Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC25A24 SLC2A10 CACNA1E SLC36A1 SLC16A6 MRS2 SLC15A4 ATRAID COX4I1 SLC22A2 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC35F1 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC2A1 SLC44A3 SLC5A1 ITPR1 SLC5A4

3.26e-1211808125GO:0022857
GeneOntologyMolecularFunctiontransporter activity

SLC25A24 SLC2A10 CACNA1E SLC36A1 SLC16A6 MRS2 SLC15A4 ATRAID COX4I1 SLC22A2 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC35F1 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC2A1 SLC44A3 SLC5A1 ITPR1 SLC5A4

2.22e-1112898125GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC25A24 SLC2A10 CACNA1E SLC36A1 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC5A1 ITPR1 SLC5A4

1.35e-107588119GO:0015318
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC2A10 CACNA1E SLC36A1 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

4.48e-106278117GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC2A10 CACNA1E SLC36A1 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

1.07e-096648117GO:0008324
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC2A10 SLC36A1 SLC15A4 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC5A1 SLC5A4

1.27e-09119819GO:0015294
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC2A10 CACNA1E SLC36A1 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC5A1 ITPR1 SLC5A4

2.17e-097938118GO:0015075
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC25A24 SLC2A10 SLC36A1 SLC15A4 SLC9A7 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 SLC5A4

2.56e-092968112GO:0015291
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC2A10 SLC36A1 SLC15A4 COX4I1 SLC9A7 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 SLC5A4

3.09e-093018112GO:0022853
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC25A24 SLC2A10 SLC36A1 SLC15A4 COX4I1 SLC22A2 SLC9A7 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 SLC5A4

6.89e-094778114GO:0022804
GeneOntologyMolecularFunctionsymporter activity

SLC2A10 SLC36A1 SLC15A4 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC5A1 SLC5A4

9.85e-09150819GO:0015293
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC25A24 SLC2A10 SLC36A1 SLC16A6 SLC15A4 SLC22A2 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC2A1

2.74e-082938111GO:0008514
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC2A10 SLC36A1 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF SLC9A6 SLC5A4

6.98e-08188819GO:0015078
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A10 SLC23A1 SLC2A1 SLC5A1 SLC5A4

7.29e-0827815GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A10 SLC23A1 SLC2A1 SLC5A1 SLC5A4

1.07e-0729815GO:0051119
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC36A1 SLC16A6 SLC15A4 SLC22A2 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC2A1

1.59e-07207819GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC36A1 SLC16A6 SLC15A4 SLC22A2 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC2A1

1.66e-07208819GO:0005342
GeneOntologyMolecularFunctioncarbohydrate:monoatomic cation symporter activity

SLC2A10 SLC23A1 SLC5A1 SLC5A4

5.74e-0717814GO:0005402
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A10 SLC23A1 SLC2A1 SLC5A1 SLC5A4

7.33e-0742815GO:0015144
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1 SLC44A3

1.09e-0683816GO:0015101
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1E MRS2 SLC9A7 TRPV6 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

2.71e-064658111GO:0046873
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A10 SLC2A1 SLC5A1 SLC5A4

2.98e-0625814GO:0015149
GeneOntologyMolecularFunctionsolute:proton symporter activity

SLC2A10 SLC36A1 SLC15A4 SLC36A3

2.98e-0625814GO:0015295
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A10 SLC2A1 SLC5A1 SLC5A4

2.98e-0625814GO:0055056
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A10 SLC23A1 SLC2A1

3.55e-068813GO:0033300
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A7 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 SLC5A4

6.10e-06171817GO:0015081
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1

1.02e-0571815GO:0015179
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC2A10 SLC22A2 SLC23A1 SLC2A1

1.34e-0536814GO:0090482
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC5A8 SLC1A1 SLC23A1 SLC5A1 SLC5A4

1.95e-0581815GO:0015370
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1

6.82e-05105815GO:0015171
GeneOntologyMolecularFunctioncarbohydrate derivative transmembrane transporter activity

SLC25A24 SLC15A4 SLC22A2 SLC5A1

9.65e-0559814GO:1901505
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

SLC36A1 SLC16A6 SLC22A2 SLC1A1

1.10e-0461814GO:1901682
GeneOntologyMolecularFunctiontaurine transmembrane transporter activity

SLC36A1 SLC16A6

1.61e-045812GO:0005368
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC36A1 SLC36A3 SLC1A1

2.18e-0429813GO:0005416
GeneOntologyMolecularFunctionamino acid:proton symporter activity

SLC36A1 SLC36A3

2.41e-046812GO:0005280
GeneOntologyMolecularFunctionD-glucose:sodium symporter activity

SLC5A1 SLC5A4

3.37e-047812GO:0005412
GeneOntologyMolecularFunctionL-proline transmembrane transporter activity

SLC36A1 SLC36A3

3.37e-047812GO:0015193
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ATRAID SLC22A2 SLC2A1

3.51e-0434813GO:0042910
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC5A8 SLC1A1 SLC23A1

3.83e-0435813GO:0005343
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC22A2 SLC44A3

4.48e-048812GO:0015220
GeneOntologyMolecularFunctionsignal recognition particle binding

DERL3 DERL2

4.48e-048812GO:0005047
GeneOntologyMolecularFunctionL-alanine transmembrane transporter activity

SLC36A1 SLC36A3

5.74e-049812GO:0015180
GeneOntologyMolecularFunctionneutral L-amino acid transmembrane transporter activity

SLC36A1 SLC36A3 SLC1A1

6.13e-0441813GO:0015175
GeneOntologyMolecularFunctionglycine transmembrane transporter activity

SLC36A1 SLC36A3

7.16e-0410812GO:0015187
GeneOntologyMolecularFunctionhormone binding

NPR2 RXFP2 IDE ADIPOR2

8.19e-04103814GO:0042562
GeneOntologyMolecularFunctionaromatic amino acid transmembrane transporter activity

SLC36A1 SLC15A4

1.23e-0313812GO:0015173
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC15A4 SLC22A2

1.43e-0314812GO:1901474
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9A7 SLC9A6

1.43e-0314812GO:0015386
GeneOntologyMolecularFunctionpeptide hormone binding

NPR2 RXFP2 IDE

1.45e-0355813GO:0017046
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9A7 SLC9A6

1.88e-0316812GO:0015385
GeneOntologyMolecularFunctionalanine transmembrane transporter activity

SLC36A1 SLC36A3

1.88e-0316812GO:0022858
GeneOntologyMolecularFunctionlong-chain fatty acyl-CoA hydrolase activity

PPT1 PLA2G6

2.12e-0317812GO:0052816
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A7 SLC9A6

2.66e-0319812GO:0022821
GeneOntologyMolecularFunctionbasic amino acid transmembrane transporter activity

SLC15A4 SLC22A2

2.94e-0320812GO:0015174
GeneOntologyMolecularFunctionlipid transmembrane transporter activity

SLC22A2 SLC5A8 SLC2A1

3.26e-0373813GO:0170055
GeneOntologyMolecularFunctionprotein-hormone receptor activity

RXFP2 ADIPOR2

3.56e-0322812GO:0016500
GeneOntologyMolecularFunctionfatty acid transmembrane transporter activity

SLC5A8 SLC2A1

3.89e-0323812GO:0015245
GeneOntologyMolecularFunctioncytoskeletal anchor activity

ANK1 ANK2

4.23e-0324812GO:0008093
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A7 SLC9A6

5.34e-0327812GO:0051139
GeneOntologyMolecularFunctionfatty acyl-CoA hydrolase activity

PPT1 PLA2G6

5.34e-0327812GO:0047617
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1E ATP5MF TRPV6 SLC5A8 SLC1A1 ANO3 ITPR1

5.49e-03526817GO:0022803
GeneOntologyMolecularFunctionacyl-CoA hydrolase activity

PPT1 PLA2G6

5.74e-0328812GO:0016289
GeneOntologyMolecularFunctionmonocarboxylic acid transmembrane transporter activity

SLC16A6 SLC5A8 SLC2A1

5.86e-0390813GO:0008028
GeneOntologyMolecularFunctionlipid transporter activity

SLC22A2 SLC5A8 ANO3 SLC2A1

8.32e-03196814GO:0005319
GeneOntologyMolecularFunctionspectrin binding

ANK1 ANK2

8.38e-0334812GO:0030507
GeneOntologyBiologicalProcessimport across plasma membrane

SLC2A10 CACNA1E THBS1 SLC36A1 SLC15A4 SLC22A2 SLC9A7 TRPV6 SLC1A1 SLC9A6 SLC2A1 SLC5A1

6.30e-112307812GO:0098739
GeneOntologyBiologicalProcessorganic acid transmembrane transport

THBS1 SLC36A1 SLC16A6 SLC15A4 SLC22A2 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC2A1

7.23e-101677810GO:1903825
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC2A10 CACNA1E SLC36A1 ANK1 ANK2 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC5A1 ITPR1 SLC5A4

7.79e-1010177820GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transport

SLC2A10 CACNA1E SLC36A1 ANK2 MRS2 SLC15A4 COX4I1 CYSLTR1 SLC22A2 SLC9A7 UMOD SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

1.14e-0911577821GO:0006812
GeneOntologyBiologicalProcessmonoatomic ion transport

SLC2A10 CACNA1E SLC36A1 ANK2 MRS2 SLC15A4 COX4I1 CYSLTR1 SLC22A2 SLC9A7 UMOD SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC5A1 ITPR1 SLC5A4

4.26e-0913747822GO:0006811
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

SLC2A10 CACNA1E SLC36A1 ANK1 ANK2 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

7.26e-099227818GO:0098662
GeneOntologyBiologicalProcessorganic anion transport

SLC25A24 SLC2A10 THBS1 SLC36A1 SLC16A6 SLC15A4 SLC22A2 UMOD SLC36A3 PLA2G6 SLC5A8 SLC1A1 SLC23A1 SLC2A1

7.27e-095157814GO:0015711
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

THBS1 SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC5A8 SLC1A1 SLC23A1 SLC2A1

1.10e-08163789GO:1905039
GeneOntologyBiologicalProcessproton transmembrane transport

SLC2A10 SLC36A1 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF SLC9A6 SLC5A4

1.59e-08170789GO:1902600
GeneOntologyBiologicalProcesscarboxylic acid transport

THBS1 SLC36A1 SLC16A6 SLC15A4 SLC22A2 UMOD SLC36A3 PLA2G6 SLC5A8 SLC1A1 SLC23A1 SLC2A1

4.31e-084107812GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

THBS1 SLC36A1 SLC16A6 SLC15A4 SLC22A2 UMOD SLC36A3 PLA2G6 SLC5A8 SLC1A1 SLC23A1 SLC2A1

4.55e-084127812GO:0015849
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC2A10 CACNA1E SLC36A1 ANK2 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

