FANCD2 FANCI NCAPD2 DNA2 GEN1

4.02e-0619314974b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Stem_cells-neuroepithelial-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

GNE SULF2 RPTOR DLX2 DLX5 GEN1

4.43e-0612714969071cd0953c8bb6746dc9cd13d153e3d6ef40b08
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 CCDC15 DNA2

4.45e-0619614971d2e0b328eb822db7521b5f5724d4bd17c0bad5f
ToppCell390C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

BRIP1 IDH2 RRM1 FANCI NCAPD2 MTR DNA2

4.45e-06196149736ed1918f70b6f5760bb088b15ce422998055cc7
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 CCDC15 DNA2

4.60e-06197149784ed777cdba569200a3ef1654d8a12f17fcfb7f1
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

SEMA5A WLS ERBIN LGALS1 DST DLX2 DLX5

4.60e-06197149758b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 CCDC15 DNA2

4.60e-0619714978b616cde333bdbc0c591035ad9e4949155866245
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

PSME2 LCP1 GRK2 TLN1 USP15 UTRN DYNC1H1

4.76e-06198149761ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

4.92e-061991497e98ff036d04fc78dffef156bdc0d644532274067
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

4.92e-061991497305a9ade5bbe8e981e7c641c9a5e0c9f8ef60470
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

4.92e-0619914977feedb0bf84a3361c8ab5b6674ff64e8ff140c23
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

4.92e-061991497123fbf2122aa221d8cbf3aef9361ba0982c07695
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

4.92e-061991497fba48342066aab41a8bcb20db40a6df0158e1cbe
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

4.92e-0619914976b1304417cf9c44ca70d2bfc2b5acc1a206f25b6
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Mild / Disease, condition lineage and cell class

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

5.08e-0620014976126a3bbafe2110fba0c1c4493035df4e8193d22
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Severe / Disease, condition lineage and cell class

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 PXMP2

5.08e-0620014970892603e604c2a945dd720685d45970f855bd5d3
ToppCellBiopsy_Control_(H.)-Immune-Proliferating_Macrophages|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

BRIP1 RRM1 FANCG FANCI NCAPD2 DNA2 GEN1

5.08e-062001497ce9fad55f779afd3d6c5a9c5a15e2d9f548b7c7e
ToppCellBL-critical-LOC-Lymphoid-Treg|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2 DNA2

5.08e-06200149704d95a9102248e98eed069840ea6d3d23a243fd5
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TCERG1L SEMA5A GLB1L2 SEMA5B DLX2 DLX5

9.12e-0614414960322fef818a963be00535d5f141f028d43de5c6a
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP10 HECW1 NWD2 MYPN LRRC7 HYDIN

9.49e-06145149696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RNF144B MYO1E LGALS1 MYPN DLX5 PLCH1

2.19e-0516814962572a3dd4f3f619bd26a3cd6e60de43821d8bb64
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RRM1 ALMS1 CLTC PPIP5K1 EIF2AK4 VCPIP1

2.19e-05168149608f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellCV-Mild-7|CV / Virus stimulation, Condition and Cluster

TLK2 TRAF6 GLB1L2 FANCD2 FANCI INTS4

2.34e-05170149625ebde7d2f8ae1afdfaf5876284ff20bb179eb10
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 IRF5 LGALS1 SULF2 IKBKB DNA2

2.34e-051701496a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 IRF5 LGALS1 SULF2 IKBKB DNA2

2.34e-051701496ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RMND5A GNE MYO5B DENND3 HECTD2 MCTP2

2.42e-051711496d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCellfacs-Lung-EPCAM-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 IRF5 LCP1 GRK2 TRPV2 DNA2

2.58e-05173149650b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA14 IDH2 IGFALS MYPN SLITRK5 PXMP2

2.94e-051771496692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CA14 IDH2 IGFALS MYPN SLITRK5 PXMP2

