Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionFMN binding

NOS1 NOS2 NOS3 TYW1B TYW1

2.97e-07161905GO:0010181
GeneOntologyMolecularFunctionnitric-oxide synthase activity

NOS1 NOS2 NOS3

8.48e-0731903GO:0004517
GeneOntologyMolecularFunctiontetrahydrobiopterin binding

NOS1 NOS2 NOS3

3.37e-0641903GO:0034617
GeneOntologyMolecularFunctionmetallopeptidase activity

ZMPSTE24 MMP27 PHEX BMP1 MMP24 MMP15 TRHDE NAALADL1 ANPEP TMPRSS6 IDE

3.53e-0620019011GO:0008237
GeneOntologyMolecularFunctiontransmembrane transporter activity

TTYH1 GABRG2 NAT1 NAT2 SCN11A KCNH7 SLC22A15 SLC24A3 CALHM3 ABCA7 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 SLC37A1 TPCN2 TMEM63C CLIC4 ATP13A2 SLC46A3 SLC9A5 SLC25A12 LRP6 GSDMA ANO7 ATP12A

7.22e-06118019028GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C CLIC4 ANO7

8.67e-0645919016GO:0005216
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 SLC37A1 TPCN2 TMEM63C CLIC4 SLC46A3 SLC9A5 SLC25A12 ANO7 ATP12A

1.18e-0575819021GO:0015318
GeneOntologyMolecularFunctionchannel activity

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C CLIC4 GSDMA ANO7

1.18e-0552519017GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C CLIC4 GSDMA ANO7

1.21e-0552619017GO:0022803
GeneOntologyMolecularFunctionomega peptidase activity

GGT1 GGTLC3 TRHDE GGT2P

1.32e-05161904GO:0008242
GeneOntologyMolecularFunctiontransporter activity

TTYH1 GABRG2 NAT1 NAT2 SCN11A KCNH7 SLC22A15 SLC24A3 CALHM3 ABCA7 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 SLC37A1 TPCN2 TMEM63C CLIC4 ATP13A2 ATP8B2 SLC46A3 SLC9A5 SLC25A12 LRP6 GSDMA ANO7 ATP12A

1.34e-05128919029GO:0005215
GeneOntologyMolecularFunctionpeptidase activity

HGFAC ZMPSTE24 MMP27 GGT1 PHEX BMP1 MMP24 JOSD2 GGTLC3 MMP15 VCPIP1 TRHDE NAALADL1 ANPEP TMPRSS6 SHH IDE GGT2P IHH

1.64e-0565419019GO:0008233
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ZMPSTE24 MMP27 PHEX BMP1 MMP24 MMP15 TMPRSS6 IDE

1.96e-051201908GO:0004222
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C CLIC4 ATP13A2 SLC46A3 SLC9A5 SLC25A12 ANO7 ATP12A

2.30e-0579319021GO:0015075
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGT1 GGTLC3 GGT2P

6.83e-0591903GO:0036374
GeneOntologyMolecularFunctionarginine binding

NOS1 NOS2 NOS3

6.83e-0591903GO:0034618
GeneOntologyMolecularFunctiontRNA-4-demethylwyosine synthase activity

TYW1B TYW1

9.01e-0521902GO:0102521
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TTYH1 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 SLC46A3 SLC9A5 ATP12A

1.53e-0446519014GO:0046873
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TTYH1 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C ATP13A2 SLC46A3 SLC9A5 SLC25A12 ATP12A

2.14e-0466419017GO:0008324
GeneOntologyMolecularFunctionarylamine N-acetyltransferase activity

NAT1 NAT2

2.69e-0431902GO:0004060
GeneOntologyMolecularFunctionapolipoprotein receptor activity

ABCA7 LRP1

2.69e-0431902GO:0030226
GeneOntologyMolecularFunctioncholesterol-protein transferase activity

SHH IHH

2.69e-0431902GO:0140853
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TTYH1 SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C SLC46A3 SLC9A5 SLC25A12 ATP12A

3.41e-0462719016GO:0022890
GeneOntologyMolecularFunctionglucosidase activity

KL MGAM GBA2

3.55e-04151903GO:0015926
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1B LRP1 LRP6

4.33e-04161903GO:0005041
GeneOntologyMolecularFunctionmonoatomic cation channel activity

SCN11A KCNH7 SLC24A3 CALHM3 TRPM3 PKD1 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C

4.64e-0434319011GO:0005261
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

TTYH1 GABRG2 KCNH7 SCNN1A KCNT1 TPCN2 TMEM63C ANO7

5.35e-041931908GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

TTYH1 GABRG2 KCNH7 SCNN1A KCNT1 TPCN2 TMEM63C ANO7

6.12e-041971908GO:0022834
GeneOntologyMolecularFunctionadenylate cyclase activity

ADCY10 ADCY9 ADCY4

6.23e-04181903GO:0004016
GeneOntologyMolecularFunctionaminopeptidase activity

MMP15 TRHDE NAALADL1 ANPEP

7.33e-04431904GO:0004177
GeneOntologyMolecularFunctionthreonine-type peptidase activity

GGT1 GGTLC3 GGT2P

8.58e-04201903GO:0070003
GeneOntologyMolecularFunctionlyase activity

ADCY10 ADCY9 TSEN34 ADCY4 CRY1 RSAD2 TYW1B TYW1

9.87e-042121908GO:0016829
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1B LRP1 LRP6

9.94e-04211903GO:0030228
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SCN11A SLC24A3 SCNN1A CACNA1H TPCN2 SLC9A5 ATP12A

1.28e-031711907GO:0015081
GeneOntologyMolecularFunctioncargo receptor activity

LRP1B ABCA7 TFR2 LRP1 LRP6

1.31e-03851905GO:0038024
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGT1 GGT2P

1.32e-0361902GO:0000048
GeneOntologyMolecularFunctionbeta-glucosidase activity

KL GBA2

1.32e-0361902GO:0008422
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGT1 GGT2P

1.32e-0361902GO:0002951
GeneOntologyMolecularFunctionchloride channel activity

TTYH1 GABRG2 CLIC2 CLIC4 ANO7

1.38e-03861905GO:0005254
GeneOntologyMolecularFunctiongated channel activity

TTYH1 GABRG2 KCNH7 CALHM3 SCNN1A CACNA1H KCNT1 TPCN2 TMEM63C ANO7

1.40e-0333419010GO:0022836
GeneOntologyMolecularFunctioncyclase activity

ADCY10 ADCY9 ADCY4

1.48e-03241903GO:0009975
GeneOntologyMolecularFunctioncalcium channel activity

SLC24A3 CALHM3 TRPM3 PKD1 CACNA1H TPCN2

1.48e-031291906GO:0005262
GeneOntologyMolecularFunctionsodium channel activity

SCN11A SCNN1A CACNA1H TPCN2

1.51e-03521904GO:0005272
GeneOntologyMolecularFunctionphosphorus-oxygen lyase activity

ADCY10 ADCY9 ADCY4

1.67e-03251903GO:0016849
GeneOntologyMolecularFunctionoxo-acid-lyase activity

TYW1B TYW1

1.83e-0371902GO:0016833
GeneOntologyMolecularFunctionmetalloaminopeptidase activity

MMP15 TRHDE ANPEP

1.88e-03261903GO:0070006
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN11A CACNA1H TPCN2

1.88e-03261903GO:0005248
GeneOntologyMolecularFunctiontransition metal ion binding

ADCY10 AOC1 MMP27 F8 HEPH PHEX BMP1 MMP24 SCAPER MMP15 NOS1 NOS3 ALOX15 TRHDE P4HA2 NAALADL1 ANPEP FA2H SHH IDE TRIM68 ATP13A2

2.16e-03118919022GO:0046914
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGT1 GGT2P

2.43e-0381902GO:0103068
GeneOntologyMolecularFunctionpatched binding

SHH IHH

2.43e-0381902GO:0005113
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ABCA7 ATP8B2

2.43e-0381902GO:0090554
GeneOntologyMolecularFunctioncatalytic activity, acting on a tRNA

GGT1 TSEN34 GGT2P NARS2 TYW1B TYW1

2.58e-031441906GO:0140101
GeneOntologyMolecularFunctionhydrolase activity, hydrolyzing O-glycosyl compounds

KL KLB MGAM HEXD GBA2

3.05e-031031905GO:0004553
GeneOntologyMolecularFunctionmonoatomic anion channel activity

TTYH1 GABRG2 CLIC2 CLIC4 ANO7

3.05e-031031905GO:0005253
GeneOntologyMolecularFunctionphosphatidylinositol-3,5-bisphosphate binding

RS1 TPCN2 ATP13A2

3.13e-03311903GO:0080025
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

SLC24A3 CALHM3 TRPM3 PKD1 CACNA1H TPCN2

3.27e-031511906GO:0015085
GeneOntologyMolecularFunctionexopeptidase activity

ZMPSTE24 MMP15 TRHDE NAALADL1 ANPEP

4.05e-031101905GO:0008238
GeneOntologyBiologicalProcessmonoatomic ion transport

TTYH1 GABRG2 SCN11A KCNH7 ZMPSTE24 SLC22A15 SLC24A3 CALHM3 NKAIN2 HEPH NEDD4 TRPM3 CLIC2 PKD1 SCNN1A ARC CACNA1H NOS1 NOS3 KCNT1 GP1BA TPCN2 WWP1 TMEM63C CLIC4 ATP13A2 ATP8B2 TFR2 SPTBN4 SLC46A3 SLC9A5 SLC25A12 ANO7 ATP12A

1.70e-07137419334GO:0006811
GeneOntologyBiologicalProcesspositive regulation of purine nucleotide biosynthetic process

ADCY10 NOS1 NOS2 NOS3 SLC25A12

3.11e-06251935GO:1900373
GeneOntologyBiologicalProcesspositive regulation of nucleotide biosynthetic process

ADCY10 NOS1 NOS2 NOS3 SLC25A12

3.11e-06251935GO:0030810
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 NEDD4 TRPM3 CLIC2 PKD1 SCNN1A ARC CACNA1H NOS1 KCNT1 GP1BA TPCN2 WWP1 TMEM63C CLIC4 ATP13A2 ATP8B2 SLC46A3 SLC9A5 SLC25A12 ANO7 ATP12A

5.56e-06111519327GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transport

TTYH1 SCN11A KCNH7 ZMPSTE24 SLC24A3 CALHM3 NKAIN2 HEPH NEDD4 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H NOS1 NOS3 KCNT1 GP1BA TPCN2 TMEM63C ATP13A2 TFR2 SPTBN4 SLC46A3 SLC9A5 SLC25A12 ATP12A

1.09e-05115719327GO:0006812
GeneOntologyBiologicalProcesssodium ion transport

SCN11A SLC24A3 NKAIN2 NEDD4 SCNN1A CACNA1H NOS1 NOS3 TPCN2 SPTBN4 SLC9A5 ATP12A

1.15e-0527519312GO:0006814
GeneOntologyBiologicalProcesspositive regulation of guanylate cyclase activity

NOS1 NOS2 NOS3

1.58e-0561933GO:0031284
GeneOntologyBiologicalProcesscellular catabolic process

ADCY10 TSPAN15 ZMPSTE24 VPS13C ABCA7 GGT1 NEDD4 PIK3R4 GGTLC3 AP5Z1 PLA2G5 NOS1 NOS2 NOS3 TRHDE VPS18 NAALADL1 TPCN2 ANPEP IDE TRIM68 IDS ATP13A2 GBA2 GGT2P MAPK15 LPIN2 LRP1

1.63e-05125319328GO:0044248
GeneOntologyBiologicalProcessmetal ion transport

TTYH1 SCN11A KCNH7 ZMPSTE24 SLC24A3 CALHM3 NKAIN2 HEPH NEDD4 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H NOS1 NOS3 KCNT1 GP1BA TPCN2 TFR2 SPTBN4 SLC46A3 SLC9A5 ATP12A

2.24e-05100019324GO:0030001
GeneOntologyBiologicalProcessregulation of purine nucleotide biosynthetic process

ADCY10 NOS1 NOS2 NOS3 SLC25A12

3.43e-05401935GO:1900371
GeneOntologyBiologicalProcessregulation of nucleotide biosynthetic process

ADCY10 NOS1 NOS2 NOS3 SLC25A12

3.43e-05401935GO:0030808
GeneOntologyBiologicalProcessamyloid-beta clearance by cellular catabolic process

ABCA7 IDE LRP1

4.36e-0581933GO:0150094
GeneOntologyBiologicalProcessregulation of guanylate cyclase activity

NOS1 NOS2 NOS3

4.36e-0581933GO:0031282
GeneOntologyBiologicalProcessleukotriene biosynthetic process

GGT1 GGTLC3 PLA2G5 GGT2P

4.76e-05221934GO:0019370
GeneOntologyBiologicalProcesspeptide catabolic process

TRHDE NAALADL1 ANPEP IDE

5.72e-05231934GO:0043171
GeneOntologyBiologicalProcesscell surface receptor signaling pathway involved in heart development

MKS1 VANGL2 LRP6

6.50e-0591933GO:0061311
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TTYH1 GABRG2 SCN11A KCNH7 SLC24A3 CALHM3 NEDD4 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H NOS1 KCNT1 GP1BA SLC37A1 TPCN2 CLIC4 SLC46A3 SLC9A5 SLC25A12 ANO7 ATP12A

8.30e-05101719323GO:0098660
GeneOntologyBiologicalProcessnegative regulation of developmental pigmentation

TPCN2 IHH

8.71e-0521932GO:0048086
GeneOntologyBiologicalProcessarginine catabolic process

NOS1 NOS2 NOS3

9.22e-05101933GO:0006527
GeneOntologyBiologicalProcessleukotriene D4 biosynthetic process

GGT1 GGTLC3 GGT2P

9.22e-05101933GO:1901750
GeneOntologyBiologicalProcesspostsynaptic neurotransmitter receptor internalization

NEDD4 AP2A1 AP2A2 ARC LRP1

1.13e-04511935GO:0098884
GeneOntologyBiologicalProcesspostsynaptic endocytosis

NEDD4 AP2A1 AP2A2 ARC LRP1

1.13e-04511935GO:0140239
GeneOntologyBiologicalProcessprotein catabolic process

TSPAN15 ZMPSTE24 DCST1 NEDD4 AP5Z1 FBXW5 PKD1 SGSM3 ASCC3 NOS2 SMURF2 TMUB2 FBXO48 KBTBD6 WWP1 SHH IDE IDS ATP13A2 KLHDC1 MAPK15 LRP1 CCAR1 NGLY1

1.23e-04111519324GO:0030163
GeneOntologyBiologicalProcessglutathione catabolic process

GGT1 GGTLC3 GGT2P

1.26e-04111933GO:0006751
GeneOntologyBiologicalProcesscAMP biosynthetic process

ADCY10 ADCY9 ADCY4

1.26e-04111933GO:0006171
GeneOntologyBiologicalProcesspeptide metabolic process

GGT1 TRHDE NAALADL1 ANPEP IDE GGT2P

1.38e-04841936GO:0006518
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SCN11A SLC24A3 NEDD4 SCNN1A CACNA1H NOS1 TPCN2 SLC9A5 ATP12A

1.55e-042081939GO:0035725
GeneOntologyBiologicalProcesspositive regulation of nucleotide metabolic process