6.42e-089427817GO:0098655
GeneOntologyBiologicalProcessimport into cell

SORT1 SLC2A10 CACNA1E THBS1 SLC36A1 ANK2 PPT1 SLC15A4 TM9SF4 INPPL1 SLC22A2 SLC9A7 PLA2G6 TRPV6 SLC1A1 SLC9A6 SLC2A1 SLC5A1

7.49e-0810747818GO:0098657
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

SLC2A10 CACNA1E SLC36A1 ANK2 MRS2 SLC15A4 COX4I1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC1A1 SLC23A1 ANO3 SLC9A6 SLC5A1 ITPR1 SLC5A4

1.31e-0711157818GO:0034220
GeneOntologyBiologicalProcessD-glucose import across plasma membrane

SLC2A10 SLC2A1 SLC5A1

5.17e-075783GO:0098708
GeneOntologyBiologicalProcesscarbohydrate import across plasma membrane

SLC2A10 SLC2A1 SLC5A1

1.03e-066783GO:0098704
GeneOntologyBiologicalProcesshexose import across plasma membrane

SLC2A10 SLC2A1 SLC5A1

1.03e-066783GO:0140271
GeneOntologyBiologicalProcessmonosaccharide transmembrane transport

SORT1 SLC2A10 SLC23A1 SLC2A1 ADIPOR2 SLC5A1 SLC5A4

1.91e-06154787GO:0015749
GeneOntologyBiologicalProcesscarbohydrate transmembrane transport

SORT1 SLC2A10 SLC23A1 SLC2A1 ADIPOR2 SLC5A1 SLC5A4

3.41e-06168787GO:0034219
GeneOntologyBiologicalProcessdehydroascorbic acid transport

SLC2A10 SLC23A1 SLC2A1

4.30e-069783GO:0070837
GeneOntologyBiologicalProcesscarbohydrate transport

SORT1 SLC2A10 SLC23A1 SLC2A1 ADIPOR2 SLC5A1 SLC5A4

6.67e-06186787GO:0008643
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1E ANK1 ANK2 PPT1 OBP2A TBC1D1 TM9SF4 SLC9A7 UMOD PLA2G6 TRPV6 C1QTNF3 SLC1A1 SLC9A6 ADIPOR2 ITPR1

1.44e-0512497816GO:0048878
GeneOntologyBiologicalProcesscellular homeostasis

SLC2A10 CACNA1E ANK2 PPT1 TBC1D1 TM9SF4 SLC9A7 UMOD PLA2G6 C1QTNF3 IDE SLC1A1 SLC9A6 ITPR1

1.64e-059817814GO:0019725
GeneOntologyBiologicalProcessorganic cation transport

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1 SLC44A3

1.84e-05145786GO:0015695
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLC2A10 SLC22A2 SLC1A1 SLC2A1 SLC5A1

1.97e-0587785GO:0150104
GeneOntologyBiologicalProcessmetal ion transport

CACNA1E ANK2 MRS2 CYSLTR1 SLC9A7 UMOD TRPV6 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC5A1 ITPR1 SLC5A4

2.04e-0510007814GO:0030001
GeneOntologyBiologicalProcessD-glucose transmembrane transport

SORT1 SLC2A10 SLC2A1 ADIPOR2 SLC5A1 SLC5A4

2.07e-05148786GO:1904659
GeneOntologyBiologicalProcessvascular transport

SLC2A10 SLC22A2 SLC1A1 SLC2A1 SLC5A1

2.08e-0588785GO:0010232
GeneOntologyBiologicalProcesshexose transmembrane transport

SORT1 SLC2A10 SLC2A1 ADIPOR2 SLC5A1 SLC5A4

2.32e-05151786GO:0008645
GeneOntologyBiologicalProcessL-amino acid transport

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1

5.59e-05108785GO:0015807
GeneOntologyBiologicalProcessvitamin transport

SLC2A10 SLC22A2 SLC23A1 SLC2A1

5.99e-0556784GO:0051180
GeneOntologyBiologicalProcessfatty acid transmembrane transport

THBS1 SLC5A8 SLC2A1

7.61e-0522783GO:1902001
GeneOntologyBiologicalProcesssodium ion transport

SLC9A7 UMOD SLC5A8 SLC23A1 SLC9A6 SLC5A1 SLC5A4

8.18e-05275787GO:0006814
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1

9.22e-05120785GO:0003333
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1E ANK2 PPT1 TBC1D1 TM9SF4 SLC9A7 UMOD PLA2G6 C1QTNF3 SLC1A1 SLC9A6 ITPR1

9.41e-058667812GO:0055082
GeneOntologyBiologicalProcesscirculatory system process

SLC2A10 CACNA1E NPR2 ANK2 CYSLTR1 SLC22A2 UMOD PLA2G6 SLC1A1 SLC2A1 SLC5A1

9.42e-057337811GO:0003013
GeneOntologyBiologicalProcesssulfur compound transport

SLC36A1 SLC16A6 SLC22A2 SLC1A1

1.08e-0465784GO:0072348
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

SLC9A7 SLC9A6 SLC5A1

1.43e-0427783GO:0098719
GeneOntologyBiologicalProcessregulation of protein exit from endoplasmic reticulum

TM9SF4 DERL3 DERL2

1.43e-0427783GO:0070861
GeneOntologyBiologicalProcessfatty acid transport

THBS1 SLC22A2 PLA2G6 SLC5A8 SLC2A1

1.44e-04132785GO:0015908
GeneOntologyBiologicalProcessmonocarboxylic acid transport

THBS1 SLC16A6 SLC22A2 PLA2G6 SLC5A8 SLC2A1

1.56e-04213786GO:0015718
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1E SLC9A7 TRPV6 SLC9A6 SLC5A1

2.03e-04142785GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1E SLC9A7 TRPV6 SLC9A6 SLC5A1

2.03e-04142785GO:0098659
GeneOntologyBiologicalProcessgalactose transmembrane transport

SLC2A10 SLC5A1

2.10e-046782GO:0015757
GeneOntologyBiologicalProcessregulation of establishment of protein localization

CACNA1E TBC1D1 TM9SF4 DERL3 DERL2 UMOD PLA2G6 C1QTNF3 SLC1A1 ITPR1

2.21e-046747810GO:0070201
GeneOntologyBiologicalProcessregulation of protein transport

CACNA1E TBC1D1 TM9SF4 DERL3 DERL2 UMOD PLA2G6 C1QTNF3 ITPR1

2.59e-04560789GO:0051223
GeneOntologyBiologicalProcessresponse to luteinizing hormone

CYP1B1 NPR2

2.93e-047782GO:0034699
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

ANK1 ANK2 PPT1 TM9SF4 SLC9A7 UMOD TRPV6 SLC1A1 SLC9A6 ITPR1

3.16e-047057810GO:0055080
GeneOntologyBiologicalProcessvascular process in circulatory system

SLC2A10 CYSLTR1 SLC22A2 PLA2G6 SLC1A1 SLC2A1 SLC5A1

3.23e-04344787GO:0003018
GeneOntologyBiologicalProcessL-alpha-amino acid transmembrane transport

SLC36A1 SLC15A4 SLC22A2 SLC1A1

3.32e-0487784GO:1902475
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

ANK1 ANK2 PPT1 TM9SF4 SLC9A7 UMOD TRPV6 SLC1A1 SLC9A6 ITPR1

3.61e-047177810GO:0050801
GeneOntologyBiologicalProcessalkanesulfonate transmembrane transport

SLC36A1 SLC16A6

3.90e-048782GO:0042918
GeneOntologyBiologicalProcesstaurine transmembrane transport

SLC36A1 SLC16A6

3.90e-048782GO:0015734
GeneOntologyBiologicalProcesstransepithelial transport

SLC1A1 SLC5A1 ITPR1

3.99e-0438783GO:0070633
GeneOntologyBiologicalProcessregulation of intracellular pH

PPT1 TM9SF4 SLC9A7 SLC9A6

4.46e-0494784GO:0051453
GeneOntologyBiologicalProcessmetanephros development

GREB1L APH1B UMOD SLC5A1

4.64e-0495784GO:0001656
GeneOntologyBiologicalProcessnegative regulation of retrograde protein transport, ER to cytosol

DERL3 DERL2

5.00e-049782GO:1904153
GeneOntologyBiologicalProcessregulation of cellular pH

PPT1 TM9SF4 SLC9A7 SLC9A6

5.85e-04101784GO:0030641
GeneOntologyBiologicalProcessnegative regulation of protein exit from endoplasmic reticulum

DERL3 DERL2

6.23e-0410782GO:0070862
GeneOntologyBiologicalProcesscholine transport

SLC22A2 SLC44A3

6.23e-0410782GO:0015871
GeneOntologyBiologicalProcessorganophosphate biosynthetic process

NPR2 PPT1 ACLY INPPL1 DOLK PLA2G6 ATP5MF SLC5A8 SLC44A3

7.13e-04644789GO:0090407
GeneOntologyBiologicalProcessproline transmembrane transport

SLC36A1 SLC36A3

7.60e-0411782GO:0035524
GeneOntologyBiologicalProcessurate transport

UMOD SLC23A1

7.60e-0411782GO:0015747
GeneOntologyBiologicalProcessL-alanine transport

SLC36A1 SLC36A3

7.60e-0411782GO:0015808
GeneOntologyBiologicalProcessamino acid transport

SLC36A1 SLC15A4 SLC22A2 SLC36A3 SLC1A1

8.66e-04195785GO:0006865
GeneOntologyBiologicalProcessresponse to endoplasmic reticulum stress

THBS1 DERL3 DERL2 UMOD PLA2G6 ITPR1

8.82e-04295786GO:0034976
GeneOntologyBiologicalProcessresponse to nitrogen compound

SORT1 CYP1B1 THBS1 NPR2 OBP2A INPPL1 DERL3 DERL2 UMOD IDE SLC1A1 SLC2A1 ITPR1

9.08e-0412727813GO:1901698
GeneOntologyBiologicalProcesslong-chain fatty acid import across plasma membrane

THBS1 SLC2A1

9.09e-0412782GO:0015911
GeneOntologyBiologicalProcessepithelial fluid transport

SLC5A1 ITPR1

9.09e-0412782GO:0042045
GeneOntologyBiologicalProcessprotein exit from endoplasmic reticulum

