Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	RNF121 BIRC8 RNF31 MYCBP2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 ZFP91 ASB1 TNFAIP3 HERC2 RFPL2 NSMCE1	4.73e-09	473	189	21	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RNF121 BIRC8 RNF31 MYCBP2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 ZFP91 ASB1 TNFAIP3 HERC2 RFPL2 NSMCE1	1.88e-08	512	189	21	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RNF121 BIRC8 RNF31 MYCBP2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 ZFP91 ASB1 TNFAIP3 HERC2 RFPL2 NSMCE1	3.63e-08	532	189	21	GO:0016755
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	RNF121 BIRC8 RNF31 MYCBP2 RNF213 BIRC5 RFFL RNF43 HERC2P3 TRIM69 TRIM11 HECTD2 DTX4 ASB1 HERC2 RFPL2 NSMCE1	9.94e-08	372	189	17	GO:0061630
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THSD4 RELN VWF LAMA1 LAMC2 COL6A5 SSPOP FBLN2 FBN1 IGFBP6 ACAN MUC5AC	2.43e-07	188	189	12	GO:0005201
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RNF121 BIRC8 RNF31 MYCBP2 RNF213 BIRC5 RFFL RNF43 HERC2P3 TRIM69 TRIM11 HECTD2 DTX4 ASB1 HERC2 RFPL2 NSMCE1	2.59e-07	398	189	17	GO:0061659
GeneOntologyMolecularFunction	acyltransferase activity	RNF121 BIRC8 OGT RNF31 MYCBP2 HECTD4 RNF213 BIRC5 RFFL OSGEP CLOCK RNF43 HERC2P3 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 ZFP91 ASB1 TNFAIP3 HERC2 RFPL2 NSMCE1	3.40e-07	775	189	24	GO:0016746
GeneOntologyMolecularFunction	histone H3T6 kinase activity	PRKCA PRKCB	8.91e-05	2	189	2	GO:0035403
GeneOntologyMolecularFunction	insulin-like growth factor I binding	ITGB4 IGFBP5 IGFBP6	2.23e-04	13	189	3	GO:0031994
GeneOntologyMolecularFunction	ribonucleoside binding	POLR2B POLR1B	2.66e-04	3	189	2	GO:0032549
GeneOntologyMolecularFunction	integrin binding	VWF ECM2 ADAMTS13 ADAM11 ITGB4 FBN1 PRKCA ADAM2	2.68e-04	175	189	8	GO:0005178
GeneOntologyMolecularFunction	transition metal ion binding	DOHH AKAP8 RNF31 MYCBP2 P3H3 BIRC5 ADAMTS13 FBXL19 NPEPL1 SNAI3 TRIM11 ZNF276 TK1 MARCHF3 DTX4 CXXC4 EHMT1 KDM2B PRKCA PRKCB POLR1B TNFAIP3 HERC2 NOS3	3.74e-04	1189	189	24	GO:0046914
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	VLDLR LRP1 LRP6	4.27e-04	16	189	3	GO:0005041
GeneOntologyMolecularFunction	lipoprotein particle receptor binding	RELN AP2A1 LRP1 DNAJA1	4.94e-04	39	189	4	GO:0070325
GeneOntologyMolecularFunction	insulin-like growth factor binding	ITGB4 IGFBP5 IGFBP6	7.23e-04	19	189	3	GO:0005520
GeneOntologyMolecularFunction	calcium ion binding	CAB39 VLDLR PCDHGC4 DSG3 PCDHB5 PCDHB11 ADAMTS13 FBLN2 FBN1 NOTCH2NLB ACAN LRP1 MACF1 EEF2K PADI2 NOTCH2 NOTCH4	7.90e-04	749	189	17	GO:0005509
GeneOntologyMolecularFunction	zinc ion binding	AKAP8 RNF31 MYCBP2 BIRC5 ADAMTS13 FBXL19 TRIM11 ZNF276 TK1 MARCHF3 DTX4 CXXC4 EHMT1 KDM2B PRKCA PRKCB POLR1B TNFAIP3 HERC2	8.24e-04	891	189	19	GO:0008270
GeneOntologyMolecularFunction	apolipoprotein binding	VLDLR LRP1 LRP6	8.45e-04	20	189	3	GO:0034185
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	VLDLR LRP1 LRP6	9.79e-04	21	189	3	GO:0030228
GeneOntologyMolecularFunction	histone H3K27 methyltransferase activity	NSD3 EHMT1	1.30e-03	6	189	2	GO:0046976
GeneOntologyMolecularFunction	histone modifying activity	FBXL19 CLOCK NSD3 EHMT1 KDM2B PRKCA PRKCB PADI2	1.56e-03	229	189	8	GO:0140993
GeneOntologyMolecularFunction	protease binding	CASP8AP2 BIRC8 VWF PSAP RFFL LRP1 TNFAIP3	1.72e-03	181	189	7	GO:0002020
GeneOntologyBiologicalProcess	protein ubiquitination	RNF121 BIRC8 OGT RNF31 MYCBP2 UBD LRRK2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 NOD2 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 SOCS4 ZFP91 ASB1 TNFAIP3 HERC2 DNAJA1 RFPL2	2.50e-08	811	188	26	GO:0016567
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	RNF121 BIRC8 OGT RNF31 MYCBP2 UBD LRRK2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 NOD2 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 SOCS4 ZFP91 ASB1 TNFAIP3 HERC2 DNAJA1 RFPL2 NSMCE1	4.39e-08	893	188	27	GO:0032446
GeneOntologyBiologicalProcess	post-translational protein modification	RNF121 BIRC8 OGT RNF31 MYCBP2 UBD LRRK2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 NOD2 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 SOCS4 ZFP91 PRKCA PRKCB ASB1 TNFAIP3 HERC2 DNAJA1 RFPL2 NSMCE1	1.49e-07	1074	188	29	GO:0043687
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	RNF121 BIRC8 OGT RNF31 MYCBP2 UBD LRRK2 HECTD4 RNF213 BIRC5 RFFL RNF43 HERC2P3 NOD2 TRIM69 TRIM11 HECTD2 MARCHF3 DTX4 SOCS4 ZFP91 ASB1 TNFAIP3 HERC2 DNAJA1 RFPL2 NSMCE1	5.03e-07	1009	188	27	GO:0070647
GeneOntologyBiologicalProcess	regulation of Wnt signaling pathway	BIRC8 SFRP5 LRRK2 RNF213 LGR5 RNF43 IGFBP6 CXXC4 LRP1 LRP6 MACF1 BAMBI TNFAIP3 TBL1X	7.56e-06	368	188	14	GO:0030111
GeneOntologyBiologicalProcess	tissue morphogenesis	SFRP5 LAMA1 EXT2 ZFPM1 STOX1 RREB1 LGR5 TMEFF2 ADAMTS12 SLC39A12 IGFBP5 KDM2B LRP6 MACF1 CSMD1 GRHL3 NOS3 NOTCH2 NOTCH4	5.86e-05	750	188	19	GO:0048729
GeneOntologyBiologicalProcess	negative regulation of non-canonical Wnt signaling pathway	SFRP5 RNF213 LRP6	6.01e-05	9	188	3	GO:2000051
GeneOntologyBiologicalProcess	protein polyubiquitination	RNF31 MYCBP2 RNF213 RFFL NOD2 TRIM11 HECTD2 DTX4 ZFP91 TNFAIP3 RFPL2	7.28e-05	289	188	11	GO:0000209
GeneOntologyBiologicalProcess	Wnt signaling pathway	BIRC8 SFRP5 LRRK2 RNF213 LGR5 RNF43 IGFBP6 CXXC4 LRP1 LRP6 MACF1 BAMBI TNFAIP3 GRHL3 TBL1X	8.14e-05	516	188	15	GO:0016055
GeneOntologyCellularComponent	extracellular matrix	THSD4 RELN VWF PSAP ECM2 LAMA1 LAMC2 COL6A5 ADAMTS13 ADAM11 SSPOP ITGB4 ADAMTS12 FBLN2 FBN1 IGFBP6 ACAN USH2A MUC5AC	8.40e-06	656	189	19	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	THSD4 RELN VWF PSAP ECM2 LAMA1 LAMC2 COL6A5 ADAMTS13 ADAM11 SSPOP ITGB4 ADAMTS12 FBLN2 FBN1 IGFBP6 ACAN USH2A MUC5AC	8.77e-06	658	189	19	GO:0030312
GeneOntologyCellularComponent	collagen-containing extracellular matrix	THSD4 RELN VWF PSAP ECM2 LAMA1 LAMC2 COL6A5 ADAM11 SSPOP ITGB4 FBLN2 FBN1 IGFBP6 ACAN USH2A	2.72e-05	530	189	16	GO:0062023
Domain	EGF_1	VLDLR RELN LAMA1 LAMC2 ADAM29 ADAM11 SSPOP ITGB4 VWDE TMEFF2 FBLN2 FBN1 LRP1 LRP6 ADAM2 USH2A NOTCH2 NOTCH4 PEAR1	7.10e-12	255	182	19	PS00022
Domain	EGF_2	VLDLR RELN LAMA1 LAMC2 ADAM29 ADAM11 SSPOP ITGB4 VWDE TMEFF2 FBLN2 FBN1 LRP1 LRP6 ADAM2 NOTCH2 NOTCH4 PEAR1	1.20e-10	265	182	18	PS01186
Domain	EGF-like_dom	PCSK5 VLDLR RELN LAMA1 LAMC2 ADAM29 ADAM11 VWDE TMEFF2 FBLN2 FBN1 LRP1 LRP6 NOTCH2 NOTCH4 PEAR1	3.02e-09	249	182	16	IPR000742
Domain	EGF-like_CS	VLDLR RELN LAMA1 LAMC2 ADAM29 ADAM11 ITGB4 VWDE TMEFF2 FBLN2 FBN1 LRP1 LRP6 NOTCH2 NOTCH4 PEAR1	5.93e-09	261	182	16	IPR013032
Domain	EGF	PCSK5 VLDLR RELN LAMA1 LAMC2 ADAM11 VWDE TMEFF2 FBLN2 FBN1 LRP1 LRP6 NOTCH2 NOTCH4 PEAR1	1.05e-08	235	182	15	SM00181
Domain	EGF_3	VLDLR RELN ADAM29 ADAM11 SSPOP VWDE TMEFF2 FBLN2 FBN1 LRP1 LRP6 ADAM2 NOTCH2 NOTCH4 PEAR1	1.05e-08	235	182	15	PS50026
Domain	Growth_fac_rcpt_	PCSK5 VLDLR LAMA1 LAMC2 FBXL19 FBLN2 FBN1 IGFBP5 IGFBP6 LRP1 NOTCH2 NOTCH4	4.23e-08	156	182	12	IPR009030
Domain	Znf_RING	RNF121 BIRC8 RNF31 MYCBP2 RNF213 RFFL RNF43 NSD3 TRIM69 TRIM11 MARCHF3 DTX4 RFPL2 NSMCE1	3.97e-06	326	182	14	IPR001841
Domain	VWF_type-D	VWF SSPOP VWDE MUC5AC	1.45e-05	16	182	4	IPR001846
Domain	VWFD	VWF SSPOP VWDE MUC5AC	1.45e-05	16	182	4	PS51233
Domain	VWD	VWF SSPOP VWDE MUC5AC	1.45e-05	16	182	4	SM00216
Domain	VWD	VWF SSPOP VWDE MUC5AC	1.45e-05	16	182	4	PF00094
Domain	DISINTEGRIN_1	ADAM29 ADAMTS13 ADAM11 ADAMTS12 ADAM2	4.15e-05	40	182	5	PS00427
Domain	Reprolysin	ADAM29 ADAMTS13 ADAM11 ADAMTS12 ADAM2	4.15e-05	40	182	5	PF01421
Domain	ADAM_MEPRO	ADAM29 ADAMTS13 ADAM11 ADAMTS12 ADAM2	4.15e-05	40	182	5	PS50215
Domain	DISINTEGRIN_2	ADAM29 ADAMTS13 ADAM11 ADAMTS12 ADAM2	4.15e-05	40	182	5	PS50214
Domain	Peptidase_M12B	ADAM29 ADAMTS13 ADAM11 ADAMTS12 ADAM2	4.15e-05	40	182	5	IPR001590
Domain	RING	RNF121 BIRC8 RNF31 MYCBP2 RNF213 RFFL RNF43 NSD3 TRIM69 TRIM11 DTX4 RFPL2	4.66e-05	305	182	12	SM00184
Domain	Disintegrin_dom	ADAM29 ADAMTS13 ADAM11 ADAMTS12 ADAM2	4.69e-05	41	182	5	IPR001762
Domain	ADAM_Cys-rich	ADAM29 ADAMTS13 ADAM11 ADAM2	1.28e-04	27	182	4	IPR006586
Domain	ACR	ADAM29 ADAMTS13 ADAM11 ADAM2	1.28e-04	27	182	4	SM00608
Domain	ZF_CXXC	FBXL19 CXXC4 KDM2B	1.42e-04	11	182	3	PS51058
Domain	Znf_CXXC	FBXL19 CXXC4 KDM2B	1.42e-04	11	182	3	IPR002857
Domain	zf-CXXC	FBXL19 CXXC4 KDM2B	1.42e-04	11	182	3	PF02008
Domain	-	SHANK1 AGAP5 LRRK2 PPP1R13L EHMT1 ASB1 POTEJ NOTCH2 NOTCH4 PPP1R12C	1.65e-04	248	182	10	1.25.40.20
Domain	Znf_RING/FYVE/PHD	RNF121 BIRC8 MYCBP2 RNF213 RFFL FBXL19 RNF43 NSD3 TRIM69 TRIM11 MARCHF3 DTX4 KDM2B RFPL2	1.69e-04	459	182	14	IPR013083
