Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein kinase activity	JAK2 TNK1 ERBB4 TTBK1 PDGFRA MTOR CSNK2A1 GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.27e-06	600	84	13	GO:0004672
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	JAK2 TNK1 ERBB4 TTBK1 PDGFRA MTOR POLD1 CSNK2A1 POLR2A GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3 TRRAP	1.57e-06	938	84	16	GO:0016772
GeneOntologyMolecularFunction	kinase activity	JAK2 TNK1 ERBB4 TTBK1 PDGFRA MTOR CSNK2A1 GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3 TRRAP	3.38e-06	764	84	14	GO:0016301
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	JAK2 TNK1 ERBB4 TTBK1 PDGFRA MTOR CSNK2A1 GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	7.84e-06	709	84	13	GO:0016773
GeneOntologyMolecularFunction	dihydrofolic acid binding	DHFR DHFR2	5.23e-05	3	84	2	GO:0051871
GeneOntologyMolecularFunction	dihydrofolate reductase activity	DHFR DHFR2	5.23e-05	3	84	2	GO:0004146
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	AASS DHFR DHFR2	5.60e-05	18	84	3	GO:0016646
GeneOntologyMolecularFunction	protein serine kinase activity	TTBK1 MTOR CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.45e-04	363	84	8	GO:0106310
GeneOntologyMolecularFunction	DNA exonuclease activity, producing 5'-phosphomonoesters	MRE11 DCLRE1C POLD1	1.54e-04	25	84	3	GO:0016895
GeneOntologyMolecularFunction	DNA exonuclease activity	MRE11 DCLRE1C POLD1	1.74e-04	26	84	3	GO:0004529
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH group of donors	AASS DHFR DHFR2	2.69e-04	30	84	3	GO:0016645
GeneOntologyMolecularFunction	protein tyrosine kinase activity	JAK2 TNK1 ERBB4 TTBK1 PDGFRA	3.67e-04	145	84	5	GO:0004713
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TTBK1 MTOR CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	5.75e-04	446	84	8	GO:0004674
GeneOntologyMolecularFunction	guanylate cyclase activity	GUCY1A2 GUCY2D	7.70e-04	10	84	2	GO:0004383
GeneOntologyMolecularFunction	phosphatidylinositol 3-kinase binding	JAK2 PDGFRA DNM2	7.85e-04	43	84	3	GO:0043548
GeneOntologyMolecularFunction	single-stranded DNA endodeoxyribonuclease activity	MRE11 DCLRE1C	1.32e-03	13	84	2	GO:0000014
GeneOntologyMolecularFunction	3'-5'-DNA exonuclease activity	MRE11 POLD1	2.02e-03	16	84	2	GO:0008296
GeneOntologyMolecularFunction	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	MRE11 DCLRE1C POLD1	2.27e-03	62	84	3	GO:0016796
GeneOntologyMolecularFunction	mRNA regulatory element binding translation repressor activity	DHFR DHFR2	2.28e-03	17	84	2	GO:0000900
GeneOntologyMolecularFunction	platelet-derived growth factor receptor binding	PDGFRA VEGFA	2.28e-03	17	84	2	GO:0005161
GeneOntologyMolecularFunction	DNA nuclease activity	MRE11 DCLRE1C POLD1	2.83e-03	67	84	3	GO:0004536
GeneOntologyMolecularFunction	sequence-specific mRNA binding	DHFR DHFR2	2.85e-03	19	84	2	GO:1990825
GeneOntologyMolecularFunction	folic acid binding	DHFR DHFR2	3.16e-03	20	84	2	GO:0005542
GeneOntologyMolecularFunction	extracellular matrix binding	POLR2A ADAMTS15 VEGFA	3.61e-03	73	84	3	GO:0050840
GeneOntologyMolecularFunction	tau-protein kinase activity	TTBK1 SIK3	3.82e-03	22	84	2	GO:0050321
GeneOntologyMolecularFunction	cyclase activity	GUCY1A2 GUCY2D	4.54e-03	24	84	2	GO:0009975
GeneOntologyMolecularFunction	phosphorus-oxygen lyase activity	GUCY1A2 GUCY2D	4.93e-03	25	84	2	GO:0016849
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC14 ZDHHC3	5.32e-03	26	84	2	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC14 ZDHHC3	5.32e-03	26	84	2	GO:0019707
GeneOntologyMolecularFunction	NADPH binding	DHFR DHFR2	5.32e-03	26	84	2	GO:0070402
GeneOntologyMolecularFunction	growth factor receptor binding	JAK2 ERBB4 PDGFRA VEGFA	6.13e-03	173	84	4	GO:0070851
GeneOntologyBiologicalProcess	protein autophosphorylation	JAK2 TNK1 MRE11 ERBB4 PDGFRA MTOR CSNK2A1 SIK2 VEGFA	3.40e-07	228	83	9	GO:0046777
GeneOntologyBiologicalProcess	positive regulation of glial cell differentiation	TTBK1 TENM4 MTOR RNF112 HDAC1	3.94e-06	59	83	5	GO:0045687
GeneOntologyBiologicalProcess	positive regulation of nervous system development	TGM2 TTBK1 TENM4 MTOR GLI3 RNF112 HDAC1 AMIGO2 VEGFA	4.62e-05	418	83	9	GO:0051962
GeneOntologyBiologicalProcess	positive regulation of gliogenesis	TTBK1 TENM4 MTOR RNF112 HDAC1	4.73e-05	98	83	5	GO:0014015
GeneOntologyBiologicalProcess	response to methotrexate	DHFR DHFR2	4.79e-05	3	83	2	GO:0031427
GeneOntologyBiologicalProcess	VEGF-activated platelet-derived growth factor receptor signaling pathway	PDGFRA VEGFA	4.79e-05	3	83	2	GO:0038086
GeneOntologyBiologicalProcess	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	PDGFRA VEGFA	4.79e-05	3	83	2	GO:0038091
GeneOntologyBiologicalProcess	muscle cell proliferation	JAK2 TGM2 ERBB4 TENM4 MTOR GLI1 HDAC1 VEGFA	5.37e-05	329	83	8	GO:0033002
GeneOntologyBiologicalProcess	regulation of glial cell differentiation	TTBK1 TENM4 MTOR RNF112 HDAC1	6.29e-05	104	83	5	GO:0045685
GeneOntologyBiologicalProcess	positive regulation of neurogenesis	TGM2 TTBK1 TENM4 MTOR GLI3 RNF112 HDAC1 VEGFA	8.95e-05	354	83	8	GO:0050769
GeneOntologyBiologicalProcess	dihydrofolate metabolic process	DHFR DHFR2	9.55e-05	4	83	2	GO:0046452
GeneOntologyBiologicalProcess	positive regulation of peptidyl-tyrosine phosphorylation	JAK2 ERBB4 PDGFRA MTOR SRCIN1 VEGFA	1.29e-04	193	83	6	GO:0050731
GeneOntologyBiologicalProcess	positive regulation of molecular function	JAK2 MRE11 TGM2 RTKN2 ERBB4 TTBK1 PDGFRA MTOR DHFR DHFR2 ARID5B NR1H3 SRCIN1 SPAG8 RALGAPA2 HDAC1	1.61e-04	1430	83	16	GO:0044093