TM9SF4 DERL3 DERL2

9.51e-0451783GO:0032527
GeneOntologyBiologicalProcessregulation of pH

PPT1 TM9SF4 SLC9A7 SLC9A6

1.12e-03120784GO:0006885
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC9A7 SLC23A1 SLC9A6 SLC5A1 SLC5A4

1.16e-03208785GO:0035725
GeneOntologyBiologicalProcessregulation of retrograde protein transport, ER to cytosol

DERL3 DERL2

1.25e-0314782GO:1904152
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1E THBS1 UMOD SLC1A1

1.34e-03126784GO:0033555
GeneOntologyBiologicalProcessamino acid import across plasma membrane

SLC36A1 SLC22A2 SLC1A1

1.38e-0358783GO:0089718
GeneOntologyBiologicalProcesschloride transport

SLC5A8 SLC1A1 ANO3 SLC5A1

1.42e-03128784GO:0006821
GeneOntologyBiologicalProcessregulation of cGMP-mediated signaling

THBS1 NPR2

1.44e-0315782GO:0010752
GeneOntologyBiologicalProcessazole transmembrane transport

SLC15A4 SLC22A2

1.44e-0315782GO:0045117
GeneOntologyBiologicalProcessregulation of toll-like receptor 9 signaling pathway

PPT1 SLC15A4

1.44e-0315782GO:0034163
GeneOntologyBiologicalProcessglycine transport

SLC36A1 SLC36A3

1.44e-0315782GO:0015816
GeneOntologyBiologicalProcessneutral amino acid transport

SLC36A1 SLC36A3 SLC1A1

1.52e-0360783GO:0015804
GeneOntologyBiologicalProcessL-ascorbic acid metabolic process

SLC23A1 SLC2A1

1.64e-0316782GO:0019852
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC5A8 SLC1A1 ANO3 SLC5A1

1.68e-03134784GO:0098661
GeneOntologyBiologicalProcessmembrane lipid metabolic process

CERKL CYP1B1 PPT1 GAL3ST4 PLA2G6

1.77e-03229785GO:0006643
GeneOntologyBiologicalProcessglucose homeostasis

CACNA1E OBP2A TBC1D1 PLA2G6 C1QTNF3 ADIPOR2

1.77e-03338786GO:0042593
GeneOntologyBiologicalProcesscarbohydrate homeostasis

CACNA1E OBP2A TBC1D1 PLA2G6 C1QTNF3 ADIPOR2

1.79e-03339786GO:0033500
GeneOntologyBiologicalProcessresponse to hormone

SORT1 CYP1B1 THBS1 NPR2 OBP2A INPPL1 RXFP2 IDE MSI1 SLC2A1 ADIPOR2

1.81e-0310427811GO:0009725
GeneOntologyBiologicalProcessxenobiotic transport

ATRAID SLC22A2 SLC2A1

1.84e-0364783GO:0042908
GeneOntologyCellularComponentbasal plasma membrane

ANK1 ANK2 SLC16A6 INPPL1 SLC22A2 UMOD IDE SLC23A1 SLC2A1

9.24e-06354819GO:0009925
GeneOntologyCellularComponentbasal part of cell

ANK1 ANK2 SLC16A6 INPPL1 SLC22A2 UMOD IDE SLC23A1 SLC2A1

1.56e-05378819GO:0045178
GeneOntologyCellularComponentapical plasma membrane

SLC36A1 ANK2 SLC22A2 UMOD SLC5A8 SLC1A1 SLC23A1 SLC2A1 SLC5A1

1.11e-04487819GO:0016324
GeneOntologyCellularComponentbasolateral plasma membrane

ANK1 ANK2 SLC16A6 SLC22A2 UMOD IDE SLC2A1

2.43e-04320817GO:0016323
GeneOntologyCellularComponentapical part of cell

SLC36A1 ANK2 SLC22A2 UMOD SLC5A8 SLC1A1 SLC23A1 SLC2A1 SLC5A1

4.69e-04592819GO:0045177
GeneOntologyCellularComponentearly endosome

SORT1 ANK2 SLC15A4 TM9SF4 DERL2 SLC1A1 SLC9A6 SLC5A1

5.48e-04481818GO:0005769
GeneOntologyCellularComponenttransport vesicle

SORT1 PHAF1 APH1B SEC24D PPT1 SLC22A2 SLC35F1 ITPR1

8.99e-04519818GO:0030133
GeneOntologyCellularComponenttransport vesicle membrane

PHAF1 SEC24D PPT1 SLC22A2 SLC35F1 ITPR1

9.69e-04293816GO:0030658
DomainNA_SOLUT_SYMP_1

SLC5A8 SLC5A1 SLC5A4

1.17e-0511793PS00456
DomainNA_SOLUT_SYMP_2

SLC5A8 SLC5A1 SLC5A4

1.56e-0512793PS00457
DomainSSF

SLC5A8 SLC5A1 SLC5A4

1.56e-0512793PF00474
DomainNa/solute_symporter

SLC5A8 SLC5A1 SLC5A4

1.56e-0512793IPR001734
DomainNA_SOLUT_SYMP_3

SLC5A8 SLC5A1 SLC5A4

1.56e-0512793PS50283
DomainMFS_dom

SLC2A10 SLC16A6 SLC15A4 SLC22A2 MFSD6L SLC2A1

2.21e-05134796IPR020846
DomainSUGAR_TRANSPORT_2

SLC2A10 SLC22A2 SLC2A1

4.75e-0517793PS00217
DomainDER1

DERL3 DERL2

5.29e-053792IPR007599
DomainNa/H_exchanger_6

SLC9A7 SLC9A6

5.29e-053792IPR002090
DomainEGF_3

THBS1 THBS2 ATRAID ATRNL1 UMOD C9 TENM2

6.13e-05235797PS50026
DomainEGF-like_dom

THBS1 THBS2 ATRAID ATRNL1 UMOD C9 TENM2

8.81e-05249797IPR000742
DomainMFS

SLC2A10 SLC16A6 SLC22A2 MFSD6L SLC2A1

9.45e-05108795PS50850
DomainEGF_1

THBS1 THBS2 ATRAID ATRNL1 UMOD C9 TENM2

1.02e-04255797PS00022
DomainEGF-like_CS

THBS1 THBS2 ATRAID ATRNL1 UMOD C9 TENM2

1.18e-04261797IPR013032
DomainEGF_2

THBS1 THBS2 ATRAID ATRNL1 UMOD C9 TENM2

1.30e-04265797PS01186
DomainSUGAR_TRANSPORT_1

SLC2A10 SLC22A2 SLC2A1

1.38e-0424793PS00216
DomainTSP_3

THBS1 THBS2

1.75e-045792PF02412
DomainTSP3

THBS1 THBS2

1.75e-045792PS51234
DomainTSP_CTER

THBS1 THBS2

1.75e-045792PS51236
Domain-

THBS1 THBS2

1.75e-0457924.10.1080.10
DomainThrombospondin_C

THBS1 THBS2

1.75e-045792IPR008859
DomainTSP_C

THBS1 THBS2

1.75e-045792PF05735
DomainThrombospondin_3_rpt

THBS1 THBS2

1.75e-045792IPR017897
DomainThrombospondin_3-like_rpt

THBS1 THBS2

1.75e-045792IPR003367
DomainTSP_type-3_rpt

THBS1 THBS2

1.75e-045792IPR028974
DomainSugar_transporter_CS

SLC2A10 SLC22A2 SLC2A1

3.31e-0432793IPR005829
DomainMFS_sugar_transport-like

SLC2A10 SLC22A2 SLC2A1

4.70e-0436793IPR005828
DomainSugar_tr

SLC2A10 SLC22A2 SLC2A1

4.70e-0436793PF00083
DomainEGF

THBS1 THBS2 ATRAID ATRNL1 UMOD TENM2

4.81e-04235796SM00181
DomainNa/solute_symporter_CS

SLC5A1 SLC5A4

4.87e-048792IPR018212
DomainNaH_exchanger

SLC9A7 SLC9A6

6.24e-049792IPR004709
DomainZU5

ANK1 ANK2

6.24e-049792SM00218
DomainZU5

ANK1 ANK2

7.78e-0410792PS51145
DomainCation/H_exchanger_CPA1

SLC9A7 SLC9A6

9.48e-0411792IPR018422
DomainEGF_3

THBS2 UMOD

1.13e-0312792PF12947
DomainEGF_dom

THBS2 UMOD

1.13e-0312792IPR024731
DomainZU5

ANK1 ANK2

1.13e-0312792PF00791
DomainZU5_dom

ANK1 ANK2

1.13e-0312792IPR000906
DomainNa_H_Exchanger

SLC9A7 SLC9A6

1.56e-0314792PF00999
DomainCation/H_exchanger

SLC9A7 SLC9A6

1.56e-0314792IPR006153
DomainSugar/inositol_transpt

SLC2A10 SLC2A1

1.56e-0314792IPR003663
DomainEGF_CA

THBS1 THBS2 UMOD TENM2

1.78e-03122794SM00179
DomainEGF-like_Ca-bd_dom

THBS1 THBS2 UMOD TENM2

1.89e-03124794IPR001881
DomainAa_trans

SLC36A1 SLC36A3

2.31e-0317792PF01490
DomainAA_transpt_TM

SLC36A1 SLC36A3

2.31e-0317792IPR013057
DomainTSP_1

THBS1 THBS2 C9

2.41e-0363793PF00090
DomainTSP1

THBS1 THBS2 C9

2.63e-0365793SM00209
DomainTSP1_rpt

THBS1 THBS2 C9

2.63e-0365793IPR000884
DomainTSP1

THBS1 THBS2 C9

2.63e-0365793PS50092
Domain6-PGluconate_DH_C-like

EHHADH PYCR1

2.88e-0319792IPR008927
DomainTSPN

THBS1 THBS2

4.22e-0323792SM00210
DomainTM4_1

TSPAN11 TSPAN7

5.38e-0326792PS00421
Domain-

EHHADH ACLY UBA6 PYCR1

5.74e-031697943.40.50.720
DomainDEATH

ANK1 ANK2

5.79e-0327792SM00005
DomainEGF_CA

THBS1 THBS2 UMOD

5.79e-0386793PF07645
DomainVWC

THBS1 THBS2

6.22e-0328792PF00093
DomainNAD(P)-bd_dom

EHHADH ACLY UBA6 PYCR1

6.23e-03173794IPR016040
DomainTetraspanin

TSPAN11 TSPAN7

8.07e-0332792IPR000301
DomainTetraspanin_EC2

TSPAN11 TSPAN7

8.07e-0332792IPR008952
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A10 SLC36A1 SLC15A4 SLC22A2 SLC9A7 SLC5A8 SLC1A1 SLC9A6 SLC2A1 SLC44A3 SLC5A1 SLC5A4

