Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ABC-type bile acid transporter activity	ABCC3 ABCC4	7.66e-05	4	72	2	GO:0015432
GeneOntologyMolecularFunction	ATPase-coupled organic acid transmembrane transporter activity	ABCC3 ABCC4	7.66e-05	4	72	2	GO:0033283
GeneOntologyMolecularFunction	ATPase-coupled monocarboxylic acid transmembrane transporter activity	ABCC3 ABCC4	7.66e-05	4	72	2	GO:0033285
GeneOntologyMolecularFunction	ATPase-coupled carboxylic acid transmembrane transporter activity	ABCC3 ABCC4	7.66e-05	4	72	2	GO:0033284
GeneOntologyMolecularFunction	ABC-type glutathione S-conjugate transporter activity	ABCC3 ABCC4	3.54e-04	8	72	2	GO:0015431
GeneOntologyMolecularFunction	ATPase-coupled lipid transmembrane transporter activity	ABCC3 ABCC4	4.54e-04	9	72	2	GO:0034040
GeneOntologyMolecularFunction	ATPase-coupled inorganic anion transmembrane transporter activity	ABCC3 ABCC4	5.66e-04	10	72	2	GO:0043225
GeneOntologyMolecularFunction	icosanoid transmembrane transporter activity	ABCC3 ABCC4	1.31e-03	15	72	2	GO:0071714
GeneOntologyMolecularFunction	transmembrane-ephrin receptor activity	EPHB2 EPHB6	1.31e-03	15	72	2	GO:0005005
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC3 ABCC4	1.31e-03	15	72	2	GO:0008559
GeneOntologyMolecularFunction	organic hydroxy compound transmembrane transporter activity	SLC6A2 ABCC3 ABCC4	2.07e-03	70	72	3	GO:1901618
GeneOntologyMolecularFunction	ephrin receptor activity	EPHB2 EPHB6	2.11e-03	19	72	2	GO:0005003
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC6A2 SLC29A2	2.58e-03	21	72	2	GO:0005326
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC30A7 SLC39A1	3.36e-03	24	72	2	GO:0005385
GeneOntologyMolecularFunction	transmembrane receptor protein kinase activity	EPHB2 EPHB6 ACVR2A	3.59e-03	85	72	3	GO:0019199
GeneOntologyMolecularFunction	cullin family protein binding	GMCL2 KCTD21	3.94e-03	26	72	2	GO:0097602
Domain	Ephrin_rec_like	EPHB2 EPHB6	7.45e-04	11	70	2	PF07699
Domain	RECEPTOR_TYR_KIN_V_2	EPHB2 EPHB6	1.22e-03	14	70	2	PS00791
Domain	RECEPTOR_TYR_KIN_V_1	EPHB2 EPHB6	1.22e-03	14	70	2	PS00790
Domain	Eph_TM	EPHB2 EPHB6	1.22e-03	14	70	2	IPR027936
Domain	Tyr_kinase_rcpt_V_CS	EPHB2 EPHB6	1.22e-03	14	70	2	IPR001426
Domain	EPH_lbd	EPHB2 EPHB6	1.22e-03	14	70	2	SM00615
Domain	Ephrin_lbd	EPHB2 EPHB6	1.22e-03	14	70	2	PF01404
Domain	EphA2_TM	EPHB2 EPHB6	1.22e-03	14	70	2	PF14575
Domain	Tyr_kinase_ephrin_rcpt	EPHB2 EPHB6	1.22e-03	14	70	2	IPR016257
Domain	Ephrin_rcpt_lig-bd_dom	EPHB2 EPHB6	1.22e-03	14	70	2	IPR001090
Domain	EPH_LBD	EPHB2 EPHB6	1.22e-03	14	70	2	PS51550
Domain	-	EPHB2 EPHB6 DCBLD1	2.60e-03	73	70	3	2.60.120.260
Domain	ABC_membrane	ABCC3 ABCC4	3.62e-03	24	70	2	PF00664
Domain	Ephrin_rec_like	EPHB2 EPHB6	3.93e-03	25	70	2	SM01411