2.94e-051771496c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

KALRN SEMA5A DENND3 SEMA5B SNX31 UTRN

3.54e-051831496e3835db4795362b0442d5893baf2a78efcc20428
ToppCellCOVID-19_Mild-gd_T|COVID-19_Mild / Disease condition and Cell class

LCP1 GSC ERBIN PIK3R1 TLN1 UTRN

3.54e-051831496f593a89b0aa8fffdfa403769916facfd30358521
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GSC GNA14 SEMA5B FANCI HECW2 UTRN

3.65e-051841496688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK10 ABCC5 LCP1 SULF2 DST DLX5

3.65e-051841496fe9ea4d0e0be820e95eaf9bb42a5560d0e177574
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

KALRN SEMA5A DENND3 SEMA5B SNX31 UTRN

3.76e-051851496ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRIP1 FANCD2 FANCI NCAPD2 PLCH1 GEN1

3.87e-0518614969feef5936985e936b3d88f9d1bb012abb6468570
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BRIP1 RRM1 CCDC15 DLX2 DLX5 DNA2

3.87e-0518614964fe8e0bf74c7dbf73634cafdacad89020d2634d0
ToppCellCV-Moderate-7|CV / Virus stimulation, Condition and Cluster

BRIP1 DOCK10 CCNT1 CLTC DNA2 MCTP2

3.87e-0518614968571956890fc9894d766ba294a28e376b4aba428
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DOCK10 ABCC5 LCP1 SULF2 DST DLX5

3.87e-0518614967950e03ea080238c168b9d807e217f459acdfb28
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BRIP1 FANCD2 FANCI NCAPD2 PLCH1 GEN1

3.87e-05186149689f5b06bc56674af304912d481ac697c7c870904
ToppCelldroplet-Marrow-BM-1m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 IRF5 IDH2 LGALS1 SULF2 TRPV2

3.99e-051871496028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

RNF144B MYO1E SWAP70 CFAP54 SULF2 UTRN

3.99e-05187149640ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BRIP1 FANCD2 FANCI NCAPD2 DNA2 GEN1

3.99e-0518714969351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellwk_15-18-Hematologic-Myeloid-Basophil|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AMPD3 ERO1A GRK2 TRPV2 STX11 USP15

4.11e-0518814963638d85452de15a060146628fbbad9d2a36feb13
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RNF144B GNE CFAP54 MCTP2 UTRN HYDIN

4.11e-05188149663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellMS-CD8-CD4_Treg|MS / Condition, Cell_class and T cell subcluster

TBC1D19 STAG1 CCNYL1 PIK3R1 INTS4 MCTP2

4.11e-0518814962f0e2c7d79ee2d69a5d908c0247dc950c056c30a
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK10 ABCC5 LCP1 SULF2 DST CLTC

4.23e-051891496b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RNF144B DPP10 UTS2B MYO5B WLS PPIP5K2

4.23e-05189149699a13b1b669b0cd36e3096632351d9ade25d1173
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BRIP1 FANCD2 FANCI NCAPD2 CCDC15 GEN1

4.23e-0518914961e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOCK10 LCP1 PIK3R1 LGR6 MCTP2 UTRN

4.36e-051901496d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCelldroplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK10 ABCC5 LCP1 SULF2 DST CLTC

4.36e-051901496da58227565ad6a690828dd8554dd3670222f8582
ToppCellMild-T/NK_proliferative|World / Disease group and Cell class

RRM1 FANCD2 FANCG FANCI NCAPD2 GEN1

4.49e-0519114969dba5526fd5ea8065ad305feb2ee562335f887c6
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ERBIN DST PIK3R1 CLTC ANP32A

4.76e-05193149606b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ERBIN DST PIK3R1 CLTC ANP32A

4.76e-0519314969c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP10 LGALS1 SULF2 PRELP PIK3R1 DAAM1

4.76e-05193149696c85b250d04b5f400512097d925061c6dc2906b
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ERBIN DST PIK3R1 CLTC ANP32A

