Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	KIF21B SEPTIN8 RHOH MYO1E DHX37 RAB43 ABCC11 CCT4 DHX35 DDX20 DDX43 NKIRAS2 SEPTIN10 KIF13A DNA2 ATP13A2 ABCB1 RAB33B	4.20e-09	775	86	18	GO:0017111
GeneOntologyMolecularFunction	ATP-dependent activity	MYO1G KIF21B MYO1A MYO1D MYO1E DHX37 ABCC11 CCT4 DHX35 DDX20 DDX43 KIF13A DNA2 ATP13A2 DICER1 ABCB1	6.91e-09	614	86	16	GO:0140657
GeneOntologyMolecularFunction	pyrophosphatase activity	KIF21B SEPTIN8 RHOH MYO1E DHX37 RAB43 ABCC11 CCT4 DHX35 DDX20 DDX43 NKIRAS2 SEPTIN10 KIF13A DNA2 ATP13A2 ABCB1 RAB33B	1.44e-08	839	86	18	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	KIF21B SEPTIN8 RHOH MYO1E DHX37 RAB43 ABCC11 CCT4 DHX35 DDX20 DDX43 NKIRAS2 SEPTIN10 KIF13A DNA2 ATP13A2 ABCB1 RAB33B	1.46e-08	840	86	18	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	KIF21B SEPTIN8 RHOH MYO1E DHX37 RAB43 ABCC11 CCT4 DHX35 DDX20 DDX43 NKIRAS2 SEPTIN10 KIF13A DNA2 ATP13A2 ABCB1 RAB33B	1.46e-08	840	86	18	GO:0016818
GeneOntologyMolecularFunction	ATP hydrolysis activity	KIF21B MYO1E DHX37 ABCC11 CCT4 DHX35 DDX20 DDX43 KIF13A DNA2 ATP13A2 ABCB1	4.05e-07	441	86	12	GO:0016887
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1G KIF21B MYO1A MYO1D MYO1E KIF13A	1.20e-05	118	86	6	GO:0003774
GeneOntologyMolecularFunction	microfilament motor activity	MYO1G MYO1A MYO1D MYO1E	2.12e-05	38	86	4	GO:0000146
GeneOntologyMolecularFunction	calmodulin binding	MYO1G SLC8A1 MYO1A MYO1D MYO1E OBSCN KCNQ1	6.09e-05	230	86	7	GO:0005516
GeneOntologyMolecularFunction	helicase activity	DHX37 DHX35 DDX20 DDX43 DNA2 DICER1	6.23e-05	158	86	6	GO:0004386
GeneOntologyMolecularFunction	RNA helicase activity	DHX37 DHX35 DDX20 DDX43	3.59e-04	78	86	4	GO:0003724
GeneOntologyMolecularFunction	ATP-dependent activity, acting on RNA	DHX37 DHX35 DDX20 DDX43	3.95e-04	80	86	4	GO:0008186
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC11 ATP13A2 ABCB1	1.23e-03	49	86	3	GO:0140359
GeneOntologyMolecularFunction	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	DNA2 DICER1	1.61e-03	14	86	2	GO:0016888
GeneOntologyMolecularFunction	ABC-type xenobiotic transporter activity	ABCC11 ABCB1	1.86e-03	15	86	2	GO:0008559
GeneOntologyMolecularFunction	phosphatidylinositol bisphosphate binding	MYO1G OBSCN KCNQ1 ATP13A2	1.86e-03	121	86	4	GO:1902936
GeneOntologyCellularComponent	myosin complex	MYO1G MYO1A MYO1D MYO1E	1.02e-04	59	86	4	GO:0016459
Domain	P-loop_NTPase	MYO1G KIF21B SEPTIN8 RHOH MYO1A MYO1D MYO1E DHX37 RAB43 ABCC11 DHX35 DDX20 DDX43 NKIRAS2 SEPTIN10 KIF13A DNA2 DICER1 ABCB1 RAB33B	1.19e-09	848	86	20	IPR027417
Domain	Myosin_TH1	MYO1G MYO1A MYO1D MYO1E	1.45e-08	7	86	4	PF06017
Domain	Myosin_TH1	MYO1G MYO1A MYO1D MYO1E	1.45e-08	7	86	4	IPR010926
Domain	TH1	MYO1G MYO1A MYO1D MYO1E	1.45e-08	7	86	4	PS51757