Domain	Tyr-kin_ephrin_A/B_rcpt-like	EPHB2 EPHB6	3.93e-03	25	70	2	IPR011641
Domain	SAM	EPHB2 EPHB6 TNKS	4.41e-03	88	70	3	SM00454
Domain	BTB	GMCL1 GMCL2 KCND2 KCTD21	4.66e-03	180	70	4	SM00225
Domain	ABC_TM1F	ABCC3 ABCC4	4.91e-03	28	70	2	PS50929
Domain	ABC1_TM_dom	ABCC3 ABCC4	4.91e-03	28	70	2	IPR011527
Domain	BTB/POZ_dom	GMCL1 GMCL2 KCND2 KCTD21	5.14e-03	185	70	4	IPR000210
Domain	Galactose-bd-like	EPHB2 EPHB6 DCBLD1	5.30e-03	94	70	3	IPR008979
Domain	SAM_DOMAIN	EPHB2 EPHB6 TNKS	5.46e-03	95	70	3	PS50105
Domain	SAM	EPHB2 EPHB6 TNKS	5.78e-03	97	70	3	IPR001660
Domain	GPS	ADGRG5 ADGRE1	7.19e-03	34	70	2	SM00303
Domain	-	EPHB2 EPHB6 TNKS	7.38e-03	106	70	3	1.10.150.50
Pathway	REACTOME_AZATHIOPRINE_ADME	ABCC4 XDH SLC29A2	7.96e-05	23	52	3	M45013
Pathway	REACTOME_AZATHIOPRINE_ADME	ABCC4 XDH SLC29A2	1.30e-04	27	52	3	MM15693
Pubmed	Mouse germ cell-less as an essential component for nuclear integrity.	GMCL1 GMCL2	4.23e-06	2	72	2	12556490
Pubmed	Oral availability of cefadroxil depends on ABCC3 and ABCC4.	ABCC3 ABCC4	4.23e-06	2	72	2	22166395
Pubmed	Molecular cloning and genomic organization of mouse homologue of Drosophila germ cell-less and its expression in germ lineage cells.	GMCL1 GMCL2	4.23e-06	2	72	2	10448096
Pubmed	Stage-specific expression of mouse germ cell-less-1 (mGCL-1), and multiple deformations during mgcl-1 deficient spermatogenesis leading to reduced fertility.	GMCL1 GMCL2	4.23e-06	2	72	2	15700541
Pubmed	Identification of Neurochondrin as a new interaction partner of the FH3 domain of the Diaphanous-related formin Dia1.	DIAPH1 NCDN	4.23e-06	2	72	2	18572016
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	SLC30A7 ABCC4 SV2A TMEM43 VPS16 RABL3 YME1L1 SH3BP4	9.77e-06	504	72	8	34432599
Pubmed	Hepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.	ABCC3 ABCC4	1.27e-05	3	72	2	25952649
Pubmed	A genome-wide association study of survival in small-cell lung cancer patients treated with irinotecan plus cisplatin chemotherapy.	ABCC4 DCBLD1	1.27e-05	3	72	2	23478653
Pubmed	Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.	ABCC3 ABCC4	1.27e-05	3	72	2	15886284
Pubmed	Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.	ABCC3 ABCC4	1.27e-05	3	72	2	19480556
Pubmed	Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5, homologues of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines.	ABCC3 ABCC4	1.27e-05	3	72	2	9270026
Pubmed	A Phase II trial of gemcitabine and mitoxantrone for patients with acute myeloid leukemia in first relapse.	ABCC4 SLC29A2	1.27e-05	3	72	2	21156465
Pubmed	Targeting of the mouse Slc39a2 (Zip2) gene reveals highly cell-specific patterns of expression, and unique functions in zinc, iron, and calcium homeostasis.	SLC39A1 ADGRE1	1.27e-05	3	72	2	17506078