Domain	ZF_RING_2	RNF121 BIRC8 RNF31 MYCBP2 RNF213 RFFL RNF43 TRIM69 TRIM11 DTX4 RFPL2	1.70e-04	298	182	11	PS50089
Domain	C8	VWF SSPOP MUC5AC	1.88e-04	12	182	3	PF08742
Domain	Quinoprot_gluc/sorb_DH	HHIPL2 LRP1 TBL1X	1.88e-04	12	182	3	IPR011041
Domain	TIL	VWF SSPOP MUC5AC	1.88e-04	12	182	3	PF01826
Domain	EGF_CA	VLDLR FBLN2 FBN1 LRP1 NOTCH2 NOTCH4	1.94e-04	86	182	6	PF07645
Domain	Ankyrin_rpt-contain_dom	SHANK1 AGAP5 LRRK2 PPP1R13L EHMT1 ASB1 POTEJ NOTCH2 NOTCH4 PPP1R12C	2.00e-04	254	182	10	IPR020683
Domain	Unchr_dom_Cys-rich	VWF SSPOP MUC5AC	2.42e-04	13	182	3	IPR014853
Domain	C8	VWF SSPOP MUC5AC	2.42e-04	13	182	3	SM00832
Domain	Ankyrin_rpt	SHANK1 AGAP5 LRRK2 PPP1R13L EHMT1 ASB1 POTEJ NOTCH2 NOTCH4 PPP1R12C	2.57e-04	262	182	10	IPR002110
Domain	Ank_2	SHANK1 AGAP5 PPP1R13L EHMT1 ASB1 POTEJ NOTCH2 NOTCH4 PPP1R12C	2.66e-04	215	182	9	PF12796
Domain	-	POLR2B POLR1B	2.82e-04	3	182	2	2.40.270.10
Domain	RNA_pol_RPB2_OB-fold	POLR2B POLR1B	2.82e-04	3	182	2	IPR014724
Domain	RNA_pol_bsu_CS	POLR2B POLR1B	2.82e-04	3	182	2	IPR007121
Domain	DNA-dir_RNA_pol_su2_6	POLR2B POLR1B	2.82e-04	3	182	2	IPR007120
Domain	RNA_pol_Rpb2_7	POLR2B POLR1B	2.82e-04	3	182	2	PF04560
Domain	RNA_pol_Rpb2_2	POLR2B POLR1B	2.82e-04	3	182	2	PF04561
Domain	RNA_pol_Rpb2_5	POLR2B POLR1B	2.82e-04	3	182	2	PF04567
Domain	RNA_pol_Rpb2_1	POLR2B POLR1B	2.82e-04	3	182	2	PF04563
Domain	RNA_pol_Rpb2_3	POLR2B POLR1B	2.82e-04	3	182	2	PF04565
Domain	RNA_pol_Rpb2_5	POLR2B POLR1B	2.82e-04	3	182	2	IPR007647
Domain	RNA_pol_Rpb2_3	POLR2B POLR1B	2.82e-04	3	182	2	IPR007645
Domain	RNA_pol_bsu_protrusion	POLR2B POLR1B	2.82e-04	3	182	2	IPR007644
Domain	RNA_pol_Rpb2_2	POLR2B POLR1B	2.82e-04	3	182	2	IPR007642
Domain	RNA_pol_Rpb2_7	POLR2B POLR1B	2.82e-04	3	182	2	IPR007641
Domain	Protein_kinase_C_a/b/g	PRKCA PRKCB	2.82e-04	3	182	2	IPR014375
Domain	-	POLR2B POLR1B	2.82e-04	3	182	2	2.40.50.150
Domain	RNA_POL_BETA	POLR2B POLR1B	2.82e-04	3	182	2	PS01166
Domain	-	POLR2B POLR1B	2.82e-04	3	182	2	3.90.1110.10
Domain	DNA-dir_RNA_pol_su2	POLR2B POLR1B	2.82e-04	3	182	2	IPR015712
Domain	RNA_pol_Rpb2_6	POLR2B POLR1B	2.82e-04	3	182	2	PF00562
Domain	PHD_4	FBXL19 KDM2B	2.82e-04	3	182	2	PF16866
Domain	LUC7	LUC7L LUC7L2	2.82e-04	3	182	2	PF03194
Domain	Luc7-rel	LUC7L LUC7L2	2.82e-04	3	182	2	IPR004882
Domain	TIL_dom	VWF SSPOP MUC5AC	3.06e-04	14	182	3	IPR002919
Domain	Ldl_recept_b	VLDLR LRP1 LRP6	3.06e-04	14	182	3	PF00058
Domain	LDLRB	VLDLR LRP1 LRP6	3.06e-04	14	182	3	PS51120
Domain	Galactose-bd-like	PCSK5 MYCBP2 LAMA1 SSPOP MKLN1 HERC2	3.16e-04	94	182	6	IPR008979
Domain	zf-C3HC4	RNF121 BIRC8 RNF213 RNF43 TRIM69 TRIM11 MARCHF3 DTX4 RFPL2	3.48e-04	223	182	9	PF00097
Domain	EGF_Lam	LAMA1 LAMC2 USH2A PEAR1	3.61e-04	35	182	4	SM00180
Domain	Laminin_EGF	LAMA1 LAMC2 USH2A PEAR1	3.61e-04	35	182	4	PF00053
Domain	EGF_Ca-bd_CS	VLDLR FBLN2 FBN1 LRP1 NOTCH2 NOTCH4	3.74e-04	97	182	6	IPR018097
Domain	LY	VLDLR LRP1 LRP6	3.80e-04	15	182	3	SM00135
Domain	LDLR_classB_rpt	VLDLR LRP1 LRP6	3.80e-04	15	182	3	IPR000033
Domain	VWFC_1	VWF ECM2 SSPOP MUC5AC	4.03e-04	36	182	4	PS01208
Domain	EGF_CA	VLDLR FBLN2 FBN1 LRP1 NOTCH2 NOTCH4	4.17e-04	99	182	6	PS01187
Domain	ASX_HYDROXYL	VLDLR FBLN2 FBN1 LRP1 NOTCH2 NOTCH4	4.40e-04	100	182	6	PS00010
Domain	Disintegrin_CS	ADAM29 ADAM11 ADAM2	4.64e-04	16	182	3	IPR018358
Domain	-	RNF121 MYCBP2 RNF213 RFFL FBXL19 RNF43 NSD3 TRIM69 TRIM11 MARCHF3 DTX4 KDM2B RFPL2	4.74e-04	449	182	13	3.30.40.10
Domain	VWFC_2	VWF ECM2 SSPOP MUC5AC	4.97e-04	38	182	4	PS50184
Domain	VWC	VWF ECM2 SSPOP MUC5AC	4.97e-04	38	182	4	SM00214
Domain	Laminin_EGF	LAMA1 LAMC2 USH2A PEAR1	4.97e-04	38	182	4	IPR002049
Domain	Pep_M12B_propep	ADAM29 ADAM11 ADAMTS12 ADAM2	5.50e-04	39	182	4	PF01562
Domain	Peptidase_M12B_N	ADAM29 ADAM11 ADAMTS12 ADAM2	5.50e-04	39	182	4	IPR002870
Domain	-	VLDLR HHIPL2 LRP1 LRP6	5.50e-04	39	182	4	2.120.10.30
Domain	Notch	NOTCH2 NOTCH4	5.59e-04	4	182	2	IPR008297
Domain	NODP	NOTCH2 NOTCH4	5.59e-04	4	182	2	PF07684
Domain	Notch_NODP_dom	NOTCH2 NOTCH4	5.59e-04	4	182	2	IPR011656
Domain	Notch_NOD_dom	NOTCH2 NOTCH4	5.59e-04	4	182	2	IPR010660
Domain	NOD	NOTCH2 NOTCH4	5.59e-04	4	182	2	PF06816
Domain	NOD	NOTCH2 NOTCH4	5.59e-04	4	182	2	SM01338
Domain	NODP	NOTCH2 NOTCH4	5.59e-04	4	182	2	SM01339
Domain	ZF_RING_1	RNF121 BIRC8 RNF31 MYCBP2 RFFL RNF43 TRIM69 TRIM11 DTX4 RFPL2	5.87e-04	291	182	10	PS00518
Domain	EGF-type_Asp/Asn_hydroxyl_site	VLDLR FBLN2 FBN1 LRP1 NOTCH2 NOTCH4	6.01e-04	106	182	6	IPR000152
Domain	LDLR_class-A_CS	VLDLR SSPOP LRP1 LRP6	6.06e-04	40	182	4	IPR023415
Domain	CTCK_1	VWF SSPOP MUC5AC	6.67e-04	18	182	3	PS01185
Domain	ADAM_CR	ADAM29 ADAM11 ADAM2	6.67e-04	18	182	3	PF08516
Domain	-	PCSK5 MYCBP2 SSPOP MKLN1 HERC2	7.31e-04	73	182	5	2.60.120.260
Domain	VWF_dom	VWF ECM2 SSPOP MUC5AC	7.31e-04	42	182	4	IPR001007
Domain	Leu-rich_rpt_Cys-con_subtyp	FBXL13 FBXL19 KDM2B	7.86e-04	19	182	3	IPR006553
Domain	LRR_CC	FBXL13 FBXL19 KDM2B	7.86e-04	19	182	3	SM00367
Domain	VWC_out	VWF SSPOP MUC5AC	7.86e-04	19	182	3	SM00215
Domain	PLAC	THSD4 PCSK5 ADAMTS12	7.86e-04	19	182	3	PS50900
Domain	PLAC	THSD4 PCSK5 ADAMTS12	7.86e-04	19	182	3	IPR010909
Domain	ANK	SHANK1 AGAP5 PPP1R13L EHMT1 ASB1 POTEJ NOTCH2 NOTCH4 PPP1R12C	8.16e-04	251	182	9	SM00248
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	THSD4 GNE EXT2 ADAMTS13 SSPOP ADAMTS12 ACAN MUC5AC NOTCH2 NOTCH4	1.20e-06	143	136	10	M27275
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	THSD4 ADAMTS13 SSPOP ADAMTS12 MUC5AC NOTCH2 NOTCH4	3.96e-06	68	136	7	M27303
Pathway	PID_NFKAPPAB_CANONICAL_PATHWAY	SSPOP NOD2 PRKCA TNFAIP3	6.36e-05	23	136	4	M37
Pathway	WP_FOCAL_ADHESION	RELN VWF LAMA1 LAMC2 ITGB4 CCND3 PRKCA PRKCB PPP1R12C	1.33e-04	199	136	9	M39402
Pathway	PID_INTEGRIN4_PATHWAY	LAMA1 LAMC2 ITGB4	1.37e-04	11	136	3	M158
Pathway	REACTOME_DISEASES_OF_METABOLISM	THSD4 GNE EXT2 ADAMTS13 SSPOP ADAMTS12 ACAN MUC5AC NOTCH2 NOTCH4	1.55e-04	250	136	10	M27554
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	VWF P3H3 LAMA1 LAMC2 COL6A5 ITGB4 FBLN2 FBN1 ACAN PRKCA KLKB1	1.55e-04	300	136	11	M610
Pathway	PID_RAS_PATHWAY	NF1 PRKCA PRKCB PLCE1	1.87e-04	30	136	4	M269
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA1 LAMC2 ITGB4 PRKCA	2.73e-04	33	136	4	M39503
Pathway	REACTOME_WNT5A_DEPENDENT_INTERNALIZATION_OF_FZD4	AP2A1 PRKCA PRKCB	3.67e-04	15	136	3	M27413
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTS13 SSPOP ADAMTS12	5.25e-04	39	136	4	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	THSD4 ADAMTS13 SSPOP ADAMTS12	5.25e-04	39	136	4	MM15165
Pathway	BIOCARTA_CCR5_PATHWAY	PRKCA PRKCB CCR5	5.41e-04	17	136	3	M2349
Pathway	REACTOME_TRAFFICKING_OF_GLUR2_CONTAINING_AMPA_RECEPTORS	AP2A1 PRKCA PRKCB	5.41e-04	17	136	3	M5488
Pathway	KEGG_WNT_SIGNALING_PATHWAY	SFRP5 CCND3 CXXC4 LRP6 PRKCA PRKCB TBL1X	6.49e-04	151	136	7	M19428
Pathway	KEGG_FOCAL_ADHESION	RELN VWF LAMA1 LAMC2 ITGB4 CCND3 PRKCA PRKCB	6.90e-04	199	136	8	M7253
Pathway	REACTOME_DISEASES_OF_HEMOSTASIS	VWF ADAMTS13 KLKB1	7.60e-04	19	136	3	M48230
Pathway	BIOCARTA_CCR5_PATHWAY	PRKCA PRKCB CCR5	7.60e-04	19	136	3	MM1453
Pathway	WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3	TLR8 NOD2 PRKCA PRKCB PLCE1	7.80e-04	75	136	5	M39568
Pathway	WP_WNT_SIGNALING_WP428	SFRP5 CCND3 CXXC4 LRP6 PRKCA PRKCB	7.84e-04	113	136	6	M39669
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR5 RNF43 LRP6	8.88e-04	20	136	3	MM15155
Pathway	BIOCARTA_ION_PATHWAY	PRKCA PRKCB	9.07e-04	5	136	2	MM1574
Pathway	BIOCARTA_PLCD_PATHWAY	PRKCA PRKCB	9.07e-04	5	136	2	MM1587
Pathway	BIOCARTA_ION_PATHWAY	PRKCA PRKCB	9.07e-04	5	136	2	M22059
Pathway	BIOCARTA_PLCD_PATHWAY	PRKCA PRKCB	9.07e-04	5	136	2	M22080
Pathway	REACTOME_REELIN_SIGNALLING_PATHWAY	VLDLR RELN	9.07e-04	5	136	2	M27759
Pathway	REACTOME_DISINHIBITION_OF_SNARE_FORMATION	PRKCA PRKCB	9.07e-04	5	136	2	M26920
Pathway	REACTOME_REELIN_SIGNALLING_PATHWAY	VLDLR RELN	9.07e-04	5	136	2	MM15504
Pathway	REACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3	NOTCH2 NOTCH4	9.07e-04	5	136	2	M27411
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMA1 LAMC2 ITGB4 PRKCA	9.88e-04	46	136	4	M239
Pathway	REACTOME_REGULATION_OF_FZD_BY_UBIQUITINATION	LGR5 RNF43 LRP6	1.03e-03	21	136	3	M27401
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PCSK5 TBKBP1 RHBDF1 MYCBP2 DUSP5 KIAA0319L HECTD4 POLRMT PER1 ZFPM1 FBXL19 ITGB4 CDPF1 RNF43 NSD3 NOD2 CCND3 DIP2A ZNF276 AATK AP2A1 ZBED4 CHST15 DIAPH2 EHMT1 DIP2C BAMBI WDR90 TNFAIP3 HERC2 NOTCH2 GAREM1	1.42e-14	1105	191	32	35748872
Pubmed	A new PKCα/β/TBX3/E-cadherin pathway is involved in PLCε-regulated invasion and migration in human bladder cancer cells.	PRKCA PRKCB PLCE1	1.63e-07	3	191	3	24316392
