Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGT2P GGT1 GGT3P GGT5

3.68e-106464GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGT2P GGT1 GGT3P GGT5

3.68e-106464GO:0002951
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGT2P GGT1 GGT3P GGT5

1.71e-098464GO:0103068
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGT2P GGT1 GGT3P GGT5

3.08e-099464GO:0036374
GeneOntologyMolecularFunctionomega peptidase activity

GGT2P GGT1 GGT3P GGT5

4.40e-0816464GO:0008242
GeneOntologyMolecularFunctionthreonine-type peptidase activity

GGT2P GGT1 GGT3P GGT5

1.16e-0720464GO:0070003
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

VHL VHLL PRAMEF33 PRAMEF10

3.78e-0582464GO:1990756
GeneOntologyMolecularFunctionenzyme-substrate adaptor activity

VHL VHLL PRAMEF33 PRAMEF10

6.73e-0595464GO:0140767
GeneOntologyMolecularFunctiontranscription elongation factor activity

VHL VHLL

1.85e-049462GO:0003711
GeneOntologyMolecularFunctionaminoacyltransferase activity

CDK8 VHL TRIM14 GGT2P GGT1 GGT3P GGT5

1.99e-04532467GO:0016755
GeneOntologyMolecularFunctioncatalytic activity, acting on a tRNA

GGT2P GGT1 GGT3P GGT5

3.35e-04144464GO:0140101
GeneOntologyMolecularFunctionacyltransferase activity

CDK8 VHL AANAT TRIM14 GGT2P GGT1 GGT3P GGT5

3.50e-04775468GO:0016746
GeneOntologyMolecularFunctioncyclin-dependent protein kinase activity

CDK8 CDK19

2.17e-0330462GO:0097472
GeneOntologyMolecularFunctioncyclin-dependent protein serine/threonine kinase activity

CDK8 CDK19

2.17e-0330462GO:0004693
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

FRS3 ANKRD13B VHL VHLL PRAMEF33 PRAMEF10 TRIM14 ZNF653

4.59e-031160468GO:0030674
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF33 PRAMEF10

7.13e-0355462GO:0042974
GeneOntologyBiologicalProcessleukotriene D4 biosynthetic process

GGT2P GGT1 GGT3P GGT5

4.50e-0910464GO:1901750
GeneOntologyBiologicalProcessglutathione catabolic process

GGT2P GGT1 GGT3P GGT5

7.06e-0911464GO:0006751
GeneOntologyBiologicalProcessleukotriene D4 metabolic process

GGT2P GGT1 GGT3P GGT5

1.06e-0812464GO:1901748
GeneOntologyBiologicalProcessglutathione biosynthetic process

GGT2P GGT1 GGT3P GGT5

1.02e-0720464GO:0006750
GeneOntologyBiologicalProcessleukotriene biosynthetic process

GGT2P GGT1 GGT3P GGT5

1.54e-0722464GO:0019370
GeneOntologyBiologicalProcessnonribosomal peptide biosynthetic process

GGT2P GGT1 GGT3P GGT5

1.54e-0722464GO:0019184
GeneOntologyBiologicalProcesscysteine biosynthetic process

GGT2P GGT1 GGT3P

5.77e-078463GO:0019344
GeneOntologyBiologicalProcesspeptide biosynthetic process

GGT2P GGT1 GGT3P GGT5

9.56e-0734464GO:0043043
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

TYRP1 GGT2P GGT1 GGT3P GGT5

1.06e-0682465GO:1901568
GeneOntologyBiologicalProcesspeptide modification

GGT2P GGT1 GGT3P

1.23e-0610463GO:0031179
GeneOntologyBiologicalProcessmodified amino acid catabolic process

GGT2P GGT1 GGT3P GGT5

1.35e-0637464GO:0042219
GeneOntologyBiologicalProcessleukotriene metabolic process

GGT2P GGT1 GGT3P GGT5

2.06e-0641464GO:0006691
GeneOntologyBiologicalProcessfatty acid derivative biosynthetic process