Pubmed	ABCC multidrug transporters in childhood neuroblastoma: clinical and biological effects independent of cytotoxic drug efflux.	ABCC3 ABCC4	1.27e-05	3	72	2	21799180
Pubmed	ATP-binding cassette C transporters in human pancreatic carcinoma cell lines. Upregulation in 5-fluorouracil-resistant cells.	ABCC3 ABCC4	1.27e-05	3	72	2	19077464
Pubmed	Multidrug resistance proteins 2 and 3 provide alternative routes for hepatic excretion of morphine-glucuronides.	ABCC3 ABCC4	1.27e-05	3	72	2	17485564
Pubmed	Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.	ABCC3 ABCC4	1.27e-05	3	72	2	17273943
Pubmed	Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.	GMCL1 GMCL2	1.27e-05	3	72	2	9878064
Pubmed	A paradigm shift in EPH receptor interaction: biological relevance of EPHB6 interaction with EPHA2 and EPHB2 in breast carcinoma cell lines.	EPHB2 EPHB6	2.53e-05	4	72	2	21737611
Pubmed	Enhanced degradation of MDM2 by a nuclear envelope component, mouse germ cell-less.	GMCL1 GMCL2	2.53e-05	4	72	2	12927808
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EPHB2 SLC30A7 ABCC3 TCTN3 ABCC4 SLC39A1 UGGT1 PRDX3 NAGA DCBLD1 TMEM43	3.49e-05	1201	72	11	35696571
Pubmed	Efflux protein expression in human stem cell-derived retinal pigment epithelial cells.	ABCC3 ABCC4	4.21e-05	5	72	2	22272278
Pubmed	Identification of a mouse germ cell-less homologue with conserved activity in Drosophila.	GMCL1 GMCL2	6.31e-05	6	72	2	10727854
Pubmed	Identification and characterization of a seven transmembrane hormone receptor using differential display.	XDH ADGRE1	6.31e-05	6	72	2	9169125
Pubmed	Molecular characterization of mammalian homologues of class C Vps proteins that interact with syntaxin-7.	TNKS VPS16	6.31e-05	6	72	2	11382755
Pubmed	Association of multi-drug resistance gene polymorphisms with pancreatic cancer outcome.	ABCC3 ABCC4	8.82e-05	7	72	2	20922799
Pubmed	EphB3 marks delaminating endocrine progenitor cells in the developing pancreas.	EPHB2 EPHB6	1.17e-04	8	72	2	22434763
Pubmed	Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.	ABCC3 ABCC4	1.17e-04	8	72	2	15802388
Pubmed	EphB/syndecan-2 signaling in dendritic spine morphogenesis.	EPHB2 EPHB6	1.51e-04	9	72	2	11580899
Pubmed	PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor.	EPHB2 EPHB6	1.51e-04	9	72	2	9707552
Pubmed	Establishment and Dysfunction of the Blood-Brain Barrier.	ABCC3 ABCC4 SLC29A2	1.75e-04	52	72	3	26590417
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	EHBP1 ABCC3 PIEZO2 NRK DCBLD1 RABL3 SLC29A2	1.78e-04	569	72	7	30639242
Pubmed	EphB signaling regulates target innervation in the developing and deafferented auditory brainstem.	EPHB2 EPHB6	1.88e-04	10	72	2	22021100
Pubmed	EphB2 guides axons at the midline and is necessary for normal vestibular function.	EPHB2 EPHB6	1.88e-04	10	72	2	10839360
