Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH5 DNAH9 DNAH11

1.81e-05181814GO:0008569
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH14 KIF28P DYNC1LI1 DNAH5 DNAH9 DNAH11

4.14e-05701816GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO18A DNAH14 KIF28P DYNC1LI1 DNAH5 DNAH9 DNAH11

1.01e-041181817GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH14 DNAH5 DNAH9 DNAH11

1.13e-04281814GO:0051959
GeneOntologyMolecularFunctionacyltransferase activity

CUL2 NAA15 RMND5A MARCHF6 HECTD4 RNF213 C10orf90 HUWE1 HHATL IFNB1 ZDHHC20 ZDHHC15 FASN UBR5 CCNB1IP1 HERC5 PLAAT5 NAA16

2.49e-0477518118GO:0016746
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH14 DNAH5 DNAH9 DNAH11

3.41e-04371814GO:0045505
GeneOntologyMolecularFunctionprocollagen galactosyltransferase activity

COLGALT2 COLGALT1

4.84e-0441812GO:0050211
GeneOntologyCellularComponent9+0 motile cilium

ODAD4 DNAH5 DNAH11

1.32e-0561843GO:0097728
GeneOntologyCellularComponentmicrotubule associated complex

EML2 DNAH14 AURKA KIF28P DYNC1LI1 DNAH5 DNAH9 DNAH11

9.24e-051611848GO:0005875
GeneOntologyCellularComponentdynein complex

DNAH14 DYNC1LI1 DNAH5 DNAH9 DNAH11

1.12e-04541845GO:0030286
GeneOntologyCellularComponentcondensed chromosome

SLF1 TOPBP1 CKAP5 TEX11 AURKA KMT5B DYNC1LI1 MTBP CCNB1IP1 STAG3

4.07e-0430718410GO:0000793
GeneOntologyCellularComponentBRCA1-B complex

BRIP1 TOPBP1

4.57e-0441842GO:0070532
GeneOntologyCellularComponentgerm cell nucleus

KDM3A TOPBP1 H1-9P AURKA SCMH1 STAG3

4.97e-041131846GO:0043073
GeneOntologyCellularComponentNatA complex

NAA15 NAA16

7.57e-0451842GO:0031415
GeneOntologyCellularComponentmicrotubule

CKAP5 EML2 DNAH14 AURKA EML5 KIF28P DYNC1LI1 MACF1 CLMP DNAH5 DNAH9 WDR44 DNAH11

9.13e-0453318413GO:0005874
GeneOntologyCellularComponentmale germ cell nucleus

KDM3A TOPBP1 H1-9P SCMH1 STAG3

9.80e-04861845GO:0001673
GeneOntologyCellularComponentmotile cilium

ODAD4 DNAH14 WDR19 AKAP4 DAW1 PKD1 DNAH5 CFAP69 DNAH9 DNAH11

1.24e-0335518410GO:0031514
GeneOntologyCellularComponentchromosomal region

SLF1 ACD FLYWCH1 CKAP5 THOC2 MEN1 AURKA KMT5B DYNC1LI1 MTBP STAG3

1.31e-0342118411GO:0098687
MousePhenomulti-headed sperm

GMCL1 GMCL2 PRSS50

1.29e-0551543MP:0031408
DomainWD40_repeat_dom

FBXW10B FBXW10 AHI1 DCAF4L2 COPA TAF1C EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

7.24e-0629718213IPR017986
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH5 DNAH9 DNAH11

8.09e-06141824IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH5 DNAH9 DNAH11

8.09e-06141824IPR024743
DomainMT

DNAH14 DNAH5 DNAH9 DNAH11

8.09e-06141824PF12777
DomainAAA_8

DNAH14 DNAH5 DNAH9 DNAH11

8.09e-06141824PF12780
DomainWD40

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

9.28e-0625918212PF00400
DomainDHC_fam

DNAH14 DNAH5 DNAH9 DNAH11

1.09e-05151824IPR026983
DomainDynein_heavy

DNAH14 DNAH5 DNAH9 DNAH11

1.09e-05151824PF03028
DomainDynein_heavy_dom

DNAH14 DNAH5 DNAH9 DNAH11

1.09e-05151824IPR004273
DomainWD40

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

1.31e-0526818212SM00320
DomainWD40_repeat

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

1.52e-0527218212IPR001680
DomainWD_REPEATS_1

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

1.88e-0527818212PS00678
DomainWD_REPEATS_2

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

1.95e-0527918212PS50082
DomainWD_REPEATS_REGION

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

1.95e-0527918212PS50294
Domain-

FBXW10B FBXW10 AHI1 DCAF4L2 COPA TAF1C EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

2.43e-05333182132.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW10B FBXW10 AHI1 DCAF4L2 COPA TAF1C EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

2.59e-0533518213IPR015943
Domain-

NAA15 TMTC2 ODAD4 TEX11 WDR19 TTC23 SEL1L2 TTC5 CABIN1 NAA16

3.68e-05207182101.25.40.10
DomainTPR

NAA15 TMTC2 ODAD4 TEX11 TTC23 TTC5 CABIN1 NAA16

3.90e-051291828SM00028
DomainTPR_repeat

NAA15 TMTC2 ODAD4 TEX11 TTC23 TTC5 CABIN1 NAA16

4.84e-051331828IPR019734
DomainDHC_N1

DNAH5 DNAH9 DNAH11

4.92e-0581823PF08385
DomainDynein_heavy_dom-1

DNAH5 DNAH9 DNAH11

4.92e-0581823IPR013594
DomainNatA_aux_su

NAA15 NAA16

9.44e-0521822IPR021183
DomainNARP1

NAA15 NAA16

9.44e-0521822PF12569
DomainTPR-like_helical_dom

NAA15 TMTC2 ODAD4 TEX11 WDR19 TTC23 SEL1L2 TTC5 CABIN1 NAA16

9.91e-0523318210IPR011990
DomainTPR_REGION

NAA15 TMTC2 ODAD4 WDR19 TTC23 TTC5 CABIN1 NAA16

2.18e-041651828PS50293
DomainTPR

NAA15 TMTC2 ODAD4 WDR19 TTC23 TTC5 CABIN1 NAA16

2.18e-041651828PS50005
DomainGlyco_transf_25

COLGALT2 COLGALT1

2.82e-0431822PF01755
DomainGlyco_trans_25

COLGALT2 COLGALT1

2.82e-0431822IPR002654
DomainDynein_heavy_dom-2

DNAH5 DNAH9 DNAH11

3.06e-04141823IPR013602
DomainDHC_N2

DNAH5 DNAH9 DNAH11

3.06e-04141823PF08393
DomainATPase_dyneun-rel_AAA

DNAH5 DNAH9 DNAH11

3.06e-04141823IPR011704
DomainAAA_5

DNAH5 DNAH9 DNAH11

3.06e-04141823PF07728
DomainTPR-contain_dom

NAA15 TMTC2 ODAD4 WDR19 TTC5 CABIN1 NAA16

6.79e-041501827IPR013026
DomainYTH

YTHDF1 YTHDF3

9.26e-0451822PF04146
DomainYTH_domain

YTHDF1 YTHDF3

9.26e-0451822IPR007275
DomainYTH

YTHDF1 YTHDF3

9.26e-0451822PS50882
DomainGRAM

OXR1 GRAMD1A NSMAF

1.22e-03221823PF02893
DomainGRAM

OXR1 GRAMD1A NSMAF

1.22e-03221823IPR004182
DomainARM-like

USP9X CKAP5 HUWE1 USP9Y IPO9 RPTOR AP3B2 CFAP69 STAG3

1.36e-032701829IPR011989
DomainHELP

EML2 EML5

1.38e-0361822PF03451
DomainHaem_d1

COPA WDR19

1.38e-0361822IPR011048
DomainHELP

EML2 EML5

1.38e-0361822IPR005108
DomainTPR_2

NAA15 TMTC2 TTC5 NAA16

1.42e-03501824PF07719
DomainTPR_2

NAA15 TMTC2 TTC5 NAA16

1.42e-03501824IPR013105
DomainG-protein_beta_WD-40_rep

FBXW10B FBXW10 COPA DAW1 WDR44

1.45e-03851825IPR020472
DomainARM-type_fold

USP9X CKAP5 HUWE1 USP9Y IPO9 RPTOR AP3B2 TAF2 CFAP69 STAG3

1.85e-0333918210IPR016024
Pubmed

Defining the membrane proteome of NK cells.

