Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.56e-12	26	117	8	GO:0005248
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B	1.77e-11	52	117	9	GO:0005272
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B	3.71e-10	171	117	12	GO:0015081
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN3A SCN8A SCN9A	1.22e-08	14	117	5	GO:0031402
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	TMEM87A SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ATP2B1 KCNH5	9.22e-08	465	117	15	GO:0046873
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN3A SCN8A SCN9A	3.78e-07	26	117	5	GO:0031420
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRG1 ABCA4 SLC44A4 TMEM87A SVOPL SLC5A4 SLC6A8 SLC9A4 SIDT2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ABCG2 ABCC2 ATP2B1 KCNH5	1.20e-06	1180	117	22	GO:0022857
GeneOntologyMolecularFunction	transporter activity	GABRG1 ABCA4 SLC44A4 TMEM87A SVOPL SLC5A4 SLC6A8 SLC9A4 SIDT2 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO SCNN1B ABCG2 ABCC2 ATP2B1 KCNH5	1.40e-06	1289	117	23	GO:0005215
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRG1 TMEM87A SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ABCC2 ATP2B1 KCNH5	2.02e-06	758	117	17	GO:0015318
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH3 DNAH7 DNAH1 DNAH6	3.22e-06	18	117	4	GO:0008569
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	TMEM87A SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ATP2B1 KCNH5	3.94e-06	627	117	15	GO:0022890
GeneOntologyMolecularFunction	monoatomic cation channel activity	TMEM87A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	5.61e-06	343	117	11	GO:0005261
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	TMEM87A SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ATP2B1 KCNH5	7.85e-06	664	117	15	GO:0008324
GeneOntologyMolecularFunction	G protein-coupled receptor activity	VN1R2 OR11G2 SIGMAR1 MCHR2 ADGRB2 ADGRB3 OR6C65 ADGRV1 ADGRL4 ADORA2A GPR161 HCAR3 CELSR1 TAS2R5 GPR158 MRGPRX1 TAS2R20	1.54e-05	884	117	17	GO:0004930
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRG1 TMEM87A SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ATP2B1 KCNH5	1.56e-05	793	117	16	GO:0015075
GeneOntologyMolecularFunction	monoatomic ion channel activity	GABRG1 TMEM87A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	1.63e-05	459	117	12	GO:0005216
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH3 DNAH7 DNAH1 DNAH6	2.06e-05	28	117	4	GO:0051959
GeneOntologyMolecularFunction	channel activity	GABRG1 TMEM87A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	6.03e-05	525	117	12	GO:0015267
GeneOntologyMolecularFunction	passive transmembrane transporter activity	GABRG1 TMEM87A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	6.14e-05	526	117	12	GO:0022803
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH3 DNAH7 DNAH1 DNAH6	6.37e-05	37	117	4	GO:0045505
GeneOntologyMolecularFunction	glucose-6-phosphatase activity	G6PC2 G6PC1	1.02e-04	3	117	2	GO:0004346
GeneOntologyMolecularFunction	sugar-terminal-phosphatase activity	G6PC2 G6PC1	1.02e-04	3	117	2	GO:0050309
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	VN1R2 GABRG1 LILRB3 OR11G2 SIGMAR1 MCHR2 ADGRB2 ADGRB3 OR6C65 ADGRV1 ADGRL4 ADORA2A GPR161 HCAR3 CELSR1 IGF2R TAS2R5 GPR158 MRGPRX1 TAS2R20	1.10e-04	1353	117	20	GO:0004888
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	SCN1A SCN2A SCN10A	1.26e-04	17	117	3	GO:0099508
GeneOntologyMolecularFunction	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	SCN5A SCN10A	5.03e-04	6	117	2	GO:0086006
GeneOntologyMolecularFunction	microtubule motor activity	DNAH3 DNAH7 DNAH1 DNAH6	7.62e-04	70	117	4	GO:0003777
GeneOntologyMolecularFunction	choline transmembrane transporter activity	SLC44A4 SLC6A8	9.31e-04	8	117	2	GO:0015220
GeneOntologyMolecularFunction	vitamin transmembrane transporter activity	ABCA4 SLC44A4 ABCG2	1.22e-03	36	117	3	GO:0090482
GeneOntologyMolecularFunction	sugar-phosphatase activity	G6PC2 G6PC1	1.49e-03	10	117	2	GO:0050308
GeneOntologyMolecularFunction	benzodiazepine receptor activity	GABRG1 TSPO	1.81e-03	11	117	2	GO:0008503
GeneOntologyMolecularFunction	carbohydrate phosphatase activity	G6PC2 G6PC1	1.81e-03	11	117	2	GO:0019203
GeneOntologyMolecularFunction	calmodulin binding	ADORA2A SCN2A SCN3A SCN5A ATP2B1 KCNH5	2.37e-03	230	117	6	GO:0005516
GeneOntologyMolecularFunction	retinoid binding	ABCA4 CYP26B1 IGF2R	2.80e-03	48	117	3	GO:0005501
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCA4 ABCG2 ABCC2	2.97e-03	49	117	3	GO:0140359
GeneOntologyMolecularFunction	isoprenoid binding	ABCA4 CYP26B1 IGF2R	2.97e-03	49	117	3	GO:0019840
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCG2 ABCC2	3.40e-03	15	117	2	GO:0008559
GeneOntologyMolecularFunction	transmembrane transporter binding	TCAF2 SCN5A SCN10A TSPO KCNH5	3.45e-03	172	117	5	GO:0044325
GeneOntologyMolecularFunction	gated channel activity	GABRG1 TMEM87A SCN1A SCN2A SCN10A SCNN1B KCNH5	3.55e-03	334	117	7	GO:0022836
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCA4 ABCG2 ABCC2 ATP2B1	3.88e-03	109	117	4	GO:0042626
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	2.39e-11	36	118	8	GO:0086010
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD	2.10e-10	208	118	13	GO:0035725
GeneOntologyBiologicalProcess	cardiac muscle cell action potential	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD	1.70e-09	87	118	9	GO:0086001
GeneOntologyBiologicalProcess	membrane depolarization	ADORA2A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO	1.89e-09	121	118	10	GO:0051899
GeneOntologyBiologicalProcess	cardiac muscle cell action potential involved in contraction	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	2.36e-09	62	118	8	GO:0086002
GeneOntologyBiologicalProcess	neuronal action potential	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	2.69e-09	63	118	8	GO:0019228
GeneOntologyBiologicalProcess	sodium ion transport	SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD	6.34e-09	275	118	13	GO:0006814
GeneOntologyBiologicalProcess	actin-mediated cell contraction	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A EMP2	4.86e-08	127	118	9	GO:0070252
GeneOntologyBiologicalProcess	cardiac muscle cell contraction	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	6.13e-08	93	118	8	GO:0086003
GeneOntologyBiologicalProcess	actin filament-based movement	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A EMP2	2.41e-07	153	118	9	GO:0030048
GeneOntologyBiologicalProcess	transmission of nerve impulse	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	2.62e-07	112	118	8	GO:0019226
GeneOntologyBiologicalProcess	cardiac muscle contraction	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD	5.06e-07	167	118	9	GO:0060048
GeneOntologyBiologicalProcess	detection of mechanical stimulus involved in sensory perception	ADGRV1 TMEM87A SCN1A PTPRQ SCN9A SCN10A	8.82e-07	57	118	6	GO:0050974
GeneOntologyBiologicalProcess	action potential	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD	2.37e-06	201	118	9	GO:0001508
GeneOntologyBiologicalProcess	muscle contraction	SLC6A8 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD ATP2B1	3.22e-06	400	118	12	GO:0006936
GeneOntologyBiologicalProcess	metal ion transport	SPG11 SLC5A4 ADORA2A SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO SCNN1B DMD ABCC2 ATP2B1 KCNH5	3.89e-06	1000	118	19	GO:0030001
GeneOntologyBiologicalProcess	circulatory system process	ADORA2A NAMPT SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B ABCG2 DMD ABCC2 EMP2 ATP2B1	4.38e-06	733	118	16	GO:0003013
GeneOntologyBiologicalProcess	striated muscle contraction	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD	4.44e-06	217	118	9	GO:0006941
GeneOntologyBiologicalProcess	detection of mechanical stimulus	ADGRV1 TMEM87A SCN1A PTPRQ SCN9A SCN10A	4.50e-06	75	118	6	GO:0050982
GeneOntologyBiologicalProcess	heart contraction	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD ATP2B1	8.40e-06	298	118	10	GO:0060047
GeneOntologyBiologicalProcess	heart process	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD ATP2B1	1.15e-05	309	118	10	GO:0003015
GeneOntologyBiologicalProcess	muscle system process	SLC6A8 FDPS SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD ATP2B1	1.53e-05	547	118	13	GO:0003012
GeneOntologyBiologicalProcess	regulation of membrane potential	GABRG1 ADORA2A SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO DMD KCNH5	1.92e-05	559	118	13	GO:0042391
GeneOntologyBiologicalProcess	blood circulation	ADORA2A NAMPT SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD EMP2 ATP2B1	2.04e-05	648	118	14	GO:0008015
GeneOntologyBiologicalProcess	monoatomic cation transport	SPG11 SLC5A4 ADORA2A SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO SCNN1B DMD ABCC2 ATP2B1 KCNH5	3.03e-05	1157	118	19	GO:0006812
GeneOntologyBiologicalProcess	monoatomic ion transport	GABRG1 TCAF2 SPG11 SLC5A4 ADORA2A SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO SCNN1B DMD ABCC2 ATP2B1 KCNH5	3.17e-05	1374	118	21	GO:0006811
GeneOntologyBiologicalProcess	behavioral response to pain	SCN3A SCN9A SCN10A TSPO	3.23e-05	32	118	4	GO:0048266
GeneOntologyBiologicalProcess	behavior	DPP4 ADGRB3 SPG11 ADORA2A CELSR1 TAS2R5 RPTOR MRGPRX1 SCN1A SCN2A SCN3A SCN8A SCN9A SCN10A TSPO DMD	4.82e-05	891	118	16	GO:0007610