GGT2P GGT1 GGT3P GGT5

5.42e-0652464GO:1901570
GeneOntologyBiologicalProcessmodified amino acid biosynthetic process

GGT2P GGT1 GGT3P GGT5

5.42e-0652464GO:0042398
GeneOntologyBiologicalProcesscysteine metabolic process

GGT2P GGT1 GGT3P

5.70e-0616463GO:0006534
GeneOntologyBiologicalProcesssulfur compound catabolic process

GGT2P GGT1 GGT3P GGT5

5.85e-0653464GO:0044273
GeneOntologyBiologicalProcessglutathione metabolic process

GGT2P GGT1 GGT3P GGT5

1.17e-0563464GO:0006749
GeneOntologyBiologicalProcesssulfur amino acid biosynthetic process

GGT2P GGT1 GGT3P

1.34e-0521463GO:0000097
GeneOntologyBiologicalProcessnegative regulation of hypoxia-inducible factor-1alpha signaling pathway

VHL VHLL

1.46e-053462GO:1902072
GeneOntologyBiologicalProcessicosanoid biosynthetic process

GGT2P GGT1 GGT3P GGT5

1.50e-0567464GO:0046456
GeneOntologyBiologicalProcessserine family amino acid biosynthetic process

GGT2P GGT1 GGT3P

2.31e-0525463GO:0009070
GeneOntologyBiologicalProcessregulation of hypoxia-inducible factor-1alpha signaling pathway

VHL VHLL

2.91e-054462GO:1902071
GeneOntologyBiologicalProcesshomeostasis of number of retina cells

VHL VHLL

2.91e-054462GO:0048877
GeneOntologyBiologicalProcessmelanin metabolic process

VHL VHLL TYRP1

3.64e-0529463GO:0006582
GeneOntologyBiologicalProcesspeptide metabolic process

GGT2P GGT1 GGT3P GGT5

3.67e-0584464GO:0006518
GeneOntologyBiologicalProcessamide biosynthetic process

AANAT GGT2P GGT1 GGT3P GGT5

3.95e-05172465GO:0043604
GeneOntologyBiologicalProcesssulfur compound biosynthetic process

EXT2 GGT2P GGT1 GGT3P GGT5

4.66e-05178465GO:0044272
GeneOntologyBiologicalProcessciliary body morphogenesis

VHL VHLL

7.26e-056462GO:0061073
GeneOntologyBiologicalProcesssulfur amino acid metabolic process

GGT2P GGT1 GGT3P

9.68e-0540463GO:0000096
GeneOntologyBiologicalProcessserine family amino acid metabolic process

GGT2P GGT1 GGT3P

1.20e-0443463GO:0009069
GeneOntologyBiologicalProcessmodified amino acid metabolic process

DUOX2 GGT2P GGT1 GGT3P GGT5

1.21e-04218465GO:0006575
GeneOntologyBiologicalProcesshypoxia-inducible factor-1alpha signaling pathway

VHL VHLL

1.73e-049462GO:0097411
GeneOntologyBiologicalProcesseye pigmentation

VHL VHLL

2.16e-0410462GO:0048069
GeneOntologyBiologicalProcessregulation protein catabolic process at postsynapse

VHL VHLL

2.16e-0410462GO:0140252
GeneOntologyBiologicalProcessiris morphogenesis

VHL VHLL

2.64e-0411462GO:0061072
GeneOntologyBiologicalProcessicosanoid metabolic process

GGT2P GGT1 GGT3P GGT5

2.81e-04142464GO:0006690
GeneOntologyBiologicalProcessphenol-containing compound metabolic process

VHL VHLL DUOX2 TYRP1

2.81e-04142464GO:0018958
GeneOntologyBiologicalProcessdevelopmental pigmentation

VHL VHLL TYRP1

2.94e-0458463GO:0048066
GeneOntologyBiologicalProcessnegative regulation of thymocyte apoptotic process