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	VLDLR OGT AKAP8 RNF31 P3H3 POLR2B POLRMT PER1 RNF213 RREB1 RNF43 NSD3 LUC7L2 ZFP91 LRP1 EHMT1 MACF1 CSMD1 DNAJA1 PADI2 NOTCH2 NSMCE1	2.52e-07	1116	191	22	31753913
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	SHANK1 VWF MYCBP2 TACC2 PPP1R13L RUSC2 LUC7L KANSL2 FBLN2 FBN1 NF1 IGFBP6 LUC7L2 NOTCH2 PPP1R12C	5.60e-07	560	191	15	21653829
Pubmed	Rapid activation of CLOCK by Ca2+-dependent protein kinase C mediates resetting of the mammalian circadian clock.	PER1 CLOCK PRKCA	6.50e-07	4	191	3	17347670
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	PCSK5 BIRC8 POLR2B FBXL19 NSD3 CCND3 ADAMTS12 AP2A1 MAP4K1 AK5 LRP1 EHMT1 PRKCA PRKCB ADAM2 DNAH5 TBL1X	6.75e-07	730	191	17	34857952
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	SHANK1 VLDLR RELN OGT VWF PSAP MYCBP2 KIAA0319L HECTD4 DDIT4L METTL26 DIP2A KANSL2 FBN1 TTC7B AP2A1 HECTD2 MKLN1 LRP1 MACF1 HERC2 DNAJA1 PADI2	7.08e-07	1285	191	23	35914814
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	PSAP LAMA1 COL6A5 ADAM11 SSPOP FBLN2	1.46e-06	64	191	6	22261194
Pubmed	Role of two conserved cytoplasmic threonine residues (T410 and T412) in CD5 signaling.	CD5 PRKCA PRKCB	1.62e-06	5	191	3	11123317
Pubmed	Intersectin 1 is a component of the Reelin pathway to regulate neuronal migration and synaptic plasticity in the hippocampus.	VLDLR RELN AP2A1	3.22e-06	6	191	3	28484035
Pubmed	Protein kinase C isoenzymes differentially regulate the differentiation-dependent expression of adhesion molecules in human epidermal keratinocytes.	DSG3 PRKCA PRKCB	3.22e-06	6	191	3	18637128
Pubmed	Interaction between Reelin and Notch signaling regulates neuronal migration in the cerebral cortex.	VLDLR RELN NOTCH2	3.22e-06	6	191	3	18957219
Pubmed	Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.	OGT AKAP8 POLR2B ZFPM1 RREB1 EHMT1 POLR1B DNAJA1	6.59e-06	177	191	8	26206133
Pubmed	Maturation of human dendritic cells is accompanied by functional remodelling of the ubiquitin-proteasome system.	FBXL13 UBD RNF213 FBXL19 TRIM69 HECTD2	7.74e-06	85	191	6	19028597
Pubmed	Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2.	VLDLR RELN LRP1	8.95e-06	8	191	3	10380922
Pubmed	Rescue of ataxia and preplate splitting by ectopic expression of Reelin in reeler mice.	VLDLR RELN ACAN	8.95e-06	8	191	3	11856531
Pubmed	Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.	LAMA1 FBN1 ACAN NOTCH4	1.40e-05	27	191	4	35894043
Pubmed	Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.	RNF31 MYCBP2 HECTD4 RNF213 HECTD2 HERC2	1.47e-05	95	191	6	29643511
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	THSD4 MYCBP2 TMEFF2 NOD2 TYRP1 LPP TNFAIP3 CSMD1 GAREM1	1.74e-05	265	191	9	19240061
Pubmed	Notch signaling in stomach epithelial stem cell homeostasis.	LGR5 MUC5AC NOTCH2 NOTCH4	1.88e-05	29	191	4	21402740
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	FBXL19 CXXC4 KDM2B	1.90e-05	10	191	3	29276034
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	CAB39 DENND4A VWF PSAP MYCBP2 OSGEP LUC7L IGFBP5 MKLN1 MACF1 NOTCH2 PLCE1	2.19e-05	497	191	12	23414517
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 OGT AKAP8 MYCBP2 HECTD4 NF1 AP2A1 DIAPH2 LRP1 EHMT1 PRKCA PRKCB MACF1 HERC2 DNAJA1 UNC79 TBL1X	2.58e-05	963	191	17	28671696
Pubmed	Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol.	PRKCA PRKCB GRHL3	2.60e-05	11	191	3	14613966
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	RELN MYCBP2 LRP6	2.60e-05	11	191	3	23968836
Pubmed	Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.	THSD4 OGT DUSP5 RNF213 AP2A1 ARNT2 LRP1 DNAH5	2.61e-05	214	191	8	22199357
Pubmed	Plasma ADAMTS13 activity and von Willebrand factor antigen and activity in patients with subarachnoid haemorrhage.	VWF ADAMTS13	3.00e-05	2	191	2	28102428
Pubmed	N-Glycans of ADAMTS13 modulate its secretion and von Willebrand factor cleaving activity.	VWF ADAMTS13	3.00e-05	2	191	2	18981290
Pubmed	The proximal carboxyl-terminal domains of ADAMTS13 determine substrate specificity and are all required for cleavage of von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	15975930
Pubmed	Confocal laser scanning analysis of the association of fibulin-2 with fibrillin-1 and fibronectin define different stages of skin regeneration.	FBLN2 FBN1	3.00e-05	2	191	2	9886271
Pubmed	Platelet-free shear flow assay facilitates analysis of shear-dependent functions of VWF and ADAMTS13.	VWF ADAMTS13	3.00e-05	2	191	2	25201004
Pubmed	Interactions of von Willebrand factor and ADAMTS13 in von Willebrand disease and thrombotic thrombocytopenic purpura.	VWF ADAMTS13	3.00e-05	2	191	2	25010251
Pubmed	Protein kinase C-alpha phosphorylation of specific serines in the connecting segment of the beta 4 integrin regulates the dynamics of type II hemidesmosomes.	ITGB4 PRKCA	3.00e-05	2	191	2	15121854
Pubmed	Heterogeneity of cellular proliferation within transitional cell carcinoma: correlation of protein kinase C alpha/betaI expression and activity.	PRKCA PRKCB	3.00e-05	2	191	2	16517978
Pubmed	Von Willebrand factor and ADAMTS13: a candidate couple for preeclampsia pathophysiology.	VWF ADAMTS13	3.00e-05	2	191	2	21512165
Pubmed	Von Willebrand Factor, ADAMTS13 and D-Dimer Are Correlated with Different Levels of Nephropathy in Type 1 Diabetes Mellitus.	VWF ADAMTS13	3.00e-05	2	191	2	26168189
Pubmed	Multi-step binding of ADAMTS-13 to von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	19765212
Pubmed	Variations in the ratio between von Willebrand factor and its cleaving protease during systemic inflammation and association with severity and prognosis of organ failure.	VWF ADAMTS13	3.00e-05	2	191	2	19190805
Pubmed	Increased plasma von Willebrand factor antigen levels but normal von Willebrand factor cleaving protease (ADAMTS13) activity in preeclampsia.	VWF ADAMTS13	3.00e-05	2	191	2	19190814
Pubmed	Calcium-dependent isoforms of protein kinase C mediate posttetanic potentiation at the calyx of Held.	PRKCA PRKCB	3.00e-05	2	191	2	21658591
Pubmed	ADAMTS13 and von Willebrand factor and the risk of myocardial infarction in men.	VWF ADAMTS13	3.00e-05	2	191	2	17053057
Pubmed	Oxidative modification of von Willebrand factor by neutrophil oxidants inhibits its cleavage by ADAMTS13.	VWF ADAMTS13	3.00e-05	2	191	2	19812385
Pubmed	Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.	VWF ADAMTS13	3.00e-05	2	191	2	16141351
Pubmed	Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13).	VWF ADAMTS13	3.00e-05	2	191	2	21705658
Pubmed	Insights Into Immunothrombosis: The Interplay Among Neutrophil Extracellular Trap, von Willebrand Factor, and ADAMTS13.	VWF ADAMTS13	3.00e-05	2	191	2	33343584
Pubmed	von Willebrand factor self-association is regulated by the shear-dependent unfolding of the A2 domain.	VWF ADAMTS13	3.00e-05	2	191	2	30936056
Pubmed	Impact of mutations in the von Willebrand factor A2 domain on ADAMTS13-dependent proteolysis.	VWF ADAMTS13	3.00e-05	2	191	2	16322474
Pubmed	An autoantibody epitope comprising residues R660, Y661, and Y665 in the ADAMTS13 spacer domain identifies a binding site for the A2 domain of VWF.	VWF ADAMTS13	3.00e-05	2	191	2	20032502
Pubmed	Development of a Hyperactive Primary Hemostatic System During Off-Pump Lung Transplantation Resulting From an Unbalance Between von Willebrand Factor and Its Cleaving Protease ADAMTS13.	VWF ADAMTS13	3.00e-05	2	191	2	25846964
Pubmed	Transient activation of PKC results in long-lasting detrimental effects on systolic [Ca2+]i in cardiomyocytes by altering actin cytoskeletal dynamics and T-tubule integrity.	PRKCA PRKCB	3.00e-05	2	191	2	29307535
Pubmed	The Role of von Willebrand Factor, ADAMTS13, and Cerebral Artery Thrombus Composition in Patient Outcome Following Mechanical Thrombectomy for Acute Ischemic Stroke.	VWF ADAMTS13	3.00e-05	2	191	2	29887594
Pubmed	Force-induced cleavage of single VWFA1A2A3 tridomains by ADAMTS-13.	VWF ADAMTS13	3.00e-05	2	191	2	19897584
Pubmed	Impact of the von Willebrand factor-ADAMTS-13 axis on the risk of future venous thromboembolism.	VWF ADAMTS13	3.00e-05	2	191	2	36736832
Pubmed	Genes encoding catalytic subunits of protein kinase A and risk of spina bifida.	PRKCA PRKCB	3.00e-05	2	191	2	16080189
Pubmed	Traumatic injury results in prolonged circulation of ultralarge von Willebrand factor and a reduction in ADAMTS13 activity.	VWF ADAMTS13	3.00e-05	2	191	2	32441353
Pubmed	Lung Inflammatory Phenotype in Mice Deficient in Fibulin-2 and ADAMTS-12.	ADAMTS12 FBLN2	3.00e-05	2	191	2	38396702