GeneOntologyBiologicalProcess	detection of external stimulus	ABCA4 ADGRV1 TMEM87A SCN1A PTPRQ SCN9A SCN10A	6.24e-05	173	118	7	GO:0009581
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	GABRG1 TCAF2 SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD ABCC2 ATP2B1 KCNH5	6.26e-05	1115	118	18	GO:0034220
GeneOntologyBiologicalProcess	transepithelial transport	SLC9A4 SCNN1B ABCG2 ABCC2	6.46e-05	38	118	4	GO:0070633
GeneOntologyBiologicalProcess	inorganic ion transmembrane transport	GABRG1 SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD ABCC2 ATP2B1 KCNH5	6.69e-05	1017	118	17	GO:0098660
GeneOntologyBiologicalProcess	detection of abiotic stimulus	ABCA4 ADGRV1 TMEM87A SCN1A PTPRQ SCN9A SCN10A	6.71e-05	175	118	7	GO:0009582
GeneOntologyBiologicalProcess	inorganic cation transmembrane transport	SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD ABCC2 ATP2B1 KCNH5	7.22e-05	922	118	16	GO:0098662
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC5A4 SLC6A8 SLC9A4 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD ABCC2 ATP2B1 KCNH5	9.28e-05	942	118	16	GO:0098655
GeneOntologyBiologicalProcess	response to pain	SCN3A SCN9A SCN10A TSPO	2.07e-04	51	118	4	GO:0048265
GeneOntologyBiologicalProcess	determination of adult lifespan	SCN1A SCN2A ATM DMD	2.58e-04	54	118	4	GO:0008340
GeneOntologyBiologicalProcess	walking behavior	SPG11 SCN1A SCN8A DMD	3.88e-04	60	118	4	GO:0090659
GeneOntologyBiologicalProcess	sensory perception of mechanical stimulus	ADGRV1 TMEM87A SCN1A PTPRQ SCN8A SCN9A SCN10A	4.44e-04	238	118	7	GO:0050954
GeneOntologyBiologicalProcess	xenobiotic transport across blood-brain barrier	ABCG2 ABCC2	4.80e-04	6	118	2	GO:1990962
GeneOntologyBiologicalProcess	sodium ion import across plasma membrane	SLC9A4 SCN5A SCNN1B	4.83e-04	27	118	3	GO:0098719
GeneOntologyBiologicalProcess	response to mechanical stimulus	ADGRV1 TMEM87A SCN1A PTPRQ SCN9A SCN10A DMD	5.54e-04	247	118	7	GO:0009612
GeneOntologyBiologicalProcess	regulation of hormone levels	DPP4 CYP26B1 SRD5A3 HCAR3 SIDT2 RPTOR DHCR7 TSPO SCNN1B G6PC2 ABCC2 NR0B2	5.55e-04	684	118	12	GO:0010817
GeneOntologyBiologicalProcess	bundle of His cell action potential	SCN5A SCN10A	6.69e-04	7	118	2	GO:0086043
GeneOntologyBiologicalProcess	bundle of His cell to Purkinje myocyte signaling	SCN5A SCN10A	6.69e-04	7	118	2	GO:0086028
GeneOntologyBiologicalProcess	chemosensory behavior	TAS2R5 MRGPRX1 SCN9A	7.30e-04	31	118	3	GO:0007635
GeneOntologyBiologicalProcess	multicellular organismal response to stress	DPP4 SCN3A SCN9A SCN10A TSPO	7.92e-04	126	118	5	GO:0033555
GeneOntologyBiologicalProcess	glucose 6-phosphate metabolic process	RPTOR G6PC2 G6PC1	8.02e-04	32	118	3	GO:0051156
GeneOntologyBiologicalProcess	acetylcholine secretion	SLC44A4 ADORA2A	8.88e-04	8	118	2	GO:0061526
GeneOntologyBiologicalProcess	detection of stimulus	ABCA4 OR11G2 OR6C65 ADGRV1 TMEM87A TAS2R5 SCN1A PTPRQ SCN9A SCN10A TSPO TAS2R20	8.90e-04	722	118	12	GO:0051606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	VN1R2 OR11G2 SIGMAR1 MCHR2 ADGRB2 ADGRB3 OR6C65 ADGRV1 ADGRL4 ADORA2A GPR161 HCAR3 CELSR1 IGF2R TAS2R5 GPR158 MRGPRX1 TAS2R20	9.55e-04	1395	118	18	GO:0007186
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	2.02e-14	17	119	8	GO:0001518
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B	4.20e-14	29	119	9	GO:0034706
GeneOntologyCellularComponent	inner dynein arm	DNAH3 DNAH7 DNAH1 DNAH6	2.04e-07	10	119	4	GO:0036156
GeneOntologyCellularComponent	axonemal dynein complex	DNAH3 DNAH7 DNAH1 DNAI4 DNAH6	2.66e-07	25	119	5	GO:0005858
GeneOntologyCellularComponent	cation channel complex	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	9.71e-07	235	119	10	GO:0034703
GeneOntologyCellularComponent	monoatomic ion channel complex	GABRG1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	1.08e-05	378	119	11	GO:0034702
GeneOntologyCellularComponent	dynein complex	DNAH3 DNAH7 DNAH1 DNAI4 DNAH6	1.39e-05	54	119	5	GO:0030286
GeneOntologyCellularComponent	synaptic membrane	GABRG1 SIGMAR1 ADGRB3 ADORA2A SLC6A8 GPR158 SCN1A SCN2A SCN8A SCN10A DMD ATP2B1	1.25e-04	583	119	12	GO:0097060
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A SCN8A	1.91e-04	20	119	3	GO:0033268
GeneOntologyCellularComponent	transmembrane transporter complex	GABRG1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	2.00e-04	523	119	11	GO:1902495
GeneOntologyCellularComponent	transporter complex	GABRG1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B KCNH5	3.08e-04	550	119	11	GO:1990351
GeneOntologyCellularComponent	apical plasma membrane	DPP4 SLC44A4 SLC6A8 SLC9A4 PTPRQ SCNN1B ABCG2 ABCC2 EMP2 ATP2B1	4.74e-04	487	119	10	GO:0016324
GeneOntologyCellularComponent	plasma membrane protein complex	LILRB3 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD TRAV23DV6 TRAV20 KCNH5	5.35e-04	785	119	13	GO:0098797
GeneOntologyCellularComponent	axon initial segment	SCN1A SCN2A SCN8A	5.90e-04	29	119	3	GO:0043194
GeneOntologyCellularComponent	cell projection membrane	GABRG1 DPP4 ADGRV1 ADORA2A GPR161 ABCG2 DMD ABCC2 ATP2B1	8.12e-04	431	119	9	GO:0031253
GeneOntologyCellularComponent	presynaptic membrane	ADORA2A GPR158 SCN1A SCN2A SCN8A SCN10A ATP2B1	1.05e-03	277	119	7	GO:0042734
GeneOntologyCellularComponent	intercellular canaliculus	DPP4 ABCC2	1.13e-03	9	119	2	GO:0046581
GeneOntologyCellularComponent	neuron projection membrane	GABRG1 ADGRV1 ADORA2A ATP2B1	1.24e-03	82	119	4	GO:0032589
GeneOntologyCellularComponent	lysosomal membrane	GPR155 DPP4 VPS39 SPG11 PLA2G4E TMEM179B SIDT2 SPPL2A RPTOR	1.32e-03	462	119	9	GO:0005765
GeneOntologyCellularComponent	lytic vacuole membrane	GPR155 DPP4 VPS39 SPG11 PLA2G4E TMEM179B SIDT2 SPPL2A RPTOR	1.32e-03	462	119	9	GO:0098852
GeneOntologyCellularComponent	main axon	ADORA2A SCN1A SCN2A SCN8A	1.68e-03	89	119	4	GO:0044304
GeneOntologyCellularComponent	axon	SIGMAR1 SPG11 ADORA2A MRGPRX1 SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD	1.69e-03	891	119	13	GO:0030424
GeneOntologyCellularComponent	apical part of cell	DPP4 SLC44A4 SLC6A8 SLC9A4 PTPRQ SCNN1B ABCG2 ABCC2 EMP2 ATP2B1	2.07e-03	592	119	10	GO:0045177
GeneOntologyCellularComponent	postsynaptic membrane	GABRG1 SIGMAR1 ADGRB3 ADORA2A SLC6A8 GPR158 SCN8A DMD	2.24e-03	405	119	8	GO:0045211
GeneOntologyCellularComponent	microtubule associated complex	DNAH3 DNAH7 DNAH1 DNAI4 DNAH6	2.30e-03	161	119	5	GO:0005875
GeneOntologyCellularComponent	vacuolar membrane	GPR155 DPP4 VPS39 SPG11 PLA2G4E TMEM179B SIDT2 SPPL2A RPTOR	2.48e-03	507	119	9	GO:0005774
GeneOntologyCellularComponent	cell surface	DPP4 SLAMF9 ADGRV1 IGF2R MRC2 MRGPRX1 SCN5A SCNN1B ABCG2 TMEM102 DMD ABCC2 EMP2 KCNH5	4.29e-03	1111	119	14	GO:0009986
HumanPheno	Complex febrile seizure	ADORA2A SCN1A SCN2A SCN8A SCN9A	1.55e-07	16	44	5	HP:0011172
HumanPheno	Focal hemiclonic seizure	SCN1A SCN2A SCN8A SCN9A KCNH5	1.78e-06	25	44	5	HP:0006813
HumanPheno	Status epilepticus without prominent motor symptoms	ADGRV1 ADORA2A SCN1A SCN2A SCN9A	2.67e-06	27	44	5	HP:0031475
HumanPheno	Generalized cerebral atrophy/hypoplasia	ADGRV1 SCN1A SCN2A SCN9A	3.27e-06	13	44	4	HP:0007058
HumanPheno	Childhood onset	TPP2 CCDC134 ABCA4 NUP85 SIGMAR1 SPG11 ADGRV1 STAT2 DNAH1 SCN1A SCN2A SCN3A PTPRQ SCN5A SCN8A SCNN1B ATM DMD ATP2B1 G6PC1 KCNH5	8.07e-06	938	44	21	HP:0011463
HumanPheno	Calcaneovalgus deformity	ADAMTSL1 ADGRV1 SCN1A SCN2A SCN9A	8.80e-06	34	44	5	HP:0001848
HumanPheno	Deformed tarsal bones	ADAMTSL1 ADGRV1 SCN1A SCN2A SCN9A	1.02e-05	35	44	5	HP:0008119
HumanPheno	Atypical absence status epilepticus	ADGRV1 SCN1A SCN2A SCN9A	1.06e-05	17	44	4	HP:0011151
HumanPheno	Generalized non-convulsive status epilepticus without coma	ADGRV1 SCN1A SCN2A SCN9A	1.36e-05	18	44	4	HP:0032860
HumanPheno	Non-convulsive status epilepticus without coma	ADGRV1 SCN1A SCN2A SCN9A	2.12e-05	20	44	4	HP:0032671
HumanPheno	Focal clonic seizure	SCN1A SCN2A SCN8A SCN9A KCNH5	2.56e-05	42	44	5	HP:0002266
HumanPheno	Talipes valgus	ADGRV1 SCN1A SCN2A SCN9A	2.60e-05	21	44	4	HP:0004684
HumanPheno	Photosensitive myoclonic seizure	SCN1A SCN2A SCN9A	3.27e-05	8	44	3	HP:0001327
HumanPheno	Cyanotic episode	SCN1A SCN2A SCN9A	3.27e-05	8	44	3	HP:0200048
HumanPheno	Tibial torsion	ADGRV1 SCN1A SCN2A SCN9A	3.81e-05	23	44	4	HP:0100694
HumanPheno	Clonic seizure	SCN1A SCN2A SCN3A SCN8A SCN9A KCNH5	5.85e-05	81	44	6	HP:0020221
HumanPheno	Limited knee extension	ADGRV1 SCN1A SCN2A SCN9A	7.36e-05	27	44	4	HP:0003066
HumanPheno	Simple febrile seizure	SCN1A SCN2A SCN3A SCN8A	7.36e-05	27	44	4	HP:0011171
HumanPheno	Focal aware seizure	SCN1A SCN2A SCN9A KCNH5	8.53e-05	28	44	4	HP:0002349
HumanPheno	Focal impaired awareness seizure	ADGRV1 SCN1A SCN2A SCN3A SCN8A SCN9A KCNH5	8.58e-05	126	44	7	HP:0002384
HumanPheno	Limited neck range of motion	SCN1A SCN2A SCN9A	9.46e-05	11	44	3	HP:0000466
HumanPheno	Abnormality of the calcaneus	ADAMTSL1 ADGRV1 SCN1A SCN2A SCN9A	1.14e-04	57	44	5	HP:0008364
HumanPheno	Epilepsia partialis continua	SCN1A SCN2A SCN9A	1.25e-04	12	44	3	HP:0012847
HumanPheno	Focal automatism seizure	SCN1A SCN2A SCN8A	1.25e-04	12	44	3	HP:0032898
HumanPheno	Obsessive-compulsive trait	ADGRV1 SCN1A SCN2A SCN9A	1.65e-04	33	44	4	HP:0008770
HumanPheno	Generalized clonic seizure	SCN1A SCN2A SCN8A SCN9A	1.86e-04	34	44	4	HP:0011169
HumanPheno	Generalized tonic seizure	ADGRV1 SCN1A SCN2A SCN8A SCN9A	1.99e-04	64	44	5	HP:0010818
HumanPheno	Infection-related seizure	ADGRV1 ADORA2A SCN1A SCN2A SCN3A SCN8A SCN9A	2.08e-04	145	44	7	HP:0032892