GeneOntologyBiologicalProcess	polyol biosynthetic process	ISYNA1 DHFR DHFR2 PLCD1	1.73e-04	69	83	4	GO:0046173
GeneOntologyBiologicalProcess	platelet-derived growth factor receptor signaling pathway	JAK2 PDGFRA ARID5B VEGFA	1.93e-04	71	83	4	GO:0048008
GeneOntologyBiologicalProcess	positive regulation of smooth muscle cell proliferation	JAK2 TGM2 MTOR HDAC1 VEGFA	2.38e-04	138	83	5	GO:0048661
GeneOntologyBiologicalProcess	positive regulation of oligodendrocyte differentiation	TENM4 MTOR HDAC1	3.44e-04	34	83	3	GO:0048714
GeneOntologyBiologicalProcess	peptidyl-tyrosine phosphorylation	JAK2 ERBB4 TTBK1 PDGFRA MTOR SRCIN1 VEGFA	3.50e-04	327	83	7	GO:0018108
GeneOntologyBiologicalProcess	cardiac muscle tissue development	ERBB4 TENM4 NRAP PDGFRA MTOR GLI1 VEGFA	3.50e-04	327	83	7	GO:0048738
GeneOntologyBiologicalProcess	regulation of gliogenesis	TTBK1 TENM4 MTOR RNF112 HDAC1	3.61e-04	151	83	5	GO:0014013
GeneOntologyBiologicalProcess	peptidyl-tyrosine modification	JAK2 ERBB4 TTBK1 PDGFRA MTOR SRCIN1 VEGFA	3.63e-04	329	83	7	GO:0018212
GeneOntologyCellularComponent	GLI-SUFU complex	GLI1 GLI3	9.07e-05	4	82	2	GO:1990788
GeneOntologyCellularComponent	protein kinase CK2 complex	CSNK2A1 CSNK2A3	9.07e-05	4	82	2	GO:0005956
GeneOntologyCellularComponent	nuclear chromosome	MRE11 POLD1 CSNK2A1 NOL6 TRRAP HDAC1	4.91e-04	254	82	6	GO:0000228
Domain	Kinase-like_dom	JAK2 TNK1 ERBB4 TTBK1 PDGFRA MTOR CSNK2A1 GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3 TRRAP DNM2	1.68e-08	542	84	15	IPR011009
Domain	Protein_kinase_ATP_BS	JAK2 TNK1 ERBB4 TTBK1 PDGFRA CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.03e-06	379	84	11	IPR017441
Domain	Prot_kinase_dom	JAK2 TNK1 ERBB4 TTBK1 PDGFRA CSNK2A1 GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.85e-06	489	84	12	IPR000719
Domain	PROTEIN_KINASE_DOM	JAK2 TNK1 ERBB4 TTBK1 PDGFRA CSNK2A1 GUCY2D MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	2.02e-06	493	84	12	PS50011
Domain	PROTEIN_KINASE_ATP	JAK2 TNK1 ERBB4 TTBK1 PDGFRA CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	6.47e-06	459	84	11	PS00107
Domain	DHFR_dom	DHFR DHFR2	2.00e-05	2	84	2	IPR001796
Domain	DHFR_2	DHFR DHFR2	2.00e-05	2	84	2	PS51330
Domain	-	DHFR DHFR2	2.00e-05	2	84	2	3.40.430.10
Domain	DHFR_1	DHFR DHFR2	2.00e-05	2	84	2	PF00186
Domain	DHFR-like_dom	DHFR DHFR2	2.00e-05	2	84	2	IPR024072
Domain	Pept_M12B_ADAM-TS8	ADAMTS15 ADAMTS8	2.00e-05	2	84	2	IPR013277
Domain	DHFR_1	DHFR DHFR2	2.00e-05	2	84	2	PS00075
Domain	DHFR	DHFR DHFR2	2.00e-05	2	84	2	IPR012259
Domain	S_TKc	TTBK1 PDGFRA CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	2.11e-04	359	84	8	SM00220
Domain	Pkinase_Tyr	JAK2 TNK1 ERBB4 PDGFRA GUCY2D	2.90e-04	129	84	5	PF07714
Domain	FAT	MTOR TRRAP	2.96e-04	6	84	2	PS51189
Domain	FATC	MTOR TRRAP	2.96e-04	6	84	2	PS51190
Domain	HNOB_dom_associated	GUCY1A2 GUCY2D	2.96e-04	6	84	2	IPR011645
Domain	FAT	MTOR TRRAP	2.96e-04	6	84	2	PF02259
Domain	HNOBA	GUCY1A2 GUCY2D	2.96e-04	6	84	2	PF07701
Domain	PIK-rel_kinase_FAT	MTOR TRRAP	2.96e-04	6	84	2	IPR003151
Domain	FATC_dom	MTOR TRRAP	2.96e-04	6	84	2	IPR003152
Domain	PIK_FAT	MTOR TRRAP	2.96e-04	6	84	2	IPR014009
Domain	FATC	MTOR TRRAP	2.96e-04	6	84	2	SM01343
Domain	Ser-Thr/Tyr_kinase_cat_dom	JAK2 TNK1 ERBB4 PDGFRA GUCY2D	3.96e-04	138	84	5	IPR001245
Domain	TyrKc	JAK2 TNK1 ERBB4 PDGFRA	6.66e-04	88	84	4	SM00219
Domain	Tyr_kinase_cat_dom	JAK2 TNK1 ERBB4 PDGFRA	6.66e-04	88	84	4	IPR020635
Domain	PROTEIN_KINASE_TYR	JAK2 TNK1 ERBB4 PDGFRA	9.60e-04	97	84	4	PS00109
Domain	Tyr_kinase_AS	JAK2 TNK1 ERBB4 PDGFRA	9.60e-04	97	84	4	IPR008266
Domain	Ser/Thr_kinase_AS	TTBK1 CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.13e-03	357	84	7	IPR008271
Domain	PROTEIN_KINASE_ST	TTBK1 CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.22e-03	362	84	7	PS00108
Domain	Pkinase	TTBK1 CSNK2A1 MYLK4 SIK2 CAMK1G SIK3 CSNK2A3	1.64e-03	381	84	7	PF00069
Domain	-	MTOR TRRAP	2.30e-03	16	84	2	1.10.1070.11
Domain	PI3Kc	MTOR TRRAP	2.30e-03	16	84	2	SM00146
Domain	A/G_cyclase_CS	GUCY1A2 GUCY2D	2.60e-03	17	84	2	IPR018297
Domain	PI3/4_kinase_cat_dom	MTOR TRRAP	2.92e-03	18	84	2	IPR000403
Domain	PI3_PI4_kinase	MTOR TRRAP	2.92e-03	18	84	2	PF00454
Domain	PI3_4_KINASE_3	MTOR TRRAP	2.92e-03	18	84	2	PS50290
Domain	Nucleotide_cyclase	GUCY1A2 GUCY2D	2.92e-03	18	84	2	IPR029787
Domain	PI3_4_KINASE_1	MTOR TRRAP	2.92e-03	18	84	2	PS00915
Domain	PI3_4_KINASE_2	MTOR TRRAP	2.92e-03	18	84	2	PS00916
Domain	-	GUCY1A2 GUCY2D	2.92e-03	18	84	2	3.30.70.1230
Domain	GUANYLATE_CYCLASE_1	GUCY1A2 GUCY2D	3.25e-03	19	84	2	PS00452
Domain	Guanylate_cyc	GUCY1A2 GUCY2D	3.25e-03	19	84	2	PF00211
Domain	GUANYLATE_CYCLASE_2	GUCY1A2 GUCY2D	3.25e-03	19	84	2	PS50125
Domain	A/G_cyclase	GUCY1A2 GUCY2D	3.25e-03	19	84	2	IPR001054
Domain	CYCc	GUCY1A2 GUCY2D	3.25e-03	19	84	2	SM00044
Domain	Ca/CaM-dep_Ca-dep_prot_Kinase	MYLK4 SIK2 CAMK1G	3.71e-03	69	84	3	IPR020636
Pubmed	Combinatorial CRISPR-Cas9 screens for de novo mapping of genetic interactions.	JAK2 PDGFRA MTOR DHFR HDAC1 VEGFA	2.25e-08	71	85	6	28319113
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	MRE11 MLF2 DDX46 IPO8 COPG1 MTOR POLD1 POLR2A RRM1 CSNK2A3 DNM2 HDAC1	5.09e-08	638	85	12	33239621
Pubmed	Pleiotropy in FOXC1-attributable phenotypes involves altered ciliation and cilia-dependent signaling.	PDGFRA GLI1 GLI3	2.80e-07	6	85	3	39217245
Pubmed	Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3.	GLI1 GLI3 HDAC1	4.90e-07	7	85	3	12435627
