Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainLdl_recept_b

EGF LRP2 SORL1

6.36e-05141073PF00058
DomainLDLRB

EGF LRP2 SORL1

6.36e-05141073PS51120
DomainLY

EGF LRP2 SORL1

7.91e-05151073SM00135
DomainLDLR_classB_rpt

EGF LRP2 SORL1

7.91e-05151073IPR000033
DomainABC_transporter_CS

ABCF1 ABCC11 ABCF2 ABCB4

9.64e-05421074IPR017871
DomainABC_tran_Xtn

ABCF1 ABCF2

9.72e-0531072PF12848
DomainGPCR_2_brain_angio_inhib

ADGRB1 ADGRB3

9.72e-0531072IPR008077
DomainABC_tran_Xtn

ABCF1 ABCF2

9.72e-0531072IPR032781
DomainABC_tran

ABCF1 ABCC11 ABCF2 ABCB4

1.63e-04481074PF00005
DomainABC_TRANSPORTER_2

ABCF1 ABCC11 ABCF2 ABCB4

1.63e-04481074PS50893
DomainABC_TRANSPORTER_1

ABCF1 ABCC11 ABCF2 ABCB4

1.77e-04491074PS00211
DomainABC_transporter-like

ABCF1 ABCC11 ABCF2 ABCB4

1.91e-04501074IPR003439
DomainPKNOX/Meis_N

MEIS3 MEIS1

3.22e-0451072IPR032453
DomainGST_mu

GSTM1 GSTM2

3.22e-0451072IPR003081
DomainMeis_PKNOX_N

MEIS3 MEIS1

3.22e-0451072PF16493
DomainGST_C

AIMP2 GSTM1 GSTM2

4.32e-04261073IPR004046
DomainGST_C

AIMP2 GSTM1 GSTM2

4.32e-04261073PF00043
DomainGST_CTER

AIMP2 GSTM1 GSTM2

9.61e-04341073PS50405
DomainGlutathione-S-Trfase_C-like

AIMP2 GSTM1 GSTM2

1.44e-03391073IPR010987
Domain-

EGF LRP2 SORL1

1.44e-033910732.120.10.30
Domain-

AIMP2 GSTM1 GSTM2

1.44e-033910731.20.1050.10
DomainAAA+_ATPase

ABCF1 DYNC2H1 ABCC11 ABCF2 ABCB4

1.44e-031441075IPR003593
DomainAAA

ABCF1 DYNC2H1 ABCC11 ABCF2 ABCB4

1.44e-031441075SM00382
DomainLDLR_class-A_CS

NETO2 LRP2 SORL1

1.55e-03401073IPR023415
DomainGAIN_dom_N

ADGRB1 ADGRB3

1.73e-03111072IPR032471
DomainGAIN

ADGRB1 ADGRB3

1.73e-03111072PF16489
DomainLdl_recept_a

NETO2 LRP2 SORL1

2.18e-03451073PF00057
Domain-

NETO2 LRP2 SORL1

2.32e-034610734.10.400.10
Domain6-blade_b-propeller_TolB-like

EGF LRP2 SORL1

2.32e-03461073IPR011042
DomainLDLRA_1

NETO2 LRP2 SORL1

2.62e-03481073PS01209
DomainLDLRA_2

NETO2 LRP2 SORL1

2.78e-03491073PS50068
DomainLDrepeatLR_classA_rpt

NETO2 LRP2 SORL1

2.78e-03491073IPR002172
DomainLDLa

NETO2 LRP2 SORL1

2.78e-03491073SM00192
DomainHomeobox_KN

MEIS3 MEIS1

4.18e-03171072PF05920
DomainHomeobox_KN_domain

MEIS3 MEIS1

4.18e-03171072IPR008422
DomainTSP_1

ADGRB1 ADGRB3 SEMA5B

5.66e-03631073PF00090
Pubmed

Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.

TBXAS1 ABCF1 ABCF2 DDOST ABCB4 GSTM1 GSTM2 CHST2

1.96e-07193110819343046
Pubmed

Functional compensation of glutathione S-transferase M1 (GSTM1) null by another GST superfamily member, GSTM2.

GSTM1 GSTM2

9.91e-062110224048194
Pubmed

Endometriosis: a crosstalk between epidermal growth factor (EGF) gene polymorphism and telomerase activity?

TERT EGF

9.91e-062110221982438
Pubmed

Identification of residues in glutathione transferase capable of driving functional diversification in evolution. A novel approach to protein redesign.

GSTM1 GSTM2

9.91e-062110212486119
Pubmed

Quantitative assessment of the effect of glutathione S-transferase genes GSTM1 and GSTT1 on hepatocellular carcinoma risk.

GSTM1 GSTM2

9.91e-062110224399650
Pubmed

The redox state of cytochrome c modulates resistance to methotrexate in human MCF7 breast cancer cells.

GSTM1 GSTM2

9.91e-062110223675469
Pubmed

Transducer of Cdc42-dependent actin assembly promotes epidermal growth factor-induced cell motility and invasiveness.

FNBP1L EGF

9.91e-062110221062739
Pubmed

An inventory of the human ABC proteins.

ABCF1 ABCF2

9.91e-062110210581359
Pubmed

Amyloid-β-related genes SORL1 and ACE are genetically associated with risk for late-onset Alzheimer disease in the Chinese population.

ACE SORL1

9.91e-062110220625269
Pubmed

Human genes for glutathione S-transferases.

GSTM1 GSTM2

9.91e-06211026500576
Pubmed

Intracellular transactivation of epidermal growth factor receptor by α1A-adrenoceptor is mediated by phosphatidylinositol 3-kinase independently of activation of extracellular signal regulated kinases 1/2 and serine-threonine kinases in Chinese hamster ovary cells.

ADRA1A EGF

9.91e-062110223902938
Pubmed

Epidermal growth factor coordinately regulates the expression of prostaglandin G/H synthase and cytosolic phospholipase A2 genes in embryonic mouse cells.

EGF PLA2G1B

9.91e-06211028063822
Pubmed

Impact of domain interchange on conformational stability and equilibrium folding of chimeric class micro glutathione transferases.