HumanPheno	Seizure precipitated by febrile infection	ADGRV1 ADORA2A SCN1A SCN2A SCN3A SCN8A SCN9A	2.08e-04	145	44	7	HP:0032894
HumanPheno	Febrile seizure (within the age range of 3 months to 6 years)	ADGRV1 ADORA2A SCN1A SCN2A SCN3A SCN8A SCN9A	2.08e-04	145	44	7	HP:0002373
HumanPheno	Limitation of knee mobility	ADGRV1 SCN1A SCN2A SCN9A	2.09e-04	35	44	4	HP:0010501
HumanPheno	Facial tics	SCN1A SCN2A SCN9A	2.55e-04	15	44	3	HP:0011468
HumanPheno	Photosensitive tonic-clonic seizure	SCN1A SCN2A SCN9A	2.55e-04	15	44	3	HP:0007207
HumanPheno	Dysgenesis of the hippocampus	SCN1A SCN2A SCN9A	3.11e-04	16	44	3	HP:0025101
HumanPheno	Status epilepticus	ADGRV1 ADORA2A SCN1A SCN2A SCN3A SCN8A SCN9A KCNH5	3.25e-04	207	44	8	HP:0002133
HumanPheno	Focal motor status epilepticus	SCN1A SCN2A SCN9A	3.76e-04	17	44	3	HP:0032663
HumanPheno	Visually-induced seizure	SCN1A SCN2A SCN9A	4.48e-04	18	44	3	HP:0020216
HumanPheno	Atypical absence seizure	ADGRV1 SCN1A SCN2A SCN9A	6.07e-04	46	44	4	HP:0007270
HumanPheno	Neonatal electro-clinical non-motor seizure	SCN2A SCN8A	7.17e-04	5	44	2	HP:0032812
HumanPheno	Neonatal seizure with electrographic correlate	SCN2A SCN8A	7.17e-04	5	44	2	HP:0032808
HumanPheno	Neonatal electro-clinical seizure	SCN2A SCN8A	7.17e-04	5	44	2	HP:0032809
HumanPheno	Neonatal electro-clinical seizure with behavior arrest	SCN2A SCN8A	7.17e-04	5	44	2	HP:0032823
HumanPheno	Focal head nodding automatism seizure	SCN2A SCN8A	7.17e-04	5	44	2	HP:0032906
HumanPheno	Esophoria	KIDINS220 SCN8A	7.17e-04	5	44	2	HP:0025312
HumanPheno	Allodynia	SCN9A SCN10A	7.17e-04	5	44	2	HP:0012533
HumanPheno	Reflex seizure	SCN1A SCN2A SCN9A	8.26e-04	22	44	3	HP:0020207
HumanPheno	EEG with spike-wave complexes	ADGRV1 SCN1A SCN2A SCN8A SCN9A	8.77e-04	88	44	5	HP:0010850
HumanPheno	Focal tonic seizure	SCN2A SCN8A KCNH5	9.44e-04	23	44	3	HP:0011167
HumanPheno	Bilateral tonic-clonic seizure with focal onset	SCN1A SCN2A SCN8A KCNH5	9.70e-04	52	44	4	HP:0007334
Domain	Na_channel_asu	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	6.22e-17	10	113	8	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	6.22e-17	10	113	8	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	6.22e-17	10	113	8	PF06512
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A	4.29e-14	6	113	6	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A	4.29e-14	6	113	6	IPR024583
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.80e-09	57	113	8	IPR027359
Domain	-	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.80e-09	57	113	8	1.20.120.350
Domain	Ion_trans_dom	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A KCNH5	3.00e-08	114	113	9	IPR005821
Domain	Ion_trans	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A KCNH5	3.00e-08	114	113	9	PF00520
Domain	IQ_motif_EF-hand-BS	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	7.17e-08	90	113	8	IPR000048
Domain	IQ	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	9.29e-08	93	113	8	PS50096
Domain	GAIN_dom_N	ADGRB2 ADGRB3 ADGRL4 CELSR1	4.06e-07	11	113	4	IPR032471
Domain	GAIN	ADGRB2 ADGRB3 ADGRL4 CELSR1	4.06e-07	11	113	4	PF16489
Domain	IQ	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A	5.92e-07	81	113	7	SM00015
Domain	Dynein_heavy_chain_D4_dom	DNAH3 DNAH7 DNAH1 DNAH6	1.21e-06	14	113	4	IPR024317
Domain	Dynein_HC_stalk	DNAH3 DNAH7 DNAH1 DNAH6	1.21e-06	14	113	4	IPR024743
Domain	Dynein_heavy_dom-2	DNAH3 DNAH7 DNAH1 DNAH6	1.21e-06	14	113	4	IPR013602
Domain	DHC_N2	DNAH3 DNAH7 DNAH1 DNAH6	1.21e-06	14	113	4	PF08393
Domain	MT	DNAH3 DNAH7 DNAH1 DNAH6	1.21e-06	14	113	4	PF12777
Domain	AAA_8	DNAH3 DNAH7 DNAH1 DNAH6	1.21e-06	14	113	4	PF12780
Domain	DHC_fam	DNAH3 DNAH7 DNAH1 DNAH6	1.65e-06	15	113	4	IPR026983
Domain	Dynein_heavy_dom	DNAH3 DNAH7 DNAH1 DNAH6	1.65e-06	15	113	4	IPR004273
Domain	Dynein_heavy	DNAH3 DNAH7 DNAH1 DNAH6	1.65e-06	15	113	4	PF03028
Domain	GPS	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	1.79e-06	34	113	5	SM00303
Domain	GPS	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	2.08e-06	35	113	5	PF01825
Domain	GPS	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	2.41e-06	36	113	5	PS50221
Domain	GPS	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	2.77e-06	37	113	5	IPR000203
Domain	IQ	SCN1A SCN3A SCN4A SCN8A SCN9A SCN10A	4.46e-06	71	113	6	PF00612
Domain	G_PROTEIN_RECEP_F2_2	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	1.26e-05	50	113	5	PS00650
Domain	7tm_2	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	1.26e-05	50	113	5	PF00002
Domain	GPCR_2_secretin-like	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	3.11e-05	60	113	5	IPR000832
Domain	GPCR_2-like	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	3.11e-05	60	113	5	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	3.37e-05	61	113	5	PS50261
Domain	ATPase_dyneun-rel_AAA	DNAH3 DNAH1 DNAH6	7.48e-05	14	113	3	IPR011704
Domain	AAA_5	DNAH3 DNAH1 DNAH6	7.48e-05	14	113	3	PF07728
Domain	G_PROTEIN_RECEP_F2_1	ADGRB2 ADGRB3 ADGRV1 CELSR1	9.81e-05	40	113	4	PS00649
Domain	GPCR_2_extracellular_dom	ADGRB2 ADGRB3 ADGRV1 CELSR1	9.81e-05	40	113	4	IPR001879
Domain	G_PROTEIN_RECEP_F2_3	ADGRB2 ADGRB3 ADGRV1 CELSR1	9.81e-05	40	113	4	PS50227
Domain	GPCR_2_brain_angio_inhib	ADGRB2 ADGRB3	1.08e-04	3	113	2	IPR008077
Domain	Glucose-6-phosphatase	G6PC2 G6PC1	1.08e-04	3	113	2	IPR016275
Domain	AAA+_ATPase	DNAH3 ABCA4 DNAH7 ABCG2 ABCC2 DNAH6	2.43e-04	144	113	6	IPR003593
Domain	AAA	DNAH3 ABCA4 DNAH7 ABCG2 ABCC2 DNAH6	2.43e-04	144	113	6	SM00382
Domain	HormR	ADGRB2 ADGRB3 CELSR1	4.50e-04	25	113	3	SM00008
Domain	HRM	ADGRB2 ADGRB3 CELSR1	6.33e-04	28	113	3	PF02793
Domain	-	IGF2R MRC2	2.71e-03	13	113	2	2.10.10.10
Domain	ABC_tran	ABCA4 ABCG2 ABCC2	3.06e-03	48	113	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA4 ABCG2 ABCC2	3.06e-03	48	113	3	PS50893
Domain	FN_type2_col-bd	IGF2R MRC2	3.15e-03	14	113	2	IPR000562
Domain	FN2_2	IGF2R MRC2	3.15e-03	14	113	2	PS51092
Domain	fn2	IGF2R MRC2	3.15e-03	14	113	2	PF00040
Domain	FN2_1	IGF2R MRC2	3.15e-03	14	113	2	PS00023
Domain	FN2	IGF2R MRC2	3.15e-03	14	113	2	SM00059
Domain	ABC_TRANSPORTER_1	ABCA4 ABCG2 ABCC2	3.24e-03	49	113	3	PS00211
Domain	ABC_transporter-like	ABCA4 ABCG2 ABCC2	3.44e-03	50	113	3	IPR003439
Domain	-	G6PC2 G6PC1	5.21e-03	18	113	2	1.20.144.10
Domain	acidPPc	G6PC2 G6PC1	5.21e-03	18	113	2	SM00014
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.28e-11	31	89	8	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.70e-11	32	89	8	M27455
Pathway	REACTOME_CARDIAC_CONDUCTION	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A ATP2B1	1.25e-07	130	89	9	M27454
Pathway	REACTOME_SENSORY_PERCEPTION_OF_TASTE	TAS2R5 SCN2A SCN3A SCN9A SCNN1B TAS2R20	4.66e-07	47	89	6	M42524
Pathway	REACTOME_MUSCLE_CONTRACTION	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A DMD ATP2B1	5.81e-07	203	89	10	M5485
Pathway	REACTOME_L1CAM_INTERACTIONS	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	9.23e-07	121	89	8	M872
Pathway	WP_ADHD_AND_AUTISM_ASD_PATHWAYS	GABRG1 ADORA2A RPTOR SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.90e-05	367	89	11	M48346
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH3 DNAH7 DNAH1 DNAH6	2.33e-05	27	89	4	M47755
Pathway	WP_DRAVET_SYNDROME	SCN1A SCN2A SCN3A SCN8A	2.71e-05	28	89	4	M45519
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH3 DNAH7 DNAH1 DNAH6	1.52e-04	43	89	4	M47669
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH3 DNAH7 DNAH1 DNAH6	1.81e-04	45	89	4	M47670
Pathway	BIOCARTA_LIS1_PATHWAY	DNAH3 DNAH1 DNAH6	2.19e-04	19	89	3	M22005
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.52e-19	9	121	8	16382098
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A SCNN1B	2.15e-17	13	121	8	15123669
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN3A SCN8A SCN9A SCN10A	1.56e-15	6	121	6	23652591
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A	1.30e-13	9	121	6	15746173
Pubmed	Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.	SCN2A SCN3A SCN4A SCN5A SCN8A	4.69e-13	5	121	5	17724025
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN3A SCN8A	1.39e-10	4	121	4	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN3A SCN8A	1.39e-10	4	121	4	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN3A SCN8A	1.39e-10	4	121	4	29578003
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN3A SCN5A SCN8A	3.64e-10	12	121	5	30175250
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN1A SCN2A SCN3A SCN9A	6.95e-10	5	121	4	8812438
Pubmed	Early development of electrical excitability in the mouse enteric nervous system.	SCN3A SCN5A SCN8A SCN9A	6.95e-10	5	121	4	22875929
Pubmed	Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.	SCN1A SCN4A SCN5A DMD	9.65e-09	8	121	4	9412493
Pubmed	Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.	SCN1A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A SCNN1B	3.27e-08	139	121	8	16985003
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN3A SCN9A	4.11e-08	3	121	3	19284629
Pubmed	Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).	SCN1A SCN3A SCN9A	4.11e-08	3	121	3	33895391
Pubmed	SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.	SCN1A SCN2A SCN3A	4.11e-08	3	121	3	23859570
Pubmed	Sodium channels SCN1A, SCN2A and SCN3A in familial autism.	SCN1A SCN2A SCN3A	4.11e-08	3	121	3	12610651
Pubmed	Abnormal expression of voltage-gated sodium channels Nav1.7, Nav1.3 and Nav1.8 in trigeminal neuralgia.	SCN3A SCN9A SCN10A	4.11e-08	3	121	3	19699781