2.78e-102386012MM15076
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC2A10 SLC36A1 SLC15A4 SLC22A2 SLC9A7 SLC5A8 SLC1A1 SLC9A6 SLC2A1 SLC44A3 SLC5A1 SLC5A4

4.68e-102496012M5988
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC2A10 SLC36A1 MRS2 SLC15A4 DERL3 SLC22A2 DERL2 SLC9A7 TRPV6 SLC5A8 SLC1A1 ANO3 SLC9A6 SLC2A1 SLC44A3 SLC5A1 SLC5A4

1.92e-096816017MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC2A10 SLC36A1 MRS2 SLC15A4 DERL3 SLC22A2 DERL2 SLC9A7 TRPV6 SLC5A8 SLC1A1 ANO3 SLC9A6 SLC2A1 SLC44A3 SLC5A1 SLC5A4

6.19e-097366017M27287
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A10 SLC2A1 SLC5A1 SLC5A4

1.10e-0619604MM14718
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A10 SLC2A1 SLC5A1 SLC5A4

1.68e-0621604M27058
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

SLC22A2 SLC5A8 SLC1A1 SLC2A1 SLC5A1

4.16e-0657605M39812
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC36A1 SLC15A4 SLC9A7 SLC5A8 SLC1A1 SLC9A6

6.29e-06108606M823
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC36A1 SLC15A4 SLC9A7 SLC5A8 SLC1A1 SLC9A6

6.64e-06109606MM15074
PathwayREACTOME_DISORDERS_OF_TRANSMEMBRANE_TRANSPORTERS

SLC2A10 DERL3 DERL2 SLC1A1 SLC9A6 SLC2A1 SLC5A1

9.63e-06177607M27476
PathwayREACTOME_SLC_TRANSPORTER_DISORDERS

SLC2A10 SLC1A1 SLC9A6 SLC2A1 SLC5A1

6.21e-0599605M27474
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1E ACLY SLC2A1 ADIPOR2 ITPR1

9.39e-05108605M17034
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1E SLC2A1 ADIPOR2 ITPR1

2.46e-0472604MM14631
PathwayWP_NRF2_PATHWAY

SLC2A10 SLC5A8 SLC2A1 SLC5A1 SLC5A4

3.27e-04141605M39454
PathwayWP_NUCLEAR_RECEPTORS_METAPATHWAY

SLC2A10 CYP1B1 EHHADH SLC5A8 SLC2A1 SLC5A1 SLC5A4

3.57e-04314607M39428
PathwayREACTOME_VITAMIN_C_ASCORBATE_METABOLISM

SLC23A1 SLC2A1

4.91e-048602M27091
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A7 SLC9A6

6.29e-049602M27337
PathwayREACTOME_SODIUM_PROTON_EXCHANGERS

SLC9A7 SLC9A6

6.29e-049602MM15079
PathwayREACTOME_VITAMIN_C_ASCORBATE_METABOLISM

SLC23A1 SLC2A1

6.29e-049602MM14769
PathwayWP_METABOLIC_REPROGRAMMING_IN_COLON_CANCER

ACLY PYCR1 SLC2A1

7.48e-0442603M39740
PathwayBIOCARTA_VITCB_PATHWAY

SLC23A1 SLC2A1

9.56e-0411602M15422
PathwayBIOCARTA_VITCB_PATHWAY

SLC23A1 SLC2A1

1.14e-0312602MM1526
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLC2A10 SLC22A2 SLC1A1 SLC2A1 SLC5A1

4.86e-0610581530280653
Pubmed

Induced thrombospondin expression in the mouse pancreas during pancreatic injury.

THBS1 THBS2

5.36e-06281216181801
Pubmed

Immunochemical analysis of the structure of the signature domains of thrombospondin-1 and thrombospondin-2 in low calcium concentrations.

THBS1 THBS2

5.36e-06281217620335
Pubmed

A membrane-proximal region in the C-terminal tail of NHE7 is required for its distribution in the trans-Golgi network, distinct from NHE6 localization at endosomes.

SLC9A7 SLC9A6

5.36e-06281220364249
Pubmed

Human cytomegalovirus infection modulates thrombospondins 1 and 2 in primary fetal astrocytes.

THBS1 THBS2

5.36e-06281223660684
Pubmed

Molecular cloning and characterization of a novel (Na+,K+)/H+ exchanger localized to the trans-Golgi network.

SLC9A7 SLC9A6

5.36e-06281211279194
Pubmed

Increased excitatory connectivity and epileptiform activity in thrombospondin1/2 knockout mice following cortical trauma.

THBS1 THBS2

5.36e-06281239122122
Pubmed

Compound deletion of thrombospondin-1 and -2 results in a skeletal phenotype not predicted by the single gene knockouts.

THBS1 THBS2

5.36e-06281234425286
Pubmed

Thrombospondin-1 (TSP1)-null and TSP2-null mice exhibit lower intraocular pressures.

THBS1 THBS2

5.36e-06281222930728
Pubmed

Modulation of thrombospondin expression during differentiation of embryonal carcinoma cells.

THBS1 THBS2

5.36e-0628128126073
Pubmed

THBS1 and THBS2 Enhance the In Vitro Proliferation, Adhesion, Migration and Invasion of Intrahepatic Cholangiocarcinoma Cells.

THBS1 THBS2

5.36e-06281238339060
Pubmed

The CTRP3-AdipoR2 Axis Regulates the Development of Experimental Autoimmune Encephalomyelitis by Suppressing Th17 Cell Differentiation.

C1QTNF3 ADIPOR2

5.36e-06281234925309
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Temporal Lobe Epilepsy Before and After Surgery.

THBS1 THBS2

5.36e-06281233372257
Pubmed

An association study of thrombospondin 1 and 2 SNPs with coronary artery disease and myocardial infarction among South Indians.

THBS1 THBS2

5.36e-06281221762961
Pubmed

Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1.

THBS1 THBS2

5.36e-0628129694593
Pubmed

Cholinergic augmentation of insulin release requires ankyrin-B.

ANK2 ITPR1

5.36e-06281220234002
Pubmed

Inositol 1,4,5-trisphosphate receptor localization and stability in neonatal cardiomyocytes requires interaction with ankyrin-B.

ANK2 ITPR1

5.36e-06281214722080
Pubmed

The lack of thrombospondin-1 (TSP1) dictates the course of wound healing in double-TSP1/TSP2-null mice.

THBS1 THBS2

5.36e-06281212213711
Pubmed

Thrombospondin expression in aldosterone-producing adenomas.

THBS1 THBS2

5.36e-06281212358136
Pubmed

Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice.

ANK1 ANK2

5.36e-0628128471772
Pubmed

A second, expressed thrombospondin gene (Thbs2) exists in the mouse genome.

THBS1 THBS2

5.36e-0628121712771
Pubmed

Structure and mechanism of the SGLT family of glucose transporters.

SLC5A8 SLC5A1

5.36e-06281234880492
Pubmed

Prognostic impact of the combination of glucose transporter 1 and ATP citrate lyase in node-negative patients with non-small lung cancer.

ACLY SLC2A1

5.36e-06281225837797
Pubmed

Expression of thrombospondin-1 in ischemia-induced retinal neovascularization.

THBS1 THBS2

5.36e-06281210027393
Pubmed

Ankyrin B modulates the function of Na,K-ATPase/inositol 1,4,5-trisphosphate receptor signaling microdomain.

ANK2 ITPR1

5.36e-06281218303017
Pubmed

Contribution of Thrombospondin-1 and -2 to Lipopolysaccharide-Induced Acute Respiratory Distress Syndrome.

THBS1 THBS2

5.36e-06281233981184
Pubmed

Thrombospondins 1 and 2 are necessary for synaptic plasticity and functional recovery after stroke.

THBS1 THBS2

5.36e-06281218594557
Pubmed

A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect.

DERL3 SLC2A1

5.36e-06281224699711
Pubmed

Roles of thrombospondin-1 and -2 in regulating corneal and iris angiogenesis.

THBS1 THBS2

5.36e-06281215037577
Pubmed

TSP1 and TSP2 Have Unique and Overlapping Roles in Protecting against Noise-Induced Auditory Synaptopathy.

THBS1 THBS2

5.36e-06281230928339
Pubmed

Thrombospondins deployed by thrombopoietic cells determine angiogenic switch and extent of revascularization.

THBS1 THBS2

5.36e-06281217143334
Pubmed

Circulating Levels of Thrombospondin-1 and Thrombospondin-2 in Patients with Common Brain Tumors.

THBS1 THBS2

5.36e-06281233759165
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC22A2 SLC1A1 SLC2A1 SLC5A1

6.79e-065281426590417
Pubmed

Increased sensitivity to kindling in mice lacking TSP1.

THBS1 THBS2

1.60e-05381226241338
Pubmed

Expression and function of thrombospondin-1 in myelinating glial cells of the central nervous system.

THBS1 THBS2

1.60e-0538129373030
Pubmed

Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury.

THBS1 THBS2

1.60e-05381218787106
Pubmed

Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency.

ANK2 ITPR1

1.60e-05381226168218
Pubmed

Thrombospondins use the VLDL receptor and a nonapoptotic pathway to inhibit cell division in microvascular endothelial cells.

THBS1 THBS2

1.60e-05381218032585
Pubmed

Gabapentin receptor alpha2delta-1 is a neuronal thrombospondin receptor responsible for excitatory CNS synaptogenesis.

THBS1 THBS2

1.60e-05381219818485
Pubmed

EWS/FLI1 regulates tumor angiogenesis in Ewing's sarcoma via suppression of thrombospondins.

THBS1 THBS2

1.60e-05381217638877
Pubmed

TSP1 and TSP2 deficiencies affect LOX protein distribution in the femoral diaphysis and pro-peptide removal in marrow-derived mesenchymal stem cells in vitro.

THBS1 THBS2

1.60e-05381230939949
Pubmed

Akt substrate TBC1D1 regulates GLUT1 expression through the mTOR pathway in 3T3-L1 adipocytes.

TBC1D1 SLC2A1

1.60e-05381218215134
Pubmed

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.