ADCY10 NOS1 NOS2 NOS3 SLC25A12

1.62e-04551935GO:0045981
GeneOntologyBiologicalProcesspositive regulation of purine nucleotide metabolic process

ADCY10 NOS1 NOS2 NOS3 SLC25A12

1.62e-04551935GO:1900544
GeneOntologyBiologicalProcessWnt signaling pathway, planar cell polarity pathway

MKS1 PTK7 SMURF2 VANGL2 LRP6

1.62e-04551935GO:0060071
GeneOntologyBiologicalProcessleukotriene D4 metabolic process

GGT1 GGTLC3 GGT2P

1.67e-04121933GO:1901748
GeneOntologyBiologicalProcessneurotransmitter receptor internalization

NEDD4 AP2A1 AP2A2 ARC LRP1

2.09e-04581935GO:0099590
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TTYH1 SCN11A KCNH7 SLC24A3 CALHM3 NEDD4 TRPM3 CLIC2 PKD1 SCNN1A CACNA1H NOS1 KCNT1 GP1BA TPCN2 TMEM63C ATP13A2 SLC46A3 SLC9A5 SLC25A12 ATP12A

2.09e-0494219321GO:0098655
GeneOntologyBiologicalProcessnegative regulation of T cell differentiation in thymus

SHH NFKBID IHH

2.15e-04131933GO:0033085
GeneOntologyBiologicalProcessregulation of engulfment of apoptotic cell

ABCA7 ALOX15

2.60e-0431932GO:1901074
GeneOntologyBiologicalProcessprotein splicing

SHH IHH

2.60e-0431932GO:0030908
GeneOntologyBiologicalProcessnon-canonical Wnt signaling pathway involved in heart development

VANGL2 LRP6

2.60e-0431932GO:0061341
GeneOntologyBiologicalProcessintein-mediated protein splicing

SHH IHH

2.60e-0431932GO:0016539
GeneOntologyBiologicalProcesssebaceous gland cell differentiation

FA2H GSDMA

2.60e-0431932GO:0001949
GeneOntologyBiologicalProcessself proteolysis

TMPRSS6 SHH IHH

3.38e-04151933GO:0097264
GeneOntologyBiologicalProcessregulation of establishment of planar polarity involved in neural tube closure

PTK7 VANGL2 LRP6

3.38e-04151933GO:0090178
GeneOntologyBiologicalProcessmembrane organization

ZMPSTE24 NFASC DCST1 ABCA7 PLA2G5 ALOX15 VCPIP1 DOCK2 VPS18 PDCD6 FA2H MTFP1 ATP13A2 GBA2 ATP8B2 CRB1 SPTBN4 MAPK15 SYNGR2 ANO7

3.78e-0491419320GO:0061024
GeneOntologyBiologicalProcessestablishment of planar polarity involved in neural tube closure

PTK7 VANGL2 LRP6

4.13e-04161933GO:0090177
GeneOntologyBiologicalProcessaxis elongation

PTK7 SHH VANGL2 LRP6

4.28e-04381934GO:0003401
GeneOntologyBiologicalProcessWnt signaling pathway involved in heart development

VANGL2 LRP6

5.16e-0441932GO:0003306
GeneOntologyBiologicalProcessleukotriene metabolic process

GGT1 GGTLC3 PLA2G5 GGT2P

5.74e-04411934GO:0006691
GeneOntologyBiologicalProcessestablishment of planar polarity of embryonic epithelium

PTK7 VANGL2 LRP6

5.93e-04181933GO:0042249
GeneOntologyBiologicalProcessgenitalia morphogenesis

NEUROG1 SHH LRP6

5.93e-04181933GO:0035112
GeneOntologyBiologicalProcessheart looping

ARL13B SHH VANGL2 LRP6 IHH

6.11e-04731935GO:0001947
GeneOntologyBiologicalProcessestablishment of epithelial cell polarity

PTK7 PKD1 SHH VANGL2

6.30e-04421934GO:0090162
GeneOntologyCellularComponentcytoplasmic vesicle membrane

TSPAN15 GABRG2 ZMPSTE24 VPS13C HLA-H NFASC DCST1 ABCA7 PIK3R4 AP2A1 AP2A2 PKD1 ARC NOS3 ENTPD7 KDELR3 MGAM VPS18 TPCN2 PDCD6 ANPEP CLIC4 ATP13A2 SLC9A5 SYNGR2 TLR3 LRP1 LRP6

2.04e-05130719028GO:0030659
GeneOntologyCellularComponentvesicle membrane

TSPAN15 GABRG2 ZMPSTE24 VPS13C HLA-H NFASC DCST1 ABCA7 PIK3R4 AP2A1 AP2A2 PKD1 ARC NOS3 ENTPD7 KDELR3 MGAM VPS18 TPCN2 PDCD6 ANPEP CLIC4 ATP13A2 SLC9A5 SYNGR2 TLR3 LRP1 LRP6

2.61e-05132519028GO:0012506
GeneOntologyCellularComponentendolysosome membrane

AP2A1 AP2A2 TPCN2 TLR3

2.86e-05201904GO:0036020
GeneOntologyCellularComponentmembrane protein complex

TTYH1 TRAV10 GABRG2 SCN11A KCNH7 HLA-H PIK3R4 AP2A1 AP2A2 CLIC2 AP5Z1 PKD1 SCNN1A CACNA1H GP1BA VPS18 TPCN2 PDCD6 CLIC4 CRB1 TFR2 SYNE3 SKAP1 LRP1 LRP6 ATP12A CATSPERG CDH15 TRAV20 TRAV16

3.57e-05149819030GO:0098796
GeneOntologyCellularComponentendolysosome

AP2A1 AP2A2 TPCN2 TLR3

1.51e-04301904GO:0036019
GeneOntologyCellularComponentapical part of cell

ADCY10 MYO7B ABCA7 KL AP2A1 ASPM SCNN1A NOS3 MGAM NAALADL1 CLIC4 CRB1 VANGL2 LRP1 ATP12A

3.50e-0459219015GO:0045177
GeneOntologyCellularComponentendosome

TSPAN15 ZMPSTE24 VPS13C HLA-H ABCA7 PIK3R4 DENND10 AP2A1 AP2A2 AP5Z1 RABGAP1L ARC PLA2G5 VPS18 TPCN2 PDCD6 IDE ATP13A2 SLC9A5 TLR3 RASGEF1B LRP1 LRP6

3.97e-04116719023GO:0005768
GeneOntologyCellularComponentapical cytoplasm

MYO7B VANGL2

4.87e-0441902GO:0090651
GeneOntologyCellularComponentmeiotic spindle

ASPM SHCBP1L MAPK15

6.43e-04191903GO:0072687
GeneOntologyCellularComponentmonoatomic ion channel complex

TTYH1 GABRG2 SCN11A KCNH7 CLIC2 PKD1 SCNN1A CACNA1H TPCN2 CLIC4 CATSPERG

7.12e-0437819011GO:0034702
GeneOntologyCellularComponentsomatodendritic compartment

ADCY10 GABRG2 SCN11A NFASC ADCY9 PTK7 NEDD4 NEUROG1 ARC MCRS1 CACNA1H NOS1 ADCY4 HTR1E SHH MAGEE1 ATP13A2 SYAP1 SPTBN4 SLC9A5 BRINP2 LRP1 LRP6

8.00e-04122819023GO:0036477
GeneOntologyCellularComponentplasma membrane protein complex

TRAV10 SCN11A HLA-H AP2A1 AP2A2 CACNA1H GP1BA CRB1 TFR2 SKAP1 LRP1 LRP6 ATP12A CATSPERG CDH15 TRAV20 TRAV16

8.51e-0478519017GO:0098797
GeneOntologyCellularComponentglial cell projection

ADCY10 NFASC ABCA7 CRB1

8.69e-04471904GO:0097386
GeneOntologyCellularComponentperinuclear region of cytoplasm

ADCY10 HEPH GGT1 NEDD4 PHEX PLA2G5 NOS1 NOS2 PDCD6 CLIC4 TRIM68 MAGEE1 SYAP1 GGT2P RAD50 LRP1 CCAR1 GSDMA FIGNL1

8.94e-0493419019GO:0048471
GeneOntologyCellularComponentmicrovillus

MYO7B STARD10 NFASC NEDD4 CLIC4 CRB1

9.18e-041231906GO:0005902
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

AP2A1 AP2A2 AP5Z1 VPS18

9.41e-04481904GO:0030119
GeneOntologyCellularComponentendosome membrane

TSPAN15 ZMPSTE24 VPS13C HLA-H ABCA7 AP2A1 AP2A2 ARC VPS18 TPCN2 ATP13A2 SLC9A5 TLR3 LRP6

1.26e-0360219014GO:0010008
GeneOntologyCellularComponentlate endosome

TSPAN15 ZMPSTE24 VPS13C PIK3R4 DENND10 AP5Z1 VPS18 TPCN2 ATP13A2 RASGEF1B

1.36e-0334819010GO:0005770
GeneOntologyCellularComponenttransporter complex

TTYH1 GABRG2 SCN11A KCNH7 CLIC2 PKD1 SCNN1A CACNA1H TPCN2 CLIC4 ATP8B2 ATP12A CATSPERG

1.62e-0355019013GO:1990351
GeneOntologyCellularComponentcoated vesicle

HLA-H F8 AP2A1 AP2A2 ARC KDELR3 VPS18 PDCD6 VANGL2 LRP1

1.75e-0336019010GO:0030135
GeneOntologyCellularComponentchloride channel complex

TTYH1 GABRG2 CLIC2 CLIC4

1.79e-03571904GO:0034707
GeneOntologyCellularComponentmembrane raft

HLA-H ARC CACNA1H NOS1 NOS3 SMURF2 SHH SKAP1 LRP6 CDH15

1.82e-0336219010GO:0045121
GeneOntologyCellularComponentmembrane microdomain

HLA-H ARC CACNA1H NOS1 NOS3 SMURF2 SHH SKAP1 LRP6 CDH15

1.89e-0336419010GO:0098857
GeneOntologyCellularComponentdendrite

ADCY10 GABRG2 NFASC ADCY9 NEDD4 ARC MCRS1 CACNA1H NOS1 ADCY4 HTR1E SHH MAGEE1 SYAP1 SLC9A5 BRINP2 LRP1

2.20e-0385819017GO:0030425
GeneOntologyCellularComponentdendritic tree

ADCY10 GABRG2 NFASC ADCY9 NEDD4 ARC MCRS1 CACNA1H NOS1 ADCY4 HTR1E SHH MAGEE1 SYAP1 SLC9A5 BRINP2 LRP1

2.25e-0386019017GO:0097447
GeneOntologyCellularComponentsodium channel complex

SCN11A SCNN1A CACNA1H

2.27e-03291903GO:0034706
GeneOntologyCellularComponentplasma membrane raft

CACNA1H NOS1 NOS3 SKAP1 LRP6 CDH15

2.28e-031471906GO:0044853
GeneOntologyCellularComponentcoated membrane

AP2A1 AP2A2 AP5Z1 VPS18 PDCD6

2.84e-031061905GO:0048475
GeneOntologyCellularComponentmembrane coat

AP2A1 AP2A2 AP5Z1 VPS18 PDCD6

2.84e-031061905GO:0030117
GeneOntologyCellularComponentcell-cell junction

DCHS2 AOC1 STARD10 NFASC PTK7 SGSM3 CLIC4 CRB1 VANGL2 SPTBN4 MAPK15 SKAP1 CDH15

3.02e-0359119013GO:0005911
GeneOntologyCellularComponenttransmembrane transporter complex

TTYH1 GABRG2 SCN11A KCNH7 CLIC2 PKD1 SCNN1A CACNA1H TPCN2 CLIC4 ATP12A CATSPERG

3.09e-0352319012GO:1902495
GeneOntologyCellularComponentendocytic vesicle membrane

HLA-H PIK3R4 AP2A1 AP2A2 NOS3 ENTPD7 LRP1

3.32e-032121907GO:0030666
GeneOntologyCellularComponentlysosomal membrane

VPS13C HLA-H AP2A1 AP2A2 VPS18 TPCN2 ANPEP ATP13A2 SLC46A3 TLR3 LRP1

3.45e-0346219011GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

VPS13C HLA-H AP2A1 AP2A2 VPS18 TPCN2 ANPEP ATP13A2 SLC46A3 TLR3 LRP1

3.45e-0346219011GO:0098852
GeneOntologyCellularComponentcaveola

CACNA1H NOS1 NOS3 LRP6 CDH15

3.47e-031111905GO:0005901
GeneOntologyCellularComponentGolgi transport complex

COG6 TMEM115

3.52e-03101902GO:0017119
HumanPhenoUrinary incontinence

GABRG2 BNC2 VPS13C GGT1 AP5Z1 CACNA1H KCNT1 FA2H ATP13A2 GBA2 JMJD1C

1.75e-051746911HP:0000020
HumanPhenoUrinary or fecal incontinence

GABRG2 BNC2 VPS13C GGT1 AP5Z1 CACNA1H KCNT1 FA2H ATP13A2 GBA2 JMJD1C

1.75e-051746911HP:0007147
HumanPhenoImpaired continence

GABRG2 BNC2 VPS13C GGT1 AP5Z1 CACNA1H KCNT1 FA2H ATP13A2 GBA2 JMJD1C

1.85e-051756911HP:0031064
HumanPhenoImpairment of activities of daily living

GABRG2 BNC2 VPS13C GGT1 AP5Z1 CACNA1H KCNT1 FA2H ATP13A2 GBA2 JMJD1C

3.62e-051886911HP:0031058
MousePhenoabnormal neurocranium morphology

BNC2 ZMPSTE24 SPEF2 ADCY9 MKS1 NEDD4 PHEX BMP1 KL PKD1 SHH IDS LRP6

1.15e-0526915813MP:0000074
MousePhenoabnormal skeleton development

BNC2 GGT1 MKS1 PHEX KL PKD1 CACNA1H NOS1 NOS2 NOS3 WWP1 SHH GGT2P VANGL2 GPR68 LRP6 IHH

1.23e-0544715817MP:0002113
MousePhenoabnormal frontal bone morphology

BNC2 MKS1 NEDD4 PHEX BMP1 SHH LRP6

2.56e-05771587MP:0000107
MousePhenoabnormal lung lobe morphology

ADCY9 MKS1 PTK7 SHH VANGL2

3.18e-05331585MP:0010975
MousePhenoabnormal penile erection

GGT1 NOS3 GGT2P SPTBN4

4.25e-05181584MP:0001379
MousePhenoabnormal copulation physiology

GGT1 NOS3 GGT2P SPTBN4

5.33e-05191584MP:0031627
MousePhenoabnormal floor plate morphology

MKS1 PTK7 ARL13B SHH VANGL2

8.28e-05401585MP:0000925
MousePhenosmall vertebrae

GGT1 NEDD4 PHEX GGT2P

9.81e-05221584MP:0004610
MousePhenoabnormal cerebral blood flow rate

NOS1 NOS3

1.27e-0421582MP:0031182
MousePhenoabnormal orientation of outer hair cell stereociliary bundles