Pubmed	Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.	SCN1A SCN2A SCN3A	4.11e-08	3	121	3	18784617
Pubmed	Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.	SCN1A SCN2A SCN3A	4.11e-08	3	121	3	17544618
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A SCN8A	4.11e-08	3	121	3	32845893
Pubmed	Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.	SCN4A SCN5A SCN9A	4.11e-08	3	121	3	20038812
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A SCN8A	4.11e-08	3	121	3	28518218
Pubmed	Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.	SCN1A SCN2A ABCC2	4.11e-08	3	121	3	25155934
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A SCN8A	4.11e-08	3	121	3	17928448
Pubmed	Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.	SCN1A SCN2A SCN3A	4.11e-08	3	121	3	14973256
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	ADGRB2 ADGRB3 ADGRV1 ADGRL4 CELSR1	1.03e-07	33	121	5	25713288
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH3 DNAH7 DNAH1 DNAH6	1.36e-07	14	121	4	9373155
Pubmed	Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.	SCN1A SCN9A SCN10A	1.64e-07	4	121	3	22260870
Pubmed	Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.	SCN1A SCN2A SCN3A	1.64e-07	4	121	3	35801810
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A SCN8A	1.64e-07	4	121	3	21156207
Pubmed	Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.	SCN1A SCN2A SCN3A	1.64e-07	4	121	3	8974318
Pubmed	Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.	SCN1A SCN2A SCN3A	4.09e-07	5	121	3	1679748
Pubmed	Primary Ciliary Dyskinesia Associated Disease-Causing Variants in CCDC39 and CCDC40 Cause Axonemal Absence of Inner Dynein Arm Heavy Chains DNAH1, DNAH6, and DNAH7.	DNAH7 DNAH1 DNAH6	4.09e-07	5	121	3	39056782
Pubmed	Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.	SCN1A SCN2A SCN3A	4.09e-07	5	121	3	24337656
Pubmed	Contactin regulates the current density and axonal expression of tetrodotoxin-resistant but not tetrodotoxin-sensitive sodium channels in DRG neurons.	SCN8A SCN9A SCN10A	8.15e-07	6	121	3	16029194
Pubmed	An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.	SCN3A SCN8A SCN10A	8.15e-07	6	121	3	23711479
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A SCN8A	1.42e-06	7	121	3	25818041
Pubmed	Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.	SCN1A SCN5A SCN8A	1.42e-06	7	121	3	15272007
Pubmed	Pain without nociceptors? Nav1.7-independent pain mechanisms.	SCN3A SCN9A SCN10A	1.42e-06	7	121	3	24440715
Pubmed	Significant determinants of mouse pain behaviour.	SCN3A SCN9A SCN10A	2.27e-06	8	121	3	25101983
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRB2 ADGRB3 ADGRV1 ADGRL4	3.09e-06	29	121	4	15203201
Pubmed	Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.	SCN1A SCN5A SCN8A	3.40e-06	9	121	3	17884088
Pubmed	Genetic mapping of the peripheral sodium channel genes, Scn9a and Scn10a, in the mouse.	SCN3A SCN9A SCN10A	3.40e-06	9	121	3	8854872
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	TMEM87A SLC6A8 LSR IGF2R KIDINS220 LATS2 GPR158 ABCC2 ATP2B1 PTTG1IP VAT1	5.15e-06	569	121	11	30639242
Pubmed	Integral and associated lysosomal membrane proteins.	DPP4 VPS39 SPG11 SIDT2 SPPL2A RPTOR	5.48e-06	126	121	6	17897319
Pubmed	Interrogating the protein interactomes of RAS isoforms identifies PIP5K1A as a KRAS-specific vulnerability.	TMEM214 TMEM87A SLC6A8 LSR TMEM161A IGF2R KIDINS220 DHCR7 ATP2B1 VAT1	5.80e-06	467	121	10	30194290
Pubmed	Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.	SCN1A SCN2A SCN3A	8.83e-06	12	121	3	8169823
Pubmed	A common genetic variant within SCN10A modulates cardiac SCN5A expression.	SCN5A SCN10A	1.20e-05	2	121	2	24642470
Pubmed	Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.	SCN2A SCN3A	1.20e-05	2	121	2	20346423
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	1.20e-05	2	121	2	37901435
Pubmed	State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.	SCN4A SCN9A	1.20e-05	2	121	2	18079277
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	1.20e-05	2	121	2	26410685
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	1.20e-05	2	121	2	10827969
Pubmed	Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein.	XPO1 DMD	1.20e-05	2	121	2	24486332
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	1.20e-05	2	121	2	19694741
Pubmed	Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.	SCN2A SCN8A	1.20e-05	2	121	2	35348308
Pubmed	Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.	SCN2A SCN3A	1.20e-05	2	121	2	11245985
Pubmed	Novel isoforms of the sodium channels Nav1.8 and Nav1.5 are produced by a conserved mechanism in mouse and rat.	SCN5A SCN10A	1.20e-05	2	121	2	15047701
Pubmed	Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.	SCN2A SCN8A	1.20e-05	2	121	2	15760941
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	1.20e-05	2	121	2	1317301
Pubmed	Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.	SCN2A SCN3A	1.20e-05	2	121	2	23016767
Pubmed	Voltage-gated sodium channel (SkM1) content in dystrophin-deficient muscle.	SCN4A DMD	1.20e-05	2	121	2	11316257
Pubmed	Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.	SCN2A SCN3A	1.20e-05	2	121	2	27153334
Pubmed	Expression of brain-specific angiogenesis inhibitor 2 (BAI2) in normal and ischemic brain: involvement of BAI2 in the ischemia-induced brain angiogenesis.	ADGRB2 ADGRB3	1.20e-05	2	121	2	12218411
Pubmed	Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.	SCN1A SCN3A	1.20e-05	2	121	2	24990319
Pubmed	Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.	SCN3A SCN9A	1.20e-05	2	121	2	25172946
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	1.20e-05	2	121	2	31439038
Pubmed	Small intestinal efflux mediated by MRP2 and BCRP shifts sulfasalazine intestinal permeability from high to low, enabling its colonic targeting.	ABCG2 ABCC2	1.20e-05	2	121	2	19541926
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	1.20e-05	2	121	2	31943325
Pubmed	Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.	SCN4A SCN5A	1.20e-05	2	121	2	11834499
Pubmed	Sigma-1 receptors modulate neonatal Nav1.5 ion channels in breast cancer cell lines.	SIGMAR1 SCN5A	1.20e-05	2	121	2	27160185
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	1.20e-05	2	121	2	15249644
Pubmed	Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.	SCN1A SCN3A	1.20e-05	2	121	2	27690330
Pubmed	Cloning and characterization of the human and rat islet-specific glucose-6-phosphatase catalytic subunit-related protein (IGRP) genes.	G6PC2 G6PC1	1.20e-05	2	121	2	11297555
Pubmed	Sodium channel slow inactivation interferes with open channel block.	SCN8A SCN9A	1.20e-05	2	121	2	27174182
Pubmed	Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.	SCN2A SCN8A	1.20e-05	2	121	2	18601978
Pubmed	Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.	SCN5A SCN10A	1.20e-05	2	121	2	24998131
Pubmed	Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.	SCN1A SCN3A	1.20e-05	2	121	2	23965409
Pubmed	Effect of ABCC2 and ABCG2 Gene Polymorphisms and CSF-to-Serum Albumin Ratio on Ceftriaxone Plasma and Cerebrospinal Fluid Concentrations.	ABCG2 ABCC2	1.20e-05	2	121	2	29873816
Pubmed	FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.	SCN2A SCN8A	1.20e-05	2	121	2	19465131
Pubmed	Isoform-specific effects of the beta2 subunit on voltage-gated sodium channel gating.	SCN2A SCN5A	1.20e-05	2	121	2	16847056
Pubmed	From GWAS to function: genetic variation in sodium channel gene enhancer influences electrical patterning.	SCN5A SCN10A	1.20e-05	2	121	2	24360055
Pubmed	SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.	SCN1A SCN2A	1.20e-05	2	121	2	30693367
Pubmed	Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.	SCN2A SCN8A	1.20e-05	2	121	2	23735284
Pubmed	Single nucleotide polymorphisms of SCN5A and SCN10A genes increase the risk of ventricular arrhythmias during myocardial infarction.	SCN5A SCN10A	1.20e-05	2	121	2	32330377
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	1.20e-05	2	121	2	29649454
Pubmed	The sigma-1 receptor binds to the Nav1.5 voltage-gated Na+ channel with 4-fold symmetry.	SIGMAR1 SCN5A	1.20e-05	2	121	2	22952230
Pubmed	Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5.	SCN5A SCN9A	1.20e-05	2	121	2	26861708
Pubmed	Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.	SCN9A SCN10A	1.20e-05	2	121	2	16111501
Pubmed	Metabolism, Transport and Drug-Drug Interactions of Silymarin.	ABCG2 ABCC2	1.20e-05	2	121	2	31615114
Pubmed	Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice.	USP34 ATM	1.20e-05	2	121	2	37043976
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	1.20e-05	2	121	2	33096315
Pubmed	Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.	SCN4A SCN5A	1.20e-05	2	121	2	30944319
Pubmed	Comparable clinical characteristics in Brugada syndrome patients harboring SCN5A or novel SCN10A variants.	SCN5A SCN10A	1.20e-05	2	121	2	31292628
Pubmed	Voltage-gated sodium channel modulation by sigma-receptors in cardiac myocytes and heterologous systems.	SIGMAR1 SCN5A	1.20e-05	2	121	2	19279232
Pubmed	Mutation in the neuronal voltage-gated sodium channel SCN1A in familial hemiplegic migraine.	SCN1A SCN5A	1.20e-05	2	121	2	16054936
Pubmed	Sodium channel expression within chronic multiple sclerosis plaques.	SCN2A SCN8A	1.20e-05	2	121	2	17805013
