Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentequatorial microtubule organizing center

TUBGCP4 TUBGCP5

1.40e-045792GO:0000923
GeneOntologyCellularComponentcentrosome

HK2 CLIC5 ALMS1 TTC28 KIZ PKHD1 TACC2 TUBGCP4 TUBGCP5 AXIN2

6.29e-047707910GO:0005813
GeneOntologyCellularComponentmicrotubule organizing center

HK2 CLIC5 ALMS1 TTC28 STARD9 KIZ PKHD1 TACC2 TUBGCP4 TUBGCP5 AXIN2

6.55e-049197911GO:0005815
GeneOntologyCellularComponentgamma-tubulin ring complex

TUBGCP4 TUBGCP5

7.59e-0411792GO:0000931
HumanPhenoEsophageal varix

PHKA2 ALMS1 ARHGAP31 PKHD1 F5

6.45e-0647305HP:0002040
DomainGCP

TUBGCP4 TUBGCP5

1.71e-045782IPR007259
DomainSpc97_Spc98

TUBGCP4 TUBGCP5

1.71e-045782PF04130
DomainRap_GAP

GARNL3 RALGAPA2

7.58e-0410782PF02145
DomainRap_GAP_dom

GARNL3 RALGAPA2

9.24e-0411782IPR000331
DomainRAPGAP

GARNL3 RALGAPA2

9.24e-0411782PS50085
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ALMS1 TTC28 ZCCHC8 SEC16A AGFG1 RTN3 ARHGAP17 TACC2 HUWE1 CLSPN EMSY

1.22e-07588811138580884
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

A2M PHKA2 HK2 MAP1B TTC28 EIF2B5 GRB7 GON4L TUBGCP4 CLSPN PTK7

3.31e-07650811138777146
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

NHSL1 MET PTPN2 HK2 MAP1B PRICKLE2 RTN3 TACC2 GRIN2B POLD3 HUWE1 CNOT2 STT3B PTK7

3.56e-071139811436417873
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

ALMS1 TTC28 SEC16A AGFG1 ARHGAP17 POLD3 HUWE1 TIPRL CLSPN CNOT2 STT3B

1.07e-06733811134672954
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

TGFB1I1 MXRA5 TRPM3 NEXMIF PRICKLE2 PKHD1 PCARE HUWE1 PHF8 MTPAP IQCE

1.12e-06736811129676528
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

FAM171A1 NHSL1 KIAA0930 ALMS1 MAP1B TTC28 ZCCHC8 STARD9 SEC16A AGFG1 ARHGAP17

5.03e-06861811136931259
Pubmed

Non-proteolytic ubiquitination of Hexokinase 2 by HectH9 controls tumor metabolism and cancer stem cell expansion.

HK2 HUWE1

5.36e-06281231201299
Pubmed

MET Oncogene Controls Invasive Growth by Coupling with NMDA Receptor.

MET GRIN2B

5.36e-06281236139568
Pubmed

Protease Activity Profiling via Programmable Phage Display of Comprehensive Proteome-Scale Peptide Libraries.

CASP1 HUWE1

5.36e-06281233099407
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

GATAD2A ALMS1 TTC28 ZCCHC8 SEC16A GAS7 WDFY3 PHF8 CLSPN RALGAPA2 TUBGCP5 MTPAP

1.03e-051116811231753913
Pubmed

Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein.

AGFG1 COPS6

1.60e-0538128195203
Pubmed

A nuclear protein tyrosine phosphatase activates p53 and induces caspase-1-dependent apoptosis.

PTPN2 CASP1

1.60e-05381212459463
Pubmed

Regulation of the Met receptor-tyrosine kinase by the protein-tyrosine phosphatase 1B and T-cell phosphatase.

MET PTPN2

1.60e-05381218819921
Pubmed

Endothelial PAS domain-containing protein 1 confers TKI-resistance by mediating EGFR and MET pathways in non-small cell lung cancer cells.

MET EPAS1

1.60e-05381225831463
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PCF11 HIVEP3 KIAA0930 ALMS1 TRPM3 GAS7 RALGAPA2 TUBGCP5

2.00e-0549381815368895
Pubmed

Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.

HIVEP3 NKX2-4 KIZ

2.08e-052381324925725
Pubmed

Wnt7b stimulates embryonic lung growth by coordinately increasing the replication of epithelium and mesenchyme.

TGFB1I1 EPAS1 AXIN2

3.82e-052881318367557
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

ALMS1 MAP1B TTC28 SEC16A HUWE1 PHF8 TIPRL EMSY

4.29e-0554981838280479
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

MAP1B EIF2B5 RTN3 HUWE1 TUBGCP4 STT3B AAR2

4.79e-0540881733766124
Pubmed

Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?

GARNL3 TTC28 MUC16 TAC3 HUWE1

4.99e-0517081523314748
Pubmed

GCP5 and GCP6: two new members of the human gamma-tubulin complex.

TUBGCP4 TUBGCP5

5.33e-05581211694571
Pubmed

Structural basis for substrate recognition and chemical inhibition of oncogenic MAGE ubiquitin ligases.