Pubmed	Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons.	EPHB2 EPHB6	1.88e-04	10	72	2	11493560
Pubmed	Overview of mammalian zinc transporters.	SLC30A7 SLC39A1	2.30e-04	11	72	2	14704853
Pubmed	Nuclear membrane protein LAP2beta mediates transcriptional repression alone and together with its binding partner GCL (germ-cell-less).	GMCL1 GMCL2	2.75e-04	12	72	2	11591818
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	SMG1 ABCC3 WDR86 RABL3 YME1L1 DSN1 ZNF568	3.55e-04	638	72	7	31182584
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SLC6A2 C5orf63 UGGT1 RXFP2 DIAPH1 ACVR2A PLP2 ZNF568 NCDN	3.93e-04	1084	72	9	11544199
Pubmed	Mutations that affect meiosis in male mice influence the dynamics of the mid-preleptotene and bouquet stages.	GMCL1 GMCL2	4.36e-04	15	72	2	17010969
Pubmed	USP25 regulates Wnt signaling by controlling the stability of tankyrases.	UGGT1 TNKS	4.98e-04	16	72	2	28619731
Pubmed	Ephrin-B2 and EphB1 mediate retinal axon divergence at the optic chiasm.	EPHB2 EPHB6	5.63e-04	17	72	2	12971893
Pubmed	Disruption of segmental neural crest migration and ephrin expression in delta-1 null mice.	EPHB2 EPHB6	5.63e-04	17	72	2	12217323
Pubmed	Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.	EHBP1 RANGAP1 PDE3A RABL3	6.77e-04	191	72	4	31177093
Pubmed	Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.	UGGT1 PRDX3 DIAPH1 VPS16 MTX1 YME1L1	7.00e-04	515	72	6	31617661
Pubmed	Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis.	EPHB2 ADGRE1	7.06e-04	19	72	2	28017833
Pubmed	Expression of Ephs and ephrins in developing mouse inner ear.	EPHB2 EPHB6	7.06e-04	19	72	2	12684176
Pubmed	Loss of RPS27a expression regulates the cell cycle, apoptosis, and proliferation via the RPL11-MDM2-p53 pathway in lung adenocarcinoma cells.	PRDX3 PLP2	7.06e-04	19	72	2	35073964
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	ABCC4 GLS2 ACVR2A	7.19e-04	84	72	3	15123239
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	EHBP1 SMG1 ABCC3 TCTN3 ABCC4 OASL TMEM43	7.21e-04	719	72	7	35337019
Pubmed	Eph receptors and ephrins: effectors of morphogenesis.	EPHB2 EPHB6	7.84e-04	20	72	2	10207129
Pubmed	Multiple roles of EPH receptors and ephrins in neural development.	EPHB2 EPHB6	7.84e-04	20	72	2	11256076
Pubmed	The Eph family receptors and ligands.	EPHB2 EPHB6	7.84e-04	20	72	2	9576626
Pubmed	The ephrins and Eph receptors in neural development.	EPHB2 EPHB6	7.84e-04	20	72	2	9530499
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	EPHB2 SLC30A7 RAB35 RANGAP1 SV2A TNKS TMEM43 MTX1 PLP2	8.28e-04	1203	72	9	29180619
Pubmed	Unified nomenclature for Eph family receptors and their ligands, the ephrins. Eph Nomenclature Committee.	EPHB2 EPHB6	8.65e-04	21	72	2	9267020