4.76e-051931496a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRIP1 HECW1 RRM1 FANCD2 FANCI DNA2

4.76e-051931496bbdfda6665941cfa1965418bb91ef9ff43b1326f
ToppCellControl-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

RNF144B DENND3 SULF2 DNMBP MCTP2 UTRN

4.76e-0519314963479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-Cycling_T|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

4.76e-05193149681e6240cffb094b2aa3684fd0889b6497f47c4f0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRIP1 HECW1 RRM1 FANCD2 FANCI DNA2

4.76e-051931496516ea2c12bdc7a5dc676159d627e36f6abe13ef0
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK10 ERBIN DST PIK3R1 CLTC ANP32A

4.76e-051931496b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Sema3e_Kank4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RNF144B MYO1E LGALS1 MYPN GRHL3

4.82e-051181495d7dcffc0476a6e471debd83904a6569c6f27a594
ToppCell3'_v3-Lung-Myeloid_Mac-Cycling_Myeloid-Mac|Lung / Manually curated celltypes from each tissue

BRIP1 IDH2 RRM1 FANCD2 FANCI NCAPD2

4.90e-051941496a8ae49157ca3f9e8b3f1750a995aee012dc859b6
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

4.90e-051941496f9070035553bc68106a9e0bdf4b507715a138aba
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TBC1D19 KALRN DOCK10 DST HECTD2 DLX5

4.90e-051941496b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

BRIP1 GNE FAM227B RRM1 FANCD2 PXMP2

4.90e-0519414968f4b63b0b9a40765205e4ca6bd94a675a83dbe3d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RNF144B MYO5B DOCK10 WLS DLX2 DLX5

4.90e-05194149602a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI CCDC15 DNA2

5.04e-051951496cec7df321f372d05c94f97d6bb18891a5cc3dec3
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI CCDC15 DNA2

5.04e-051951496b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

5.04e-051951496764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

5.04e-051951496926eb3fc5d028be936885bea0654a77db3107234
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

BRIP1 RRM1 FANCI PXMP2 DNA2 HYDIN

5.04e-051951496957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

5.04e-0519514961a5e814e12fe37287dbfc58189e1958e2c76b5da
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI CCDC15 DNA2

5.04e-05195149656d8734d020b3da08a5aa9e67999706a9e023a99
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

ERO1A LCP1 ERBIN GRK2 TLN1 MCTP2

5.18e-05196149615397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI CCDC15 DNA2

5.18e-051961496df366d76ea55f49e349d622effa57c1535df8400
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating3_(7)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

5.18e-0519614961964c5003a0cb84539850a7cfe3bbb0e23a61d2d
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_cycling|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

BRIP1 RRM1 FANCD2 FANCI NCAPD2 DNA2

5.18e-05196149673f951f7712e0aa3323676b9a4b7944d21d347c4
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

ERO1A LCP1 ERBIN GRK2 TLN1 MCTP2

5.18e-051961496f245e929a286cb097130572e1027b4f01be8b04d
ToppCellwk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

KERA SEMA5A LGALS1 SULF2 SEMA5B PRELP

5.18e-051961496eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

MYO5B TTC6 CFAP54 GNA14 PLCH1 HYDIN

5.18e-05196149687d9881cfec461a5d89b688a83749b618c519485
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IDH2 RRM1 FANCG SARS2 NCAPD2 PXMP2

5.18e-051961496de70cc301a8cbaedb0a5ea4a6442dcdaa477822d
ToppCellmLN-B_cell-B_cell_cycling|mLN / Region, Cell class and subclass

RNF144B MYO1E IRF5 PXMP2 DNA2 FKBP4

5.33e-051971496806dddcca85c82bd642008d930c8db16b613d88e
ToppCellBronchial_Biopsy-Epithelial-Basal_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

SEMA5A LGALS1 DST PIK3R1 SNX31 LGR6

5.33e-051971496a4855c5aebea4f0fed4eb035844572e82e5bac46
ToppCellBronchial_Biopsy-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