GSTM1 GSTM2

9.91e-062110212192076
Pubmed

A multi-stage genome-wide association study of bladder cancer identifies multiple susceptibility loci.

TERT GSTM1 TMEM129

1.67e-0516110320972438
Pubmed

Do Polymorphisms of the TERT, GSTM1, and GSTT1 Genes Increase Laryngeal Cancer Susceptibility in Smokers of Romanian Descent?

TERT GSTM1

2.97e-053110236013573
Pubmed

Lack of association of genetic polymorphisms of angiotensin-converting enzyme gene I/D and glutathione-S-transferase enzyme T1 and M1 with retinopathy of prematures.

ACE GSTM1

2.97e-053110221038299
Pubmed

Acceleration of chronic myeloproliferation by enforced expression of Meis1 or Meis3 in Icsbp-deficient bone marrow cells.

MEIS3 MEIS1

2.97e-053110218223676
Pubmed

Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage.

GSTM1 GSTM2

2.97e-053110232574561
Pubmed

Characterization of the human class Mu glutathione S-transferase gene cluster and the GSTM1 deletion.

GSTM1 GSTM2

2.97e-05311029452477
Pubmed

EGF upregulates RFPL3 and hTERT via the MEK signaling pathway in non‑small cell lung cancer cells.

TERT EGF

2.97e-053110229749533
Pubmed

Cloning and characterization of BAI2 and BAI3, novel genes homologous to brain-specific angiogenesis inhibitor 1 (BAI1).

ADGRB1 ADGRB3

2.97e-05311029533023
Pubmed

Spinal astrocytes in superficial laminae gate brainstem descending control of mechanosensory hypersensitivity.

ITPR2 ADRA1A

2.97e-053110233020652
Pubmed

Expression of brain-specific angiogenesis inhibitor 3 (BAI3) in normal brain and implications for BAI3 in ischemia-induced brain angiogenesis and malignant glioma.

ADGRB1 ADGRB3

2.97e-053110215225653
Pubmed

Alternative mutations of a positively selected residue elicit gain or loss of functionalities in enzyme evolution.

GSTM1 GSTM2

2.97e-053110216549767
Pubmed

[Genetic study of predisposition to community-acquired pneumonia].

ACE GSTM1

2.97e-053110222312901
Pubmed

Genetic susceptibility, residential radon, and lung cancer in a radon prone area.

GSTM1 GSTM2

2.97e-053110224852519
Pubmed

Biosynthesis of 14,15-hepoxilins in human l1236 Hodgkin lymphoma cells and eosinophils.

GSTM1 GSTM2

2.97e-053110221046276
Pubmed

A common variant in the glutathione S transferase gene is associated with elevated markers of inflammation and lipid peroxidation in subjects with diabetes mellitus.

GSTM1 GSTM2

2.97e-053110216002077
Pubmed

DNA-repair and carcinogen-metabolising enzymes genetic polymorphisms as an independent risk factor for hepatocellular carcinoma in Caucasian liver-transplanted patients.

UGT1A7 GSTM1

2.97e-053110217870518
Pubmed

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.

MEIS3 MEIS1 PAX1

5.21e-0523110318691704
Pubmed

Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.

GSTM1 GSTM2

5.92e-05411028317488
Pubmed

[Association between genetic polymorphisms of metabolic enzymes and susceptibility of colorectal cancer].

UGT1A7 GSTM1

5.92e-054110216620591
Pubmed

Epidermal growth factor activates telomerase activity by direct binding of Ets-2 to hTERT promoter in lung cancer cells.

TERT EGF

5.92e-054110225680408
Pubmed

Three-amino-acid-loop-extension homeodomain factor Meis3 regulates cell survival via PDK1.

MEIS3 MEIS1

5.92e-054110221059917
Pubmed

[The association of risk of development of cardiomyopathies with polymorphic variants of genes of angiotensin converting enzyme, glutathione-S-transferase, interleukins 8 and 10].

ACE GSTM1

5.92e-054110225080784
Pubmed

The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor.

GSTM1 GSTM2

5.92e-054110222406107
Pubmed

Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript.

GSTM1 GSTM2

5.92e-05411028373352
Pubmed

c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells.

MEIS1 GSTM1

5.92e-054110216507773
Pubmed

Association of ACE, FABP2 and GST genes polymorphism with essential hypertension risk among a North Indian population.

ACE GSTM1

5.92e-054110225357227
Pubmed

Notch ligands are substrates for protein O-fucosyltransferase-1 and Fringe.

MFNG POFUT1

5.92e-054110212036964
Pubmed

Identification of a conserved family of Meis1-related homeobox genes.

MEIS3 MEIS1

5.92e-05411029049632
Pubmed

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death.

MEIS3 MEIS1 LNPK

7.59e-0526110326857994
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADGRB1 ADGRB3 EOMES SEMA5B

9.68e-0575110420637190
Pubmed

Association of the ACE, GSTM1, IL-6, NOS3, and CYP1A1 polymorphisms with susceptibility of mycoplasma pneumoniae pneumonia in Chinese children.

ACE GSTM1

9.85e-055110228403117
Pubmed

A cluster of thin tubular structures mediates transformation of the endoplasmic reticulum to autophagic isolation membrane.

ATG16L1 RB1CC1

9.85e-055110224591649
Pubmed

Diet-dependent obesity and hypercholesterolemia in the New Zealand obese mouse: identification of a quantitative trait locus for elevated serum cholesterol on the distal mouse chromosome 5.

COX6A1 PLA2G1B

9.85e-055110212727230
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP2 SORL1

9.85e-055110219047013
Pubmed

Glutathione S-transferase variants and hypertension.

GSTM1 GSTM2

9.85e-055110218551009
Pubmed

Genetic variants in GSTM3 gene within GSTM4-GSTM2-GSTM1-GSTM5-GSTM3 cluster influence breast cancer susceptibility depending on GSTM1.

GSTM1 GSTM2

9.85e-055110219856098
Pubmed

Pancreatic Tumor Progression Associated With CD133 Overexpression: Involvement of Increased TERT Expression and Epidermal Growth Factor Receptor-Dependent Akt Activation.