Pubmed	PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.	PDE3A KCND2	8.65e-04	21	72	2	39304345
Pubmed	Developmental expression of Eph and ephrin family genes in mammalian small intestine.	EPHB2 EPHB6	8.65e-04	21	72	2	20112066
Pubmed	Eph receptors and ephrins demarcate cerebellar lobules before and during their formation.	EPHB2 EPHB6	8.65e-04	21	72	2	10495276
Pubmed	Roles of Eph receptors and ephrins in segmental patterning.	EPHB2 EPHB6	8.65e-04	21	72	2	11128993
Pubmed	Eph receptors and ephrins: regulators of guidance and assembly.	EPHB2 EPHB6	8.65e-04	21	72	2	10730216
Pubmed	Hippo signaling regulates differentiation and maintenance in the exocrine pancreas.	RBPJL ADGRE1	9.50e-04	22	72	2	23454691
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCC3 ABCC4	9.50e-04	22	72	2	8894702
Pubmed	Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia.	PRDX3 ADGRE1	9.50e-04	22	72	2	28432216
Pubmed	Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis.	EPHB2 EPHB6	1.04e-03	23	72	2	19571816
Pubmed	Promotion of proliferation in the developing cerebral cortex by EphA4 forward signaling.	EPHB2 EPHB6	1.04e-03	23	72	2	19542359
Pubmed	APJ Regulates Parallel Alignment of Arteries and Veins in the Skin.	EPHB2 ADGRE1	1.04e-03	23	72	2	25920569
Pubmed	Eph receptors and their ephrin ligands are expressed in developing mouse pancreas.	EPHB2 EPHB6	1.13e-03	24	72	2	16446123
Pubmed	Peroxisome Metabolism Contributes to PIEZO2-Mediated Mechanical Allodynia.	PIEZO2 KCND2	1.23e-03	25	72	2	35681537
Pubmed	A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.	SLC30A7 SLC39A1 UGGT1 TM7SF3 TMEM43	1.34e-03	392	72	5	33144569
Pubmed	Blood-Brain Barrier: From Physiology to Disease and Back.	ABCC3 ABCC4 SLC29A2	1.37e-03	105	72	3	30280653
Pubmed	Replication of a genome-wide case-control study of esophageal squamous cell carcinoma.	XDH EPG5	1.43e-03	27	72	2	18649358
Pubmed	5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia.	SMG1 NCDN	1.43e-03	27	72	2	23027611
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	EPHB2 TCTN3 TMEM168 VPS16 ACVR2A MTX1 RABL3 PLP2	1.56e-03	1061	72	8	33845483
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRG5 ADGRE1	1.65e-03	29	72	2	15203201
Pubmed	Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.	ABCC3 ABCC4	1.77e-03	30	72	2	20200426
Pubmed	Senescence is a developmental mechanism that contributes to embryonic growth and patterning.	EPHB2 ADGRE1	1.77e-03	30	72	2	24238961
Pubmed	Identification of Zika Virus and Dengue Virus Dependency Factors using Functional Genomics.	RANGAP1 UGGT1 PRDX3 TMEM43 YME1L1	1.85e-03	422	72	5	27342126
Pubmed	PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.	EPHB2 EPHB6 DCBLD1	1.87e-03	117	72	3	17145500