PCF11 HUWE1

5.33e-05581233004795
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PCF11 PHKA2 KIZ TACC2 TUBGCP4 COPS6 TUBGCP5 MTPAP CNOT2 FBXL3 AAR2

7.47e-051155811120360068
Pubmed

Direct regulation of GAS6/AXL signaling by HIF promotes renal metastasis through SRC and MET.

MET EPAS1

7.99e-05681225187556
Pubmed

Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.

MET EPAS1

7.99e-05681223928995
Pubmed

Mapping the Genetic Landscape of Human Cells.

EIF2B5 POLD3 TUBGCP4 CLSPN TUBGCP5 MTPAP EMSY

8.96e-0545181730033366
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

HIVEP3 TRPM3 GON4L HUWE1

9.39e-0510181410997877
Pubmed

A synthetic interaction screen identifies factors selectively required for proliferation and TERT transcription in p53-deficient human cancer cells.

TTC28 GRIN2B POLD3 STT3B

1.09e-0410581423284306
Pubmed

Identification of a new tissue-kallikrein-binding protein.

A2M KNG1

1.12e-0478123643793
Pubmed

A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3' End Processing Complex.

PCF11 HUWE1

1.12e-04781231980388
Pubmed

Mechanism of KMT5B haploinsufficiency in neurodevelopment in humans and mice.

GRIN2B WDFY3

1.12e-04781236897941
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

A2M ALMS1 MAP1B TTC28 SEC16A GON4L HUWE1 F5

1.31e-0464581825281560
Pubmed

Defects in Synaptic Plasticity, Reduced NMDA-Receptor Transport, and Instability of Postsynaptic Density Proteins in Mice Lacking Microtubule-Associated Protein 1A.

MAP1B GRIN2B

1.49e-04881226609151
Pubmed

SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.

MAP1B EIF2B5 SEC16A RTN3 HUWE1 TUBGCP4 STT3B AAR2

1.49e-0465781836180527
Pubmed

Identification of proteins that interact with alpha A-crystallin using a human proteome microarray.

PTPN2 KIZ TUBGCP5 KNG1

1.71e-0411881424453475
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PTPN2 HK2 ALMS1 TTC28 ZCCHC8 SEC16A RTN3 TACC2 HUWE1 GTPBP10 MTPAP STT3B

1.74e-041496811232877691
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

NHSL1 PHKA2 POLD3 PHF8 COPS6

1.79e-0422381533187986
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

ALMS1 TTC28 SEC16A WDFY3 PHF8

1.86e-0422581512168954
Pubmed

Direct binding of NuMA to tubulin is mediated by a novel sequence motif in the tail domain that bundles and stabilizes microtubules.

TUBGCP4 TUBGCP5

1.91e-04981211956313
Pubmed

Dynamic changes of NuMA during the cell cycle and possible appearance of a truncated form of NuMA during apoptosis.

TUBGCP4 TUBGCP5

1.91e-0498128838651
Pubmed

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice.

MAP1B WDFY3

1.91e-04981218083104
Pubmed

CDK5RAP2 stimulates microtubule nucleation by the gamma-tubulin ring complex.

TUBGCP4 TUBGCP5

2.38e-041081221135143
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

KIAA0930 EIF2B5 SEC16A PCARE TIPRL TUBGCP4 COPS6 MTPAP CNOT2 STT3B AAR2

2.41e-041321811127173435
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TBC1D16 HIVEP3 NHSL1 KIAA0930 SEC16A ARHGAP17 WDFY3 HUWE1 RALGAPA2 IQCE

2.45e-041105811035748872
Pubmed

Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

GATAD2A MAP1B RTN3 COPS6

2.56e-0413181431006538
Pubmed

A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes.

MET PTK7

2.91e-04118128247543
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

HK2 GATAD2A MAP1B EIF2B5 SEC16A WDFY3 POLD3 HUWE1 PHF8 MTPAP AAR2

2.96e-041353811129467282
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

HIVEP3 WDFY3

3.48e-041281227824329
Pubmed

Genome-wide association study and meta-analysis of intraocular pressure.

PKHD1 GAS7

3.48e-041281224002674
Pubmed

The intracellular NADH level regulates atrophic nonunion pathogenesis through the CtBP2-p300-Runx2 transcriptional complex.

HK2 GATAD2A TTC28 KIZ

3.66e-0414481430585266
Pubmed

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.

ALMS1 SEC16A AGFG1

3.78e-046081334761192
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

MET PTPN2 MAP1B ZCCHC8 SEC16A TIPRL PTK7

3.86e-0457381728330616
Pubmed

A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.

GATAD2A ZCCHC8 SEC16A EMSY

3.86e-0414681423892456
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

PCF11 MET TTC28 SEC16A MUC16 HUWE1 CLSPN IQCE

4.58e-0477781835844135
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

FAM171A1 NHSL1 MET SEC16A RALGAPA2 PTK7

4.58e-0442181636976175
Pubmed

Ethanol potentiates HIV-1 gp120-induced apoptosis in human neurons via both the death receptor and NMDA receptor pathways.