KDM3A NAA15 COPA HLA-DQA1 USP9X MARCHF6 HLA-G MYO18A CKAP5 MED14 RNF213 FNDC3A HUWE1 COLGALT1 ALG2 DDX1 ZDHHC20 FASN IPO9 CLCN3 UBR5 OSBPL3 DYNC1LI1 ATIC FERMT3

4.62e-0911681872519946888
Pubmed

CFAP53 regulates mammalian cilia-type motility patterns through differential localization and recruitment of axonemal dynein components.

ODAD4 DNAH5 DNAH9 DNAH11

1.20e-086187433347437
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

KDM3A BRIP1 COPA MYO18A CKAP5 MED14 HUWE1 PHF8 THOC2 SMTN FASN SUGP2 TKT RPTOR EXO1 DYNC1LI1 MICAL3 WDR44

2.32e-077741871815302935
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CFH KDM3A ZSWIM8 USP13 OXR1 COPA USP9X TAF1C ENC1 HECTD4 CKAP5 HUWE1 USP9Y PREPL CNOT8 WDR19 GMCL1 PKD1 ROBO1 MACF1 CHD6 ATIC CABIN1

4.85e-0712851872335914814
Pubmed

Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.

ODAD4 DNAH9 DNAH11

6.09e-074187336140829
Pubmed

DNAH11 Localization in the Proximal Region of Respiratory Cilia Defines Distinct Outer Dynein Arm Complexes.

DNAH5 DNAH9 DNAH11

1.52e-065187326909801
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

NAA15 COPA TAF1C CKAP5 POLRMT HUWE1 COLGALT1 PHF8 DDX1 SMTN FASN IPO9 SUGP2 UBR5 TKT SLC25A1 RPTOR DYNC1LI1 MACF1 ATIC PLCG2 TAF2

4.15e-0613531872229467282
Pubmed

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancer.

NAA15 RNF213 UBR5 ATIC

4.51e-0621187437422473
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH5 DNAH9 DNAH11

5.27e-067187331178125
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

ZNF609 BRIP1 SLF1 ACD FLYWCH1 TOPBP1 MED14 THOC2 SMTN UBR5 SLC25A1 CABIN1

7.05e-064531871229656893
Pubmed

Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2.

USP13 BRIP1 USP9Y IPO9 UBR5 EXO1

7.84e-0687187617148452
Pubmed

CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication.

BRIP1 TOPBP1 PHF8

8.40e-068187333010150
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZSWIM8 NAA15 COPA USP9X CKAP5 POLRMT HUWE1 THOC2 FASN SUGP2 UBR5 MACF1 ATIC HERC5

1.34e-056531871422586326
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

FLYWCH1 RNF213 HUWE1 WDR19 DHTKD1 DNAH5

1.85e-05101187610997877
Pubmed

Phenotypic annotation of the mouse X chromosome.

USP9X MED14 HUWE1 ZDHHC15 WDR44

1.99e-0561187520548051
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ZNF609 HUWE1 SUGP2 ZFYVE26 CABIN1 DNAH9

2.19e-0510418769205841
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

ZNF609 RMND5A USP9X MRPL39 SUGP2 UBR5 MACF1 CHD6 TAF2

2.40e-05282187923667531
Pubmed

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.

USP9X TOPBP1 HUWE1

2.45e-0511187331570706
Pubmed

GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.

COPA CKAP5 POLRMT HUWE1 DDX1 FASN UBR5 SLC25A1

2.82e-05221187829991511
Pubmed

Chronic pancreatitis with polycystic kidney disease: A rare coincidence?

CTRC PKD1

2.88e-052187231862184
Pubmed

Deletion of YTHDF1 (not YTHDF3) reduced brain and gut damage after traumatic brain injury.

YTHDF1 YTHDF3

2.88e-052187239081030
Pubmed

The Deubiquitinase USP13 Maintains Cancer Cell Stemness by Promoting FASN Stability in Small Cell Lung Cancer.

USP13 FASN

2.88e-052187235898882
Pubmed

Mouse germ cell-less as an essential component for nuclear integrity.

GMCL1 GMCL2

2.88e-052187212556490
Pubmed

Molecular basis of BACH1/FANCJ recognition by TopBP1 in DNA replication checkpoint control.

BRIP1 TOPBP1

2.88e-052187221127055
Pubmed

Factor H and CFHR1 polymorphisms associated with atypical Haemolytic Uraemic Syndrome (aHUS) are differently expressed in Tunisian and in Caucasian populations.

CFH CFHR1

2.88e-052187222136554
Pubmed

Deciphering the ligand-binding sites in the Borrelia burgdorferi complement regulator-acquiring surface protein 2 required for interactions with the human immune regulators factor H and factor H-like protein 1.

CFH CFHR1

2.88e-052187218824548
Pubmed

Core glycosylation of collagen is initiated by two beta(1-O)galactosyltransferases.

COLGALT2 COLGALT1

2.88e-052187219075007
Pubmed

Disrupting PHF8-TOPBP1 connection elicits a breast tumor-specific vulnerability to chemotherapeutics.

TOPBP1 PHF8

2.88e-052187235051531
Pubmed

HLA-DQA1 and PLCG2 Are Candidate Risk Loci for Childhood-Onset Steroid-Sensitive Nephrotic Syndrome.

HLA-DQA1 PLCG2

2.88e-052187225349203
Pubmed

Anti-factor H autoantibody-associated hemolytic uremic syndrome: review of literature of the autoimmune form of HUS.

CFH CFHR1

2.88e-052187220865640
Pubmed

A synthetic protein as efficient multitarget regulator against complement over-activation.

CFH CFHR1

2.88e-052187235194132
Pubmed

Complement factor H-related protein 1 deficiency and factor H antibodies in pediatric patients with atypical hemolytic uremic syndrome.

CFH CFHR1

2.88e-052187223243267
Pubmed

Cloning of the 1.4-kb mRNA species of human complement factor H reveals a novel member of the short consensus repeat family related to the carboxy terminal of the classical 150-kDa molecule.

CFH CFHR1

2.88e-05218721826708
Pubmed

Ubiquitin-specific protease activity of USP9Y, a male infertility gene on the Y chromosome.

USP9X USP9Y

2.88e-052187212895410
Pubmed

Human complement factor H and factor H-like protein 1 are expressed in human retinal pigment epithelial cells.

CFH CFHR1

2.88e-052187224280833
Pubmed

A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome.

CFH CFHR1

2.88e-052187223880784
Pubmed

Binding of the human complement regulators CFHR1 and factor H by streptococcal collagen-like protein 1 (Scl1) via their conserved C termini allows control of the complement cascade at multiple levels.

CFH CFHR1

2.88e-052187220855886
Pubmed

Rare variants in dynein heavy chain genes in two individuals with situs inversus and developmental dyslexia: a case report.

DNAH5 DNAH11

2.88e-052187232357925
Pubmed

Complement factor H: a biomarker for progression of cutaneous squamous cell carcinoma.

CFH CFHR1

2.88e-052187223938460
Pubmed

Molecular cloning and genomic organization of mouse homologue of Drosophila germ cell-less and its expression in germ lineage cells.

GMCL1 GMCL2

2.88e-052187210448096
Pubmed

Nxf and Fbxo33: novel seizure-responsive genes in mice.

FBXO33 NPAS4

2.88e-052187215380003
Pubmed

CFH-CFHR1 hybrid genes in two cases of atypical hemolytic uremic syndrome.

CFH CFHR1

2.88e-052187236755127
Pubmed

The Drosophila developmental gene fat facets has a human homologue in Xp11.4 which escapes X-inactivation and has related sequences on Yq11.2.

USP9X USP9Y

2.88e-05218728922996
Pubmed

Deregulation of Factor H by Factor H-Related Protein 1 Depends on Sialylation of Host Surfaces.

CFH CFHR1

2.88e-052187233732239
Pubmed

Cytoplasmic m6A reader YTHDF3 promotes mRNA translation.

YTHDF1 YTHDF3

2.88e-052187228106076
Pubmed

Collagen glycosylation.

COLGALT2 COLGALT1

2.88e-052187230822656
Pubmed

Fatty Acid Synthase Promotes Hepatocellular Carcinoma Growth via S-Phase Kinase-Associated Protein 2/p27KIP1 Regulation.

SKP2 FASN

2.88e-052187239064589
Pubmed

Interaction between complement regulators and Streptococcus pyogenes: binding of C4b-binding protein and factor H/factor H-like protein 1 to M18 strains involves two different cell surface molecules.

CFH CFHR1

2.88e-052187215557185
Pubmed

Factor H-related protein 1 neutralizes anti-factor H autoantibodies in autoimmune hemolytic uremic syndrome.

CFH CFHR1

2.88e-052187221677636
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

2.88e-052187231400758
Pubmed

Usp9y (ubiquitin-specific protease 9 gene on the Y) is associated with a functional promoter and encodes an intact open reading frame homologous to Usp9x that is under selective constraint.