SEMA5A LGALS1 DST PIK3R1 SNX31 LGR6

5.33e-05197149661c1c29a62d4c033999b7f0183c1e9cdd6a62925
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SEMA5A TTC6 SULF2 SNX31 LGR6 ALDH3A1

5.33e-0519714961e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellmLN-(2)_B_cell-(24)_B_cell_cycling|mLN / shred on region, Cell_type, and subtype

RNF144B MYO1E IRF5 PXMP2 DNA2 FKBP4

5.33e-05197149670fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PSME2 LCP1 LGALS1 TG TLN1 MCTP2

5.33e-051971496b6689a3e01e4c285fc2cb33f8c437078722a3892
ToppCellHealthy_donor-T/NK_proliferative|Healthy_donor / disease group, cell group and cell class (v2)

BRIP1 RRM1 FANCG FANCI PXMP2 DNA2

5.33e-051971496b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.

SEMA5A ERBIN LGALS1 DST DLX2 DLX5

5.48e-051981496a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCellCOVID-19_Moderate-T/NK_proliferative|COVID-19_Moderate / disease group, cell group and cell class

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2

5.48e-051981496166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCellCOVID-19_Moderate-T/NK_proliferative|World / disease group, cell group and cell class

BRIP1 RRM1 FANCD2 FANCG FANCI NCAPD2

5.48e-051981496bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

ZNFX1 PSME2 IDH2 IFIT2 LGALS1 USP15

5.48e-051981496ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RRM1 FANCG FANCI NCAPD2 PXMP2 CCDC15

5.48e-051981496281fc2536cdc4c717b30de156e563c0e4baba99d
ComputationalNeighborhood of MSH2

RRM1 TCERG1 FANCI MLH1

8.07e-0528904GNF2_MSH2
Drugprocarbazine

BRIP1 FANCM TG FANCD2 FANCG FANCI MLH1

2.53e-06931487CID000004915
Drugdiepoxybutane

BRIP1 FANCM LGALS1 FANCD2 FANCG FANCI FKBP4

9.24e-061131487CID000011254
DrugAC1NDP1U

BRIP1 STAG1 RRM1 FANCM FANCD2 FANCG FANCI

1.04e-051151487CID004629339
Drugtyrphostin 23

GRK2 FSHR CLTC PRKACA PRKACG IKBKB FKBP4

1.10e-051161487CID000002052
DrugAC1L1IM7

BRIP1 FANCM FANCD2 FANCG FANCI

1.20e-05461485CID000004638
DrugNSC-364372

BRIP1 IPO8 HECW1 LCP1 FANCM CCNT1 GUF1 TCERG1 FANCI CLTC ANP32A IKBKB USP15

1.74e-0548414813CID000435143
Drugtriethylamine

IGFALS GRK2 PRKACA PRKACG DYNC1H1

1.82e-05501485CID000008471
DrugH 85

TG GRK2 PRKACA PRKACG

2.29e-05261484CID006439306
DiseaseBone marrow hypocellularity

BRIP1 FANCM FANCD2 FANCG FANCI

2.18e-08181455C1855710
DiseaseFanconi Anemia

BRIP1 FANCM FANCD2 FANCG FANCI

1.31e-07251455C0015625
DiseasePancytopenia

BRIP1 FANCM FANCD2 FANCG FANCI

1.62e-07261455C0030312
DiseaseAcute monocytic leukemia

BRIP1 FANCM FANCD2 FANCG FANCI

1.62e-07261455C0023465
DiseaseMiller Dieker syndrome

BRIP1 FANCM FANCD2 FANCG FANCI

2.89e-07291455C0265219
DiseaseFanconi anemia

BRIP1 FANCD2 FANCG FANCI

5.39e-07141454cv:C0015625
DiseaseAbnormality of radial ray

BRIP1 FANCM FANCD2 FANCG FANCI

5.68e-07331455C4228778
DiseaseMalignant Head and Neck Neoplasm

BRIP1 FANCM FANCD2 FANCG FANCI

2.49e-06441455C0278996
DiseaseFanconi anemia (implicated_via_orthology)