Domain	-	SEPTIN8 RHOH MYO1E DHX37 RAB43 ABCC11 DHX35 DDX20 DDX43 NKIRAS2 SEPTIN10 DNA2 DICER1 ABCB1 RAB33B	1.42e-06	746	86	15	3.40.50.300
Domain	DEAD/DEAH_box_helicase_dom	DHX37 DHX35 DDX20 DDX43 DICER1	2.16e-05	73	86	5	IPR011545
Domain	DEAD	DHX37 DHX35 DDX20 DDX43 DICER1	2.16e-05	73	86	5	PF00270
Domain	Myosin_head_motor_dom	MYO1G MYO1A MYO1D MYO1E	2.74e-05	38	86	4	IPR001609
Domain	MYOSIN_MOTOR	MYO1G MYO1A MYO1D MYO1E	2.74e-05	38	86	4	PS51456
Domain	Myosin_head	MYO1G MYO1A MYO1D MYO1E	2.74e-05	38	86	4	PF00063
Domain	MYSc	MYO1G MYO1A MYO1D MYO1E	2.74e-05	38	86	4	SM00242
Domain	Helicase_C	DHX37 DHX35 DDX20 DDX43 DICER1	1.35e-04	107	86	5	PF00271
Domain	HELICc	DHX37 DHX35 DDX20 DDX43 DICER1	1.35e-04	107	86	5	SM00490
Domain	Helicase_C	DHX37 DHX35 DDX20 DDX43 DICER1	1.41e-04	108	86	5	IPR001650
Domain	HELICASE_CTER	DHX37 DHX35 DDX20 DDX43 DICER1	1.48e-04	109	86	5	PS51194
Domain	HELICASE_ATP_BIND_1	DHX37 DHX35 DDX20 DDX43 DICER1	1.48e-04	109	86	5	PS51192
Domain	DEXDc	DHX37 DHX35 DDX20 DDX43 DICER1	1.48e-04	109	86	5	SM00487
Domain	Helicase_ATP-bd	DHX37 DHX35 DDX20 DDX43 DICER1	1.54e-04	110	86	5	IPR014001
Domain	IQ	MYO1A MYO1D MYO1E OBSCN	3.22e-04	71	86	4	PF00612
Domain	L-lactate/malate_DH	LDHAL6A UEVLD	5.76e-04	8	86	2	IPR001557
Domain	Ldh_1_N	LDHAL6A UEVLD	5.76e-04	8	86	2	PF00056
Domain	Lactate/malate_DH_N	LDHAL6A UEVLD	5.76e-04	8	86	2	IPR001236
Domain	-	LDHAL6A UEVLD	7.39e-04	9	86	2	3.90.110.10
Domain	Lactate/malate_DH_C	LDHAL6A UEVLD	7.39e-04	9	86	2	IPR022383
Domain	Lactate_DH/Glyco_Ohase_4_C	LDHAL6A UEVLD	7.39e-04	9	86	2	IPR015955
Domain	BEACH_dom	WDR81 NBEA	7.39e-04	9	86	2	IPR000409
Domain	Ldh_1_C	LDHAL6A UEVLD	7.39e-04	9	86	2	PF02866
Domain	BEACH	WDR81 NBEA	7.39e-04	9	86	2	PS50197
Domain	Beach	WDR81 NBEA	7.39e-04	9	86	2	PF02138
Domain	-	WDR81 NBEA	7.39e-04	9	86	2	1.10.1540.10
Domain	Beach	WDR81 NBEA	7.39e-04	9	86	2	SM01026
Domain	IQ_motif_EF-hand-BS	MYO1A MYO1D MYO1E OBSCN	7.92e-04	90	86	4	IPR000048
Domain	IQ	MYO1A MYO1D MYO1E OBSCN	8.96e-04	93	86	4	PS50096
Domain	Cadherin_C	PCDHB15 PCDHB13 PCDHB7	9.50e-04	42	86	3	IPR032455
Domain	Cadherin_C_2	PCDHB15 PCDHB13 PCDHB7	9.50e-04	42	86	3	PF16492
Domain	-	LGALS16 LGALS13 NBEA EGFLAM	9.70e-04	95	86	4	2.60.120.200
Domain	Septin	SEPTIN8 SEPTIN10	1.58e-03	13	86	2	PF00735
Domain	G_SEPTIN_dom	SEPTIN8 SEPTIN10	1.58e-03	13	86	2	IPR030379
Domain	G_SEPTIN	SEPTIN8 SEPTIN10	1.58e-03	13	86	2	PS51719
Domain	Cadherin_CS	PCDHB15 PCDHB13 PCDHB7 DSG4	1.61e-03	109	86	4	IPR020894
Domain	Septin	SEPTIN8 SEPTIN10	1.84e-03	14	86	2	IPR016491
Domain	CADHERIN_1	PCDHB15 PCDHB13 PCDHB7 DSG4	1.84e-03	113	86	4	PS00232
Domain	Cadherin	PCDHB15 PCDHB13 PCDHB7 DSG4	1.84e-03	113	86	4	PF00028
Domain	CADHERIN_2	PCDHB15 PCDHB13 PCDHB7 DSG4	1.90e-03	114	86	4	PS50268
Domain	-	PCDHB15 PCDHB13 PCDHB7 DSG4	1.90e-03	114	86	4	2.60.40.60
Domain	CA	PCDHB15 PCDHB13 PCDHB7 DSG4	1.96e-03	115	86	4	SM00112