USP9X USP9Y

2.88e-052187212925892
Pubmed

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome.

CFH CFHR1

2.88e-052187222894814
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

2.88e-052187237450367
Pubmed

USP13 regulates the replication stress response by deubiquitinating TopBP1.

USP13 TOPBP1

2.88e-052187233592542
Pubmed

The histone demethylase PHF8 facilitates alternative splicing of the histocompatibility antigen HLA-G.

HLA-G PHF8

2.88e-052187230758047
Pubmed

Ciliary defects and genetics of primary ciliary dyskinesia.

DNAH5 DNAH11

2.88e-052187219410201
Pubmed

Genetic influences on plasma CFH and CFHR1 concentrations and their role in susceptibility to age-related macular degeneration.

CFH CFHR1

2.88e-052187223873044
Pubmed

Stage-specific expression of mouse germ cell-less-1 (mGCL-1), and multiple deformations during mgcl-1 deficient spermatogenesis leading to reduced fertility.

GMCL1 GMCL2

2.88e-052187215700541
Pubmed

The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.

CFH CFHR1

2.88e-052187225659429
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

OXR1 COPA USP9X MYO18A CKAP5 ALG2 DDX1 FASN SARS1 SUGP2 PTPRZ1 TKT NTM AJM1 RPTOR AP3B2 KBTBD11 MACF1 MICAL3 MOB4 DNAH11

3.19e-0514311872137142655
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

LZTR1 TMC6 HECTD4 POLRMT MED14 EML2 HUWE1 IDUA FASN SUGP2 PLEKHM2 RPTOR PKD1 KBTBD11 ZFYVE26 MICAL3 TTC5 CABIN1

3.20e-0511051871835748872
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

NAA15 COPA USP9X CKAP5 HUWE1 THOC2 MEN1 FASN IPO9 UBR5 TKT SLC25A1

3.57e-055341871235032548
Pubmed

A neurogenomics approach to gene expression analysis in the developing brain.

CFH ENC1 THOC2 NTM PKD1 MACF1 ATIC

3.99e-05170187715582152
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

ZNF609 COPA TAF1C MYO18A CKAP5 CNOT8 YTHDF1 SARS1 SUGP2 TKT SECISBP2 MACF1 TAF2 YTHDF3

4.13e-057241871436232890
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

NAA15 COPA USP9X CKAP5 HUWE1 THOC2 DDX1 YTHDF1 FASN IPO9 SARS1 SUGP2 DYNC1LI1

4.61e-056381871333239621
Pubmed

The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking.

AHI1 HUWE1 UBR5 TKT DYNC1LI1 MICAL3 DMBT1

5.15e-05177187726485645
Pubmed

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

USP9X HUWE1 UBR5

5.33e-0514187327626314
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

NAA15 COPA USP9X GRAMD1A FNDC3A HUWE1 DDX1 FASN IPO9 SARS1 UBR5 SLC25A1 RPTOR DYNC1LI1 PLAT ATIC

5.48e-059421871631073040
Pubmed

TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.

COPA USP9X CKAP5 DDX1 FASN IPO9 TKT

5.53e-05179187736261009
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

FBXW10 AHI1 SLF1 FLYWCH1 TMTC2 ODAD4 CNOT8 CLCN3 SIK2 SECISBP2 CCNB1IP1 MOB4 YTHDF3 WDR44

6.02e-057501871411230166
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

CUL2 COPA CKAP5 HUWE1 FASN TKT FBXO33

6.14e-05182187731067453
Pubmed

Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.

COPA USP9X POLRMT HUWE1 UBR5 SLC25A1

6.16e-05125187636030824
Pubmed

Deubiquitinating enzymes: a new class of biological regulators.

USP13 USP9X USP9Y

6.64e-051518739827704
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

CUL2 BRIP1 NAA15 COPA CKAP5 DDX1 AURKA FASN TKT RPTOR YTHDF3

8.21e-054941871126831064
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

LARGE2 AHI1 FLYWCH1 ENC1 HUWE1 COLGALT1 THOC2 CNOT8 MEN1 SMTN AURKA ALKBH8 EML5 OSBPL3 MACF1 CAMTA1 YTHDF3

8.48e-0510841871711544199
Pubmed

Complement factor H: sequence analysis of 221 kb of human genomic DNA containing the entire fH, fHR-1 and fHR-3 genes.

CFH CFHR1

8.60e-053187210781834
Pubmed

YTHDF2 suppresses the plasmablast genetic program and promotes germinal center formation.

YTHDF1 YTHDF3

8.60e-053187235508130
Pubmed

PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting by modulating protein stability of PPARα.

PAQR9 HUWE1

8.60e-053187234474167
Pubmed

ZDHHC20-mediated S-palmitoylation of YTHDF3 stabilizes MYC mRNA to promote pancreatic cancer progression.

ZDHHC20 YTHDF3

8.60e-053187238821916
Pubmed

A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA.

YTHDF1 YTHDF3

8.60e-053187232492408
Pubmed

Variants in Complement Factor H and Complement Factor H-Related Protein Genes, CFHR3 and CFHR1, Affect Complement Activation in IgA Nephropathy.

CFH CFHR1

8.60e-053187225205734
Pubmed

Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency.

CFH CFHR1

8.60e-053187218006700
Pubmed

Deletion of Aurora kinase A prevents the development of polycystic kidney disease in mice.

AURKA PKD1

8.60e-053187238191531
Pubmed

Borrelia recurrentis employs a novel multifunctional surface protein with anti-complement, anti-opsonic and invasive potential to escape innate immunity.

CFH CFHR1

8.60e-053187219308255
Pubmed

Evaluation of CFH Y402H polymorphism and CFHR3/CFHR1 deletion in age-related macular degeneration patients from Brazil.

CFH CFHR1

8.60e-053187226942649
Pubmed

An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD).

CFH CFHR1

8.60e-053187220843825
Pubmed

Menin Upregulates FOXO1 Protein Stability by Repressing Skp2-Mediated Degradation in β Cells.

SKP2 MEN1

8.60e-053187230629029
Pubmed

The corticofugal neuron-associated genes ROBO1, SRGAP1, and CTIP2 exhibit an anterior to posterior gradient of expression in early fetal human neocortex development.

SRGAP1 ROBO1

8.60e-053187221060114
Pubmed

A genome-wide association study identifies key modulators of complement factor H binding to malondialdehyde-epitopes.

CFH CFHR1

8.60e-053187232321835
Pubmed

Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival.

KDM3A HUWE1

8.60e-053187226279298
Pubmed

CtIP- and ATR-dependent FANCJ phosphorylation in response to DNA strand breaks mediated by DNA replication.

BRIP1 TOPBP1

8.60e-053187223157317
Pubmed

Structural characterization of the mouse Hfh4 gene, a developmentally regulated forkhead family member.

FASN KCNJ2

8.60e-05318729367675
Pubmed

Functional ion channels and cell proliferation in 3T3-L1 preadipocytes.

CLCN3 KCNJ2

8.60e-053187221732368
Pubmed

Atypical hemolytic uremic syndrome-associated variants and autoantibodies impair binding of factor h and factor h-related protein 1 to pentraxin 3.

CFH CFHR1

8.60e-053187222786770
Pubmed

m6A-binding YTHDF proteins promote stress granule formation.

YTHDF1 YTHDF3

8.60e-053187232451507
Pubmed

Factor H and factor H-related protein 1 bind to human neutrophils via complement receptor 3, mediate attachment to Candida albicans, and enhance neutrophil antimicrobial activity.

CFH CFHR1

8.60e-053187220008295
Pubmed

TBK1 Knockdown Alleviates Axonal Transport Deficits in Retinal Ganglion Cells Via mTORC1 Activation in a Retinal Damage Mouse Model.

USP9X RPTOR

8.60e-053187237395713
Pubmed

Associations of CFHR1-CFHR3 deletion and a CFH SNP to age-related macular degeneration are not independent.

CFH CFHR1

8.60e-053187220581873
Pubmed

Complement factor H, FHR-3 and FHR-1 variants associate in an extended haplotype conferring increased risk of atypical hemolytic uremic syndrome.

CFH CFHR1

8.60e-053187226163426
Pubmed

Dihydrolipoamide dehydrogenase of Pseudomonas aeruginosa is a surface-exposed immune evasion protein that binds three members of the factor H family and plasminogen.