BRIP1 FANCM FANCD2

6.39e-0681453DOID:13636 (implicated_via_orthology)
DiseaseFanconi anemia (is_implicated_in)

FANCD2 FANCG FANCI

1.36e-05101453DOID:13636 (is_implicated_in)
DiseaseMYELODYSPLASTIC SYNDROME

BRIP1 FANCM FANCD2 FANCG FANCI

2.02e-05671455C3463824
DiseaseLeukemia, Myelocytic, Acute

BRIP1 IDH2 FANCM FANCD2 FANCG FANCI

2.21e-041731456C0023467
Diseasecortical surface area measurement

STAG1 DOCK10 SEMA5A WLS DENND3 TG SULF2 PIK3R1 STAU2 FSHR MLH1 ADAMTS20 GNA12 DAAM1 MCTP2 CNOT4 CCDC33

3.40e-04134514517EFO_0010736
DiseaseInflammatory Myofibroblastic Tumor

CARS1 CLTC

3.55e-0461452C0334121
Diseaseplatelet component distribution width

SWAP70 KALRN DOCK10 ABCC5 LCP1 GCC2 TLN1 MLH1 GNA12 EIF2AK4 USP15 TGS1

3.67e-0475514512EFO_0007984
Diseaseresponse to interferon-beta

DENND3 GRHL3

4.96e-0471452GO_0035456
Diseaselanguage measurement

TRAF6 DOCK10 GON4L RRM1 CFAP54

5.37e-041341455EFO_0007797
Diseasecerebrospinal fluid clusterin measurement

IDH2 DST SNX31

6.78e-04351453EFO_0007657
Diseasetongue squamous cell carcinoma (is_marker_for)

FANCM FANCG FANCI

7.99e-04371453DOID:0050865 (is_marker_for)
Diseasecortical thickness

WLS DENND3 TG SULF2 PIK3R1 STAU2 FSHR ADAMTS20 SNX31 GNA12 DLX5 PLCH1 SGF29 USP15

1.21e-03111314514EFO_0004840
Diseasecandidiasis (implicated_via_orthology)

SMAP1 ANP32A FUT3

1.33e-03441453DOID:1508 (implicated_via_orthology)
Diseasecarbohydrate measurement

TTC6 EIF2AK4 FUT3

1.51e-03461453EFO_0004998
Diseaseserum gamma-glutamyl transferase measurement

UBR1 BRIP1 STAG1 KALRN GON4L FAM227B PIK3R1 TLN1 MLH1 FUT3 DNMBP CNOT4

1.91e-0391414512EFO_0004532
DiseaseTobacco Dependence

LCP1 RPTOR

2.10e-03141452C0040332
DiseaseNicotine Dependence

LCP1 RPTOR

2.10e-03141452C0028043
DiseaseNicotine Use Disorder

LCP1 RPTOR

2.10e-03141452C0376384
DiseaseS-7-hydroxywarfarin measurement

PIK3R1 CHST4 MYPN DNA2

2.16e-031101454EFO_0803329
Diseaseleft ventricular diastolic function measurement

MYO1E DENND3 PIK3R1

2.40e-03541453EFO_0008204
Diseasecancer biomarker measurement

PPIP5K1 FUT3

2.41e-03151452EFO_0005127
Diseaseleukemia

BRIP1 FANCD2 FANCG

2.53e-03551453C0023418
Diseaseantihyperlipidemic drug use measurement

STAG1 DDX56 LCP1 TRMU

2.54e-031151454EFO_0803367
Diseasemean corpuscular hemoglobin concentration

BRIP1 RMND5A SWAP70 KALRN GON4L ABCC5 RRM1 LCP1 FANCG GNA14 PIK3R1 HECW2 EIF2AK4

3.22e-03110514513EFO_0004528
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