Domain	Cadherin-like	PCDHB15 PCDHB13 PCDHB7 DSG4	2.03e-03	116	86	4	IPR015919
Domain	Gal-bind_lectin	LGALS16 LGALS13	2.12e-03	15	86	2	PF00337
Domain	Gal-bind_lectin	LGALS16 LGALS13	2.12e-03	15	86	2	SM00908
Domain	GALECTIN	LGALS16 LGALS13	2.12e-03	15	86	2	PS51304
Domain	Galectin_CRD	LGALS16 LGALS13	2.12e-03	15	86	2	IPR001079
Domain	GLECT	LGALS16 LGALS13	2.12e-03	15	86	2	SM00276
Domain	Cadherin	PCDHB15 PCDHB13 PCDHB7 DSG4	2.16e-03	118	86	4	IPR002126
Domain	DUF1605	DHX37 DHX35	2.72e-03	17	86	2	IPR011709
Domain	OB_NTP_bind	DHX37 DHX35	2.72e-03	17	86	2	PF07717
Domain	HA2	DHX37 DHX35	3.06e-03	18	86	2	SM00847
Domain	HA2	DHX37 DHX35	3.06e-03	18	86	2	PF04408
Domain	Helicase-assoc_dom	DHX37 DHX35	3.06e-03	18	86	2	IPR007502
Domain	Cadherin_2	PCDHB15 PCDHB13 PCDHB7	3.35e-03	65	86	3	PF08266
Domain	Cadherin_N	PCDHB15 PCDHB13 PCDHB7	3.35e-03	65	86	3	IPR013164
Domain	DSRM	ADARB1 DICER1	3.41e-03	19	86	2	SM00358
Domain	Ras	RHOH RAB43 NKIRAS2 RAB33B	3.60e-03	136	86	4	PF00071
Domain	dsrm	ADARB1 DICER1	3.77e-03	20	86	2	PF00035
Domain	UPAR_LY6	CD177 PLAUR	3.77e-03	20	86	2	PF00021
Domain	DS_RBD	ADARB1 DICER1	4.16e-03	21	86	2	PS50137
Domain	LY6_UPAR	CD177 PLAUR	4.56e-03	22	86	2	PS00983
Domain	LY6_UPA_recep-like	CD177 PLAUR	4.56e-03	22	86	2	IPR016054
Pubmed	Differential localization and dynamics of class I myosins in the enterocyte microvillus.	MYO1A MYO1D MYO1E	6.04e-08	4	87	3	20089841
Pubmed	Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia.	MYO1G MYO1D MYO1E	3.01e-07	6	87	3	12486594
Pubmed	Single-neuron diversity generated by Protocadherin-β cluster in mouse central and peripheral nervous systems.	PCDHB15 PCDHB13 PCDHB7	1.79e-06	10	87	3	22969705
Pubmed	Genomic alterations link Rho family of GTPases to the highly invasive phenotype of pancreas cancer.	PAK4 RIOK3	6.19e-06	2	87	2	19050074
Pubmed	Pharmacogenetics of KCNQ channel activation in 2 potassium channelopathy mouse models of epilepsy.	KCNA1 KCNQ1	6.19e-06	2	87	2	29265344
Pubmed	Human brush border myosin-I and myosin-Ic expression in human intestine and Caco-2BBe cells.	MYO1A MYO1E	6.19e-06	2	87	2	9858156
Pubmed	The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.	PCDHB15 PCDHB13 PCDHB7	1.67e-05	20	87	3	11322959
Pubmed	A novel epigenetic marker, Ten-eleven translocation family member 2 (TET2), is identified in the intractable epileptic brain and regulates ATP binding cassette subfamily B member 1 (ABCB1) in the blood-brain barrier.	TET1 ABCB1	1.85e-05	3	87	2	35235761
Pubmed	The genetic landscape of familial congenital hydrocephalus.	WDR81 MPDZ	1.85e-05	3	87	2	28556411
Pubmed	Mammalian septins nomenclature.	SEPTIN8 SEPTIN10	1.85e-05	3	87	2	12475938
Pubmed	Neurobeachin and the Kinesin KIF21B Are Critical for Endocytic Recycling of NMDA Receptors and Regulate Social Behavior.	KIF21B NBEA	1.85e-05	3	87	2	29847800
