Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	ZC3H8 HSF1 HSF2	7.19e-05	13	129	3	GO:0001162
GeneOntologyMolecularFunction	actin filament binding	IQGAP2 SPTA1 SPTBN1 PSTPIP1 SPTBN4 XIRP2 MACF1 ARPC5L	1.16e-04	227	129	8	GO:0051015
GeneOntologyMolecularFunction	intronic transcription regulatory region sequence-specific DNA binding	ZC3H8 HSF1 HSF2	1.68e-04	17	129	3	GO:0001161
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR2	2.46e-04	4	129	2	GO:0005219
GeneOntologyMolecularFunction	actin binding	IQGAP2 SPTA1 SPTBN1 PSTPIP1 SPTBN4 DST XIRP2 MACF1 ARPC5L PLEKHH2 UTRN	2.82e-04	479	129	11	GO:0003779
GeneOntologyMolecularFunction	ankyrin binding	SPTBN1 SPTBN4 PTPRC	4.24e-04	23	129	3	GO:0030506
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR2	6.11e-04	6	129	2	GO:0048763
GeneOntologyMolecularFunction	ankyrin repeat binding	SHANK1 TERF1	8.51e-04	7	129	2	GO:0071532
GeneOntologyCellularComponent	cell cortex	IQGAP2 SPTA1 SPTBN1 PSTPIP1 ITGB4 RYR1 SPTBN4 EXOC5 DST MACF1 PLEKHH2 PHLDB2	3.90e-06	371	131	12	GO:0005938
GeneOntologyCellularComponent	spectrin	SPTA1 SPTBN1 SPTBN4	1.97e-05	9	131	3	GO:0008091
GeneOntologyCellularComponent	cytoplasmic side of plasma membrane	SPTA1 NCF1 RYR1 RYR2 AP2M1 DST PTPRC	1.68e-04	185	131	7	GO:0009898
GeneOntologyCellularComponent	actin cytoskeleton	HDAC4 IQGAP2 SPTA1 SPTBN1 PSTPIP1 SPTBN4 KIF9 DST XIRP2 MACF1 ARPC5L PLEKHH2	2.76e-04	576	131	12	GO:0015629
GeneOntologyCellularComponent	cortical actin cytoskeleton	SPTA1 SPTBN1 PSTPIP1 SPTBN4 PLEKHH2	2.99e-04	93	131	5	GO:0030864
GeneOntologyCellularComponent	A band	HDAC4 SPTBN1 RYR2 DST	3.16e-04	52	131	4	GO:0031672
GeneOntologyCellularComponent	nuclear body	NUGGC SUMO4 RAD18 HDAC5 HDAC4 ZC3H8 MAML1 TERF1 SPTBN4 SRRT OTP ASCC3 PLEKHH2 HEATR5B HSF1	5.41e-04	903	131	15	GO:0016604
GeneOntologyCellularComponent	cytoplasmic side of membrane	SPTA1 NCF1 RYR1 RYR2 AP2M1 DST PTPRC	6.27e-04	230	131	7	GO:0098562
GeneOntologyCellularComponent	cell leading edge	IQGAP2 SPTBN1 PSTPIP1 ITGB4 IGF2BP1 DST MACF1 PLEKHH2 ACAP2 PHLDB2	1.22e-03	500	131	10	GO:0031252
GeneOntologyCellularComponent	cortical cytoskeleton	SPTA1 SPTBN1 PSTPIP1 SPTBN4 PLEKHH2	1.32e-03	129	131	5	GO:0030863
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	SPTA1 SPTBN1	1.36e-03	9	131	2	GO:0014731
HumanPheno	Broad philtrum	SPTBN1 CHD2 ZNF462 AP2M1 KMT2D ARID2	2.12e-06	45	45	6	HP:0000289
HumanPheno	Abnormal morphology of the nasal alae	ESS2 HDAC4 SPTBN1 KIAA0586 CHD2 RYR1 ZNF462 NEK1 AP2M1 KMT2D ARID2 VPS35L SUPT16H MED25 CKAP2L FOXP1 LTBP1 ASCC3	2.98e-06	639	45	18	HP:0000429
HumanPheno	Anteverted nares	HDAC4 SPTBN1 KIAA0586 CHD2 RYR1 ZNF462 NEK1 AP2M1 KMT2D ARID2 VPS35L SUPT16H MED25 FOXP1 LTBP1 ASCC3	1.10e-05	559	45	16	HP:0000463
HumanPheno	Upturned nose	HDAC4 SPTBN1 KIAA0586 CHD2 RYR1 ZNF462 NEK1 AP2M1 KMT2D ARID2 VPS35L SUPT16H MED25 FOXP1 LTBP1 ASCC3	1.10e-05	559	45	16	HP:0000427
HumanPheno	Abnormal nostril morphology	HDAC4 SPTBN1 KIAA0586 CHD2 RYR1 ZNF462 NEK1 AP2M1 KMT2D ARID2 VPS35L SUPT16H MED25 FOXP1 LTBP1 ASCC3	1.58e-05	575	45	16	HP:0005288
HumanPheno	Abnormal nasal tip morphology	ESS2 HDAC4 SPTBN1 RYR1 ZNF462 NEK1 KMT2D ARID2 SUPT16H MED25 FOXP1 LTBP1 WDR62	1.73e-05	386	45	13	HP:0000436
HumanPheno	Abnormal external nose morphology	ESS2 HDAC4 SPTBN1 KIAA0586 CHD2 RYR1 ZNF462 NEK1 AP2M1 KMT2D ARID2 VPS35L SUPT16H MED25 PKHD1 CKAP2L FOXP1 LTBP1 ASCC3 WDR62	3.41e-05	916	45	20	HP:0010938
HumanPheno	Ventricular septal defect	INTU ESS2 SPTBN1 NCF1 RYR1 ZNF462 NEK1 KMT2D DST ARID2 VPS35L MED25 CKAP2L MACF1	7.57e-05	510	45	14	HP:0001629
HumanPheno	Abnormal ventricular septum morphology	INTU ESS2 SPTBN1 NCF1 RYR1 ZNF462 NEK1 KMT2D DST ARID2 VPS35L MED25 CKAP2L MACF1	9.57e-05	521	45	14	HP:0010438
HumanPheno	Thick vermilion border	HDAC4 SPTBN1 NCF1 CHD2 AP2M1 KMT2D ARID2 SUPT16H FOXP1 LTBP1	1.19e-04	279	45	10	HP:0012471
HumanPheno	Thick lower lip vermilion	HDAC4 NCF1 CHD2 AP2M1 KMT2D ARID2 LTBP1	1.61e-04	136	45	7	HP:0000179
Domain	Spectrin	SPTA1 SPTBN1 SPTBN4 DST MACF1 UTRN	8.85e-09	23	129	6	PF00435
Domain	Spectrin_repeat	SPTA1 SPTBN1 SPTBN4 DST MACF1 UTRN	4.03e-08	29	129	6	IPR002017
Domain	SPEC	SPTA1 SPTBN1 SPTBN4 DST MACF1 UTRN	7.55e-08	32	129	6	SM00150
Domain	Spectrin/alpha-actinin	SPTA1 SPTBN1 SPTBN4 DST MACF1 UTRN	7.55e-08	32	129	6	IPR018159
Domain	ACTININ_2	SPTBN1 SPTBN4 DST MACF1 UTRN	4.43e-07	23	129	5	PS00020
Domain	ACTININ_1	SPTBN1 SPTBN4 DST MACF1 UTRN	4.43e-07	23	129	5	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 SPTBN4 DST MACF1 UTRN	4.43e-07	23	129	5	IPR001589
Domain	CH	IQGAP2 SPTBN1 SPTBN4 DST MACF1 UTRN	5.71e-06	65	129	6	SM00033
Domain	CH	IQGAP2 SPTBN1 SPTBN4 DST MACF1 UTRN	8.82e-06	70	129	6	PF00307
Domain	-	IQGAP2 SPTBN1 SPTBN4 DST MACF1 UTRN	9.58e-06	71	129	6	1.10.418.10
Domain	CH	IQGAP2 SPTBN1 SPTBN4 DST MACF1 UTRN	1.13e-05	73	129	6	PS50021
Domain	CH-domain	IQGAP2 SPTBN1 SPTBN4 DST MACF1 UTRN	1.32e-05	75	129	6	IPR001715
Domain	ER_stress-assoc	SERP2 SERP1	4.73e-05	2	129	2	IPR010580
Domain	Vert_HSTF_C	HSF1 HSF2	4.73e-05	2	129	2	IPR010542
Domain	Semenogelin	SEMG1 SEMG2	4.73e-05	2	129	2	PF05474
Domain	Vert_HS_TF	HSF1 HSF2	4.73e-05	2	129	2	PF06546
Domain	RAMP4	SERP2 SERP1	4.73e-05	2	129	2	PF06624
Domain	Semenogelin	SEMG1 SEMG2	4.73e-05	2	129	2	IPR008836
Domain	HDAC4_Gln	HDAC5 HDAC4	1.41e-04	3	129	2	PF12203
Domain	Ryanodine_rcpt	RYR1 RYR2	1.41e-04	3	129	2	IPR003032
Domain	Hist_deacetylase_Gln_rich_N	HDAC5 HDAC4	1.41e-04	3	129	2	IPR024643
Domain	Ryanrecept_TM4-6	RYR1 RYR2	1.41e-04	3	129	2	IPR009460
Domain	RyR	RYR1 RYR2	1.41e-04	3	129	2	PF02026
Domain	RR_TM4-6	RYR1 RYR2	1.41e-04	3	129	2	PF06459
Domain	Ryan_recept	RYR1 RYR2	1.41e-04	3	129	2	IPR013333
Domain	Spectrin_bsu	SPTBN1 SPTBN4	2.81e-04	4	129	2	IPR016343
Domain	Histone_deAcase_II_euk	HDAC5 HDAC4	2.81e-04	4	129	2	IPR017320
Domain	-	SPTA1 RYR1 RYR2 CAPN11 GUCA1C DST MACF1 UTRN	4.65e-04	261	129	8	1.10.238.10
Domain	Rad60-SLD	SUMO4 NFATC2IP	4.67e-04	5	129	2	PF11976
Domain	Rad60/SUMO-like_dom	SUMO4 NFATC2IP	4.67e-04	5	129	2	IPR022617
Domain	RIH_assoc-dom	RYR1 RYR2	6.97e-04	6	129	2	IPR013662
Domain	-	DST MACF1	6.97e-04	6	129	2	3.90.1290.10
Domain	GAR	DST MACF1	6.97e-04	6	129	2	PS51460
Domain	Ins145_P3_rec	RYR1 RYR2	6.97e-04	6	129	2	PF08709
Domain	GAS2	DST MACF1	6.97e-04	6	129	2	PF02187
Domain	HSF_fam	HSF1 HSF2	6.97e-04	6	129	2	IPR027725
Domain	RIH_assoc	RYR1 RYR2	6.97e-04	6	129	2	PF08454
Domain	RIH_dom	RYR1 RYR2	6.97e-04	6	129	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	6.97e-04	6	129	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	6.97e-04	6	129	2	IPR015925
Domain	-	RYR1 RYR2	6.97e-04	6	129	2	1.25.10.30
Domain	-	DST MACF1	6.97e-04	6	129	2	3.30.920.20
Domain	RYDR_ITPR	RYR1 RYR2	6.97e-04	6	129	2	PF01365
Domain	GAS_dom	DST MACF1	6.97e-04	6	129	2	IPR003108
Domain	GAS2	DST MACF1	6.97e-04	6	129	2	SM00243
Domain	PH	PHLDA1 SPTBN1 SPTBN4 ARHGEF39 OSBPL10 PLEKHH2 ACAP2 PHLDB2	7.03e-04	278	129	8	SM00233
Domain	PH_DOMAIN	PHLDA1 SPTBN1 SPTBN4 ARHGEF39 OSBPL10 PLEKHH2 ACAP2 PHLDB2	7.20e-04	279	129	8	PS50003
Domain	PH_domain	PHLDA1 SPTBN1 SPTBN4 ARHGEF39 OSBPL10 PLEKHH2 ACAP2 PHLDB2	7.36e-04	280	129	8	IPR001849
Domain	SH3	SHANK1 MACC1 SPTA1 NCF1 PSTPIP1 DST MACF1	7.62e-04	216	129	7	PS50002