CFH CFHR1

8.60e-053187223071278
GeneFamilyWD repeat domain containing

FBXW10B FBXW10 AHI1 DCAF4L2 COPA EML2 WDR19 EML5 DAW1 RPTOR NSMAF WDR44

7.45e-0726213712362
GeneFamilyDyneins, axonemal

DNAH14 DNAH5 DNAH9 DNAH11

6.96e-06171374536
GeneFamilyCollagen beta(1-O)galactosyltransferases

COLGALT2 COLGALT1

5.70e-0521372439
GeneFamilyAnkyrin repeat domain containing|BRCA1 B complex

BRIP1 TOPBP1

3.39e-04413721335
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TMTC2 ODAD4 TTC23 TTC5 NAA16

1.83e-031151375769
GeneFamilyZinc fingers SWIM-type|Mitogen-activated protein kinase kinase kinases

ZSWIM8 ZSWIM3

1.98e-039137290
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

3.00e-03111372559
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBXW10 ODAD4 DLEC1 PLCG2 ANKRD45 DNAH5 CFAP69 DNAH9 DNAH11

1.34e-0719418694a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 ATP8A2 GRAMD1A F2RL2 OSBPL3 KBTBD11 CD69 FERMT3

1.10e-0618418688fc047977fad38fcd26eebcc279a688efd342ed8
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ODAD4 WDR19 DAW1 EPHX4 DNAH5 CFAP69 DNAH9 DNAH11

1.24e-06187186804dba2ed09ee4180830bdf0191921696697ea234
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ODAD4 WDR19 DAW1 EPHX4 DNAH5 CFAP69 DNAH9 DNAH11

1.24e-061871868805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCell(04)_Pre-ciliated-(3)_72hpi|(04)_Pre-ciliated / shred by cell type and Timepoint

PI16 CKAP5 EML2 AURKA DLEC1 ANKRD45 DNAH5 CFAP69

1.30e-061881868f911dc61b008b60aaa2a1e9354085f480a669e2c
ToppCell(12)_SLC16A7+|World / shred by cell type by condition

CHDH ZDHHC15 CLMP DLEC1 DNAH5 CFAP69 DNAH9 DNAH11

1.46e-061911868e427eeddd2e87c14376a37db0b43f120c90436bc
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CFH ENC1 TMTC2 DNAH14 PIEZO2 ROBO1 MACF1 CLMP

1.84e-061971868f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma|TCGA-Stomach / Sample_Type by Project: Shred V9

ENC1 TOPBP1 CKAP5 COLGALT1 IPO9 OSBPL3 EXO1 ATIC

1.98e-061991868b10698aee2e6c17bc559eb4f723024141f914b90
ToppCellTCGA-Stomach-Primary_Tumor|TCGA-Stomach / Sample_Type by Project: Shred V9

ENC1 TOPBP1 CKAP5 COLGALT1 IPO9 OSBPL3 EXO1 ATIC

1.98e-06199186838f1f612b29feb868322999ceeda78e52447ec4f
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

GABRG3 AHI1 SLF1 OXR1 ATP8A2 PREPL PKD1 ANKRD30BL

2.06e-06200186848d801219bc771d6c7e151dc88ca4c179988de85
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 GCNT4 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

3.01e-061481867d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 GCNT4 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

3.01e-061481867c8e93b87212f55774223caa385859c566fa1981f
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 DAW1 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

3.92e-0615418674e3bc24043144143842627cacf6f90dda2228910
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 DAW1 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

3.92e-0615418677556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 PTPRZ1 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

4.09e-0615518675f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 PTPRZ1 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

4.09e-0615518670944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL12RB2 BRIP1 ACD HLA-DQA1 LALBA ATP10A DAW1

4.45e-0615718676730b775308f45a2f3946016bdbb7f8e5b5efe49
ToppCellfacs-Heart-LV-24m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC C10orf90 H1-9P CRYGC CRYGS AKAP4 PLAAT5

5.70e-061631867648d5439811b64412bc4678646f216105b90b9a1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LARGE2 TMTC2 ADARB2 KCNJ2 SRGAP1 CLMP DNAH11

7.22e-061691867eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-mature_NK_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 ATP8A2 F2RL2 OSBPL3 KBTBD11 CD69 FERMT3

7.80e-061711867d322cc042a6f4b4aa8ef80ae977edbce9e266d48
ToppCellE18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HECTD4 F2RL2 SMTN SUGP2 CD69 NPAS4 FERMT3

1.09e-0518018674e9e8cde2919610c4ac0025b1c9819808048bc1d
ToppCellE18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HECTD4 F2RL2 SMTN SUGP2 CD69 NPAS4 FERMT3

1.09e-051801867ca2a35bfb67347e47f511589a3d0f763e6664634
ToppCellE18.5-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HECTD4 F2RL2 SMTN SUGP2 CD69 NPAS4 FERMT3

1.09e-051801867466381bf93c3da6a2a241daadb68e9aad2964eae
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

ODAD4 DAW1 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

1.21e-051831867cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

ODAD4 DAW1 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

1.21e-051831867b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH ATP8A2 F2RL2 ROBO1 PLAT CLMP DNAH5

1.44e-051881867997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 ATP8A2 GRAMD1A F2RL2 KBTBD11 CD69 FERMT3

1.49e-051891867039b1922c85aa749d6578583d9d41a4eef8a6ac4
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GABRG3 PIEZO2 NTM SRGAP1 ROBO1 CLMP CFAP69

1.55e-05190186745df8fee00f8949937863159d7aa042e72748d9b
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_activate-7|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LARGE2 FCRL2 HLA-DQA1 CD69 MICAL3 STAG3 HERC5

1.60e-0519118672feab42ac6d29fa4eac78f3f78a5f8aa0a559523
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OXR1 USP9X MYO18A PIEZO2 MACF1 PLCG2 FERMT3

1.65e-0519218671ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPRZ1 DLEC1 ANKRD45 DNAH5 CFAP69 DNAH9 DNAH11

1.71e-051931867ea345d34440b25f65358a53dc72831998d1c3620
ToppCellControl-CD8+_T_naive|Control / Disease condition and Cell class

ZNF609 CD248 ATP8A2 GRAMD1A CD101 ROBO1 NAA16

1.71e-051931867627d345baf1940218c61907305705298e473dbab
ToppCellhuman_hepatoblastoma-Tumor_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

HGD CHDH DNAH14 SCMH1 RPTOR ROBO1 CHD6

1.71e-051931867503a979328c68b096680b71359a26f02fafdff35
ToppCellnormal_Lymph_Node-T/NK_cells-CD8_low_T|T/NK_cells / Location, Cell class and cell subclass

SLF1 HLA-DQA1 ENC1 COLGALT2 GZMK PLCG2 CLEC2B

1.71e-05193186748809047d3194aff225fc43c3d5152c20434fe62
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CFHR1 FCRL2 AHI1 SAMD8 HLA-DQA1 MICAL3 PLCG2

1.77e-051941867d852aebf7a763b9a776c4570711f0c759f591910
ToppCellnormal_Lymph_Node-T/NK_cells-Naive_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

SLF1 HLA-DQA1 ENC1 COLGALT2 GZMK PLCG2 CLEC2B

1.77e-05194186772749ab1dd36a0d58624328961e1db08ccba2686
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

GABRG3 PIEZO2 CLCN3 NTM ROBO1 MACF1 PLAT

1.77e-051941867b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell(1)_T_cells-(1)_T_CD8_activated|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

SLF1 HLA-DQA1 ENC1 RNF213 GZMK CD69 CLEC2B

1.77e-051941867e3f288b58525c1f34db4459d3e83e0df695adfc7
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

SLF1 HLA-DQA1 CD101 GZMK CD69 CLEC2B CPNE7

1.77e-0519418677b8fe5b702b99aac5bff7de8ac0b5cabb3235b56
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ODAD4 OSBPL3 DLEC1 DNAH5 CFAP69 DNAH9 DNAH11

1.95e-05197186774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellnormal_Pleural_Fluid-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

SLF1 HLA-DQA1 RNF213 GZMK CD69 CLEC2B CPNE7

1.95e-0519718672bf540fa228687a71f595a807e4a2af20588a82c
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GABRG3 AHI1 SLF1 OXR1 ATP8A2 PREPL ANKRD30BL

2.02e-0519818670ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCelldistal-Epithelial-Ciliated-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ODAD4 DAW1 DLEC1 DNAH5 CFAP69 DNAH9 DNAH11

2.08e-0519918672de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

LARGE2 ACD ENC1 YTHDF1 AURKA ATIC CPNE7

2.08e-051991867cdcdef1d95a8e476de016b1e11ee010438834be0
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

LARGE2 GRAMD1A ENC1 AURKA OSBPL3 EPHX4 VWA2

2.08e-05199186785b3b1ad01368dae4adbc9da7efc148e49992f69
ToppCellTCGA-Colorectal-Primary_Tumor|TCGA-Colorectal / Sample_Type by Project: Shred V9