TERT EGF

9.85e-055110226646272
Pubmed

Multiple roles of mesenchymal beta-catenin during murine limb patterning.

COL12A1 MEIS1 PAX1

1.17e-0430110316495310
Pubmed

ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis.

MEIS3 MEIS1 LRP2

1.30e-0431110336445780
Pubmed

Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.

MEIS3 MEIS1

1.47e-046110222987645
Pubmed

Purification and characterization of eight glutathione S-transferase isoenzymes of hamster. Comparison of subunit composition of enzymes from liver, kidney, testis, pancreas and trachea.

GSTM1 GSTM2

1.47e-04611021530570
Pubmed

Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide.

ATG16L1 RB1CC1

1.47e-046110226929451
Pubmed

Association analysis of TNFR2, VDR, A2M, GSTT1, GSTM1, and ACE genes with rheumatoid arthritis in South Asians and Caucasians of East Midlands in the United Kingdom.

ACE GSTM1

1.47e-046110220401725
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ABCF1 AIMP2 BMS1 ABCF2 DDOST ITPR2 GSTM1 GSTM2 MRPS7 MYOF MAGED2 TFB2M SNTB2

1.74e-0412571101336526897
Pubmed

Regulation of Hyaluronan (HA) Metabolism Mediated by HYBID (Hyaluronan-binding Protein Involved in HA Depolymerization, KIAA1199) and HA Synthases in Growth Factor-stimulated Fibroblasts.

CEMIP EGF

2.06e-047110226518873
Pubmed

ILC1 Confer Early Host Protection at Initial Sites of Viral Infection.

EOMES ZBTB46

2.06e-047110229056343
Pubmed

Evidence for an association between haptoglobin and MnSOD (Val9Ala) gene polymorphisms in essential hypertension based on a Brazilian case-control study.

ACE GSTM1

2.06e-047110221053180
Pubmed

Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon.

MEIS3 MEIS1

2.06e-047110217178831
Pubmed

SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.

NECTIN2 SORL1

2.06e-047110223565137
Pubmed

Gene polymorphisms against DNA damage induced by hydrogen peroxide in leukocytes of healthy humans through comet assay: a quasi-experimental study.

ACE GSTM1

2.06e-047110220444272
Pubmed

Association of maternal histocompatibility at class II HLA loci with maternal microchimerism in the fetus.

ACE GSTM1

2.06e-047110215128924
Pubmed

Evaluation of gene polymorphisms in exercise-induced oxidative stress and damage.

ACE GSTM1

2.06e-047110220109103
Pubmed

PBX, MEIS, and IGF-I are potential mediators of retinoic acid-induced proximodistal limb reduction defects.

MEIS3 MEIS1

2.06e-047110212397630
Pubmed

A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development.

DYNC2H1 LRP2

2.06e-047110215314648
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

ABCF1 UBE3B CLSTN1 DDOST CEMIP SUPV3L1 CARD6 AP4B1 SORL1

2.29e-04650110938777146
Pubmed

Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.

SMDT1 CHDH COX6A1 MRPL54 MACROD1 PNPO MRPS7 SUPV3L1 TFB2M MALSU1 MOCS1 MUTYH

2.59e-0411361101234800366
Pubmed

Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy.

ATG16L1 RB1CC1

2.74e-048110230853401
Pubmed

Genetic polymorphisms in UDP-glucuronosyltransferases and glutathione S-transferases and colorectal cancer risk.

UGT1A7 GSTM1

2.74e-048110215319294
Pubmed

Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy.

ATG16L1 RB1CC1

2.74e-048110223262492
Pubmed

Genotype announcement in a genetic polymorphism study for health checkup examinees at Nagoya University Hospital.

ACE GSTM1

2.74e-048110215279067
Pubmed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

IFT140 ATG16L1 EOMES

2.79e-0440110329078390
Pubmed

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.

MEIS3 MEIS1

3.52e-049110212183364
Pubmed

[Analysis of genetic predisposition to pulmonary tuberculosis in native Russians].

GSTM1 SLC11A1

3.52e-049110220297661
Pubmed

Gene-load score of the renin-angiotensin-aldosterone system is associated with coronary heart disease in familial hypercholesterolaemia.

ACE ADRA1A

3.52e-049110218413308
Pubmed

Genetic variants of glutathione S-transferase as possible risk factors for hepatocellular carcinoma: a HuGE systematic review and meta-analysis.

GSTM1 GSTM2

3.52e-049110218065725
Pubmed

FIP200 regulates targeting of Atg16L1 to the isolation membrane.

ATG16L1 RB1CC1

3.52e-049110223392225
Pubmed

Genetic susceptibility to distinct bladder cancer subphenotypes.

AIMP2 RB1CC1 TERT GSTM1 EGF RPA4 MUTYH

3.96e-04421110719692168
Pubmed

Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.

ADGRB1 ADGRB3 FNBP1L NETO2 VANGL1

4.19e-04197110536604605
Pubmed

The human ATP-binding cassette (ABC) transporter superfamily.

ABCC11 ABCF2

4.39e-0410110211435397
Pubmed

Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes.

ATG16L1 RB1CC1

4.39e-0410110231959973
Pubmed

Homeostatic Control of Innate Lung Inflammation by Vici Syndrome Gene Epg5 and Additional Autophagy Genes Promotes Influenza Pathogenesis.

ATG16L1 RB1CC1

4.39e-0410110226764600
Pubmed

p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding.

ATG16L1 RB1CC1

4.39e-0410110221220506
Pubmed

Recruitment of the autophagic machinery to endosomes during infection is mediated by ubiquitin.

ATG16L1 RB1CC1

4.39e-0410110224100292
Pubmed

Identification of a new family of Pbx-related homeobox genes.

MEIS3 MEIS1

4.39e-041011028950991
Pubmed

Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.

MEIS3 MEIS1

5.35e-0411110218787068
Pubmed

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

ACE LRP2

5.35e-0411110222999937
Pubmed

Autophagy Genes Enhance Murine Gammaherpesvirus 68 Reactivation from Latency by Preventing Virus-Induced Systemic Inflammation.