Domain	EFh	SPTA1 RYR2 CAPN11 GUCA1C DST MACF1	8.06e-04	158	129	6	SM00054
Domain	SH3_domain	SHANK1 MACC1 SPTA1 NCF1 PSTPIP1 DST MACF1	8.49e-04	220	129	7	IPR001452
Domain	EF-hand-dom_pair	SPTA1 RYR1 RYR2 CAPN11 GUCA1C DST MACF1 UTRN	8.64e-04	287	129	8	IPR011992
Domain	HSF_DNA-bind	HSF1 HSF2	9.72e-04	7	129	2	PF00447
Domain	Plectin	DST MACF1	9.72e-04	7	129	2	PF00681
Domain	Plectin_repeat	DST MACF1	9.72e-04	7	129	2	IPR001101
Domain	HSF_DOMAIN	HSF1 HSF2	9.72e-04	7	129	2	PS00434
Domain	-	EFL1 SUPT16H	9.72e-04	7	129	2	3.30.70.240
Domain	HSF_DNA-bd	HSF1 HSF2	9.72e-04	7	129	2	IPR000232
Domain	HSF	HSF1 HSF2	9.72e-04	7	129	2	SM00415
Domain	EFG_V	EFL1 SUPT16H	9.72e-04	7	129	2	IPR000640
Domain	PLEC	DST MACF1	9.72e-04	7	129	2	SM00250
Domain	FYVE	FYCO1 MTMR3 EEA1	1.03e-03	29	129	3	PF01363
Domain	FYVE	FYCO1 MTMR3 EEA1	1.03e-03	29	129	3	SM00064
Domain	EF_hand_dom	SPTA1 RYR1 RYR2 CAPN11 GUCA1C DST MACF1	1.16e-03	232	129	7	IPR002048
Domain	-	PHLDA1 SPTBN1 SPTBN4 ARHGEF39 MTMR3 OSBPL10 PLEKHH2 ACAP2 PHLDB2	1.59e-03	391	129	9	2.30.29.30
Domain	Znf_FYVE-rel	FYCO1 MTMR3 EEA1	1.65e-03	34	129	3	IPR017455
Domain	EF-hand_8	RYR1 RYR2 CAPN11	1.65e-03	34	129	3	PF13833
Domain	PH_dom-spectrin-type	SPTBN1 SPTBN4	1.65e-03	9	129	2	IPR001605
Domain	MIR	RYR1 RYR2	2.05e-03	10	129	2	PF02815
Domain	MIR_motif	RYR1 RYR2	2.05e-03	10	129	2	IPR016093
Domain	MIR	RYR1 RYR2	2.05e-03	10	129	2	PS50919
Domain	MIR	RYR1 RYR2	2.05e-03	10	129	2	SM00472
Domain	Znf_FYVE	FYCO1 MTMR3 EEA1	2.28e-03	38	129	3	IPR000306
Domain	Hist_deacetyl	HDAC5 HDAC4	2.50e-03	11	129	2	PF00850
Domain	-	HDAC5 HDAC4	2.50e-03	11	129	2	3.40.800.20
Domain	His_deacetylse_dom	HDAC5 HDAC4	2.50e-03	11	129	2	IPR023801
Domain	His_deacetylse	HDAC5 HDAC4	2.50e-03	11	129	2	IPR000286
Domain	ZF_FYVE	FYCO1 MTMR3 EEA1	2.64e-03	40	129	3	PS50178
Domain	PH_dom-like	PHLDA1 SPTBN1 SPTBN4 ARHGEF39 MTMR3 OSBPL10 PLEKHH2 ACAP2 PHLDB2	2.83e-03	426	129	9	IPR011993
Domain	EF-hand_1	RYR2 CAPN11 GUCA1C DST MACF1	4.10e-03	152	129	5	PF00036
Domain	Spectrin_alpha_SH3	SPTA1 PSTPIP1	4.69e-03	15	129	2	IPR013315
Domain	PH	SPTBN1 SPTBN4 OSBPL10 PLEKHH2 ACAP2 PHLDB2	5.18e-03	229	129	6	PF00169
Domain	EF_HAND_2	SPTA1 RYR2 CAPN11 GUCA1C DST MACF1	5.40e-03	231	129	6	PS50222
Domain	Ig_E-set	TGM1 KCNJ10 PKHD1 ASCC3	5.87e-03	104	129	4	IPR014756
Domain	Helicase_C	CHD2 HLTF ASCC3 DHX29	6.48e-03	107	129	4	PF00271
Domain	HELICc	CHD2 HLTF ASCC3 DHX29	6.48e-03	107	129	4	SM00490
Domain	Helicase_C	CHD2 HLTF ASCC3 DHX29	6.70e-03	108	129	4	IPR001650
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTA1 SPTBN1 SPTBN4	3.89e-05	10	99	3	MM15112
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 HDAC5 RPAP3 ZNF462 NEK1 KMT2D DST RESF1 GCC2 FOXP1 ASCC3 GCN1 UTRN GOLGB1 WDR62	7.37e-11	418	132	15	34709266
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	TANC2 INTU DENND4A HDAC5 HDAC4 IQGAP2 RPAP3 MAML1 SPAG9 NEK1 EXOC5 AP2M1 KIF3B GCC2 SUPT16H SNAPC1 EEA1 HSF1 ACAP2 GCN1 COA7 PHLDB2 WDR62	1.01e-09	1321	132	23	27173435
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MACC1 INTU DENND4A IQGAP2 SPTA1 SPTBN1 RRP15 CHD2 SERP2 ODF2 SERP1 TTC3 RYR2 CAPN11 SPTBN4 AP2M1 DST SUPT16H PKHD1 MACF1 ARPC5L EEA1 CCDC89 GOLGB1	1.02e-09	1442	132	24	35575683
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 TRERF1 TANC2 HDAC4 IQGAP2 SPTBN1 FYCO1 TTC3 ZNF462 SPTBN4 KIF3B DST FAM120A KCNJ10 SUPT16H MACF1 WNK2 GOLGB1 PHLDB2	4.61e-09	963	132	19	28671696
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TANC2 KIAA0586 SPAG9 ZNF623 SEMA4G ZNF462 PWWP2A NEK1 AP2M1 FAM120A ARID2 MACF1 DDHD2 PLEKHH2	6.56e-09	493	132	14	15368895
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RAD18 MCMBP ESS2 HDAC5 NCF1 MAML1 COPS7A RESF1 NFATC2IP ARID2 MED25 MACF1 HSF2 GOLGB1 ZNF574	7.72e-09	588	132	15	38580884
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	DENND4A KIAA0586 NEK1 DST FAM120A MACF1 DDHD2 ASCC3 UTRN WDR62	8.17e-09	209	132	10	36779422
Pubmed	Human transcription factor protein interaction networks.	TRERF1 RAD18 ESS2 HDAC5 SPTBN1 MAML1 RRP15 SPAG9 YTHDF1 ZNF462 SRRT IGF2BP1 AP2M1 KMT2D DST RESF1 FAM120A NKX2-4 ARID2 GMEB1 FOXP1 FILIP1L	2.24e-08	1429	132	22	35140242
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	IQGAP2 RRP15 TERF1 SRRT EXOC5 IGF2BP1 AP2M1 FAM120A ARID2 SUPT16H CKAP2L MACF1 ASCC3 HSF2 GCN1 DHX29	3.40e-08	759	132	16	35915203
Pubmed	Semenogelin I and semenogelin II, the major gel-forming proteins in human semen, are substrates for transglutaminase.	SEMG1 SEMG2 TGM1	5.34e-08	3	132	3	9523691
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RAD18 MCMBP ITGB4 SRRT IGF2BP1 FAM120A NFATC2IP GCC2 GMEB1 DHX29 PHLDB2 MOCOS ZNF574	7.00e-08	503	132	13	16964243
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	TANC2 DENND4A MCMBP HDAC4 SPTBN1 TMCC3 SRRT NEK1 DST RESF1 OSBPL10 MACF1 UTRN GOLGB1 PHLDB2 WDR62	1.88e-07	861	132	16	36931259
Pubmed	Functional proteomics mapping of a human signaling pathway.	SPTBN1 TTC3 TERF1 RYR2 KMT2D KIF3B DST PTPRC GMEB1 MACF1 ASCC3 UTRN GOLGB1	4.40e-07	591	132	13	15231748
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	DENND4A SPTBN1 CHD2 TTC3 RYR1 ZNF462 DST FAM120A XIRP2 SUPT16H MACF1 UTRN	4.71e-07	497	132	12	23414517
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTA1 SPTBN1 ITGB4 SPTBN4	5.82e-07	18	132	4	12119179
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	DST XIRP2 MACF1 HEATR5B	9.16e-07	20	132	4	21689717
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SUMO4 MACC1 MAML1 RRP15 CHD2 ODF2 PWWP2A SRRT DST ARID2 MED25 HLTF MACF1 ARPC5L ASCC3 HEATR5B DHX29 UTRN GOLGB1 ZNF574	9.82e-07	1497	132	20	31527615
Pubmed	Myogenin and class II HDACs control neurogenic muscle atrophy by inducing E3 ubiquitin ligases.	HDAC5 HDAC4 DST	1.06e-06	6	132	3	20887891
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TANC2 SEMG1 INTU RAD18 PHLDA1 SCEL RESF1 FAM120A FBXO5 ARID2 SUPT16H MACF1 FOXP1 ASCC3 PHLDB2 WDR62 ZNF574	1.20e-06	1116	132	17	31753913
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	TRERF1 RAD18 SPTBN1 RRP15 SPAG9 ODF2 SRRT KMT2D PTPRC HSF1 DHX29 PHLDB2 WDR62 MOCOS	1.58e-06	774	132	14	15302935
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TANC2 SEMA4G PCDHB16 SPTBN4 RESF1 ARID2	2.51e-06	101	132	6	10997877
Pubmed	A human MAP kinase interactome.	SHANK1 HDAC4 SPTBN1 TERF1 ITGB4 DST ARID2 MACF1 GCN1 WNK2 GOLGB1	2.69e-06	486	132	11	20936779
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	SEMG2 SUMO4 SPTBN1 ITGB4 TGM1 AP2M1 SUPT16H MACF1 ARPC5L GCN1 PHLDB2	2.80e-06	488	132	11	31324722
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	EFL1 TAS1R3 SPTA1 RYR2 EXOC5 METTL16 ACAP2	3.84e-06	168	132	7	30631154
Pubmed	METTL16 promotes glycolytic metabolism reprogramming and colorectal cancer progression.	YTHDF1 IGF2BP1 METTL16	4.41e-06	9	132	3	37340443
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	SUMO4 ESS2 SPAG9 ODF2 PWWP2A DST NFATC2IP SUPT16H MED25 LTBP1 ACAP2 UTRN	6.90e-06	645	132	12	25281560
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 HDAC5 HDAC4 MAML1 ZNF462 KMT2D RESF1 ARID2 FOXP1	8.37e-06	351	132	9	38297188
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TANC2 DENND4A HDAC5 HDAC4 DST MTMR3 UTRN COA7 PHLDB2 WDR62	8.44e-06	446	132	10	24255178