LARGE2 GRAMD1A ENC1 AURKA OSBPL3 EPHX4 VWA2

2.08e-051991867c7d6a8398f2419b726a0461585d1ee0561654e3b
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CFH CD248 ATP10A SMTN CRYGS SLCO2A1 PLCG2

2.08e-0519918671295f34a350bf48987e2fad411aaac3630efd3f1
ToppCelldistal-2-Epithelial-Ciliated|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ODAD4 DAW1 DLEC1 DNAH5 CFAP69 DNAH9 DNAH11

2.08e-05199186797b66b82c76c7bc1fcd7da7b94dd2aa2d4d70a60
ToppCellSepsis-Int-URO-Lymphocyte-T/NK-dn_T|Int-URO / Disease, condition lineage and cell class

RMND5A MEN1 UBR5 RPTOR GZMK MTBP ZFYVE26

2.15e-052001867020439d9e70fff7246650ab0e9105236688c3ec3
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFH CD248 PIEZO2 NTM SRGAP1 ROBO1 CLMP

2.15e-05200186754806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ODAD4 PTPRZ1 DAW1 DLEC1 ANKRD45 DNAH5 DNAH9

2.15e-05200186796701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC46A2 PIEZO2 SLCO2A1 EXO1 PLAT DMBT1

3.46e-051461866281144e293e8c93a425c2606d2188cb2838e667f
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

3.59e-0514718669bc4185920b2b0f1fd5c6e2ec5583b9cd49c2efd
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

3.59e-0514718669b0f87a6dd5224c2b06deafeae04a1b04e53eb75
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

4.66e-0515418663c64111e2ca1bb04ddd1ecb19938a307778ff7eb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

4.66e-051541866c6f1a0806d492b1f01cded2daffaf3f13422deb6
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

4.66e-0515418669ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

4.66e-051541866665885d8aca168513ab7a65f70d52181c821eb78
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ODAD4 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

4.66e-05154186658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellCOVID-CD4-antiviral_CD4|COVID / Condition, Cell_class and T cell subcluster

CFH BRIP1 FLYWCH1 COLGALT2 GMCL1 CD69

4.83e-0515518667e5ae034036fe85915d38a24195501e6d3bcbfb0
ToppCell5'-Adult-Appendix-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CADM4 ATP8A2 NTM SRGAP1 PLCG2 EPHX4

5.00e-05156186658b9520fce6e259b36c3d59e82b712f5e7729e3e
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRZ1 OSBPL3 DLEC1 ANKRD45 DNAH5 DNAH11

5.96e-051611866472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCellfacs-SCAT-Fat-24m|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

6.17e-051621866b824f30c723c9c7d8e8c8a8dc3f88d4eed29dd67
ToppCellfacs-SCAT-Fat-24m-Epithelial|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

6.39e-051631866ade2f59bca0ab0c4856202f980464f3287bddd24
ToppCellfacs-SCAT-Fat-24m-Epithelial-nan|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

6.39e-0516318669fd2e495efb6c447cdc52efdb3b695cb2fa8b914
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ZNF609 BRIP1 POLRMT CTRC ASMT DNAH5

6.39e-051631866e4077e587895c85bc806be05ff5d451088e39468
ToppCellfacs-SCAT-Fat-24m-Epithelial-epithelial_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

6.39e-051631866aaf5d96bab1957c7bde84c741c7f2fb86ef41e8b
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-MAIT_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC6 CILP2 GZMK CD69 FERMT3 CPNE7

6.61e-051641866aff5138b35a06b0819e52855744797bfa343633a
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8A2 VASH1 F2RL2 ZDHHC15 SUGP2 CD101

6.83e-0516518668c7a6f9e2ca0ce077426d3d0726e3f5a4c03b296
ToppCellfacs-BAT-Fat-24m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

7.06e-051661866001a31aaa4ab4d5606b894faf6fcaad524405064
ToppCellfacs-BAT-Fat-24m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

7.06e-051661866c71ad3fc6a14507609d17756431d3deff9fda418
ToppCellfacs-Heart-LV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI16 CTRC CRYGC CRYGS AKAP4 STAG3

7.06e-051661866c02c2a68d61dbd7ed086d9b02cfcb1778b8a8656
ToppCellfacs-Heart-LV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PI16 CTRC CRYGC CRYGS AKAP4 STAG3

7.06e-05166186620c24a9d2eb67a20e5154d25656da14186034f02
ToppCellfacs-BAT-Fat-24m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC H1-9P CRYGC CRYGS AKAP4 PLAAT5

7.06e-05166186631ed1290b4a977eabfc29674a5c593985bff6a74
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DQA1 CTRC IFNB1 CD163L1 CD69 GPR132

7.06e-05166186600c53ee34ff4b988a9accd296bc0a2e14d9e7c49
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

BCORL1 MAMDC4 ATP10A POLR3F DYNC1LI1 CPNE7

7.55e-0516818663fb79aaa858057c82645a90bd139fc4f096323c7
ToppCellfacs-Trachea-nan-24m-Mesenchymal-smooth_muscle_cell_of_trachea|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZSWIM3 HHATL EML5 AP3B2 NPAS4 PLAAT5

7.55e-0516818666c7b490b6c844d0ea4c07edfc24c02284f9533c4
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC46A2 AKAP4 AJM1 AP3B2 ANKRD45 NPAS4

8.06e-051701866941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CKAP5 CTRC MUC19 POLR3F AURKA EXO1

8.06e-05170186612aa9bdb18f3bf6da2a25984d08fe9497e5570ed
ToppCellwk_20-22-Mesenchymal-Chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFH SHC4 F2RL2 DNAH14 CILP2 PTPRZ1

8.32e-051711866d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCellfacs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTRC CRYGC GZMK KBTBD11 CD69 GPR132

8.59e-051721866a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFH HLA-DQA1 F2RL2 EML5 EXO1 ATIC

9.16e-05174186609b091e24317c3f7bac043f04762a533e30793de
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Dedifferentiated_Liposarcoma|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

CFH IL12RB2 CD248 COLGALT2 CD163L1 KBTBD11

9.45e-0517518662eca4c168dea2017ea0e383006e28abed22f32ec
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 ATP8A2 GZMK KBTBD11 CD69 GPR132

9.45e-051751866a72c6ceca5ddbd34f652e7302defefa2d105e17e
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB2 ATP8A2 GZMK KBTBD11 CD69 GPR132

9.45e-0517518669a462e9e6f7bbb64abb09ad6c080df3576073540
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHDH ODAD4 HHATL CFAP69 DNAH9 PLAAT5

9.75e-05176186687de432c680b80555342afac864599bbc002c040
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Drd1_(Deep_layer_pyramidal_cells)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

IL12RB2 SAMD8 PHF8 KCNH4 MINDY3 NSMAF

9.75e-0517618663c76a5c4ca2b378667cb155fbb9675519572b35d
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHDH OSBPL3 CD163L1 PRSS50 CD69 GPR132

1.01e-041771866be35bb178fbc149f8a12984c012d98b486325ba9
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL2 CD163L1 GZMK KBTBD11 CD69 GPR132

1.01e-04177186631201a72b7c1bdb0eff892b7072a35c80fd34727
ToppCellfacs-Heart-RA-18m-Lymphocytic-T_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL2 CD163L1 GZMK KBTBD11 CD69 GPR132

1.01e-04177186689d0131320cd96af8b0ee54f0f4d4771d17ef44e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADARB2 PTPRZ1 KCNJ2 CD163L1 EXO1 ROBO1

1.04e-0417818662a36475c260088f69f3b8c282d910e5eaa5c5c2d
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LARGE2 FCRL2 HLA-DQA1 CD69 MICAL3 STAG3

1.04e-0417818665d41fede13c8e64b6fdaf2155f1eb72bcfc32fdb
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DLEC1 ANKRD45 DNAH5 CFAP69 DNAH9 DNAH11

1.07e-0417918668a66d197a2f55d763ff7ef0bec89ee96f59c3937
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

USP13 SLCO2A1 PLAT PLCG2 NPAS4 CLEC2B

1.07e-041791866754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellfacs-Trachea-18m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DLEC1 ANKRD45 DNAH5 CFAP69 DNAH9 DNAH11

1.07e-041791866d4efbc34f52136039b96451fd0b0a0ad164197c6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HHATL DLEC1 DNAH5 CFAP69 DNAH9 DNAH11

1.07e-0417918665e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DQA1 TOPBP1 SECISBP2 CD69 DMBT1 GPR132