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF711 TTC7A MRE11 ERBB4 POLD1 CSNK2A1 GLI3 POLR2A RNF213 SDF4 SIK3 RALGAPA2 TRRAP HDAC1	5.15e-07	1116	85	14	31753913
Pubmed	Gli1 is not required for Pdgfralpha expression during mouse embryonic development.	PDGFRA GLI1 GLI3	7.82e-07	8	85	3	15811134
Pubmed	The Sonic Hedgehog-Gli pathway regulates dorsal brain growth and tumorigenesis.	PDGFRA GLI1 GLI3	1.17e-06	9	85	3	11748155
Pubmed	Fusion of lung lobes and vessels in mouse embryos heterozygous for the forkhead box f1 targeted allele.	GLI1 GLI3 VEGFA	1.67e-06	10	85	3	11943666
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	TGM2 TTBK1 CSNK2A1 POLR2A ADAMTS15 CAMK1G ADAMTS8 SIK3 ALG1 DNM2 HDAC1	1.68e-06	730	85	11	34857952
Pubmed	Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity.	PDGFRA DHFR DHFR2	2.29e-06	11	85	3	28496133
Pubmed	Phospholipase C-delta1 and oxytocin receptor signalling: evidence of its role as an effector.	TGM2 PLCD1	5.90e-06	2	85	2	9512491
Pubmed	Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3.	GLI1 GLI3	5.90e-06	2	85	2	18559511
Pubmed	High-Throughput Implementation of the NanoBRET Target Engagement Intracellular Kinase Assay to Reveal Differential Compound Engagement by SIK2/3 Isoforms.	SIK2 SIK3	5.90e-06	2	85	2	31849250
Pubmed	A three-part signal governs differential processing of Gli1 and Gli3 proteins by the proteasome.	GLI1 GLI3	5.90e-06	2	85	2	21921029
Pubmed	Expression and alternative splicing of N-RAP during mouse skeletal muscle development.	NRAP NOL6	5.90e-06	2	85	2	18792955
Pubmed	Palmar and plantar pads and flexion creases of genetic polydactyly mice (Pdn).	GLI1 GLI3	5.90e-06	2	85	2	9918099
Pubmed	Vascular endothelial growth factor A as predictive marker for mTOR inhibition in relapsing high-grade serous ovarian cancer.	MTOR VEGFA	5.90e-06	2	85	2	27090655
Pubmed	Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes.	SIK2 SIK3	5.90e-06	2	85	2	27807598
Pubmed	Salt-inducible kinases (SIKs) regulate TGFβ-mediated transcriptional and apoptotic responses.	SIK2 SIK3	5.90e-06	2	85	2	31969556
Pubmed	Clinical and molecular prognostic factors in renal cell carcinoma: what we know so far.	MTOR VEGFA	5.90e-06	2	85	2	21763972
Pubmed	Interactions of G(h)/transglutaminase with phospholipase Cdelta1 and with GTP.	TGM2 PLCD1	5.90e-06	2	85	2	10518533
Pubmed	Anticancer effect of rapamycin on MCF-7 via downregulation of VEGF expression.	MTOR VEGFA	5.90e-06	2	85	2	26427711
Pubmed	The interaction of heparan sulfate proteoglycans with endothelial transglutaminase-2 limits VEGF165-induced angiogenesis.	TGM2 VEGFA	5.90e-06	2	85	2	26175493
Pubmed	Association of variants in FRAP1 and PDGFRA with corneal curvature in Asian populations from Singapore.	PDGFRA MTOR	5.90e-06	2	85	2	21665993
Pubmed	Podocytes, signaling pathways, and vascular factors in diabetic kidney disease.	MTOR VEGFA	5.90e-06	2	85	2	24780459
Pubmed	Assignment of casein kinase 2 alpha sequences to two different human chromosomes.	CSNK2A1 CSNK2A3	5.90e-06	2	85	2	1577469
Pubmed	Expression of the GLI family genes is associated with tumor progression in advanced lung adenocarcinoma.	GLI1 GLI3	5.90e-06	2	85	2	25103784
Pubmed	PDGFRA in vascular adventitial MSCs promotes neointima formation in arteriovenous fistula in chronic kidney disease.	PDGFRA GLI1	5.90e-06	2	85	2	33001865
Pubmed	Human dihydrofolate reductase is a substrate of protein kinase CK2α.	CSNK2A1 DHFR	5.90e-06	2	85	2	30961929
Pubmed	Pro-Apoptotic Activity of Ruxolitinib Alone and in Combination with Hydroxyurea, Busulphan, and PI3K/mTOR Inhibitors in JAK2-Positive Human Cell Lines.	JAK2 MTOR	5.90e-06	2	85	2	25931349
Pubmed	Molecular cloning and expression pattern of a Cubitus interruptus homologue from the mulberry silkworm Bombyx mori.	GLI1 GLI3	5.90e-06	2	85	2	12351188
Pubmed	Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.	CSNK2A1 CSNK2A3	5.90e-06	2	85	2	14646071
Pubmed	GLI1 overexpression promotes gastric cancer cell proliferation and migration and induces drug resistance by combining with the AKT-mTOR pathway.	MTOR GLI1	5.90e-06	2	85	2	30841479
Pubmed	The Evolution of Systemic Therapy in Metastatic Renal Cell Carcinoma.	MTOR VEGFA	5.90e-06	2	85	2	27249692
Pubmed	Gli3 is a Key Factor in the Schwann Cells from Both Intact and Injured Peripheral Nerves.	GLI1 GLI3	5.90e-06	2	85	2	32114096
Pubmed	Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.	CSNK2A1 CSNK2A3	5.90e-06	2	85	2	12860116
Pubmed	Hedgehog-regulated processing of Gli3 produces an anterior/posterior repressor gradient in the developing vertebrate limb.	GLI1 GLI3	5.90e-06	2	85	2	10693759
Pubmed	Safety and Efficacy of Vorinostat Plus Sirolimus or Everolimus in Patients with Relapsed Refractory Hodgkin Lymphoma.	MTOR HDAC1	5.90e-06	2	85	2	33055173
Pubmed	Chronic intermittent hypoxia increases β cell mass and activates the mammalian target of rapamycin/hypoxia inducible factor 1/vascular endothelial growth factor A pathway in mice pancreatic islet.	MTOR VEGFA	5.90e-06	2	85	2	23786956
Pubmed	ADAMTS8 and ADAMTS15 expression predicts survival in human breast carcinoma.	ADAMTS15 ADAMTS8	5.90e-06	2	85	2	16152618
Pubmed	gli, a zinc finger transcription factor and oncogene, is expressed during normal mouse development.	GLI1 GLI3	5.90e-06	2	85	2	8364225
Pubmed	A novel extracellular role for tissue transglutaminase in matrix-bound VEGF-mediated angiogenesis.	TGM2 VEGFA	5.90e-06	2	85	2	24052076
Pubmed	Inhibition of CK2α down-regulates Hedgehog/Gli signaling leading to a reduction of a stem-like side population in human lung cancer cells.	GLI1 CSNK2A1	5.90e-06	2	85	2	22768056