Pubmed	Predicting chemosensitivity to gemcitabine and cisplatin based on gene polymorphisms and mRNA expression in non-small-cell lung cancer cells.	RRM1 ABCB1	3.70e-05	4	87	2	25560468
Pubmed	[Differential expressions of MDR-1, RRM-1, EGFR and ERCC-1 in primary tumors and metastatic lymph nodes of NSCLC patients].	RRM1 ABCB1	3.70e-05	4	87	2	23948418
Pubmed	Single nucleotide polymorphisms in MDR1 gen correlates with outcome in advanced non-small-cell lung cancer patients treated with cisplatin plus vinorelbine.	RRM1 ABCB1	3.70e-05	4	87	2	20627363
Pubmed	Single nucleotide polymorphisms and outcome in docetaxel-cisplatin-treated advanced non-small-cell lung cancer.	RRM1 ABCB1	3.70e-05	4	87	2	15277258
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SEPTIN8 RHOH CAND2 MYPN TET1 PAK4 OBSCN BOD1L1 NOL9 KIF13A DNA2	8.25e-05	1084	87	11	11544199
Pubmed	Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.	KCNQ1 SLC26A9	9.22e-05	6	87	2	24018950
Pubmed	Genetic determinants of methotrexate toxicity in rheumatoid arthritis patients: a study of polymorphisms affecting methotrexate transport and folate metabolism.	MTRR ABCB1	9.22e-05	6	87	2	18607581
Pubmed	Myosins: a diverse superfamily.	MYO1A MYO1D	1.29e-04	7	87	2	10722873
Pubmed	The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing.	KCNQ1 DICER1	1.29e-04	7	87	2	19144718
Pubmed	Comparative interactome analysis of α-arrestin families in human and Drosophila.	CAND2 MYO1D MYO1E BOD1L1 DDX20 ABCB1	1.39e-04	313	87	6	38270169
Pubmed	Mapping the Genetic Landscape of Human Cells.	DHX37 WDR70 BOD1L1 NOL9 RRM1 DNA2 DICER1	1.41e-04	451	87	7	30033366
Pubmed	Black carbon exposures, blood pressure, and interactions with single nucleotide polymorphisms in MicroRNA processing genes.	DDX20 DICER1	1.72e-04	8	87	2	20211803
Pubmed	A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death.	LGALS16 LGALS13	1.72e-04	8	87	2	19497882
Pubmed	KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium.	KCNA1 KCNQ1	1.72e-04	8	87	2	21859894
Pubmed	A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins.	MYO1A MYO1D MYO1E	1.99e-04	45	87	3	22114352
Pubmed	Mapping of unconventional myosins in mouse and human.	MYO1A MYO1D MYO1E	2.41e-04	48	87	3	8884266
Pubmed	The DNA sequence and biological annotation of human chromosome 1.	KIF21B CADM3 FMO4 OBSCN DDX20 NOL9 ALDH9A1 CSMD2 XCL1 ATP13A2	2.55e-04	1031	87	10	16710414
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	SEPTIN8 MYPN PAK4 WDR70 WDR81 RIOK3 DHX35 NOL9 SEPTIN10 DENND4C	2.69e-04	1038	87	10	26673895
Pubmed	Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.	SLC8A1 KCNQ1	2.75e-04	10	87	2	25055868
Pubmed	Domperidone treatment for gastroparesis: demographic and pharmacogenetic characterization of clinical efficacy and side-effects.	KCNQ1 ABCB1	2.75e-04	10	87	2	21063774