MKS1 PTK7 VANGL2 LRP6

1.40e-04241584MP:0004491
DomainFlavodoxin/NO_synth

NOS1 NOS2 NOS3 TYW1B TYW1

5.35e-0981885IPR008254
DomainFlavdoxin-like

NOS1 NOS2 NOS3 TYW1B TYW1

5.35e-0981885IPR001094
DomainFLAVODOXIN_LIKE

NOS1 NOS2 NOS3 TYW1B TYW1

5.35e-0981885PS50902
DomainFlavodoxin_1

NOS1 NOS2 NOS3 TYW1B TYW1

5.35e-0981885PF00258
Domain-

NOS1 NOS2 NOS3 TYW1B TYW1

2.37e-081018853.40.50.360
DomainFlavoprotein-like_dom

NOS1 NOS2 NOS3 TYW1B TYW1

2.37e-08101885IPR029039
DomainNO_synthase

NOS1 NOS2 NOS3

1.00e-0631883PF02898
DomainNOS_euk

NOS1 NOS2 NOS3

1.00e-0631883IPR012144
Domain-

NOS1 NOS2 NOS3

1.00e-06318833.90.340.10
DomainNOS_N

NOS1 NOS2 NOS3

1.00e-0631883IPR004030
DomainNOS

NOS1 NOS2 NOS3

1.00e-0631883PS60001
DomainZINC_PROTEASE

ZMPSTE24 MMP27 PHEX BMP1 MMP24 MMP15 TRHDE ANPEP

6.60e-06981888PS00142
DomainFAD_binding_1

NOS1 NOS2 NOS3

1.96e-0561883PF00667
Domain-

NOS1 NOS2 NOS3

1.96e-05618831.20.990.10
DomainFAD-binding_1

NOS1 NOS2 NOS3

1.96e-0561883IPR003097
DomainNADPH_Cyt_P450_Rdtase_dom3

NOS1 NOS2 NOS3

1.96e-0561883IPR023173
DomainrSAM

RSAD2 TYW1B TYW1

8.06e-0591883IPR007197
DomainRadical_SAM

RSAD2 TYW1B TYW1

8.06e-0591883PF04055
DomainINTEIN_N_TER

SHH IHH

1.01e-0421882PS50817
DomainArylamine_N-AcTrfase

NAT1 NAT2

1.01e-0421882IPR001447
Domain-

AP2A1 AP2A2

1.01e-04218822.60.40.1030
DomainClathrin_a-adaptin_app_Ig-like

AP2A1 AP2A2

1.01e-0421882IPR013038
DomainDUF5050

LRP1B LRP1

1.01e-0421882IPR032485
DomaintRNA_wybutosine-synth

TYW1B TYW1

1.01e-0421882IPR013917
DomainIntein_N

SHH IHH

1.01e-0421882IPR006141
DomainAcetyltransf_2

NAT1 NAT2

1.01e-0421882PF00797
DomainAP2_complex_asu

AP2A1 AP2A2

1.01e-0421882IPR017104
DomainClathrin_a-adaptin_app_sub_C

AP2A1 AP2A2

1.01e-0421882IPR003164
DomainDUF5050

LRP1B LRP1

1.01e-0421882PF16472
DomainWyosine_form

TYW1B TYW1

1.01e-0421882PF08608
DomainAlpha_adaptin_C

AP2A1 AP2A2

1.01e-0421882PF02296
DomainFlavoprot_Pyr_Nucl_cyt_Rdtase

NOS1 NOS2 NOS3

1.14e-04101883IPR001709
DomainLDLRA_1

LRP1B PKD1 TMPRSS6 LRP1 LRP6

1.18e-04481885PS01209
DomainLDLRA_2

LRP1B PKD1 TMPRSS6 LRP1 LRP6

1.30e-04491885PS50068
DomainPeptidase_Metallo

MMP27 BMP1 MMP24 MMP15

1.94e-04291884IPR006026
DomainZnMc

MMP27 BMP1 MMP24 MMP15

1.94e-04291884SM00235
DomainOxRdtase_FAD/NAD-bd

NOS1 NOS2 NOS3

2.07e-04121883IPR001433
DomainNAD_binding_1

NOS1 NOS2 NOS3

2.07e-04121883PF00175
DomainQuinoprot_gluc/sorb_DH

FBXW5 HHIPL2 LRP1

2.07e-04121883IPR011041
DomainHedgehog_signalling_dom

SHH IHH

3.00e-0431882IPR000320
DomainHintN

SHH IHH

3.00e-0431882SM00306
DomainHintC

SHH IHH

3.00e-0431882SM00305
DomainHedgehog

SHH IHH

3.00e-0431882IPR001657
DomainCu-oxidase

F8 HEPH

3.00e-0431882PF00394
DomainHH_signal

SHH IHH

3.00e-0431882PF01085
DomainHint

SHH IHH

3.00e-0431882PF01079
DomainHedgehog_sig/DD-Pept_Zn-bd_dom

SHH IHH

3.00e-0431882IPR009045
DomainHint_dom

SHH IHH

3.00e-0431882IPR001767
Domain-

SHH IHH

3.00e-04318823.30.1380.10
DomainHint_dom_N

SHH IHH

3.00e-0431882IPR003587
DomainHint_dom_C

SHH IHH

3.00e-0431882IPR003586
DomainCu-oxidase

F8 HEPH

3.00e-0431882IPR001117
DomainLdl_recept_b

LRP1B LRP1 LRP6

3.37e-04141883PF00058
DomainLDLRB

LRP1B LRP1 LRP6

3.37e-04141883PS51120
DomainLY

LRP1B LRP1 LRP6

4.18e-04151883SM00135
DomainLDLR_classB_rpt

LRP1B LRP1 LRP6

4.18e-04151883IPR000033
DomainCu-oxidase_2

F8 HEPH

5.97e-0441882IPR011706
DomainHedgehog/Intein_dom

SHH IHH

5.97e-0441882IPR028992
DomainClathrin_a/coatomer_app_sub_C

AP2A1 AP2A2

5.97e-0441882IPR015873
DomainDUF3377

MMP24 MMP15

5.97e-0441882PF11857
Domain-

SHH IHH

5.97e-04418822.170.16.10
DomainPept_M10A_metallopeptidase_C

MMP24 MMP15

5.97e-0441882IPR021805
Domain-

AP2A1 AP2A2

5.97e-04418823.30.310.30
DomainCu-oxidase_2

F8 HEPH

5.97e-0441882PF07731
DomainHemopexin_CS

MMP27 MMP24 MMP15

6.15e-04171883IPR018486
Domain-

LRP1B HHIPL2 LRP1 LRP6

6.21e-043918842.120.10.30
DomainPept_M10A_stromelysin-type

MMP27 MMP24 MMP15

7.33e-04181883IPR016293
Domain-

ADCY10 ADCY9 ADCY4

7.33e-041818833.30.70.1230
DomainNucleotide_cyclase

ADCY10 ADCY9 ADCY4

7.33e-04181883IPR029787
DomainGuanylate_cyc

ADCY10 ADCY9 ADCY4

8.64e-04191883PF00211
DomainGUANYLATE_CYCLASE_2

ADCY10 ADCY9 ADCY4

8.64e-04191883PS50125
DomainA/G_cyclase

ADCY10 ADCY9 ADCY4

8.64e-04191883IPR001054
DomainFd_Rdtase_FAD-bd

NOS1 NOS2 NOS3

8.64e-04191883IPR017927
DomainGUANYLATE_CYCLASE_1

ADCY10 ADCY9 ADCY4

8.64e-04191883PS00452
DomainFAD_FR

NOS1 NOS2 NOS3

8.64e-04191883PS51384
DomainCYCc

ADCY10 ADCY9 ADCY4

8.64e-04191883SM00044
DomainRiboflavin_synthase-like_b-brl

NOS1 NOS2 NOS3

8.64e-04191883IPR017938
DomainGLYCOSYL_HYDROL_F1_1

KL KLB

9.88e-0451882PS00572
DomainGlyco_hydro_1

KL KLB

9.88e-0451882PF00232
DomainCu-oxidase_3

F8 HEPH

9.88e-0451882IPR011707
DomainMULTICOPPER_OXIDASE1

F8 HEPH

9.88e-0451882PS00079
DomainGLYCOSYL_HYDROL_F1_2

KL KLB

9.88e-0451882PS00653
DomainCu_oxidase_CS

F8 HEPH

9.88e-0451882IPR033138
DomainGlyco_hydro_1

KL KLB

9.88e-0451882IPR001360
DomainCu-oxidase_3

F8 HEPH

9.88e-0451882PF07732
DomainPG_binding_1

MMP27 MMP24 MMP15

1.01e-03201883PF01471
DomainPeptidoglycan-bd-like

MMP27 MMP24 MMP15

1.01e-03201883IPR002477
DomainLdl_recept_a

LRP1B TMPRSS6 LRP1 LRP6

1.07e-03451884PF00057
Domain6-blade_b-propeller_TolB-like

LRP1B HHIPL2 LRP1 LRP6

1.17e-03461884IPR011042
Domain-

LRP1B TMPRSS6 LRP1 LRP6

1.17e-034618844.10.400.10
Domain-

MMP27 PHEX BMP1 MMP24 MMP15

1.35e-038118853.40.390.10
DomainMetalloPept_cat_dom

MMP27 PHEX BMP1 MMP24 MMP15

1.35e-03811885IPR024079
DomainCLIC

CLIC2 CLIC4

1.47e-0361882IPR002946
DomainCu_oxidase_Cu_BS

F8 HEPH

1.47e-0361882IPR002355
DomainTFR_dimer

NAALADL1 TFR2

1.47e-0361882PF04253
Domain-

NAALADL1 TFR2

1.47e-03618821.20.930.40
DomainLDrepeatLR_classA_rpt

LRP1B TMPRSS6 LRP1 LRP6

1.48e-03491884IPR002172
DomainLDLa

LRP1B TMPRSS6 LRP1 LRP6

1.48e-03491884SM00192
DomainHemopexin-like_dom

MMP27 MMP24 MMP15

1.53e-03231883IPR000585
DomainHemopexin-like_repeat

MMP27 MMP24 MMP15

1.53e-03231883IPR018487
PathwayREACTOME_ION_CHANNEL_TRANSPORT

TTYH1 TRPM3 CLIC2 SCNN1A TPCN2 WWP1 ATP13A2 ATP8B2 ANO7 ATP12A

2.05e-0518314610M997
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TTYH1 SLC22A15 SLC24A3 ABCA7 ADCY9 HEPH BMP1 AP2A1 AP2A2 TRPM3 CLIC2 SCNN1A ADCY4 TPCN2 WWP1 ATP13A2 ATP8B2 TFR2 SLC9A5 ANO7 ATP12A

2.26e-0573614621M27287
PathwayWP_EFFECTS_OF_NITRIC_OXIDE

NOS1 NOS2 NOS3

5.87e-0581463M39677
PathwayREACTOME_ION_CHANNEL_TRANSPORT

TTYH1 TRPM3 SCNN1A TPCN2 WWP1 ATP13A2 ATP8B2 ANO7 ATP12A

8.97e-051761469MM15718
PathwayWP_UREA_CYCLE_AND_ASSOCIATED_PATHWAYS

NOS1 NOS2 NOS3 SLC25A12

9.99e-05241464M39850
PathwayREACTOME_STIMULI_SENSING_CHANNELS

TTYH1 TRPM3 CLIC2 SCNN1A TPCN2 WWP1 ANO7

1.15e-041061467M27200
PathwayKEGG_ARGININE_AND_PROLINE_METABOLISM

AOC1 NOS1 NOS2 NOS3 P4HA2

2.34e-04541465M2551
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TTYH1 SLC22A15 SLC24A3 ABCA7 HEPH BMP1 AP2A1 AP2A2 TRPM3 SCNN1A TPCN2 WWP1 ATP13A2 ATP8B2 TFR2 SLC9A5 ANO7 ATP12A

2.37e-0468114618MM14985
PathwayREACTOME_NITRIC_OXIDE_STIMULATES_GUANYLATE_CYCLASE

NOS1 NOS2 NOS3

2.88e-04131463MM15015
PathwayWP_NITRIC_OXIDE_METABOLISM_IN_CYSTIC_FIBROSIS

NOS1 NOS2 NOS3

2.88e-04131463M39894
PathwayWP_TYPE_I_COLLAGEN_SYNTHESIS_IN_THE_CONTEXT_OF_OSTEOGENESIS_IMPERFECTA

BMP1 P4HA2 COLGALT1 LRP6

3.58e-04331464M39870
Pubmed

HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways.

NOS1 NOS2 NOS3 LRP1

1.18e-079195424666322
Pubmed

Paradoxical roles of different nitric oxide synthase isoforms in colonic injury.

NOS1 NOS2 NOS3

1.74e-073195314665440
Pubmed

Deletion of neuronal NOS prevents impaired vasodilation in septic mouse skeletal muscle.

NOS1 NOS2 NOS3

1.74e-073195317258180
Pubmed

Differential expression of nitric oxide synthases (NOS 1-3) in human skeletal muscle following exercise countermeasure during 12 weeks of bed rest.

NOS1 NOS2 NOS3

1.74e-073195315180967
Pubmed

Decreased viability of nitric oxide synthase double knockout mice.

NOS1 NOS2 NOS3

1.74e-073195312704728
Pubmed

Molecular and biochemical characterization of nitric oxide synthase isoforms and their intracellular distribution in human peripheral blood mononuclear cells.

NOS1 NOS2 NOS3

1.74e-073195321722677
Pubmed

Nitric oxide is proangiogenic in the retina and choroid.

NOS1 NOS2 NOS3

1.74e-073195311920687
Pubmed

Contribution of nitric oxide synthases 1, 2, and 3 to airway hyperresponsiveness and inflammation in a murine model of asthma.

NOS1 NOS2 NOS3

1.74e-073195310330441
Pubmed

Differences in inflammatory pain in nNOS-, iNOS- and eNOS-deficient mice.

NOS1 NOS2 NOS3

1.74e-073195317395508
Pubmed

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

NOS1 NOS2 NOS3

1.74e-07319538943206
Pubmed

Reduced spinal microglial activation and neuropathic pain after nerve injury in mice lacking all three nitric oxide synthases.

NOS1 NOS2 NOS3

1.74e-073195321756313
Pubmed

Nitric oxide synthase expression and role during cardiomyogenesis.

NOS1 NOS2 NOS3

1.74e-073195310690339
Pubmed

Molecular control of nitric oxide synthases in the cardiovascular system.

NOS1 NOS2 NOS3

1.74e-073195310690323
Pubmed

Expression of nitric oxide synthases in leukocytes in nasal polyps.

NOS1 NOS2 NOS3

1.74e-073195322374200
Pubmed

Nitric oxide synthases: three pieces to the puzzle?

NOS1 NOS2 NOS3

1.74e-073195325366612
Pubmed

Genetic Models in Applied Physiology. Differential role of nitric oxide synthase isoforms in fever of different etiologies: studies using Nos gene-deficient mice.

NOS1 NOS2 NOS3

1.74e-073195312562678
Pubmed

Nitric oxide synthase isoforms play distinct roles during acute peritonitis.

NOS1 NOS2 NOS3

1.74e-073195319706695
Pubmed

Molecular architecture of mammalian nitric oxide synthases.

NOS1 NOS2 NOS3

1.74e-073195325125509
Pubmed

Relative contributions of endothelial, inducible, and neuronal NOS to tone in the murine pulmonary circulation.

NOS1 NOS2 NOS3

1.74e-073195310484454
Pubmed

Mechanisms and structural determinants of HIV-1 coat protein, gp41-induced neurotoxicity.