1.14e-04181186657f82f54e20e19aa17a2ea22af22e3bc8965d622
ToppCellfacs-Heart-LV-18m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HLA-DQA1 TOPBP1 SECISBP2 CD69 DMBT1 GPR132

1.14e-0418118668855812c85ef45c1be6bd511619b2dfe5e441264
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ODAD4 DLEC1 ANKRD45 DNAH5 DNAH9 DNAH11

1.14e-041811866dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADARB2 PTPRZ1 KCNJ2 CD163L1 EXO1 ROBO1

1.17e-041821866d3a037268f026eb2f84428b1821022503cef7756
Diseaseroundabout homolog 1 measurement

CFH ROBO1

3.78e-0521822EFO_0803039
DiseaseKartagener syndrome (implicated_via_orthology)

DAW1 DNAH5 DNAH11

7.99e-05141823DOID:0050144 (implicated_via_orthology)
Diseaseanaphase-promoting complex subunit 7 measurement

CFH CFHR1

1.13e-0431822EFO_0801381
DiseaseHEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1

CFH CFHR1

1.13e-0431822C2749604
DiseaseHEMOLYTIC UREMIC SYNDROME, ATYPICAL, SUSCEPTIBILITY TO, 1

CFH CFHR1

1.13e-0431822235400
Diseasecalnexin measurement

CFH CFHR1

1.13e-0431822EFO_0801444
DiseaseHemolytic uremic syndrome, atypical, susceptibility to, 1

CFH CFHR1

1.13e-0431822cv:C2749604
Diseasecomplement factor H-related protein 4A measurement

CFH CFHR1

1.13e-0431822EFO_0600057
Diseasehistone-lysine N-methyltransferase 2D measurement

CFH CFHR1

1.13e-0431822EFO_0801683
Diseaseglucose-6-phosphate isomerase measurement

CFH CD163L1

1.13e-0431822EFO_0020407
DiseasePrimary Ciliary Dyskinesia

ODAD4 DNAH5 DNAH9 DNAH11

2.03e-04471824C4551720
DiseaseCongenital Myasthenic Syndromes, Presynaptic

PREPL ALG2 SLC25A1

2.08e-04191823C0751884
Diseaseresponse to radiation

C10orf90 ADARB2 ATP10A CLMP DNAH5

2.19e-04881825GO_0009314
Diseasegestational age

OXR1 HLA-DQA1 C10orf90 UBR5 DLEC1 CAMTA1

2.22e-041381826EFO_0005112
DiseaseNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement

CFH CFHR1

2.25e-0441822EFO_0803292
Diseaseleucine-rich repeat transmembrane protein FLRT3 measurement

CFH SEL1L2

2.25e-0441822EFO_0021861
Diseasekallikrein-5 measurement

CFH CFHR1

2.25e-0441822EFO_0020515
DiseaseKartagener syndrome (is_implicated_in)

DNAH5 DNAH11

2.25e-0441822DOID:0050144 (is_implicated_in)
DiseaseAneuploidy

CKAP5 AURKA

3.74e-0451822C0002938
DiseasePolyarthritis

COPA CD69

3.74e-0451822C0162323
Diseasebrain infarction (is_implicated_in)

CFH HLA-DQA1

3.74e-0451822DOID:3454 (is_implicated_in)
Diseaseprobable ATP-dependent RNA helicase DHX58 measurement

CFH KCNH4

3.74e-0451822EFO_0802901
DiseaseMalignant neoplasm of breast

KDM3A BRIP1 BCORL1 MED14 COLGALT2 MAMDC4 IFNB1 AURKA FASN ALKBH8 DAW1 EXO1 ROBO1 MACF1 ZFYVE26 DLEC1 DNAH9

3.75e-04107418217C0006142
Diseasenon-Hodgkins lymphoma

HLA-DQA1 NTM CD69

4.80e-04251823EFO_0005952
DiseaseIntellectual Disability

AHI1 NAA15 OXR1 ATP8A2 PREPL FASN ALKBH8 MACF1 ATIC TAF2

4.87e-0444718210C3714756
DiseaseL lactate dehydrogenase measurement

CFH HLA-DQA1 CD163L1

5.41e-04261823EFO_0004808
DiseaseMembranoproliferative Glomerulonephritis, Type II

CFH CFHR1

5.58e-0461822C0268743
Diseasecomplement C1s subcomponent measurement

CFH CFHR1

5.58e-0461822EFO_0008091
DiseaseArthritis

COPA CD69

5.58e-0461822C0003864
Diseasenon-alcoholic fatty liver disease, type 2 diabetes mellitus

GPR26 ATP8A2 SHC4 ROBO1 PLCG2

6.13e-041101825EFO_0003095, MONDO_0005148
Diseasepleckstrin homology domain-containing family A member 1 measurement

CFH DMBT1

7.79e-0471822EFO_0802873
Diseasetumor necrosis factor receptor superfamily member 6 measurement

HLA-DQA1 FASN

7.79e-0471822EFO_0010610
Diseaseosteocalcin measurement

CFH HLA-DQA1

7.79e-0471822EFO_0010232
Diseasereticulocyte count

RMND5A OXR1 HLA-DQA1 USP9X GRAMD1A TMC6 ENC1 HECTD4 HLA-G ODAD4 CNOT8 STK16 PKD1 PLCG2 TAF2 FERMT3

7.94e-04104518216EFO_0007986
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

HUWE1 PHF8

1.03e-0381822DOID:0060309 (implicated_via_orthology)
DiseaseChromosomal Instability

CKAP5 AURKA

1.03e-0381822C1257806
Diseasemotor function measurement, response to zonisamide, response to levodopa

CD69 CAMTA1

1.03e-0381822EFO_0010747, EFO_0010748, EFO_0010749
Diseaseopioid-binding protein/cell adhesion molecule measurement

CFH NTM

1.03e-0381822EFO_0020618
DiseasePAX-interacting protein 1 measurement

CFH HLA-DQA1

1.03e-0381822EFO_0801868
Diseaseantiphospholipid syndrome (is_implicated_in)

HLA-DQA1 PLAT

1.03e-0381822DOID:2988 (is_implicated_in)
Diseasegdnf family receptor alpha-1 measurement

CFH HLA-DQA1

1.03e-0381822EFO_0020400
Diseaseatypical hemolytic-uremic syndrome (is_implicated_in)

CFH CFHR1

1.03e-0381822DOID:0080301 (is_implicated_in)
DiseaseInflammatory Bowel Diseases

CUL2 MUC19 PLCG2

1.31e-03351823C0021390
Diseasezinc fingers and homeoboxes protein 3 measurement

CFH HLA-DQA1

1.32e-0391822EFO_0803299
DiseaseAtypical hemolytic-uremic syndrome

CFH CFHR1

1.32e-0391822cv:C2931788
DiseaseC3 glomerulopathy

CFH CFHR1

1.32e-0391822C4087273
Diseaseendothelin-converting enzyme 1 measurement

PAQR9 CFH

1.32e-0391822EFO_0008121
DiseaseHemolytic-uremic syndrome

CFH CFHR1

1.32e-0391822cv:C0019061
Diseaseleukocyte immunoglobulin-like receptor subfamily A member 5 measurement

CFH CFHR1

1.32e-0391822EFO_0801766
DiseaseHLA class II histocompatibility antigen, DQ alpha 2 chain measurement

CFH HLA-DQA1

1.32e-0391822EFO_0801686
DiseasePrimary ciliary dyskinesia

ODAD4 DNAH5 DNAH11

1.42e-03361823cv:C0008780
Diseasevisceral heterotaxy (implicated_via_orthology)

DAW1 DNAH5 DNAH11

1.54e-03371823DOID:0050545 (implicated_via_orthology)
Diseaseubiquitin-conjugating enzyme E2 G2 measurement

CFH HLA-DQA1

1.65e-03101822EFO_0022035
DiseaseAtypical Hemolytic Uremic Syndrome

CFH CFHR1

1.65e-03101822C2931788
Diseasegastric adenocarcinoma (is_implicated_in)

HLA-DQA1 UBR5

2.01e-03111822DOID:3717 (is_implicated_in)
Diseasehemopexin measurement

CFH CFHR1

2.01e-03111822EFO_0008149
Diseasefactor VIII deficiency (is_implicated_in)

HLA-DQA1 PLAT

2.01e-03111822DOID:12134 (is_implicated_in)
Diseaseforced expiratory volume, body mass index

HLA-DQA1 HECTD4

2.01e-03111822EFO_0004314, EFO_0004340
DiseaseConnective Tissue Diseases

PIEZO2 PKD1

2.82e-03131822C0009782
Diseaseselective IgA deficiency disease

AHI1 HLA-DQA1 FASN

2.88e-03461823EFO_1001929
DiseaseNeuroblastoma

IFNB1 AURKA CHD6

3.07e-03471823C0027819
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD1 KIF28P