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIF21B SEPTIN8 CAND2 TET1 PAK4 DNA2 DICER1	3.71e-04	529	87	7	14621295
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHB15 PCDHB13 PCDHB7	4.01e-04	57	87	3	32633719
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHB15 PCDHB13 PCDHB7	4.22e-04	58	87	3	30377227
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	SEPTIN8 MYO1D MYO1E DHX37 PAK4 MTRR DHX35 DICER1	4.67e-04	724	87	8	36232890
Pubmed	Pharmacogenomic variations in treatment protocols for childhood acute lymphoblastic leukemia.	MTRR ABCB1	4.74e-04	13	87	2	19774638
Pubmed	Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.	GART MTRR	4.74e-04	13	87	2	19936946
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	MYO1E DHX37 WDR70 NOL9 RRM1 RAB33B	5.14e-04	400	87	6	35013556
Pubmed	Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types.	MYO1A MYO1E	5.52e-04	14	87	2	8022818
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHB15 PCDHB13 PCDHB7	6.74e-04	68	87	3	11230163
Pubmed	A unique role of cohesin-SA1 in gene regulation and development.	PCDHB15 PCDHB13	7.26e-04	16	87	2	22415368
Pubmed	Localization of septin proteins in the mouse cochlea.	SEPTIN8 SEPTIN10	7.26e-04	16	87	2	22575789
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHB15 PCDHB13 PCDHB7	7.96e-04	72	87	3	10380929
Pubmed	Postsynaptic and differential localization to neuronal subtypes of protocadherin beta16 in the mammalian central nervous system.	PCDHB15 PCDHB13	8.21e-04	17	87	2	18279309
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHB15 PCDHB13 PCDHB7	8.62e-04	74	87	3	10817752
Pubmed	Ubiquitin-like protein 3 (UBL3) is required for MARCH ubiquitination of major histocompatibility complex class II and CD86.	RAB43 CCT4	9.22e-04	18	87	2	35411049
Pubmed	Wilms Tumor Predisposition	KCNQ1 DICER1	9.22e-04	18	87	2	20301471
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHB15 PCDHB13 PCDHB7	9.68e-04	77	87	3	10835267
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	CCT4 DDX20 ALDH9A1 DICER1	9.96e-04	175	87	4	25756610
Pubmed	Distinct and Cooperative Functions for the Protocadherin-α, -β and -γ Clusters in Neuronal Survival and Axon Targeting.	PCDHB15 PCDHB13	1.03e-03	19	87	2	28066179
Pubmed	Androglobin, a chimeric mammalian globin, is required for male fertility.	SEPTIN8 SEPTIN10	1.03e-03	19	87	2	35700329
Pubmed	Animal Models of Congenital Cardiomyopathies Associated With Mutations in Z-Line Proteins.	MYPN OBSCN	1.03e-03	19	87	2	27171814
Pubmed	Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.	GART MTRR SLC2A12	1.04e-03	79	87	3	18978678
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHB15 PCDHB13 PCDHB7	1.08e-03	80	87	3	10716726