NOS1 NOS2 NOS3

1.74e-07319539870939
Pubmed

Severe dyslipidaemia, atherosclerosis, and sudden cardiac death in mice lacking all NO synthases fed a high-fat diet.

NOS1 NOS2 NOS3

1.74e-073195320304785
Pubmed

Nitric oxide synthases: which, where, how, and why?

NOS1 NOS2 NOS3

1.74e-07319539410890
Pubmed

Cellular and molecular mechanisms of endothelial cell dysfunction.

NOS1 NOS2 NOS3

1.74e-07319539410891
Pubmed

Nitric oxide synthase gene polymorphisms in functional dyspepsia.

NOS1 NOS2 NOS3

1.74e-073195324114042
Pubmed

Lessons from genetically engineered animal models. IV. Nitric oxide synthase gene knockout mice.

NOS1 NOS2 NOS3

1.74e-073195310516139
Pubmed

Leukocyte-endothelial cell interactions in nitric oxide synthase-deficient mice.

NOS1 NOS2 NOS3

1.74e-073195310362674
Pubmed

Defective fluid and HCO(3)(-) absorption in proximal tubule of neuronal nitric oxide synthase-knockout mice.

NOS1 NOS2 NOS3

1.74e-073195310966931
Pubmed

Role of nitric oxide synthase isoforms for ophthalmic artery reactivity in mice.

NOS1 NOS2 NOS3

1.74e-073195325017185
Pubmed

Nitric oxide synthase enzymes in the airways of mice exposed to ovalbumin: NOS2 expression is NOS3 dependent.

NOS1 NOS2 NOS3

1.74e-073195320953358
Pubmed

Functional consequences of the collagen/elastin switch in vascular remodeling in hyperhomocysteinemic wild-type, eNOS-/-, and iNOS-/- mice.

NOS1 NOS2 NOS3

1.74e-073195320581102
Pubmed

Expression profiles of NOS isoforms in gingiva of nNOS knockout mice.

NOS1 NOS2 NOS3

1.74e-073195324657074
Pubmed

Vascular biology in genetically altered mice : smaller vessels, bigger insight.

NOS1 NOS2 NOS3

1.74e-073195310590250
Pubmed

2-Aminopyridines with a shortened amino sidechain as potent, selective, and highly permeable human neuronal nitric oxide synthase inhibitors.

NOS1 NOS2 NOS3

1.74e-073195335772285
Pubmed

Perturbed neural activity disrupts cerebral angiogenesis during a postnatal critical period.

NOS1 NOS2 NOS3

1.74e-073195324305053
Pubmed

Lessons learned from nitric oxide synthase knockout animals.

NOS1 NOS2 NOS3

1.74e-073195310709868
Pubmed

Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization.

NOS1 NOS2 NOS3

1.74e-073195325813085
Pubmed

Limb reduction defects in endothelial nitric oxide synthase-deficient mice.

NOS1 NOS2 NOS3

1.74e-07319539843834
Pubmed

Protective roles of nitric oxide and testosterone in endotoxemia: evidence from NOS-2-deficient mice.

NOS1 NOS2 NOS3

1.74e-07319539843821
Pubmed

High-protein-induced glomerular hyperfiltration is independent of the tubuloglomerular feedback mechanism and nitric oxide synthases.

NOS1 NOS2 NOS3

1.74e-073195320739607
Pubmed

Expression of nitric oxide synthase isoforms in human pregnant myometrium at term.

NOS1 NOS2 NOS3

1.74e-073195312445599
Pubmed

Rate and severity of HIV-associated dementia (HAD): correlations with Gp41 and iNOS.

NOS1 NOS2 NOS3

1.74e-073195310203575
Pubmed

Analysis of nitric oxide synthase genes in cluster headache.

NOS1 NOS2 NOS3

1.74e-073195312421162
Pubmed

Partial cloning of constitutive and inducible nitric oxide synthases and detailed neuronal expression of NOS mRNA in the cerebellum and optic tectum of adult Atlantic salmon (Salmo salar).

NOS1 NOS2 NOS3

1.74e-073195310891583
Pubmed

Relative contributions of NOS isoforms during experimental colitis: endothelial-derived NOS maintains mucosal integrity.

NOS1 NOS2 NOS3

1.74e-073195315217783
Pubmed

Human immunodeficiency virus-1-infected macrophages induce inducible nitric oxide synthase and nitric oxide (NO) production in astrocytes: astrocytic NO as a possible mediator of neural damage in acquired immunodeficiency syndrome.

NOS1 NOS2 NOS3

1.74e-073195310068656
Pubmed

Crucial roles of nitric oxide synthases in β-adrenoceptor-mediated bladder relaxation in mice.

NOS1 NOS2 NOS3

1.74e-073195327784691
Pubmed

Nitric oxide synthase gene knockout mice do not become hypertensive during pregnancy.

NOS1 NOS2 NOS3

1.74e-073195311717657
Pubmed

Estrogen induces nitric oxide production via activation of constitutive nitric oxide synthases in human neuroblastoma cells.

NOS1 NOS2 NOS3

1.74e-073195315242984
Pubmed

Secretagogue-stimulated pancreatic secretion is differentially regulated by constitutive NOS isoforms in mice.

NOS1 NOS2 NOS3

1.74e-073195314551061
Pubmed

Nitric oxide synthases and heart failure - lessons from genetically manipulated mice.

NOS1 NOS2 NOS3

1.74e-073195323774658
Pubmed

Human immunodeficiency virus infection, inducible nitric oxide synthase expression, and microglial activation: pathogenetic relationship to the acquired immunodeficiency syndrome dementia complex.

NOS1 NOS2 NOS3

1.74e-073195310443886
Pubmed

Nitric oxide synthase polymorphisms, gene expression and lung function in chronic obstructive pulmonary disease.

NOS1 NOS2 NOS3

1.74e-073195324192154
Pubmed

[Polymorphic markers of the NO synthase genes and genetic predisposition to diabetic polyneuropathy in patients with type 1 diabetes mellitus].

NOS1 NOS2 NOS3

1.74e-073195315856945
Pubmed

Metabolic profile and nitric oxide synthase expression of skeletal muscle fibers are altered in patients with type 1 diabetes.

NOS1 NOS2 NOS3

1.74e-073195318465682
Pubmed

Subunit interactions of endothelial nitric-oxide synthase. Comparisons to the neuronal and inducible nitric-oxide synthase isoforms.

NOS1 NOS2 NOS3

1.74e-07319538995432
Pubmed

nNOS deficiency-induced cell proliferation depletes the neurogenic reserve.

NOS1 NOS2 NOS3

1.74e-073195322027181
Pubmed

Pulmonary nitric oxide synthases and nitrotyrosine: findings during lung development and in chronic lung disease of prematurity.

NOS1 NOS2 NOS3

1.74e-073195316950998
Pubmed

Crucial role for neuronal nitric oxide synthase in early microcirculatory derangement and recipient survival following murine pancreas transplantation.

NOS1 NOS2 NOS3

1.74e-073195325389974
Pubmed

Increase in Red Blood Cell-Nitric Oxide Synthase Dependent Nitric Oxide Production during Red Blood Cell Aging in Health and Disease: A Study on Age Dependent Changes of Rheologic and Enzymatic Properties in Red Blood Cells.

NOS1 NOS2 NOS3

1.74e-073195325902315
Pubmed

Alterations in nitric oxide synthase isoforms in acute lower limb ischemia and reperfusion.

NOS1 NOS2 NOS3

1.74e-073195318024942
Pubmed

mRNA expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and neuronal nitric oxide synthase genes in meningitis patients.

NOS1 NOS2 NOS3

1.74e-073195321204701
Pubmed

Nitric oxide synthase in the vestibulocochlear system of mice.

NOS1 NOS2 NOS3

1.74e-07319539824677
Pubmed

Exhaled nitric oxide production by nitric oxide synthase-deficient mice.

NOS1 NOS2 NOS3

1.74e-073195311029328
Pubmed

Cardiovascular and renal control in NOS-deficient mouse models.

NOS1 NOS2 NOS3

1.74e-073195312571071
Pubmed

Contribution of nitric oxide synthase isoforms to cholinergic vasodilation in murine retinal arterioles.

NOS1 NOS2 NOS3

1.74e-073195323434456
Pubmed

Different expression of NOS isoforms in early endothelial progenitor cells derived from peripheral and cord blood.

NOS1 NOS2 NOS3

1.74e-073195317492662
Pubmed

Immunohistochemical evaluation of three nitric oxide synthase isoforms in human saphenous vein exposed to different degrees of distension pressures.

NOS1 NOS2 NOS3

1.74e-073195320060328
Pubmed

Crucial role of nitric oxide synthases system in endothelium-dependent hyperpolarization in mice.

NOS1 NOS2 NOS3

1.74e-073195318695006
Pubmed

Nephrogenic diabetes insipidus in mice lacking all nitric oxide synthase isoforms.

NOS1 NOS2 NOS3

1.74e-073195316024729
Pubmed

Hypoxic vasodilation by red blood cells: evidence for an s-nitrosothiol-based signal.

NOS1 NOS2 NOS3

1.74e-073195318658051
Pubmed

Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction.

NOS1 NOS2 NOS3

1.74e-073195321890687
Pubmed

Reductase domain cysteines 1048 and 1114 are critical for catalytic activity of human endothelial cell nitric oxide synthase as probed by site-directed mutagenesis.

NOS1 NOS2 NOS3

1.74e-07319538806629
Pubmed

Role of NO synthase in the development of Trypanosoma cruzi-induced cardiomyopathy in mice.

NOS1 NOS2 NOS3

1.74e-073195319407124
Pubmed

The Functional Diversity of Nitric Oxide Synthase Isoforms in Human Nose and Paranasal Sinuses: Contrasting Pathophysiological Aspects in Nasal Allergy and Chronic Rhinosinusitis.

NOS1 NOS2 NOS3

1.74e-073195334299181
Pubmed

Obesity, insulin resistance, and skeletal muscle nitric oxide synthase.

NOS1 NOS2 NOS3

1.74e-073195322797309
Pubmed

Association between achalasia and nitric oxide synthase gene polymorphisms.

NOS1 NOS2 NOS3

1.74e-073195316848803
Pubmed

Relaxation of myometrium by calcitonin gene-related peptide is independent of nitric oxide synthase activity in mouse uterus.

NOS1 NOS2 NOS3

1.74e-073195311058547
Pubmed

Genetic disruption of all NO synthase isoforms enhances BMD and bone turnover in mice in vivo: involvement of the renin-angiotensin system.

NOS1 NOS2 NOS3

1.74e-073195318433298
Pubmed

Substance P enhances wound closure in nitric oxide synthase knockout mice.

NOS1 NOS2 NOS3

1.74e-073195318952239
Pubmed

Autoregulation of nitric oxide-soluble guanylate cyclase-cyclic GMP signalling in mouse thoracic aorta.

NOS1 NOS2 NOS3

1.74e-073195310556946
Pubmed

Nitric oxide synthase isoforms undertake unique roles during excitotoxicity.

NOS1 NOS2 NOS3

1.74e-073195317446423
Pubmed

Nitric oxide synthases and protein oxidation in the quadriceps femoris of patients with chronic obstructive pulmonary disease.

NOS1 NOS2 NOS3

1.74e-073195312816735
Pubmed

Spontaneous myocardial infarction in mice lacking all nitric oxide synthase isoforms.

NOS1 NOS2 NOS3

1.74e-073195318413498
Pubmed

Biochemistry of soluble guanylate cyclase.

NOS1 NOS2 NOS3

1.74e-073195319089323
Pubmed

Common polymorphisms in nitric oxide synthase (NOS) genes influence quality of aging and longevity in humans.

NOS1 NOS2 NOS3

1.74e-073195323572278
Pubmed

The role of inducible nitric oxide synthase in gamete interaction and fertilization: a comparative study on knockout mice of three NOS isoforms.

NOS1 NOS2 NOS3

1.74e-073195316087361
Pubmed

Association analysis of nitric oxide synthases: NOS1, NOS2A and NOS3 genes, with multiple sclerosis.

NOS1 NOS2 NOS3

1.74e-073195323826716
Pubmed

Analysis of 16 STRs of NOS gene regions and around in six Sardinian populations (Italy).

NOS1 NOS2 NOS3

1.74e-073195324573959
Pubmed

[Role of nitric oxide synthases in the pathogenesis of cardiovascular disease].

NOS1 NOS2 NOS3

1.74e-073195324813792
Pubmed

Ultrastructural immunogold localization of nitric oxide synthase isoforms in rat and human eosinophils.

NOS1 NOS2 NOS3

1.74e-073195320232214
Pubmed

Differential roles of nitric oxide synthases in regulation of ultraviolet B light-induced apoptosis.

NOS1 NOS2 NOS3

1.74e-073195320547234
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

VPS13C STARD10 NFASC PTK7 JOSD2 ATXN7 SCNN1A CACNA1H SMURF2 SLC37A1 TPCN2 PPFIBP2 TMPRSS6 WWP1 TMEM63C IDE JMJD1C SNX29 RLF SPTBN4 LRP1 CCAR1 CTBP2 ARHGEF26 CATSPERG CDH15

3.03e-0714891952628611215
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1B SHH LRP1 LRP6

3.07e-0711195424639464
Pubmed

Control of disease tolerance to malaria by nitric oxide and carbon monoxide.

NOS1 NOS2 NOS3

6.91e-074195324981859
Pubmed

Structure and dynamics of calmodulin (CaM) bound to nitric oxide synthase peptides: effects of a phosphomimetic CaM mutation.

NOS1 NOS2 NOS3

6.91e-074195322486744
Pubmed

Reduced arteriolar conducted vasoconstriction in septic mouse cremaster muscle is mediated by nNOS-derived NO.

NOS1 NOS2 NOS3

6.91e-074195316226732
Pubmed

Expression of nitric oxide synthase isoforms in the mouse kidney: cellular localization and influence by lipopolysaccharide and Toll-like receptor 4.

NOS1 NOS2 NOS3

6.91e-074195316733795
Pubmed

Enhanced XOR activity in eNOS-deficient mice: Effects on the nitrate-nitrite-NO pathway and ROS homeostasis.

NOS1 NOS2 NOS3

6.91e-074195327609225
Pubmed

Transient expression of NOS-II during development of the murine enteric nervous system.

NOS1 NOS2 NOS3

6.91e-074195315609086
Pubmed

Effects of nitric oxide synthase deficiency on a disintegrin and metalloproteinase domain-containing protein 12 expression in mouse brain samples.