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	TANC2 RAD18 ESS2 HDAC5 RPAP3 MAML1 FYCO1 YTHDF1 SRRT NEK1 IGF2BP1 AP2M1 ARPC5L HEATR5B MOCOS	1.00e-05	1038	132	15	26673895
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	HDAC4 SPTBN4 AP2M1 DST RESF1 MACF1	1.08e-05	130	132	6	12421765
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SHANK1 TTC3 RYR2 YTHDF1 EXOC5 IGF2BP1 KIF3B FAM120A ASCC3 WNK2	1.14e-05	462	132	10	31138677
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	PPP1R14C CHD2 ERI2 TTC3 TERF1 THBS3 GCC2 CKAP2L DDHD2 KLHL8 HSF2 DHX29	1.28e-05	686	132	12	29987050
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	ZC3H8 SPTBN1 CHD2 YTHDF1 SRRT IGF2BP1 FAM120A SUPT16H MACF1 METTL16 ASCC3 GCN1 DHX29	1.31e-05	807	132	13	22681889
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	INTU HDAC4 ZC3H8 CHD2 TTC3 PCDHB16 ZNF462 SPTBN4 CFAP20DC FAM120A GCC2 VPS35L MACF1 FOXP1 UTRN WNK2 GOLGB1 MOCOS	1.41e-05	1489	132	18	28611215
Pubmed	Cloning and characterization of two mouse heat shock factors with distinct inducible and constitutive DNA-binding ability.	HSF1 HSF2	1.43e-05	2	132	2	1717345
Pubmed	Disruption of the Class IIa HDAC Corepressor Complex Increases Energy Expenditure and Lipid Oxidation.	HDAC5 HDAC4	1.43e-05	2	132	2	27626651
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	1.43e-05	2	132	2	11002341
Pubmed	Ganglioside GM1 mediates decapacitation effects of SVS2 on murine spermatozoa.	SEMG1 SEMG2	1.43e-05	2	132	2	18753612
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	1.43e-05	2	132	2	17259277
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	1.43e-05	2	132	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	1.43e-05	2	132	2	26009179
Pubmed	Expression of heat shock transcription factor 1 and its downstream target protein T-cell death associated gene 51 in the spinal cord of a mouse model of amyotrophic lateral sclerosis.	PHLDA1 HSF1	1.43e-05	2	132	2	23063459
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	1.43e-05	2	132	2	32899693
Pubmed	Heat shock transcription factor 1 localizes to sex chromatin during meiotic repression.	HSF1 HSF2	1.43e-05	2	132	2	20802198
Pubmed	Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans.	SEMG1 SEMG2	1.43e-05	2	132	2	19089943
Pubmed	The proteostasis guardian HSF1 directs the transcription of its paralog and interactor HSF2 during proteasome dysfunction.	HSF1 HSF2	1.43e-05	2	132	2	32607595
Pubmed	Gene structure of semenogelin I and II. The predominant proteins in human semen are encoded by two homologous genes on chromosome 20.	SEMG1 SEMG2	1.43e-05	2	132	2	1517240
Pubmed	Nuclear calcium signaling regulates nuclear export of a subset of class IIa histone deacetylases following synaptic activity.	HDAC5 HDAC4	1.43e-05	2	132	2	23364788
Pubmed	MD simulation of high-resolution X-ray structures reveals post-translational modification dependent conformational changes in HSF-DNA interaction.	HSF1 HSF2	1.43e-05	2	132	2	27882499
Pubmed	Integrin α6β4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes.	ITGB4 DST	1.43e-05	2	132	2	31006587
Pubmed	The structure of the semenogelin gene locus--nucleotide sequence of the intergenic and the flanking DNA.	SEMG1 SEMG2	1.43e-05	2	132	2	8654389
Pubmed	Seminal vesicle protein SVS2 is required for sperm survival in the uterus.	SEMG1 SEMG2	1.43e-05	2	132	2	24591616
Pubmed	Human Semenogelin 1 Promotes Sperm Survival in the Mouse Female Reproductive Tract.	SEMG1 SEMG2	1.43e-05	2	132	2	32486486
Pubmed	Crosstalk between HSF1 and HSF2 during the heat shock response in mouse testes.	HSF1 HSF2	1.43e-05	2	132	2	25450459
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	1.43e-05	2	132	2	15033925
Pubmed	Heat shock factor 2 (HSF2) contributes to inducible expression of hsp genes through interplay with HSF1.	HSF1 HSF2	1.43e-05	2	132	2	17213196
Pubmed	The cloning of a rapidly evolving seminal-vesicle-transcribed gene encoding the major clot-forming protein of mouse semen.	SEMG1 SEMG2	1.43e-05	2	132	2	8631362
Pubmed	Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cells.	HDAC5 HDAC4	1.43e-05	2	132	2	29472387
Pubmed	Elevated expression of heat shock factor (HSF) 2A stimulates HSF1-induced transcription during stress.	HSF1 HSF2	1.43e-05	2	132	2	12813038
Pubmed	Estrogen dependent expression of heat shock transcription factor: implications for uterine synthesis of heat shock proteins.	HSF1 HSF2	1.43e-05	2	132	2	7748806
Pubmed	[Isolation and structure determination of two peptides occurring in human seminal plasma].	SEMG1 SEMG2	1.43e-05	2	132	2	2757795
Pubmed	Comprehensive analysis of human tissues reveals unique expression and localization patterns of HSF1 and HSF2.	HSF1 HSF2	1.43e-05	2	132	2	38458311
Pubmed	Isolation and characterization of the major gel proteins in human semen, semenogelin I and semenogelin II.	SEMG1 SEMG2	1.43e-05	2	132	2	8665951
Pubmed	SEMG1/2 augment energy metabolism of tumor cells.	SEMG1 SEMG2	1.43e-05	2	132	2	33311447
Pubmed	Distribution and tissue expression of semenogelin I and II in man as demonstrated by in situ hybridization and immunocytochemistry.	SEMG1 SEMG2	1.43e-05	2	132	2	8833737
Pubmed	Semen-coagulating protein, SVS2, in mouse seminal plasma controls sperm fertility.	SEMG1 SEMG2	1.43e-05	2	132	2	17123940
Pubmed	Unraveling complex interplay between heat shock factor 1 and 2 splicing isoforms.	HSF1 HSF2	1.43e-05	2	132	2	23418516
Pubmed	Structures of HSF2 reveal mechanisms for differential regulation of human heat-shock factors.	HSF1 HSF2	1.43e-05	2	132	2	26727490
Pubmed	Essential requirement for both hsf1 and hsf2 transcriptional activity in spermatogenesis and male fertility.	HSF1 HSF2	1.43e-05	2	132	2	14994269
Pubmed	A Mettl16/m6A/mybl2b/Igf2bp1 axis ensures cell cycle progression of embryonic hematopoietic stem and progenitor cells.	IGF2BP1 METTL16	1.43e-05	2	132	2	38605226
Pubmed	Heterotrimerization of heat-shock factors 1 and 2 provides a transcriptional switch in response to distinct stimuli.	HSF1 HSF2	1.43e-05	2	132	2	19129477
Pubmed	Evolution of the hominoid semenogelin genes, the major proteins of ejaculated semen.	SEMG1 SEMG2	1.43e-05	2	132	2	14629036
Pubmed	Semenogelin I and II, the predominant human seminal plasma proteins, are also expressed in non-genital tissues.	SEMG1 SEMG2	1.43e-05	2	132	2	12200457
Pubmed	Quantification of seminal plasma motility inhibitor/semenogelin in human seminal plasma.	SEMG1 SEMG2	1.43e-05	2	132	2	14581514
Pubmed	Nitric oxide modulates chromatin folding in human endothelial cells via protein phosphatase 2A activation and class II histone deacetylases nuclear shuttling.	HDAC5 HDAC4	1.43e-05	2	132	2	17975112
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	1.43e-05	2	132	2	30542613
Pubmed	Heat shock factor 2 is required for maintaining proteostasis against febrile-range thermal stress and polyglutamine aggregation.	HSF1 HSF2	1.43e-05	2	132	2	21813737
Pubmed	Isolation of a cDNA for HSF2: evidence for two heat shock factor genes in humans.	HSF1 HSF2	1.43e-05	2	132	2	1871106
Pubmed	Class IIa HDACs regulate learning and memory through dynamic experience-dependent repression of transcription.	HDAC5 HDAC4	1.43e-05	2	132	2	31375688