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	MYO1D DHX37 GART CCT4 ADARB1 DICER1	1.17e-03	469	87	6	37314180
Pubmed	Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo.	ERGIC3 GART WDR70 SDF2 ABCB1	1.38e-03	326	87	5	17015433
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	DOCK3 KCNQ1 NBEA CSMD2 KIF13A	1.44e-03	329	87	5	17474147
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	CADM3 CSMD2 DICER1	1.52e-03	90	87	3	15033168
Pubmed	Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma.	DDX20 DICER1	1.65e-03	24	87	2	20732906
Pubmed	The DNA sequence and comparative analysis of human chromosome 10.	ZMYND11 MYPN TET1 DNA2 BORCS7	1.77e-03	345	87	5	15164054
Pubmed	Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.	SLC8A1 OBSCN	1.79e-03	25	87	2	38877142
Pubmed	Genetic variations in microRNA-related genes are novel susceptibility loci for esophageal cancer risk.	DDX20 DICER1	1.79e-03	25	87	2	19138993
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	MYPN MPDZ DICER1 DENND4C	1.91e-03	209	87	4	36779422
Pubmed	Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells.	SEPTIN8 RRM1	1.93e-03	26	87	2	15890332
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	PAK4 GART MPDZ CCT4 BOD1L1 RRM1 DENND4C	2.01e-03	708	87	7	39231216
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX37 GART WDR70 RIOK3 CCT4 DDX20 DDX43 NOL9 ALDH9A1 RRM1	2.03e-03	1353	87	10	29467282
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ERGIC3 PAK4 WDR81 KIF13A DENND4C BORCS7 UEVLD	2.19e-03	719	87	7	35337019
Pubmed	The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation.	KIF21B CADM3	2.24e-03	28	87	2	24448406
Pubmed	Novel genes differentially expressed in cortical regions during late neurogenesis.	ATP13A2 SVOPL	2.24e-03	28	87	2	17614941
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	SEPTIN8 CAND2 GART MPDZ CCT4 DDX20 NOL9 ALDH9A1 SDF2	2.32e-03	1149	87	9	35446349
Pubmed	An integrated workflow for charting the human interaction proteome: insights into the PP2A system.	WDR81 CCT4 ADARB1	2.36e-03	105	87	3	19156129
Pubmed	The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair.	WDR70 ALDH9A1 RRM1	2.42e-03	106	87	3	31024071
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	WDR70 MPDZ BOD1L1 DDX20 ALDH9A1 DICER1 DENND4C	2.44e-03	733	87	7	34672954
Cytoband	5q31	SEPTIN8 PCDHB15 PCDHB13 PCDHB7	7.08e-05	115	87	4	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	SEPTIN8 PCDHB15 PCDHB13 FSTL4 PCDHB7	2.67e-04	298	87	5	chr5q31
Cytoband	10q24.32	ELOVL3 BORCS7	9.54e-04	24	87	2	10q24.32
Cytoband	Ensembl 112 genes in cytogenetic band chr10q21	MYPN TET1 DNA2	1.50e-03	118	87	3	chr10q21
Cytoband	Ensembl 112 genes in cytogenetic band chr1q24	FMO4 ALDH9A1 XCL1	1.93e-03	129	87	3	chr1q24
Cytoband	19q13.2	LGALS16 CD177 PAK4	3.81e-03	164	87	3	19q13.2