NOS1 NOS2 NOS3

6.91e-074195325892053
Cytoband1q24

ADCY10 RABGAP1L BRINP2

8.16e-052019531q24
GeneFamilyAdenylate cyclases|Deafness associated genes

ADCY10 ADCY9 ADCY4

3.39e-0510121353
GeneFamilyLow density lipoprotein receptors

LRP1B LRP1 LRP6

7.96e-05131213634
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT1 GGTLC3 GGT2P

7.96e-05131213564
GeneFamilyArylamine N-acetyltransferases

NAT1 NAT2

1.33e-04312121133
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP27 MMP24 MMP15

5.34e-04241213891
GeneFamilyChloride intracellular channels

CLIC2 CLIC4

6.55e-0461212307
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW2 FBXW5

2.35e-03111212559
CoexpressionGSE39152_SPLEEN_CD103_NEG_VS_BRAIN_CD103_POS_MEMORY_CD8_TCELL_DN

SART3 ADCY9 ITIH3 PHEX PLA2G5 ZFP28 COLGALT1 C11orf16 LRP1 FIGNL1

2.48e-0620019310M9067
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|metastatic_Brain / Location, Cell class and cell subclass

MYO7B RS1 CLIC2 NAALADL1 ANPEP NFKBID SLC46A3 TLR3

1.08e-061761948b9ba7026dee2272c0b483dc0cfa39f74b75f1634
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 PIWIL1 STARD10 ST8SIA5 KLB C11orf16 SPTBN4 IHH

1.23e-061791948d70791d2a0db35a6b013fa7ed2f9f39364581eff
ToppCell10x5'-Lung-Myeloid_Dendritic-migDC|Lung / Manually curated celltypes from each tissue

AOC1 ETV6 RS1 CRLF2 CLIC2 NFKBID PPA1 VANGL2

1.28e-061801948e9e8992deb0beeee5548910e4616e7c990763d99
ToppCell21-Trachea-Mesenchymal-Mesenchyme_SERPINF1-high|Trachea / Age, Tissue, Lineage and Cell class

DCHS2 BMP1 TRPM3 PLA2G5 KDELR3 BRINP2 CDH15 PLAAT5

1.39e-061821948354dcdb01360597f68c4fe157a682aee1c0b8bb1
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC BMP1 MMP15 KLB ANPEP TMPRSS6 TFR2 MAPK15

1.39e-06182194877ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC BMP1 MMP15 KLB ANPEP TMPRSS6 TFR2 MAPK15

1.39e-0618219484921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC BMP1 MMP15 KLB ANPEP TMPRSS6 TFR2 MAPK15

1.39e-061821948770ce9f3f4538d0181a0181543841bc964c68274
ToppCell5'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

BNC2 SLC24A3 CRLF2 NDST2 NFKBID IDS SNX29 RASGEF1B

1.85e-061891948f01158bb15df3117fae1271bf8cf8c2501422671
ToppCell(3)_DC_activated|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

TSPAN15 AOC1 ETV6 CRLF2 ARHGAP22 MMP24 CLIC2 SYNGR2

1.85e-061891948e977838793fc0eb1499e81018e33e4ccb4a5f0c5
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 ETV6 CRLF2 ARHGAP22 CLIC2 NFKBID PPA1 SYNGR2

1.92e-0619019482ff4b50b864a35f22c558d7d585cd2b54612b50c
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 ETV6 CRLF2 ARHGAP22 CLIC2 NFKBID PPA1 SYNGR2

1.92e-0619019485175bf022d55a52988014abe7cece326a8406a38
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH1 LRP1B HEPH SCNN1A KCNT1 FA2H TMPRSS6 MAPK15

1.92e-06190194868ba1934b2b3f0cec8efd229fe1db6e8be8a26b0
ToppCellfacs-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH1 LRP1B HEPH SCNN1A KCNT1 FA2H TMPRSS6 MAPK15

1.92e-061901948010d7d13a3c16e614c36720ef690a505b9f3f7aa
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 ETV6 CRLF2 ARHGAP22 CLIC2 NFKBID PPA1 SYNGR2

1.92e-06190194829e60b9b1c86b44550619c01306b8b1bb2e340dc
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SLC22A15 COG6 PLA2G5 ENTPD7 KDELR3 SLC25A12 ANO7

2.24e-0619419480797245ebfa389a6f66874cb0f11297f1456e600
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC SLC22A15 COG6 PLA2G5 ENTPD7 KDELR3 SLC25A12 ANO7

2.24e-0619419480241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Glia_progenitor_cell|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ADCY9 BMP1 ARL13B TSEN34 DNAH6 BRMS1L MAPK15 LPIN2

2.42e-0619619487be50b9156394dea44d7b8b476d4dd516abfafae
ToppCellParenchymal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCN11A AOC1 ETV6 CRLF2 ARHGAP22 CLIC2 NFKBID PLXNC1

2.71e-061991948f4ab29f99ce45a3044d2e9f356dc24d3c5e7121f
ToppCellnucseq-Immune-Hematopoietic-Granulocytic-Mast/Basophil|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BNC2 SLC24A3 LRP1B CRLF2 CACNA1H NDST2 SKAP1

8.13e-061651947640bb71e74a61df2fcb01ceeabe4c493ef836b21
ToppCellnucseq-Immune-Hematopoietic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BNC2 SLC24A3 LRP1B CRLF2 CACNA1H NDST2 SKAP1

8.13e-061651947f3df74b5763130c71c0a482a3a23f6b22acc2892
ToppCellnucseq-Immune-Hematopoietic-Granulocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

BNC2 SLC24A3 LRP1B CRLF2 CACNA1H NDST2 SKAP1

8.13e-06165194737615622c736e43260c38016e7c9e565ac97a3e8
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH1 NAT1 ACSS1 NEUROG1 TPCN2 TMPRSS6 ARHGEF26

8.80e-0616719472184c2760b6142e62124a2454a552723e20d4f61
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MKS1 ARHGAP22 ANPEP PPFIBP2 ZFP28 SLC46A3 TLR3

8.80e-061671947f33cef917fa733adf6d5a9a9e989a4d9fd462a8f
ToppCellControl-Mast_cells|Control / group, cell type (main and fine annotations)

BNC2 SLC24A3 LRP1B CRLF2 CACNA1H NDST2 SKAP1

9.51e-061691947fdb9abca1d0f4fdc32dd8ac6231651ef34aa5afb
ToppCellControl-Mast_cells-Mast_cells|Control / group, cell type (main and fine annotations)

BNC2 SLC24A3 LRP1B CRLF2 CACNA1H NDST2 SKAP1

9.88e-061701947c80f6d29096c372da95a8407f402349ff1bb7018
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|(2)_5-FU / Stress and Cell class

BMP1 PKD1 KDELR3 P4HA2 ANPEP PPFIBP2 TMPRSS6

1.48e-05181194756ae86072858c156681507aecd1bc6cb0a3372d2
ToppCellPCW_05-06-Neuronal-Neuronal_SCP|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TTYH1 NFASC NEUROG1 TRPM3 ST8SIA5 MMP15 CRB1

1.54e-051821947b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC BMP1 MMP15 KLB ANPEP TMPRSS6 TFR2

1.59e-051831947d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO7B TRPM3 MGAM P4HA2 ANPEP CLIC4 SNX29

1.65e-0518419479434731f651820b05335085582960f08fbf895de
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

BMP1 PKD1 KDELR3 P4HA2 ANPEP TMPRSS6 LRP1

1.65e-051841947684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSS1 F8 HEPH TRPM3 ATXN7 TPCN2

1.66e-051231946a45d6907c041ad3f3218cd46dccfc25d4bd961cb
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TSPAN15 NOS2 NOS3 TRHDE ADCY4 TFR2 RSAD2

1.71e-05185194762cfcb0e2a9e6718e6b200dfbb1a81eaead229b5
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|normal_Lung / Location, Cell class and cell subclass

SCN11A AOC1 CRLF2 ARHGAP22 CLIC2 PPA1 SYNGR2

1.77e-0518619470987c9a39503eb6c75a2bf4db98b2b2fd46956fb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY9 KL TRPM3 MGAM P4HA2 ANPEP SNX29

1.77e-0518619475784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCellnormal_Lung-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

SCN11A AOC1 CRLF2 ARHGAP22 CLIC2 NOS1 PPA1

1.77e-05186194700ad1239b952119b3fd2e6af8f034cba3488f9c1
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC PLA2G5 ASCC3 ENTPD7 KDELR3 CLIC4 PPA1

1.83e-051871947ab109aa51beae3df474c15002e70361f328cadad
ToppCellfacs-Large_Intestine-Distal-18m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC PLA2G5 ASCC3 ENTPD7 KDELR3 CLIC4 PPA1

1.83e-051871947a4c408fc941d2e8a811a26aa916c0b3e3341163a
ToppCelldroplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BMP1 ASPM ARHGAP23 TMPRSS6 TFR2 GSDMA FIGNL1

1.89e-0518819471a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCellMesenchymal_cells-Osteoblasts|World / Lineage and Cell class

PHEX BMP1 PLA2G5 KDELR3 P4HA2 PPFIBP2 CDH15

1.89e-05188194789f7f5a51be7e046a63e2413f86c521ae4b6718f
ToppCellNeuronal_cells-Schwann_cells|World / Lineage and Cell class

NFASC NKAIN2 LRP1B ITIH3 ARC ST8SIA5 FA2H

1.96e-051891947371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCellNeuronal_cells|World / Lineage and Cell class

NFASC NKAIN2 LRP1B ITIH3 ARC ST8SIA5 FA2H

1.96e-0518919473948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

TSPAN15 SCN11A AOC1 ARHGAP22 CLIC2 NOS1 PLXNC1

2.03e-05190194715978ddd37b521343f88b62dad1643077fc22b2b
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

BNC2 KCNH7 SLC24A3 LRP1B ITIH3 PHEX HTR1E

2.10e-051911947156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 NFKBID IDS JMJD1C SNX29 SYNGR2 RASGEF1B

2.32e-051941947d852aebf7a763b9a776c4570711f0c759f591910
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Activated_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

TSPAN15 AOC1 CRLF2 CLIC2 NOS1 PPA1 SYNGR2

2.32e-051941947219056d4ad256cda73208b8c570bbf689219df83
ToppCellnormal_Pleural_Fluid-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

TSPAN15 AOC1 CRLF2 CLIC2 NOS1 PPA1 SYNGR2

2.32e-05194194730f683725cb13ae32ef6846618801ec78e12397d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 NFKBID IDS JMJD1C SNX29 SYNGR2 RASGEF1B

2.40e-051951947481989d2e5bd2582da3d86b0155c4d6615317067
ToppCell367C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CLIC2 ALOX15 VCPIP1 NAALADL1 ANPEP CLIC4 JMJD1C

2.40e-051951947fca958f73de450ef813444d3dc590353f1c55326
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 NFKBID IDS JMJD1C SNX29 SYNGR2 RASGEF1B

2.40e-0519519476108a27523d1b93a7fbe35cb95704a5ad9071e3c
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 CRLF2 ARHGAP22 CLIC2 NFKBID PPA1 SYNGR2

2.56e-0519719472a140c61e81aa18de2c9c1c443e314d6f09cdc18
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 CRLF2 ARHGAP22 CLIC2 NFKBID PPA1 SYNGR2

2.56e-051971947fa3fe934bd5fd8c6520a9c46357f9e441c794aba
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-dendritic_cell-Migratory_DCs-Migratory_DCs_L.1.2.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AOC1 CRLF2 ARHGAP22 CLIC2 NFKBID PPA1 SYNGR2

2.56e-05197194732eb4437cc608b8369e376446d639497ecfdd17a
ToppCellproximal-Endothelial-Artery-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYO7B NKAIN2 F8 ARC NOS1 NOS3 ADCY4

2.64e-051981947a56b80bdc824e4cc60366f273fb616cd0efec456
ToppCellproximal-3-Endothelial-Artery|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYO7B NKAIN2 F8 ARC NOS1 NOS3 ADCY4

2.64e-051981947946f72b594d22ae7b8e4c22483814c284cb43eea
ToppCellBronchial-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RS1 GGT1 MMP24 GGTLC3 SCNN1A LRP6 ARHGEF26

2.64e-05198194754228dd9a50616d2022712d162a419ed0327cabd
ToppCellproximal-Endothelial-Artery|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

MYO7B NKAIN2 F8 ARC NOS1 NOS3 ADCY4

2.64e-0519819470e5572298676b6c2a2b1a77967574020b664aebd
ToppCellLPS_anti-TNF-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FBXW2 JOSD2 ASPM ALOX15 TMEM63C TFR2 LPIN2

2.73e-051991947565404c155dfac57c020a8f2d09cbf756da20ffd
ToppCellTracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCN11A MYO7B NKAIN2 F8 KL NOS3 ADCY4

2.73e-0519919479735a1dc10910f02f1106b20ae5ab4c09c21305e
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCN11A AOC1 ETV6 CRLF2 ARHGAP22 CLIC2 NFKBID

2.82e-052001947a4c41509ca936e137230a6ae548c90f18a566d12
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DCHS2 CACNA1H DNAH6 SHH SKAP1 ATP12A

4.05e-05144194608005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEPH PHEX KCNT1 P4HA2 TMPRSS6 SKAP1

6.10e-051551946c58a5fb8d853f12204e961d633e83452eb12a659
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEPH PHEX KCNT1 P4HA2 TMPRSS6 SKAP1

6.10e-0515519469cb8c42c2e451b2d4dcd7154a4b1bfd21bbb7ea8
ToppCellAdult-Immune-mast_cell-D122|Adult / Lineage, Cell type, age group and donor

BNC2 SLC24A3 LRP1B MEI4 FBXO48 SKAP1

6.10e-0515519467c9de0591d1bf756b8e268b278bbe10bd5415dcd
ToppCellControl-Epithelial-Ionocyte|Epithelial / Disease state, Lineage and Cell class

STARD10 HLA-H CACNA1H KBTBD6 VANGL2 PLAAT5

6.10e-0515519464b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c4-RSAD2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MYO7B DNAH6 SHH RSAD2 PLXNC1 GPR68

6.32e-051561946f5889a6899904dfb7f596600b3a76857cf9d5378
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HGFAC ITIH3 BMP1 ANPEP TMPRSS6 TFR2

6.32e-051561946e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 PKD1 TPCN2 ANPEP GPR68 TLR3

6.55e-0515719465d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP22 PKD1 TPCN2 ANPEP GPR68 TLR3

6.55e-051571946ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFASC ARHGAP22 ARC MAB21L3 PLXNC1 SYNGR2

7.27e-0516019467db30647b596f0c419087e6fabb9b99dcd5bddd4
ToppCellPND07-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NFASC ARHGAP22 ARC MAB21L3 PLXNC1 SYNGR2

7.27e-05160194601f22cdb2a2f73776b7f91746e95c1850df94235
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NFASC ADCY9 TMEM63C RAD50 MAPK15 CATSPERG

7.27e-051601946955acb023ce4ccfac5073c9d693db87db3856187
ToppCellAdult-Immune-mast_cell|Adult / Lineage, Cell type, age group and donor

BNC2 STARD10 SLC24A3 MEI4 TMPRSS6 SKAP1

7.53e-05161194644f5c0256b3ce264a6c7b62740f32dcd45ee052d
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

AOC1 ABCA7 CRLF2 ARHGAP22 CLIC2 NOS1

7.53e-051611946cd41abb7ae659d3d314281783a0aaad562b26037
ToppCellsevere_influenza-cDC|severe_influenza / disease group, cell group and cell class (v2)

TSPAN15 AOC1 CALHM3 LRP1B CLIC2 ALOX15

7.53e-0516119467716315b8bda904b346cea47edc2c0b507a345c2
ToppCell10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-HSC/MPP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

NAT2 AOC1 NKAIN2 MEI4 NAALADL1 CRYGD

7.79e-051621946e73c644ce1db34f1d390878954e86fa0b3a455a1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

RABGAP1L SLC37A1 NFKBID JMJD1C SNX29 SYNGR2

8.06e-0516319466bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellfacs-Aorta-Heart-24m-Endothelial-coronary_vascular_endothelial_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAT2 RS1 MMP15 NOS2 ADCY4 CRYGD