Pubmed	High ABCC2 and low ABCG2 gene expression are early events in the colorectal adenoma-carcinoma sequence.	ABCG2 ABCC2	1.20e-05	2	121	2	25793771
Pubmed	A systematic review and meta-analysis of the association of ABCC2/ABCG2 polymorphisms with antiepileptic drug responses in epileptic patients.	ABCG2 ABCC2	1.20e-05	2	121	2	34087576
Interaction	SCN11A interactions	SCN1A SCN5A SCN8A SCN9A SCN10A	1.46e-08	15	113	5	int:SCN11A
Interaction	SNTA1 interactions	ADGRB2 ADGRB3 SCN1A SCN4A SCN5A DMD ATP2B1	2.09e-06	105	113	7	int:SNTA1
Interaction	SCN5A interactions	SCN1A SCN5A SCN8A SCN9A SCN10A	6.45e-06	47	113	5	int:SCN5A
Interaction	LAMP2 interactions	GPR155 PTDSS1 SPG11 TMEM87A ADGRL4 SLC6A8 LSR SPPL2A IGF2R KIDINS220 RPTOR DHCR7 ATP2B1 VAT1	7.98e-06	609	113	14	int:LAMP2
Interaction	CACNA1D interactions	SCN1A SCN5A SCN9A SCN10A	9.13e-06	24	113	4	int:CACNA1D
Interaction	SCN4B interactions	SCN1A SCN2A SCN8A	9.42e-06	8	113	3	int:SCN4B
Interaction	NEDD4L interactions	CYP26B1 XPO1 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A SCNN1B	1.30e-05	320	113	10	int:NEDD4L
Interaction	SCN1A interactions	SCN1A SCN5A SCN9A SCN10A	2.00e-05	29	113	4	int:SCN1A
Interaction	SCN10A interactions	SCN1A SCN5A SCN10A	2.74e-05	11	113	3	int:SCN10A
Interaction	CACNA1B interactions	SIGMAR1 SCN1A SCN5A SCN9A	5.37e-05	37	113	4	int:CACNA1B
Interaction	NEDD4 interactions	POLR2B XPO1 LATS2 SCN1A SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A SCNN1B DMD	5.51e-05	544	113	12	int:NEDD4
Interaction	NALCN interactions	SCN1A SCN5A SCN9A	5.97e-05	14	113	3	int:NALCN
Interaction	CHP1 interactions	DPP4 ST7 XPO1 SLC6A8 SLC9A4	1.04e-04	83	113	5	int:CHP1
Cytoband	2q24.3	DPP4 SCN1A SCN2A G6PC2	8.15e-08	16	121	4	2q24.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2q24	DPP4 SCN1A SCN2A SCN3A SCN9A	2.30e-05	127	121	5	chr2q24
Cytoband	15q15.1	VPS39 PLA2G4E TMEM87A	2.66e-04	47	121	3	15q15.1
Cytoband	2q24	SCN3A SCN9A	3.73e-04	11	121	2	2q24
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	5.35e-19	9	75	8	1203
GeneFamily	Dyneins, axonemal	DNAH3 DNAH7 DNAH1 DNAH6	6.24e-07	17	75	4	536
GeneFamily	Adhesion G protein-coupled receptors, subfamily B	ADGRB2 ADGRB3	5.08e-05	3	75	2	912
GeneFamily	Glucose 6-phosphatases, catalytic	G6PC2 G6PC1	5.08e-05	3	75	2	1074
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	GPR155 CYP26B1 ADGRB2 ADGRB3 PI15 DNAH7 CELSR1 MRC2 SCN1A DHCR7 DNAI4 DNAH6 CCDC17	3.54e-06	600	119	13	M39055
Coexpression	HE_LIM_SUN_FETAL_LUNG_C4_ILC2_CELL	DPP4 SVOPL LSR NAMPT SCN2A TSPO LINC02694	5.73e-06	150	119	7	M45769
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 SFI1 ADGRV1 DNAH1 SCN2A PTPRQ SCN9A DMD	3.82e-08	184	120	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 SFI1 ADGRV1 DNAH1 SCN2A PTPRQ SCN9A DMD	3.82e-08	184	120	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 SFI1 ADGRV1 DNAH1 SCN2A PTPRQ SCN9A DMD	3.82e-08	184	120	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 ADGRV1 SCN1A PTPRQ SCN9A SCN10A ABCC2	1.37e-07	145	120	7	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	Healthy/Control-CD8+_T_naive\|World / Disease group and Cell class	DPP4 ZSWIM5 SFI1 SVOPL MRC2 DSEL TRAV20	2.46e-07	158	120	7	70680b29428b6bf882b1fae36f924b775961176b
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRG1 DNAH3 TMEM61 MFSD6L DNAH7 SCN9A SCNN1B	8.23e-07	189	120	7	cd4746ea6ae48a7dd14a2960d38d9445a738cf2c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 ADGRV1 DNAH7 CELSR1 SCN9A SCNN1B DMD	8.83e-07	191	120	7	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-MUC16+_ciliated\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 SLC44A4 DNAH7 CELSR1 DNAI4 DNAH6 CCDC17	9.80e-07	194	120	7	756082a0f5953b52229bb60d40b84701cb6cb23d
ToppCell	LPS_IL1RA-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	DNAH3 SLC44A4 DNAH7 DNAH1 SLC9A4 DNAI4 DNAH6	1.20e-06	200	120	7	4992dbf0514d674017315dbd20d91dfec0c608e9
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	SLC44A4 DNAH7 CELSR1 DNAI4 EMP2 DNAH6 CCDC17	1.20e-06	200	120	7	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DNAH3 TMEM61 MFSD6L ADGRL4 G6PC1	3.24e-06	84	120	5	f7ce09c6fb2795b7aecabce00cb9830b3c1a7d0e
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DNAH3 TMEM61 MFSD6L ADGRL4 G6PC1	3.24e-06	84	120	5	5d5e519a6652029b9f5275c8e648bbb123fd07b9
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	DNAH3 TMEM61 MFSD6L ADGRL4 G6PC1	3.24e-06	84	120	5	2b477de422a9f6a8474cba05094577b88236a4f0
ToppCell	Healthy/Control-CD8+_T_naive\|Healthy/Control / Disease group and Cell class	ZSWIM5 SFI1 SVOPL MRC2 DSEL TRAV20	4.81e-06	160	120	6	e1386c21fcbbf57fa32d8bdfba3cb1887477ff73
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRG1 ADGRV1 PTPRQ SCN9A SCN10A ABCC2	5.17e-06	162	120	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	7.53e-06	173	120	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GABRG1 ABCA4 CYP26B1 SLC5A4 SCN9A KCNH5	8.86e-06	178	120	6	5522b179c2e7dd707de01e2df10556349d0382a6
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAH1 DNAH6 CCDC17	8.86e-06	178	120	6	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LILRB3 PLA2G4E SCN3A ABCC2	9.29e-06	49	120	4	1002c6f5cfc09eb5cf882e0cf366d9ba8e456a57
ToppCell	390C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	LILRB3 PLA2G4E SCN3A ABCC2	9.29e-06	49	120	4	d7fc93efa70b464da39192e4bd8b1e8ad19bbec1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	9.44e-06	180	120	6	1f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCell	PCW_05-06-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	TMEM61 MFSD6L ADGRV1 SLC44A4 SCN3A NR0B2	1.01e-05	182	120	6	dc29e8735c3562ce32322351d28f7d9709208ebf
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.04e-05	183	120	6	b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell	367C-Epithelial_cells-Epithelial-F_(Ciliated)\|367C / Donor, Lineage, Cell class and subclass (all cells)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.04e-05	183	120	6	cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A4 SCN2A SCN3A SCNN1B LINC02694 NR0B2	1.07e-05	184	120	6	9690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.10e-05	185	120	6	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTSL1 ADGRV1 TMEM87A CELSR1 SCNN1B DMD	1.14e-05	186	120	6	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	COPD-Epithelial-Ciliated\|COPD / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.17e-05	187	120	6	f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GABRG1 DNAH3 SLC44A4 DNAH7 DNAH6 CCDC17	1.17e-05	187	120	6	e61992de4f98eeea08b43213850769d923f8db48
ToppCell	3'-Broncho-tracheal-Epithelial-Neuro-endocrine/ionocytic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEM61 MFSD6L SCN3A SCN9A SCNN1B KCNH5	1.21e-05	188	120	6	1f912ea015f50570e848259d948a0ba682d64bb4
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	USP34 GPR161 GPR158 SCN2A SCN3A SCN9A	1.21e-05	188	120	6	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	COPD-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.25e-05	189	120	6	3e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TMEM61 MFSD6L SIDT2 DHCR7 SCN9A SCNN1B	1.28e-05	190	120	6	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.32e-05	191	120	6	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.32e-05	191	120	6	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.32e-05	191	120	6	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TCAF2 ADAMTSL1 ADGRB3 ETS2 ADGRL4 ABCG2	1.36e-05	192	120	6	25cb6cc6cbf8dc20139d938adfc02ed7a8c3dfb6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 ADGRV1 DNAH7 CELSR1 SCN9A DMD	1.36e-05	192	120	6	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	IPF-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.36e-05	192	120	6	d903bbd6c18e29e2c4cdedeb3fea1fd5ad7baa11
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADGRB3 ADGRV1 KIDINS220 SCN5A SCN9A TSPO	1.36e-05	192	120	6	56f2388c9c4e19883ae5cff332c77f596ff744a8
ToppCell	COPD-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.36e-05	192	120	6	eab1105cd1a98cfcd3d74dc5c9b89e1799bba59e
ToppCell	IPF-Epithelial-Ciliated\|IPF / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.36e-05	192	120	6	354adc1354bf596fbc60dd45c0169688e6f45165
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.40e-05	193	120	6	e1b76102f812c433195d1e8811fdd3293a7bc22e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DNAH3 ADGRV1 DNAH7 CELSR1 DNAH6 CCDC17	1.40e-05	193	120	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Monocytes\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	LILRB3 ETS2 HCAR3 NAMPT TSPO ATP2B1	1.40e-05	193	120	6	ddbd8944661ac3b0b5fe63471bdc24ba05598017
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	DNAH3 DNAH7 DNAI4 DMD DNAH6 CCDC17	1.40e-05	193	120	6	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLAMF9 ETS2 XBP1 CELSR1 NAMPT ATP2B1	1.40e-05	193	120	6	b93f6af5999ad207fef5edc2bd900c7c6342f626
ToppCell	ASK440-Epithelial-Ciliated\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.40e-05	193	120	6	a0baa8be6f590b2031fede22be588715ae458e93
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.44e-05	194	120	6	3cd90d01ed5a5ce65aad8284dab2537ec16e3d7c
ToppCell	ASK440-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.44e-05	194	120	6	c84a7fa94fb06e08aae04db56c8c313b0afde1d7