CASP1 GRIN2B

4.79e-041481215749123
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

ALMS1 TUBGCP4 TUBGCP5

5.01e-046681312221128
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

RANBP17 GATAD2A EIF2B5 RTN3 EPAS1

5.33e-0428381518854154
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

HK2 TTC28 POLD3 HUWE1 TUBGCP5 MTPAP AAR2

5.38e-0460681736538041
Pubmed

The orphan GPCR, Gpr161, regulates the retinoic acid and canonical Wnt pathways during neurulation.

AXIN2 PTK7

5.52e-041581225753732
Pubmed

The Meckel-Gruber syndrome protein TMEM67 controls basal body positioning and epithelial branching morphogenesis in mice via the non-canonical Wnt pathway.

ALMS1 AXIN2

5.52e-041581226035863
Pubmed

Proteomic identification of common SCF ubiquitin ligase FBXO6-interacting glycoproteins in three kinds of cells.

A2M MET HK2 HUWE1 COPS6 FBXL3 STT3B

5.75e-0461381722268729
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

GATAD2A MAP1B SEC16A TACC2 POLD3 EMSY

6.06e-0444481634795231
Pubmed

Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia.

A2M RUNX1T1 FBXL3 KNG1 AXIN2

6.14e-0429281512819125
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

KIAA0930 ALMS1 TTC28 ZCCHC8 SEC16A TIPRL

6.20e-0444681624255178
Pubmed

Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

A2M KNG1 PTK7

6.21e-047181312754519
Pubmed

Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.

TTC28 STARD9 SEC16A HUWE1 TIPRL STT3B

6.42e-0444981631732153
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

TGFB1I1 ZCCHC8 EIF2B5 SEC16A AGFG1 RTN3 POLD3 CLSPN CNOT2

6.92e-04103881926673895
Pubmed

Genetic analysis in a Dutch study sample identifies more ulcerative colitis susceptibility loci and shows their additive role in disease risk.

PTPN2 GAS7

7.12e-041781219861958
Pubmed

JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse.

MAP1B GRIN2B

7.12e-041781226627310
Pubmed

VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland.

PRICKLE2 AXIN2

8.00e-041881231068622
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

PHKA2 HK2 GATAD2A MAP1B HUWE1 RUNX1T1 MTPAP EMSY

8.67e-0485781825609649
Pubmed

The role of Lrp6-mediated Wnt/β-catenin signaling in the development and intervention of spinal neural tube defects in mice.

AXIN2 PTK7

8.93e-041981235514236
Pubmed

The ULK1-FBXW5-SEC23B nexus controls autophagy.

SEC16A FBXL3

9.91e-042081230596474
Pubmed

Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.

GZMK AXIN2

9.91e-042081219268448
Pubmed

Insights into the genetic architecture of early stage age-related macular degeneration: a genome-wide association study meta-analysis.

PCF11 CLIC5

9.91e-042081223326517
Pubmed

Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.

HK2 EPAS1

9.91e-042081233665549
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

A2M GATAD2A GON4L HUWE1 TUBGCP4

1.07e-0333181519490893
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

HK2 CLIC5 ALMS1 GON4L GAS7 COPS6

1.09e-0349781623414517
Pubmed

β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation.

AXIN2 PTK7

1.09e-032181224284205
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

HK2 ARHGAP17 POLD3 CNOT2 STT3B PTK7 AAR2

1.11e-0368681728380382
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

GATAD2A ZCCHC8 CLSPN EMSY AAR2

1.19e-0333981530415952
Pubmed

The protein interaction landscape of the human CMGC kinase group.

A2M CLIC5 ALMS1 ZCCHC8 HUWE1 CNOT2 AXIN2

1.20e-0369581723602568
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

RTN3 HUWE1

1.20e-032281237225996
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

ZCCHC8 EIF2B5 PHF8 CNOT2 EMSY

1.23e-0334181532971831
Pubmed

Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein.

A2M PLXDC1 KNG1

1.32e-039281337343697
Pubmed

Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1.

HUWE1 COPS6

1.43e-032481229871923
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

NHSL1 ALMS1 TTC28 SEC16A

1.47e-0320981436779422
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ALMS1 MAP1B ZCCHC8 SEC16A AGFG1 TACC2 TIPRL EMSY

1.50e-0393481833916271
Pubmed

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.

EPAS1 AXIN2

1.68e-032681226856890
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

MAP1B GON4L HUWE1 COPS6 FBXL3 STT3B

1.76e-0354781637267103
Pubmed

Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks.

MAP1B ZCCHC8 EMSY

1.77e-0310281326584622
Pubmed

Centrosome-related genes, genetic variation, and risk of breast cancer.

TACC2 TUBGCP4 AXIN2

1.77e-0310281320508983
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

PTPN2 KIAA0930 GRB7

1.77e-0310281315778465
Pubmed

Using an in situ proximity ligation assay to systematically profile endogenous protein-protein interactions in a pathway network.

A2M MET GRIN2B RUNX1T1 EPAS1

1.77e-0337181525241761
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

GATAD2A EMSY

1.81e-032781223395962
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ALMS1 SEC16A HUWE1

1.87e-031048139205841
Pubmed

Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TTC28 PHF8 IQCE

1.87e-0310481310470851
Pubmed

Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome.