8.33e-0516419465ee3729fab794d7acb172d14ec5d91aa1a61cd61
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 ANPEP MAB21L3 TLR3 RASGEF1B ATP12A

8.33e-051641946758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VWA5B2 KCNH7 GGTLC3 MGAM TMPRSS6 TMEM63C

8.91e-051661946afba41e15478053f11815acf568d29187de75492
ToppCellLV-11._Adipocyte|World / Chamber and Cluster_Paper

SLC24A3 KLB TRHDE PPA1 SYNE3 PLAAT5

8.91e-0516619467e5852891714465c6228c9f955fd511ec79d0e02
ToppCell356C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

SCN11A KLB NAALADL1 ANPEP ARHGAP23 LRP6

8.91e-051661946971ee6602a1e751f453f9d823295e63dadce62bf
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TTYH1 NKAIN2 ST8SIA5 NOS1 ALOX15 CRB1

9.51e-051681946948d9e9972bd2a4b503d55fa69b70dd568a35a67
ToppCelldroplet-Lung-nan-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARC FBXO48 ANPEP SLC9A5 GPR68 FIGNL1

9.51e-05168194696f7411474edd673b8d3ee6b8a8bb185c246daaf
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ETV6 CRLF2 ARHGAP22 SLC46A3 PLXNC1 SYNGR2

9.51e-0516819462c996d09b6a8ccd3c708146eca310b02eafff425
ToppCellfacs-Marrow-KLS-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH1 ARHGAP22 SLC46A3 SLC9A5 TLR3 CDH15

9.83e-051691946d6ad3b637de2935c656aad47ad82d6e8a8bd1227
ToppCellfacs-Marrow-KLS-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTYH1 ARHGAP22 SLC46A3 SLC9A5 TLR3 CDH15

9.83e-05169194660ef186518d0dc63dbded2a77c65cfe3129df754
ToppCelldroplet-Lung-nan-21m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GP1BA ANPEP NFKBID PLXNC1 SYNGR2 CATSPERG

1.02e-041701946d72eb77271d61e27a3d247149561c7f45fadb28b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DCHS2 NFASC LRP1B PPFIBP2 PLXNC1 LRP1

1.02e-0417019465570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellILEUM-non-inflamed-(3)_mature_DC|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

AOC1 CRLF2 ARHGAP22 CLIC2 SLC9A5 SYNGR2

1.02e-04170194660151394460e6f27a42fab434e8b7b2adc78b128
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC1|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

TNK1 CLIC2 ALOX15 ANPEP SLC46A3 TLR3

1.05e-041711946459e1ac0b89571c39db98c0f578eca8f46caa8e3
ToppCellwk_15-18-Hematologic-Myeloid-Mast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

AOC1 SLC24A3 CRLF2 CRYGD SKAP1 CDH15

1.08e-041721946a7146c255031207e64682ef767884b11c96e0d59
ToppCell3'_v3-lymph-node_spleen-Myeloid_Dendritic-migDC|lymph-node_spleen / Manually curated celltypes from each tissue

SCN11A AOC1 CRLF2 ARHGAP22 CLIC2 NOS1

1.08e-0417219461b24bed3cd8e3fa463c5e7cefdf9e99e639e2f84
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)-|368C / Donor, Lineage, Cell class and subclass (all cells)

F8 KL ARC NOS1 NOS3 ADCY4

1.12e-041731946ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell367C-Myeloid-Dendritic-cDC_activated|367C / Donor, Lineage, Cell class and subclass (all cells)

TSPAN15 AOC1 ARHGAP22 CLIC2 ENTPD7 PPA1

1.12e-04173194694f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSPAN15 AOC1 CRLF2 ARHGAP22 CLIC2 NOS1

1.12e-04173194609a13407a41ff2cba82fc417b72bf9a24ce6c42e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_10|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TSPAN15 AOC1 CRLF2 ARHGAP22 CLIC2 NOS1

1.12e-041731946bfec038a6783f166240da4861e100643c6ea80a5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC37A1 NFKBID JMJD1C SNX29 SYNGR2 RASGEF1B

1.12e-041731946d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCell368C-Endothelial_cells-Endothelial-B_(Artery)|368C / Donor, Lineage, Cell class and subclass (all cells)

F8 KL ARC NOS1 NOS3 ADCY4

1.12e-04173194622200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

BNC2 TRPM3 MGAM P4HA2 ANPEP SNX29

1.12e-0417319468888434641ea554a9b62c436e87920378eef29cd
ToppCellLV-11._Adipocyte|LV / Chamber and Cluster_Paper

SLC24A3 KLB TRHDE PPA1 SYNE3 PLAAT5

1.12e-041731946c2d3fcb3de71015d03d14c63450853d2b03ffa71
Drugcobalt-60

NAT1 ADCY9 HEPH GGT1 BMP1 PKD1 CACNA1H NOS2 NOS3 MGAM ADCY4 TPCN2 ANPEP IDE PPA1 GBA2 TFR2

3.57e-0839019117CID000061492
Drug3-Bromo-7-Nitroindazole

NOS1 NOS2 NOS3

5.81e-0731913DB01997
DrugN-(3-(Aminomethyl)Benzyl)Acetamidine

NOS1 NOS2 NOS3

5.81e-0731913DB02044
DrugMetanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; MCF7; HT_HG-U133A

AOC1 VPS13C PIWIL1 PHEX AP2A2 CACNA1H NOS1 NDST2 ATP8B2 SNX29 ARHGEF26

8.71e-07196191111515_UP
DrugB-H-H

NOS1 NOS2 NOS3 SHH

2.25e-06121914CID000447030
DrugAC1LCT6N

NAT1 NAT2 MGAM SPEN

2.25e-06121914CID000606283
Drug(6r,1'r,2's)-5,6,7,8 Tetrahydrobiopterin

NOS1 NOS2 NOS3

2.31e-0641913DB02692
DrugN-Omega-Hydroxy-L-Arginine

NOS1 NOS2 NOS3

2.31e-0641913DB03144
DrugS-isopropylisothiourea

NOS1 NOS3 MGAM NGLY1

3.23e-06131914CID000445319
DrugNocloprostum

ADCY9 NOS1 NOS2 NOS3 ADCY4

3.31e-06281915CID006435380
DrugAC1L9T0X

NOS1 NOS2 NOS3 SPEN

4.50e-06141914CID000500472
Drugl956

AOC1 NOS1 NOS2 NOS3

6.09e-06151914CID000017814
DrugTrimipramine maleate salt [521-78-8]; Down 200; 9.8uM; MCF7; HT_HG-U133A

BMP1 AP2A2 RABGAP1L SCAPER MMP15 TMUB2 HTR1E NDST2 SLC46A3 ZNF277

6.46e-06196191103342_DN
Drugcopper

NAT2 AOC1 ZMPSTE24 ADCY9 HEPH CACNA1H NOS1 NOS2 NOS3 ALOX15 MGAM P4HA2 ADCY4 PPA1 GBA2 MAPK15 LRP6

6.96e-0657119117CID000023978
DrugnaBE

NOS1 NOS2 NOS3 MGAM

1.05e-05171914CID000151475
DrugN-nitroso-L-arginine

NOS1 NOS2 NOS3

1.14e-0561913CID000127762
DrugNapNa

NOS1 NOS2 NOS3

1.14e-0561913CID000128726
Drug5 fA

ACSS1 MGAM PPA1

1.14e-0561913CID000193491
Drug1-hexacosanol

NOS1 NOS2 NOS3

1.14e-0561913ctd:C051942
Drugverapamil

ADCY10 KCNH7 ABCA7 ADCY9 KL PKD1 SCNN1A CACNA1H NOS1 NOS2 NOS3 MGAM ADCY4 TPCN2 PDCD6

1.78e-0549019115CID000002520
Drugiloprost

ADCY10 ADCY9 NOS1 NOS2 NOS3 ALOX15 GP1BA ADCY4

1.79e-051341918CID005311181
Drugchloride

GABRG2 NAT1 ACSS1 ADCY9 GGT1 PHEX AP2A1 AP2A2 CLIC2 PKD1 SCNN1A NOS2 NOS3 GP1BA MGAM ADCY4 HTR1E CLIC4 CRYGD SLC9A5 MAPK15 LRP6 NGLY1

1.86e-05102919123CID000000312
DrugAC1NLRUC

NOS1 NOS2 NOS3

1.98e-0571913CID004988604
DrugAC1L1KRE

PHEX NOS1 NOS2 NOS3

2.09e-05201914CID000005622
Drugglabridin

NOS1 NOS2 NOS3 MAPK15 SPEN

2.93e-05431915CID000124052
DrugMiconazole

KCNH7 NOS2 NOS3

3.16e-0581913DB01110
Drugudenafil

NOS1 NOS3 SHH

3.16e-0581913ctd:C419664
Drugpotassium hydroxide

KL NOS1 NOS2 NOS3 MGAM GBA2 PLXNC1

3.57e-051081917CID000014797
DrugAC1NPJ0Q

NAT1 NAT2 ETV6 ADCY9 PIK3R4 ADCY4

3.72e-05741916CID005159167
Drugatropine sulfate

ADCY10 GABRG2 ADCY9 PTK7 CLIC2 NOS1 NOS2 NOS3 ADCY4 ANPEP CLIC4 CRYGD

3.93e-0534719112CID000003661
Drug17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A

GABRG2 AOC1 NOS1 GP1BA KDELR3 P4HA2 PLXNC1 LRP1 CDH15

4.16e-0519519196172_UP
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

DCHS2 ADCY9 ARHGAP22 BMP1 MMP24 SCNN1A CRB1 GPR68 LRP1

4.33e-0519619195771_UP
Drugmangrove

ZMPSTE24 ACSS1 LRP1B ADCY9 NOS1 NOS2 NOS3 ALOX15 ADCY4 ANPEP SLC25A12 G6PC3 LRP1 LRP6

4.38e-0546819114CID000000965
Drug4-phenylimidazole

NOS1 NOS2 NOS3 GBA2

4.47e-05241914CID000069590
DrugUrapidil hydrochloride [64887-14-5]; Down 200; 9.4uM; MCF7; HT_HG-U133A

TNK1 ARC ALOX15 VCPIP1 SLC37A1 HTR1E CTC1 NDST2 ARHGEF26

4.50e-0519719196455_DN
DrugPractolol [6673-35-4]; Up 200; 15uM; PC3; HT_HG-U133A

TNK1 GNMT RS1 HEPH SCNN1A ARC PLXNC1 ZNF277 IHH

4.68e-0519819194603_UP
DrugVi-o

NOS1 NOS2 NOS3

4.70e-0591913CID005289554
Drug8-OH-DPAT

ADCY9 NOS1 NOS2 NOS3 ADCY4 HTR1E IDE

5.97e-051171917CID000001220
DrugSeptide

NOS1 NOS2 NOS3 IDE

6.21e-05261914CID000119137
Drug2 pN

NAT1 ADCY9 KL MGAM ADCY4 PPA1

6.65e-05821916CID000122874
Drugbaicalein

KL NOS1 NOS2 NOS3 ALOX15 MGAM PDCD6 MAPK15

6.96e-051621918CID005281605
Drugnsc25485

SLC24A3 ADCY9 PKD1 SCNN1A NOS2 MGAM ADCY4 IDS SLC9A5 MAPK15 ATP12A

6.96e-0531219111CID000004605
DrugL-N(Omega)-Nitroarginine-2,4-L-Diaminobutyric Amide

NOS1 NOS3

7.00e-0521912DB01821
Drugcalcium citrate

F8 MGAM

7.00e-0521912CID000013136
DrugN,N-dimethylarginine

NOS2 NOS3

7.00e-0521912DB01686
Drug4-iodoaniline

NAT1 NAT2

7.00e-0521912ctd:C013067
Drug6 Ni

NOS2 NOS3

7.00e-0521912CID000024239
DrugN-Omega-Propyl-L-Arginine

NOS1 NOS2

7.00e-0521912DB02644
DrugS-Ethyl-N-Phenyl-Isothiourea

NOS1 NOS3

7.00e-0521912DB03707
DrugN-hydroxy-2-aminofluorene

NAT1 NAT2

7.00e-0521912ctd:C001368
Drugdimagnesium silicate

BMP1 MGAM

7.00e-0521912CID000066225
DrugN-{(3S,4S)-4-[(6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL]PYRROLIDIN-3-YL}-N'-(4-CHLOROBENZYL)ETHANE-1,2-DIAMINE

NOS1 NOS3

7.00e-0521912DB08018
DrugN-{(3R,4S)-4-[(6-amino-4-methylpyridin-2-yl)methyl]pyrrolidin-3-yl}-N'-(3-chlorobenzyl)ethane-1,2-diamine

NOS1 NOS3

7.00e-0521912DB08019
Drug3 h x

NOS2 NOS3

7.00e-0521912CID016058621
DrugDB02077

NOS2 NOS3

7.00e-0521912CID000656912
DrugAC1LCVOW

NOS2 NOS3

7.00e-0521912CID000656910
Drug5-nitroindazole

NOS2 NOS3

7.00e-0521912CID000021501
Drug4-bromoaniline

NAT1 NAT2

7.00e-0521912ctd:C023621
DrugAC1NRAON

NOS2 NOS3

7.00e-0521912CID005288020
DrugDB07388

NOS2 NOS3

7.00e-0521912CID011149707
Drugbromoacetanilide

NAT1 NAT2

7.00e-0521912ctd:C056005
DrugAC1L96OZ

NOS2 NOS3

7.00e-0521912CID000439092
DrugAC1NRAUH

NOS2 NOS3

7.00e-0521912CID005288100
DrugETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE

NOS2 NOS3

7.00e-0521912DB07388
DrugNSC-10379

NOS2 NOS3

7.00e-0521912CID000223131
Drughard metal

NOS2 NOS3

7.00e-0521912ctd:C080121
Drug2-(bromoacetylamino)fluorene

NAT1 NAT2

7.00e-0521912ctd:C075748
DrugEthylisothiourea

NOS2 NOS3

7.00e-0521912DB02234
Drug7-Nitroindazole

NOS2 NOS3

7.00e-0521912DB02207
DrugL-N(Omega)-Nitroarginine-(4r)-Amino-L-Proline Amide

NOS1 NOS3

7.00e-0521912DB02077
DrugN-(4-(2-((3-Chlorophenylmethyl)Amino)Ethyl)Phenyl)-2-Thiophecarboxamidine

NOS1 NOS2

7.00e-0521912DB03449
DrugN-{(4s)-4-Amino-5-[(2-Aminoethyl)Amino]Pentyl}-N'-Nitroguanidine

NOS1 NOS3

7.00e-0521912DB02027
Drug5-Nitroindazole

NOS2 NOS3

7.00e-0521912DB04534
Drug6-Nitroindazole

NOS2 NOS3

7.00e-0521912DB03100
DrugNitroarginine

NOS1 NOS3

7.00e-0521912DB04223
DrugThioglycolates

NOS1 NOS2 NOS3 GPR68

7.24e-05271914ctd:D013864
Drugguanidinoglutaric acid

NOS1 NOS2 NOS3

9.13e-05111913CID000002105
Drugcetraxate

NOS1 NOS2 NOS3

9.13e-05111913CID000002680
DrugTBPS

GABRG2 CLIC2 HTR1E CLIC4 TFR2 CRYGD

9.26e-05871916CID000104781
Drugisoquercitrin

PHEX NOS2 IDE GBA2

9.67e-05291914CID005280804
Drugglibenclamide

ZMPSTE24 ABCA7 ADCY9 CLIC2 NOS1 NOS2 NOS3 MGAM ADCY4 CLIC4 IDE G6PC3

9.82e-0538219112CID000003488
Drugpotassium

GABRG2 KCNH7 SPEF2 SLC24A3 ADCY9 ITIH3 GGT1 CLIC2 PKD1 SCNN1A CACNA1H NOS1 NOS2 NOS3 MGAM ADCY4 TPCN2 CLIC4 CRYGD SLC9A5 ATP12A