ToppCell	Control-Epithelial-Ciliated\|World / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.44e-05	194	120	6	958e648138676d46698090b4046cb484083ae449
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTSL1 ADGRV1 DNAH7 CELSR1 SCN9A DMD	1.44e-05	194	120	6	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	0e763f36786515698b593e5c93f6a56619c1242d
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	581b04220587e1d5198b1abd6965965ace7803e7
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	93b1559382a12cfb158aa5fac7386e38b4f87989
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	79dc031258579ea328181dda33710dd897f1064a
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	db4270c135c392ed443670981656e3cd5b95939d
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	3e70ee987d66d450062d5df3d7c733ccc7344470
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 SLC44A4 DNAH7 DNAH1 DNAI4 DNAH6	1.49e-05	195	120	6	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.49e-05	195	120	6	6365e3893e38231090ec2dbef010dec71dea3d07
ToppCell	COVID-19-Epithelial-Ciliated_cells\|Epithelial / Condition, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.53e-05	196	120	6	de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM61 MFSD6L ADORA2A SCN9A SCNN1B G6PC1	1.53e-05	196	120	6	a4cc02ea41479d24044bd2ca6441f85d683c0ca9
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADGRB3 GPR158 SCN2A SCN3A SCN8A ATP2B1	1.53e-05	196	120	6	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMEM61 MFSD6L ADORA2A SCN9A SCNN1B G6PC1	1.53e-05	196	120	6	50aaca81b593ff71790bb75403b2e4c3ab03a6d2
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 CELSR1 DNAI4 DNAH6	1.53e-05	196	120	6	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	wk_20-22-Epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	DNAH3 SLC44A4 DNAH7 CELSR1 DNAH6 CCDC17	1.58e-05	197	120	6	468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	DNAH3 SLC44A4 DNAH7 EMP2 DNAH6 CCDC17	1.58e-05	197	120	6	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADGRB3 SCN1A SCN2A SCN3A SCN8A ATP2B1	1.62e-05	198	120	6	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Control_saline-Epithelial_airway\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 SLC44A4 DNAH7 DNAH1 CELSR1 DNAH6	1.62e-05	198	120	6	e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR158 SCN1A SCN2A SCN3A SCN8A ATP2B1	1.62e-05	198	120	6	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR158 SCN1A SCN2A SCN3A SCN8A ATP2B1	1.62e-05	198	120	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Control_saline-Epithelial_airway-airway_epithelial\|Control_saline / Treatment groups by lineage, cell group, cell type	DNAH3 SLC44A4 DNAH7 DNAH1 CELSR1 DNAH6	1.62e-05	198	120	6	e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCell	medial-Epithelial-Ciliated-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.67e-05	199	120	6	526002f16bbf61cf086278d45a401cc0b0b757a8
ToppCell	distal-Epithelial-Ciliated-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.67e-05	199	120	6	2de1fe124737a6cca4b3805ab3056f9d9d7c16c7
ToppCell	medial-Epithelial-Ciliated\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.67e-05	199	120	6	a2daa42b100c422dc8c04fb7d2ebf54293eef574
ToppCell	medial-2-Epithelial-Ciliated\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.67e-05	199	120	6	c02f04a5aa79ee0cf427f6e94b93ceab38ebbcd7
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC44A4 DNAH7 DNAH1 LSR CELSR1 SCNN1B	1.67e-05	199	120	6	60919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCell	LPS_anti-TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	DNAH3 DNAH7 DNAH1 SLC9A4 DNAI4 DNAH6	1.67e-05	199	120	6	15f7814b7074170eee7ccacaa670b1d128fc68bb
ToppCell	LPS_anti-TNF-Epithelial_airway\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SLC44A4 DNAH7 DNAH1 LSR CELSR1 SCNN1B	1.67e-05	199	120	6	6aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCell	Biopsy_Control_(H.)-Epithelial-Ciliated\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	9ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	DNAH3 SLC44A4 DNAH7 DNAH1 SLC9A4 DNAH6	1.72e-05	200	120	6	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	Biopsy_IPF-Epithelial-Differentiating_Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	SLC44A4 DNAH7 SCNN1B DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	8dfce65e417d6dcacb871d93d1539cdf807002fe
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH7 DNAH1 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	31d75c26055177d656df1fbb10b764cebd61e122
ToppCell	Biopsy_Other_PF-Epithelial-Ciliated\|Biopsy_Other_PF / Sample group, Lineage and Cell type	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	721371698bce8890853fb6b6b01a2c20293b39e9
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ABCA4 LSR CELSR1 PTPRQ SCNN1B DSEL	1.72e-05	200	120	6	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	5abd6d81e1cc354484ae693fcd708d78926e75b5
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	7cb3e3bd9e851ccb096e0a3471819471d85ebace
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 DNAH7 DNAH1 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	e1dce91c6c531bb212002a14705e496d77ad3490
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	9c9d2b0276c7b0709c2eeeb0673a2f58106fb14e
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	f1a49bc818054fb0734d3b84725ee6487b034567
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Ciliated\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	d7ae09189cf0b7e2f7e7fc6b0921975b75aa7d62
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Ciliated\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	8441e289377215a6877640946fe3f6de1f456502
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Ciliated-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	DNAH3 SLC44A4 DNAH7 DNAI4 DNAH6 CCDC17	1.72e-05	200	120	6	cf59110547cc66b5f4a2999735336b0309ba9b0d
ToppCell	Globus_pallidus\|World / BrainAtlas - Mouse McCarroll V32	GABRG1 ADCK5 TMEM86B SIDT2 SCN5A	2.34e-05	126	120	5	44b63f945d5bedf1a2ca1810e7e100276ea9dd89
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CCDC134 SETD4 SLC44A4 RPTOR SCN5A	2.62e-05	129	120	5	cbeeaa554da971ba2e4c4b82c85a1d070a45abb8
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	GABRG1 LATS2 SCN4A SCN9A VAT1	3.50e-05	137	120	5	5cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 PLA2G4E PTPRQ G6PC1 KCNH5	4.02e-05	141	120	5	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
Drug	APETx1, Anthopleura elegantissima	SCN2A SCN3A SCN4A SCN8A SCN10A	1.88e-11	6	116	5	ctd:C475726
Drug	Zonisamide	SCN1A SCN2A SCN3A SCN4A SCN5A SCN9A	1.81e-10	17	116	6	DB00909
Drug	disopyramide	HCAR3 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B NR0B2	1.60e-09	66	116	8	CID000003114
Drug	pentobarbital	GABRG1 SIGMAR1 ADORA2A HCAR3 SCN3A SCN4A SCN9A SCN10A TSPO SCNN1B PTTG1IP KCNH5	1.71e-09	224	116	12	CID000004737
Drug	carbamazepine	XBP1 ADORA2A SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A TSPO SCNN1B ABCG2	2.00e-09	179	116	11	CID000002554
Drug	pilsicainide	HCAR3 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	3.37e-09	46	116	7	CID000004820
Drug	AC1L1MOZ	SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	4.16e-09	27	116	6	CID000031958
Drug	tocainide	SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	8.25e-09	30	116	6	CID000038945
Drug	benzocaine	SCN2A SCN3A SCN4A SCN9A SCN10A SCNN1B	3.14e-08	37	116	6	CID000002337
Drug	diprafenone	SCN3A SCN4A SCN9A SCN10A SCNN1B	3.46e-08	19	116	5	CID000071249
Drug	tetradotoxin	GABRG1 SIGMAR1 ADORA2A HCAR3 KIDINS220 SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A TSPO SCNN1B	3.95e-08	428	116	14	CID000020382
Drug	2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate	SCN2A SCN3A SCN8A SCN10A	4.41e-08	8	116	4	ctd:C489827
Drug	spiradoline	SIGMAR1 SCN3A SCN4A SCN9A SCN10A SCNN1B	1.22e-07	46	116	6	CID000005620
Drug	N-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide	SCN3A SCN4A SCN9A	1.29e-07	3	116	3	ctd:C561228
Drug	lidocaine	GABRG1 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B DMD PTTG1IP	1.34e-07	160	116	9	CID000003676
Drug	AC1NT1AF	SCN3A SCN4A SCN9A SCN10A SCNN1B	1.54e-07	25	116	5	CID005322157
Drug	quindine	LILRB3 HCAR3 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B ABCG2 KCNH5	1.85e-07	219	116	10	CID000001065
Drug	Pirmenolum	SCN3A SCN4A SCN9A SCN10A SCNN1B	1.90e-07	26	116	5	CID000004853
Drug	verapamil	ABCA4 ADGRL4 HCAR3 RPTOR SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B ABCG2 ABCC2 ATP2B1 KCNH5	2.07e-07	490	116	14	CID000002520
Drug	PbTx-1	SCN3A SCN4A SCN9A SCN10A SCNN1B	2.32e-07	27	116	5	CID006437089
Drug	nefopam	SCN3A SCN4A SCN9A SCN10A SCNN1B	2.32e-07	27	116	5	CID000004450
Drug	Sodium	SCN2A SCN3A SCN5A SCN8A SCN9A SCN10A SCNN1B	2.43e-07	84	116	7	ctd:D012964
Drug	bepridil	LATS2 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B ATP2B1	2.71e-07	126	116	8	CID000002351
Drug	paraben	SCN3A SCN4A SCN9A SCN10A SCNN1B	2.82e-07	28	116	5	CID000007175
Drug	strychnine HCl	GABRG1 ADGRV1 HCAR3 SCN3A SCN4A SCN9A SCN10A TSPO SCNN1B	3.82e-07	181	116	9	CID000005304
Drug	NSC7524	ADORA2A HCAR3 SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	4.00e-07	182	116	9	CID000005657
Drug	Lidocaine	SCN5A SCN9A SCN10A	5.14e-07	4	116	3	DB00281
Drug	APETx2 protein, Anthopleura elegantissima	SCN2A SCN8A SCN10A	5.14e-07	4	116	3	ctd:C501880