ATG16L1 RB1CC1

5.35e-0411110226764599
Pubmed

Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.

PDE4D SEMA5B

5.35e-0411110221642993
Pubmed

Frequencies of polymorphisms in cytokines, neurotransmitters and adrenergic receptors in patients with complex regional pain syndrome type I after distal radial fracture.

ACE ADRA1A

5.35e-0411110220173430
Pubmed

Calsyntenins function as synaptogenic adhesion molecules in concert with neurexins.

ADGRB1 ADGRB3 CLSTN1

6.08e-0452110324613359
Pubmed

WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.

ATG16L1 RB1CC1

6.41e-0412110224954904
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

FNBP1L BNIP2 VANGL1 SNTB2

6.84e-04125110429467281
Pubmed

Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.

CASZ1 PNPO SUPV3L1

7.16e-0455110336758106
Pubmed

Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.

SMDT1 CHDH COX6A1 MRPL54 ABCF2 MRPS7 CPT1C SUPV3L1 TFB2M MUTYH

7.27e-049261101020877624
Pubmed

CbGRiTS: cerebellar gene regulation in time and space.

EOMES MFNG

7.56e-0413110225446528
Pubmed

WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy.

ATG16L1 RB1CC1

7.56e-0413110228561066
Pubmed

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.

MEIS3 MEIS1

7.56e-0413110216847320
GeneFamilyATP binding cassette subfamily F

ABCF1 ABCF2

4.17e-053682810
GeneFamilyAdhesion G protein-coupled receptors, subfamily B

ADGRB1 ADGRB3

4.17e-053682912
CoexpressionGSE10500_ARTHRITIC_SYNOVIAL_FLUID_VS_HEALTHY_MACROPHAGE_DN

TBC1D19 SZT2 ADGRB3 ITPR2 POFUT1 TFB2M DDHD2

2.55e-061451097M359
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

IFT140 SZT2 SUSD3 FNBP1L GSTM2 SORL1

3.12e-061621106810881210e015c788814e4fe8d7a24c929cf2621
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

COL12A1 ADGRB3 MEIS3 MYOF SEMA5B CHST2

6.90e-061861106cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCellNS-moderate-d_0-4-Myeloid-Non-resident_Macrophage|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TBXAS1 TTYH2 ITPR2 CEMIP SLC11A1 CNGB1

7.12e-061871106fcc32dbc9c5ae6176f154715a3e73aa32d78ad64
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNBP1L CLSTN1 MEIS1 MFNG VANGL1 CHST2

7.57e-06189110609dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCelldroplet-Liver-hepatocytes-3m-Epithelial-duct_epithelial_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE4D CASZ1 MYOF VANGL1 MPZL2 TMPRSS11A

7.80e-0619011065b3f773380aef4773b70f0dbd74992d28e6586c6
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NAALAD2 TTYH2 MEIS1 MAGED2 SEMA5B CHST2

7.80e-06190110684fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

COL12A1 ADGRB3 MEIS3 MYOF ADRA1A SEMA5B

8.03e-06191110678c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 GSTM1 MYOF NECTIN2 MPZL2 SORL1

8.53e-061931106268925bfe85fb94a93a4ff8fe078d692df888140
ToppCelldroplet-Bladder-nan-3m-Epithelial-bladder_urothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 GSTM1 MYOF NECTIN2 MPZL2 SORL1

8.53e-061931106ee91a796d0f6d4cee7a93a525689e716fdceeda5
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

ADGRB3 ST8SIA1 MEIS1 CEMIP ADRA1A MOCS1

8.53e-061931106ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DAGLB ABCB4 ITPR2 GSTM2 SLC11A1 SORL1

9.58e-061971106b597c292fc1cb381a4325fed15a32966c38def28
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBXAS1 ITPR2 LGALS9 MYOF SLC11A1 SORL1

1.01e-051991106e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TBC1D19 NAALAD2 DYNC2H1 WDR54 MALSU1

3.23e-051471105c0f62ed3312a33921476e89844486e09326485b7
ToppCell390C-Lymphocytic-ILC|390C / Donor, Lineage, Cell class and subclass (all cells)

ST8SIA1 RB1CC1 F2RL1 ABCB4 MAGED2

5.44e-051641105b0fc63b72162b5cc4d1e0a271a12f3d3ab29398f
ToppCellcontrol-Myeloid-pDC|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

SZT2 CASZ1 PNPO GSTM1 SUPV3L1

6.10e-051681105affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAALAD2 TTYH2 OLFM3 MAGED2 SEMA5B

6.45e-0517011051f994b690e881106a5d54b3080ccce6260bc3ac5
ToppCellfacs|World / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLSTN1 LGALS9 GSTM1 GSTM2 DDHD2

6.63e-051711105bb71e816dde44fda6af0ad98d979be9f8740fda6
ToppCellfacs|World / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLSTN1 LGALS9 GSTM1 GSTM2 DDHD2

6.63e-0517111055bcb96ed7fc15548f2dc9cf47482f890640cb39c
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

TBXAS1 GLB1L3 FAM120AOS MFNG ZNF44

6.82e-051721105c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 ST8SIA1 ZBTB46 SEMA5B CHST2

7.40e-05175110512f5fd83c7710fc0c77406f765d9cbd133433b8b
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADGRB1 SUSD3 ST8SIA1 ACE MYOF

7.40e-0517511056374ab186d7ccf7f6dfb858267edba8962789e15
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 COL12A1 ADGRB3 MEIS1 ZBTB46

8.45e-051801105280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 COL12A1 ADGRB3 MEIS1 ZBTB46

8.45e-051801105fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

COL12A1 ADGRB3 MEIS3 F2RL1 MEIS1

8.90e-051821105ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 ADGRB3 ST8SIA1 MEIS1 ZBTB46

1.01e-04187110515d6e158562d7d85af3ceaf955439b379c8fce81
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 ADGRB3 ST8SIA1 MEIS1 ZBTB46

1.01e-041871105f62074b631fd45ad299c69d71b09267b04d656ee
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COL12A1 ADGRB3 ST8SIA1 MEIS1 ZBTB46