1.19e-04100819121CID000000813
DrugL-Citrulline

NOS1 NOS2 NOS3

1.21e-04121913DB00155
Drugthaliporphine

NOS1 NOS2 NOS3

1.21e-04121913CID000100020
DrugTMB-8

ADCY9 CACNA1H NOS1 NOS2 NOS3 ALOX15 ADCY4 ANPEP

1.24e-041761918CID000005494
Drugmolsidomine

KL SGSM3 NOS1 NOS2 NOS3

1.26e-04581915CID000004238
Drugdeuteroporphyrin

NOS1 NOS2 NOS3 MGAM

1.26e-04311914CID000067973
Drugmg X

AOC1 NOS1 NOS2 NOS3

1.26e-04311914CID000010111
DrugPeroxynitrous Acid

NAT1 NAT2 NOS2 NOS3 NOA1

1.37e-04591915ctd:D030421
DrugRU 24969

ADCY9 GP1BA ADCY4 IDE

1.44e-04321914CID000108028
Druglanthanum

ADCY9 PKD1 CACNA1H MGAM ADCY4 TPCN2 MAPK15

1.54e-041361917CID000023926
Drugaminoguanidine hydrochloride

NOS1 NOS2 NOS3

1.56e-04131913CID000016017
DrugNitrates

SCNN1A NOS2 NOS3

1.56e-04131913ctd:D009566
Drugiohexol

ADCY9 GGT1 ADCY4 ANPEP IDE

1.60e-04611915CID000003730
Drugzonisamide

SCNN1A CACNA1H NOS1 NOS2 NOS3

1.73e-04621915CID000005734
Drugdl-ornithine

AOC1 GGT1 NOS1 NOS2 NOS3 SLC25A12 G6PC3 ATP12A

1.95e-041881918CID000000389
DrugNG-amino-L-arginine

NOS1 NOS2 NOS3

1.98e-04141913CID000124357
DrugAniline Compounds

NAT1 NAT2 GGT1

1.98e-04141913ctd:D000814
DrugGEA 3162

NOS1 NOS2 NOS3

1.98e-04141913CID003035443
DrugT6-7

NOS1 NOS2 NOS3

1.98e-04141913CID000216324
Diseaseepilepsy (implicated_via_orthology)

GABRG2 SCN11A KCNH7 NFASC SLC24A3 LRP1B NOS1 NOS2 NOS3 KCNT1 LRP1 ATP12A

7.92e-1016319112DOID:1826 (implicated_via_orthology)
Diseaseautism spectrum disorder (is_marker_for)

SHH SLC25A12 IHH

9.17e-0671913DOID:0060041 (is_marker_for)
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT1 GGTLC3 GGT2P

9.17e-0671913DOID:5022 (biomarker_via_orthology)
Diseaseend stage renal disease (biomarker_via_orthology)

NAT1 NAT2 KL NOS1 NOS3

1.33e-05471915DOID:783 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT1 GGTLC3 GGT2P

1.46e-0581913DOID:0050741 (biomarker_via_orthology)
Diseaseoccupational dermatitis (is_implicated_in)

NAT1 NAT2

4.17e-0521912DOID:4404 (is_implicated_in)
DiseaseParkinson Disease, Secondary Vascular

NOS2 SHH ATP13A2

5.63e-05121913C0751414
DiseaseAtherosclerotic Parkinsonism

NOS2 SHH ATP13A2

5.63e-05121913C0751415
DiseaseSecondary Parkinson Disease

NOS2 SHH ATP13A2

5.63e-05121913C0030569
DiseaseN-acetylputrescine measurement

NAT1 NAT2 AOC1

5.63e-05121913EFO_0800127
Diseasehepatic encephalopathy (biomarker_via_orthology)

GABRG2 NOS1 NOS2

1.15e-04151913DOID:13413 (biomarker_via_orthology)
DiseaseIron-Refractory Iron Deficiency Anemia

TMPRSS6 LPIN2

1.25e-0431912C0085576
DiseaseIntestinal Perforation

NOS1 NOS3

1.25e-0431912C0021845
DiseaseExudative retinopathy

CTC1 CRB1

2.48e-0441912C0154832
Diseasepulmonary edema (biomarker_via_orthology)

NOS2 NOS3

2.48e-0441912DOID:11396 (biomarker_via_orthology)
Diseasediabetic angiopathy (biomarker_via_orthology)

NOS2 NOS3

2.48e-0441912DOID:11713 (biomarker_via_orthology)
Diseaseimpotence (biomarker_via_orthology)

NOS1 NOS2 NOS3

3.76e-04221913DOID:1875 (biomarker_via_orthology)
Diseaserenal hypertension (implicated_via_orthology)

NOS2 NOS3

4.12e-0451912DOID:1073 (implicated_via_orthology)
Diseaselactosyl-N-palmitoyl-sphingosine (d18:1/16:0) measurement

ABCA7 GSDMA

4.12e-0451912EFO_0800429
DiseasePolycystic Kidney - body part

MKS1 PKD1

4.12e-0451912C1567435
DiseaseArteriosclerosis

KL NOS3

4.12e-0451912C0003850
DiseaseEtat Marbre

ATXN7 TSEN34 ARC

4.30e-04231913C0266487
DiseaseVision Disability

ATXN7 TSEN34

6.15e-0461912C3489704
DiseaseMetamorphopsia

ATXN7 TSEN34

6.15e-0461912C0271185
DiseaseMicropsia

ATXN7 TSEN34

6.15e-0461912C0233769
DiseaseMacropsia

ATXN7 TSEN34

6.15e-0461912C0233771
DiseaseEPILEPSY, CHILDHOOD ABSENCE, 1

GABRG2 CACNA1H

6.15e-0461912C1838604
DiseaseVision Disorders

ATXN7 TSEN34

6.15e-0461912C0042790
DiseaseHemeralopia

ATXN7 TSEN34

6.15e-0461912C0018975
Diseaseallergic contact dermatitis (is_implicated_in)

NAT1 NAT2

6.15e-0461912DOID:3042 (is_implicated_in)
Diseaselissencephaly (implicated_via_orthology)

NOS1 NOS2 NOS3

6.96e-04271913DOID:0050453 (implicated_via_orthology)
DiseaseProstatic Neoplasms

NAT1 NAT2 STARD10 GNMT LRP1B GGT1 NOS3 PPFIBP2 NDST2 CLIC4 CTBP2 SPEN

7.23e-0461619112C0033578
DiseaseMalignant neoplasm of prostate

NAT1 NAT2 STARD10 GNMT LRP1B GGT1 NOS3 PPFIBP2 NDST2 CLIC4 CTBP2 SPEN

7.23e-0461619112C0376358
Diseasechronic kidney disease (biomarker_via_orthology)

KL NOS3 SHH

7.76e-04281913DOID:784 (biomarker_via_orthology)
DiseaseVisual Impairment

ATXN7 TSEN34

8.57e-0471912C3665347
Diseaseretinopathy of prematurity (is_implicated_in)

NOS3 IHH

8.57e-0471912DOID:13025 (is_implicated_in)
DiseaseMASA syndrome (implicated_via_orthology)

NFASC TRPM3

8.57e-0471912DOID:0060246 (implicated_via_orthology)
DiseaseMovement Disorders

ATXN7 TSEN34 ARC

8.62e-04291913C0026650
Diseasevenous thromboembolism, fibrinogen measurement

TSPAN15 HGFAC DCHS2 JMJD1C

9.48e-04671914EFO_0004286, EFO_0004623
DiseaseNeural Tube Defects

NAT2 PTK7 VANGL2

9.53e-04301913C0027794
Diseaseasthma, cardiovascular disease

P4HA2 RAD50 GSDMA

9.53e-04301913EFO_0000319, MONDO_0004979
DiseaseMyopia

SCN11A NFASC SLC24A3 NKAIN2 MEI4 TRPM3 TRHDE SLC25A12 RASGEF1B

9.60e-043851919HP_0000545
DiseaseFEV/FEC ratio

BNC2 DCHS2 VPS13C SPEF2 STARD10 ETV6 SLC24A3 SCAPER MMP15 SMURF2 MGAM SHH MTFP1 ATP13A2 JMJD1C SKAP1 LRP1 ARHGEF26

1.09e-03122819118EFO_0004713
Diseasefocal segmental glomerulosclerosis (is_marker_for)

TMEM63C SHH

1.14e-0381912DOID:1312 (is_marker_for)
Diseasechildhood absence epilepsy (is_implicated_in)

GABRG2 CACNA1H

1.14e-0381912DOID:1825 (is_implicated_in)
DiseaseAlzheimer disease

ABCA7 NOS3

1.14e-0381912cv:C0002395
Diseaseneuroblastoma (is_marker_for)

SCNN1A MTFP1

1.14e-0381912DOID:769 (is_marker_for)
DiseaseIndustrial Dermatosis

NAT1 NAT2

1.14e-0381912C0086457
DiseaseDermatitis, Occupational

NAT1 NAT2

1.14e-0381912C0028796
Diseaseprogeria (implicated_via_orthology)

ZMPSTE24 VCPIP1

1.14e-0381912DOID:3911 (implicated_via_orthology)
Diseasecystatin C measurement

BNC2 ACSS1 DCST1 TPCN2 SHH CLIC4 CRB1 LRP1 ARHGEF26

1.30e-034021919EFO_0004617
Diseasetriglyceride measurement, physical activity

NAT2 HGFAC JMJD1C

1.38e-03341913EFO_0003940, EFO_0004530
Diseaseadvanced glycation end-product measurement

NAT2 MMP27

1.46e-0391912EFO_0007819
Diseaseprimary bacterial infectious disease (implicated_via_orthology)

SHH IHH

1.46e-0391912DOID:0050338 (implicated_via_orthology)
Disease5-acetylamino-6-formylamino-3-methyluracil measurement

NAT1 NAT2

1.46e-0391912EFO_0800950
DiseaseHepatic Insufficiency

NOS2 NOS3

1.46e-0391912C1306571
Diseaseneural tube defect (implicated_via_orthology)

VANGL2 LRP6

1.46e-0391912DOID:0080074 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

HGFAC BNC2 AOC1 SLC24A3 PTK7 TRPM3 ALOX15 TPCN2 SHH CRB1 PLXNC1 LRP1

1.48e-0367019112EFO_0006335, EFO_0006336
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

NKAIN2 LRP1B TRPM3 FA2H

1.52e-03761914EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
DiseaseHypertensive disease

AOC1 SCNN1A NOS2 NOS3 ALOX15 GP1BA

1.53e-031901916C0020538
Diseasevery low density lipoprotein particle size measurement

NAT2 HGFAC ITIH3 JMJD1C TYW1B

1.78e-031331915EFO_0008594
DiseaseAllodynia

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C0458247
DiseaseMechanical Allodynia

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C2936719
DiseaseHyperalgesia, Secondary

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C0751212
DiseaseHyperalgesia, Primary

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C0751211
DiseaseHyperalgesia, Thermal

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C0751214
DiseaseTactile Allodynia

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C0751213
DiseaseHyperalgesia

SCN11A CACNA1H NOS1 NOS2

2.19e-03841914C0020429
Diseaselignoceroylcarnitine (C24) measurement

TPCN2 WWP1

2.21e-03111912EFO_0800541
Disease5-acetylamino-6-amino-3-methyluracil measurement

NAT1 NAT2

2.21e-03111912EFO_0800951
Diseasesexual dimorphism measurement

TMEM250 AOC1 ETV6 DCST1 ADCY9 MEI4 MMP24 PKD1 MGAM P4HA2 ADCY4 PDCD6 ATP13A2 JMJD1C G6PC3 RASGEF1B

2.35e-03110619116EFO_0021796
DiseaseSclerocystic Ovaries

ASPM SCNN1A ARHGAP23 SPTBN4 CDH15

2.51e-031441915C1136382
DiseasePolycystic Ovary Syndrome

ASPM SCNN1A ARHGAP23 SPTBN4 CDH15

2.51e-031441915C0032460
Diseasecolitis (biomarker_via_orthology)

NOS2 NOS3 TLR3

2.55e-03421913DOID:0060180 (biomarker_via_orthology)
DiseaseCooley's anemia

CACNA1H TFR2

2.64e-03121912C0002875
DiseasePathological accumulation of air in tissues

KL NOS2

2.64e-03121912C0013990
DiseaseThalassemia Intermedia

CACNA1H TFR2

2.64e-03121912C0271979
Diseaseiron biomarker measurement, serum iron measurement

TMPRSS6 TFR2

2.64e-03121912EFO_0004461, EFO_0006332
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

GABRG2 SCN11A

2.64e-03121912DOID:0060170 (implicated_via_orthology)
Diseaseretinopathy of prematurity (biomarker_via_orthology)

NOS1 NOS2

2.64e-03121912DOID:13025 (biomarker_via_orthology)
Diseasetryptophan betaine measurement

P4HA2 RAD50

2.64e-03121912EFO_0021017
DiseaseEssential Hypertension

NOS2 NOS3

2.64e-03121912C0085580
DiseaseThalassemia Minor

CACNA1H TFR2

2.64e-03121912C0085578
DiseasePrecursor B-Cell Lymphoblastic Leukemia-Lymphoma

ETV6 CRLF2

2.64e-03121912C0023485
Diseasebeta Thalassemia

CACNA1H TFR2

2.64e-03121912C0005283
DiseaseDisorder of eye

RS1 MKS1 ARL13B PLA2G5 ATP13A2 CRB1

2.66e-032121916C0015397
Diseasematrix metalloproteinase measurement

MMP27 SLC24A3

3.10e-03131912EFO_0004744
DiseaseNeurodegeneration with brain iron accumulation

FA2H ATP13A2

3.10e-03131912cv:C2931845
Diseasecardiomyopathy (biomarker_via_orthology)

NOS1 NOS3

3.10e-03131912DOID:0050700 (biomarker_via_orthology)
Diseaseliver cirrhosis (implicated_via_orthology)

NOS3 RAD50

3.10e-03131912DOID:5082 (implicated_via_orthology)
DiseaseFulminant Hepatic Failure with Cerebral Edema

GABRG2 NOS1

3.10e-03131912C0751197
DiseaseHepatic Stupor

GABRG2 NOS1

3.10e-03131912C0751198
DiseaseHepatic Encephalopathy

GABRG2 NOS1

3.10e-03131912C0019151
DiseaseHepatic Coma

GABRG2 NOS1

3.10e-03131912C0019147
Diseaseleukemia (is_implicated_in)

NAT2 ETV6

3.10e-03131912DOID:1240 (is_implicated_in)
Diseasecortisol measurement, response to corticosteroid, response to synacthen

LRP1B NOS1

3.10e-03131912EFO_0005843, EFO_0009175, GO_0031960
DiseaseSalivary Gland Neoplasms