Pubmed	Class II histone deacetylases downregulate GLUT4 transcription in response to increased cAMP signaling in cultured adipocytes and fasting mice.	HDAC5 HDAC4	1.43e-05	2	132	2	22403301
Pubmed	Conformational change of erythroid alpha-spectrin at the tetramerization site upon binding beta-spectrin.	SPTA1 SPTBN1	1.43e-05	2	132	2	17905835
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	1.43e-05	2	132	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	1.43e-05	2	132	2	11673493
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	1.43e-05	2	132	2	11673462
Pubmed	Seminal vesicle secretion 2 acts as a protectant of sperm sterols and prevents ectopic sperm capacitation in mice.	SEMG1 SEMG2	1.43e-05	2	132	2	25395676
Pubmed	The pan-cancer analysis of the two types of uterine cancer uncovered clinical and prognostic associations with m6A RNA methylation regulators.	IGF2BP1 METTL16	1.43e-05	2	132	2	34110327
Pubmed	Control of cardiac growth by histone acetylation/deacetylation.	HDAC5 HDAC4	1.43e-05	2	132	2	16397154
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	1.43e-05	2	132	2	25370123
Pubmed	Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells.	HSF1 HSF2	1.43e-05	2	132	2	23959860
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	1.43e-05	2	132	2	18618700
Pubmed	Peptides released by physiological cleavage of semen coagulum proteins form amyloids that enhance HIV infection.	SEMG1 SEMG2	1.43e-05	2	132	2	22177559
Pubmed	Functional preservation of duplicated pair for RSVS III gene in the REST locus of rat 3q42.	SEMG1 SEMG2	1.43e-05	2	132	2	15582586
Pubmed	Expression of semenogelins I and II and its prognostic significance in human prostate cancer.	SEMG1 SEMG2	1.43e-05	2	132	2	21557275
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPAP3 SPTBN1 RRP15 CHD2 SRRT TGM1 AP2M1 DST FAM120A SUPT16H HLTF MACF1 ASCC3 GCN1 DHX29 UTRN PHLDB2	1.53e-05	1353	132	17	29467282
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	ESS2 MAML1 ODF2 ZNF462 AP2M1 RESF1 SUPT16H	2.36e-05	222	132	7	37071664
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HDAC5 SPAG9 ZNF462 DST MACF1 KLHL8 GCN1	2.57e-05	225	132	7	12168954
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	SHANK1 TANC2 IQGAP2 SPTA1 SPTBN1 SPTBN4 SRRT TGM1 AP2M1 DST FAM120A OSBPL10 MACF1 ARPC5L DHX29 UTRN WNK2	3.10e-05	1431	132	17	37142655
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	IGF2BP1 KMT2D DST SUPT16H MACF1 EEA1 GOLGB1	3.30e-05	234	132	7	36243803
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RRP15 SRRT IGF2BP1 DST SUPT16H CKAP2L MACF1 EEA1 ASCC3 HEATR5B GCN1 UTRN GOLGB1 PHLDB2	3.68e-05	1024	132	14	24711643
Pubmed	Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening.	MACC1 SPTA1 NCF1 PSTPIP1	3.99e-05	50	132	4	19807924
Interaction	KDM1A interactions	TRERF1 HDAC5 RPAP3 FYCO1 TERF1 ZNF462 NEK1 AP2M1 KMT2D DST RESF1 GCC2 SUPT16H FOXP1 SNAPC1 ASCC3 HSF1 GCN1 UTRN GOLGB1 WDR62	5.53e-07	941	129	21	int:KDM1A
Interaction	EGR2 interactions	TRERF1 HDAC5 HDAC4 MAML1 ZNF462 KMT2D RESF1 ARID2 FOXP1	1.58e-06	171	129	9	int:EGR2
Interaction	SOX2 interactions	TRERF1 SEMG1 SEMG2 SPTBN1 MAML1 RRP15 SCEL TTC3 ITGB4 RYR1 COPS7A YTHDF1 ZNF462 IGF2BP1 AP2M1 KMT2D FAM120A ARID2 SUPT16H CKAP2L MACF1 FOXP1 ARPC5L ASCC3 GCN1	3.28e-06	1422	129	25	int:SOX2
Interaction	PHF21A interactions	HDAC5 RPAP3 NEK1 KMT2D DST RESF1 GCC2 ASCC3 UTRN GOLGB1 WDR62	1.32e-05	343	129	11	int:PHF21A
Interaction	SP7 interactions	TRERF1 ESS2 MAML1 SRRT IGF2BP1 KMT2D NKX2-4 ARID2 FOXP1 FILIP1L	2.66e-05	304	129	10	int:SP7
Interaction	YWHAE interactions	TANC2 MACC1 DENND4A RAD18 HDAC5 HDAC4 RPAP3 TTC3 TMCC3 NEK1 IGF2BP1 DST GCC2 MTMR3 MACF1 LTBP1 HSF1 ACAP2 WNK2 PHLDB2 WDR62	4.70e-05	1256	129	21	int:YWHAE
GeneFamily	EF-hand domain containing\|Spectrins	SPTA1 SPTBN1 SPTBN4	3.11e-06	7	82	3	1113
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	6.08e-05	3	82	2	287
GeneFamily	Histone deacetylases, class IIA	HDAC5 HDAC4	1.21e-04	4	82	2	992
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SPTBN1 SPTBN4 OSBPL10 PLEKHH2 ACAP2 PHLDB2	3.47e-04	206	82	6	682
GeneFamily	Zinc fingers FYVE-type\|Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors	FYCO1 MTMR3 EEA1	3.69e-04	31	82	3	81
GeneFamily	EF-hand domain containing	SPTA1 RYR2 CAPN11 GUCA1C DST MACF1	4.80e-04	219	82	6	863
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	5.59e-04	8	82	2	939
GeneFamily	DNA helicases	CHD2 ASCC3	2.64e-03	17	82	2	1167
GeneFamily	PWWP domain containing	ZCWPW1 PWWP2A	4.43e-03	22	82	2	1147
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	RAD18 IQGAP2 RPAP3 ZC3H8 ATL1 NEK1 RESF1 GCC2 HLTF OSBPL10 SNAPC1 EEA1 DHX29 GOLGB1	5.46e-06	656	131	14	M18979
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	RAD18 MCMBP ZCWPW1 RPAP3 ZC3H8 KIAA0586 RRP15 TERF1 COPS7A ZNF462 CFAP20DC IGF2BP1 FBXO5 NFATC2IP RANGRF SUPT16H HLTF DDHD2 METTL16 HSF2 COA7	2.43e-08	822	129	21	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#2	RPAP3 KIAA0586 CHD2 ODF2 NEK1 FAM120A ARID2 MACF1 MRNIP HEATR5B HSF2 ACAP2 DHX29 UTRN GOLGB1	1.77e-06	564	129	15	Facebase_RNAseq_e9.5_Mandibular Arch_2500_K2
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	RAD18 ZCWPW1 RPAP3 ZC3H8 KIAA0586 RRP15 TDRD1 TERF1 COPS7A CFAP20DC NFATC2IP RANGRF HLTF DDHD2 METTL16 HSF2 COA7	8.41e-06	810	129	17	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	TANC2 DENND4A RAD18 MCMBP ZCWPW1 ZC3H8 TDRD1 TERF1 ATL1 NEK1 CFAP20DC NFATC2IP NETO2 SUPT16H SNAPC1 DDHD2 HSF2	9.87e-06	820	129	17	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000	RAD18 ZCWPW1 RPAP3 ZC3H8 RRP15 TERF1 COPS7A CFAP20DC FBXO5 NFATC2IP RANGRF HLTF DDHD2 METTL16 HSF2 COA7	2.64e-05	795	129	16	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_top-relative-expression-ranked_1000	RAD18 ZCWPW1 ZC3H8 KIAA0586 RRP15 TERF1 COPS7A CFAP20DC IGF2BP1 FBXO5 NFATC2IP RANGRF HLTF DDHD2 HSF2 COA7	2.80e-05	799	129	16	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	TANC2 RAD18 IQGAP2 RYR2 IGF2BP1 RESF1 SUPT16H FOXP1 ASCC3 GCN1 UTRN	3.14e-05	397	129	11	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#3	KIAA0586 CHD2 GCC2 SUPT16H CKAP2L MACF1 HEATR5B PHLDB2 FILIP1L	7.35e-05	291	129	9	Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000_K3
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000	RAD18 ZCWPW1 RRP15 TERF1 COPS7A CFAP20DC IGF2BP1 FBXO5 NFATC2IP RANGRF HLTF DDHD2 METTL16 HSF2 COA7	8.11e-05	781	129	15	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#5_top-relative-expression-ranked_200	KRT4 MACC1 SCEL DST	9.07e-05	39	129	4	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200_k5
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#4_top-relative-expression-ranked_1000	ZC3H8 KIAA0586 COPS7A NFATC2IP RANGRF METTL16 HSF2 COA7	1.22e-04	243	129	8	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k4_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	RPAP3 KIAA0586 CHD2 ODF2 NEK1 NETO2 GCC2 SUPT16H CKAP2L	1.22e-04	311	129	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_1000	RAD18 KIAA0586 RRP15 TERF1 COPS7A CFAP20DC NFATC2IP RANGRF HLTF HSF2 COA7	1.24e-04	463	129	11	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k3_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#3_top-relative-expression-ranked_100	KRT4 MACC1 DST	1.98e-04	19	129	3	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_100_k3