1.04e-04188110532f22a4d8cb98fd8b8fa0fbf28ef9266d711d081
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE4D DYNC2H1 CASZ1 MYOF EGF

1.06e-041891105e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE4D ADGRB3 ST8SIA1 MEIS1 MYOF

1.06e-0418911052a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCelldroplet-Trachea-3m-Epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

F2RL1 CASZ1 GSTM2 NECTIN2 MPZL2

1.09e-0419011050114cf48612d78c3ada4d8a05850501fef6892c5
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

F2RL1 CASZ1 GSTM2 NECTIN2 MPZL2

1.09e-04190110501e7747547ea1f3049a11a1717565ba71dd52bdc
ToppCelldroplet-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL1 CASZ1 GSTM2 NECTIN2 MPZL2

1.09e-041901105e647f9a2dcf7f2dffef53c45bbe171416518fd59
ToppCelldroplet-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL1 CASZ1 GSTM2 NECTIN2 MPZL2

1.09e-041901105434de72dde09644efbddcaa643a4a3eaf5f643bf
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

MEIS1 GSTM2 MAGED2 CHST2 SLC7A10

1.12e-0419111053379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAALAD2 TTYH2 MAGED2 SEMA5B CHST2

1.14e-041921105430ef714bf2544d32f3fd96a55af010f79aa9be0
ToppCellfacs-Marrow-KLS-3m-Hematologic-MPP_Fraction_A_+_HSC|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBXAS1 FNBP1L MEIS1 MFNG MAGED2

1.14e-041921105959c28d28397bc0b9d3970d1fe3293d2750e63d4
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SUSD3 ITPR2 LGALS9 MYOF SORL1

1.17e-041931105697518bab1338dc441b2d93b410d957e692f20e6
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAALAD2 ADGRB3 ST8SIA1 MEIS1 ADRA1A

1.17e-041931105fb28717fadd06c3840636d25409ce80c9254bd34
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 MEIS1 GSTM1 GSTM2 MAGED2

1.20e-041941105da926441053b499cb5107ccb116fb1b3844d82b7
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAALAD2 ADGRB3 ST8SIA1 MEIS1 ADRA1A

1.20e-04194110560622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCelldroplet-Bladder-Unstain-18m-Endothelial-endothelial_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE MFNG ADRA1A SLC11A1 SEMA5B

1.20e-0419411059d7cbbcf995274019ca10be0562f114513ec197a
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 MEIS1 GSTM1 GSTM2 MAGED2

1.20e-04194110554a7f693966b5c02f6b248950ddb5fa32af3ae67
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 MEIS1 GSTM1 GSTM2 MAGED2

1.20e-041941105f34b3bbdebf56f66ff499e390e5515a4a4093f90
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 ADGRB3 ST8SIA1 MEIS1 CHST2

1.20e-041941105a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDE4D ADGRB3 MEIS1 CHST2

1.23e-0419511051cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDE4D ADGRB3 MEIS1 CHST2

1.23e-0419511050e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR2 MAGED2 NECTIN2 PLA2G1B MPZL2

1.26e-0419611057d5eaed189aa6116f3799be010139fb675ec65e0
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDE4D ADGRB3 MEIS1 CHST2

1.26e-0419611051450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellcontrol-Non-classical_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TBXAS1 LGALS9 MYOF SLC11A1 CHST2

1.26e-0419611051d71a5be652dd3281aba4f984f6ef84c993c5f63
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR2 MAGED2 NECTIN2 PLA2G1B MPZL2

1.26e-041961105dbf154b3d166ffd07be717dac8d8a3350ac63e16
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDE4D ADGRB3 MEIS1 CHST2

1.29e-04197110531a1852911bda38543916585fda34255fd62a134
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL12A1 FNBP1L F2RL1 MYOF MAGED2

1.29e-041971105d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCelldroplet-Bladder-BLADDER-1m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 COL12A1 LGALS9 MAGED2 CHST2

1.29e-04197110586145bc1e585b4ae136e755cafd6579da2abfa65
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL12A1 FNBP1L F2RL1 MYOF MAGED2

1.29e-04197110580b05c8ad9c1edc5dea3236079372475431343fe
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBXAS1 SUSD3 LGALS9 SLC11A1 SORL1

1.29e-041971105769a4203c014b34d16d4d76d3caf07ddb2c41abc
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 PDE4D ADGRB3 MEIS1 CHST2

1.32e-04198110517dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TBXAS1 SUSD3 LGALS9 SLC11A1 SORL1

1.32e-041981105979c391a3b7130e4f91d76a9eb8079fb0f445c4c
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CLSTN1 CASZ1 MEIS1 MYOF MPZL2

1.38e-04200110597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCelldistal-Endothelial-Capillary_Aerocyte-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACE MEIS1 MAGED2 NETO2 CHST2

1.38e-0420011050656906d16b0df19c0511965b5d18e9eab3cb168
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW08-Mesenchymal|GW08 / Sample Type, Dataset, Time_group, and Cell type.

GSTM2 MYOF TSR3 CABIN1 CNGB1

1.38e-042001105e5b7d9622b96bb20c81ac76b4e60e8b44fa9cca1
ToppCellwk_08-11-Mesenchymal-Fibroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 MEIS1 GSTM2 MAGED2 CHST2

1.38e-042001105482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCelldistal-1-Endothelial-Capillary_Aerocyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ACE MEIS1 MAGED2 NETO2 CHST2

1.38e-04200110559bacd738433cec6d05624a25fdfc087fb3ca3b5
ToppCellControl-Control-Myeloid-CD16+_Monocyte|Control / Disease, condition lineage and cell class

TBXAS1 LGALS9 MYOF SLC11A1 CHST2

1.38e-0420011058dd124a5aca897652ea68efbfc5a167b4cf31aef
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CLSTN1 CASZ1 MEIS1 MYOF MPZL2

1.38e-042001105ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellwk_15-18-Mesenchymal-Fibroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

NAALAD2 MEIS1 GSTM2 MAGED2 CHST2

1.38e-0420011054f624c3c57d1a84baa86d0830cb1b83ae110bf67
ToppCellBronchus_Control_(B.)-Immune-TX-DCs|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