SLC24A3 ASPM SPEN

3.51e-03471913C0036095
Diseaseiron biomarker measurement, transferrin saturation measurement

TMPRSS6 TFR2

3.60e-03141912EFO_0004461, EFO_0006333
Diseasebiliary atresia (is_marker_for)

GGT1 SHH

3.60e-03141912DOID:13608 (is_marker_for)
DiseaseManganese Poisoning

NOS2 ATP13A2

3.60e-03141912C0677050

Protein segments in the cluster

PeptideGeneStartEntry
YWLFYGVRILDARER

VANGL2

196

Q9ULK5
TGYFRVNYDLRNWRL

TRHDE

686

Q9UKU6
VSFVEEYRWLAYVLL

TTYH1

206

Q9H313
NGFWYLDQIRREQYI

NAT1

156

P18440
EIWYLLEGSYRVYQL

CATSPERG

536

Q6ZRH7
FGQYRRTWFYITIIE

DENND10P1

61

Q6NSW5
RYWETVERLKINQFY

ACSS1

371

Q9NUB1
GIWRYLTNAYSRDEF

CLIC4

216

Q9Y696
YRRNTWLYQALREGT

CTBP2

146

P56545
QAYGASLYEQLVWER

CTC1

446

Q2NKJ3
WTLRDYVRGYILQDA

BNC2

211

Q6ZN30
LSVCTQWYRFAEIRY

CCAR1

536

Q8IX12
FLWRKRDLYQTLYVD

ARC

301

Q7LC44
DQTVFLQRRYWSNYV

CALHM3

206

Q86XJ0
TLFWGARYVRTDYTL

GSDMA

46

Q96QA5
IALDRYWAITNAIEY

HTR1E

116

P28566
RIAGDYVSEEVWYRV

AP2A1

451

O95782
LARQNEYYCRLDFLW

ADCY4

806

Q8NFM4
VLIYQRVSDGWYEGE

ARHGEF26

816

Q96DR7
IRIRGIWKNYYAESY

ARL13B

76

Q3SXY8
VTGYYRVNYDEENWR

ANPEP

626

P15144
VVWAIGEYLSVTYDR

AP5Z1

646

O43299
GLYSSVAIWYARLQE

ADCY10

1421

Q96PN6
QRRSWLIIQRYVEGY

AOC1

196

P19801
RSRLCWYDYVEVRDG

BMP1

371

P13497
LLVYVRYVWQDDFVE

FAM200A

156

Q8TCP9
YRASAIIIQRWYRGI

ASPM

2066

Q8IZT6
LRYVWGGFVYLQDLV

ABCA7

496

Q8IZY2
IAGDYVSEEVWYRVI

AP2A2

451

O94973
YYEEWAERRLQASLA

ATP8B2

626

P98198
WRSTYRGQDIEYIEI

RAD50

1151

Q92878
RVYLEGEFVEWLRRY

HLA-H

181

P01893
RRYFGEKVALYFAWL

ANO7

336

Q6IWH7
DFRVWNAQLIRYAGY

NOS2

256

P35228
YQLLSDSRYENFIRW

ETV6

346

P41212
FKGERYWRYSEERRA

MMP24

491

Q9Y5R2
RHLWRIYYDITDVEF

MMP27

301

Q9H306
ADAYRAQILRIQYAW

FIGNL1

31

Q6PIW4
LLYWTDVVEDRIYRG

LRP1B

1301

Q9NZR2
RLLSVEFVWQRYLDY

MAGEE1

626

Q9HCI5
EFVWQRYLDYRPVTD

MAGEE1

631

Q9HCI5
WEERQDILGRTYYVN

NEDD4

616

P46934
RAVGFEARYVWDYTD

NGLY1

321

Q96IV0
IETLRFAYNYIWALA

NEUROG1

131

Q92886
VYDREVQWTLGAILY

ENTPD7

506

Q9NQZ7
LRWAAYAAAEVLQVY

NFKBID

61

Q8NI38
LRQRLEEYFQHAWTY

KCNH7

696

Q9NS40
DQAVTEYVATRWYRA

MAPK15

171

Q8TD08
GRLYWVDAFYDRIET

LRP1

711

Q07954
FWTEYRSGSVYRLER

LRP1

756

Q07954
SYGQEWTRYQREYLE

ATP12A

916

P54707
ARWYDYYTGVDINAR

MGAM

2576

O43451
GYRVRVYRQDSATQW

JMJD1C

191

Q15652
DRYWLFREANLEPGY

MMP15

436

P51511
AYYASRRVGIAVLWI

G6PC3

46

Q9BUM1
IYLSYKGNIWEQIFR

KCNT1

176

Q5JUK3
WVALRQVDGVYYNLD

JOSD2

126

Q8TAC2
FLRWLFDIYYLEQAS

TMEM63C

516

Q9P1W3
WREQFYRYYQVARDV

FBXW5

46

Q969U6
RRYDTDQDGWIQVSY

PDCD6

166

O75340
RNNRWYLAVAATYVL

PLXNC1

171

O60486
LYLANWIRRYQTENF

KDELR3

161

O43731
WIRRYQTENFYDQIA

KDELR3

166

O43731
ESGYSWRVILLRNYQ

FBXO48

96

Q5FWF7
VLERQIFDFLGYQWA

NKAIN2

21

Q5VXU1
YYLGEGEASRRWLQQ

HEXD

151

Q8WVB3
AQDALRLWEIIYRYV

ALOX15

461

P16050
EGYIYWTDDEVRAIR

LRP6

371

O75581
RDLYRDTWVRYLGYA

MTFP1

11

Q9UDX5
TRRYYLGAVELSWDY

F8

21

P00451
QYADGEAARVWQLYI

GNMT

21

Q14749
WQLYIGDTRSRTAEY

GNMT

31

Q14749
LLYEVQYRSPFDTEW

CRLF2

146

Q9HC73
LFRDEHYIGIYVDIW

NIM1K

241

Q8IY84
EAYVEWFNRLSYLVA

RASGEF1B

256

Q0VAM2
YTRVANYVDWINDRI

HGFAC

631

Q04756
SRQIGRGYYVFDSRW

ATXN7

526

O15265
WALQTLAVDYGSYIR

SLC24A3

561

Q9HC58
WLEDFGLAQYVIFAR

PPFIBP2

566

Q8ND30
GYREAREQHWRYYTL

MAB21L3

81

Q8N8X9
LNIIRVYAGWKDFIY

MAGEA13P

221

A6NCF6
ERIGYSNEWYLNRLR

OR5AS1

306

Q8N127
ETVVRVYPANERFWY

RABGAP1L

411

Q5R372
IIYNLWFGYDVKRAV

GGTLC3

141

B5MD39
DFRVWNSQLIRYAGY

NOS1

476

P29475
FRIWNSQLVRYAGYR

NOS3

241

P29474
WYNLLRSGEGDYRTR

P4HA2

486

O15460
WIYLRRQFDYESTQT

DCHS2

1141

Q6V1P9
IRTQSYKYRFAWGVV

PLA2G5

81

P39877
ANARRWLEQYYVGEL

FA2H

71

Q7L5A8
GQLREYRAYYWRESS

NFASC

856

O94856
ALLQETAYERLYRWA

COG6

216

Q9Y2V7
AGIRFIISFSRDQWY

SLC37A1

6

P57057
RVLRYYLFQGQRYIW

ATP13A2

161

Q9NQ11
VLEGSWVLYELSNYR

CRYGD

126

P07320
WVLYELSNYRGRQYL

CRYGD

131

P07320
FIEIDRWEQEYLYHR

DNAH6

251

Q9C0G6
ETVESFDWQRQLRYY

DNAH6

1401

Q9C0G6
RIQETCGDWYRGYLI

DOCK2

36

Q92608
RGQEAYERLLWNGRY

GBA2

721

Q9HCG7
DYVYRQEARLEWALG

DCST1

361

Q5T197
LYGQLLWREFFYTAA

CRY1

286

Q16526
YTIDIFFAQTWYDRR

GABRG2

111

P18507
TRSVRSQEDQWYLGY

CCDC144B

26

Q3MJ40
LLVWFLNREFEVSYR

ADCY9

991

O60503
YFRRWLQDNAENVYV

GP1BA

231

P07359
FTLREVQERWYALLY

MCRS1

166

Q96EZ8
GYLEATVDWFRRYKV

PPA1

181

Q15181
RGIWYLDQIRREQYI

NAT2

156

P11245
LYFVNLRTRDETYIW

KLHDC1

96

Q8N7A1
FEWQDAYTIRRGLFY

KLB

466

Q86Z14
WHRGYSIRRGLFYVD

KL

466

Q9UEF7
SEEGRLYYDGEWYIR

BRMS1L

256

Q5PSV4
YREVQLPDRGWFVYQ

IDE

766

P14735
SIRTIDYRYTVWVGF

IDS

491

P22304
ENSTYQYIRVWLERG

CRB1

756

P82279
VPRVRNLVEADYSYW

COLGALT1

481

Q8NBJ5
RRIAARYWDIMEYFD

HHIPL2

76

Q6UWX4
GLYQWDFASYDILRV

FBXW2

346

Q9UKT8
YLWETFLAQRQRRIY

ZMPSTE24

31

O75844
YLGDTWNRLDFFIVV

CACNA1H

166

O95180
FGQYRRTWFYITTIE

DENND10

61

Q8TCE6
IAQYALLGYFIRSWR

SLC22A15

211

Q8IZD6
DYVEIWQAYLDYLRR

SART3

416

Q15020
WQAYLDYLRRRVDFK

SART3

421

Q15020
DAVREWYRFHYINIL

SCNN1A

246

P37088
RYWAFLFDNLRRAVD

SCAPER

101

Q9BY12
QDYDYLRDWGPRFAR

CDH15

761

P55291
LQRSWRYRGDVYLVG

NOA1

331

Q8NC60
GVWRYLHNAYAREEF

CLIC2

211

O15247
LARLAVEAGFDWVYY

IHH

166

Q14623
NRVTVYEYDIRGDQW

KBTBD6

581

Q86V97
IYNLWFGYDVKRAVE

GGT2P

486

P36268
VQRGSRVAYAWYFSL

PKD1

1996

P98161
WQRAINYYRFLVGFL

GPR68

181

Q15743
WLLIYTRRNYEAANS

PIWIL1

496

Q96J94
DVSRYENIFYLFWVL

MEI4

306

A8MW99
RFQDTKRLLQDYYWG

SPEF2

1161

Q9C093
YIRIKDDEWNIYRRY

SNX29

681

Q8TEQ0
LARLAVEAGFDWVYY

SHH

161

Q15465
ARLTVNADVGYYSWR

STARD10

106

Q9Y365
IRERWFQNYGEYLDI

RSAD2

161

Q8WXG1
SEYLLARDEFYRWFQ

SYNE3

116

Q6ZMZ3
RSGLTEVYQWYLDLR

NARS2

421

Q96I59
EVYQWYLDLRRFGSV

NARS2

426

Q96I59
RDYIFGNYIERLWAY

ITIH3

546

Q06033
RVYYLGIRDVQWNYA

HEPH

26

Q9BQS7
QYVYRRIWEETGNYT

SLC46A3

26

Q7Z3Q1
RIWDLFFYEGSRVLF

SGSM3

296

Q96HU1
YLVNVSRYWLSLGVR

ST8SIA5

281

O15466
LALEVVRFFYDFLWR

SHCBP1L

251

Q9BZQ2
SAYRIRDQIWDVYYR

SLC9A5

516

Q14940
EVFWRNYFYRVSLIK

SYAP1

196

Q96A49
QRWFVLRGDQLFYYK

ARHGAP22

56

Q7Z5H3
GFTTRYRIYREFARW

BRINP2

81

Q9C0B6
YRIYREFARWKVNNL

BRINP2

86

Q9C0B6
QYYIRAVSDRWLGAE

ASCC3

1266

Q8N3C0
VTYELLQRWFYIDFG

SLC25A12

596

O75746
TWVLARREADGFYYR

C11orf16

86

Q9NQ32
RFWDLAYPERSYVVA

PIK3R4

1266

Q99570
YVRLYVNWRFLRGIE

SMURF2

581

Q9HAU4
ERERTYNKSGRWFYL

ZFP28

371

Q8NHY6
TTFLVILWLYFYRGN

TRAV10

6

A0A0B4J240
EWRGLENIFEIYLSY

TLR3

451

O15455
YGFWVIRLRKGNEYR

TRIM68

391

Q6AZZ1
YLREQEVSERWFRYN

ZBTB37

356

Q5TC79
YTVSGLRGLFWYRQD

TRAV20

46

A0A0B4J274
VLSLDFWQRYRVEGY

MKS1

401

Q9NXB0
FWQRYRVEGYGAVVL

MKS1

406

Q9NXB0
PARGREFYSEWETYQ

SPEN

651

Q96T58
IGSSERYQRWLQYKF

RLF

541

Q13129
YSIYRDLWERGFFLS

TSEN34

221

Q9BSV6
FDVYIKTRWLYGFIR

TMEM250

41

H0YL14
RSDGRVIYCVNIIYW

TRPM3

991

Q9HCF6
FSDIRREGWLYYKQI

ARHGAP23

686

Q9P227
GQLWAYTERAVFRYH

VPS18

376

Q9P253
FGLLSSWVYLRFYQR

TMEM115

196

Q12893
SEQVRYCARFSYLWL

TSPAN15

6

O95858
ELFWYVQYSRQRLQL

TRAV16

51

A0A0A6YYK6
AWSRELLDRYCVEYG

NDST2

151

P52849
RFQYRWLEFSRVIQG

PHEX

381

P78562
GEERRVALEQQYWLY

SPTBN4

1716

Q9H254
LFRGAEYRRYTWVTG

ST7L

161

Q8TDW4
LLGVVWYFRINYRQF

TMUB2

281

Q71RG4
EIRYQFYKRDQLIWS

VPS13C

3386

Q709C8
IFSWGVLASLAYQRY

SYNGR2

156

O43760
RVVRETVYWFQYESD

VCPIP1

601

Q96JH7
IWRRIFQSSYIREQY

VWA5B2

651

Q8N398
FQRYILYWRKRFTEQ

ZNF277

96

Q9NRM2
YQWDLSAASRYVLAR

TNK1

651

Q13470
YFRRGWNIFDSIVAL

SCN11A

636

Q9UI33
IEIFRIGYEHWAIYV

PLAAT5

136

Q96KN8
SLWINRFYIYLGFAV

TYW1

16

Q9NV66
GWEIRYTREGVRYFV

WWP1

501

Q9H0M0
YSVQYRTDERLNWIY

RS1

151

O15537
LRINSVEVYDGTWYR

PTK7

466

Q13308
LQWVYSARGDYIRAA

TFR2

671

Q9UP52
YEYLIRLFQEWEAHR

TCF25

396

Q9BQ70
ILRGFQQIKARYYWD

SKAP1

41

Q86WV1
VVNNWQVFLDAYRRY

TPCN2

651

Q8NHX9
SLWINRFYIYLGFAV

TYW1B

16

Q6NUM6
DYGLALWFDAYALRR

TMPRSS6

376

Q8IU80
IYNLWFGYDVKRAVE

GGT1

486

P19440
VIRIYNRYYNWALAA

LPIN2

511

Q92539
LSIYDNWIRYFNRSS

NAALADL1

481

Q9UQQ1
IYRQVLRGVWSGEYS

MYO7B

1306

Q6PIF6