Pubmed	ADAMTS-13 metalloprotease interacts with the endothelial cell-derived ultra-large von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	12775718
Pubmed	Altered von Willebrand Factor and ADAMTS13 Levels in Children With Cirrhosis and Extrahepatic Portal Hypertension.	VWF ADAMTS13	3.00e-05	2	191	2	33369998
Pubmed	Identification of ADAMTS13 peptide sequences binding to von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	19944670
Pubmed	ADAMTS-13 cleaves long von Willebrand factor multimeric strings anchored to endothelial cells in the absence of flow, platelets or conformation-altering chemicals.	VWF ADAMTS13	3.00e-05	2	191	2	18983500
Pubmed	Generation of a poor prognostic chronic lymphocytic leukemia-like disease model: PKCα subversion induces up-regulation of PKCβII expression in B lymphocytes.	PRKCA PRKCB	3.00e-05	2	191	2	25616575
Pubmed	Activity of Von Willebrand factor and levels of VWF-cleaving protease (ADAMTS13) in preterm and full term neonates.	VWF ADAMTS13	3.00e-05	2	191	2	28087247
Pubmed	ADAMTS-13-VWF axis in sickle cell disease patients.	VWF ADAMTS13	3.00e-05	2	191	2	33404693
Pubmed	No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse.	PER1 CLOCK	3.00e-05	2	191	2	12511614
Pubmed	Molecular mapping of the chloride-binding site in von Willebrand factor (VWF): energetics and conformational effects on the VWF/ADAMTS-13 interaction.	VWF ADAMTS13	3.00e-05	2	191	2	16899464
Pubmed	von Willebrand factor and its cleaving protease ADAMTS13 balance in coronary artery vessels: Lessons learned from thrombotic thrombocytopenic purpura. A narrative review.	VWF ADAMTS13	3.00e-05	2	191	2	28521259
Pubmed	Binding of ADAMTS13 to von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	15824096
Pubmed	Allele-dependent interaction of LRRK2 and NOD2 in leprosy.	LRRK2 NOD2	3.00e-05	2	191	2	36972292
Pubmed	Cleavage of ultra-large von Willebrand factor by ADAMTS-13 under flow conditions.	VWF ADAMTS13	3.00e-05	2	191	2	16102037
Pubmed	The expression of ADAMTS13 in human microvascular endothelial cells.	VWF ADAMTS13	3.00e-05	2	191	2	26366828
Pubmed	Relationship between ADAMTS13 activity, von Willebrand factor antigen levels and platelet function in the early and late phases after TIA or ischaemic stroke.	VWF ADAMTS13	3.00e-05	2	191	2	25498844
Pubmed	Exome sequencing identified new mutations in a Marfan syndrome family.	FBN1 LRP1	3.00e-05	2	191	2	24484584
Pubmed	Cigarette smoke-induced alterations in endothelial nitric oxide synthase phosphorylation: role of protein kinase C.	PRKCA NOS3	3.00e-05	2	191	2	17922342
Pubmed	LRRK2 G2019S Induces Anxiety/Depression-like Behavior before the Onset of Motor Dysfunction with 5-HT1A Receptor Upregulation in Mice.	HTR1A LRRK2	3.00e-05	2	191	2	29305532
Pubmed	N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.	VWF ADAMTS13	3.00e-05	2	191	2	21266777
Pubmed	Behavior of ADAMTS13 and Von Willebrand factor levels in patients after living donor liver transplantation.	VWF ADAMTS13	3.00e-05	2	191	2	23266519
Pubmed	Degradation of circulating von Willebrand factor and its regulator ADAMTS13 implicates secreted Bacillus anthracis metalloproteases in anthrax consumptive coagulopathy.	VWF ADAMTS13	3.00e-05	2	191	2	18263586
Pubmed	An amino acid polymorphism in von Willebrand factor correlates with increased susceptibility to proteolysis by ADAMTS13.	VWF ADAMTS13	3.00e-05	2	191	2	14525793
Pubmed	Identification of rare missense mutations in NOTCH2 and HERC2 associated with familial central precocious puberty via whole-exome sequencing.	HERC2 NOTCH2	3.00e-05	2	191	2	32400230
Pubmed	Levels of von Willebrand factor antigen and von Willebrand factor cleaving protease (ADAMTS13) activity predict clinical events in chronic heart failure.	VWF ADAMTS13	3.00e-05	2	191	2	19718479
Pubmed	A model for the conformational activation of the structurally quiescent metalloprotease ADAMTS13 by von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	28209710
Pubmed	Epithelial-mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC-α and βI isozymes.	PRKCA PRKCB	3.00e-05	2	191	2	21323641
Pubmed	Pathophysiology of thrombotic thrombocytopenic purpura.	VWF ADAMTS13	3.00e-05	2	191	2	20058209
Pubmed	Levels and activities of von Willebrand factor and metalloproteinase with thrombospondin type-1 motif, number 13 in inflammatory bowel diseases.	VWF ADAMTS13	3.00e-05	2	191	2	28765701
Pubmed	The O-linked glycans of human von Willebrand factor modulate its interaction with ADAMTS-13.	VWF ADAMTS13	3.00e-05	2	191	2	24406064
Pubmed	Protein kinase C alpha, betaI, and betaII isozymes regulate cytokine production in mast cells through MEKK2/ERK5-dependent and -independent pathways.	PRKCA PRKCB	3.00e-05	2	191	2	16430878
Pubmed	Update on ADAMTS13 and VWF in cardiovascular and hematological disorders.	VWF ADAMTS13	3.00e-05	2	191	2	27746209
Pubmed	Suppression of PKC causes oncogenic stress for triggering apoptosis in cancer cells.	PRKCA PRKCB	3.00e-05	2	191	2	28415683
Pubmed	The effect of exercise on von Willebrand factor and ADAMTS-13 in individuals with type 1 and type 2B von Willebrand disease.	VWF ADAMTS13	3.00e-05	2	191	2	17922807
Pubmed	Acquired von Willebrand factor deficiency caused by LVAD is ADAMTS-13 and platelet dependent.	VWF ADAMTS13	3.00e-05	2	191	2	26616301
Pubmed	Characterization of a core binding site for ADAMTS-13 in the A2 domain of von Willebrand factor.	VWF ADAMTS13	3.00e-05	2	191	2	17121983
Pubmed	PPAPDC1B and WHSC1L1 are common drivers of the 8p11-12 amplicon, not only in breast tumors but also in pancreatic adenocarcinomas and lung tumors.	PLPP5 NSD3	3.00e-05	2	191	2	24051013
Pubmed	High VWF, low ADAMTS13, and oral contraceptives increase the risk of ischemic stroke and myocardial infarction in young women.	VWF ADAMTS13	3.00e-05	2	191	2	22110247
Pubmed	von Willebrand factor cleaved from endothelial cells by ADAMTS13 remains ultralarge in size.	VWF ADAMTS13	3.00e-05	2	191	2	19682236
Pubmed	Increased VWF antigen levels and decreased ADAMTS13 activity in preeclampsia.	VWF ADAMTS13	3.00e-05	2	191	2	23433535
Pubmed	cPKC-dependent sequestration of membrane-recycling components in a subset of recycling endosomes.	PRKCA PRKCB	3.00e-05	2	191	2	14527960
Pubmed	Genome-wide expression profiling identifies an impairment of negative feedback signals in the Crohn's disease-associated NOD2 variant L1007fsinsC.	NOD2 TNFAIP3	3.00e-05	2	191	2	21335489
Pubmed	N-linked glycan stabilization of the VWF A2 domain.	VWF ADAMTS13	3.00e-05	2	191	2	26773038
Pubmed	ADAMTS13 reduces VWF-mediated acute inflammation following focal cerebral ischemia in mice.	VWF ADAMTS13	3.00e-05	2	191	2	22712744
Pubmed	Selective loss of basal but not receptor-stimulated relaxation by endothelial nitric oxide synthase after isolation of the mouse aorta.	FBN1 NOS3	3.00e-05	2	191	2	23022329
Interaction	TOP3B interactions	PCSK5 TBKBP1 RHBDF1 MYCBP2 DUSP5 KIAA0319L HECTD4 POLRMT PER1 ZFPM1 FBXL19 ITGB4 CDPF1 RNF43 NSD3 NOD2 CCND3 DIP2A ZNF276 AATK AP2A1 ZBED4 CHST15 DIAPH2 EHMT1 DIP2C BAMBI WDR90 TNFAIP3 HERC2 DNAJA1 NOTCH2 GAREM1	1.45e-06	1470	185	33	int:TOP3B
Interaction	IGFL3 interactions	PCSK5 VLDLR MYCBP2 LAMA1 ADAM11 VWDE NOTCH2	5.75e-06	75	185	7	int:IGFL3
GeneFamily	Ring finger proteins	RNF121 RNF31 RNF213 RFFL RNF43 TRIM69 TRIM11 MARCHF3 DTX4 RFPL2	3.44e-05	275	132	10	58
GeneFamily	Ankyrin repeat domain containing	SHANK1 AGAP5 PPP1R13L EHMT1 ASB1 POTEJ NOTCH2 NOTCH4 PPP1R12C	7.23e-05	242	132	9	403
GeneFamily	Zinc fingers CXXC-type	FBXL19 CXXC4 KDM2B	7.98e-05	12	132	3	136
GeneFamily	Low density lipoprotein receptors	VLDLR LRP1 LRP6	1.03e-04	13	132	3	634
GeneFamily	F-box and leucine rich repeat proteins	FBXL13 FBXL19 KDM2B	4.59e-04	21	132	3	558
GeneFamily	NLR family	NOD2 NLRP14 NLRP5	7.78e-04	25	132	3	666
GeneFamily	Insulin like growth factor binding proteins	IGFBP5 IGFBP6	7.78e-04	6	132	2	1065
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ADAM29 ADAM11 ADAM2	9.79e-04	27	132	3	47
GeneFamily	Ring finger proteins\|Baculoviral IAP repeat containing\|Caspase recruitment domain containing	BIRC8 BIRC5	1.44e-03	8	132	2	419
GeneFamily	C2 domain containing protein kinases	PRKCA PRKCB	2.29e-03	10	132	2	835
GeneFamily	Laminin subunits	LAMA1 LAMC2	3.33e-03	12	132	2	626
Coexpression	NABA_ECM_GLYCOPROTEINS	THSD4 VWA3A RELN VWF ECM2 LAMA1 LAMC2 SSPOP VWDE FBLN2 FBN1 IGFBP5 IGFBP6 USH2A	1.77e-10	196	189	14	M3008
Coexpression	NABA_CORE_MATRISOME	THSD4 VWA3A RELN VWF ECM2 LAMA1 LAMC2 COL6A5 SSPOP VWDE FBLN2 FBN1 IGFBP5 IGFBP6 ACAN USH2A	1.82e-10	275	189	16	M5884