3.28e-03141822DOID:898 (implicated_via_orthology)
Diseasenodular sclerosis Hodgkin lymphoma

AHI1 HLA-DQA1

3.28e-03141822EFO_0004708
DiseaseC-C motif chemokine 19 measurement

CFH HLA-DQA1

3.28e-03141822EFO_0008047
DiseaseSitus ambiguus

DNAH5 DNAH9

3.77e-03151822C0266642
Diseaselifestyle measurement, depressive symptom measurement

ADARB2 MINDY3 KBTBD11 NSMAF

4.12e-031051824EFO_0007006, EFO_0010724
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

PREPL ALG2

4.29e-03161822C0751885
DiseaseColorectal Carcinoma

CD248 EML2 ADARB2 KCNH4 SMTN AURKA GMCL2 SLCO2A1 EXO1 ZNF480 VWA2

4.38e-0370218211C0009402
DiseaseLiver carcinoma

DCAF4L2 SKP2 AURKA FASN KBTBD11 EXO1 ROBO1 MTBP HERC5

4.40e-035071829C2239176
Diseasehair morphology measurement

SLF1 ADARB2 RPTOR

4.54e-03541823EFO_0007821
Diseaseresponse to phenylephrine

F2RL2 ATP10A

4.84e-03171822EFO_0010152
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

PREPL ALG2

4.84e-03171822C0751883
DiseaseCiliopathies

AHI1 WDR19 DNAH5 DNAH11

4.86e-031101824C4277690
Diseasesyndrome (implicated_via_orthology)

ZDHHC20 ZDHHC15

5.42e-03181822DOID:225 (implicated_via_orthology)
DiseaseAge-related macular degeneration

CFH CFHR1

5.42e-03181822cv:C0242383
Diseaselupus nephritis (is_implicated_in)

CFH HLA-DQA1

5.42e-03181822DOID:0080162 (is_implicated_in)
DiseaseC-C motif chemokine 3 measurement

CFH PLCG2

5.42e-03181822EFO_0008051
DiseaseAutistic Disorder

AHI1 LZTR1 TAF1C ATP10A ASMT ROBO1

5.77e-032611826C0004352
Diseaseprimary ciliary dyskinesia (implicated_via_orthology)

DAW1 DNAH5

6.04e-03191822DOID:9562 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
CGHYTQVVWAKTERI