HK2 AXIN2

1.95e-032881232369449
Pubmed

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.

PTPN2 EMSY

1.95e-032881218587394
InteractionFBXO42 interactions

ALMS1 TTC28 ZCCHC8 SEC16A AGFG1 ARHGAP17 TACC2 COPS6

7.93e-06259798int:FBXO42
Cytoband20p11.22

NKX2-4 RALGAPA2

8.55e-05881220p11.22
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

RANBP17 PHKA2 ALMS1 KIZ POLD3 HUWE1 PHF8 TUBGCP4 OSGIN2 RUNX1T1 CLSPN RALGAPA2 AXIN2

8.36e-068207813gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCellcontrol-HLA-DR-_S100A+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

KIAA0930 HK2 AGFG1 RTN3 GAS7 WDFY3 F5

8.13e-082008179e3e13a68bc1110fa000ec2d80f4c654ddbce17e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAM171A1 ARHGAP31 RUNX1T1 RALGAPA2 EPAS1

5.95e-071668168e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 GARNL3 MAP1B TTC28 STARD9 PRICKLE2

8.65e-07177816e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM171A1 CLIC5 ARHGAP31 PRICKLE2 EPAS1 STT3B

1.39e-061928164bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TTC28 ARHGAP31 STARD9 RUNX1T1 EPAS1

1.39e-0619281628eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellCOVID-19-kidney-CD-PC|kidney / Disease (COVID-19 only), tissue and cell type

FAM171A1 MXRA5 TRPM3 NEXMIF KIZ PKHD1

1.43e-06193816738689d009e4b118d7ce3171a207294b95cbe78b
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M FAM171A1 TTC28 PRICKLE2 RUNX1T1 EPAS1

1.48e-0619481671ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellIPF-Stromal-Pericyte|World / Disease state, Lineage and Cell class

TGFB1I1 A2M MAP1B PLXDC1 RUNX1T1 FXYD1

1.48e-061948161a41da29d5adaf766a84eff0003b959e4523f7f1
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAM171A1 ARHGAP31 RUNX1T1 RALGAPA2 EPAS1

1.52e-06195816d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

HIVEP3 MET NEXMIF PKHD1 KNG1 PTK7

1.57e-0619681604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellIPF-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

TGFB1I1 A2M MXRA5 MAP1B RUNX1T1 FXYD1

1.57e-061968167fc9894ceb79dab9f0495acc84e2d6d0d1c69bb7
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

NHSL1 MXRA5 MAP1B PLXDC1 GAS7 F5

1.57e-0619681624d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAM171A1 ARHGAP31 RUNX1T1 RALGAPA2 EPAS1

1.57e-061968168f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAM171A1 ARHGAP31 RUNX1T1 RALGAPA2 EPAS1

1.57e-0619681648b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 A2M MAP1B PLXDC1 FXYD1 EPAS1

1.57e-061968165146976881d79642ebe5dcbcf89e0252713a9ef2
ToppCellnucseq-Endothelial-Endothelial_Vascular|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTC28 ARHGAP31 PRICKLE2 RUNX1T1 RALGAPA2 EPAS1

1.57e-06196816686533fd3fba8e4df96b9dd1307e870e89db4332
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M FAM171A1 ARHGAP31 RUNX1T1 RALGAPA2 EPAS1

1.57e-06196816473980c827443464d08a0be28c53e3536369b12a
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 A2M MAP1B PLXDC1 FXYD1 EPAS1

1.57e-06196816ebac1d6af7a5732707d82d01285c086b19d8ae62
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1I1 A2M MAP1B PLXDC1 RUNX1T1 EPAS1

1.71e-06199816bd9b36dcf61eaa628ce1b70d21c5783b64c29e8f
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

MET HK2 GATAD2A SEC16A IQCE

1.07e-05159815655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B STARD9 GAS7 GRIN2B

1.47e-051708156035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B STARD9 GAS7 GRIN2B

1.47e-05170815c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B STARD9 GAS7 GRIN2B

1.47e-05170815dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TBC1D16 MXRA5 PRICKLE2 RUNX1T1

1.65e-05174815f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TGFB1I1 TBC1D16 CLIC5 GZMK PTK7

1.65e-05174815e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCellControl-Neuronal_cells-Neuronal_cells|Control / group, cell type (main and fine annotations)

FAM171A1 NHSL1 MAP1B GRIN2B RALGAPA2

1.74e-0517681598c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

TGFB1I1 TBC1D16 CLIC5 GZMK PTK7

1.74e-05176815bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCellControl-Neuronal_cells|Control / group, cell type (main and fine annotations)

FAM171A1 NHSL1 MAP1B GRIN2B RALGAPA2

1.74e-05176815c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCellCOVID-19-Heart-EC_2|COVID-19 / Disease (COVID-19 only), tissue and cell type

A2M MET ARHGAP31 RUNX1T1 EPAS1

1.89e-051798152a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CLIC5 MAP1B PCARE FXYD1 F5

1.94e-05180815d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAM171A1 ARHGAP31 GRIN2B RUNX1T1 EPAS1