Coexpression	NABA_CORE_MATRISOME	THSD4 VWA3A RELN VWF ECM2 LAMA1 LAMC2 COL6A5 SSPOP VWDE FBLN2 FBN1 IGFBP5 IGFBP6 ACAN	1.30e-09	270	189	15	MM17057
Coexpression	NABA_ECM_GLYCOPROTEINS	THSD4 VWA3A RELN VWF ECM2 LAMA1 LAMC2 SSPOP VWDE FBLN2 FBN1 IGFBP5 IGFBP6	1.46e-09	191	189	13	MM17059
Coexpression	NABA_MATRISOME	THSD4 VWA3A PCSK5 RELN SFRP5 VWF PLXDC1 P3H3 ECM2 LAMA1 LAMC2 ADAM29 COL6A5 ADAMTS13 ADAM11 SSPOP VWDE ADAMTS12 FBLN2 FBN1 IGFBP5 IGFBP6 ACAN ZFP91 ADAM2 USH2A MUC5AC	6.39e-09	1026	189	27	M5889
Coexpression	NABA_MATRISOME	THSD4 VWA3A PCSK5 RELN SFRP5 VWF PLXDC1 P3H3 ECM2 LAMA1 LAMC2 ADAM29 COL6A5 ADAMTS13 ADAM11 SSPOP VWDE ADAMTS12 FBLN2 FBN1 IGFBP5 IGFBP6 ACAN ADAM2 MUC5AC	7.70e-08	1008	189	25	MM17056
Coexpression	GSE22935_WT_VS_MYD88_KO_MACROPHAGE_48H_MBOVIS_BCG_STIM_UP	ITGB4 AATK TTC7B IGFBP5 CHST15 AK5 ZFP91 KLHL23 PADI2 ANO3	1.97e-06	199	189	10	M7766
Coexpression	GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP	PCSK5 HECTD4 NF1 LPP DIAPH2 PRKCA PRKCB HERC2 NSMCE1	1.39e-05	197	189	9	M7403
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY3_DN	RHBDF1 KIAA0319L POLRMT ADAM11 METTL26 SLC39A12 CHST15 EEF2K PADI2	1.57e-05	200	189	9	M6583
Coexpression	GSE18791_UNSTIM_VS_NEWCATSLE_VIRUS_DC_2H_DN	DENND4A ADAM11 FBXL19 HERC2P3 IGFBP5 POLR1B RFPL2 GAREM1	5.75e-05	183	189	8	M4289
Coexpression	BERNARD_PPAPDC1B_TARGETS_DN	SUSD4 PLPP5 NSD3 IGFBP5 PLCE1	6.75e-05	59	189	5	M8123
Coexpression	KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_DN	BIRC5 IGFBP5 IGFBP6 TK1 PRKCA	7.93e-05	61	189	5	M16639
Coexpression	GSE21546_SAP1A_KO_VS_SAP1A_KO_AND_ELK1_KO_DP_THYMOCYTES_DN	MROH2A PCDHB11 NSD3 CCND3 PRKCA TNFAIP3 NSMCE1 CDCA4	1.03e-04	199	189	8	M7524
Coexpression	GSE2826_WT_VS_BTK_KO_BCELL_UP	VWF LAMA1 NPEPL1 CXCR5 NUDT5 LPP NOTCH4 NSMCE1	1.07e-04	200	189	8	M4898
Coexpression	GSE5589_IL6_KO_VS_IL10_KO_LPS_AND_IL10_STIM_MACROPHAGE_45MIN_UP	P3H3 PCDHB11 PER1 TACC2 RUSC2 EHMT1 PRKCB TNFAIP3	1.07e-04	200	189	8	M6655
Coexpression	HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	ECM2 LAMA1 LAMC2 FBLN2 FBN1 LRP1 TNFAIP3 NOTCH2	1.07e-04	200	189	8	M5930
Coexpression	GSE17721_0.5H_VS_12H_GARDIQUIMOD_BMDC_DN	RNF121 RFFL TLR8 RUSC2 LUC7L ZBED4 SOCS4 DNAJA1	1.07e-04	200	189	8	M4136
Coexpression	GSE7460_CTRL_VS_FOXP3_OVEREXPR_TCONV_DN	DENND4A KIAA0319L METTL26 TLR8 NF1 LRP6 EEF2K TNFAIP3	1.07e-04	200	189	8	M5715
Coexpression	MANALO_HYPOXIA_UP	VLDLR VWF PPP1R13L CHST15 MARCHF3 DIAPH2 TNFAIP3 NOTCH4	1.27e-04	205	189	8	M259
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2C	THSD4 VWA3A RELN PCDHGC4 LAMA1 BIRC5 FBLN2 LRP1 PRKCA CSMD1	1.33e-04	325	189	10	M39053
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MROH2A LAMA1 SSPOP CSMD1 DNAH5 USH2A UNC79 ANO3 PLCE1	7.57e-09	184	191	10	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MROH2A LAMA1 SSPOP CSMD1 DNAH5 USH2A UNC79 ANO3 PLCE1	7.57e-09	184	191	10	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN MROH2A LAMA1 SSPOP CSMD1 DNAH5 USH2A UNC79 ANO3 PLCE1	7.57e-09	184	191	10	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SUSD4 VWF MROH2A ITGB4 IGFBP5 TTLL6 AK5 NOS3	9.29e-08	181	191	9	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	LV-07._Pericyte\|LV / Chamber and Cluster_Paper	PLXDC1 SLC16A12 ADAMTS12 IGFBP5 LPP KLHL23 DIAPH2 PEAR1 PLCE1	1.12e-07	185	191	9	acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCell	droplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 VWF ECM2 LGR5 ITGB4 FBLN2 FBN1 NOS3 NOTCH4	1.23e-07	187	191	9	e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 VWF ITGB4 TMEFF2 FBLN2 FBN1 CD5 CXXC4 NOS3	1.34e-07	189	191	9	d17e8467699c7ca7694a313c26111f085df5204e
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN SUSD4 ECM2 MROH2A LGR5 SLC16A12 IGFBP5 PEAR1 PLCE1	1.40e-07	190	191	9	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN SUSD4 ECM2 MROH2A LGR5 SLC16A12 IGFBP5 PEAR1 PLCE1	1.40e-07	190	191	9	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RELN SUSD4 ECM2 MROH2A LGR5 SLC16A12 IGFBP5 PEAR1 PLCE1	1.40e-07	190	191	9	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	VWF DUSP5 IGFBP5 CHST15 MARCHF3 TNFAIP3 DNAJA1 NOTCH4 PEAR1	1.47e-07	191	191	9	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	LRRK2 TACC2 FBLN2 ARNT2 LRP1 LRP6 BAMBI CSMD1 UNC79	2.08e-07	199	191	9	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SUSD4 MROH2A CDKL1 SLC16A12 IGFBP5 TTLL6 AK5	9.23e-07	175	191	8	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_3\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	DUSP5 RUSC2 EIF2D CHST15 PRKCB POLR1B NOTCH4 GAREM1	1.01e-06	177	191	8	eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ADAM11 CDKL1 TYRP1 AATK ARNT2 CSMD1 GRHL3	1.05e-06	178	191	8	ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAT3 PLXDC1 P3H3 FBXL19 CD5 KLHL23 PRKCA ZKSCAN4	1.09e-06	179	191	8	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ADAM11 TYRP1 AATK ARNT2 CSMD1 GRHL3 UNC79	1.24e-06	182	191	8	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ADAM11 TYRP1 AATK ARNT2 CSMD1 GRHL3 UNC79	1.24e-06	182	191	8	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	droplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SUSD4 ECM2 MROH2A LGR5 SLC16A12 PEAR1 PLCE1	1.40e-06	185	191	8	3a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCell	droplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SUSD4 ECM2 MROH2A LGR5 SLC16A12 PEAR1 PLCE1	1.40e-06	185	191	8	224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 VWF TACC2 FBXL19 PPP1R13L ITGB4 FBLN2 FBN1	1.46e-06	186	191	8	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	Endothelial-Endothelial-E\|Endothelial / shred on cell class and cell subclass (v4)	VWF P3H3 ITGB4 FBLN2 FBN1 IGFBP5 EEF2K NOS3	1.58e-06	188	191	8	2777eb7689b271c199021fe7d9db88ccebff14de
ToppCell	LPS_only-Endothelial-Endothelial-Artery\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 VWF ITGB4 FBLN2 FBN1 CSMD1 NOS3 NOTCH4	1.64e-06	189	191	8	b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Artery\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 VWF ITGB4 FBLN2 FBN1 CSMD1 NOS3 NOTCH4	1.71e-06	190	191	8	aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDIT4L SLC16A12 AATK IGFBP5 ACAN LPP KLHL23 PLCE1	1.78e-06	191	191	8	5c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Artery\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PCSK5 VWF ITGB4 FBLN2 FBN1 CSMD1 NOS3 NOTCH4	1.78e-06	191	191	8	4b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCell	facs-Heart-LV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RHBDF1 PLXDC1 ECM2 DDIT4L FBN1 IGFBP6 LPP KLHL23	1.78e-06	191	191	8	b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDIT4L SLC16A12 AATK IGFBP5 ACAN LPP KLHL23 PLCE1	1.85e-06	192	191	8	eb9a0b3d32f90f8b95905c740aab21639dae5cbd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	VLDLR LAMA1 DDIT4L LGR5 RNF43 SLC16A12 SLC5A3 TYRP1	1.85e-06	192	191	8	ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTS12 FBN1 IGFBP5 CHST15 LRP1 PRKCA PRKCB	2.00e-06	194	191	8	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTS12 FBN1 IGFBP5 CHST15 LRP1 PRKCA PRKCB	2.00e-06	194	191	8	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	THSD4 P3H3 ECM2 DUSP5 IGFBP5 KLHL23 PEAR1 PLCE1	2.08e-06	195	191	8	6e875c83f838241b5fcaf4a3249b1408d74521dc
ToppCell	COVID-19-kidney-PLVAP+EC\|kidney / Disease (COVID-19 only), tissue and cell type	VWF DUSP5 IGFBP5 CHST15 MARCHF3 MACF1 NOS3 NOTCH4	2.08e-06	195	191	8	a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 ADAMTS12 FBN1 IGFBP5 CHST15 LRP1 PRKCA PRKCB	2.08e-06	195	191	8	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	tumor_Lung-Fibroblasts-Myofibroblasts\|tumor_Lung / Location, Cell class and cell subclass	P3H3 ECM2 ADAMTS12 FBLN2 FBN1 IGFBP5 IGFBP6 LRP1	2.33e-06	198	191	8	31f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCell	distal-mesenchymal-Myofibroblast-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ECM2 LGR5 TYRP1 FBN1 IGFBP5 IGFBP6 CXXC4 ANO3	2.33e-06	198	191	8	beef5075ba6dcd4d0a447bc4e57efcaf2e93c546
ToppCell	facs-Trachea-nan-3m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK5 VLDLR P3H3 ECM2 FBLN2 FBN1 IGFBP6 LRP1	2.33e-06	198	191	8	0dc7d59a07428a7b7e8bdc81f0e2417dd4ce3cf2
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SFRP5 PLXDC1 ITGB4 ADAMTS12 FBN1 IGFBP5 IGFBP6 ACAN	2.41e-06	199	191	8	45c3b853900d8c3d5965117d904e3714100138bc