CoexpressionAtlas	dev gonad_e12.5_M_GermCellTestis_Oct_k-means-cluster#2_top-relative-expression-ranked_1000	RAD18 RPAP3 ZC3H8 TERF1 CFAP20DC NFATC2IP DDHD2 HSF2	2.25e-04	266	129	8	gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_k2_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	IQGAP2 NCF1 KIAA0586 FYCO1 ODF2 ERI2 TDRD1 ZNF462 IGF2BP1 NETO2 GCC2 SUPT16H CKAP2L MACF1 HSF2 WNK2 WDR62	2.36e-04	1060	129	17	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	FacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#4	RPAP3 KIAA0586 ODF2 FAM120A MACF1 HEATR5B UTRN	2.46e-04	203	129	7	Facebase_RNAseq_e9.5_Mandibular Arch_1000_K4
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPTBN1 TMCC3 DST MACF1 FOXP1 UTRN GOLGB1 PHLDB2 FILIP1L	5.36e-09	190	131	9	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TANC2 TTC3 DST FAM120A GCC2 FOXP1 EEA1 UTRN GOLGB1	8.02e-09	199	131	9	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 PTPRC GCC2 MACF1 FOXP1 ASCC3 UTRN FILIP1L	7.57e-08	184	131	8	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC3 RAD51AP2 DST FAM120A MACF1 ASCC3 GOLGB1 PHLDB2	1.18e-07	195	131	8	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTC3 RAD51AP2 DST FAM120A MACF1 ASCC3 GOLGB1 PHLDB2	1.18e-07	195	131	8	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	(04)_Interm._basal>secr.-(2)_GFP_FOXI1\|(04)_Interm._basal>secr. / shred by cell type by condition	TANC2 IQGAP2 TTC3 FAM120A GCC2 FOXP1 EEA1 GOLGB1	1.38e-07	199	131	8	53ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	HDAC4 CHD2 SPAG9 DST KCNJ10 MTMR3 GOLGB1	9.59e-07	177	131	7	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	DENND4A CHD2 PTPRC ARID2 MACF1 UTRN GOLGB1	1.43e-06	188	131	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MACC1 PPP1R14C ZNF462 PKHD1 OSBPL10 PLEKHH2 UTRN	1.43e-06	188	131	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SPTBN1 CHD2 TTC3 RESF1 GCC2 MACF1 FOXP1	1.83e-06	195	131	7	4bdedd924564a260841a9153604026b57487c83d
ToppCell	facs-Brain_Myeloid-Hippocampus\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TANC2 KRT4 NCF1 PWWP2A DST MACF1 ACAP2	1.83e-06	195	131	7	a1478021a3ed0e779716393124ca2a7770c433b7
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SPTBN1 CHD2 TTC3 RESF1 GCC2 MACF1 FOXP1	1.96e-06	197	131	7	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	TTC3 FAM120A GCC2 FOXP1 EEA1 GOLGB1 PHLDB2	2.09e-06	199	131	7	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	TANC2 IQGAP2 TTC3 FAM120A GCC2 EEA1 GOLGB1	2.09e-06	199	131	7	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	(05)_Secretory-(2)_GFP_FOXI1\|(05)_Secretory / shred by cell type by condition	TANC2 TTC3 FAM120A GCC2 OSBPL10 EEA1 GOLGB1	2.09e-06	199	131	7	d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CHD2 SPAG9 PTPRC RESF1 MACF1 UTRN GOLGB1	2.16e-06	200	131	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	CHD2 PTPRC PKHD1 MACF1 UTRN GOLGB1	3.00e-06	135	131	6	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SPTBN1 CHD2 PTPRC MACF1 FOXP1 UTRN	8.56e-06	162	131	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DENND4A CHD2 PTPRC MACF1 UTRN GOLGB1	1.16e-05	171	131	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	cellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PPP1R14C ITGB4 RYR1 TGM1 DST PKHD1	1.20e-05	172	131	6	e9095c3dac66cf93d31f5f88364b565abacb1e2d
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TANC2 MACC1 CHD2 MACF1 WNK2 GOLGB1	1.51e-05	179	131	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	Ciliated_cells-A-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	SEMA4G KIF9 FBXO5 PLEKHH2 WNK2 MOCOS	1.51e-05	179	131	6	1c41314b6fcfcac8d62034e7037570120d58f20f
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 PTPRC GCC2 MACF1 FOXP1 FILIP1L	1.66e-05	182	131	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD2 SERP1 PTPRC MACF1 FOXP1 FILIP1L	1.66e-05	182	131	6	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD2 SERP1 PTPRC MACF1 FOXP1 FILIP1L	1.71e-05	183	131	6	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD2 SERP1 PTPRC MACF1 FOXP1 FILIP1L	1.71e-05	183	131	6	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACC1 SCEL PKHD1 UTRN PHLDB2 MOCOS	1.76e-05	184	131	6	42ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 PTPRC GCC2 MACF1 FOXP1 FILIP1L	1.82e-05	185	131	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACC1 SCEL PKHD1 UTRN PHLDB2 MOCOS	1.88e-05	186	131	6	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	DST PTPRC GCC2 UTRN GOLGB1 FILIP1L	1.93e-05	187	131	6	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPAG9 ITGB4 CFAP20DC GCC2 FOXP1 LTBP1	2.11e-05	190	131	6	9b0ad888eb20acc011904d8593bc32bdef18d050
ToppCell	LAM-Epithelial-AT1\|Epithelial / Condition, Lineage and Cell class	KRT4 SPTBN1 SCEL DST PLEKHH2 PHLDB2	2.18e-05	191	131	6	3457e15d1e9b36a78363d46b320c4ec46b40290a
ToppCell	COPD-Lymphoid-T\|World / Disease state, Lineage and Cell class	TRERF1 NUGGC IQGAP2 FYCO1 RYR2 PTPRC	2.24e-05	192	131	6	eb4909574fb5fc91399463523e2737095773200a
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DENND4A HDAC4 CHD2 PTPRC MACF1 FOXP1	2.24e-05	192	131	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating2_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KIAA0586 ODF2 FBXO5 ARHGEF39 CKAP2L WDR62	2.24e-05	192	131	6	026f3e38970bea1e6e8d76a4e2becdfb8484b2ff
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SPAG9 ITGB4 CFAP20DC GCC2 FOXP1 LTBP1	2.24e-05	192	131	6	c157981b9a179925edcaabc0cb3b8805f0929004
ToppCell	droplet-Fat-Mat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 ITGB4 TMCC3 RYR2 DST UTRN	2.31e-05	193	131	6	54024a373e42e1c0bcc327dc084564b83b63a9d4
ToppCell	droplet-Fat-Mat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 ITGB4 TMCC3 RYR2 DST UTRN	2.31e-05	193	131	6	81d908594d2983ba7e7c1ec25afdde4315d9690e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	RYR2 DST MACF1 LTBP1 PLEKHH2 PHLDB2	2.31e-05	193	131	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	moderate-Epithelial-FOXN4+\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP20DC KIF9 NETO2 SNAPC1 UTRN WDR62	2.38e-05	194	131	6	dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MACC1 DST PKHD1 OSBPL10 PLEKHH2	2.45e-05	195	131	6	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TANC2 MACC1 DST PKHD1 OSBPL10 PLEKHH2	2.45e-05	195	131	6	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Proliferating-Cycling_Progenitors\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	IQGAP2 FBXO5 CKAP2L LTBP1 UTRN WDR62	2.52e-05	196	131	6	5905f0e3061a6b98b7a33d64c782c3dda2cd51ef
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	INTU RYR2 DST MACF1 LTBP1 PLEKHH2	2.59e-05	197	131	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RYR2 DST MACF1 LTBP1 PLEKHH2 FILIP1L	2.59e-05	197	131	6	94a9603cbd3516fbcce871909693b88f20d41713
ToppCell	(11)_FOXN4+-(2)_GFP_FOXI1\|(11)_FOXN4+ / shred by cell type by condition	TANC2 TTC3 GCC2 DHX29 UTRN GOLGB1	2.67e-05	198	131	6	76d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell	(10)_Ciliated-(2)_GFP_FOXI1\|(10)_Ciliated / shred by cell type by condition	TTC3 RESF1 FAM120A GCC2 EEA1 GOLGB1	2.74e-05	199	131	6	61b1ed2db71b96157b92b7535d1955a4033098da