2.10e-05183815c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.16e-05184815688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M MAP1B PLXDC1 RUNX1T1 EPAS1

2.21e-051858157092436b4db90289516ed130ade596e3021cffaf
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ARHGAP31 GZMK RUNX1T1 EPAS1

2.21e-05185815fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M MAP1B PLXDC1 RUNX1T1 EPAS1

2.21e-05185815a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M MAP1B PLXDC1 FXYD1 AXIN2

2.21e-05185815e1fbec55b71f604189eb2431768fadbaa0453a83
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M MAP1B PLXDC1 FXYD1 AXIN2

2.21e-051858159d933cd5ebc8368fd37aa83113d2dfa6938ff72d
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ARHGAP31 GZMK RUNX1T1 EPAS1

2.33e-0518781537d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP31 STARD9 RUNX1T1 CLSPN EPAS1

2.33e-0518781535c382c0aabd46906113e5db30ea24bb8e658899
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B PLXDC1 STARD9 RUNX1T1 EPAS1

2.33e-0518781548bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellCOVID-19-Endothelial_cells-Pulmonary_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

FAM171A1 MET RUNX1T1 RALGAPA2 EPAS1

2.33e-051878152d20193a6cacdfa4877457c97b0077408942186c
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M ARHGAP31 GZMK RUNX1T1 EPAS1

2.33e-05187815ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MET PKHD1 GRB7 KNG1

2.33e-0518781577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

TTC28 ARHGAP31 PRICKLE2 RALGAPA2 EPAS1

2.33e-05187815fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B PLXDC1 STARD9 RUNX1T1 EPAS1

2.33e-05187815958402fcc78f4c7a7d13d659d776f3817137975f
ToppCellControl-Endothelial_cells-Arterial_endothelial_cells|Control / group, cell type (main and fine annotations)

FAM171A1 TTC28 RUNX1T1 RALGAPA2 EPAS1

2.33e-0518781581affaab3fe3e1daea45ada6445e906ddd33950e
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

A2M TTC28 PRICKLE2 RUNX1T1 EPAS1

2.39e-05188815117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TGFB1I1 MAP1B PLXDC1 STARD9 EPAS1

2.39e-05188815ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

FAM171A1 TRPM3 NEXMIF KIZ PKHD1

2.39e-051888158f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TTC28 ARHGAP31 RUNX1T1 EPAS1

2.45e-051898156463890d8dbee4bc198f91628a5f784970de786a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B PLXDC1 STARD9 RUNX1T1 EPAS1

2.45e-05189815fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B GAS7 GRIN2B RALGAPA2

2.52e-05190815876bd2eb9ed2624cb23bdcf6b989e4fa34d099e3
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAM171A1 CLIC5 ARHGAP31 PRICKLE2 EPAS1

2.52e-05190815474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_cortex-lymphatic_endothelial_cell_of_renal_cortex|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B GAS7 GRIN2B RALGAPA2

2.52e-05190815be9f36127028f52ca5fc1b32ba15a6c26aad69ac
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 MAP1B GAS7 GRIN2B RALGAPA2

2.52e-0519081509a8855901c3c9332dbaab3e40166485b696d0f1
ToppCell3'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TGFB1I1 A2M TTC28 FXYD1 PTK7

2.52e-05190815591310e615700321a010a4b90405cbbbbdb3aade
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

MET NEXMIF MUC16 ITPRID1 FER1L6

2.52e-0519081551ca9ef4df3220487152fcf684147730637c7cc1
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAM171A1 TTC28 RUNX1T1 RALGAPA2 EPAS1

2.58e-0519181550601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M PRICKLE2 RUNX1T1 DNAI3 PTK7

2.58e-05191815c54c420a94dc749ebc67fc64c5614663f4b9798d
ToppCellControl-Endothelial-VE_Capillary_B|World / Disease state, Lineage and Cell class

TTC28 PRICKLE2 RUNX1T1 RALGAPA2 EPAS1

2.58e-05191815c672c8e28d06d555335976b3f8bd2ea6d3b34aae
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|343B / Donor, Lineage, Cell class and subclass (all cells)

A2M FAM171A1 TTC28 RUNX1T1 EPAS1

2.58e-0519181527a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCellControl-Endothelial-VE_Capillary_B|Control / Disease state, Lineage and Cell class

TTC28 PRICKLE2 RUNX1T1 RALGAPA2 EPAS1

2.58e-05191815322237793a1278bafb14e63cab688b353e352dcc
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M PRICKLE2 RUNX1T1 DNAI3 PTK7

2.58e-05191815cb0aee740b08f7d5fdd2717ecf7429043b277ae7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RANBP17 NHSL1 MET CLIC5 PKHD1

2.58e-05191815ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellCOVID-19-kidney-TAL|COVID-19 / Disease (COVID-19 only), tissue and cell type

MET NEXMIF PKHD1 GRB7 KNG1

2.58e-05191815fe55475ce0666ab5122447a813dc2369e24947b8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B PLXDC1 ARHGAP17 RUNX1T1 EPAS1