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51D1 LDHAL6A KCNQ1 RRM1 UEVLD	4.45e-03	564	87	5	chr11p15
GeneFamily	Myosins, class I	MYO1G MYO1A MYO1D MYO1E	9.89e-09	8	64	4	1097
GeneFamily	WD repeat domain containing\|BEACH domain containing	WDR81 NBEA	4.37e-04	9	64	2	1230
GeneFamily	Septins	SEPTIN8 SEPTIN10	9.38e-04	13	64	2	732
GeneFamily	Galectins	LGALS16 LGALS13	1.26e-03	15	64	2	629
GeneFamily	DEAH-box helicases	DHX37 DHX35	1.43e-03	16	64	2	500
GeneFamily	Clustered protocadherins	PCDHB15 PCDHB13 PCDHB7	1.51e-03	64	64	3	20
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-ILC2\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1G KIF21B RHOH RAB43 FSTL4 XCL1 SVOPL	6.27e-08	179	87	7	b8bc03f60a7ac76ea6ee90d0512f0dc1d1d2a087
Disease	X-13548 measurement	ZMYND11 DIP2C	7.44e-06	2	81	2	EFO_0021353
Disease	Hydrocephalus	WDR81 MPDZ	2.23e-05	3	81	2	cv:C0020255
Disease	Congenital hydrocephalus	WDR81 MPDZ	2.23e-05	3	81	2	cv:C0020256
Disease	hydrocephalus (is_implicated_in)	WDR81 MPDZ	1.11e-04	6	81	2	DOID:10908 (is_implicated_in)
Disease	hereditary spastic paraplegia (implicated_via_orthology)	NIPA2 ATP13A2 BORCS7	2.27e-04	43	81	3	DOID:2476 (implicated_via_orthology)
Disease	temporal lobe epilepsy (implicated_via_orthology)	KCNA1 ABCB1	2.65e-04	9	81	2	DOID:3328 (implicated_via_orthology)
Disease	Parkinson Disease, Secondary Vascular	ATP13A2 ABCB1	4.83e-04	12	81	2	C0751414
Disease	Atherosclerotic Parkinsonism	ATP13A2 ABCB1	4.83e-04	12	81	2	C0751415
Disease	Secondary Parkinson Disease	ATP13A2 ABCB1	4.83e-04	12	81	2	C0030569
Disease	niacinamide measurement	SEPTIN8 FMO4	4.83e-04	12	81	2	EFO_0010511
Disease	Hypertrophic Cardiomyopathy	MYPN OBSCN KCNQ1	5.24e-04	57	81	3	C0007194
Disease	ulcerative colitis (is_implicated_in)	MTRR ABCB1	9.85e-04	17	81	2	DOID:8577 (is_implicated_in)
Disease	Adrenocortical carcinoma	RRM1 ABCB1	1.11e-03	18	81	2	C0206686
Disease	response to selective serotonin reuptake inhibitor	SLC26A9 EGFLAM CSMD2	1.51e-03	82	81	3	EFO_0005658
Disease	nose morphology measurement, mouth morphology measurement	KCNQ1 DNA2	1.51e-03	21	81	2	EFO_0007843, EFO_0007955
Disease	creatinine measurement	PLIN4 KIF21B SLC8A1 CAND2 MYPN OBSCN DIP2C KCNQ1 OPLAH	1.62e-03	995	81	9	EFO_0004518
Disease	status epilepticus (biomarker_via_orthology)	SLC8A1 PLAUR ABCB1	2.66e-03	100	81	3	DOID:1824 (biomarker_via_orthology)
Disease	Psychotic Disorders	TET1 ADARB1 ABCB1	2.74e-03	101	81	3	C0033975

Protein segments in the cluster

Peptide	Gene	Start	Entry
TGRVIATFTCSGEKE	ALDH9A1	36	P49189
FNCGTGVAIIVSETK	EGFLAM	451	Q63HQ2
GCSITEAVTILGNKL	C8orf74	81	Q6P047
FLGTQGSETITCVLK	CSMD2	721	Q7Z408
GSETITCVLKEGSVV	CSMD2	726	Q7Z408
SIGDSKVFVCGGVTT	CCIN	521	Q13939
RATAIKVTDISGGCG	BOLA3	46	Q53S33
LDVGLTSTLVGTKGC	CD177	251	Q8N6Q3
DLIVQAKSGTGKTCV	DDX20	101	Q9UHI6
SDETVVAGGTVVLKC	CADM3	36	Q8N126