PI16

126

Q6UXB8
KLRLWYHAASGDVAE

MAMDC4

141

Q6UXC1
WACALGHLEAAVVLY

CAMTA1

1116

Q9Y6Y1
HDEKVDLWSLGVLCY

AURKA

306

O14965
WLRSHRGVCKVDLYN

AKAP4

16

Q5JQC9
CGHLNIIYDLSWSKD

AHI1

651

Q8N157
SRYLWTHGITCRKFD

ALKBH8

286

Q96BT7
RITDCYRWVIHAGSK

CD248

721

Q9HCU0
WVLTAAHCQYRFTKG

GZMK

61

P49863
YIVSSCERGLVKVWH

FBXW10

546

Q5XX13
YTALHEACSRGWTDI

BCORL1

1531

Q5H9F3
EDWDAHKARCVYGRV

AJM1

701

C9J069
KTTRGYTLLHCAAAW

ANKRD45

106

Q5TZF3
YTLLHCAAAWGRLET

ANKRD45

111

Q5TZF3
DHYDWGLRAIKSVLV

DNAH11

2061

Q96DT5
GHITDDWDRKLCRVY

DNAH11

4146

Q96DT5
DWADGKCSHLLERIY

ASMT

256

P46597
SHTLRTTCWDGKLEY

CFH

1211

P08603
RHGKIWLDDVSCYGN

CD163L1

106

Q9NR16
KDVIIDLLCYRQWGH

DHTKD1

421

Q96HY7
LRFVLSKHWGDDCYL

C5orf38

66

Q86SI9
SAEESYDCKVEHWGL

HLA-DQA1

181

P01909
WSGDSKCHQRRVLTY

GRAMD1A

411

Q96CP6
VHGAWSYNRVTKCIL

ATP8A2

866

Q9NTI2
RVLSKEEYACWLQSH

ATP10A

816

O60312
TIHEGKRWSAACAYL

CHDH

231

Q8NE62
RASILWLIGEYCEHV

AP3B2

501

Q13367
KICALGEEWSLHKIY

GMCL1

111

Q96IK5
GEEWSLHKIYLCQSG

GMCL1

116

Q96IK5
LCKHVLSARWARLYG

ADARB2

666

Q9NS39
ERCYSEASDLKVIHW

LARGE2

326

Q8N3Y3
CRSSYLANEILWGHR

KCNJ2

311

P63252
AHLLRFYDGICKWEE

MEN1

416

O00255
YIVSSCERGLVKVWH

FBXW10B

546

O95170
HVSSCSEDWVGYQRK

CD69

81

Q07108
GTCVEWLHRYLENGK

HLA-G

186

P17693
HSGSYCLVSWLRGKT

MINDY3

101

Q9H8M7
SWKSGLALCAIIHRY

MICAL3

546

Q7RTP6
HKYWLDTSEACARVI

NRBP2

106

Q9NSY0
ETHFDRGINDWLCKY

HHATL

336

Q9HCP6
KCTLHEDYGRLWESR

LZTR1

426

Q8N653
RSTILYAGNDKWCLD

NTM

71

Q9P121
DSLGYSKCVLIGHDW

EPHX4

156

Q8IUS5
VGDKVYWTCRDHALH

FLYWCH1

296

Q4VC44
CLTSGEWARHYFLNK

KMT5B

156

Q4FZB7
ETCYRLHGVDHWISK

KIAA2026

166

Q5HYC2
KASVSRCTLYWRDEG

IL12RB2

236

Q99665
GCLLHYRIYWKERDS

IL12RB2

551

Q99665
RCNVWILDGDLYHKG

DYNC1LI1

116

Q9Y6G9
AVGQDCYTRIWSLRH

DCAF4L2

331

Q8NA75
CTKLSLLAIHGYTVW

FBXO33

456

Q7Z6M2
TEKEKVWYHVCSSRG

DDX1

621

Q92499
IGSHWGVLSKCLAYS

GPR26

271

Q8NDV2
KETYIVGWRTGLCEH

MUC19

1061

Q7Z5P9
RHEWAQKAAYLLGCS

MYO18A

691

Q92614
VCWHVYGLLQRSDKK

NAA16

81

Q6N069
GVWLKRKHAYICLAA

OPN5

141

Q6U736
LWSVETGKCYHTFRG

DAW1

161

Q8N136
VLWDYTADLDVHGKV

HEXD

221

Q8WVB3
KWRDGLCSKTVEYHR

KCT2

231

Q8NC54
RCLLLHYSVSKAIWD

KCNH4

216

Q9UQ05
DIKGIDYWLAHKALC

LALBA

116

P00709
WTGTAKIHELYTAAC

MARCHF6

666

O60337
SIDQKWTRHYCAIAD

PLCG2

486

P16885
VGILIYWRKCFQTAH

PTPRZ1

1656

P23471
RSVWRAILSCGYDLH

HECTD4

3426

Q9Y4D8
IGKCELYHWVDLLDR

HUWE1

46

Q7Z6Z7
VCWHVYGLLQRSDKK

NAA15

81

Q9BXJ9
VLGDYRACHGTLIKW

MACF1

1276

Q9UPN3
LGWHVDCTRLIAAYR

PAQR9

196

Q6ZVX9
VERYHAGKCLSLSVW

MED14

326

O60244
KHTYALVTCGLVWAT

F2RL2

206

O00254
LVERDYESACKIWSG

BRIP1

456

Q9BX63
ACGRWHTLAYVSDLG

HERC5

301

Q9UII4
LKEWTGLHDAYLETR

SMPD2

191

O60906
WLDGDLYHGRSHSCK

OXR1

836

Q8N573
ERSELLCKSWYGLLH

NPAS4

241

Q8IUM7
WHLDRKYGSCSTILL

CCNYL3

11

P0C7X3
CEHKLWKARLSGYEE

CKAP5

16

Q14008
SDRGKYHCAVEEWLL

CD101

771

Q93033
LYDVGDIVHSVRAKW

KDM3A

731

Q9Y4C1
SLQYLKNDTWRHTCG

CTRC

46

Q99895
LLNTAHEYLGRRSWC

CABIN1

891

Q9Y6J0
HLRSVCIYGAAELRW

GCNT4

386

Q9P109
YEECKSGSWRKGRIH

GABRG3

421

Q99928
TGEEVTHYLVKWCSL

CHD6

391

Q8TD26
EIHSCKVLEGVWIFY

CRYGS

126

P22914
ESKAWEVDTCRGHYN

COPA

236

P53621
KWEMIYSGATREHLC

FNDC3A

611

Q9Y2H6
LKCLVWDYDSRGKHD

CPNE7

301

Q9UBL6
AKEYSHCAWTIVRVE

IFNB1

156

P01574
RKLTWLHYLCTGEVK

CUL2

551

Q13617
WCSVRQKGSYLTHEA

CADM4

346

Q8NFZ8
HAYRSCKPLSSWIDD

DNAH14

3251

Q0VDD8
EHVGSKCLWTYEIQF

IDUA

571

P35475
IWGYCDQLKVSESTH

IPO9

541

Q96P70
AVSKICWHDNRLYSA

NSMAF

716

Q92636
VLCDNVKWLSFHSGY

CNOT8

146

Q9UFF9
IRSLHVLEGCWVLYE

CRYGC

121

P07315
SDAHQCTKLYELSWR

ENC1

156

O14682
LITCGKSHIYFWTLE

EML2

221

O95834
YKGLSVRSVCWRGDH

EML5

281

Q05BV3
CKGATSYITHIDWDI

EML5

1121

Q05BV3
CVKSTWDLIRLYLHE

DNAH9

2696

Q9NYC9
DTGSYWCKAETVTHR

FCRL2

171

Q96LA5
TVSISAVELKYCHGW

H1-9P

76

P60008
HTLRTTCWDGKLEYP

CFHR1

311

Q03591
GCFLSHYNIWKEVVD

COLGALT1

411

Q8NBJ5
IGCFLSHYSVWKEVI

COLGALT2

411

Q8IYK4
LAAYWRGQCIKEAHL

FASN

601

P49327
CIIHRYLDFKIGEIW

CFAP69

746

A5D8W1
YLWGKISDCHIIEVE

DLEC1

791

Q9Y238
LDDVRCSGHESYLWS

DMBT1

166

Q9UGM3
LDDVRCSGHESYLWS

DMBT1

666

Q9UGM3
VLDDVRCSGHESYLW

DMBT1

796

Q9UGM3
VLDDVRCSGHESYLW

DMBT1

1056

Q9UGM3
LDDVRCSGHESYLWS

DMBT1

1186

Q9UGM3
RKGLTFVSVHDCYWT

POLRMT

1141

O00411
RLGSAHIWLQSLAYC

KIF28P

636

B7ZC32
TLHYAWEKLLARAGE

DNAH5

1301

Q8TE73
WYSAKITIAGNHCEI

MTBP

196

Q96DY7
AVHRLFGKWHESIYC

OSBPL3

746

Q9H4L5
NGHCYRLVVEKAAWL

PKD1

416

P98161
WGLKASRCLDENYHK

HGD

411

Q93099
YLGKEHWKTCFVVLS

PLEKHM2

786

Q8IWE5
HWKTCFVVLSNGILY

PLEKHM2

791

Q8IWE5
HRWTLGLLACKVTAY

GPR132

106

Q9UNW8
ERIWGDCTVRKKYSH

SARS1

156

P49591
KVVRGSASDWYDALC

USP9X

2061

Q93008
SEWYCRKSILALVDG

MRPL39

96

Q9NYK5
EVDLGKKCWYHSIFA

RMND5A

321

Q9H871
KGASLLLYHRASEDW

SRGAP1

766

Q7Z6B7
VAYCLRERGAKHEAW

STK16

81

O75716
EGVWKYEHLRQFCLE

MOB4

66

Q9Y3A3
CTGKIYGSVWEKLHR

SAMD8

261

Q96LT4
AVELYKGVCELGHWA

SEL1L2

466

Q5TEA6
ALLAVRSDYHCAVWK

TAF1C

306

Q15572
TSHDWRLRCGAVDLY

TAF2

961

Q6P1X5
KTWLFHEIGRCYLEL

ODAD4

396

Q96NG3
GEEWRLHKIYLCQSG

GMCL2

116

Q8NEA9
RKFWQILSAVDYCHG

SIK2

121

Q9H0K1
IEIWKKHLEAYSGCT

SECISBP2

821

Q96T21
ASSHEVWKYICELGI

POLR3F

211

Q9H1D9
YCIATGRHMLKDDWT

WDR19

1276

Q8NEZ3
VVAVDTYCWLHKGAI

EXO1

26

Q9UQ84
GVSVSRYHCLAKQWS

KBTBD11

521

O94819
ARWCGVRDSAHEKLY

RPTOR

591

Q8N122
GHFTWDKYLKETCSV

SCMH1

26

Q96GD3
KKRTALYWACANGHA

ANKRD30BL

71

A7E2S9
HWAASRCKATGEAVY

ACD

206

Q96AP0
QARGCSVKIWTAHYD

ALG2

41

Q9H553
CKVKNSGRYVWSHVI

CLMP

111

Q9H6B4
RIKLSGYAWVTACSH

CCNB1IP1

16

Q9NPC3
IYHCKAWNEAGAVRS

CILP2

356

Q8IUL8
FLRRYKCSSDHWIGL

CLEC2B

81

Q92478
LKEGICLSALWYNHE

CLCN3

156

P51790
EAHTGLCERRKYWVT

C10orf90

211

Q96M02
LWSEECYHGKLSRKA

SHC4

521

Q6S5L8
LYGLTIDHSCIRWNS

SLCO2A1

571

Q92959
SGVCKRWYRLASDES

SKP2

121

Q13309
SKWDSNICELHYTRD

RNF213

411

Q63HN8
EDDIHRSIKYSIWCS

YTHDF3

426

Q7Z739
RSIKYSIWCSTEHGN

YTHDF3

431

Q7Z739
SLFSYHCWLVGKNRT

ZDHHC20

226

Q5W0Z9
WTECELSGYGKHEAL

PLAT

441

P00750
TRWHSDRATYEKECG

THOC2

1051

Q8NI27
IYQKRCEAFGWHAII

TKT

201

P29401
YLVDSLWDCAGARLK

STAG3

496

Q9UJ98
IKHCSTRGYSARTWG

TMTC2

156

Q8N394
EYIDHLKAWLVSSGC

SUGP2

526

Q8IX01
IYAHIFILKCWRESE

PIEZO2

2371

Q9H5I5
KTYVGTLLDCTRHDW

ZNF609

336

O15014
EVYWKKGDVAAAHTC

TTC5

111

Q8N0Z6
YHQDVLIEWLCGEAK

VWA2

696

Q5GFL6
CKYKGHTADLLDLSW

WDR44

601

Q5JSH3
LEAHKYRNTWDCGLQ

SLC25A1

251

P53007
ILLEWCRSKTLGYQH

SMTNL2

356

Q2TAL5
SKYASAEKWCGLALR

TEX11

881

Q8IYF3
VLVDDGWILAYCHVR

PREPL

496

Q4J6C6
THWTLDKYGILADAR

FERMT3

76

Q86UX7
WCLGNETRYHINKTV

ROBO1

816

Q9Y6N7
WYDALCVLLRHSKNV

USP9Y

2071

O00507
RIHCTRLAGDKANYW

ATIC

451

P31939
DYIIHSAKSGRWLDE

SLF1

71

Q9BQI6
CGKAFSRISYLAQHW

ZNF480

516

Q8WV37
TYSGTDRKLALCWAR

ZSWIM8

496

A7E2V4
SGSELAYKLCHNEWE

ZSWIM3

501

Q96MP5
LGWLSDRYHRKISIC

SLC46A2

96

Q9BY10
ETICWYVGKHILDIF

PHF8

401

Q9UPP1
CVALTRICYGDSHWK

TTC23

71

Q5W5X9
RICYGDSHWKLAEAH

TTC23

76

Q5W5X9
SGIHAITVFCSWDYK

TMC6

376

Q7Z403
KYSRLEDVLHGCSWK

PLAAT5

181

Q96KN8
DYVLKDHSRCTVTGW

PRSS50

231

Q9UI38
LDFEAAYGRCWHVLK

VASH1

241

Q7L8A9
KWVLHRSYLEACRTA

TOPBP1

1326

Q92547
LESWGKYLIAACQHL

ZFYVE26

2231

Q68DK2
LDWCRAKTRGYEHVD

SMTN

806

P53814
EGRWVIYNDHKVCAS

USP13

831

Q92995
VHAVLKTGNWVRYCI

UBR5

756

O95071
IKYSIWCSTEHGNKR

YTHDF1

406

Q9BYJ9
FGYHCWLVSRNKTTL

ZDHHC15

231

Q96MV8