Pubmed	Molecular cloning of the human casein kinase II alpha subunit.	CSNK2A1 CSNK2A3	5.90e-06	2	85	2	2752008
Pubmed	Prevalence and clinical significance of mammalian target of rapamycin phosphorylation (p-mTOR) and vascular endothelial growth factor (VEGF) in clear cell carcinoma of the ovary.	MTOR VEGFA	5.90e-06	2	85	2	23464458
Pubmed	Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.	CSNK2A1 CSNK2A3	5.90e-06	2	85	2	8420794
Pubmed	ADAMTS8 inhibited lung cancer progression through suppressing VEGFA.	ADAMTS8 VEGFA	5.90e-06	2	85	2	35149432
Pubmed	KIF7 Controls the Proliferation of Cells of the Respiratory Airway through Distinct Microtubule Dependent Mechanisms.	PDGFRA GLI1 GLI3	6.28e-06	15	85	3	26439735
Pubmed	Stage-specific regulation of oligodendrocyte development by Wnt/β-catenin signaling.	PDGFRA GLI1 GLI3	9.35e-06	17	85	3	24948802
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	MLF2 ISYNA1 COPG1 AASS POLD1 POLR2A DHFR SDF4 RRM1 NDUFA9 ALG1 DNM2 HDAC1	1.11e-05	1257	85	13	37317656
Pubmed	Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis.	GLI1 GLI3 HDAC1	1.12e-05	18	85	3	14645126
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	JAK2 MRE11 ADO COPG1 RNF112 POLR2A ARID5B ADAMTS15 RNF213 HDAC1	1.27e-05	736	85	10	29676528
Pubmed	Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development.	PDGFRA GLI1 GLI3	1.33e-05	19	85	3	24886827
Pubmed	Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach.	COPG1 AASS POLD1 POLR2A TRRAP HDAC1	1.36e-05	211	85	6	17314511
Pubmed	Patterning of ventral telencephalon requires positive function of Gli transcription factors.	PDGFRA GLI1 GLI3	1.56e-05	20	85	3	19632216
Pubmed	Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.	COPG1 POLD1 POLR2A RRM1	1.66e-05	62	85	4	26508657
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	JAK2 POLD1 GUCY2D SEC24B EPX DNM2 HDAC1	1.67e-05	329	85	7	17474147
Pubmed	Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.	CSNK2A1 CSNK2A3	1.77e-05	3	85	2	15684395
Pubmed	Fuzzy modeling reveals a dynamic self-sustaining network of the GLI transcription factors controlling important metabolic regulators in adult mouse hepatocytes.	GLI1 GLI3	1.77e-05	3	85	2	26010061
Pubmed	Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma.	MTOR VEGFA	1.77e-05	3	85	2	19121088
Pubmed	Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.	CSNK2A1 CSNK2A3	1.77e-05	3	85	2	2174700
Pubmed	Identification of JAK2 as a mediator of FIP1L1-PDGFRA-induced eosinophil growth and function in CEL.	JAK2 PDGFRA	1.77e-05	3	85	2	22523564
Pubmed	mirna-383-5p Functions as an Anti-oncogene in Glioma through the Akt/mTOR Signaling Pathway by Targeting VEGFA.	MTOR VEGFA	1.77e-05	3	85	2	37592783
Pubmed	Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr.	DHFR DHFR2	1.77e-05	3	85	2	26830229
Pubmed	Genome-wide association study supports the role of the immunological system and of the neurodevelopmental processes in response to haloperidol treatment.	RTKN2 ARID5B	1.77e-05	3	85	2	24751813
Pubmed	Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.	DHFR DHFR2	1.77e-05	3	85	2	21402147
Pubmed	Substrate stiffening promotes VEGF-A functions via the PI3K/Akt/mTOR pathway.	MTOR VEGFA	1.77e-05	3	85	2	34823219
Pubmed	Transcription of the vascular endothelial growth factor gene in macrophages is regulated by liver X receptors.	NR1H3 VEGFA	1.77e-05	3	85	2	14699103
Pubmed	Transgenic mice expressing the tyr22 variant of murine DHFR: protection of transgenic marrow transplant recipients from lethal doses of methotrexate.	DHFR DHFR2	1.77e-05	3	85	2	9357973
Pubmed	Brachyphalangy, an allele of extra-toes in the mouse.	GLI1 GLI3	1.77e-05	3	85	2	5806166
Pubmed	Crystallization and preliminary characterization of crystals of human protein kinase CK2.	CSNK2A1 CSNK2A3	1.77e-05	3	85	2	11092945
Pubmed	Structure of amplified normal and variant dihydrofolate reductase genes in mouse sarcoma S180 cells.	DHFR DHFR2	1.77e-05	3	85	2	6282858
Pubmed	Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.	CSNK2A1 CSNK2A3	1.77e-05	3	85	2	12102635
Pubmed	BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.	MTOR VEGFA	1.77e-05	3	85	2	12393646
Pubmed	Acute iodine deficiency induces a transient VEGF-dependent microvascular response in mammary glands involving HIF-1, ROS, and mTOR.	MTOR VEGFA	1.77e-05	3	85	2	30020826
Pubmed	Gli family members are differentially expressed during the mitotic phase of spermatogenesis.	GLI1 GLI3	1.77e-05	3	85	2	9178901
Pubmed	The former annotated human pseudogene dihydrofolate reductase-like 1 (DHFRL1) is expressed and functional.	DHFR DHFR2	1.77e-05	3	85	2	21876184
Pubmed	Transcriptional regulation of the dihydrofolate reductase/rep-3 locus.	DHFR DHFR2	1.77e-05	3	85	2	7987046
Pubmed	Salt-inducible Kinases Are Critical Determinants of Female Fertility.	SIK2 SIK3	1.77e-05	3	85	2	32343771
Pubmed	Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3.	GLI1 GLI3	1.77e-05	3	85	2	10075717
Pubmed	New polymorphic markers in the vicinity of the pearl locus on mouse chromosome 13.	DHFR DHFR2	1.77e-05	3	85	2	8903722
Pubmed	Protein kinase CK2 regulates the dimerization of histone deacetylase 1 (HDAC1) and HDAC2 during mitosis.	CSNK2A1 HDAC1	1.77e-05	3	85	2	23612983
Pubmed	The expression of p-mTOR and COUP-TFII correlates with increased lymphangiogenesis and lymph node metastasis in prostate adenocarcinoma.	MTOR VEGFA	1.77e-05	3	85	2	29544697