2.58e-051918157b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|343B / Donor, Lineage, Cell class and subclass (all cells)

A2M FAM171A1 TTC28 RUNX1T1 EPAS1

2.58e-051918151dfcff08e01e6a695953334342bcfde04ba005ad
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1B PLXDC1 ARHGAP17 RUNX1T1 EPAS1

2.58e-05191815cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 RUNX1T1 RALGAPA2 EPAS1

2.65e-051928153259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TTC28 ARHGAP31 RUNX1T1 EPAS1

2.65e-0519281556b021c297a21dff357531f21e2464f85186106d
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTC28 ARHGAP31 PRICKLE2 RALGAPA2 EPAS1

2.71e-05193815f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCell3'-Distal_airway-Mesenchymal-Mesenchymal_Myocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 A2M MAP1B PLXDC1 FXYD1

2.71e-0519381587ce81ff5b27d9c4300826d76ff5a62e9c408d5d
ToppCellILEUM-inflamed-(8)_Smooth_muscle_cells|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

TGFB1I1 A2M MXRA5 TAC3 RUNX1T1

2.71e-05193815084c88f08ce0ecd6c9f4334caed370eb2154f896
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

A2M MAP1B TTC28 PRICKLE2 RUNX1T1

2.71e-05193815e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TTC28 ARHGAP31 PRICKLE2 RALGAPA2 EPAS1

2.71e-05193815ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

TGFB1I1 A2M MAP1B PLXDC1 EPAS1

2.78e-05194815d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

A2M MXRA5 TRPM3 FXYD1 EPAS1

2.78e-05194815638b9fdce64ed00243b5303800ec66207d5fd640
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Mesenchymal-choroid_plexus/mesenchymal-like_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

A2M MXRA5 TRPM3 FXYD1 EPAS1

2.78e-05194815e9868c22934b6c0ac35e3e8270ec0b671bc6582a
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GAS7 RUNX1T1 FXYD1 AXIN2 PTK7

2.78e-051948154f9bd0ded0dde1df885850714f29e73e992539a5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.78e-05194815f76808666fb875fc787751cbfd924d9be20a8192
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.78e-05194815f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.78e-05194815a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell3'-Distal_airway-Mesenchymal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 A2M MAP1B PLXDC1 FXYD1

2.78e-05194815f5e3e675187afb6efa774f2a8d685efcf813de82
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M TTC28 ARHGAP31 RUNX1T1 EPAS1

2.85e-051958156bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 A2M MAP1B FXYD1 EPAS1

2.85e-05195815e10b21e4dba4483efc4c82d6e395524246ca14a8
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAM171A1 TTC28 RUNX1T1 RALGAPA2 EPAS1

2.85e-05195815023e3c97dd3696d74f002ff8da0c04d876c82aef
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 A2M MAP1B PLXDC1 EPAS1

2.85e-051958159ab3c5b0fb12d406408122a535b717bfe184bbcf
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFB1I1 A2M MAP1B PLXDC1 EPAS1

2.85e-0519581521263d138c81f6a0219f2cd93126cfafd35732b2
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TGFB1I1 A2M MAP1B PLXDC1 FXYD1

2.92e-05196815c373465e34e2dd581247962d59e0477aae877079
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.92e-051968158ad8efb631164b46f0c082572270188e5ead20bf
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 A2M PLXDC1 STARD9 FXYD1

2.92e-051968159d18381d7aaa063094a5df769a04c73350471525
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

HIVEP3 GAS7 RUNX1T1 FXYD1 PTK7

2.92e-0519681554f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCellCOVID-19-lung-Capillary_Aerocytes|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP31 STARD9 PRICKLE2 RALGAPA2 EPAS1

2.92e-0519681549cc0a2b9739abad61dff7292ea0b14d28ff35c4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.92e-05196815ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 ARHGAP31 STARD9 RUNX1T1 EPAS1

2.92e-05196815b8f89a50114932c08fc5daac4b549adfe9df8e66
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP31 STARD9 RUNX1T1 EPAS1

2.92e-051968159606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TTC28 ARHGAP31 STARD9 RUNX1T1 EPAS1

2.92e-05196815145fcf73deba9638b391a1af6c39fa205dc9829f
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TGFB1I1 A2M MAP1B PLXDC1 FXYD1

2.92e-051968158b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCell3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFB1I1 A2M PLXDC1 STARD9 FXYD1

2.92e-05196815a52cb512c6173be92aa9c4d96e2abbc32f45478d
ToppCellCOVID-19-lung-Capillary_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TTC28 ARHGAP31 PRICKLE2 RALGAPA2 EPAS1

2.92e-05196815ac28e9be288af6f00a841aea4ce4b99aed6b4505
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

A2M MAP1B PLXDC1 EPAS1

9.51e-0550524GAVISH_3CA_METAPROGRAM_FIBROBLASTS_PERICYTE_LIKE
DrugMephenytoin [50-12-4]; Down 200; 18.4uM; MCF7; HT_HG-U133A

TGFB1I1 HIVEP3 MAP1B TTC28 GON4L GAS7 WDFY3

5.69e-061958073580_DN
DrugFluspirilen [1841-19-6]; Down 200; 8.4uM; MCF7; HT_HG-U133A