Pubmed	miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network.	KCND2 SV2A	1.89e-03	31	72	2	37816598
Pubmed	Identifying protein partners of CLN8, an ER-resident protein involved in neuronal ceroid lipofuscinosis.	MTX1 PLP2	1.89e-03	31	72	2	23142642
Pubmed	Negative regulation of EGFR signalling by the human folliculin tumour suppressor protein.	RAB35 RABL3	2.01e-03	32	72	2	28656962
GeneFamily	ATP binding cassette subfamily C	ABCC3 ABCC4	3.31e-04	13	38	2	807
GeneFamily	Fibronectin type III domain containing\|Sterile alpha motif domain containing\|EPH receptors	EPHB2 EPHB6	3.85e-04	14	38	2	1095
GeneFamily	Sterile alpha motif domain containing	EPHB2 EPHB6 TNKS	8.31e-04	88	38	3	760
GeneFamily	Solute carriers	SLC30A7 SLC6A2 SLC39A1 SLC29A2	9.22e-03	395	38	4	752
Drug	1-naphthylglucuronide	ABCC3 ABCC4 YME1L1	6.02e-07	6	72	3	CID000114851
Drug	Apa-sg	ABCC3 ABCC4 YME1L1	2.83e-05	19	72	3	CID000126348
Drug	harmol glucuronide	ABCC3 ABCC4	2.95e-05	3	72	2	CID005488285
Drug	E3040 sulfate	ABCC3 YME1L1	2.95e-05	3	72	2	CID000443293
Drug	Aminopurine, 6-benzyl [1214-39-7]; Down 200; 17.8uM; MCF7; HT_HG-U133A	EPHB2 RANGAP1 PRDX3 TM7SF3 OASL NCDN	3.57e-05	195	72	6	4748_DN
Drug	Ribostamycin sulfate salt [53797-35-6]; Up 200; 7.2uM; PC3; HT_HG-U133A	ABCC3 RANGAP1 ENTPD1 NAGA DIAPH1 SLC29A2	3.67e-05	196	72	6	7123_UP
Drug	Pyrantel tartrate [33401-94-4]; Down 200; 11.2uM; MCF7; HT_HG-U133A	EPHB2 EHBP1 PRDX3 ENTPD1 OASL XDH	3.78e-05	197	72	6	2260_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Up 200; 19.6uM; MCF7; HT_HG-U133A	EPHB2 RAB35 RANGAP1 GLS2 OASL XDH	3.89e-05	198	72	6	7023_UP
Drug	Dropropizine (R,S) [17692-31-8]; Up 200; 17uM; MCF7; HT_HG-U133A	RAB35 ABCC4 GLS2 ENTPD1 XDH ACVR2A	4.00e-05	199	72	6	7429_UP
Drug	6-methylpurine-2'-deoxyriboside	SLC6A2 ABCC3 ABCC4 SLC29A2	4.19e-05	61	72	4	CID000097184
Drug	hydroxyrubicin	ABCC3 ABCC4 XDH	5.13e-05	23	72	3	CID000072398
Disease	Sudden Cardiac Arrest	KCND2 TMEM43	1.50e-04	8	69	2	C1720824
Disease	cholestasis (biomarker_via_orthology)	ABCC3 ABCC4 XDH	2.09e-04	49	69	3	DOID:13580 (biomarker_via_orthology)
Disease	Marfan syndrome (implicated_via_orthology)	MUS81 ACVR2A	2.40e-04	10	69	2	DOID:14323 (implicated_via_orthology)
Disease	response to irinotecan	ABCC4 DCBLD1	5.55e-04	15	69	2	EFO_0004829
Disease	triiodothyronine measurement	EPHB2 AGBL1	6.33e-04	16	69	2	EFO_0008392
Disease	X-12063 measurement	GMCL1 SV2A AGBL1 EPG5	9.60e-04	186	69	4	EFO_0021283
Disease	Ischemic stroke	SLC6A2 PDE3A RXFP2 AGBL1 EPG5	9.79e-04	324	69	5	HP_0002140
Disease	carotid plaque build	KCND2 WDR86 EPG5	1.02e-03	84	69	3	EFO_0006501
Disease	Infiltrating duct carcinoma of female breast	SMG1 NRK	1.10e-03	21	69	2	C3165106
Disease	platelet crit	ADGRG5 GMCL2 ABCC4 ENTPD1 ARHGAP25 RP1 EPG5 SH3BP4	1.67e-03	952	69	8	EFO_0007985