Pubmed	Cortical fast-spiking parvalbumin interneurons enwrapped in the perineuronal net express the metallopeptidases Adamts8, Adamts15 and Neprilysin.	ADAMTS15 ADAMTS8	1.77e-05	3	85	2	25510509
Pubmed	Isolation and characterization of a variant dihydrofolate reductase cDNA from methotrexate-resistant murine L5178Y cells.	DHFR DHFR2	1.77e-05	3	85	2	2263462
Pubmed	mTOR, VEGF, PDGFR, and c-kit signaling pathway activation in Kaposi sarcoma.	MTOR VEGFA	1.77e-05	3	85	2	28506734
Pubmed	Unique and complimentary activities of the Gli transcription factors in Hedgehog signaling.	GLI1 GLI3	1.77e-05	3	85	2	16571352
Pubmed	Regulation of growth hormone induced JAK2 and mTOR signalling by hepatic protein tyrosine phosphatase 1B.	JAK2 MTOR	1.77e-05	3	85	2	24948418
Pubmed	Regulatory role of dynamin-2 in VEGFR-2/KDR-mediated endothelial signaling.	DNM2 VEGFA	1.77e-05	3	85	2	16049137
Pubmed	Salt-inducible kinase 3 deficiency exacerbates lipopolysaccharide-induced endotoxin shock accompanied by increased levels of pro-inflammatory molecules in mice.	SIK2 SIK3	1.77e-05	3	85	2	25619259
Pubmed	Unbalanced growth in mouse cells with amplified dhfr genes.	DHFR DHFR2	1.77e-05	3	85	2	9650531
Pubmed	Structure and genomic organization of the mouse dihydrofolate reductase gene.	DHFR DHFR2	1.77e-05	3	85	2	6244105
Pubmed	Hedgehog and Platelet-derived Growth Factor Signaling Intersect during Postnatal Lung Development.	PDGFRA GLI1	1.77e-05	3	85	2	36693140
Pubmed	Adipose-Derived VEGF-mTOR Signaling Promotes Endometrial Hyperplasia and Cancer: Implications for Obese Women.	MTOR VEGFA	1.77e-05	3	85	2	29133593
Pubmed	Constitutive Activation of mTORC1 in Endothelial Cells Leads to the Development and Progression of Lymphangiosarcoma through VEGF Autocrine Signaling.	MTOR VEGFA	1.77e-05	3	85	2	26777415
Pubmed	Retinal pigment epithelium cells produce VEGF in response to oxidized phospholipids through mechanisms involving ATF4 and protein kinase CK2.	CSNK2A1 VEGFA	1.77e-05	3	85	2	24021586
Pubmed	Selective multiplication of dihydrofolate reductase genes in methotrexate-resistant variants of cultured murine cells.	DHFR DHFR2	1.77e-05	3	85	2	627542
Pubmed	In vitro mutations in dihydrofolate reductase that confer resistance to methotrexate: potential for clinical application.	DHFR DHFR2	1.77e-05	3	85	2	9554740
Pubmed	Delphinidin inhibits angiogenesis through the suppression of HIF-1α and VEGF expression in A549 lung cancer cells.	MTOR VEGFA	1.77e-05	3	85	2	27959445
Pubmed	Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma.	GLI1 HDAC1	1.77e-05	3	85	2	28276480
Interaction	HSP90AA1 interactions	JAK2 TNK1 MRE11 FBXO40 MLF2 ERBB4 DDX46 GUCY1A2 MTOR AASS GLI1 WDR87 CSNK2A1 GUCY2D MYLK4 NR1H3 CAMK1G SIK3 HDAC1 VEGFA	1.71e-07	1263	84	20	int:HSP90AA1
Interaction	STIP1 interactions	MRE11 MLF2 DDX46 IPO8 COPG1 MTOR POLD1 CSNK2A1 POLR2A DHFR2 SIK3 RRM1 CSNK2A3 DNM2 HDAC1 LRRC9	3.43e-06	1006	84	16	int:STIP1
Interaction	EGLN3 interactions	MRE11 MLF2 ISYNA1 IPO8 COPG1 POLD1 CSNK2A1 GLI3 POLR2A SEC24B ARID5B SIK2 SIK3 RRM1 NDUFA9 ALG1 DNM2	2.07e-05	1296	84	17	int:EGLN3
Cytoband	10q21.2	RTKN2 ARID5B	1.21e-04	9	85	2	10q21.2
Cytoband	17q23.1	EPX TUBD1	4.00e-04	16	85	2	17q23.1
Cytoband	12p11.21	DENND5B IPO8	7.64e-04	22	85	2	12p11.21
Cytoband	11q25	ADAMTS15 ADAMTS8	1.07e-03	26	85	2	11q25
Cytoband	Ensembl 112 genes in cytogenetic band chr10q21	RTKN2 ADO ARID5B	1.40e-03	118	85	3	chr10q21
Cytoband	17p13.1	TNK1 POLR2A GUCY2D	1.40e-03	118	85	3	17p13.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR6A2 OR51M1 SLC6A5 RRM1 CSNK2A3	4.03e-03	564	85	5	chr11p15
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS15 ADAMTS8	1.61e-03	19	57	2	50
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF729 ZNF711 ZNF410 GLI1 GLI3 ZNF317 ZNF606 ZNF710	1.76e-03	718	57	8	28
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC14 ZDHHC3	2.58e-03	24	57	2	76
Coexpression	GSE5099_UNSTIM_VS_MCSF_TREATED_MONOCYTE_DAY7_DN	ZNF711 RTKN2 ADO RNF112 POLR2A TRRAP ZNF710	3.74e-06	200	84	7	M6585
Coexpression	JAIN_NFKB_SIGNALING	JAK2 MRE11 DDX46 IPO8 VEGFA	4.34e-06	75	84	5	M17646
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA POLD1 ARID5B ADAMTS15 ADAMTS8 VEGFA	1.10e-07	199	85	7	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	JAK2 PDGFRA POLD1 ARID5B ATP13A3 ADAMTS8 VEGFA	1.10e-07	199	85	7	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Pericytes-Donor_01\|World / lung cells shred on cell class, cell subclass, sample id	ISYNA1 GUCY1A2 PDGFRA RNF112 ADAMTS15 ADAMTS8	1.31e-06	181	85	6	ff445a8e56522e57e27405184d123cf905caf8cc
ToppCell	E18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	JAK2 ZNF410 GPR19 TENM4 PDGFRA AMIGO2	1.44e-06	184	85	6	a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA POLD1 ARID5B ADAMTS8 VEGFA	2.27e-06	199	85	6	ba586690f88fd051f449753bfe7603a2cb431782
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA POLD1 ARID5B ADAMTS8 VEGFA	2.27e-06	199	85	6	38ed3bc7daa993d9edcf3e7834597ebb06dd24f8
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA POLD1 ARID5B ADAMTS8 VEGFA	2.27e-06	199	85	6	06a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	JAK2 PDGFRA POLD1 ARID5B ADAMTS8 VEGFA	2.27e-06	199	85	6	fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA POLD1 ARID5B ADAMTS15 ADAMTS8	2.34e-06	200	85	6	ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TTBK1 MTOR DHFR RRM1 AMIGO2	1.44e-05	161	85	5	f4f5d6eaa32169de699c8ff8e8ae35179c8e25c0