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	DST FBXO5 ARHGEF39 CKAP2L MACF1 PLEKHH2	2.74e-05	199	131	6	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	TRERF1 NUGGC NCF1 PSTPIP1 PTPRC RESF1	2.74e-05	199	131	6	5a29db2610ba06a2248325a16cad755d20debf2c
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SCEL PKHD1 UTRN GOLGB1 PHLDB2 MOCOS	2.74e-05	199	131	6	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	TTC3 FAM120A GCC2 FOXP1 EEA1 GOLGB1	2.74e-05	199	131	6	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	KIAA0586 ODF2 FBXO5 ARHGEF39 CKAP2L WDR62	2.74e-05	199	131	6	ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	IQGAP2 MAML1 FAM120A FOXP1 LTBP1 UTRN	2.74e-05	199	131	6	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	IQGAP2 SPTBN1 DST PLEKHH2 GOLGB1 FILIP1L	2.74e-05	199	131	6	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TTC3 FAM120A GCC2 EEA1 DHX29 GOLGB1	2.74e-05	199	131	6	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPTBN1 DST RESF1 MACF1 FOXP1 UTRN	2.82e-05	200	131	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	SCEL PKHD1 UTRN GOLGB1 PHLDB2 MOCOS	2.82e-05	200	131	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SCEL PKHD1 UTRN GOLGB1 PHLDB2 MOCOS	2.82e-05	200	131	6	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	Bronchus_Control_(B.)-Epithelial-TX-Basal_3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	PHLDA1 ITGB4 RYR1 TGM1 DST PHLDB2	2.82e-05	200	131	6	06b59ee536414d1f73c1e17cdfd7c3f2259b9bef
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	IQGAP2 SPAG9 RESF1 MACF1 UTRN GOLGB1	2.82e-05	200	131	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	LA-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	RYR2 IGF2BP1 XIRP2 ARHGEF39 TSKS	5.70e-05	139	131	5	9e2a84d5ed7232b70eadbba754d9ca13f2d50fe9
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CHD2 KMT2D PTPRC MACF1 GOLGB1	7.43e-05	147	131	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	OTP FBXO5 NKX2-4 ARHGEF39 CKAP2L	7.68e-05	148	131	5	b9d3421c2eb8e748e9508c1cbd1cb4f96e23db5a
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4\|Hippocampus / BrainAtlas - Mouse McCarroll V32	OTP FBXO5 NKX2-4 ARHGEF39 CKAP2L	7.68e-05	148	131	5	2a7671dc27afbdf6a92d976c5f2b728bd18dd609
ToppCell	droplet-Bladder-nan-3m-Hematologic-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NCF1 PCDHB16 PTPRC KCNJ10 CKAP2L	8.44e-05	151	131	5	a7b1a60d68f0ed17022fe4c97af64f9f08d39fa3
ToppCell	P15-Epithelial-epithelial_progenitor_cell-epi_progenitor\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	TANC2 PPP1R14C SEMA4G ATL1 TGM1	1.08e-04	159	131	5	a4bfd59c53237964fc24a24de5c1925fdd01db99
ToppCell	356C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ITGB4 RYR2 DST MACF1 PLEKHH2	1.11e-04	160	131	5	0293b244c063a62819690bf22bbc2681f8d15252
ToppCell	356C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	ITGB4 RYR2 DST MACF1 PLEKHH2	1.11e-04	160	131	5	3eaae86fa08f7651021316f8e5811bf48055591e
ToppCell	droplet-Heart-nan-18m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSTPIP1 RYR1 ARHGEF39 CKAP2L WDR62	1.17e-04	162	131	5	7f425a3983325a5a3ea33f812b15aa010cc55de0
ToppCell	facs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H8 RANGRF MTMR3 OSBPL10 CKAP2L	1.24e-04	164	131	5	1d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCell	facs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZC3H8 RANGRF MTMR3 OSBPL10 CKAP2L	1.24e-04	164	131	5	bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCell	Sigmoid-Macrophage-Macrophage\|Macrophage / Region, Cell class and subclass	MACC1 IQGAP2 NCF1 UTRN FILIP1L	1.39e-04	168	131	5	bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCell	Mild/Remission-B_naive-4\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DENND4A PTPRC MACF1 FOXP1 HEATR5B	1.43e-04	169	131	5	c3a6179a64589a370108fea809b157839347759c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RAD18 CFAP20DC NETO2 CKAP2L WDR62	1.43e-04	169	131	5	e7514956b2e4298222ec443f98b2f5289451786e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ERI2 FBXO5 ARHGEF39 CKAP2L WDR62	1.43e-04	169	131	5	e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IQGAP2 TERF1 PTPRC ARHGEF39 CKAP2L	1.47e-04	170	131	5	a0d6466e00bd3dc07f644ba3f87d5b421fd479d5
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGB4 DST KCNQ1 FOXP1 FILIP1L	1.47e-04	170	131	5	af8b56555cbd5a1016ab9ec2ce88225c58c89648
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PSTPIP1 PTPRC ARHGEF39 CKAP2L WDR62	1.51e-04	171	131	5	55c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	CFAP20DC FBXO5 CKAP2L LTBP1 TSKS	1.55e-04	172	131	5	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITGB4 DST KCNQ1 FOXP1 FILIP1L	1.55e-04	172	131	5	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	E16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TERF1 SPTBN4 ARHGEF39 CKAP2L WDR62	1.64e-04	174	131	5	7fb7bdf62563f2102fb38618b503eb2817b6594f
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST MACF1 LTBP1 PLEKHH2 FILIP1L	1.68e-04	175	131	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PPP1R14C CFAP20DC FBXO5 CKAP2L WDR62	1.68e-04	175	131	5	fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DENND4A DST PTPRC RESF1 MACF1	1.68e-04	175	131	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|368C / Donor, Lineage, Cell class and subclass (all cells)	PPP1R14C CFAP20DC FBXO5 CKAP2L WDR62	1.68e-04	175	131	5	36c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RYR2 XIRP2 SUPT16H MACF1 ASCC3	1.73e-04	176	131	5	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PPP1R14C ZNF462 PKHD1 PLEKHH2 UTRN	1.73e-04	176	131	5	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRERF1 IQGAP2 NCF1 RYR1 PTPRC	1.78e-04	177	131	5	7bc92314b22a876296a4e2db51e7fb0fdfd69379
ToppCell	facs-Skin-Anagen-24m-Epithelial-actively_dividing_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERI2 ARHGEF39 CKAP2L MRNIP WDR62	1.78e-04	177	131	5	8a0f0fbb06cdacb99a3fdba0da3e0494b891db4f
ToppCell	facs-Skin-Anagen-24m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERI2 ARHGEF39 CKAP2L MRNIP WDR62	1.78e-04	177	131	5	e9d7682517fb30fd2ad535d59779d718a7024c13
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPTBN1 DST MACF1 UTRN PHLDB2	1.82e-04	178	131	5	ad3de3e03a401dac64431a541899445262246347
ToppCell	normal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SPTBN1 CHD2 RESF1 GCC2 EEA1	1.82e-04	178	131	5	fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell	droplet-Kidney-KIDNEY-1m-Lymphocytic-CD45____B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EFL1 DENND4A RYR2 HLTF FOXP1	1.87e-04	179	131	5	69c74b2ff43b43653005807654953daf21f932ec
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RRP15 RYR1 CFAP20DC FBXO5 CKAP2L	1.87e-04	179	131	5	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRERF1 IQGAP2 NCF1 RYR1 PTPRC	1.87e-04	179	131	5	33ed9270d257895ff3b40df2c1af878119c9f492
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-dendritic_type_2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TRERF1 IQGAP2 RYR1 PTPRC ARHGEF39	1.87e-04	179	131	5	b7a2429d07d7146b32b3552a5f2a2542105a71e0