TBXAS1 TTYH2 SUSD3 ITPR2 LGALS9

1.38e-042001105e0beacb88bbdc353a3e883171613027feafcf1ef
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADGRB3 FNBP1L CASZ1 MEIS1 EGF

1.38e-04200110585c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRB1 PLA2G1B CHST2 MPZL2

1.39e-0410611043aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
Diseasemonocyte count

DAGLB TBXAS1 SZT2 U2SURP UBE3B MACROD1 CLSTN1 F2RL1 CASZ1 MEIS1 GSTM1 GSTM2 EGF CHST2 CABIN1 SLC7A10 SORL1

3.12e-06132010317EFO_0005091
Diseasemetabolite measurement

MRI1 GLB1L3 UGT1A7 ACE ITPR2 GSTM2 MYOF OLFM3 CABIN1 C4orf33 SORL1

4.31e-0656010311EFO_0004725
Diseaselevel of glutathione S-transferase mu 1 in blood serum

GSTM1 GSTM2

1.21e-0521032OBA_2041806
DiseaseMalignant neoplasm of breast

TBXAS1 DYNC2H1 SUSD3 RB1CC1 TERT MEIS1 EOMES MRPS7 ADRA1A EGF MAGED2 SEMA5B NECTIN2 SORL1

2.22e-05107410314C0006142
DiseaseDisease Exacerbation

ABCF1 ABCC11 ABCF2 TERT ABCB4 EGF

2.55e-051651036C0235874
DiseaseBrugada syndrome (implicated_via_orthology)

GSTM1 GSTM2

1.20e-0451032DOID:0050451 (implicated_via_orthology)
DiseaseUterine leiomyoma, breast carcinoma

TERT GSTM2 ZBTB46

1.90e-04321033EFO_0000305, HP_0000131
DiseaseDrug Allergy

TBXAS1 ACE GSTM1

2.49e-04351033C0013182
Diseasegallbladder cancer (is_marker_for)

GSTM1 EGF

2.51e-0471032DOID:3121 (is_marker_for)
DiseaseKidney Diseases

ACE TERT EGF LRP2

2.61e-04881034C0022658
DiseaseSchizophrenia

PDE4D RTN4R RB1CC1 ACE PNPO GSTM1 GSTM2 ADRA1A LRP2 PLA2G1B SLC7A10

2.64e-0488310311C0036341
DiseaseProstatic Neoplasms

TBXAS1 PDE4D ACE TERT CASZ1 GSTM1 EGF NECTIN2 LRP2

3.12e-046161039C0033578
DiseaseMalignant neoplasm of prostate

TBXAS1 PDE4D ACE TERT CASZ1 GSTM1 EGF NECTIN2 LRP2

3.12e-046161039C0376358
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS3 MEIS1

3.33e-0481032DOID:0050425 (implicated_via_orthology)
DiseaseMental deterioration

NECTIN2 SORL1

4.28e-0491032C0234985
DiseaseMild cognitive disorder

NECTIN2 SORL1

4.28e-0491032C1270972
Diseasecholestasis (implicated_via_orthology)

ABCB4 GSTM1

4.28e-0491032DOID:13580 (implicated_via_orthology)
Diseaseliver cirrhosis (is_implicated_in)

ACE ABCB4 GSTM1

4.61e-04431033DOID:5082 (is_implicated_in)
DiseaseJeune thoracic dystrophy

IFT140 DYNC2H1

6.50e-04111032C0265275
DiseaseX-21796 measurement

UGT1A7 GSTM2

6.50e-04111032EFO_0800825
Diseaseapolipoprotein B to apolipoprotein A1 ratio

GSTM1 GSTM2 NECTIN2

6.77e-04491033EFO_0021897
DiseaseShort Rib-Polydactyly Syndrome

IFT140 DYNC2H1

9.18e-04131032C0036996
Diseaseretinol dehydrogenase 16 measurement

UGT1A7 NECTIN2

9.18e-04131032EFO_0802007
DiseaseCalcium channel blocker use measurement

TBC1D19 CHDH ACE CASZ1 ZBTB46

9.23e-042131035EFO_0009930
Diseasefree cholesterol to total lipids in large HDL percentage

GSTM1 GSTM2 NECTIN2

1.00e-03561033EFO_0022279
DiseaseImpaired cognition

NECTIN2 SORL1

1.07e-03141032C0338656
DiseaseSaldino-Noonan Syndrome

IFT140 DYNC2H1

1.07e-03141032C0036069
DiseaseMajewski Syndrome

IFT140 DYNC2H1

1.07e-03141032C0024507
Diseaselow density lipoprotein particle size measurement

MACROD1 GSTM1 GSTM2

1.11e-03581033EFO_0008593
Diseaseallergic disease (is_implicated_in)

ACE GSTM1

1.23e-03151032DOID:1205 (is_implicated_in)
DiseaseGlobal developmental delay

SZT2 PNPO TAF1 LNPK

1.24e-031331034C0557874
Diseaseuric acid measurement

NAALAD2 DYNC2H1 MACROD1 FNBP1L CEMIP MYOF LRP2 MPZL2

1.36e-036101038EFO_0004761
Diseasesarcoidosis (is_implicated_in)

ACE SLC11A1

1.40e-03161032DOID:11335 (is_implicated_in)
Diseasechronic obstructive pulmonary disease (is_implicated_in)

ACE F2RL1 GSTM1

1.41e-03631033DOID:3083 (is_implicated_in)
DiseaseBladder Neoplasm

TERT GSTM1 EOMES NECTIN2

1.49e-031401034C0005695
DiseaseMalignant neoplasm of urinary bladder

TERT GSTM1 EOMES NECTIN2

1.53e-031411034C0005684
Diseaseulcerative colitis (is_implicated_in)

GSTM1 SLC11A1

1.59e-03171032DOID:8577 (is_implicated_in)
Diseaseglomerulonephritis (implicated_via_orthology)