MYO5B LCP1

3.88e-03191452EFO_0004612, EFO_0008589
Diseaseovarian neoplasm

BRIP1 POP4 PIK3R1 MLH1

4.39e-031341454C0919267
Diseasehaptoglobin measurement

CHST4 HYDIN

4.74e-03211452EFO_0004640
DiseaseMalignant neoplasm of ovary

BRIP1 POP4 PIK3R1 MLH1

4.74e-031371454C1140680

Protein segments in the cluster

PeptideGeneStartEntry
FNIIKILNNPRAYTL

FAM227B

341

Q96M60
LYLDANQIEELPKQL

ERBIN

51

Q96RT1
PVEQLLFAYKLLDRA

CFAP54

721

Q96N23
RLENAYRAFVPLLKN

CXorf65

86

A6NEN9
DREKELLLLYQAQQP

CCDC33

721

Q8N5R6
PFARYVARNNILNLK

EIF2AK4

1121

Q9P2K8
RQELNTLANPFLAKY

AHSP

71

Q9NZD4
AIQFINQREKPLALY

ALDH3A1

351

P30838
TFYRQALLDSPLNKE

ALMS1

1626

Q8TCU4
NVFVQLPRLQKLYLD

IGFALS

236

P35858
NYEALNAQLLDELPK

DNMBP

1156

Q6XZF7
TNLNDYRENVFKLLP

ANP32A

126

P39687
PDKELSYRQQAANLL

CCNT1

31

O60563
LELLAYLDKSPQFRN

DHX29

851

Q7Z478
GQLLNALLDFQNLYK

DENND3

571

A2RUS2
NLNFLFAPLSKERAQ

CCNYL1

306

Q8N7R7
ALQRRFQKTQYLALP

DLX2

166

Q07687
FQKTQYLALPERAEL

DLX2

171

Q07687
ALQRRFQKTQYLALP

DLX5

151

P56178
FQKTQYLALPERAEL

DLX5

156

P56178
LPKDFMDRNQYALLL

DPP10

551

Q8N608
KPHLIYRQDLNNSFL

ADAMTS20

181

P59510
IKLLDSDQELYRNFP

GRK2

496

P25098
NNSLFLEYSKNPLRE

AMPD3

636

Q01432
RVQLPNNFLKNLEDF

NWD2

1516

Q9ULI1
NYIFLRNAAEELKPR

RAE1

351

P78406
DALQYLLQFARKPVE

INTS4

51

Q96HW7
DQNRVMLKYLFPLNE

GUF1

506

Q8N442
ALENRKEPAALQYIF

PPP2R3C

336

Q969Q6
PVDQFQLYQRLKFER

RNF144B

96

Q7Z419
YNDKIVAFLRQPNIF

HECW2

1081

Q9P2P5
QFYQPKIQQFLRALD

FANCI

921

Q9NVI1
LLTLFNPDLANNYKR

DCAF1

1211

Q9Y4B6
RDLKPENLLIDQQGY

PRKACA

166

P17612
KLRNPYSIDNNELLD

MCTP2

831

Q6DN12
EFKFPNRLNLEAINY

LGALS1

106

P09382
YPNNLNSVLAERLEK

IKBKB

261

O14920
KRNFEHFLLQYLQPR

TRMU

226

O75648
LYLDANQIEELPKQL

LRRC7

51

Q96NW7
LETLDLNYNKLQEFP

LGR6

236

Q9HBX8
LNYNKLQEFPVAIRT

LGR6

241

Q9HBX8
LLQEFATRKPQYEQL

DST

4671

Q03001
LPLAYNDKIVAFLRQ

HECW1

1111

Q76N89
KYQIILARDQFRKNP

FANCM

331

Q8IYD8
KDDLRAYFILLQNPQ

HECTD2

226