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	KRT4 SCEL DST PLEKHH2 PHLDB2	1.87e-04	179	131	5	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MACC1 SCEL PKHD1 PHLDB2 MOCOS	1.87e-04	179	131	5	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	Adult-Immune-T_lymphocyte-D122\|Adult / Lineage, Cell type, age group and donor	TRERF1 NUGGC IQGAP2 PTPRC RESF1	1.92e-04	180	131	5	06c371d0f0c5a7b234dd143e98800e19af95a8b5
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT4 SCEL ITGB4 TGM1 DST	1.97e-04	181	131	5	6b43dcaeeb02ad5900772b6f16f1581847050e38
Computational	Genes upregulated in subsets of cells of a given type within various tumors	CHD2 RESF1 GCC2 MACF1 UTRN GOLGB1	2.03e-06	49	84	6	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Drug	plakin	SPTA1 SPTBN1 ITGB4 SPTBN4 DST MACF1 UTRN	4.48e-07	82	130	7	CID000018752
Drug	Idoxuridine [54-42-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	KIAA0586 TDRD1 ITGB4 LTBP1 EEA1 METTL16 HSF2 GOLGB1 WDR62	1.78e-06	194	130	9	1480_DN
Drug	mono-(2-ethylhexyl)phthalate	TMPRSS15 IQGAP2 SPTA1 ITGB4 SEMA4G RYR1 SPTBN4 TGM1 NEK1 IGF2BP1 DST PKHD1 LTBP1 ASCC3 WNK2	5.48e-06	658	130	15	ctd:C016599
Drug	geldanamycin	SPTBN1 TTC3 SRRT DST RESF1 SUPT16H EEA1 METTL16 HSF1 ACAP2 PHLDB2	9.55e-06	371	130	11	ctd:C001277
Drug	Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A	SPTBN1 SPAG9 ITGB4 SRRT EXOC5 MED25 WDR62 ZNF574	1.73e-05	196	130	8	3206_DN
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	TMPRSS15 MCMBP MAML1 SRRT NEK1 THBS3 METTL16 ZNF574	1.80e-05	197	130	8	2783_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	TDRD1 ITGB4 NEK1 MTMR3 LTBP1 UTRN WDR62 ZNF574	1.80e-05	197	130	8	1496_DN
Drug	Spironolactone [52-01-7]; Down 200; 9.6uM; PC3; HT_HG-U133A	TMPRSS15 HDAC5 PHLDA1 ODF2 SEMA4G RYR2 NEK1 GMEB1	1.93e-05	199	130	8	5781_DN
Drug	ADPribulose	SPTA1 SPTBN1 SPTBN4	4.99e-05	13	130	3	CID000197570
Drug	PRODAN	SPTA1 SPTBN1 SPTBN4	7.87e-05	15	130	3	CID000028127
Drug	TG-1	INTU TMPRSS15 TGM1	7.87e-05	15	130	3	CID000060499
Drug	cis-diammineplatinum(II	RYR1 RYR2	9.67e-05	3	130	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR1 RYR2	9.67e-05	3	130	2	CID002750949
Drug	8N3-cADPR	RYR1 RYR2	9.67e-05	3	130	2	CID000127713
Drug	aminodantrolene	RYR1 RYR2	9.67e-05	3	130	2	CID009570289
Drug	2-hydroxycarbazole	RYR1 RYR2	9.67e-05	3	130	2	CID000093551
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR2	9.67e-05	3	130	2	CID005748312
Drug	Wang resin	SPTA1 DST	9.67e-05	3	130	2	CID000070043
Drug	Prochlorperazine dimaleate [84-02-6]; Down 200; 6.6uM; MCF7; HT_HG-U133A	SPAG9 ZNF227 ITGB4 EXOC5 THBS3 HSF2 UTRN	9.84e-05	186	130	7	5010_DN
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; PC3; HT_HG-U133A	TANC2 ZCWPW1 SPTBN1 ODF2 EXOC5 GMEB1 UTRN	1.09e-04	189	130	7	3788_DN
Drug	Famprofazone [22881-35-2]; Down 200; 10.6uM; PC3; HT_HG-U133A	PHLDA1 SPAG9 SRRT NEK1 EXOC5 MED25 UTRN	1.20e-04	192	130	7	3753_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 1uM; PC3; HT_HG-U133A	PHLDA1 SPTBN1 SPAG9 ITGB4 EXOC5 HSF2 UTRN	1.20e-04	192	130	7	4334_DN
Drug	0316684-0000 [391209-55-5]; Up 200; 10uM; PC3; HT_HG-U133A	HDAC4 PHLDA1 RRP15 ITGB4 NEK1 ASCC3 HSF2	1.24e-04	193	130	7	7098_UP
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A	DENND4A ZNF227 EXOC5 EEA1 METTL16 HSF2 FILIP1L	1.28e-04	194	130	7	7189_UP
Drug	Flutamide [13311-84-7]; Down 200; 14.4uM; MCF7; HT_HG-U133A	SPTBN1 ITGB4 NEK1 FAM120A LTBP1 EEA1 METTL16	1.28e-04	194	130	7	4361_DN
Drug	Glafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; MCF7; HT_HG-U133A	ZCWPW1 RRP15 SPAG9 SRRT THBS3 MRNIP METTL16	1.32e-04	195	130	7	7018_DN
Drug	Antazoline hydrochloride [2508-72-7]; Down 200; 13.2uM; MCF7; HT_HG-U133A	ZCWPW1 ZNF227 ITGB4 SEMA4G THBS3 MED25 WDR62	1.32e-04	195	130	7	3173_DN
Drug	Propofol [2078-54-8]; Down 200; 22.4uM; HL60; HT_HG-U133A	TANC2 ZCWPW1 PHLDA1 SPTBN1 ITGB4 MRNIP EEA1	1.32e-04	195	130	7	3048_DN
Drug	Vancomycin hydrochloride [1404-93-9]; Down 200; 2.6uM; MCF7; HT_HG-U133A	DENND4A SPTBN1 TDRD1 ZNF623 NEK1 MTMR3 FILIP1L	1.36e-04	196	130	7	4423_DN
Drug	Cephalexin monohydrate [23325-78-2]; Down 200; 11uM; MCF7; HT_HG-U133A	EFL1 SPTBN1 SPAG9 EXOC5 MED25 MACF1 METTL16	1.36e-04	196	130	7	2628_DN
Drug	Retrorsine [480-54-6]; Up 200; 11.4uM; HL60; HT_HG-U133A	ZCWPW1 CHD2 SEMA4G SRRT MED25 LTBP1 UTRN	1.41e-04	197	130	7	2129_UP
Drug	Probucol [23288-49-5]; Down 200; 7.8uM; PC3; HT_HG-U133A	DENND4A MCMBP ZCWPW1 SPTBN1 RYR2 MED25 TSKS	1.41e-04	197	130	7	4666_DN
Drug	Metolazone [17560-51-9]; Down 200; 11uM; HL60; HG-U133A	NEK1 FAM120A NFATC2IP GMEB1 DDHD2 ASCC3 ACAP2	1.41e-04	197	130	7	2014_DN
Drug	Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A	PHLDA1 SPTBN1 MAML1 SRRT UTRN WDR62 FILIP1L	1.41e-04	197	130	7	6100_DN
Drug	Nimesulide [51803-78-2]; Down 200; 13uM; MCF7; HT_HG-U133A	PHLDA1 SPTBN1 RYR2 SRRT LTBP1 METTL16 WDR62	1.41e-04	197	130	7	2275_DN
Drug	Reserpinic acid hydrochloride; Down 200; 9.2uM; MCF7; HT_HG-U133A	ZCWPW1 PHLDA1 KIAA0586 FYCO1 RYR2 MACF1 MRNIP	1.45e-04	198	130	7	7323_DN
Drug	Procainamide hydrochloride [614-39-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	SHANK1 TMPRSS15 HDAC5 PHLDA1 SPTA1 SPTBN1 WDR62	1.45e-04	198	130	7	5663_UP
Drug	Dosulepin hydrochloride [897-15-4]; Down 200; 12uM; PC3; HT_HG-U133A	KRT4 MCMBP PHLDA1 ITGB4 SRRT METTL16 UTRN	1.50e-04	199	130	7	7284_DN
Drug	Proglumide [6620-60-6]; Up 200; 12uM; HL60; HT_HG-U133A	ZCWPW1 SEMA4G THBS3 MED25 MTMR3 MRNIP TSKS	1.50e-04	199	130	7	2363_UP
Drug	5162773; Up 200; 7uM; MCF7; HT_HG-U133A_EA	PHLDA1 ZNF227 ITGB4 SRRT THBS3 METTL16 WDR62	1.50e-04	199	130	7	892_UP
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	HDAC5 ZNF623 SEMA4G THBS3 MED25 MTMR3 MRNIP	1.50e-04	199	130	7	4543_DN
Drug	Naproxen [22204-53-1]; Up 200; 17.4uM; HL60; HT_HG-U133A	ZCWPW1 ESS2 ITGB4 RYR2 MED25 KCNQ1 COA7	1.54e-04	200	130	7	1869_UP
Disease	red blood cell density measurement	DENND4A SPTA1 SPTBN1 COPS7A ZNF462 TGM1 THBS3 DST PTPRC ARID2 PKHD1 FOXP1 KLHL8 METTL16 HSF2	6.73e-06	880	128	15	EFO_0007978
Disease	obstructive nephropathy (implicated_via_orthology)	EXOC5 MOCOS	1.87e-05	2	128	2	DOID:0070314 (implicated_via_orthology)
Disease	optic disc size measurement	TANC2 RPAP3 MACF1 FOXP1 LTBP1 HSF2 FILIP1L	3.28e-05	205	128	7	EFO_0004832
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	5.59e-05	3	128	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	5.59e-05	3	128	2	DOID:8545 (implicated_via_orthology)
Disease	Myoclonic-astatic epilepsy	CHD2 AP2M1	5.59e-05	3	128	2	cv:C0393702
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTBN1 SPTBN4	1.11e-04	4	128	2	DOID:0050882 (implicated_via_orthology)
Disease	Intellectual Disability	TANC2 HDAC4 ATL1 ZNF462 AP2M1 SUPT16H MACF1 ASCC3 WDR62	1.51e-04	447	128	9	C3714756
Disease	cognitive function measurement, self reported educational attainment	TANC2 EFL1 DENND4A IGF2BP1 FAM120A PKHD1 FOXP1 EEA1	1.66e-04	355	128	8	EFO_0004784, EFO_0008354
Disease	Epidermolysis Bullosa Simplex	ITGB4 DST	1.85e-04	5	128	2	C0079298
Disease	retinal degeneration (biomarker_via_orthology)	PHLDA1 PTPRC KCNJ10	2.41e-04	28	128	3	DOID:8466 (biomarker_via_orthology)
Disease	cortical thickness	INTU SPTBN1 SERP2 SERP1 PCDHB16 ZNF462 IGF2BP1 THBS3 MTMR3 PKHD1 MACF1 FOXP1 KLHL8 WNK2	3.48e-04	1113	128	14	EFO_0004840