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Artery\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	PCSK5 VLDLR VWF ITGB4 FBLN2 FBN1 CSMD1 NOS3	2.51e-06	200	191	8	ac9ead34afa14067171833f5c277eaf06db7b02e
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	THSD4 PCSK5 TACC2 ADAMTS13 FBN1 IGFBP5 HECTD2 LPP	2.51e-06	200	191	8	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CASP8AP2 VWF DUSP5 IGFBP5 POTEJ NOS3 NOTCH4	5.08e-06	156	191	7	f894fac4e44a23718b20ad80c9677bf4f2118002
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEFF2 FBLN2 FBN1 IGFBP5 IGFBP6 ZNF641 ANO3	6.51e-06	162	191	7	56f1789e69a6cb29956e46aba92b290847327c1f
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN SUSD4 MROH2A ITGB4 MARCHF3 HHIPL2 PLCE1	7.06e-06	164	191	7	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN SUSD4 MROH2A ITGB4 MARCHF3 HHIPL2 PLCE1	7.06e-06	164	191	7	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN SUSD4 MROH2A ITGB4 MARCHF3 HHIPL2 PLCE1	7.06e-06	164	191	7	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RELN SUSD4 MROH2A ITGB4 MARCHF3 HHIPL2 PLCE1	7.06e-06	164	191	7	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	facs-Limb_Muscle-forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ECM2 FBLN2 FBN1 IGFBP6 LRP1 MUC5AC SEC14L5	7.34e-06	165	191	7	f80665b75d43f1bf6919d59fc762e7e0bac653f2
ToppCell	droplet-Heart-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR ECM2 PER1 IGFBP5 LRP1 BAMBI NOTCH2	8.59e-06	169	191	7	2e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UBD MROH2A IGFBP6 DNAH5 USH2A KLKB1 UNC79	8.59e-06	169	191	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	THSD4 RELN SUSD4 ECM2 CD5 DIAPH2 PEAR1	9.63e-06	172	191	7	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-SMG_basal_2\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	UBD LAMA1 STOX1 LGR5 NOD2 CHST15 UNC79	1.08e-05	175	191	7	4462000b22af227555413ba202a872868eecde6c
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF ECM2 LGR5 ITGB4 FBLN2 AATK NOS3	1.25e-05	179	191	7	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 VWF ZNF416 FBLN2 CSMD1 NOS3 PEAR1	1.25e-05	179	191	7	d2db9e70b780643f1e004c41a70464d0abe26088
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 DDIT4L SSPOP SLC16A12 AATK KLHL23 PEAR1	1.34e-05	181	191	7	06174ce9240c9261c0f51a1b0d875335d60722e5
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 ECM2 COL6A5 ADAMTS12 FBN1 LRP1 PEAR1	1.34e-05	181	191	7	c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLXDC1 ECM2 COL6A5 ADAMTS12 FBN1 LRP1 PEAR1	1.34e-05	181	191	7	c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCell	facs-Heart-LV-3m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLXDC1 DDIT4L SSPOP SLC16A12 AATK KLHL23 PEAR1	1.34e-05	181	191	7	1db1eb7d330a7e5090994007ae287e11f0a74450
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	OGT RNF213 NOTCH2NLB LPP MKLN1 MACF1 TNFAIP3	1.34e-05	181	191	7	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 VWF UBD TACC2 ITGB4 FBLN2 NOS3	1.39e-05	182	191	7	ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 VWF UBD TACC2 ITGB4 FBLN2 NOS3	1.39e-05	182	191	7	47ff6b4002a4167412c79210651316d1342503f9
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ADAM11 TYRP1 AATK ARNT2 CSMD1 UNC79	1.44e-05	183	191	7	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	PLXDC1 SLC16A12 ADAMTS12 IGFBP5 KLHL23 PEAR1 PLCE1	1.44e-05	183	191	7	273db6a3b00a93ca852498471187b642b5368185
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ADAM11 TYRP1 AATK ARNT2 CSMD1 UNC79	1.44e-05	183	191	7	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 VWF P3H3 ITGB4 FBLN2 FBN1 NOS3	1.49e-05	184	191	7	8bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	SUSD4 PLXDC1 SLC16A12 ADAMTS12 KLHL23 DIAPH2 PLCE1	1.49e-05	184	191	7	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFRP5 ADAM11 TYRP1 AATK ARNT2 CSMD1 UNC79	1.49e-05	184	191	7	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOHH ECM2 BIRC5 SLC44A4 NUDT5 TK1 CCR5	1.49e-05	184	191	7	a0831e850bc0b585296ed350fdd075c1f730308e
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 VWF P3H3 ITGB4 FBLN2 FBN1 NOS3	1.49e-05	184	191	7	f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCell	droplet-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN PCDHB5 STOX1 SLC16A12 FBLN2 CD5 PLCE1	1.55e-05	185	191	7	6a85399cfdb9b89683c874e7f046957f9a601dc2
ToppCell	droplet-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN PCDHB5 STOX1 SLC16A12 FBLN2 CD5 PLCE1	1.55e-05	185	191	7	64791056cdbb739136dbef08f4b16e2b5427faad
ToppCell	droplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TMEFF2 FBN1 IGFBP6 AK5 LRP1 CSMD1	1.60e-05	186	191	7	94d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PSAP LRRK2 DIAPH2 LRP1 CSMD1 USH2A TBL1X	1.60e-05	186	191	7	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RHBDF1 P3H3 ECM2 PCDHB11 FBLN2 FBN1 IGFBP6	1.66e-05	187	191	7	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RHBDF1 DSG3 RNF213 FBXL19 PPP1R13L ITGB4 SLC5A3	1.66e-05	187	191	7	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 LRRK2 CLOCK EIF2D ARNT2 NOTCH2	1.71e-05	188	191	7	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 LRRK2 CLOCK EIF2D ARNT2 NOTCH2	1.71e-05	188	191	7	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	THSD4 PCSK5 LRRK2 CLOCK EIF2D ARNT2 NOTCH2	1.71e-05	188	191	7	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TMEFF2 FBLN2 FBN1 IGFBP5 IGFBP6 LRP1	1.71e-05	188	191	7	2cfa41c64eccb28b5e22f0f91bbc921b75713245
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLXDC1 P3H3 ECM2 DUSP5 KLHL23 PEAR1 PLCE1	1.71e-05	188	191	7	a906c29e3fda22eecfec3e5cac706c417bf2b7a4
ToppCell	10x3'2.3-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	PLXDC1 TMEFF2 FBLN2 FBN1 IGFBP5 IGFBP6 CSMD1	1.71e-05	188	191	7	0e2d1b21f0a7ee306e7dae16fc8c19d16a467883
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF ITGB4 FBLN2 FBN1 CSMD1 NOS3 NOTCH4	1.77e-05	189	191	7	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 RNF213 LAMC2 CCND3 WFDC5 DNAH5 GAREM1	1.77e-05	189	191	7	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TMEFF2 FBLN2 FBN1 IGFBP5 IGFBP6 LRP1	1.77e-05	189	191	7	56f43e00d81cf3cdf0c39f8d7120f5beab72e258
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRK2 RNF213 LAMC2 CCND3 WFDC5 DNAH5 GAREM1	1.77e-05	189	191	7	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 FBLN2 FBN1 IGFBP6 LRP1	1.83e-05	190	191	7	bd0d68dc1b6f388190a6ba8a83b011619abe2bdd
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 FBLN2 FBN1 IGFBP6 LRP1	1.83e-05	190	191	7	e275de94468872e70cf305b3b450823d4c9c5e3f
ToppCell	droplet-Mammary_Gland-nan-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 FBLN2 FBN1 IGFBP6 LRP1	1.83e-05	190	191	7	ee2f4a55d2fd18b83e55399b5b5697a15a2d2e70
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 FBLN2 FBN1 IGFBP6 LRP1	1.83e-05	190	191	7	47077579496c5340e99f61499427a3a36b566da3
ToppCell	droplet-Kidney-nan-3m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 ADAMTS12 FBN1 IGFBP6 AK5	1.83e-05	190	191	7	f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCell	droplet-Kidney-nan-3m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 ADAMTS12 FBN1 IGFBP6 AK5	1.83e-05	190	191	7	2abeb013bb83c578e67dcb985ba44ca63134950b
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLXDC1 P3H3 ECM2 DUSP5 KLHL23 PEAR1 PLCE1	1.83e-05	190	191	7	951e067d14412db67dc3babcdf61e41717d7b429
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 FBLN2 FBN1 IGFBP6 LRP1	1.90e-05	191	191	7	a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	VLDLR ADAMTS12 FBN1 CHST15 LRP1 MACF1 NOTCH2	1.90e-05	191	191	7	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR P3H3 COL6A5 TMEFF2 FBLN2 AK5 LRP1	1.90e-05	191	191	7	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR P3H3 COL6A5 TMEFF2 FBLN2 AK5 LRP1	1.90e-05	191	191	7	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VLDLR P3H3 COL6A5 TMEFF2 FBLN2 AK5 LRP1	1.90e-05	191	191	7	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 ECM2 TMEFF2 FBLN2 FBN1 IGFBP6 LRP1	1.90e-05	191	191	7	19c67a812b8ce97472d316acd15aeefe8736000d
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TMEFF2 FBLN2 FBN1 IGFBP5 IGFBP6 LRP1	1.90e-05	191	191	7	1b26056df078674f37a6c06f6256b30cfcec21a7
ToppCell	droplet-Kidney-nan-18m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	P3H3 TMEFF2 FBN1 IGFBP6 AK5 LRP1 CSMD1	1.96e-05	192	191	7	38d7a24ae205ef91ed2e0f402d8022f2a9cdb243
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	THSD4 PLXDC1 ADAMTS12 FBN1 CHST15 LRP1 ANO3	1.96e-05	192	191	7	bc84b9ce01b4d826a682842ab8a395dac9b91183