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	SLC6A2 ADGRE1	1.96e-03	28	69	2	DOID:1094 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSFSTLLGFLQASRK	PNAS-138	6	Q9BZS9
LARSSFGLFLRNCSA	C5orf63	11	A6NC05
FGLFLRNCSASKTTL	C5orf63	16	A6NC05
LISTLGVFALNCFTK	C21orf62	11	Q9NYP8
LKNSRLCSLLSPFFT	EPG5	1721	Q9HCE0
NLFVYSSSKGSLRLC	PPP2R2C	236	Q9Y2T4
KLAFAVFLISCSSGA	ACVR2A	6	P27037
AFLSSKTRCKFFSLT	CASTOR2	31	A6NHX0
ETSKFTRSSFGSCLI	C8orf89	11	P0DMQ9
AFGFNISFLCKLRDT	DIAPH1	996	O60610
SNCLRFFSKFESGNL	AGBL1	591	Q96MI9
LRLASFDSSGKLICS	GMCL1	456	Q96IK5
GFEALLKSSACFTLQ	RANGAP1	131	P46060
DLCISSGSKVSLFNR	RBPJL	206	Q9UBG7
KSSLLLRFADNTFSG	RAB35	21	Q15286
LAAGSSNAVKLSRFF	RABL3	186	Q5HYI8
TFGSSFLISACFKLI	ABCC3	306	O15438
LSKTKAISFSGCFLQ	OR11H4	96	Q8NGC9
SFSPSLLKIFCQLFS	KIAA0100	121	Q14667
ANIFSTSCLFLKLLG	KCTD21	146	Q4G0X4
SSGSKFLALLVNLAC	NCDN	301	Q9UBB6
SNLVCKVSDFGLSRF	EPHB2	756	P29323
LVTFTFLSAKCLQGN	PCDHGC5	706	Q9Y5F6
LSSALCAGSLSFLLA	PDE3A	61	Q14432
TLKSCASELGFLLFS	KCND2	316	Q9NZV8
RGTSFCQKLVSLFNF	GLS2	446	Q9UI32
RISSSQGRLKAFSTC	OR9G9	226	P0C7N8
TFCSKNILAILGFSS	ENTPD1	11	P49961
QRLSSLTFGCFLSRA	PLEKHH2	186	Q8IVE3
GLVIRKFLNSSEFCS	PAQR9	361	Q6ZVX9
CTNFSRTRKGILLFA	PLP2	16	Q04941
LLSSRCSLAKYGIFS	OASL	406	Q15646
QSCFGKLFSSLRSKT	ABCC4	251	O15439
LFCLAVLAASSFSKA	C17orf99	6	Q6UX52
GYCSFSKSRILNTLL	CARD6	461	Q9BX69
FFCGLLILSSIQDKS	CASD1	781	Q96PB1
SKRLGCLLLSSFQFS	DSN1	131	Q9H410
QFSLSCIFLREGKAT	EHBP1	151	Q8NDI1
KRFLFTSNGCSRSLS	DCBLD1	246	Q8N8Z6
RSSGLKLAACSFSAD	RP1	376	P56715
LQFPSTLGRCKAFST	OR10K2	226	Q6IF99
CLTLLSQRLGSQKFF	MTX1	326	Q13505
CTRGDKLFFTSTLRN	NRK	1546	Q7Z2Y5
FSTFLLALFCITKGG	SLC6A2	451	P23975
IGLKAFAFCVATSLT	TMEM43	346	Q9BTV4
GLSCGASLSFLFKAL	SLC29A2	441	Q14542
FSKSTVGLQCLRSDS	SH3BP4	406	Q9P0V3
AAFAGLTTLCLVKTF	LMBR1L	441	Q6UX01
KFGLCTFSDVAQLSL	EPHB6	971	O15197
LRLASFDSSGKLVCS	GMCL2	456	Q8NEA9
TFTLFKCLLLTGGCT	PTCHD4	781	Q6ZW05
EFFRLCGTFSKTLSG	SMG1	3031	Q96Q15
TLKNCSSFLLALLAF	SPPL2C	371	Q8IUH8
GNRIKYLTNSTFLSC	RXFP2	266	Q8WXD0
RQIGCFSLFKTLASL	SLC26A10	176	Q8NG04
TNLLCSGSSQAKLFS	PRDX3	41	P30048
KRTTAFGFLNALCKL	SV2A	681	Q7L0J3
LTFKAFAQLFILGCS	ADGRE1	796	Q14246
LAFKLSCDFSGLSLT	ADGRG5	76	Q8IZF4
NECGKAFSRISSLTL	ZNF568	561	Q3ZCX4
FLRGSFKSSCVSLTL	STKLD1	296	Q8NE28
GSASRQKALSLVSCF	SLC39A1	61	Q9NY26
RKCFLTSAFQGANSS	ARHGAP25	446	P42331
FCRVTLGKSFLQFST	TNKS	1251	O95271
QKSLLRAASFGKCFL	VPS16	396	Q9H269
TGRLLKSLCFISLSF	PIEZO2	56	Q9H5I5
LLFFGSQASRCSAQK	SERPINI2	11	O75830
LCKTNLPSNTAFRGF	XDH	901	P47989
FLLGLLCFLDNSSFK	TMEM168	101	Q9H0V1
SDKTSRNLFFFLCLN	SLC30A7	31	Q8NEW0
KYGNLDIFSTLRSSC	YME1L1	166	Q96TA2
TRFFKNLASSCTLDS	TCTN3	256	Q6NUS6
RSLSRLFSNKVGCAA	WDR86	356	Q86TI4
NLFKFCLSLRSYSAT	UGGT1	116	Q9NYU2
CASLGRVSSKVFFTL	TM7SF3	286	Q9NS93
LSNKASALVFFSCRT	NAGA	331	P17050
CSLLTFSDFNAGAIK	MUS81	451	Q96NY9