VHL VHLL

3.74e-0413462GO:0070244
GeneOntologyBiologicalProcesspancreatic A cell differentiation

VHL VHLL

4.35e-0414462GO:0003310
GeneOntologyBiologicalProcessregulation protein catabolic process at synapse

VHL VHLL

4.35e-0414462GO:0140250
GeneOntologyBiologicalProcesssecondary metabolic process

VHL VHLL TYRP1

4.50e-0467463GO:0019748
GeneOntologyBiologicalProcessproteinogenic amino acid biosynthetic process

GGT2P GGT1 GGT3P

4.91e-0469463GO:0170038
GeneOntologyBiologicalProcessnegative regulation of endothelial cell differentiation

VHL VHLL

5.02e-0415462GO:0045602
GeneOntologyBiologicalProcessL-amino acid biosynthetic process

GGT2P GGT1 GGT3P

5.12e-0470463GO:0170034
GeneOntologyBiologicalProcessalpha-amino acid biosynthetic process

GGT2P GGT1 GGT3P

6.77e-0477463GO:1901607
GeneOntologyBiologicalProcessnegative regulation of cellular response to hypoxia

VHL VHLL

7.28e-0418462GO:1900038
GeneOntologyBiologicalProcessproteinogenic amino acid metabolic process

TYRP1 GGT2P GGT1 GGT3P

7.62e-04185464GO:0170039
GeneOntologyBiologicalProcessamino acid metabolic process

TYRP1 GGT2P GGT1 GGT3P GGT5

8.37e-04332465GO:0006520
GeneOntologyBiologicalProcessregulation of thymocyte apoptotic process

VHL VHLL

9.01e-0420462GO:0070243
GeneOntologyBiologicalProcessamino acid biosynthetic process

GGT2P GGT1 GGT3P

9.33e-0486463GO:0008652
GeneOntologyBiologicalProcessL-amino acid metabolic process

TYRP1 GGT2P GGT1 GGT3P

1.18e-03208464GO:0170033
GeneOntologyBiologicalProcesspigment metabolic process

VHL VHLL TYRP1

1.21e-0394463GO:0042440
GeneOntologyBiologicalProcesssulfur compound metabolic process

EXT2 GGT2P GGT1 GGT3P GGT5

1.28e-03365465GO:0006790
GeneOntologyBiologicalProcessregulation of catecholamine metabolic process

VHL VHLL

1.53e-0326462GO:0042069
GeneOntologyBiologicalProcessthymocyte apoptotic process

VHL VHLL

1.65e-0327462GO:0070242
GeneOntologyBiologicalProcessregulation of cellular response to hypoxia

VHL VHLL

1.90e-0329462GO:1900037
GeneOntologyBiologicalProcessnegative regulation of T cell apoptotic process

VHL VHLL

2.31e-0332462GO:0070233
GeneOntologyBiologicalProcessalpha-amino acid metabolic process

TYRP1 GGT2P GGT1 GGT3P

2.34e-03251464GO:1901605
GeneOntologyBiologicalProcessbiogenic amine metabolic process

VHL VHLL AANAT

2.49e-03121463GO:0006576
GeneOntologyBiologicalProcesspigmentation

VHL VHLL TYRP1

2.73e-03125463GO:0043473
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

VHL VHLL PRAMEF33 PRAMEF10

3.41e-0647464GO:0031462
GeneOntologyCellularComponentCKM complex

CDK8 CDK19

4.72e-055462GO:1990508
GeneOntologyCellularComponentVCB complex

VHL VHLL

1.32e-048462GO:0030891
GeneOntologyCellularComponentcytoplasmic ubiquitin ligase complex

VHL VHLL

4.24e-0414462GO:0000153
GeneOntologyCellularComponentnuclear cyclin-dependent protein kinase holoenzyme complex