ToppCell	356C-Fibroblasts-Fibroblast-D\|356C / Donor, Lineage, Cell class and subclass (all cells)	GUCY1A2 PDGFRA GLI1 GLI3 ADAMTS8	1.66e-05	166	85	5	7286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell	356C-Fibroblasts-Fibroblast-D-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GUCY1A2 PDGFRA GLI1 GLI3 ADAMTS8	1.66e-05	166	85	5	7c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERBB4 TENM4 ZDHHC14 ADAMTS15 SIAH3	2.14e-05	175	85	5	e5467dacf81f1f913b1719931cf1a7331434a7e7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RTKN2 GPR19 GLI3 ARID5B HDAC1	2.14e-05	175	85	5	16c835e62a3321f6cf6163954889946bbb869498
ToppCell	URO-Lymphocyte-T_NK-dnT\|URO / Disease, Lineage and Cell Type	GLI1 RNF112 AIG1 NR1H3 ZNF606	2.59e-05	182	85	5	f2b1c524301d0f2d1b69c46f3653fd53c21c3aa0
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXO40 NRAP MYLK4 CAMK1G EPX	2.87e-05	186	85	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBXO40 NRAP MYLK4 CAMK1G EPX	2.87e-05	186	85	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	ERAP2 ADAMTS15 NR1H3 ADA2 AMIGO2	3.10e-05	189	85	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	JAK2 ERBB4 NRAP ZDHHC14 SIK3	3.18e-05	190	85	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TGM2 TENM4 GUCY1A2 GLI3 ZDHHC14	3.51e-05	194	85	5	35f132cc38ac133be01834ed0946188aa0757eb4
ToppCell	distal-mesenchymal-Lipofibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDGFRA GLI3 ARID5B ADAMTS15 VEGFA	3.78e-05	197	85	5	865010edcd7e3f79f505fcef7b33882095994aa8
ToppCell	distal-mesenchymal-Lipofibroblast\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	PDGFRA GLI3 ARID5B ADAMTS15 VEGFA	3.78e-05	197	85	5	ceb83bdef16b58ee16193413bfb006f7715728b2
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA ADAMTS15 ADAMTS8 VEGFA	3.96e-05	199	85	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_only-Mesenchymal_fibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	PDGFRA POLD1 ARID5B ADAMTS8 VEGFA	3.96e-05	199	85	5	211c3a08f2d484ab7a3368006767289088f0d957
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts\|LPS_only / Treatment groups by lineage, cell group, cell type	PDGFRA POLD1 ARID5B ADAMTS8 VEGFA	3.96e-05	199	85	5	1a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	PDGFRA ARID5B ADAMTS15 ADAMTS8 VEGFA	4.06e-05	200	85	5	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Sepsis-URO-Lymphocyte-T/NK-dn_T\|URO / Disease, condition lineage and cell class	GLI1 RNF112 AIG1 NR1H3 ZNF606	4.06e-05	200	85	5	04ea6381b93a5d8bbeda4d71c788d7fbac6d40bc
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA ARID5B ADAMTS15 ADAMTS8	4.06e-05	200	85	5	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TGM2 PDGFRA ARID5B ADAMTS15 ADAMTS8	4.06e-05	200	85	5	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells-Stem_cells\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ISYNA1 AASS POLD1 GLI3 DHFR	4.06e-05	200	85	5	c00cc0b91baa37828895d9d6b8acbc6aa503215a
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Stem_cells\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	ISYNA1 AASS POLD1 GLI3 DHFR	4.06e-05	200	85	5	9e1b62a703fb7d413ce580448a1df5127c28e8a7
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	PDGFRA ARID5B ADAMTS15 ADAMTS8 VEGFA	4.06e-05	200	85	5	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AASS GLI1 GLI3 EPX	8.52e-05	121	85	4	8334a6b2ced1d6a4808458d6d4232d1b688ba28a
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AASS GLI1 GLI3 EPX	8.52e-05	121	85	4	4b33eeed7b70da120133b14d42c104d2461d52dc
ToppCell	Hippocampus-Macroglia-ASTROCYTE-Gja1-Astrocyte.Gja1.Nnat_(Nnat)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	AASS GLI1 GLI3 EPX	8.52e-05	121	85	4	a33e4ae0b0efb702db1b646ac0486e3b6ce48457
Drug	sunitinib	JAK2 ERBB4 PDGFRA MTOR CAMK1G ALG1 VEGFA	5.73e-07	130	85	7	CID005329102
Drug	quinazoline	ERBB4 PDGFRA DHFR DHFR2 VEGFA	6.91e-06	71	85	5	CID000009210
Drug	manganese	MRE11 ERBB4 ISYNA1 TTBK1 GUCY1A2 MTOR POLD1 CSNK2A1 POLR2A GUCY2D RRM1 EPX TUBD1	7.15e-06	791	85	13	CID000023930
Drug	PHA-00767505E [723337-45-9]; Up 200; 10uM; PC3; HT_HG-U133A	JAK2 PDGFRA GLI3 AIG1 HTATSF1 NR1H3 ZNF710	8.52e-06	195	85	7	6545_UP
Drug	NSC-107146	DHFR DHFR2	1.38e-05	2	85	2	CID000267616
Drug	gamma-tBAMT	DHFR DHFR2	1.38e-05	2	85	2	CID000125341
Drug	aditoprim	DHFR DHFR2	1.38e-05	2	85	2	CID000068755
Drug	2,4-diamino-5-benzylpyrimidine	DHFR DHFR2	1.38e-05	2	85	2	CID000081752
Drug	methotrexate-alpha-aspartate	DHFR DHFR2	1.38e-05	2	85	2	CID000100376
Drug	ethyl isocyanatoacetate	DHFR DHFR2	1.38e-05	2	85	2	CID000076283
Drug	3'-fluoroaminopterin	DHFR DHFR2	1.38e-05	2	85	2	CID000128780
Drug	DIVEMA-MTX	DHFR DHFR2	1.38e-05	2	85	2	CID000430857
Drug	4-ethylacetophenone	DHFR DHFR2	1.38e-05	2	85	2	CID000013642
Drug	2,4-diamino-5-phenylpyrimidine	DHFR DHFR2	1.38e-05	2	85	2	CID000134761
Drug	AC1L2J0W	POLD1 POLR2A DHFR RRM1	1.82e-05	42	85	4	CID000072957
Drug	AC1LA4KK	DHFR DHFR2 RRM1	3.29e-05	17	85	3	CID000481402
Drug	GTP - Na	TGM2 ADO GUCY1A2 COPG1 MTOR POLD1 CSNK2A1 POLR2A DHFR GUCY2D SEC24B TUBD1 DNM2	3.63e-05	923	85	13	CID000000762
Drug	chloromethyl pivalate	DHFR DHFR2	4.12e-05	3	85	2	CID000087885
Drug	beta-dimethylaminopropiophenone	DHFR2 RRM1	4.12e-05	3	85	2	CID000077042
Drug	F2Glu	DHFR DHFR2	4.12e-05	3	85	2	CID000125424
Drug	2,4,5,6-Tetraaminopyrimidine sulfate	DHFR DHFR2	4.12e-05	3	85	2	CID000070487
Drug	GNF-Pf-26	DHFR DHFR2	4.12e-05	3	85	2	CID000093114
Drug	diaveridine	DHFR DHFR2	4.12e-05	3	85	2	CID000021453
Drug	I--254	DHFR DHFR2	4.12e-05	3	85	2	CID000032285
Drug	8-deazahomofolic acid	DHFR DHFR2	4.12e-05	3	85	2	CID000130665