Q5U5R9
PNKISALREFLQENY

BEND2

721

Q8NDZ0
KTYFEDNPRDLQLLR

DDX56

461

Q9NY93
ELRLALAQPHNFIYK

FBXW12

76

Q6X9E4
KLNLAFIANLFNRYP

LCP1

361

P13796
NNIFLKELEKYEQLP

KALRN

1341

O60229
FLNALQSPIEYQRKE

KALRN

2231

O60229
NPQRALLYLVAALKE

FANCG

261

O15287
PSDKQRFYTNQLLDV

IRF5

306

Q13568
FDKSIYNVRLLENAP

PCDHA5

241

Q9Y5H7
VLADAFKRYLLDLPN

PIK3R1

181

P27986
LLNPFIYSLRNEKVQ

OR6M1

281

Q8NGM8
PEFYKFLQENDQSLL

NOC2L

81

Q9Y3T9
KQLEDLNILFNENPY

DPRX

26

A6NFQ7
YFLFLNNNFIKRLDP

LRRC70

111

Q7Z2Q7
FPNVKDLQVELKRQY

BRIP1

786

Q9BX63
RYQELLDDNQAPFFL

ABCC5

1076

O15440
LDFQLQDPFLLYRNA

DCP1B

91

Q8IZD4
NKYPSVLNLNEELRD

DAAM1

866

Q9Y4D1
DIQLKYFDLGLPNRD

IDH2

76

P48735
NLLIKFDPSYRNDLN

HYDIN

1121

Q4G0P3
RLLKNDPVNLQKFSY

GRHL3

11

Q8TE85
RDLKPENLLIDQQGY

PRKACG

166

P22612
EKTYRNDPLQDLLFF

DOCK10

61

Q96BY6
QFNPKTYEERINLIL

GNE

436

Q9Y223
RPGFEEQILYLQKQL

GCC2

191

Q8IWJ2
PLREQKDLAFAQAYL

GON4L

1621

Q3T8J9
QLNYFPSKQDILLAR

GNA12

191

Q03113
FNNYRLFPRLQKLLE

ERO1A

56

Q96HE7
AIRLNPDNQYLKVLL

IFIT2

201

P09913
ERIFTKLSYPQDNLQ

GEN1

676

Q17RS7
LLNQLKSFPARLRQY

DYNC1H1

1366

Q14204
QLEALENLFQETKYP

GSC

171

P56915
GNLYLNDSPLKNFRI

GLB1L2

506

Q8IW92
LARADFQKVLQLYPN

FKBP4

371

Q02790
RIEKANNLLYINPEA

FSHR

101

P23945
AAQYPELNALQEELK

GPX6

76

P59796
FNLRELLPKQLGQYF

CA14

196

Q9ULX7
APYRQQLKIINDLLA

DNA2

941

P51530
LDNISPQQIRKLFYV

FANCD2

521

Q9BXW9
PKLRIAAENELNQSY

IPO8

16

O15397
FQSPKDLARYLQELD

FUT3

296

P21217
ARDFILKLYQDQNPD

GNA14

301

O95837
FQLPLRFDLQYKGQA

TARS2

561

Q9BW92
SQIYNIDPARFKDLN

SARS2

281

Q9NP81
PQLDYVFTLAQNLKN

UTRN

2281

P46939
LLALLNKNFDFQRPF

UTS2B

51

Q765I0
KNNPDLYLKELLNLA

TATDN1

86

Q6P1N9
REALQYAKNFQPFAL

RMND5A

211

Q9H871
FVKENLVKLLNPRYN

TOM1L1

96

O75674
RKRPNQALLENIALY

CARS1

536

P49589
YEKIQPLLENLHRNF

TBC1D21

101

Q8IYX1
NYFNVIPKVAFLRLN

KERA

231

O60938
LFALQNLFEEKYAPR

MTR

206

Q99707
QNPKDFQNLLSVYLD

PITRM1

151

Q5JRX3
LFDIKPEQQRYSLFL

POP4