ANK1 ANK2

1.60e-05381212527750
Pubmed

Organization and expression of the SLC36 cluster of amino acid transporter genes.

SLC36A1 SLC36A3

1.60e-05381215058382
Pubmed

A cluster of proton/amino acid transporter genes in the human and mouse genomes.

SLC36A1 SLC36A3

1.60e-05381212809675
Pubmed

Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.

ANK1 ANK2

1.60e-05381221177872
Pubmed

Interactions between CD47 and thrombospondin reduce inflammation.

THBS1 THBS2

1.60e-05381217442977
Pubmed

Differential interactions of thrombospondin-1, -2, and -4 with CD47 and effects on cGMP signaling and ischemic injury responses.

THBS1 THBS2

1.60e-05381219004835
Pubmed

Human umbilical cord mesenchymal stem cell-derived exosomal miR-214-3p regulates the progression of gallbladder cancer by regulating ACLY/GLUT1.

ACLY SLC2A1

1.60e-05381237747441
Pubmed

Thrombospondin is a tight-binding competitive inhibitor of neutrophil elastase.

THBS1 THBS2

1.60e-0538128463250
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS1 THBS2

1.60e-05381212482844
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS1 THBS2

1.60e-05381226168731
Pubmed

Human ankyrins and their contribution to disease biology: An update.

ANK1 ANK2

1.60e-05381233410423
Pubmed

Reduced expression of thrombospondins and craniofacial dysmorphism in mice overexpressing Fra1.

THBS1 THBS2

1.60e-05381216598380
Pubmed

Differential Expression Pattern of THBS1 and THBS2 in Lung Cancer: Clinical Outcome and a Systematic-Analysis of Microarray Databases.

THBS1 THBS2

1.60e-05381227513329
Pubmed

Characterization and modulation of glucose uptake in a human blood-brain barrier model.

SLC2A1 SLC5A1

1.60e-05381223975336
Pubmed

Regulation of VEGF-A, VEGFR-I, thrombospondin-1, -2, and -3 expression in a human pituitary cell line (HP75) by TGFbeta1, bFGF, and EGF.

THBS1 THBS2

1.60e-05381215347840
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS1 THBS2

1.60e-05381225976449
Pubmed

Localization of Glucose Transporter 10 to Hair Cells' Cuticular Plate in the Mouse Inner Ear.

SLC2A10 SLC2A1

1.60e-05381230013986
Pubmed

Differential regulation of mouse kidney sodium-dependent transporters mRNA by cadmium.

SLC5A1 SLC5A4

1.60e-05381211749115
Pubmed

The Pathological Significance and Prognostic Roles of Thrombospondin-1, and -2, and 4N1K-peptide in Bladder Cancer.

THBS1 THBS2

1.60e-05381231092423
Pubmed

mRNA Expression of thrombospondin 1, 2 and 3 from proximal to distal in human abdominal aortic aneurysm - preliminary report.

THBS1 THBS2

1.60e-05381234669362
Pubmed

Thrombospondin 1 and thrombospondin 2 are expressed as both homo- and heterotrimers.

THBS1 THBS2

1.60e-0538121459996
Pubmed

Cyp1B1 expression promotes angiogenesis by suppressing NF-κB activity.

CYP1B1 THBS2

1.60e-05381224088896
Pubmed

Post-oral appetite stimulation by sugars and nonmetabolizable sugar analogs.

SLC5A1 SLC5A4

1.60e-05381223926132
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS1 THBS2

1.60e-05381218178577
Pubmed

Differential expression of thrombospondin 1, 2, and 3 during murine development.

THBS1 THBS2

1.60e-0538128400410
Pubmed

Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.

ANK1 ANK2

1.60e-05381234289389
Pubmed

MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth.

ANK1 ANK2

1.60e-05381216597699
Pubmed

Cocaine Triggers Astrocyte-Mediated Synaptogenesis.

THBS1 THBS2

1.60e-05381233069367
Pubmed

New loci associated with kidney function and chronic kidney disease.

SORT1 SLC22A2 UMOD C9

1.76e-056681420383146
Pubmed

Genetic variability of the fatty acid synthase pathway is not associated with prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).

SLC5A8 SLC2A1 SLC5A1

1.82e-052281320965718
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

SLC25A24 CYP1B1 SEC24D THBS2 ACLY COX4I1 PYCR1 ATP5MF CTIF CMTM7 SLC9A6 SLC2A1 ITPR1

2.94e-051451811330550785
Pubmed

Thrombospondin 2 potentiates notch3/jagged1 signaling.

THBS1 THBS2

3.20e-05481219147503
Pubmed

Expression of glucose transporters in duodenal mucosa of patients with type 1 diabetes.

SLC2A1 SLC5A1

3.20e-05481232617672
Pubmed

Derlin-3 Is Required for Changes in ERAD Complex Formation under ER Stress.

DERL3 DERL2

3.20e-05481232858914
Pubmed

A membrane protein required for dislocation of misfolded proteins from the ER.

DERL3 DERL2

3.20e-05481215215855
Pubmed

Organellar Na+/H+ exchangers: novel players in organelle pH regulation and their emerging functions.

SLC9A7 SLC9A6

3.20e-05481221171650
Pubmed

WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.

TBC1D1 SLC2A1

3.20e-05481231816312
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS1 THBS2

3.20e-0548126338048
Pubmed

Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline.

THBS1 THBS2

3.20e-05481218089612
Pubmed

Recognition of the N-terminal modules of thrombospondin-1 and thrombospondin-2 by alpha6beta1 integrin.

THBS1 THBS2

3.20e-05481212909644
Pubmed

Interactions of thrombospondins with alpha4beta1 integrin and CD47 differentially modulate T cell behavior.

THBS1 THBS2

3.20e-05481211980922
Pubmed

Thrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activity.

THBS1 THBS2

3.20e-05481210900205
Pubmed

Spontaneous bacterial keratitis in CD36 knockout mice.

THBS1 THBS2

3.20e-05481220847111
Pubmed

Hereditary Dystonia Overview

PPT1 PLA2G6 ANO3 SLC2A1

4.16e-058281420301334
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS1 THBS2

5.33e-05581230622267
Pubmed

Four Na+/H+ exchanger isoforms are distributed to Golgi and post-Golgi compartments and are involved in organelle pH regulation.

SLC9A7 SLC9A6

5.33e-05581215522866
Pubmed

Derlin-dependent accumulation of integral membrane proteins at cell surfaces.

DERL3 DERL2

5.33e-05581219509052
Pubmed

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

DERL3 DERL2

5.33e-05581216449189
Pubmed

Mustn1 ablation in skeletal muscle results in increased glucose tolerance concomitant with upregulated GLUT expression in male mice.

SLC2A10 SLC2A1

5.33e-05581237170065
Pubmed

Ankyrin-B coordinates the Na/K ATPase, Na/Ca exchanger, and InsP3 receptor in a cardiac T-tubule/SR microdomain.

ANK2 ITPR1

5.33e-05581216292983
Pubmed

Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.

THBS1 THBS2

5.33e-05581223806329
Pubmed

Molecular identification and functional characterization of the vitamin C transporters expressed by Sertoli cells.

SLC23A1 SLC2A1

7.99e-05681218668520
Pubmed

Purkinje cell degeneration associated with erythroid ankyrin deficiency in nb/nb mice.

ANK1 ANK2

7.99e-0568121716634
Pubmed

Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT).

TBC1D1 SLC2A1

7.99e-05681226572137
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1E TRPV6 ITPR1

9.68e-053881330786075
Pubmed

Elucidation of N-glycosylation sites on human platelet proteins: a glycoproteomic approach.

SORT1 THBS1 C9

9.68e-053881316263699
Pubmed

Associations of human erythrocyte band 4.2. Binding to ankyrin and to the cytoplasmic domain of band 3.

ANK1 ANK2

1.12e-0478122968981
Pubmed

Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.

ANK1 ANK2

1.12e-0478127495297
Cytoband5q33.1

SLC36A1 SLC36A3

9.72e-04268125q33.1
Cytoband22q12.3

SLC5A1 SLC5A4

1.57e-033381222q12.3
CytobandEnsembl 112 genes in cytogenetic band chr5p13

PLCXD3 C1QTNF3 C9

1.95e-03139813chr5p13
GeneFamilySolute carriers

SLC25A24 SLC2A10 SLC36A1 SLC16A6 SLC15A4 SLC22A2 SLC9A7 SLC36A3 SLC5A8 SLC35F1 SLC1A1 SLC23A1 SLC9A6 SLC2A1 SLC44A3 SLC5A1 SLC5A4

9.42e-163955417752
GeneFamilyRhomboid family

DERL3 DERL2

7.79e-0414542926
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SLC2A10 THBS1 SLC36A1 TSPAN11 TM9SF4 ENTPD6 DOLK DERL2 PPIL2 CTIF SLC9A6 SLC2A1 UNC50

1.63e-076818113M5314
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

SLC2A10 THBS1 SLC36A1 TSPAN11 TM9SF4 ENTPD6 DOLK DERL2 PPIL2 CTIF SLC9A6 SLC2A1 UNC50

2.34e-077038113MM1055
CoexpressionGSE339_CD4POS_VS_CD8POS_DC_DN

NET1 TXNDC16 CMTM7 UNC50 SLC5A1 ITPR1

3.69e-05200816M5112
CoexpressionGSE27786_NKCELL_VS_NKTCELL_UP

SORT1 SLC15A4 ACLY ATRNL1 TM9SF4 ANO3

3.69e-05200816M4851
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_100

GREB1L SLC22A2 SLC5A8 SLC23A1 SLC5A1

1.07e-0576815gudmap_developingKidney_e15.5_Proximal Tubules_100
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#5_top-relative-expression-ranked_200

SLC22A2 SLC5A8 SLC1A1 SLC5A1

1.97e-0542814gudmap_developingKidney_e15.5_Proximal Tubules_200_k5
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_200

GREB1L SLC22A2 SLC5A8 SLC1A1 SLC23A1 SLC5A1

2.27e-05149816gudmap_developingKidney_e15.5_Proximal Tubules_200
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_1000

GREB1L APH1B TSPAN11 SLC16A6 EHHADH SLC22A2 UMOD MFSD6L SLC5A8 SLC1A1 SLC23A1 SLC5A1

4.02e-057848112gudmap_developingKidney_e15.5_early proxim tubul_1000
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_500

GREB1L SLC16A6 SLC22A2 SLC5A8 SLC35F1 SLC1A1 SLC23A1 SLC5A1

1.18e-04389818gudmap_developingKidney_e15.5_Proximal Tubules_500
CoexpressionAtlasPlasmacytoid, DC.pDC.8+.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3