Drug	NSC93767	SCN3A SCN4A SCN9A SCN10A SCNN1B	5.68e-07	32	116	5	CID000005658
Drug	propofol	GABRG1 HCAR3 SCN3A SCN4A SCN9A SCN10A TSPO SCNN1B DMD	6.00e-07	191	116	9	CID000004943
Drug	propafenone	CYP26B1 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	7.01e-07	98	116	7	CID000004932
Drug	5-hydroxypropafenone	SCN3A SCN4A SCN9A SCN10A SCNN1B	7.78e-07	34	116	5	CID000107927
Drug	AC1L1W4O	SCN4A SCN9A TSPO SCNN1B	8.36e-07	15	116	4	CID000036625
Drug	saxitoxin	SCN2A SCN3A SCN4A SCN9A SCN10A SCNN1B	9.93e-07	65	116	6	CID000037165
Drug	AC1L1CQC	SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	9.93e-07	65	116	6	CID000002012
Drug	mexiletine	SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	1.09e-06	66	116	6	CID000004178
Drug	dibucaine	SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	1.30e-06	68	116	6	CID000003025
Drug	aprindine	SCN3A SCN4A SCN9A SCN10A SCNN1B	1.38e-06	38	116	5	CID000002218
Drug	GBR 12909	SIGMAR1 SCN3A SCN4A SCN9A SCN10A SCNN1B	1.42e-06	69	116	6	CID000003455
Drug	amiodarone	SIGMAR1 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B ABCG2	1.67e-06	160	116	8	CID000002156
Drug	flecainide	SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	1.68e-06	71	116	6	CID000003355
Drug	isoflurane	GABRG1 HCAR3 SCN3A SCN4A SCN9A SCN10A SCNN1B DMD ATP2B1 PTTG1IP	1.69e-06	279	116	10	CID000003763
Drug	Tetrodotoxin	SCN2A SCN3A SCN5A SCN8A SCN9A	1.80e-06	40	116	5	ctd:D013779
Drug	S-ropivacaine	SCN3A SCN4A SCN9A SCN10A SCNN1B	1.80e-06	40	116	5	CID000071273
Drug	moricizine	SCN4A SCN5A SCN9A SCNN1B	1.85e-06	18	116	4	CID000034632
Drug	Scorpion Venoms	SCN2A SCN3A SCN4A SCN9A	1.85e-06	18	116	4	ctd:D012604
Drug	lamotrigine	SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	2.19e-06	116	116	7	CID000003878
Drug	diphenhydramine	SCN3A SCN4A SCN9A SCN10A SCNN1B ATM	2.32e-06	75	116	6	CID000003100
Drug	fenpropathrin	SCN2A SCN3A SCN10A	2.55e-06	6	116	3	ctd:C044267
Drug	riluzole	GABRG1 SCN3A SCN4A SCN5A SCN9A SCN10A TSPO SCNN1B	3.12e-06	174	116	8	CID000005070
Drug	bupivacaine	SIGMAR1 SCN3A SCN4A SCN9A SCN10A SCNN1B DMD	3.61e-06	125	116	7	CID000002474
Drug	bupropion	HCAR3 SCN3A SCN4A SCN9A SCN10A SCNN1B	3.65e-06	81	116	6	CID000000444
Drug	epicholesterol	ABCA4 GPX7 ADGRL4 HCAR3 LSR NAMPT FDPS DHCR7 TSPO G6PC2 ABCC2 ATP2B1 G6PC1 NR0B2	4.49e-06	636	116	14	CID000000304
Drug	indoxacarb	SCN3A SCN4A SCN9A SCN10A SCNN1B	5.02e-06	49	116	5	CID000107720
Drug	glufosfamide	SLC5A4 GBA3 ABCG2 ABCC2	7.45e-06	25	116	4	CID000123628
Drug	Multicide	SCN2A SCN4A SCN9A SCNN1B	7.45e-06	25	116	4	CID000024365
Drug	ketamine	GABRG1 SIGMAR1 HCAR3 DHCR7 SCN3A SCN4A SCN9A SCN10A SCNN1B	8.05e-06	262	116	9	CID000003821
Drug	AC1NSN3X	SCN3A SCN4A SCN9A SCN10A SCNN1B	8.16e-06	54	116	5	CID005366189
Drug	Mexiletine	SCN5A SCN9A SCN10A	1.06e-05	9	116	3	ctd:D008801
Drug	triamterene	SCN3A SCN4A SCN9A SCN10A SCNN1B	1.16e-05	58	116	5	CID000005546
Drug	encainide	SCN4A SCN5A SCN9A SCNN1B	1.19e-05	28	116	4	CID000048040
Drug	DPI 201-106	SCN4A SCN5A SCN9A SCNN1B	1.19e-05	28	116	4	CID000005190
Drug	procaine	GABRG1 HCAR3 SCN3A SCN4A SCN9A SCN10A SCNN1B	1.36e-05	153	116	7	CID000004914
Drug	oxcarbazepine	SCN4A SCN5A SCN9A SCNN1B	1.58e-05	30	116	4	CID000034312
Drug	zonisamide	SCN3A SCN4A SCN9A SCN10A SCNN1B	1.62e-05	62	116	5	CID000005734
Drug	phenytoin	SIGMAR1 SCN2A SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	1.68e-05	219	116	8	CID000001775
Drug	pyraclofos	SCN2A SCN4A SCN5A SCN9A SCNN1B KCNH5	1.73e-05	106	116	6	CID000093460
Drug	dofetilide	SCN4A SCN5A SCN9A SCNN1B KCNH5	1.75e-05	63	116	5	CID000071329
Drug	dihydrochloride	SIGMAR1 DHCR7 SCN3A SCN4A SCN9A SCN10A SCNN1B	1.75e-05	159	116	7	CID000070978
Drug	RH-3421	SCN4A SCN9A SCNN1B	2.06e-05	11	116	3	CID000108039
Drug	chloroacetylajmaline	SCN4A SCN9A SCNN1B	2.06e-05	11	116	3	CID000038681
Drug	resiniferatoxin	SCN3A SCN4A SCN9A SCN10A SCNN1B	2.20e-05	66	116	5	CID000104826
Drug	orange dye	GBA3 DMD	2.57e-05	2	116	2	CID000217048
Drug	Hexylcaine	SCN5A SCN10A	2.57e-05	2	116	2	DB00473
Drug	Ranolazine	SCN5A SCN9A	2.57e-05	2	116	2	DB00243
Drug	Phenytoin	SCN1A SCN5A	2.57e-05	2	116	2	DB00252
Drug	Flecainide	SCN4A SCN5A	2.57e-05	2	116	2	DB01195
Drug	mu-conotoxin KIIIA, Conus kinoshitai	SCN2A SCN4A	2.57e-05	2	116	2	ctd:C502265
Drug	gabapentin	GABRG1 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	2.59e-05	169	116	7	CID000003446
Drug	NSC15627	SCN4A SCN5A SCN9A SCNN1B	2.64e-05	34	116	4	CID000002073
Drug	Ro 22-9194	SCN4A SCN9A SCNN1B	2.74e-05	12	116	3	CID000129209
Drug	T2755	SCN3A SCN4A SCN9A SCN10A SCNN1B	3.13e-05	71	116	5	CID000005514
Drug	Pyrethroids	SCN4A SCN9A TSPO SCNN1B ATP2B1	3.13e-05	71	116	5	CID000005053
Drug	AC1LCJM3	SCN4A SCN9A SCNN1B	3.55e-05	13	116	3	CID000631640
Drug	CID6432355	SCN4A SCN9A SCNN1B	3.55e-05	13	116	3	CID006432355
Drug	sotalol	SCN4A SCN5A SCN9A SCNN1B NR0B2	3.59e-05	73	116	5	CID000005253
Drug	fenfluramine	ABCA4 SCN3A SCN4A SCN9A SCN10A SCNN1B DSEL	3.61e-05	178	116	7	CID000003337
Drug	sipatrigine	SCN2A SCN4A SCN9A SCNN1B	3.71e-05	37	116	4	CID000060803
Drug	1, 3-diallylurea	SCN3A SCN4A SCN9A SCN10A SCNN1B	3.83e-05	74	116	5	CID000074537
Drug	imide	SCN3A SCN4A SCN9A SCN10A SCNN1B	3.83e-05	74	116	5	CID000443040
Drug	isofagomine	SCN4A SCN5A SCN9A SCN10A SCNN1B	4.09e-05	75	116	5	CID000447607
Drug	lorcainide	SCN4A SCN9A SCNN1B	4.50e-05	14	116	3	CID000042883
Drug	octylguanidine	SCN4A SCN9A SCNN1B	4.50e-05	14	116	3	CID000030621
Drug	robinetin	ABCG2 ABCC2 NR0B2	4.50e-05	14	116	3	CID005281692
Drug	ranolazine	SCN4A SCN5A SCN9A SCNN1B	4.58e-05	39	116	4	CID000056959
Drug	procainamide	HCAR3 SCN3A SCN4A SCN5A SCN9A SCN10A SCNN1B	5.47e-05	190	116	7	CID000004913
Drug	trimethyloxonium	SCN4A SCN9A SCNN1B	5.61e-05	15	116	3	CID000093245
Drug	nonanol	SCN2A SCN4A ABCC2	5.61e-05	15	116	3	CID000008914
Drug	QX-222	HCAR3 SCN4A SCN9A SCNN1B	6.17e-05	42	116	4	CID000005014
Drug	QX-314	GABRG1 SCN4A SCN5A SCN9A SCNN1B	6.28e-05	82	116	5	CID000003925
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.86e-18	10	115	8	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	1.86e-18	10	115	8	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A	2.03e-17	12	115	8	DOID:0060170 (implicated_via_orthology)
Disease	epilepsy (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN4A SCN5A SCN8A SCN9A SCN10A KCNH5	1.64e-08	163	115	9	DOID:1826 (implicated_via_orthology)
Disease	Generalized Epilepsy with Febrile Seizures Plus	ADGRV1 SCN1A SCN2A SCN9A	2.72e-08	9	115	4	C3502809
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A SCN3A SCN9A	1.52e-06	22	115	4	DOID:2030 (implicated_via_orthology)
Disease	Ventricular Dysfunction	ADORA2A IGF2R DMD	3.18e-06	8	115	3	C0242973
Disease	Early Infantile Epileptic Encephalopathy 6	SCN1A SCN9A	1.51e-05	2	115	2	C4551549
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A SCN9A	1.60e-05	13	115	3	C0751122
Disease	Colorectal Carcinoma	DNAH3 ABCA4 SETD4 SLC44A4 NAMPT SCNN1B ABCG2 DMD ABCC2 DSEL NLRP8 ZNF292	1.98e-05	702	115	12	C0009402
Disease	B Virus Infection	SCN8A SCN9A	4.51e-05	3	115	2	C0037140
Disease	Benign familial infantile epilepsy	SCN2A SCN8A	4.51e-05	3	115	2	cv:C5575231
Disease	Postherpetic neuralgia	SCN8A SCN9A	4.51e-05	3	115	2	C0032768
Disease	Herpesviridae Infections	SCN8A SCN9A	4.51e-05	3	115	2	C0019372
Disease	Primary Erythermalgia	SCN9A SCN10A	4.51e-05	3	115	2	C0014805
Disease	Juvenile amyotrophic lateral sclerosis	SIGMAR1 SPG11	4.51e-05	3	115	2	cv:C3468114
Disease	PAROXYSMAL EXTREME PAIN DISORDER	SCN9A SCN10A	4.51e-05	3	115	2	C1833661
Disease	status epilepticus (biomarker_via_orthology)	SLC6A8 ABCG2 ATM DMD ABCC2	4.62e-05	100	115	5	DOID:1824 (biomarker_via_orthology)
Disease	Epilepsy	SCN1A SCN2A SCN8A SCN9A KCNH5	6.97e-05	109	115	5	C0014544
Disease	Brugada ECG Pattern	SCN5A SCN10A	8.99e-05	4	115	2	C1721096
Disease	orotidine measurement	NUP85 ABCG2	8.99e-05	4	115	2	EFO_0800630
Disease	Juvenile amyotrophic lateral sclerosis	SIGMAR1 SPG11	8.99e-05	4	115	2	C3468114
Disease	urate measurement, bone density	ADGRB3 ETS2 SLC44A4 FADS2B FBXL4 DNAH1 KIDINS220 LATS2 G6PC1 KCNH5	1.59e-04	619	115	10	EFO_0003923, EFO_0004531
Disease	renal overload-type gout	SPATA31C2 ABCG2	2.24e-04	6	115	2	EFO_0021525
Disease	Familial benign neonatal epilepsy	SCN2A SCN8A	2.24e-04	6	115	2	C0220669
Disease	glycocholenate sulfate measurement	ADCK5 ABCC2	2.24e-04	6	115	2	EFO_0800276
Disease	presubiculum volume	DPP4 ADAMTSL1 HRK	2.39e-04	31	115	3	EFO_0009400
Disease	attention deficit hyperactivity disorder, bipolar disorder	ADGRL4 SCN2A LINC02694	2.39e-04	31	115	3	EFO_0003888, MONDO_0004985
Disease	Malignant neoplasm of breast	ABCA4 VPS39 ZSWIM5 ETS2 XBP1 TMEM161A FBXO8 SCNN1B ABCG2 ATM DMD G6PC1 NLRP8	2.89e-04	1074	115	13	C0006142
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	3.12e-04	7	115	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	3.12e-04	7	115	2	C0751057
Disease	electrocardiography, PR interval	SCN5A SCN10A	3.12e-04	7	115	2	EFO_0004327, EFO_0004462
Disease	Congenital Pain Insensitivity	SCN9A SCN10A	3.12e-04	7	115	2	C0002768
Disease	Hereditary Sensory Autonomic Neuropathy, Type 5	SCN9A SCN10A	3.12e-04	7	115	2	C0020075
Disease	metabolite measurement	SVOPL GBA3 IGF2R FDPS ABCG2 G6PC2 DMD ABCC2 HAO2	3.55e-04	560	115	9	EFO_0004725
Disease	sex interaction measurement, Crohn's disease	USP34 XPO1 LINC02694	4.07e-04	37	115	3	EFO_0000384, EFO_0008343