86

O95707
PNLAFIRLNYNKLTD

PRELP

266

P51888
QEAEEFLYRFLPQKI

PSME2

26

Q9UL46
LQLANLPDLYKVFER

MLH1

741

P40692
AAPQRQAYLKFLDQF

OVCA2

211

Q8WZ82
NVLPRDLFQKLFRQD

RPTOR

326

Q8N122
KAYLDIFLPNEQSIR

SNX31

116

Q8N9S9
NLILEERNKYFNPHL

SEMA5A

1041

Q13591
QFKDHPTLNDRYLLL

TLK2

451

Q86UE8
LLKYQDQDFLPRDQH

CCDC15

441

Q0P6D6
KIYIDSNNNPERFLR

CLTC

881

Q00610
RAIQFYLEFKPLLLN

CLTC

1406

Q00610
LKEVRFFNLQSLYPL

CHST4

176

Q8NCG5
LDEKFPQDYRLAQQV

NCAPD2

801

Q15021
LQELYKLNPNFLQLS

CNOT4

241

O95628
FDPRYLLLNSEERKQ

TCERG1L

481

Q5VWI1
SFIENNRLYLPKNEL

TPTE

501

P56180
ALSLKPNDALVYNFR

TTC6

476

Q86TZ1
EFYNGPNRNRLLLKS

SLC16A4

261

O15374
LARFNRVQPQYKLLN

STAU2

16

Q9NUL3
NINYVPLKFRVLFAN

PXMP2

166

Q9NR77
EPNRNEYLELKAKLN

SLITRK5

926

O94991
LLNPKERKQVFDQYV

TCERG1

696

O14776
RYPFESAEAQLLNKQ

RRM1

516

P23921
ALFQKEQLVLALYPQ

SGF29

226

Q96ES7
RQQQYKFLPSELRDE

TLN1

2526

Q9Y490
AELLDLSKQYDQQFP

STX11

6

O75558
IYPNEGFLKQLRELN

STYXL2

261

Q5VZP5
ILLENQLFPDNFAKR

TRAF6

111

Q9Y4K3
EDRKFAPQIRVNLNY

TRPV2

46

Q9Y5S1
LEVLPEYLDRNNKFN

UBR1

446

Q8IWV7
AVPRNNTEDKLYNLL

USP15

596

Q9Y4E8
NTKARLLYEANLPEN

SMAP1

91

Q8IYB5
AEKVANLLQIPQYFD

STAG1

586

Q8WVM7
LNKNNLIPDDRANFY

SEMA5B

1101

Q9P283
QLRTDKNYSFPLNNL

VCPIP1

501

Q96JH7
LYSKQDANQLPRALV

PLCH1

1561

Q4KWH8
LRPSANVYDLAKNFN

ZNFX1

1036

Q9P2E3
DLNIQQNSKYPILFL

TRPV3

641

Q8NET8
EEKPLQIQNDYLFQL

PHLPP1

486

O60346
YTDRVKPLQDQNELF

SF3A3

196

Q12874
PYLNRFILEKVQDNF

SWAP70

71

Q9UH65
VAYAKLRNPFVINDL

PPIP5K2

111

O43314
KITNNIVYFLPRNAD

TGS1

796

Q96RS0
AHKFYLLNIRLPVNE

WLS

191

Q5T9L3
KFENLLNVLEYLALQ

UGT3A2

106

Q3SY77
KDFLEVLINLRNPNY

TBC1D19

156

Q8N5T2
NYKEFSELLPNRQGL

TG

2696

P01266
QEENFLPKYQRVKDL

SULF2

431

Q8IWU5
KLRNPFLINDLAMQY

PPIP5K1

126

Q6PFW1
LRALFQYKPQNVDEL

UBASH3A

281

P57075
VDNVGFNRLLEYLKP

ZBED4

676

O75132
AFPAYLLGINQDRLK

MYO1E

306

Q12965
PNADLAYNSLKRQEL

MYO5B

1191

Q9ULV0
VNLARLAINYDPLEK

MYPN

76

Q86TC9