TBXAS1 ACE

1.59e-03171032DOID:2921 (implicated_via_orthology)
Diseaselymphocyte count

DAGLB PDE4D MACROD1 CLSTN1 CASZ1 ITPR2 EOMES EGF SUPV3L1 NECTIN2 CHST2 DDHD2 SLC7A10

1.76e-03146410313EFO_0004587
Diseaseplatelet crit

U2SURP SUSD3 TERT ITPR2 EOMES EGF NECTIN2 CHST2 SLC7A10 SORL1

1.84e-0395210310EFO_0007985
DiseaseNon-alcoholic Fatty Liver Disease

ACE ABCB4 GSTM1

1.91e-03701033C0400966
DiseaseNonalcoholic Steatohepatitis

ACE ABCB4 GSTM1

1.91e-03701033C3241937
Diseaseinflammatory bowel disease (is_implicated_in)

GSTM1 SLC11A1

1.99e-03191032DOID:0050589 (is_implicated_in)
Diseaseleukemia (implicated_via_orthology)

MEIS3 MEIS1

1.99e-03191032DOID:1240 (implicated_via_orthology)
Diseasestomach cancer (is_implicated_in)

ACE GSTM1 MUTYH

2.07e-03721033DOID:10534 (is_implicated_in)
Diseasemultiple sclerosis (is_implicated_in)

GSTM1 SLC11A1 NECTIN2

2.15e-03731033DOID:2377 (is_implicated_in)
Diseaseapolipoprotein B measurement

UGT1A7 MACROD1 CASZ1 ABCB4 GSTM1 GSTM2 MYOF NECTIN2

2.28e-036631038EFO_0004615
Diseaseurinary bladder cancer (is_implicated_in)

TERT GSTM1 SLC11A1

2.41e-03761033DOID:11054 (is_implicated_in)
Diseasesaturated fatty acids to total fatty acids percentage

GSTM1 GSTM2

2.43e-03211032EFO_0022305
DiseaseMammary Carcinoma, Human

DYNC2H1 RB1CC1 TERT MEIS1 MRPS7 EGF NECTIN2

2.47e-035251037C4704874
DiseaseMammary Neoplasms, Human

DYNC2H1 RB1CC1 TERT MEIS1 MRPS7 EGF NECTIN2

2.47e-035251037C1257931
DiseaseMammary Neoplasms

DYNC2H1 RB1CC1 TERT MEIS1 MRPS7 EGF NECTIN2

2.53e-035271037C1458155
Diseasesex interaction measurement, bilirubin measurement

COL12A1 F2RL1

2.66e-03221032EFO_0004570, EFO_0008343
Diseasenephrosis (biomarker_via_orthology)

ACE LRP2

2.66e-03221032DOID:2527 (biomarker_via_orthology)
DiseaseBreast Carcinoma

DYNC2H1 RB1CC1 TERT MEIS1 MRPS7 EGF NECTIN2

2.83e-035381037C0678222
Diseasesphingomyelin 24:1 measurement

PDE4D CCDC70

2.91e-03231032EFO_0010398
Diseaseglioblastoma (is_implicated_in)

ADGRB1 EGF

3.17e-03241032DOID:3068 (is_implicated_in)
Diseasesystemic scleroderma (is_implicated_in)

GSTM1 SLC11A1

3.17e-03241032DOID:418 (is_implicated_in)
Diseasetype 1 diabetes mellitus (is_implicated_in)