Disease	Cataract	DHCR7 ATM ATP2B1	4.07e-04	37	115	3	C0086543
Disease	Early Childhood Epilepsy, Myoclonic	SCN1A SCN9A	4.15e-04	8	115	2	C0393695
Disease	Idiopathic Myoclonic Epilepsy	SCN1A SCN9A	4.15e-04	8	115	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	SCN1A SCN9A	4.15e-04	8	115	2	C0338479
Disease	Benign Infantile Myoclonic Epilepsy	SCN1A SCN9A	4.15e-04	8	115	2	C0751120
Disease	hypokalemic periodic paralysis (implicated_via_orthology)	SCN4A SCNN1B	4.15e-04	8	115	2	DOID:14452 (implicated_via_orthology)
Disease	Myoclonic Encephalopathy	SCN1A SCN9A	4.15e-04	8	115	2	C0438414
Disease	Myoclonic Absence Epilepsy	SCN1A SCN9A	4.15e-04	8	115	2	C0393703
Disease	Neurodevelopmental Disorders	SCN1A SCN2A SCN8A ZNF292	4.89e-04	93	115	4	C1535926
Disease	Inherited neuropathies	SPG11 SCN9A ATM	5.13e-04	40	115	3	C0598589
Disease	Tremor, Neonatal	ADORA2A SCN8A	5.32e-04	9	115	2	C0235843
Disease	Febrile Convulsions	SCN1A SCN2A	5.32e-04	9	115	2	C0009952
Disease	Tremor, Perioral	ADORA2A SCN8A	5.32e-04	9	115	2	C0235078
Disease	Nerve Tremors	ADORA2A SCN8A	5.32e-04	9	115	2	C0235083
Disease	Tremor, Limb	ADORA2A SCN8A	5.32e-04	9	115	2	C0235081
Disease	Tremor, Muscle	ADORA2A SCN8A	5.32e-04	9	115	2	C0235082
Disease	Senile Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0149840
Disease	Pill Rolling Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0751564
Disease	Tremor, Semirhythmic	ADORA2A SCN8A	5.32e-04	9	115	2	C0751565
Disease	Action Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234376
Disease	Passive Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234377
Disease	Static Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234378
Disease	Resting Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234379
Disease	Intermittent Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234372
Disease	Fine Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234373
Disease	Coarse Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234374
Disease	Massive Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234375
Disease	Persistent Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234370
Disease	Continuous Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234371
Disease	Darkness Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0234381
Disease	Involuntary Quiver	ADORA2A SCN8A	5.32e-04	9	115	2	C1527384
Disease	Saturnine Tremor	ADORA2A SCN8A	5.32e-04	9	115	2	C0040827
Disease	Myoclonic Epilepsy	SCN1A SCN9A	5.32e-04	9	115	2	C0014550
Disease	supraventricular ectopy	SCN5A SCN10A	5.32e-04	9	115	2	EFO_0009277
Disease	Bipolar Disorder	GABRG1 MCHR2 XBP1 HCAR3 SCN2A SCN8A TSPO LINC02694	5.75e-04	477	115	8	C0005586
Disease	Epilepsy, Myoclonic, Infantile	SCN1A SCN9A	6.64e-04	10	115	2	C0917800
Disease	Tremor	ADORA2A SCN8A	8.09e-04	11	115	2	C0040822
Disease	Myoclonic Astatic Epilepsy	SCN1A SCN9A	8.09e-04	11	115	2	C0393702
Disease	Cardiomyopathy, Dilated	SCN5A ATM DMD	8.78e-04	48	115	3	C0007193
Disease	Prenatal Exposure Delayed Effects	SIGMAR1 ATM	9.69e-04	12	115	2	C0033054
Disease	Squamous cell carcinoma of the head and neck	NAMPT ABCG2 ABCC2	1.11e-03	52	115	3	C1168401
Disease	Brugada Syndrome 1	SCN5A SCN10A	1.14e-03	13	115	2	C4551804
Disease	nervous system disorder	SCN8A ABCG2 ABCC2	1.17e-03	53	115	3	C0027765
Disease	T wave morphology measurement	SCN5A SCN10A	1.33e-03	14	115	2	EFO_0008398
Disease	MMR-related febrile seizures	SCN1A SCN2A	1.53e-03	15	115	2	EFO_0006519
Disease	P wave duration	SCN5A SCN10A	1.53e-03	15	115	2	EFO_0005094
Disease	Seizures	SIGMAR1 FBXL4 ADORA2A ABCC2 ZNF292	1.67e-03	218	115	5	C0036572
Disease	Neuralgia, Supraorbital	SCN9A SCN10A	1.74e-03	16	115	2	C0038870
Disease	Neuralgia	SCN9A SCN10A	1.74e-03	16	115	2	C0027796
Disease	Romano-Ward Syndrome	SCN5A SCN10A	1.74e-03	16	115	2	C0035828
Disease	Neuralgia, Atypical	SCN9A SCN10A	1.74e-03	16	115	2	C0234247
Disease	Neuralgia, Stump	SCN9A SCN10A	1.74e-03	16	115	2	C0234249
Disease	Neuralgia, Iliohypogastric Nerve	SCN9A SCN10A	1.74e-03	16	115	2	C0423712
Disease	Neuralgia, Perineal	SCN9A SCN10A	1.74e-03	16	115	2	C0423711
Disease	Paroxysmal Nerve Pain	SCN9A SCN10A	1.74e-03	16	115	2	C0751373
Disease	Nerve Pain	SCN9A SCN10A	1.74e-03	16	115	2	C0751372
Disease	Neuralgia, Ilioinguinal	SCN9A SCN10A	1.74e-03	16	115	2	C0751371
Disease	Neuralgia, Vidian	SCN9A SCN10A	1.74e-03	16	115	2	C0042656
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	1.74e-03	16	115	2	C0393706
Disease	Intellectual Disability	SRD5A3 SLC6A8 SCN1A DHCR7 SCN3A SCN8A ZNF292	1.88e-03	447	115	7	C3714756
Disease	Amyotrophic lateral sclerosis	SIGMAR1 SPG11	1.97e-03	17	115	2	cv:C0002736
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	ATP2B1 ZNF292	1.97e-03	17	115	2	DOID:0060307 (is_implicated_in)
Disease	breast carcinoma (is_marker_for)	IGF2R ABCG2 ATM	2.21e-03	66	115	3	DOID:3459 (is_marker_for)
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	2.21e-03	18	115	2	HP_0002373

Protein segments in the cluster

Peptide	Gene	Start	Entry
VCWLSTENNFIWSFI	ADGRL4	561	Q9HBW9
FCWVLTEAWQSYLAV	ADGRB2	1011	O60241
SLVCELQVWQGLAWA	CCDC17	471	Q96LX7
VSNAVIWCTWFLDSF	ABCA4	691	P78363
ILGNVLVCWAVWLNS	ADORA2A	21	P29274
FFLASFCWVLTEAWQ	ADGRB3	951	O60242
VNLTTIASWLSWLQY	ABCG2	556	Q9UNQ0
CLLWNQAAASWLSDS	ADGRV1	5856	Q8WXG9
QISLDYWWCTNVVLR	ADCK5	96	Q3MIX3
WTLLWAACAQSLDLN	CCDC142	306	Q17RM4
QSLIWSWDQGFCQAL	CCDC142	361	Q17RM4
EWWLVNVACIRTGII	ACSM4	126	P0C7M7
DFCWLSLQDTLIWSF	CELSR1	2601	Q9NYQ6
WQRLTEEQCLFSAWL	DMD	561	P11532
EAWLDNFARCWDNLV	DMD	641	P11532
TIIFDNWIPLLWCAN	DHCR7	171	Q9UBM7
LAVLTFTLCSVVIWW	CDC14C	421	A4D256
FSCSELSIEQWLWSI	ATP2B1	1031	P20020
NKVCNWLVISSWLAG	OR6C65	136	A6NJZ3
GLAFVLNCRTWWQVL	KIDINS220	701	Q9ULH0
LNCRTWWQVLDSLLN	KIDINS220	706	Q9ULH0
TQLCDWWSVGVILFE	LATS2	891	Q9NRM7
WWQDLCSVFATNDKL	NLRP8	691	Q86W28
ANLSSCLWWLFNQEP	GPR155	671	Q7Z3F1
VVFWFLIGWTSSVCQ	GPR158	536	Q5T848
DSLQRAWTVGWCVEL	FDPS	146	P14324
AWTVGWCVELLQAFF	FDPS	151	P14324
LAVSQQLWQLRWAAT	CYP26B1	26	Q9NR63
NVVWLLVATILSCGW	KIAA1109	26	Q2LD37
CAFKTTWDWVILILT	KCNH5	211	Q8NCM2
ACNQQLCVEWAFSSW	ADAMTSL1	1601	Q8N6G6
QILSAISNRALWWAV	MFSD6L	461	Q8IWD5
IKECSIALSNWWFVA	NUP85	361	Q9BW27
VCQWLLWATNEFSLV	ETS2	111	P15036
CVWQDLANDELLWQG	FBXO8	96	Q9NRD0
WAQAQRICTWFQAEL	MRC2	846	Q9UBG0
CDVTWATQERISLQW	DPP4	301	P27487
RQWCVQKNSWFLSLF	ABCC2	121	Q92887
VTLLCQSWWQFDTFL	LILRB3	341	O75022
CEFNRSWLQIGIVSW	PRSS38	251	A1L453
VQWLQCCLESFWSLE	NR0B2	146	Q15466
LTLINCTSDFVWLKW	PTPRQ	1291	Q9UMZ3
LQRYWVCFSLQDITW	FADS2B	326	A8MWK0
IISVLWNGFLLWCLT	SRD5A3	81	Q9H8P0
WNGFLLWCLTQSLFL	SRD5A3	86	Q9H8P0
TWWLVVTNVFFNQAL	SRD5A3	276	Q9H8P0
LWSSIFSLNLLDAWN	PLA2G4E	576	Q3MJ16
ASCWNTSAELLNKSW	MCHR2	6	Q969V1
QEVLEEWLNCQRSWL	DNAH1	1231	Q9P2D7
PSLVNCCTIDWFNEW	DNAH1	2731	Q9P2D7
AALLFIATVDNAWWV	EMP2	16	P54851
WCEISQQQWLELFSV	ATM	156	Q13315
WLTCQRNWLYLESIF	DNAH6	1101	Q9C0G6
PSLINCCTIDWFQSW	DNAH3	2581	Q8TD57
LQVYCAWSLLDNFEW	GBA3	411	Q9H227
CILTVVLSWVSFWIN	GABRG1	281	Q8N1C3
QSRCTLVQWLNLSWT	FBXL4	341	Q9UKA2
WLGFWAVQLNVCLSR	G6PC1	156	P35575
ALVNCCTIDWFQSWP	DNAH7	2491	Q8WXX0
SFLWSVFWLIQISVC	G6PC2	151	Q9NQR9
WAAVAAGLWVLCTVI	IFNL4	6	K9M1U5
LSCSADWGVIIWQQE	DNAI4	721	Q5VTH9
REWIFGVVWCNFSAL	GPR161	91	Q8N6U8
FWTLNWVLALGQCVL	SLC44A4	451	Q53GD3
VAAAWLLLWAAACAQ	GPX7	6	Q96SL4
TLLFAALVCWQWGIF	SCNN1B	56	P51168
LWFIELLDVWSTCSQ	DSEL	811	Q8IZU8
AVVFVWLLLSTWCTA	LSR	71	Q86X29
NLVVNCWVLGFIWFL	OR11G2	181	Q8NGC1
WLCAAAQVAALAAWL	HRK	71	O00198
LNWECVVSFLWNTEA	IGF2R	906	P11717
LKQTFLSVLWQVTCW	TAS2R20	286	P59543
VTVLQIYFCDWQQAW	SFI1	316	A8K8P3
ETSSWVNLVLWCVVL	TMEM179B	166	Q7Z7N9
SFYLLTVLLACWENW	SIDT2	306	Q8NBJ9
QLSIAWASVLWFNLL	STAT2	461	P52630
LSWSQETTKTWCVFN	SPATA31C2	286	B4DYI2
AWCWLDFLIVDVSII	SCN4A	1096	P35499
LAYLIWWTAACQLLA	TMEM161A	451	Q9NX61
LCDWNVWTALETYLQ	TCAF2	821	A6NFQ2
LQWRQVSWITCWIAL	LRTM2	16	Q8N967
TSLCWNDLSWFQSIT	HAO2	201	Q9NYQ3
NWTAAIISCLLWGIT	HCAR3	141	P49019
WCWLDFLIVDVSLVS	SCN5A	1271	Q14524
NAWCWLDFLIVDVSL	SCN9A	1256	Q15858
WNWAFICFTLAFCQI	SLC9A4	381	Q6AI14
VLTQVVWLWLGTQSF	SIGMAR1	21	Q99720
LWQEACWIVISSYFD	POLR2B	21	P30876
IFSYSALLWAWCTVN	SETD4	191	Q9NVD3
ALLWAWCTVNTRAVY	SETD4	196	Q9NVD3
TALWYWCTNQVIVQR	SLC5A4	286	Q9NY91
CYWLTNWIETILVQS	NAMPT	141	P43490
LQIQSLISCWAFWTT	XBP1	196	P17861
SLSWCWNAEDVVAFV	WDR17	131	Q8IZU2
TTLLWQAFWECVVVA	SLC6A8	481	P48029
AWCWLDFLIVDVSLV	SCN3A	1271	Q9NY46
AWCQTSDFITVAWLI	MRGPRX1	171	Q96LB2
TGFLEQLKSCIVWSW	ST7	6	Q9NRC1
WVAICLGRIWQNFDS	RPTOR	576	Q8N122
RCEWQLENWQVALVT	SVOPL	76	Q8N434
TNAWCWLDFLIVDVS	SCN1A	1281	P35498
WNLLIRWGISFCNQT	CCDC134	136	Q9H6E4
RQCWVQGNAWISCIT	LINC02694	96	Q8NAA6
LNWALWWDQLTQESI	SPG11	851	Q96JI7
VVLVAGTLCFAWWSE	TMEM61	26	Q8N0U2
LSIFWVLVSQASLWF	TAS2R5	81	Q9NYW4
WKNLNTLCWAIGSIS	XPO1	491	O14980
SCWLQQLQKWSDLDV	ZSWIM5	436	Q9P217
ECAFIVLWLQLGWLS	TRAV20	6	A0A0B4J274
WDLLICQELLNFFIW	SAGE2P	411	A6NJ88
NAWCWLDFLIVNISL	SCN10A	1216	Q9Y5Y9
RWAWILQDILGIAFC	SPPL2A	311	Q8TCT8
TNAWCWLDFLIVDVS	SCN2A	1271	Q99250
EAWPTLCSAQVAAWF	TMEM102	256	Q8N9M5
WTWLCLQDITVAFLD	TMEM214	666	Q6NUQ4
CAWELTLFWSKLQQR	ZNF292	291	O60281
EFCIARWWASLSDVN	TPP2	731	P29144
TNAWCWLDFLIVAVS	SCN8A	1261	Q9UQD0
ARWGVCWVNFEALII	PTTG1IP	86	P53801
FCLWIPEDQLSWFAA	TMEM86B	36	Q8N661
LWRWCGSEEVVAVLQ	SLAMF9	21	Q96A28
LARTWWNQFSVTALQ	VAT1	301	Q99536
NLAKSAEAWAATCIW	PI15	96	O43692
QESWTVWQLDCLACL	USP34	1511	Q70CQ2
GASFLVLWLQLCWVS	TRAV23DV6	6	A0A075B6W5
LLPNFAECWWDQVIL	PTDSS1	206	P48651
LAWLAFTTTLNYCVW	TSPO	141	P30536
DTALCWWIFISLTQT	TMEM87A	371	Q8NBN3
LQIDCLAAWEEWLLV	VPS39	16	Q96JC1
WWLVNTAALIIACFP	VN1R2	346	Q8NFZ6