Disease	Pulmonary Hypertension, Primary, 1, With Hereditary Hemorrhagic Telangiectasia	HDAC5 HDAC4	3.87e-04	7	128	2	C3714844
Disease	asphyxiating thoracic dystrophy (is_implicated_in)	INTU NEK1	3.87e-04	7	128	2	DOID:0050592 (is_implicated_in)
Disease	Pulmonary Hypertension, Primary, 1	HDAC5 HDAC4	3.87e-04	7	128	2	C4552070
Disease	PULMONARY HYPERTENSION, PRIMARY, DEXFENFLURAMINE-ASSOCIATED	HDAC5 HDAC4	3.87e-04	7	128	2	C1969342
Disease	Pulmonary Hypertension, Primary, Fenfluramine-Associated	HDAC5 HDAC4	3.87e-04	7	128	2	C1969343
Disease	cognitive function measurement	LVRN TANC2 EFL1 DENND4A ZFP57 CHD2 TMCC3 IGF2BP1 KMT2D FAM120A NFATC2IP PKHD1 FOXP1 LTBP1 EEA1 WNK2	4.90e-04	1434	128	16	EFO_0008354
Disease	mean platelet volume	HDAC5 IQGAP2 SPTA1 SPTBN1 PWWP2A OTP PTPRC GCC2 CKAP2L KCNQ1 LTBP1 KLHL8 ACAP2	5.04e-04	1020	128	13	EFO_0004584
Disease	Autistic behavior	ZNF462 AP2M1	5.14e-04	8	128	2	C0856975
Disease	hereditary spastic paraplegia (implicated_via_orthology)	ATL1 CAPN11 DDHD2	8.67e-04	43	128	3	DOID:2476 (implicated_via_orthology)
Disease	Myoclonic Astatic Epilepsy	CHD2 AP2M1	1.00e-03	11	128	2	C0393702
Disease	Long QT Syndrome	RYR2 KCNQ1	1.00e-03	11	128	2	C0023976
Disease	squamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma	TMCC3 PKHD1	1.41e-03	13	128	2	EFO_0000707, EFO_0004193, EFO_0007932
Disease	Short Rib-Polydactyly Syndrome	KIAA0586 NEK1	1.41e-03	13	128	2	C0036996
Disease	Saldino-Noonan Syndrome	KIAA0586 NEK1	1.64e-03	14	128	2	C0036069
Disease	Majewski Syndrome	KIAA0586 NEK1	1.64e-03	14	128	2	C0024507
Disease	anthranilic acid measurement	HDAC4 KCNQ1	2.15e-03	16	128	2	EFO_0010460
Disease	Idiopathic pulmonary arterial hypertension	HDAC5 HDAC4	2.15e-03	16	128	2	C3203102
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	NEK1 PKHD1	2.15e-03	16	128	2	DOID:0110861 (implicated_via_orthology)
Disease	response to acetylsalicylate	KIF9 KCNQ1	2.15e-03	16	128	2	GO_1903492
Disease	Familial primary pulmonary hypertension	HDAC5 HDAC4	2.43e-03	17	128	2	C0340543
Disease	cortical surface area change measurement, age at assessment	SPAG9 CFAP99	3.04e-03	19	128	2	EFO_0008007, EFO_0021503
Disease	hemoglobin measurement, mean corpuscular hemoglobin	DENND4A PTPRC	4.07e-03	22	128	2	EFO_0004509, EFO_0004527

Protein segments in the cluster

Peptide	Gene	Start	Entry
RAIIQNVDVQQKKAH	TDRD1	331	Q9BXT4
IHKIQQQKNIIFATG	ERI2	121	A8K979
LKQQHQQAVEQIAKA	CCDC89	236	Q8N998
QVSRANQHKEQQLGL	COPS7A	191	Q9UBW8
NEEIGKQQKVAVIHQ	EFL1	706	Q7Z2Z2
AKVAIESAVQQKQQH	ARID2	1566	Q68CP9
NALVKNAQVQRNKQH	ACAP2	136	Q15057
VHANLQTIKNENLKN	LVRN	961	Q6Q4G3
RLKAKGVGQHDNAQN	CAPN11	46	Q9UMQ6
QRIIGVINEHKKQNN	DHX29	96	Q7Z478
AQRVHTIGQKQKNDQ	ARHGEF39	191	Q8N4T4
TIGQKQKNDQHLRRV	ARHGEF39	196	Q8N4T4
KRHKSDNETNLQQQV	DENND4A	1011	Q7Z401
KQQFVQGRDNVHKEN	RAD51AP2	176	Q09MP3
SIQGNKQQLIKRHQE	RAD18	266	Q9NS91
QVKAHVQKEDGRVQA	SPAG9	631	O60271
SGKQQIAKENQQVAK	RANGRF	106	Q9HD47
VGHQQAGNVKQQEKS	MRNIP	86	Q6NTE8
VNTKNQAVKERAQGV	ARPC5L	66	Q9BPX5
QIIQGKHTKSQELQN	CFAP99	521	D6REC4
AHQLQQIAAKQKREQ	MAML1	396	Q92585
ISANGHQKQVEKSQN	PSTPIP1	161	O43586
QQKQRQKHFNRQIPA	KCNQ1	356	P51787
RQAKDKAAQQLQQEG	NKX2-4	246	Q9H2Z4
GQKEAHAQAGVQVKQ	HDAC4	546	P56524
HQTKEGENIRLNQVN	KCNJ10	221	P78508
KAVSKQANANRQKGQ	NEK1	511	Q96PY6
KQGQDHRLKSQTVQN	GMEB1	351	Q9Y692
NILKQDQHSQKITGV	DST	3236	Q03001
NSHKENIQGQLKVRT	FYCO1	1426	Q9BQS8
ILAQVKQQHQKGQSN	IGF2BP1	556	Q9NZI8
KQQHQKGQSNQAQAR	IGF2BP1	561	Q9NZI8
LNAQKGKNIQLHFQE	TMPRSS15	556	P98073
QTKVQQLQISVDQHG	KRT4	331	P19013
EVASLRQKHAQQQKV	HSF1	171	Q00613
ARNHITKGKRQQQHQ	KLHL8	11	Q9P2G9
TKGKRQQQHQQIKNR	KLHL8	16	Q9P2G9
QVHQKQQLQGVNVCG	LTBP1	156	Q14766
QKSGQDVSQAQRQIK	NCF1	281	P14598
QQHAGKQPKEQQQVA	FOXP1	161	Q9H334
LQGLNQKANKHIDQV	GUCA1C	46	O95843
THFKKAQENQQIGRV	DDHD2	251	O94830
VNRKKNVDQAIKNGQ	MACF1	1631	O94854
KQHVQINLNGRVSLN	METTL16	31	Q86W50
GIRQVITNHKQVQQQ	MED25	536	Q71SY5
IDQQTGQRNQHVFQK	MOCOS	816	Q96EN8
HVKVQKAGQQALRQI	GCN1	1551	Q92616
QGIKSQHQTKEEQSQ	AP2M1	136	Q96CW1
RQTAQQIVSHVQNKG	FAM120A	116	Q9NZB2
HLKKDIRRGVVNNQQ	KIF9	36	Q9HAQ2
VHKLQQTKFRQQPNA	ITGB4	861	P16144
HVTNQCKVNQTLKQV	PLEKHH2	1281	Q8IVE3
ILKHQSNQKTGVIVQ	INTU	141	Q9ULD6
IISQGNKQHLQLKAQ	PCDHB16	66	Q9NRJ7
KQLQQQREEKEQHGL	EEA1	396	Q15075
HQLDKTKQQHQEQQA	EEA1	481	Q15075
KVQELQKSNQVAFQH	EXOC5	81	O00471
QQAAALNAQHKQGKV	ESS2	266	Q96DF8
VKQAKGVRQQAVQLN	HEATR5B	811	Q9P2D3
KVSGNQHEELQNVRK	ATL1	241	Q8WXF7
QAQARAHRIGQKKQV	CHD2	896	O14647
ESKRLHNKENQHVQQ	FBXO5	111	Q9UKT4
GDHSVLQKKLNQQEN	FILIP1L	741	Q4L180
QHNREVQSLKEQHQK	GCC2	421	Q8IWJ2
KQKQLEAGEVVHQQF	MACC1	456	Q6ZN28
NNVNGNQVGHLKKEL	HLTF	101	Q14527
TRQHEVQLQKHLKQQ	HDAC5	106	Q9UQL6
RVAGELQSQVKNNQH	GOLGA8R	316	I6L899
THQNVIQFELGKQKN	RYR1	1556	P21817
QGQRNFSKAIQVAKQ	RYR2	3901	Q92736
LQPNKQKDQHAGARQ	MCMBP	176	Q9BTE3
SGHQQEVETLKKQVQ	MTMR3	1036	Q13615
GQQQGQQKQKRHRTR	OTP	96	Q5XKR4
AKHAQQQQVIRKIVQ	HSF2	166	Q03933
QIKNLERSGNQHKAE	ODF2	366	Q5BJF6
QQQQRRHQQGKVTVK	PPP1R14C	61	Q8TAE6
IKTGRHIVQKQQTDN	UTRN	1496	P46939
VDGKNQNESQKRNAV	PWWP2A	371	Q96N64
QHQFQQLKTGIVEKV	NUGGC	711	Q68CJ6
QQAGRIKQVFEKKNQ	TMCC3	106	Q9ULS5
QASQETRQKKHVTQN	RESF1	1316	Q9HCM1
GNINKVNRQAAVDHI	IQGAP2	296	Q13576
LVANKQQRETKNSHQ	SEMG1	201	P04279
KNLNQDQQHGRKANK	SEMG1	271	P04279
NEKHSKNITQRGNVA	SERP2	11	Q8N6R1
QQGVFKKSHAIQQAL	TANC2	981	Q9HCD6
LVVNKQQRETKNSHQ	SEMG2	201	Q02383
IQTEEKIHGKSQNQV	SEMG2	316	Q02383
IQTEEKIHGKSQNQV	SEMG2	436	Q02383
AQKTQDGQNIGIKHI	NETO2	26	Q8NC67
IKVNQVKDINLHGNV	PKHD1	3081	P08F94
QQLQLRVQGKEKHQT	NFATC2IP	346	Q8NCF5
SALKKQANHIVQQAQ	PHLDB2	766	Q86SQ0
QKGEQQIQKARKSNV	SUPT16H	496	Q9Y5B9
NQVEGQQKNLVHAIE	OSBPL10	246	Q9BXB5
NQQVKQAFKNVVHKV	OR6C3	291	Q9NZP0
SLRNKGNVQNIHKED	SNAPC1	321	Q16533
NGQNVVKVGHRQVVN	SHANK1	726	Q9Y566
KNQTLQKEIQGHQPR	SPTBN1	1526	Q01082
NINGITQHKQIVRND	SRRT	506	Q9BXP5
EQGNKENIHQIKQTV	CFAP20DC	196	Q6ZVT6
EIRQHFQQGVIKKNE	ASCC3	516	Q8N3C0
NRHPNIKQDQKSSQV	CKAP2L	346	Q8IYA6
KNRAQQLHKEQQKGV	COA7	211	Q96BR5
KTDIHQVAVQRNKNS	XIRP2	1786	A4UGR9
INKSQFIKQQRTHNI	ZNF615	186	Q8N8J6
SRLGKVQDVLHQVNQ	TAS1R3	251	Q7RTX0
KTVQDHSQIRDQQKG	ZCWPW1	231	Q9H0M4
KQIHGDTVQNQLVVQ	VPS35L	366	Q7Z3J2
DQSELKRHQKIHQNQ	ZFP57	186	Q9NU63
QKGKNNQTECFNHVR	SEMA4G	106	Q9NTN9
QQNKQQAISEKDRGN	RPAP3	276	Q9H6T3
EVNQVATGHQSKQKR	SAGE2P	76	A6NJ88
VVNLNVHGEKINKGQ	SAGE2P	256	A6NJ88
VGGKNIVDHTNEQQK	KIF3B	476	O15066
AVKSTRQKQQHLVQQ	PHLDA1	291	Q8WV24
NEKHSKNITQRGNVA	SERP1	11	Q9Y6X1
QGTTRKQQDFHEVNK	SCEL	21	O95171
RKTHQQQHQAAVRQQ	ZNF574	841	Q6ZN55
QQHVKLQKQIEDLQG	TTC3	341	P53804
TERGNGLQAVQQHIK	SPTBN4	1541	Q9H254
GLQAVQQHIKKNQGL	SPTBN4	1546	Q9H254
QQHIKKNQGLRREIQ	SPTBN4	1551	Q9H254
LQHGTQQQDLNKKER	TERF1	326	P54274
KEKTNRVNQHVQSLQ	TSKS	151	Q9UJT2
VQLFNAVQKHQKNVD	RRP15	171	Q9Y3B9
TKQKGTQLHEANQQL	SPTA1	676	P02549
QREDGKVHAVNLQQA	THBS3	101	P49746
HRQQQQHTNDKKRSG	WDR62	761	O43379
RGKQIDVKNNLQIHE	ZNF227	191	Q86WZ6
IKHNNVRAQPEGKNN	ZNF462	1681	Q96JM2
QVVKASGQNLNLRVH	TGM1	196	P22735
KTENNNHINLKVAGQ	SUMO4	11	Q6EEV6
ALHVQAQVNNSNNKK	WNK2	2141	Q9Y3S1
NVKNNQRVHQEGLSL	ZNF623	501	O75123
AQNGQVKKNNHQEDK	PTPRC	1231	P08575
QNQDVKQVEHKPSQS	KIAA0586	1431	Q9BVV6
VDTQRTKGQDNKVQN	YTHDF1	6	Q9BYJ9
QAFINQHTVERKGKQ	ZC3H8	181	Q8N5P1
KTHRQQEEQQRQKAQ	TRERF1	1106	Q96PN7
VQDLKHQIEGNVSKQ	GOLGB1	1756	Q14789
DNRAAHRINKVQKQA	KMT2D	2066	O14686
HRINKVQKQAESQIN	KMT2D	2071	O14686
AQEGLRSLQHQEKQK	KIAA1522	66	Q9P206