SORT1 CACNA1E SEC24D NET1 SLC15A4 ATRNL1 SLC9A7 ITPR1

1.67e-04409818GSM605840_500
CoexpressionAtlasPlasmacytoid, DC.pDC.8+.MLN, B220-FITC CD45-APC CD11c-eFluor780 GR1-PE CD8-eFlu, Lymph Node, avg-2

SORT1 CACNA1E SEC24D NET1 SLC15A4 SLC9A7 ADIPOR2 ITPR1

1.70e-04410818GSM854297_500
CoexpressionAtlasPlasmacytoid, DC.pDC.8-.Sp, GR1-PE CD11c-eFluor750 CD8-eFluor480 CD45-APC B220, Spleen, avg-3

SORT1 CACNA1E SEC24D NET1 SLC15A4 ATRNL1 SLC9A7 ITPR1

1.75e-04412818GSM605843_500
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_500

EHHADH SLC22A2 UMOD C1QTNF3 SLC5A8 SLC1A1 SLC23A1 SLC5A1

2.13e-04424818gudmap_kidney_adult_RenalCortexMixed_Std_500
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#5_top-relative-expression-ranked_1000

APH1B SLC22A2 UMOD SLC5A8 SLC1A1 SLC5A1

2.49e-04230816gudmap_developingKidney_e15.5_early proxim tubul_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#3_top-relative-expression-ranked_100

SLC22A2 SLC5A8 SLC5A1

2.69e-0433813gudmap_developingKidney_e15.5_early proxim tubul_100_k3
CoexpressionAtlasB cells, B1b.PC, IgD+ IgM+ CD19+ CD43+ CD5+ CD45R+, Peritoneal Cavity, avg-1

CACNA1E SLC15A4 ATRNL1 SLC9A7 TXNDC16 NIBAN3 ITPR1

2.77e-04332817GSM538230_500
CoexpressionAtlasB cells, B1b.PC, IgD+ IgM+ CD19+ CD43+ CD5- CD45R+, Peritoneal Cavity, avg-2

CACNA1E SLC15A4 ATRNL1 SLC9A7 TXNDC16 NIBAN3 ITPR1

3.03e-04337817GSM538228_500
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 SEC24D THBS1 THBS2 ATRNL1 PLCXD3 ANO3

7.08e-081968173a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 SEC24D THBS1 THBS2 ATRNL1 PLCXD3 ANO3

7.08e-08196817bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHHADH SLC22A2 C1QTNF3 SLC5A8 SLC1A1 SLC23A1

6.38e-07168816b14fd50232887b6dca1f39014d43c6f66e5c3b5c
ToppCellCOVID-19-kidney-Fibroblast-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 ATRNL1 PLCXD3 KAZN ANO3

1.19e-0618781676bfe8c42430a230a8bdf299575c444fb7780f24
ToppCellrenal_papilla_nuclei-Adult_normal_reference|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

SORT1 GREB1L CYP1B1 ANK2 PLCXD3 ITPR1

1.39e-061928166c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCellfacs-Trachea-nan-3m-Epithelial-mucus_secreting_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORT1 GREB1L DERL3 SLC5A8 SLC23A1 SLC44A3

1.43e-061938163038ed3e53d3367136fac5c9773cd5b7414f49d3
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORT1 GREB1L DERL3 SLC5A8 SLC23A1 SLC44A3

1.43e-06193816c5925b3b5d19098e3987789d68a493d7fd548ac9
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORT1 GREB1L DERL3 SLC5A8 SLC23A1 SLC44A3

1.43e-061938166905de261d90dfe3dd2c2cf5b2e26afb2bcc3d5b
ToppCellfacs-Trachea-3m-Epithelial-glandular_epithelial-lung_secretory_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SORT1 GREB1L DERL3 SLC5A8 SLC23A1 SLC44A3

1.43e-06193816f73630725f093c646bdaf178c39505c04a16e2c6
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-pDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC15A4 DERL3 SLC9A7 MFSD6L NIBAN3

3.86e-06129815454bae525f6db3d0dd6347d2a2c3ea9dda9cd212
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHHADH SLC22A2 C1QTNF3 SLC5A8 SLC23A1

1.17e-051628156972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-pDC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

1.17e-05162815f12c08d0d4406f9560ecfc3bc2ff38c3bc58f184
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E DERL3 RXFP2 SLC9A7 NIBAN3

1.28e-0516581536415924d05373e9dd3665be599f4f3f40bf0497
ToppCellfacs-Heart-RA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1E DERL3 RXFP2 SLC9A7 NIBAN3

1.28e-0516581556310fddd3d8e4afdfde066d26cee9747e5b8c6a
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

THBS1 ANK2 TBC1D1 INPPL1 MFSD6L

1.28e-051658155cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHHADH SLC22A2 C1QTNF3 SLC5A8 SLC1A1

1.31e-051668158ab18c9d911eb3a9970bba7a769294b0927538f7
ToppCell367C-Myeloid-Dendritic-pDC|367C / Donor, Lineage, Cell class and subclass (all cells)

SLC15A4 DERL3 SLC9A7 NIBAN3 SLC23A1

1.35e-05167815650de8cd5df070639b8aa292aacead739cfdb02c
ToppCellTuft-tuft-1|World / Class top

SORT1 DCAF6 ANK1 PYCR1 SLC5A1

1.39e-051688158ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

THBS1 ANK2 TBC1D1 INPPL1 MFSD6L

1.39e-05168815327b02f19f4a8607c033203824fdc60a1254331f
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EHHADH SLC22A2 C1QTNF3 SLC5A8 SLC23A1

1.39e-0516881535ce3b2b9c9997d4c101da5949c7271d6a6b8f12
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SEC24D THBS2 ATRNL1 PLCXD3 ANO3

1.43e-05169815a84490724a206c9bbb145f7ce08613f91d100ac4
ToppCelldroplet-Kidney-nan-3m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPR2 EHHADH SLC22A2 SLC5A8 SLC23A1

1.47e-05170815dd48fd3c5c67eb71183981f42975a538f12077c3
ToppCellPND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CYP1B1 SEC24D THBS2 TSPAN11 GAL3ST4

1.74e-0517681508f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E EHHADH SLC22A2 SLC5A8 SLC1A1

1.84e-0517881523a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 ATRNL1 PLCXD3 SLC5A8

1.94e-05180815280ff5c8f292be1b88120db5ff1788b750644856
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 THBS2 ATRNL1 PLCXD3 SLC5A8

1.94e-05180815fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

GREB1L ANK2 PLCXD3 TENM2 SLC5A1

1.99e-05181815719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E EHHADH SLC22A2 SLC5A8 SLC1A1

1.99e-051818156980ea624151da32b7f537f263e40fcb87a02e81
ToppCellwk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CYP1B1 THBS2 TSPAN11 GAL3ST4 ANO3

2.05e-051828150e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 ATRNL1 RXFP2 PLCXD3 ANO3

2.05e-0518281544764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 ATRNL1 RXFP2 PLCXD3 ANO3

2.05e-05182815d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

CERKL SEC24D THBS2 IDE SLC1A1

2.16e-051848159c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1E EHHADH SLC22A2 SLC5A8 SLC1A1

2.16e-05184815dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

GREB1L ANK2 PLCXD3 TENM2 SLC5A1

2.16e-05184815e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1E EHHADH SLC22A2 SLC5A8 SLC1A1

2.21e-051858151bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellLV-15._Ventricular_Cardiomyocyte_III|World / Chamber and Cluster_Paper

GREB1L ANK2 PLCXD3 TENM2 SLC5A1

2.21e-051858156baccb26f999145e51b91d94315bf8d4655bef31
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COX4I1 UMOD ATP5MF SLC5A8 SLC5A1

2.27e-05186815fa5f602f01de5beec529d9f5208172b2914a952d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCAF6 ATRNL1 TENM2 ANO3 ITPR1

2.33e-05187815f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

SLC36A1 EHHADH SLC22A2 SLC5A8 SLC1A1

2.33e-05187815acd305475f3609800af0d7bc68d83ef41228080b
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY TSPAN7 SLC5A8 SLC1A1 SLC5A1

2.39e-051888155b69de5baaac45a6d4daa1dbfcb70a7b2ae744ac
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L CYP1B1 CACNA1E NET1 SLC22A2

2.45e-051898158e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell3'-Airway_Nasal_SMG-Epithelial|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1E NET1 PYCR1 SLC5A8 SLC5A1

2.45e-05189815a174f5757a53a68a753111a204efc1bb6da80d8b
ToppCell3'-Airway_Nasal_SMG|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1E NET1 PYCR1 SLC5A8 SLC5A1

2.45e-05189815bb2b626645e9f060f0d99d05d1ea651fd8bc4945
ToppCellRV-04._Ventricular_Cardiomyocyte_I|RV / Chamber and Cluster_Paper

GREB1L ANK2 PLCXD3 TENM2 SLC5A1

2.45e-051898159c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CACNA1E NET1 PYCR1 SLC5A8 SLC5A1

2.45e-0518981524741fe93438c1031fc5caa8837ef82d8d23f099
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DCAF6 ATRNL1 TENM2 ANO3 ITPR1

2.45e-05189815c3df0e3c50af8f1cfb4d790e668bd7f42b276992
ToppCelldroplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L CYP1B1 CACNA1E NET1 SLC22A2

2.45e-05189815fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TM9SF4 TSPAN7 SLC5A8 SLC1A1 SLC5A1

2.52e-05190815a124e1c12af70161b9ead5d677afa660610444ee
ToppCelldroplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 THBS2 NET1 COX4I1 SLC2A1

2.52e-05190815c1bfc1960a3df49c0f459454a7363804c32418ee
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP1B1 THBS1 THBS2 ANK2 C1QTNF3

2.58e-05191815f5ce33af56178333730be308253943c54a0724cf
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.58e-05191815989bf108c7f2c78dd7f14481570f1819673a5469
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYP1B1 THBS2 TSPAN11 PLCXD3 C1QTNF3

2.58e-0519181524dc77ee8de01b42559f92721655f4281b114e17
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP1B1 THBS2 TSPAN11 PYCR1 C1QTNF3

2.58e-051918159f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.58e-051918153e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.58e-05191815bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellCOVID-19-Lymphoid-pDC|COVID-19 / Condition, Lineage and Cell class