Disease	Malignant neoplasm of breast	SFRP5 VWF ADAT3 AKAP8 UBD PER1 BIRC5 TACC2 CXCR5 SLC39A12 NLRP14 NF1 IGFBP5 EHMT1 DIP2C MACF1 HERC2 NOS3 NOTCH2 NOTCH4	1.37e-05	1074	184	20	C0006142
Disease	Colorectal Carcinoma	SHANK1 SFRP5 LAMA1 PER1 BIRC5 ADAM29 SLC44A4 LGR5 RNF43 FBLN2 NF1 TK1 LRP1 DIP2C PRKCB	3.74e-05	702	184	15	C0009402
Disease	congestive heart failure (biomarker_via_orthology)	OGT BIRC5 ACAN PRKCA PRKCB NOS3	5.81e-05	107	184	6	DOID:6000 (biomarker_via_orthology)
Disease	Behcet's disease (is_implicated_in)	VWF NOD2 CCR5 NOS3	7.37e-05	36	184	4	DOID:13241 (is_implicated_in)
Disease	Alzheimer's disease (is_marker_for)	RELN HTR1A STOX1 PRKCB EEF2K CCR5 ADAM2 NOS3	2.22e-04	257	184	8	DOID:10652 (is_marker_for)
Disease	skin pigmentation measurement	ADAMTS12 TYRP1 ZNF276 FBN1 HERC2 USH2A	2.27e-04	137	184	6	EFO_0007009
Disease	Herlitz Disease	LAMC2 ITGB4	2.30e-04	4	184	2	C0079683
Disease	Epidermolysis Bullosa Progressiva	LAMC2 ITGB4	2.30e-04	4	184	2	C0079297
Disease	nevus count, cutaneous melanoma	TYRP1 TTC7B MKLN1 HERC2 NOTCH2	2.69e-04	91	184	5	EFO_0000389, EFO_0004632
Disease	psoriasis	FBXL19 RUSC2 TYRP1 TNFAIP3 CSMD1 GRHL3 ANO3 NOTCH4	3.33e-04	273	184	8	EFO_0000676
Disease	Colorectal Neoplasms	SFRP5 LAMA1 BIRC5 LGR5 RNF43 FBLN2 TK1 PRKCB	3.67e-04	277	184	8	C0009404
Disease	anti-human herpes virus 7 antibody measurement	TBKBP1 CXCR5	3.82e-04	5	184	2	EFO_0011038
Disease	Adult junctional epidermolysis bullosa (disorder)	LAMC2 ITGB4	3.82e-04	5	184	2	C0268374
Disease	EPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)	LAMC2 ITGB4	3.82e-04	5	184	2	C2608084
Disease	junctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)	LAMC2 ITGB4	3.82e-04	5	184	2	DOID:0060738 (implicated_via_orthology)
Disease	arginine measurement	LAMC2 CSMD1 KLKB1	3.85e-04	23	184	3	EFO_0020990
Disease	nighttime rest measurement	LYZL4 CSMD1 NSMCE1	4.38e-04	24	184	3	EFO_0007827
Disease	Alzheimer's disease (implicated_via_orthology)	LRP1 CCR5 DNAJA1 NOTCH4	4.47e-04	57	184	4	DOID:10652 (implicated_via_orthology)
Disease	alpha-linolenic acid measurement	SFRP5 CSMD1 NLRP5	4.96e-04	25	184	3	EFO_0007759
Disease	severe acute respiratory syndrome, COVID-19	THSD4 RELN P3H3 ADAMTS12 ARNT2 MKLN1 DIAPH2 PRKCA CSMD1 TBL1X	5.31e-04	447	184	10	EFO_0000694, MONDO_0100096
Disease	diabetes mellitus (implicated_via_orthology)	OGT CLOCK LRP1	5.58e-04	26	184	3	DOID:9351 (implicated_via_orthology)
Disease	Junctional Epidermolysis Bullosa	LAMC2 ITGB4	5.71e-04	6	184	2	C0079301
Disease	hypertension	HECTD4 RNF213 COL6A5 SLC44A4 RNF43 SLC39A12 NOS3 PLCE1	7.21e-04	307	184	8	EFO_0000537
Disease	junctional epidermolysis bullosa (is_implicated_in)	LAMC2 ITGB4	7.96e-04	7	184	2	DOID:3209 (is_implicated_in)
Disease	stem cell growth factor-alpha measurement	SHANK1 UBD	7.96e-04	7	184	2	EFO_0020754
Disease	interstitial lung disease	HTR1A CSMD1 MUC5AC NOTCH4	8.26e-04	67	184	4	EFO_0004244
Disease	Hyperglycemia, Postprandial	FBN1 PRKCB NOS3	8.56e-04	30	184	3	C1855520
Disease	Hyperglycemia	FBN1 PRKCB NOS3	8.56e-04	30	184	3	C0020456
Disease	spontaneous coronary artery dissection	THSD4 FBN1 LRP1	9.43e-04	31	184	3	EFO_0010820
Disease	JT interval	ZFPM1 CDPF1 SLC16A12 TTC7B LPP PRKCA CLUH	9.75e-04	248	184	7	EFO_0007885
Disease	body fat percentage	RELN HTR1A ACAN AK5 MARCHF3 LRP1 PRKCA MACF1 UNC79 PLCE1	1.04e-03	488	184	10	EFO_0007800
Disease	cervix carcinoma (is_marker_for)	CCND3 TK1	1.06e-03	8	184	2	DOID:2893 (is_marker_for)
Disease	mesangial proliferative glomerulonephritis (biomarker_via_orthology)	VWF FBN1	1.06e-03	8	184	2	DOID:4783 (biomarker_via_orthology)
Disease	liver cirrhosis (biomarker_via_orthology)	FBN1 KLKB1 NOS3	1.24e-03	34	184	3	DOID:5082 (biomarker_via_orthology)
Disease	childhood onset asthma	PSAP PLXDC1 NOD2 CXCR5 TYRP1 LPP MKLN1 LRP1	1.24e-03	334	184	8	MONDO_0005405
Disease	stem Cell Growth Factor beta measurement	SHANK1 PCSK5 UBD KLKB1	1.26e-03	75	184	4	EFO_0008292
Disease	Schizophrenia	SHANK1 VLDLR RELN HTR1A LAMA1 CLOCK ADAMTS12 LRP1 KDM2B PRKCA CCR5 ZKSCAN4 CSMD1 NOTCH4	1.35e-03	883	184	14	C0036341
Disease	pulmonary sarcoidosis (is_implicated_in)	NOD2 CCR5	1.35e-03	9	184	2	DOID:13406 (is_implicated_in)
Disease	susceptibility to shingles measurement	TBKBP1 OR2B3 ZKSCAN4 NOTCH4	1.67e-03	81	184	4	EFO_0008401
Disease	aortic aneurysm	FBN1 LRP1	1.68e-03	10	184	2	EFO_0001666
Disease	Asthma, Occupational	PRKCA HERC2	1.68e-03	10	184	2	C0264423
Disease	dry eye syndrome (is_marker_for)	CCR5 MUC5AC	1.68e-03	10	184	2	DOID:10140 (is_marker_for)
Disease	age at onset, multiple sclerosis	PCSK5 RELN	1.68e-03	10	184	2	EFO_0004847, MONDO_0005301
Disease	interventricular septum thickness	CDPF1 KDM2B	1.68e-03	10	184	2	EFO_0009287
Disease	Cardiomegaly	PRKCA PRKCB BAMBI NOS3	1.75e-03	82	184	4	C0018800
Disease	Cardiac Hypertrophy	PRKCA PRKCB BAMBI NOS3	1.75e-03	82	184	4	C1383860
Disease	Autism Spectrum Disorders	RELN DIP2A USH2A TBL1X	2.00e-03	85	184	4	C1510586
Disease	aortic valve stenosis (is_marker_for)	OGT BAMBI	2.05e-03	11	184	2	DOID:1712 (is_marker_for)
Disease	pigmentation disease (is_implicated_in)	TYRP1 HERC2	2.05e-03	11	184	2	DOID:10123 (is_implicated_in)
Disease	gastric adenocarcinoma (is_implicated_in)	RNF43 PLCE1	2.05e-03	11	184	2	DOID:3717 (is_implicated_in)
Disease	peptidyl-glycine alpha-amidating monooxygenase measurement	MYCBP2 KLKB1	2.05e-03	11	184	2	EFO_0801871
Disease	sleep disorder (implicated_via_orthology)	CLOCK NF1	2.05e-03	11	184	2	DOID:535 (implicated_via_orthology)
Disease	orofacial cleft, sex interaction measurement	NF1 LPP NOTCH4 PLCE1	2.09e-03	86	184	4	EFO_0008343, MONDO_0000358
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	RELN HTR1A ACAN AK5 LRP1 MACF1 UNC79 PLCE1	2.12e-03	364	184	8	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	carotid artery intima media thickness	THSD4 HTR1A LRRK2 TACC2 VWDE FBN1 TTC7B ARNT2 LRP1	2.16e-03	450	184	9	EFO_0007117
Disease	Calcium channel blocker use measurement	RNF213 SLC44A4 ZFP91 KDM2B NOS3 PLCE1	2.26e-03	213	184	6	EFO_0009930
Disease	descending aortic diameter	CDPF1 FBN1 LRP1 PLCE1	2.27e-03	88	184	4	EFO_0021788
Disease	smoking status measurement, chronic obstructive pulmonary disease	THSD4 UBD RREB1 ZKSCAN4	2.27e-03	88	184	4	EFO_0000341, EFO_0006527
Disease	Secondary Biliary Cholangitis	UBD CXCR5 NOS3	2.29e-03	42	184	3	C0238065
Disease	Biliary cirrhosis	UBD CXCR5 NOS3	2.29e-03	42	184	3	C0023892
Disease	Biliary Cirrhosis, Primary, 1	UBD CXCR5 NOS3	2.29e-03	42	184	3	C4551595
Disease	Amelogenesis Imperfecta	LAMC2 ITGB4	2.45e-03	12	184	2	C0002452
Disease	right ventricular stroke volume measurement	LUC7L2 NOS3	2.45e-03	12	184	2	EFO_0021817
Disease	dementia (is_implicated_in)	VLDLR NOTCH4	2.45e-03	12	184	2	DOID:1307 (is_implicated_in)
Disease	autistic disorder (is_marker_for)	VLDLR RELN	2.45e-03	12	184	2	DOID:12849 (is_marker_for)
Disease	dickkopf‐related protein 1 measurement	ZFPM1 PEAR1	2.45e-03	12	184	2	EFO_0010620
Disease	body surface area	PCSK5 PER1 RREB1 CDPF1 CCND3 FBLN2 FBN1 AATK ACAN MACF1 UNC79	2.46e-03	643	184	11	EFO_0022196
Disease	Hereditary Diffuse Gastric Cancer	HTR1A BIRC5 RNF43 PRKCB NOS3 NOTCH2 PLCE1	2.52e-03	293	184	7	C1708349
Disease	eye colour measurement	MYCBP2 TYRP1 ARNT2 WFDC5 HERC2 USH2A	2.54e-03	218	184	6	EFO_0009764
Disease	daytime rest measurement	HTR1A MYCBP2 LRRK2 AATK CHST15 PRKCA PRKCB	2.61e-03	295	184	7	EFO_0007828
Disease	Stomach Neoplasms	HTR1A BIRC5 RNF43 PRKCB NOS3 NOTCH2 PLCE1	2.71e-03	297	184	7	C0038356
Disease	Malignant neoplasm of stomach	HTR1A BIRC5 RNF43 PRKCB NOS3 NOTCH2 PLCE1	2.87e-03	300	184	7	C0024623
Disease	hypertension (biomarker_via_orthology)	VWF RFFL CLOCK FBN1 CCR5 NOS3	3.10e-03	227	184	6	DOID:10763 (biomarker_via_orthology)
Disease	Adenocarcinoma of large intestine	RNF43 PRKCA PRKCB EEF2K	3.11e-03	96	184	4	C1319315
Disease	systemic lupus erythematosus (is_marker_for)	ADAMTS13 NOD2 CCR5	3.16e-03	47	184	3	DOID:9074 (is_marker_for)
Disease	Primary biliary cirrhosis	UBD CXCR5 NOS3	3.16e-03	47	184	3	C0008312
Disease	response to 5-fluorouracil, response to cyclophosphamide, chemotherapy-induced alopecia, response to doxorubicin	VSIG2 CSMD1	3.35e-03	14	184	2	EFO_0005400, GO_0036275, GO_1902518, GO_1902520
Disease	Arthritis, Psoriatic	FBXL19 NOD2	3.35e-03	14	184	2	C0003872
Disease	cannabis dependence measurement	DIP2A CSMD1 ANO3	3.36e-03	48	184	3	EFO_0008457
Disease	cholestasis (biomarker_via_orthology)	ADAMTS13 CLOCK NOS3	3.56e-03	49	184	3	DOID:13580 (biomarker_via_orthology)
Disease	Thrombosis	VWF ADAMTS13 KLKB1	3.56e-03	49	184	3	C0040053