MET PTPN2 ALMS1 CASP1 GON4L WDFY3 EMSY

5.69e-061958075008_DN
DiseaseNeurodevelopmental Disorders

HIVEP3 NEXMIF GRIN2B WDFY3 PTK7

5.23e-0693795C1535926
Diseasesyndromic X-linked intellectual disability (implicated_via_orthology)

HUWE1 PHF8

1.96e-048792DOID:0060309 (implicated_via_orthology)
DiseaseIntellectual Disability

MAP1B TRPM3 ZCCHC8 GON4L GRIN2B FBXL3 STT3B

1.98e-04447797C3714756
Diseasenucleus accumbens volume change measurement

MUC16 ITPRID1

3.83e-0411792EFO_0021493
Diseasediastolic blood pressure, systolic blood pressure

TBC1D16 MET GATAD2A ALMS1 MAP1B TRPM3 SEC16A PTK7

4.28e-04670798EFO_0006335, EFO_0006336
Diseaseopioid dependence

NHSL1 MAP1B ARHGAP17 TACC2 GRIN2B

4.45e-04237795EFO_0005611
DiseaseColorectal Carcinoma

HIVEP3 MAP1B PKHD1 POLD3 RUNX1T1 ITPRID1 F5 AXIN2

5.82e-04702798C0009402
Diseaseinositol measurement

TRPM3 ARHGAP17

6.31e-0414792EFO_0010504
Diseasepeanut allergy measurement

KIZ EMSY

8.29e-0416792EFO_0007017
DiseaseBenign neoplasm of stomach

MET AXIN2

9.38e-0417792C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

MET AXIN2

9.38e-0417792C0496905
DiseaseCarcinoma in situ of stomach

MET AXIN2

9.38e-0417792C0154060
DiseaseIschemic stroke, venous thromboembolism, stroke, Abnormal thrombosis, deep vein thrombosis, pulmonary embolism

F5 KNG1

9.38e-0417792EFO_0000712, EFO_0003827, EFO_0003907, EFO_0004286, HP_0001977, HP_0002140
Diseaseevent free survival time, urinary bladder cancer

ARHGAP17 GRIN2B

1.18e-0319792EFO_0000482, MONDO_0001187
DiseaseStomach Carcinoma

MET AXIN2

1.44e-0321792C0699791
Diseasehair color

KIAA0930 CLIC5 PKHD1 DNAI3 AXIN2

1.50e-03311795EFO_0003924
Diseasebreast cancer, COVID-19

TTC28 GON4L

1.58e-0322792MONDO_0007254, MONDO_0100096
Diseasephysical activity

PCF11 PKHD1 AAR2

1.72e-0388793EFO_0003940
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

MET EPAS1

1.73e-0323792C1708353
Diseasesensory peripheral neuropathy, remission

GAS7 RUNX1T1

1.73e-0323792EFO_0009785, MONDO_0002321
Diseasepartial thromboplastin time

F5 KNG1

1.88e-0324792EFO_0004310
Diseasereaction time measurement

FAM171A1 GATAD2A TTC28 PKHD1 TACC2 GRIN2B EPAS1

1.92e-03658797EFO_0008393
DiseaseAdenocarcinoma of large intestine

MET AXIN2 PTK7

2.21e-0396793C1319315
Diseaseamino acid measurement

ALMS1 TACC2 GRIN2B RUNX1T1 TUBGCP5 EPAS1 AXIN2

2.27e-03678797EFO_0005134
Diseaseacute kidney failure (implicated_via_orthology)

CASP1 EPAS1

2.38e-0327792DOID:3021 (implicated_via_orthology)
Diseasecerebral white matter volume change measurement, age at assessment