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.58e-0519181525343b11d42128ad16659e5519cd1673266cc505
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-intestinal_crypt_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACLY TSPAN7 SLC5A8 SLC1A1 SLC5A1

2.58e-051918157411b253b16e4d472be0925dee49188f0fd6b0b5
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.65e-05192815d9ff2293358c8b031ba212021012e058014ff472
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class (2021.01.30)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.65e-05192815f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.65e-051928152e8611d65090e39f1a6e74c972288e7b68376d15
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP1B1 THBS1 THBS2 ANK2 C1QTNF3

2.65e-05192815a8b7c539dc3037071bf068f372e4215563e11de4
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP1B1 THBS1 THBS2 ANK2 C1QTNF3

2.65e-051928152143e1fad2e88b90d668e12af37b2092d379090f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EHHADH SLC22A2 SLC5A8 SLC23A1 SLC5A1

2.65e-051928153e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCell3'-Distal_airway-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CYP1B1 THBS1 THBS2 ANK2 C1QTNF3

2.65e-05192815904c003c4f73b1dfc8243cee02aad2676c515e50
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.65e-0519281543569726df281eebe57499e0993b9fd9d36118c2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 PGGHG SLC22A2 SLC5A8 SLC1A1

2.71e-05193815ffa1932da2979d7b63dbac32eb5788346a3f5b2a
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

SORT1 GREB1L ANK2 PLCXD3 TENM2

2.71e-05193815dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A10 SEC24D THBS1 PYCR1 ITPR1

2.71e-051938154aee372ba2c0351b0221d0d468707d1ad21526d6
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NET1 SLC15A4 CYSLTR1 DERL3 NIBAN3

2.71e-0519381530abf991ac17c18679ab7d633e7549c0ce841920
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC2A10 SEC24D THBS1 PYCR1 ITPR1

2.71e-05193815aaa5042388dc451bff384c6bb237348f08280a08
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP1B1 THBS2 TSPAN11 PYCR1 C1QTNF3

2.71e-05193815051f61156b0e2e95292b2d8377faf3190b50f264
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-stromal_related-FDC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CERKL CYP1B1 TSPAN11 ANK2 SLC2A1

2.78e-05194815f9fbb043411546d8c9e0321a64165d411f44aeb7
ToppCellfacs-Trachea-nan-3m-Epithelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L DERL3 SLC5A8 SLC23A1 SLC44A3

2.78e-051948153701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCellfacs-Trachea-nan-3m-Epithelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GREB1L DERL3 SLC5A8 SLC23A1 SLC44A3

2.78e-0519481565f9bf126be26114c2c3f4c46d48318986212a92
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 ATRNL1 PLCXD3 KAZN ANO3

2.78e-05194815cf0244a29934e515446ac917d3c30672b460fb04
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SORT1 KIF20A NET1 EHHADH ADIPOR2

2.78e-05194815effd38e51062b225ecabc7e1c50154e65495d559
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THBS2 ATRNL1 PLCXD3 KAZN ANO3

2.78e-05194815ba7f971fb9a19423602da60770f23d9fead4a451
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEC24D THBS1 THBS2 ATRNL1 ANO3

2.85e-0519581549c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 SEC24D THBS1 ATRNL1 PLCXD3

2.85e-05195815cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SEC24D THBS1 THBS2 ATRNL1 ANO3

2.85e-05195815dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

NET1 SLC15A4 CYSLTR1 DERL3 NIBAN3

2.85e-05195815d8fa96c8f14bd088c3f8bd14f894a2c5b7ad46a7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 SEC24D THBS1 ATRNL1 PLCXD3

2.85e-05195815783bfa8110161cbd6def50ce849cae676c39c458
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.85e-0519581506051de72b5c1e0d483a28b14dabd247dfca0ed9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-pDC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

2.85e-051958153aa44633c72658545aa2b35bf9d532c62f36a451
ToppCellCOVID-19-kidney-Fibroblast-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

THBS1 THBS2 ATRNL1 PLCXD3 KAZN

2.85e-051958153d62ce1c696f47d4d7eb0c5bb0eec2c24b122bb2
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EHHADH SLC22A2 SLC5A8 SLC23A1 SLC5A1

2.92e-051968154ebcaac758ed01d918de9c1cd383a84457b615f3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 THBS1 ATRNL1 PLCXD3 ANO3

2.99e-0519781509946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 THBS1 ATRNL1 KAZN ANO3

2.99e-0519781585a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 THBS2 ATRNL1 PLCXD3 ANO3

2.99e-05197815ae0435f4b4a9cdedb1c201fc56921048390097bf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 THBS1 ATRNL1 KAZN ANO3

2.99e-05197815e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP1B1 THBS2 ATRNL1 PLCXD3 ANO3

2.99e-0519781537f6b6f2809b952382eaebb642b0aad6371f4251
ToppCellControl-Stromal-Fibroblast|Stromal / Disease state, Lineage and Cell class

CYP1B1 THBS2 ANK2 KAZN C9

2.99e-0519781564cc5f61c88e9560b0f8f6f3151255dffb5c3d66
ToppCellCOVID-19-COVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease, condition lineage and cell class

SLC15A4 CYSLTR1 DERL3 SLC9A7 NIBAN3

3.07e-05198815033ed362333e1d33f2aeea8da5865d2228d154dc
ToppCellBiopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

CYP1B1 THBS1 THBS2 ANK2 C1QTNF3

3.22e-052008152c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NET1 ATRNL1 ENTPD6 SLC5A8 SLC5A1

3.22e-05200815030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CYP1B1 THBS2 ANK2 PYCR1 C1QTNF3

3.22e-052008154dbe21cb63569f28c7017cda065ea5ee00d7254e
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-4|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

CYP1B1 THBS2 ANK2 PYCR1 C1QTNF3

3.22e-05200815bde938e5a18844fb8cc1d1be5a086809f7e2b97d
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-4|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CYP1B1 THBS2 ANK2 PYCR1 C1QTNF3

3.22e-052008158256511b099c3eab8e33194f90c9ff354e7cfe8e
ToppCellKidney|World / Skin and Kidney Cells in Lupus Nephritis Patients.

THBS1 ANK2 TBC1D1 SLC22A2 UMOD

3.22e-052008151f99afa1f3c32a2a9cfb4ad33ff4d404e34fac63
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRPV6 PLCXD3 SLC35F1 ANO3

9.32e-0513081405d5a73acf1d7f75a79876b1a06d27c74a89b8a4
Drugsodium

SLC2A10 SLC36A1 ANK2 PPT1 SLC9A7 SLC36A3 ATP5MF TRPV6 SLC5A8 SLC1A1 SLC23A1 SLC9A6 SLC2A1 SLC5A1 SLC5A4

1.04e-069448115CID000000923
DrugGF109203X

CACNA1E THBS1 INPPL1 PLA2G6 PLCXD3 SLC1A1 SLC5A1 ITPR1 SLC5A4

3.45e-06341819CID000002396
Drugalpha-(methylamino)isobutyric acid

SLC36A1 SLC1A1 SLC5A1 SLC5A4

4.35e-0631814CID000075725
DrugCaptopril [62571-86-2]; Up 200; 17.2uM; PC3; HG-U133A

SLC25A24 SLC2A10 THBS1 NET1 ACLY PPIL2 ITPR1

6.83e-061988171907_UP
DrugFludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

GREB1L CYP1B1 SEC24D NPR2 ARSD GAL3ST4 CTIF

6.83e-061988173785_DN
DrugAC1NSPXR

ANK1 ANK2 PLA2G6

7.01e-0611813CID005313815
DrugGleevec; Down 200; 10uM; MCF7; HG-U133A

THBS2 NPR2 ANK2 TSPAN7 GAL3ST4 C1QTNF3 CTIF

7.06e-06199817366_DN
Drughydride

CYP1B1 CACNA1E NPR2 SLC36A1 EHHADH COX4I1 SLC9A7 PYCR1 SLC36A3 ATP5MF SLC1A1 SLC9A6 SLC5A1

7.41e-068358113CID000000783
DrugXeC compound

CACNA1E NPR2 PLA2G6 TRPV6 ITPR1

1.25e-0584815CID000005701
DrugBetaine

SLC36A1 SLC16A6 ACLY COX4I1 CYSLTR1 TSPAN7

2.07e-05157816ctd:D001622
DrugEIPA

CYP1B1 SLC9A7 SLC1A1 SLC23A1 SLC9A6

2.27e-0595815CID000001795
DrugVerteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT_HG-U133A

SORT1 CYP1B1 THBS1 NPR2 TM9SF4 SLC9A6

2.39e-051618163556_DN
Drugindoxyl-beta-D-glucoside

SLC5A8 SLC5A1 SLC5A4

2.85e-0517813CID000092769
DrugIDD594

SORT1 CACNA1E PPT1 SLC5A1

3.02e-0550814CID004369325
Druggentamicin C

SLC2A1 SLC5A1

3.74e-053812ctd:C100093
Drugpotassium

PHAF1 CACNA1E NPR2 PPT1 SLC9A7 SLC36A3 ATP5MF TRPV6 PLCXD3 SLC1A1 SLC9A6 SLC5A1 ITPR1

5.33e-0510088113CID000000813
DrugProbenecid

SLC22A2 UMOD SLC5A8 SLC2A1

5.83e-0559814ctd:D011339
DrugAC1NBU2S

CACNA1E NPR2 CYSLTR1 TRPV6 ITPR1

6.17e-05117815CID004473765
DrugPiperine [94-62-2]; Down 200; 14uM; MCF7; HT_HG-U133A

NPR2 ACLY TBC1D1 TM9SF4 INPPL1 UBA6

6.39e-051928164830_DN
DrugIAA-94

CACNA1E ACLY TRPV6 ITPR1

6.65e-0561814CID000003667
DrugCarbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A

GREB1L SEC24D THBS1 ANK1 PGGHG SLC1A1

6.76e-051948164110_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

SORT1 GREB1L PPIL2 C1QTNF3 CTIF SLC1A1

7.16e-051968164281_UP
DrugMetoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; PC3; HT_HG-U133A

NPR2 GAL3ST4 PLA2G6 PPIL2 C1QTNF3 SLC2A1

7.36e-051978163728_DN
DrugRauwolscine hydrochloride [6211-32-1]; Down 200; 10.2uM; PC3; HT_HG-U133A

SEC24D THBS1 NPR2 SLC9A7 PPIL2 C1QTNF3

7.36e-051978165800_DN
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A

GREB1L CYP1B1 ARSD ANK2 SLC9A7 TRPV6

7.36e-051978164757_UP
DrugAdamantamine fumarate [80789-67-9]; Up 200; 9.6uM; PC3; HT_HG-U133A