Disease	status epilepticus (biomarker_via_orthology)	RELN ACAN PRKCB CCR5	3.60e-03	100	184	4	DOID:1824 (biomarker_via_orthology)
Disease	chronotype measurement	RELN FBXL13 MYCBP2 PER1 LAMC2 SLC44A4 AK5 LPP ZFP91 CXXC4 DIP2C ASB1 CSMD1	3.72e-03	882	184	13	EFO_0008328
Disease	malaria	CHST15 DIP2C TNFAIP3 CSMD1	3.87e-03	102	184	4	EFO_0001068
Disease	Major Depressive Disorder	RELN HTR1A AKAP8 CLOCK LRP1 PRKCB	4.32e-03	243	184	6	C1269683
Disease	cortical thickness	THSD4 RELN FBXL13 MYCBP2 LAMA1 PCDHB11 TACC2 STOX1 RREB1 CLOCK FBN1 LRP1 MACF1 CLUH PLCE1	4.32e-03	1113	184	15	EFO_0004840
Disease	2-hydroxyglutarate measurement	VSIG2 ZFP91	4.38e-03	16	184	2	EFO_0021506
Disease	Pre-Eclampsia	STOX1 NOS3	4.38e-03	16	184	2	C0032914
Disease	urinary bladder cancer (is_marker_for)	BIRC5 CCND3 PRKCA NOS3	4.58e-03	107	184	4	DOID:11054 (is_marker_for)
Disease	leukemia	PPP1R13L FANCE NF1	4.93e-03	55	184	3	C0023418
Disease	Necrotizing Enterocolitis	SNAI3 NOS3	4.95e-03	17	184	2	C0520459
Disease	Moyamoya Disease	RNF213 NF1	4.95e-03	17	184	2	C0026654
Disease	phosphatidylcholine 40:6 measurement	NOD2 CSMD1	4.95e-03	17	184	2	EFO_0010389
Disease	cervical artery dissection	LRP1 PLCE1	4.95e-03	17	184	2	EFO_1000059
Disease	a disintegrin and metalloproteinase with thrombospondin motifs 13 measurement	ADAMTS13 KLKB1	4.95e-03	17	184	2	EFO_0008011
Disease	serum gamma-glutamyl transferase measurement	THSD4 HECTD4 ZFPM1 FBXL19 RREB1 CDPF1 NF1 ZFP91 KDM2B CSMD1 NOTCH2 TBL1X PLCE1	4.99e-03	914	184	13	EFO_0004532
Disease	ovarian cancer (is_implicated_in)	NOD2 PRKCA NOS3	5.19e-03	56	184	3	DOID:2394 (is_implicated_in)
Disease	Glioblastoma Multiforme	NF1 PRKCA PRKCB NOTCH2	5.22e-03	111	184	4	C1621958
Disease	attempted suicide	PCSK5 FBN1 KLHL23 CSMD1 ANO3	5.28e-03	178	184	5	EFO_0004321
Disease	Psoriasis	FBXL19 TNFAIP3 CSMD1	5.45e-03	57	184	3	C0033860

Protein segments in the cluster

Peptide	Gene	Start	Entry
CACTPERMAEAGFIH	BIRC5	31	O15392
MVGENTTLRCCLSPE	BTN2A3P	41	Q96KV6
TCRCSQPRCIMHEGN	ADAM29	346	Q9UKF5
CADNPLLHAVMVCVD	ADAT3	216	Q96EY9
HMFSCCPEGRQLDIK	EIF2D	296	P41214
MELLCCEGTRHAPRA	CCND3	1	P30281
PVAITMCEFLGLAHC	CXCR5	301	P32302
CEMGHQLRGSPERTC	CSMD1	2946	Q96PZ7
IEAAHCLACDMLIPA	AKAP8	476	O43823
CSGAVCIMNPEAIHF	ADAM2	331	Q99965
PGCVMDAVLRHGCEA	ASB1	236	Q9Y576
DGTACGPNMLCLDHR	ADAM11	651	O75078
ASRNPTFMCLALHCI	AP2A1	121	O95782
RNDMCHSLGLTCLEP	CD5	121	P06127
LNCGIMLRECIRHEP	CAB39	141	Q9Y376
SSTEPCGLRGCVMHV	DDIT4L	96	Q96D03
MASHVECRPLGVFEC	CDPF1	1	Q6NVV7
VTETLGMTHCCINPI	CCR5	281	P51681
ECVSQIVLHCSGMDP	DIAPH2	451	O60879
VCMECQGHGERISPK	DNAJA1	176	P31689
VRHPPDEDCTICMER	DTX4	401	Q9Y2E6
VRSVDNTMHCEEPIC	CASP8AP2	661	Q9UKL3
RCTENPMVRHECAEA	DOHH	231	Q9BU89
RPCETLGLSHLSGMC	ADAMTS12	356	P58397
MCQALSCHTDPLDQS	ADAMTS13	331	Q76LX8
ECHPSGCLIDLCLQM	ANO3	681	Q9BYT9
SFICRMRCGNAPLDH	ARNT2	236	Q9HBZ2
LMECTICNEIVHPGC	FBXL19	111	Q6PCT2
RVFQHLGPRELCICM	FBXL19	431	Q6PCT2
HNCDRPPSTGVMECR	DENND4A	1841	Q7Z401
DREVMCGATEPCILH	PCDHB5	91	Q9Y5E4
SLAQMESCRADCEGP	P3H3	246	Q8IVL6
QLRGSHTMLCTEDPC	DSG3	981	P32926
VSRPCLNGGTCHMLS	NOTCH2NLB	111	P0DPK3
VSRPCLNGGTCHMLS	NOTCH2	111	Q04721
SNPCIHGICMDGINR	NOTCH2	651	Q04721
CLHDGQTRPALDMCQ	C22orf46	176	C9J442
MEEALCTACCHLNPV	CDIPTOSP	46	P0DO92
SLTLNMPRCGHQEVD	OR2B3	161	O76000
RCHMSCSALLNPNLE	LYZL4	91	Q96KX0
LDCCPHDILAGTRMD	LUC7L	41	Q9NQ29
RIGDPQLVICMDCSA	AK5	476	Q9Y6K8
ECRMTPRHAGCDVTE	HHLA3	21	Q9XRX5
CSTERRHDPLTVMDG	HERC2	3646	O95714
LEGMCIQADCSRPQS	KIAA0319L	101	Q8IZA0
EHNCLGTELCVPMSR	LRP1	76	Q07954
LPCSDNCTALMVSHI	FRMD7	111	Q6ZUT3
VCGSPDLDMHALQRS	HECTD2	661	Q5U5R9
NHVMLSCCEGEEPLI	FBLN2	546	P98095
GQLPRALDVMACVDC	PER1	1191	O15534
CTLCPANLVLHMDDS	PCSK5	1686	Q92824
CPLHCEAVMSRGLCV	OR14K1	126	Q8NGZ2
CMDPGLSNCTIHIVT	NUDT5	131	Q9UKK9
GAHRCIVMVCEQPEV	NPEPL1	106	Q8NDH3
DREHSLSCHPMNGEC	PEAR1	366	Q5VY43
PCLICMNHRTNESIS	GAREM1	196	Q9H706
MRSHSGERPFVCLIC	ZFPM1	311	Q8IX07
TCVMCHRSLDGIPFT	LPP	501	Q93052
KGDGTTRCSCPMHLV	LRP6	1221	O75581
TRCSCPMHLVLLQDE	LRP6	1226	O75581
PMSERIQEVSCCLLH	LRRK2	261	Q5S007
ESEQGPCRRHMEASL	IGFBP5	186	P24593
KRCVMNVPSLCGTDH	PRKCB	141	P05771
EGVNLLCRSMRLPHC	NLRP5	966	P59047
VRVLCCETPRGCHMT	MUC5AC	1836	P98088
GSPAMEQHCSLRVDL	PCDHGC4	326	Q9Y5F7
ECCLEMHVRGLLEPL	PADI2	611	Q9Y2J8
CRAALPLMSVEDCGN	HECTD4	1431	Q9Y4D8
HRMLATGECTPEDLC	OSGEP	216	Q9NPF4
ACLALLPCCNRGHMV	ITGB4	741	P16144
CTHDRNTMEALPACL	TK1	66	P04183
AMGEVILAVCHPDCI	MACF1	6831	Q9UPN3
CTEGFVQRHMPTIRC	ACAN	2476	P16112
IGSENNMTSCHRPIC	RELN	2956	P78509
PMTLVFGCRCSQLDH	NOS3	1041	P29474
CGSIEPCVLHLQVLM	PCDHB11	96	Q9Y5F2
CSDVIMDHCSPQLTG	ZNF561-AS1	41	K7EIQ3
CAMRSFVAHCPELLT	HEATR5B	616	Q9P2D3
DCLECSHPVTQVRNM	GRHL3	581	Q8TE85
MECSICNEIIHPGCL	KDM2B	686	Q8NHM5
GNLPSAMRSHGCVCV	KLHL23	541	Q8NBE8
MCEDHDRILLAGCPS	GNE	171	Q9Y223
MVPVSGHENCCLTCD	BAMBI	216	Q13145
ICMDRHIAVVFIPCG	BIRC8	191	Q96P09
KGCLHMDPTQRLTCE	CDKL1	266	Q00532
ECTLPIAGRHRMDAC	FBN1	966	P35555
LVQERMCTEAPEVCH	COL6A5	986	A8TX70
HLMELNRSVCLECPE	FASTKD1	661	Q53R41
TLSPEHCRPLAGECM	CXXC4	31	Q9H2H0
LFLEGSLHPCNVLMC	DIP2C	901	Q9Y2E4
CESSCHMPTLLGAII	HTR1A	371	P08908
ESMRHISEGCPGVLC	FBXL13	261	Q8NEE6
CSDGRVLCDETMCHP	ECM2	126	O94769
NDRPMCRICHEGSSQ	MARCHF3	66	Q86UD3
LPMTRHCLTHICQDT	KANSL2	316	Q9H9L4
LKPCALSEIGCHMNI	KLKB1	191	P03952
ARCDRCLPGFHMLTD	LAMC2	111	Q13753
TAHLVNSSCPGLMCV	SLC44A4	411	Q53GD3
SHACNRICESMGLAP	EEF2K	311	O00418
LHECSPSQMDLLCAQ	FANCE	316	Q9HB96
RFLEGTLHPCNVLMC	DIP2A	916	Q14689
MLRTSTPNLCGGLHC	HHIPL2	1	Q6UWX4
IERCLGHLTPMQESC	SEC14L5	231	O43304
MSPGIIQQLLSCSCH	SLC39A12	336	Q504Y0
MAGCLEDCTRQAPES	POLRMT	171	O00411
VHCEAGISRSPTICM	DUSP5	261	Q16690
SRVTVCHLQAVPVCM	DSCR10	71	P59022
TDGLQEVPLCSCRME	EHMT1	511	Q9H9B1
PLHCAASCNDTVICM	PPP1R13L	696	Q8WUF5
HLSFPACRQSIMGLC	LINC00575	71	Q6W349
NGCLVPAMRLHATCL	CNTD1	196	Q8N815
MCGRTSCHLPRDVLT	HMCES	1	Q96FZ2
QDTEMGPCRRHLDSV	IGFBP6	156	P24592
GQSCETCGIRMHLPC	NSMCE1	201	Q8WV22
MTRAHEVPSVVQCCV	DNAH5	1666	Q8TE73
THCHCEPDGRMLLRV	LGR5	36	O75473
CLDTPLCNGHTTGMD	OGT	921	O15294
CCMVTEFILLGIPHT	OR10D3	6	Q8NH80
LNCCPHDVLSGTRMD	LUC7L2	41	Q9Y383
GTMVGLIAPCTCDAH	MROH2A	996	A6NES4
SLGIPDADCCRRHME	MAP4K1	326	Q92918
LCINMAHVSPLRCTE	METTL26	106	Q96S19
GTSHCCRPELEAETM	RUSC2	186	Q8N2Y8
ILCPASMEATEHCGR	USH2A	3401	O75445
MDSLTHAGQRPCDLA	PPP1R12C	286	Q9BZL4
HCSPLTCAQGEEMVL	SSPOP	5021	A2VEC9
SLCEAVRAGCAPLME	SFRP5	126	Q5T4F7
GKCEHSINMQEPSCR	TMEFF2	276	Q9UIK5
KQCVINVPSLCGMDH	PRKCA	141	P17252
DPRTLQRMACEVACG	AATK	226	Q6ZMQ8
HSIVDCVTMLCAPLG	SLC16A12	91	Q6ZSM3
NGPSARSCHKMCIDI	MKLN1	321	Q9UL63
CIEVDVLGMPLDSCH	PLCE1	1891	Q9P212
DSPIDCVLLECGHMV	RFFL	321	Q8WZ73
GLRCDECEPRHILME	LAMA1	1536	P25391
QVHCMDDVCGLLPFL	RHBDF1	631	Q96CC6
QPCFLGMESCGIHET	POTEJ	926	P0CG39
HRTCPLCMFNITEGD	RNF43	306	Q68DV7
CVITTDNALCREGPM	SOCS4	196	Q8WXH5
CEIHPSMILGVCASI	POLR2B	696	P30876
INPEHCMLVCGSRAG	SLC5A3	331	P53794
GACSDVSRAQMCPKH	MYCBP2	4576	O75592
VSFPCTRNGCVDMEH	PXYLP1	306	Q8TE99
TVQFSDMRTCHVCPL	HERC2P3	956	Q9BVR0
TGLLCHLEDMCLSQP	NOTCH4	386	Q99466
HTAMVGGDPRCCELL	SHANK1	286	Q9Y566
RMSLLARHEESGCCP	SNAI3	276	Q3KNW1
MGNILTCCVHPSVSL	AGAP5	1	A6NIR3
QLCHMLVEPNLCRSV	CDCA4	46	Q9BXL8
LEFCCHMLRGTIDPK	CLOCK	191	O15516
MRHCINCCIQLLPDG	CHST15	1	Q7LFX5
LSCQIPGLVKDCMEH	CLUH	751	O75153
LPHNRMQALTSCECT	RNF31	706	Q96EP0
DMCIHVCRLGCDRPV	TBL1X	391	O60907
VIQDITMELHCPLCN	TRIM69	31	Q86WT6
CGRPMEQSICIDCHA	RNF213	4516	Q63HN8
CPEDQLRCLSPMNHL	WFDC5	81	Q8TCV5
GPRCETMVCNRHCEN	VWDE	1386	Q8N2E2
MLELHGNPFECTCDI	TLR8	766	Q9NR97
MAPNASCLCVHVRSE	UBD	1	O15205
ATVEALRSGMCCPDL	TYRP1	31	P17643
QTGRCLCLFRSPMHV	WDR90	441	Q96KV7
TLMAELESHPCDICG	ZNF671	156	Q8TAW3
PVMTDCGHNFCRECI	TRIM11	26	Q96F44
SPCARTCQSLHINEM	VWF	306	P04275
ASVLLGHSPGCEMCS	NOD2	16	Q9HC29
MSVNTQPLCHECSER	TNFAIP3	396	P21580
ACRSEELCMECQHPN	TNFAIP3	726	P21580
HMETHSDNPLRCDIC	RREB1	226	Q92766
PLGEVLCCAISDMNT	STOX1	121	Q6ZVD7
PDLHNMVSLCRDDGT	SUSD4	156	Q5VX71
PIPERGDLSCRMHTC	EXT2	76	Q93063
RCFPDGLAHSDLMCT	PLPP5	121	Q8NEB5
MRHSGAKPLQCEVCG	ZNF276	516	Q8N554
MIDCLVSCFRISPHN	NF1	376	P21359
MPTKHLSDSVCAVCG	RNF121	216	Q9H920
ALRESCQAEHPMASC	TACC2	1176	O95359
EPHGEDLLCCCSSMV	RFPL2	131	O75678
VSPELVCSMLHLCSG	PSAP	376	P07602
PCTDNLDDICMHLTN	TTLL6	251	Q8N841
GRLCCSEHDPMAPVS	NSD3	1401	Q9BZ95
QPRLFECSSHMGCLV	VILL	611	O15195
GCCREDAMVASRLTP	ZKSCAN4	201	Q969J2
CDMCVPFLTDILHLT	ZNF416	106	Q9BWM5
IIPMRSRGPACCDHE	XP32	231	Q5T750
CRGPDEALLTCKHML	TTC7B	596	Q86TV6
VRCEMEGCGTVLAHP	ZFP91	311	Q96JP5
LPTCLQHRSCDACMS	PLXDC1	301	Q8IUK5
CMTNHVSSLPLEGCG	THSD4	821	Q6ZMP0
EPCGLMNHLTAVCEV	POLR1B	506	Q9H9Y6
DAIAPGISEHTCMRA	VSIG2	286	Q96IQ7
METVGSDIRSCPLCQ	TBKBP1	576	A7MCY6
LEISRCMGPNCTHQK	VWA3A	876	A6NCI4
PTVMTDKCHDCGAIL	UNC79	2001	Q9P2D8
SDESPEQCHMRTCRI	VLDLR	101	P98155
LSPLDNSKAVCIHCM	ZBED4	296	O75132
EMDSLLRPHTCPQCG	ZNF641	256	Q96N77
HPSCNLQDLELMGCV	NLRP14	926	Q86W24