Drug	chloroformamidine hydrochloride	DHFR DHFR2	4.12e-05	3	85	2	CID003084509
Drug	DMDP derivative	DHFR DHFR2	4.12e-05	3	85	2	CID000482165
Drug	MTX-gamma-DMPE	DHFR DHFR2	4.12e-05	3	85	2	CID000146936
Drug	dihydropteroylhexaglutamate	DHFR DHFR2	4.12e-05	3	85	2	CID000193840
Drug	Dietary Sucrose	TENM4 NRAP PDGFRA GLI1 FNDC11 GLI3 ATCAY SLC6A5 ADAMTS15 CAMK1G PRSS46P LRRC9 VEGFA	4.48e-05	942	85	13	ctd:D019422
Drug	rosiglitazone maleate; Up 200; 10uM; PC3; HG-U133A	TGM2 NOL6 ATP13A3 C2CD2 AMIGO2 VEGFA	8.13e-05	191	85	6	430_UP
Drug	Rapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A	JAK2 TGM2 GLI3 ZDHHC14 SIK2 VEGFA	8.13e-05	191	85	6	5567_DN
Drug	5-deazaaminopterin	DHFR DHFR2	8.22e-05	4	85	2	CID000097272
Drug	AC1MQVYC	DHFR DHFR2	8.22e-05	4	85	2	CID003483303
Drug	methasquin	DHFR DHFR2	8.22e-05	4	85	2	CID000029335
Drug	2'-fluoro-2'-deoxycytidine	POLD1 RRM1	8.22e-05	4	85	2	CID000101507
Drug	ethyl 4-acetylbenzoate	DHFR DHFR2	8.22e-05	4	85	2	CID000600911
Drug	pY490	DHFR DHFR2	8.22e-05	4	85	2	CID000283017
Drug	K 130	DHFR DHFR2	8.22e-05	4	85	2	CID000467834
Drug	2,4-diamino-6-nitroquinazoline	DHFR DHFR2	8.22e-05	4	85	2	CID000252163
Drug	pergularinine	DHFR DHFR2	8.22e-05	4	85	2	CID000264751
Drug	5,8-dideazafolic acid	DHFR DHFR2	8.22e-05	4	85	2	CID003080619
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; PC3; HT_HG-U133A	JAK2 TNK1 ERAP2 NR1H3 PLCD1 ZNF606	8.86e-05	194	85	6	4263_DN
Drug	Nitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A	JAK2 TGM2 GUCY1A2 ATP13A3 PLCD1 VEGFA	9.11e-05	195	85	6	5405_UP
Drug	3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Up 200; 13.8uM; MCF7; HT_HG-U133A	DENND5B TGM2 TENM4 FNDC11 GUCY2D EPX	9.37e-05	196	85	6	6060_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; ssMCF7; HG-U133A	GPR19 CSNK2A1 HTATSF1 ATP13A3 EPX VEGFA	9.64e-05	197	85	6	415_UP
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A	ZNF711 DENND5B TGM2 ZDHHC14 EPX VEGFA	9.64e-05	197	85	6	5643_DN
Drug	Procainamide hydrochloride [614-39-1]; Down 200; 14.8uM; MCF7; HT_HG-U133A	AIG1 NR1H3 SPAG8 ZNF606 ZNF710 VEGFA	9.64e-05	197	85	6	5663_DN
Drug	Graveoline [485-61-0]; Up 200; 14.4uM; HL60; HT_HG-U133A	TNK1 PDGFRA GLI1 GLI3 NOL6 AIG1	1.02e-04	199	85	6	2179_UP
Drug	tylophorinidine	DHFR DHFR2	1.37e-04	5	85	2	CID000161749
Drug	piritrexim isethionate	DHFR DHFR2	1.37e-04	5	85	2	CID000054368
Drug	chlorasquin	DHFR DHFR2	1.37e-04	5	85	2	CID000029336
Drug	2-desamino-2-methylaminopterin	DHFR DHFR2	1.37e-04	5	85	2	CID000164085
Drug	NVP ADW742	MTOR VEGFA	1.37e-04	5	85	2	ctd:C502355
Drug	deoxytubulosine	DHFR DHFR2	1.37e-04	5	85	2	CID000165003
Drug	3-(4-bromophenyl)-2-(ethylsulfonyl)-6-methylquinoxaline-1,4-dioxide	MTOR VEGFA	1.37e-04	5	85	2	ctd:C528740
Drug	bruceine	DHFR RRM1	1.37e-04	5	85	2	CID000122785
Drug	methylbenzoprim	DHFR DHFR2	1.37e-04	5	85	2	CID000072438
Drug	pemetrexed	DHFR RRM1 EPX VEGFA	1.53e-04	72	85	4	CID000060843
Drug	perfosfamide	MRE11 POLD1 SDF4 VEGFA	1.71e-04	74	85	4	ctd:C011272
Drug	11-deazahomofolic acid	DHFR DHFR2	2.05e-04	6	85	2	CID000128960
Drug	10-methyl-11-deazahomofolic acid	DHFR DHFR2	2.05e-04	6	85	2	CID000128963
Drug	II 19	DHFR EPX	2.05e-04	6	85	2	CID000040321
Drug	NBMPR-P	DHFR DHFR2	2.05e-04	6	85	2	CID006335125
Drug	4-thio-5-fluoro-dUMP	DHFR DHFR2	2.05e-04	6	85	2	CID003035986
Drug	N(G)-nitro-L-arginine methyl ester	ISYNA1 ADO GUCY1A2 GLI3 VEGFA	2.20e-04	146	85	5	CID000003864
Disease	migraine without aura, susceptibility to, 4, age at onset	NRAP NOL6	7.44e-06	2	81	2	EFO_0004847, MONDO_0011847
Disease	Metastatic melanoma	TTBK1 PDGFRA MTOR GUCY2D	1.50e-05	54	81	4	C0278883
Disease	ovarian hyperstimulation syndrome (implicated_via_orthology)	NR1H3 VEGFA	2.23e-05	3	81	2	DOID:5425 (implicated_via_orthology)
Disease	migraine disorder, age at onset	NRAP NOL6	2.23e-05	3	81	2	EFO_0004847, MONDO_0005277
Disease	liver cancer (implicated_via_orthology)	JAK2 MRE11	4.45e-05	4	81	2	DOID:3571 (implicated_via_orthology)
Disease	Glioblastoma	TGM2 PDGFRA MTOR VEGFA	6.77e-05	79	81	4	C0017636
Disease	Large cell carcinoma of lung	TTBK1 MTOR TRRAP	9.33e-05	32	81	3	C0345958
Disease	cervical cancer	JAK2 MTOR VEGFA	1.12e-04	34	81	3	C4048328
Disease	Uterine Cervical Neoplasm	JAK2 MTOR VEGFA	1.22e-04	35	81	3	C0007873
Disease	glypican-1 measurement	NRAP NOL6	1.55e-04	7	81	2	EFO_0801649
Disease	colon cancer (biomarker_via_orthology)	JAK2 MTOR VEGFA	1.70e-04	39	81	3	DOID:219 (biomarker_via_orthology)
Disease	Combined immunodeficiency	TTC7A DCLRE1C ADA2	1.97e-04	41	81	3	C0494261
Disease	Cutaneous Melanoma	ERBB4 PDGFRA TRRAP	1.97e-04	41	81	3	C0151779
Disease	Anorectal Malformations	TTC7A JAK2 GLI3	1.97e-04	41	81	3	C3495676
Disease	Glioblastoma Multiforme	TGM2 PDGFRA MTOR VEGFA	2.52e-04	111	81	4	C1621958
Disease	middle cerebral artery infarction (implicated_via_orthology)	PDGFRA MTOR VEGFA	2.60e-04	45	81	3	DOID:3525 (implicated_via_orthology)
Disease	primary bacterial infectious disease (implicated_via_orthology)	GLI1 GLI3	2.65e-04	9	81	2	DOID:0050338 (implicated_via_orthology)
Disease	Gastrointestinal Stromal Sarcoma	PDGFRA GLI1 GLI3	2.96e-04	47	81	3	C3179349
Disease	Gastrointestinal Stromal Tumors	PDGFRA GLI1 GLI3	3.56e-04	50	81	3	C0238198
Disease	renal cell carcinoma (is_marker_for)	ERBB4 PDGFRA MTOR VEGFA	4.34e-04	128	81	4	DOID:4450 (is_marker_for)
Disease	progression free survival, urinary bladder cancer	ERBB4 TENM4	4.83e-04	12	81	2	EFO_0004920, MONDO_0001187
Disease	triglycerides to total lipids in medium HDL percentage	NR1H3 SIK3 VEGFA	4.97e-04	56	81	3	EFO_0022333