ACE GSTM1 SLC11A1

3.32e-03851033DOID:9744 (is_implicated_in)
DiseaseTEMPS-A questionnaire

DYNC2H1 ADGRB3

3.44e-03251032EFO_0004783

Protein segments in the cluster

PeptideGeneStartEntry
GTWALFFRKRRADMP

VANGL1

166

Q8TAA9
SFSKMRTGWRGAIPL

LINC00114

21

Q6XXX2
YQRKMAAGLPWTSRT

EOMES

581

O95936
NRPTQKFSGGWRMRV

ABCF1

446

Q8NE71
KFSGGWRMRVSLARA

ABCF1

451

Q8NE71
LKDFSGGWRMRVALA

ABCF2

226

Q9UG63
KRFCLVPSMEGVRWA

AASDHPPT

6

Q9NRN7
VWKQELPLSFRMSRG

C4orf33

96

Q8N1A6
RLATAMKLGFSRPWP

ACE

1166

P12821
RWATRIQDMFTGGKL

SLC7A10

181

Q9NS82
ATDISFPMKGWRATG

ADGRB1

781

O14514
SMVWKRTPAGDLAFN

ADGRB3

521

O60242
ISMPTASGAKKRFWI

CASZ1

1391

Q86V15
MSSGLRAADFPRWKR

ATG16L1

1

Q676U5
EWKFFSSMPRGSARI

ADRA1A

396

P35348
IQTIAMSRAGSRPWK

AP4B1

666

Q9Y6B7
MSRAGSRPWKAYLSA

AP4B1

671

Q9Y6B7
MPKLQGFEFWSRTLR

DUS1L

1

Q6P1R4
MASGAARWLVLAPVR

SMDT1

1

Q9H4I9
KVSRWMGLACFRSLA

CCDC70

16

Q6NSX1
FTISVWMRHGPFGRK

CLSTN1

386

O94985
RGSSKWMARTGVFLA

DGAT1

396

O75907
GRFITVMKFRPLTWQ

BMS1

236

Q14692
MASKGRYVSRGPWTR

CEMIP

1291

Q8WUJ3
PMRGTSVGWLKLRSA

CHDH

426

Q8NE62
MGWRLSARSGPRFKE

ITPR2

1576

Q14571
RGIFPKVATNIMRAW

MEIS1

276

O00470
ASGASRRPWVLGKVM

RB1CC1

1546

Q8TDY2
EIKASPQMWAARFRG

NTM-AS1

16

Q6ZSK4
FLWGPRAHAEIRKMS

MAGEA10

296

P43363
ASMARRASRGPIAFW

MAGED2

211

Q9UNF1
MSFFERLRSATWKPV

GLB1L3

551

Q8NCI6
RKMPFVRGQSFSVWI

LGALS9

296

O00182
MSWPSSFQGLRRFDV

PDE4D

141

Q08499
ATMNTKRREPWLFGE

GANC

646

Q8TET4
SRFLPRPVFTKMAVW

GSTM2

201

P28161
WGKYDAALRTMIPFR

ABCC11

61

Q96J66
LGSLRMAWKSFTRAP

DDHD2

591

O94830
RGIFPKVATNIMRAW

MEIS3

266

Q99687
RKLWAFTGPGFLMSI

SLC11A1

56

P49279
PMSGRFKDRVSWDGN

MPZL2

86

O60487
FRPAKIMRAWSDGSH

LRP2

846

P98164
MTCWLRGVTATFGRP

PNPO

1

Q9NVS9
RMWKTLTFFVALPGV

COX6A1

36

P12074
RKMEPSTAARAWALF

DDOST

16

P39656
RPRMSFSSQVATLWK

MOCS1

411

Q9NZB8
TRMAPNGWKSRLFRH

ABCB4

651

P21439
PSNGMALWVFLFRTK

F2RL1

91

P55085
MKFTLGLGSRAWRVS

PAX1

1

P15863
GAMSSPTKTWLALVR

CPT1C

141

Q8TCG5
SGAGKSTLWRMLRAA

DYNC2H1

1981

Q8NCM8
SLKASWVMGRPFGSE

CARD6

746

Q9BX69
PNRFDSWAGMALARA

CABIN1

1086

Q9Y6J0
SFRSLKRGWSVKMGP

FNBP1L

376

Q5T0N5
TSAPGMVRGYRVSWK

COL12A1

926

Q99715
RGIAVHPMAKRLFWT

EGF

601

P01133
MPGMVLFGRRWAIAS

DAGLB

1

Q8NCG7
AGRKTLRSCMGLEWF

C17orf80

451

Q9BSJ5
STLEMFAARWRSKAP

BPIFB6

336

Q8NFQ5
LNGATTRRKMPSLGW

BNIP2

211

Q12982
RTAGVRTWAPLAMAA

MACROD1

71

Q9BQ69
LAPLMWRRAVSSVAG

MALSU1

11

Q96EH3
GWRESLKMRVSKPFG

FMR1NB

56

Q8N0W7
GRVAMWRKVPDFLGS

IFT140

346

Q96RY7
TRFGAWMTDPLASEK

OLFM3

236

Q96PB7
APGAMLASWARIAAR

DPPA2

181

Q7Z7J5
KLALKMAPWASGSRF

MFNG

206

O00587
MGAAAWARPLSVSFL

POFUT1

1

Q9H488
MKRASAGGSRLLAWV

RTN4R

1

Q9BZR6
PSKAGRRSFWDMLSK

SZT2

2436

Q5T011
MAAPAVKVARGWSGL

MRPS7

1

Q9Y2R9
MRWAAATLRGKARPR

SUSD3

1

Q96L08
LWVSFGRKPMRAAQF

SORL1

326

Q92673
PWNTTRAFIAAMKGK

TAF1

931

P21675
PSFSIAEHWRRMKGA

OR5AU1

41

Q8NGC0
SRFLPRPVFSKMAVW

GSTM1

201

P09488
ARIPGLTLTWKRMSA

FAM120AOS

101

Q5T036
TSRGAMAVLAWKFPR

ST8SIA1

11

Q92185
WKFPRTRLPMGASAL

ST8SIA1

21

Q92185
VVGMFPSRGEKRALW

TFB2M

191

Q9H5Q4
AWEAIRAMKVRGAPA

MRI1

36

Q9BV20
LWAIMRKPRAAVGSG

MUTYH

11

Q9UIF7
SPPLIRSTGRFMWIK

NETO2

126

Q8NC67
DSGISPRAVWQFRKM

PLA2G1B

16

P04054
GWPRLTAVMKLRVTS

OR6T1

306

Q8NGN1
MSFSRALLWARLPAG

SUPV3L1

1

Q8IYB8
RFGPLASVKIMWPRT

U2SURP

296

O15042
FRSMNSALGKSPWLA

AIMP2

256

Q13155
WPASPLGMKVFRRKA

CHST2

41

Q9Y4C5
NSPSRRVLTWLMKGV

CNGB1

96

Q14028
RWEEVRGALMSAFSP

TBXAS1

131

P24557
DMTAKPIEARQWFGR

RPA4

96

Q13156
MATKRLFGATRTWAG

MRPL54

1

Q6P161
LAFSTMICAGPRAWK

TTYH2

401

Q9BSA4
SQRWFFSGRPLTDKM

UBTD2

191

Q8WUN7
FLGALPSKMRTWVQS

ZSCAN1

86

Q8NBB4
FLFVSGLSSMRRGLW

SCAI

486

Q8N9R8
WTTFMKARLNCSRPG

SEMA5B

336

Q9P283
SGFRSIIKPEWIRMF

UBE3B

901

Q7Z3V4
TCMGKWFASRQDPLR

TMEM129

321

A0AVI4
GAGPAMAVWTRATKA

SNTB2

11

Q13425
IGAQPLRISFKWMVR

TBC1D19

436

Q8N5T2
GKAFFWPSLLRMHER

ZNF44

251

P15621
KMSVRDCAWLRRSPG

TERT

511

O14746
MVFADARWTAPLRSA

UGT1A7

91

Q9HAW7
VMAGRSISPWLARRT

ZBTB46

161

Q86UZ6
VGFGTRSRNLKPWMI

TMPRSS11A

6

Q6ZMR5
WARLDETPFGKMRGS

TSR3

126

Q9UJK0
MFRWERSIPLRGSAA

WDR54

1

Q9H977
LTFPWMDSGRRFAKD

TLX2

116

O43763
MGGLFSRWRTKPSTV

LNPK

1

Q9C0E8
SFGKLMSKGWRPRRT

NAALAD2

391

Q9Y3Q0
MSKGWRPRRTIIFAS

NAALAD2

396

Q9Y3Q0
WRRKMAPSETHGAAA

MYOF

1076

Q9NZM1
PKGSVRGMTWLRVIA

NECTIN2

146

Q92692