IVCLNTGSGKTFIAV	DICER1	61	Q9UPY3
IIVIGDSNVGKTCLT	RAB33B	36	Q9H082
LVLVGDASVGKTCVV	RAB43	21	Q86YS6
CGGGERKTTVSCTKI	ADAMTS19	931	Q8TE59
ASLASTGVGVVKVIS	SLC2A12	316	Q8TD20
LALVGSSGCGKSTVV	ABCB1	1066	P08183
VILVCGSQDVGKSTF	NOL9	301	Q5SY16
GTFSGKCTVLIQVID	PCDHB13	326	Q9Y5F0
VVLCVGSKGQVFATS	KCNQ1	211	P51787
VTIGGKIVGSLCAIA	KCNA1	381	Q09470
PVSLSVGSCVIIKGT	LGALS16	11	A8MUM7
VGSCVIIKGTLIDSS	LGALS16	16	A8MUM7
CILITGESGSGKTEA	MYO1A	96	Q9UBC5
STGIGRKGCQLTTED	EPHX4	246	Q8IUS5
LSTATTEVLRKGVCT	MTRR	476	Q9UBK8
IDDGSGKTATGTICI	DSG4	471	Q86SJ6
ASVLTGCTVAKIGLS	OR51D1	146	Q8NGF3
RVKTCGGATVTIVSG	ERGIC3	21	Q9Y282
KCIRTLTSSGQVISG	KIF21B	1381	O75037
AVIGAGVSGLSSIKC	FMO4	6	P31512
VGVCSSGIFTKVTRK	ABCC11	876	Q96J66
VGALFGKVLSQTTIC	POU5F2	151	Q8N7G0
SVIGAFSVSCVKGLG	NIPA2	186	Q8N8Q9
KVVVCGQASVGKTSI	NKIRAS2	6	Q9NYR9
VLVSSDLVCKISGFG	EPHA10	776	Q5JZY3
GLSGKCSVSVKVLDV	PCDHB15	326	Q9Y5E8
CIGTTLGAASSKEVV	MROH1	651	Q8NDA8
AKVISVSTGTKCING	ADARB1	366	P78563
AGVVGLSTAVCISKL	DDO	11	Q99489
VSVGKDATLSCQIVG	OBSCN	21	Q5VST9
CVTGGQKTAASLRVT	OBSCN	4141	Q5VST9
PVSLSVGSCVIIKGT	LGALS13	11	Q9UHV8
GLSGKCTVVVDVTDI	PCDHB7	326	Q9Y5E2
KETEGTVTCTGAEGR	BOD1L1	1721	Q8NFC6
VLAVVTRTGFCTAKG	ATP13A2	391	Q9NQ11
CSGILGSIFSIVKTS	DOCK3	876	Q8IZD9
TVLLTGGLKQTVCFI	ELOVL3	91	Q9HB03
QTVVIVGETGCGKST	DHX35	71	Q9H5Z1
NTLRCEVSGIKGGTT	FSTL4	821	Q6MZW2
TCKDGSVLGVTVTRT	DIP2C	501	Q9Y2E4
AVTDICVIVTSKGET	DENND4C	156	Q5VZ89
LTEKVTTCGTDVIAL	BORCS7	21	Q96B45
ATGSGLATNVCRKIT	CAND2	121	O75155
GTGKTTTICTLVRIL	DNA2	651	P51530
VIVCGETGSGKTTQV	DHX37	271	Q8IY37
CGSIVLKSAFSVGIT	C1QTNF7	141	Q9BXJ2
DLIGVAQTGTGKTLC	DDX43	281	Q9NXZ2
DIVCSKSVLISVGDT	OTOGL	996	Q3ZCN5
KIGEGSTGIVCIATV	PAK4	326	O96013
STGIVCIATVRSSGK	PAK4	331	O96013
ILSVSIGCVTARSTK	KIF13A	1051	Q9H1H9
IVLTGTKDTVCSGVT	PLIN4	446	Q96Q06
KTVLTGTKDTVCSGV	PLIN4	511	Q96Q06
VLTGTKDTVCSGVTG	PLIN4	711	Q96Q06
TVCSGVTGAVNVAKG	PLIN4	916	Q96Q06
GGKSQVASLCVSLVV	SLC26A9	401	Q7LBE3
VTKTGDICISVGAEV	OPLAH	711	O14841
KCVLVGDSAVGKTSL	RHOH	6	Q15669
VSVCAELGLVISGAK	NBEA	2786	Q8NFP9
ITGCASPGKTVTIVV	CCT4	376	P50991
QVKVVALCAGSGSSV	NIF3L1	291	Q9GZT8
LGVVTCGSVVKLLNT	SDF2	21	Q99470
VCGSKSDSAVVVTGG	SVOPL	311	Q8N434
VNVVCSGGITVVSTK	TET1	1356	Q8NFU7
ETITGCISTGKESVV	RIOK3	251	O14730
GVGSEVSDKRTCVSL	XCL1	21	P47992
TGLKITSLTEVVCGL	PLAUR	81	Q03405
CETTIEISKGRTGLG	MPDZ	1626	O75970
ISKSAGGIGVAVSCI	RRM1	241	P23921
KLIVTGTSIQRGCGS	WDR70	436	Q9NW82
TAVKLSTGCSGILIS	PRSS35	146	Q8N3Z0
NILCVGETGIGKSTL	SEPTIN8	46	Q92599
CVGETGIGKSTLIDT	SEPTIN10	71	Q9P0V9
SVTEAVVAGIAKACG	GART	546	P22102
VVTDSCGRVESSGKI	ZSCAN26	191	Q16670
VETLTVGCKGSKAGI	ZMYND11	66	Q15326
CILGTNGVSEVIKTT	UEVLD	431	Q8IX04
EVVTGTVSNKIGVCS	WDR81	1881	Q562E7
NKISIVGTGSVGVAC	LDHAL6A	21	Q6ZMR3
GCTIGLKDSVTAVVF	SLC8A1	826	P32418
TCIVISGESGAGKTE	MYO1D	96	O94832
QCVIISGESGAGKTV	MYO1E	106	Q12965
TCIVISGESGAGKTE	MYO1G	96	B0I1T2
VTEGSPVTFTCKIVG	MYPN	956	Q86TC9