Disease	ventricular enlargement measurement	SRCIN1 SIAH3	5.69e-04	13	81	2	EFO_0010570
Disease	leukemia (is_implicated_in)	JAK2 PDGFRA	5.69e-04	13	81	2	DOID:1240 (is_implicated_in)
Disease	Colorectal Carcinoma	TGM2 MLF2 GUCY1A2 POLD1 GLI3 DHFR ADAMTS15 SDF4	6.89e-04	702	81	8	C0009402
Disease	Schizophrenia	TGM2 RTKN2 ERBB4 TENM4 MTOR SLC6A5 SDF4 TRRAP HDAC1	7.03e-04	883	81	9	C0036341
Disease	1,3,7-trimethylurate measurement	RTKN2 ARID5B	7.64e-04	15	81	2	EFO_0021172
Disease	breast carcinoma (is_marker_for)	MRE11 PDGFRA HDAC1	8.05e-04	66	81	3	DOID:3459 (is_marker_for)
Disease	myocardial infarction (implicated_via_orthology)	JAK2 MTOR VEGFA	8.05e-04	66	81	3	DOID:5844 (implicated_via_orthology)
Disease	response to haloperidol	RTKN2 ARID5B	8.71e-04	16	81	2	GO_1905119
Disease	pre-malignant neoplasm (biomarker_via_orthology)	GLI1 GLI3	9.85e-04	17	81	2	DOID:0060071 (biomarker_via_orthology)
Disease	Familial primary pulmonary hypertension	ATP13A3 HDAC1	9.85e-04	17	81	2	C0340543
Disease	portal hypertension (implicated_via_orthology)	JAK2 MTOR	1.23e-03	19	81	2	DOID:10762 (implicated_via_orthology)
Disease	liver cirrhosis (is_marker_for)	JAK2 GLI3 VEGFA	1.51e-03	82	81	3	DOID:5082 (is_marker_for)
Disease	Infiltrating duct carcinoma of female breast	MYLK4 CAMK1G	1.51e-03	21	81	2	C3165106
Disease	Giant Cell Glioblastoma	TGM2 MTOR VEGFA	1.62e-03	84	81	3	C0334588
Disease	seminoma (is_marker_for)	PDGFRA VEGFA	1.66e-03	22	81	2	DOID:4440 (is_marker_for)
Disease	fat intake measurement	NRAP NOL6	1.66e-03	22	81	2	EFO_0010809
Disease	Ovarian Serous Adenocarcinoma	JAK2 TRRAP	1.81e-03	23	81	2	C1335177
Disease	triacylglycerol 56:4 measurement	IPO8 SIK3	1.98e-03	24	81	2	EFO_0010431
Disease	diastolic blood pressure, systolic blood pressure	RTKN2 TENM4 GUCY2D ARID5B AIG1 ADAMTS15 ADAMTS8	2.46e-03	670	81	7	EFO_0006335, EFO_0006336
Disease	glaucoma (biomarker_via_orthology)	HDAC1 VEGFA	2.69e-03	28	81	2	DOID:1686 (biomarker_via_orthology)
Disease	Iniencephaly	GLI3 RRM1	2.69e-03	28	81	2	C0152234
Disease	Acrania	GLI3 RRM1	2.69e-03	28	81	2	C0702169
Disease	Tethered Cord Syndrome	GLI3 RRM1	2.69e-03	28	81	2	C0080218
Disease	Spinal Cord Myelodysplasia	GLI3 RRM1	2.69e-03	28	81	2	C0344479
Disease	Exencephaly	GLI3 RRM1	2.69e-03	28	81	2	C0266453
Disease	Neurenteric Cyst	GLI3 RRM1	2.69e-03	28	81	2	C0027806
Disease	Diastematomyelia	GLI3 RRM1	2.69e-03	28	81	2	C0011999
Disease	Malignant neoplasm of breast	MRE11 TGM2 ERBB4 GUCY1A2 MTOR GLI1 DHFR SLC6A5 SIK3	2.71e-03	1074	81	9	C0006142

Protein segments in the cluster

Peptide	Gene	Start	Entry
IMASMDHPHLVRLLG	ERBB4	771	Q15303
HGMHTTVLPFILIEM	AIG1	131	Q9NVV5
PLDLQHRLFMKLGSM	ALG1	226	Q9BT22
HRLFMKLGSMHSPFR	ALG1	231	Q9BT22
HPEHSRGMLRFMVKE	SDF4	226	Q9BRK5
LHDHPGMHGMLKVLY	ADO	111	Q96SZ5
VPKLMLHGTVFARMA	ATP13A3	846	Q9H7F0
MGKHHVMAPLFVHLN	ADAMTS8	386	Q9UP79
MVFAHRMDNSKPHLI	GPR19	1	Q15760
MGLRLLALGHHTPFM	AASS	166	Q9UDR5
SMPMHHINLVPGKQL	AMIGO2	206	Q86SJ2
FGKLRANHMMSPTLI	ADAMTS15	381	Q8TE58
LQRPTHMNQMVFHKI	JAK2	526	O60674
HMLLEHKMERPGPSL	ISYNA1	501	Q9NPH2
VYGNPICRKMLHRHM	LRRC9	1326	Q6ZRR7
HHPHDRLMFPRMLMK	NR1H3	396	Q13133
LMSELKIMTHLGPHL	PDGFRA	641	P16234
YMLVVHMRRHTGEKP	GLI3	531	P10071
QFHLPMDMVHLVHAK	NRAP	1356	Q86VF7
YVRHRLLHMQMVSGP	GUCY2D	486	Q02846
QGHPMKPHRIRMTHN	HDAC1	26	Q13547
IDLHMIRPYMKVVTH	ATCAY	166	Q86WG3
FILMGLFRQSKHPMA	OR2T4	16	Q8NH00
PMMGLSLVHRFGKHA	OR51M1	266	Q9H341
TPKLAAMHTLFMREH	EPX	381	P11678
MTPKPMIRAFDHVLH	NOL6	461	Q9H6R4
FSNLHIIHPTMKMLL	DNAH12	201	Q6ZR08
RHMHQMYILHLDLKP	MYLK4	216	Q86YV6
YMLVVHMRRHTGEKP	GLI1	286	P08151
IPLTARMVMAHLVNH	RALGAPA2	1371	Q2PPJ7
RHMADRMGTPHLQKT	DNM2	266	P50570
RMHITDMKLPHLPGL	NDUFA9	321	Q16795
HMRKLHMNLHSPGVR	CAMK1G	316	Q96NX5
MARHLHAILGPMLLN	PLCD1	401	P51178
RHERVVIIKNMFHPM	HTATSF1	261	O43719
GIMHRDVKPHNVMID	CSNK2A3	151	Q8NEV1
MRLSPFHLQLEFHMK	C2CD2	156	Q9Y426
KLDMFRNMPEILHHL	DCLRE1C	231	Q96SD1
MMVPGRLHVKHRLVS	FNDC11	176	Q9BVV2
MNHPGHLKLFVTRIM	DHFR	126	P00374
QRLMKMDHTAIHPHL	DENND5B	626	Q6ZUT9
ILRMMPKGAALHLHD	ADA2	101	Q9NZK5
GIMHRDVKPHNVMID	CSNK2A1	151	P68400
LVHNGRMLIHFGQMP	FBXO40	311	Q9UH90
AMVNSHRKPMFNIHR	ERAP2	6	Q6P179
MNHLGHLKLFVTRIM	DHFR2	126	Q86XF0
PRKHAVLMNFLFTML	COPG1	391	Q9Y678
GKTIAFLLPMFRHIM	DDX46	421	Q7L014
PLTRMVIHKDFSNLM	PRSS46P	111	E5RG02
VHLMKMIHPNLYRID	SEC24B	1111	O95487
RQAMHEGLLMPVVKS	POLD1	561	P28340
LMDPFAIHRQHMSRM	MLF2	16	Q15773
IIMAIRNHSTLHKPM	OR6A2	46	O95222
MKPHVRPIMQELLHI	IPO8	536	O15397
LPQLIPHMLRVFMHD	MTOR	1071	P42345
HPHHIVGFAMLGMIK	GUCY1A2	241	P33402
STLMHHLQKPMAAPR	RTKN2	546	Q8IZC4
HGHRGLLTMQLKSPM	SPAG8	311	Q99932
IMFVIKMHLAPGRFI	SLC6A5	731	Q9Y345
REVQIMKMLDHPHII	SIK2	66	Q9H0K1
FREVQIMKMLCHPHI	SIK3	111	Q9Y2K2
IMKMLCHPHIIRLYQ	SIK3	116	Q9Y2K2
RHEGHPQFFATMMLI	SIAH3	176	Q8IW03
GRKMNMHKIPLHTVR	MRE11	291	P49959
MHKIPLHTVRQFFME	MRE11	296	P49959
FRKMEGMVHPILHRK	ARID5B	986	Q14865
GMVHPILHRKMSPQN	ARID5B	991	Q14865
RMDLLPLHMGLHKLV	TGM2	651	P21980
MKPHGRLQKVMNHIT	RNF213	501	Q63HN8
HPEFKMLSVRNIPHM	TUBD1	266	Q9UJT1
EHRMLLKHMPSEFHL	TTBK1	256	Q5TCY1
MMLIPTHHFRNIERK	ZDHHC3	1	Q9NYG2
MGKHYGMVPIQHLDL	RNF112	301	Q9ULX5
LHALIAHMFPQKLTM	SRCIN1	206	Q9C0H9
RPQHMLMRVSVGIHK	RRM1	166	P23921
QPTLHKMSMMGHRVR	POLR2A	461	P24928
LKVHMRTHNGEKPFM	ZNF410	266	Q86VK4
MKRHMLIHTSVRPYQ	ZNF710	506	Q8N1W2
HPTIPFNLMKVHLMV	TENM4	1081	Q6N022
VMPRKDEHMGHQFLT	ZDHHC14	426	Q8IZN3
VMMNLEHPHVLRLHG	TNK1	171	Q13470
IMHSLGLMLSRLGHK	TTC7A	781	Q9ULT0
IMRIKPHQGQHIGEM	VEGFA	106	P15692
GFLKRHMKNHPDHLM	ZNF711	396	Q9Y462
KRLGMITHLFAMPLA	WDR87	946	Q6ZQQ6
DQIHTHMRPLLMMLG	TRRAP	1421	Q9Y4A5
VAFKGRPHLTQHMSM	ZNF317	201	Q96PQ6
HLIAHMRMHTGEKPF	ZNF606	526	Q8WXB4
RHEMVTKPPVMRSHF	ZNF729	76	A6NN14