PRICKLE2 GAS7

2.56e-0328792EFO_0008007, EFO_0021499

Protein segments in the cluster

PeptideGeneStartEntry
KTEPEHRPMSSIFFD

EPAS1

596

Q99814
SGSMSVHPRPEDKTR

CEACAM18

366

A8MTB9
PMTKHTDLPVSVFES

COPS6

156

Q7L5N1
KEVSPHSRPFMASIQ

GZMK

31

P49863
FPEGATPAEITKHSM

AAR2

216

Q9Y312
PKEVDFHSSSQMPSP

ALMS1

2691

Q8TCU4
KSHSKAPETMPSEQF

AXIN2

556

Q9Y2T1
FMASESIHTPPAVTK

CCDC180

366

Q9P1Z9
QSFTDLHSPTEKMIT

DNAI3

326

Q8IWG1
MKEDLPSPSSFTIQH

CLIC5

131

Q9NZA1
VFSPSKSFVHLEPMS

A2M

451

P01023
MVASVPFVKSTEPHL

RANBP17

386

Q9H2T7
SVMESSKSHAAEPVR

IQCE

351

Q6IPM2
DLSPAFDHSPNKIMT

PTPN2

296

P17706
RTSHSDMKSERRPPS

GATAD2A

86

Q86YP4
MVPRTTPKFSHSKSD

MUC16

11501

Q8WXI7
MSRSVDHLERPTSFP

FAM171A1

541

Q5VUB5
MSLSPKHTTPFSVSD

NKX2-4

1

Q9H2Z4
TISPPSSMEEDKFSR

MAP1B

1206

P46821
MPHAEYEVTRPTATS

ITPRID1

546

Q6ZRS4
RTEKHSTMPDSPVDV

RUNX1T1

31

Q06455
MHERVTSFSTPPTPE

KIAA0930

281

Q6ICG6
HPTAAVKMLPTFVRS

HK2

56

P52789
MTMIFKESSPSHPTR

EIF2B5

181

Q13144
MSPEKSHRVISPSSG

NHSL1

841

Q5SYE7
RPTSDHSPTQDKMVS

OR2M2

261

Q96R28
TMAKAESPKEHDPFT

FXYD1

16

O00168
AFIDTAQHMLKTPPT

TUBGCP4

371

Q9UGJ1
PSSRQHTMVSFLKPV

TUBGCP5

541

Q96RT8
THTPSTAMETAIPFR

MTPAP

131

Q9NVV4
AILSMRDFSTEHKSP

KIZ

166

Q2M2Z5
SHPDVTEPMRFRSAT

RALGAPA2

701

Q2PPJ7
SMHISSSLPPDTQKF

HUWE1

3941

Q7Z6Z7
FKSSPHSLFPEKMVS

GRB7

191

Q14451
AKQSHMEEFTPPSRE

PCF11

526

O94913
RHPISSLKYTEDMTP

PRICKLE2

521

Q7Z3G6
TSFPEHRVLSFKSDM

OSGIN2

376

Q9Y236
DTMSSTEPPSKHAVT

GTPBP10

366

A4D1E9
TEPPSKHAVTTSKMD

GTPBP10

371

A4D1E9
RPEHKTSDSTFLVFM

CASP1

221

P29466
STARPSFMDLPKSHF

FBXL3

146

Q9UKT7
TPARSTHSEAPPSKM

GON4L

1021

Q3T8J9
IKEETTVSPPHTSMA

KNG1

396

P01042
MTQEKRHSPESPSIA

EMSY

811

Q7Z589
EESSPAFKPSMIRSH

GARNL3

311

Q5VVW2
PSSTTREMTPHEIKF

PHKA2

1106

P46019
TEVPSTAPMSGEKHR

POM121L1P

306

Q3SYA9
EPHLSKTSRPMDASS

PCARE

466

A6NGG8
PPMSPSQEHKETRDS

PCARE

1091

A6NGG8
MASTTHPEKPLVTEG

FER1L6

551

Q2WGJ9
HPKAEMRPSFSELVS

MET

1321

P08581
MTDFKTTPPVEVLHE

RTN3

681

O95197
RSHKSFPTDISQMSP

F5

1161

P12259
IFPEMHSDSASKDVP

ARHGAP17

851

Q68EM7
DKFRHSSLSEMSPPD

NEXMIF

1061

Q5QGS0
PPETAHMSVRKSTGD

GAS7

141

O60861
SHRASPPMTVETISK

PKHD1

3646

P08F94
VPLTDFSPVMDHSRE

STARD9

1081

Q9P2P6
TSSVHRPPAMTVKKE

POLD3

421

Q15054
PPHRVKSISMTTFTQ

AGFG1

61

P52594
FMTSPSPKHLKTDDS

CLSPN

1311

Q9HAW4
PHRSEKDMLASPSTS

CNOT2

51

Q9NZN8
STATKIHSPIPDMSK

ZCCHC8

651

Q6NZY4
SDVTSKSFPDDLPRM

ZBTB8A

266

Q96BR9
HKPSSLSYEPEMRSS

WDFY3

966

Q8IZQ1
AMEQVSSRPTSPEKF

SEC16A

1431

O15027
TFPRDHKSVTADTEM

PYROXD1

281

Q8WU10
SRESKISSLMHVPPS

TIPRL

216

O75663
MAEPSAPESKHKSSL

STT3B

1

Q8TCJ2
PIVKSHSFMFSPSRS

TRPM3

1541

Q9HCF6
TMNSTFSEIFRKEHP

TKTL2

346

Q9H0I9
LPSSETHPEESMYKR

TBC1D16

381

Q8TBP0
KVSKETYTMATAPHP

HIVEP3

1656

Q5T1R4
STMDFSTHQAVPDPK

TACC2

1206

O95359
IMDHLPPSSTVTDSK

ARHGAP31

1356

Q2M1Z3
EMSIKDSPSQHSGRP

TTC28

2256

Q96AY4
MTLPSPSFTVRDVEH

PHF8

171

Q9UPP1
LETTTSHMPRSGAPK

TGFB1I1

11

O43294
KEIPMSVPEISSSQH

PLXDC1

236

Q8IUK5
PKESTSPEKRDMHDF

TAC3

71

Q9UHF0
SDKMHFPRSSLQPIT

PTK7

786

Q13308
LHMSKPSIPSKFTDR

MXRA5

1676

Q9NR99
DMLSEHSFIPEPKSS

GRIN2B

306

Q13224