ARSD CYSLTR1 SLC22A2 TRPV6 PPIL2 KAZN

7.36e-051978164222_UP
DrugVinpocetine [42971-09-5]; Up 200; 11.4uM; PC3; HT_HG-U133A

SLC36A1 GAL3ST4 PPIL2 C1QTNF3 KAZN SLC2A1

7.36e-051978165859_UP
DrugICI182,780; Down 200; 1uM; PC3; HT_HG-U133A

THBS1 NPR2 PPIL2 C1QTNF3 KAZN SLC5A1

7.36e-051978166867_DN
Drug8-(N,N-diethylamino)octyl-3,4,5-trimethoxybenzoate

CYP1B1 ITPR1

7.47e-054812ctd:C006014
Druglercanidipine

CACNA1E ANK1 TRPV6 ITPR1

7.55e-0563814CID000065866
DrugAspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; PC3; HT_HG-U133A

NPR2 ANK1 SLC9A7 GAL3ST4 SLC1A1 SLC2A1

7.57e-051988164007_UP
DrugPraziquantel [55268-74-1]; Down 200; 12.8uM; HL60; HG-U133A

CYP1B1 APH1B TM9SF4 PLA2G6 IDE SLC2A1

7.57e-051988161572_DN
DrugMethacholine chloride [62-51-1]; Up 200; 20.4uM; MCF7; HT_HG-U133A

SEC24D NPR2 ANK1 TRPV6 PPIL2 CTIF

7.57e-051988166248_UP
DrugMoricizine hydrochloride [31883-05-3]; Up 200; 8.6uM; MCF7; HT_HG-U133A

THBS1 GAL3ST4 PLA2G6 CTIF KAZN SLC1A1

7.78e-051998163520_UP
DrugTheobromine [83-67-0]; Up 200; 22.2uM; PC3; HT_HG-U133A

NPR2 TSPAN7 SLC9A7 C1QTNF3 KAZN SLC2A1

8.00e-052008166613_UP
Drugrofecoxib; Up 200; 10uM; MCF7; HG-U133A

GREB1L NPR2 ANK1 GAL3ST4 PPIL2 KAZN

8.00e-05200816251_UP
DrugT2 D

SLC2A10 COX4I1 IDE SLC2A1 ADIPOR2

9.11e-05127815CID004369452
Drugbumetanide

THBS1 SLC9A7 SLC1A1 SLC9A6 SLC5A1 SLC5A4

1.02e-04209816CID000002471
Drug4 alpha-phorbol 12,13-didecanoate

NPR2 TRPV6 SLC1A1 SLC5A1

1.14e-0470814CID000452543
Drugamicetose

CACNA1E ACLY

1.24e-045812CID000193083
Drug3-O-methyl-D-glucose

SLC2A10 SLC23A1 SLC2A1 SLC5A1

1.27e-0472814CID000008973
DiseaseObesity

CYP1B1 ACLY TBC1D1 SLC22A2 ENTPD6

2.29e-04205795C0028754
Diseasecreatinine measurement, glomerular filtration rate

SORT1 SLC22A2 UMOD C9

2.80e-04117794EFO_0004518, EFO_0005208
Diseaseascorbic acid 3-sulfate measurement

ARSD SLC23A1

6.31e-0414792EFO_0800173
DiseaseDiabetic Angiopathies

THBS1 THBS2

8.29e-0416792C0011875
DiseaseMicroangiopathy, Diabetic

THBS1 THBS2

8.29e-0416792C0025945
Diseasenevus count

CYP1B1 PLA2G6

1.05e-0318792EFO_0004632
Diseasetype 2 diabetes mellitus (is_implicated_in)

INPPL1 IDE SLC2A1 ADIPOR2

1.17e-03171794DOID:9352 (is_implicated_in)
DiseaseHbA1c measurement, response to sulfonylurea

OBP2A OR2Z1

1.44e-0321792EFO_0004541, EFO_0007922
DiseaseNephritis, Tubulointerstitial

THBS1 UMOD

1.44e-0321792C0041349
DiseaseDystonia

CACNA1E ANO3 SLC2A1

1.61e-0386793C0013421
DiseaseNephritis, Interstitial

THBS1 UMOD

1.88e-0324792C0027707
DiseaseMalignant neoplasm of breast

SLC2A10 CYP1B1 THBS1 ANK1 ANK2 NET1 CTIF MSI1 SLC2A1

2.28e-031074799C0006142

Protein segments in the cluster

PeptideGeneStartEntry
GLGFGIMSGVFSFVN

APH1B

121

Q8WW43
GFFSVSARAVTGMAG

ARSD

221

P51689
GFITFLCEVFGTMRS

CTIF

476

O43310
VFALLGMQLFGGRFN

CACNA1E

616

Q15878
TGFLVSFMVDARGGS

ANK1

911

P16157
LGTGITFIMFGVSSF

NPR2

461

P20594
NYAGRGTTGMVARFI

DCAF6

231

Q58WW2
RGRTADFVFMFLFGG

DERL3

91

Q96Q80
LFDNGGTVFFAIFMA

ANO3

466

Q9BYT9
IFGRVVGGFDVLTAM

PPIL2

396

Q13356
VSNLQEFRFMIGGGC

ADIPOR2

366

Q86V24
FGFLGMQSLVFGAQD

NIBAN3

456

Q86XR2
MSVGFIGAGQLAFAL

PYCR1

1

P32322
VRMGGSFRGAFSNSE

NET1

446

Q7Z628
SGFLVSFMVDARGGA

ANK2

966

Q01484
EKMGFGSISRVFARG

KAZN

381

Q674X7
FFERFGIVVAATGMA

DOLK

106

Q9UPQ8
FLMSFVGNCGTFTRG

ITPR1

2376

Q14643
GMIGSFSVGLFVNRF

SLC2A1

76

P11166
LMVFVSAFSFGFGPV

SLC2A10

416

O95528
VVVGNCFGFVGNRML

EHHADH

471

Q08426
LGSFVGGFVVMRFSL

MFSD6L

506

Q8IWD5
GGAAQIFFLTLMGVA

OR2Z1

96

Q8NG97
TFSLSLFGLMGVAFG

MRS2

346

Q9HD23
GTIQILFGIMTFSFG

MS4A5

51

Q9H3V2
AVNFLTGMGGFLQAV

PGGHG

581

Q32M88
ALGGGNLEATFTFMR

OBP2A

56

Q9NY56
RSLGVALGVFMTIGF

GAL3ST4

16

Q96RP7
GMFNNAGVGAARFLI

GREB1L

1571

Q9C091
RGFGFVTFMDQAGVD

MSI1

61

O43347
AMGFSQGGQFLRAVA

PPT1

111

P50897
NFFDVMTGRFGAPVS

C1QTNF3

146

Q9BXJ4
LMRDFSPSGIFGAFQ

ATP5MF

31

P56134
VRTCGFDFGGNIIMF

EIF3I

96

Q13347
AVVINGSMYIFGGFS

ATRNL1

586

Q5VV63
LLRFGFSAMFGFGGR

CERKL

341

Q49MI3
FSAMFGFGGRTLALA

CERKL

346

Q49MI3
VFIMGYSVVAGAAGR

SLC44A3

46

Q8N4M1
ASFRVVSGGRSMAFG

CYP1B1

121

Q16678
GARGFMFFIINVDLT

IDE

366

P14735
RGRTADFVFMFLFGG

DERL2

91

Q9GZP9
KTVVGGAMFFIGFTA

COX4I1

101

P13073
SAIMGLFFFFSGVGS

SLC15A4

486

Q8N697
VNVGFFIGSMSIGYI

SLC22A2

156

O15244
FRTMVNVLGDAFGTG

SLC1A1

446

P43005
MFRSRSIEVFGQFNG

C9

61

P02748
MAIAEVFGRIGAGFV

SLC16A6

336

O15403
FGLGGRFLFASVMAD

SORT1

306

Q99523
SIGIFLGIFSGSFAM

SLC9A6

291

Q92581
FYGIMFDAGSTGTRV

ENTPD6

101

O75354
KGAVGVSFMFNGTSF

INPPL1

541

O15357
AFITCFGNLFVIGMR

RXFP2

426

Q8WXD0
AMLKTNRGTIGGFFL

SLC5A4

46

Q9NY91
FANSIGALVGLMAGF

SLC5A8

436

Q8N695
FFNGRLAGLQRGAMS

TENM2

1896

Q9NT68
MQFFGRLVNTFSGVT

PLA2G6

1

O60733
GSTFCFGLQRMIFEV

PHAF1

381

Q9BSU1
STGFRATDFFGGILM

SEC24D

696

O94855
FFGTAIFTFEGVGMV

SLC36A3

256

Q495N2
ALNGIFVLGRSMGFI

ACLY

1056

P53396
GSFSLLMFFGILGAT

ATRAID

196

Q6UW56
NQSGLVAGAIFGFMA

CMTM7

136

Q96FZ5
SMISVVGFFGNGFVL

CYSLTR1

31

Q9Y271
GMIGLFGAFFSGIQL

SLC35F1

251

Q5T1Q4
TMNFTGQLGAGIRYF

PLCXD3

81

Q63HM9
TGQFLTFREINGMTG

UBA6

241

A0AVT1
MFSGFNVFRVGISFV

TXNDC16

1

Q9P2K2
TIGFGFVLDMGFFET

UNC50

96

Q53HI1
GRLGLFVFSQEMVFF

THBS1

1146

P07996
GESSQGRFSVQMFRF

UMOD

541

P07911
FMFMGVFGGFSAGRL

TM9SF4

386

Q92544
FFGTAIFSFEGIGMV

SLC36A1

261

Q7Z2H8
RNLFVLGFSMFFGLT

SLC23A1

456

Q9UHI7
RVFQGFFTGRGRSCM

KIF20A

466

O95235
GFVARVFDMIFLQGT

TBC1D1

981

Q86TI0
DIFRMGVTRFFGQTI

TRPV6

446

Q9H1D0
FAGVLVMVTGFLGFG

TSPAN11

66

A1L157
AGGRLGLFVFSQEMV

THBS2

1146

P35442
IFLGIFSGSFTMGAV

SLC9A7

326

Q96T83
AMFSTNRGTVGGFFL

SLC5A1

46

P13866
TNMGIIAGVAFGIAF

TSPAN7

211

P41732
IGTFERFISGSMAGA

SLC25A24

286

Q6NUK1