CDK8 CDK19

7.09e-0418462GO:0019908
GeneOntologyCellularComponentubiquitin ligase complex

CDK8 VHL VHLL PRAMEF33 PRAMEF10

1.02e-03352465GO:0000151
GeneOntologyCellularComponenttransferase complex

CDK8 VHL VHLL PRAMEF33 EXT2 CDC73 PRAMEF10 CDK19

1.08e-03963468GO:1990234
GeneOntologyCellularComponentcullin-RING ubiquitin ligase complex

VHL VHLL PRAMEF33 PRAMEF10

1.20e-03212464GO:0031461
MousePhenoabnormal circulating glutathione level

GGT2P GGT1 GGT3P

1.56e-075363MP:0030652
MousePhenoincreased circulating glutathione level

GGT2P GGT1 GGT3P

1.56e-075363MP:0030653
MousePhenoincreased glutathione level

GGT2P GGT1 GGT3P

1.56e-075363MP:0012606
MousePhenoglutathionuria

GGT2P GGT1 GGT3P

1.56e-075363MP:0013730
MousePhenodecreased circulating cysteine level

GGT2P GGT1 GGT3P

5.45e-077363MP:0030626
MousePhenoepididymis hypoplasia

GGT2P GGT1 GGT3P

8.71e-078363MP:0004932
MousePhenodecreased cysteine level

GGT2P GGT1 GGT3P

8.71e-078363MP:0030623
MousePhenonervous

GGT2P GGT1 GGT3P

1.30e-069363MP:0008912
MousePhenofailure of copulatory plug deposition

GGT2P GGT1 GGT3P

1.86e-0610363MP:0030983
MousePhenoseminal vesicle hypoplasia

GGT2P GGT1 GGT3P

1.86e-0610363MP:0005148
MousePhenoovary hypoplasia

GGT2P GGT1 GGT3P

1.86e-0610363MP:0005158
MousePhenoabnormal circulating cysteine level

GGT2P GGT1 GGT3P

2.55e-0611363MP:0030624
MousePhenoabsent tertiary ovarian follicles

GGT2P GGT1 GGT3P

2.55e-0611363MP:0011130
MousePhenoinfertility

LRRC56 DUOX2 TYRP1 PRAMEF33 PRAMEF10 MEI1 NUTM2F INSL6 GGT2P GGT1 NUTM2G GGT3P PKD1

4.08e-0611883613MP:0001924
MousePhenoabnormal cysteine level

GGT2P GGT1 GGT3P

4.41e-0613363MP:0030621
MousePhenodecreased glutathione level

GGT2P GGT1 GGT3P

4.41e-0613363MP:0012604
MousePhenoabnormal glutathione level

GGT2P GGT1 GGT3P

4.41e-0613363MP:0012603
MousePhenopriapism

GGT2P GGT1 GGT3P

5.60e-0614363MP:0003415
MousePhenodecreased thyroxine level

DUOX2 GGT2P GGT1 GGT3P

8.49e-0651364MP:0005471
MousePhenoabnormal spleen red pulp morphology

VHL VHLL GGT2P GGT1 GGT3P

8.55e-06110365MP:0002356
MousePhenoabnormal copulatory plug deposition

GGT2P GGT1 GGT3P

8.58e-0616363MP:0030982
MousePhenodecreased spleen red pulp amount

GGT2P GGT1 GGT3P

8.58e-0616363MP:0008477
MousePhenofailure of superovulation

GGT2P GGT1 GGT3P

1.25e-0518363MP:0031422
MousePhenoabnormal penile erection

GGT2P GGT1 GGT3P

1.25e-0518363MP:0001379
MousePhenooocyte degeneration

GGT2P GGT1 GGT3P

1.25e-0518363MP:0009093
MousePhenodisproportionate dwarf

GGT2P GGT1 GGT3P PKD1

1.33e-0557364MP:0002427
MousePhenoabnormal copulation physiology

GGT2P GGT1 GGT3P

1.48e-0519363MP:0031627
MousePhenoincreased circulating growth hormone level

GGT2P GGT1 GGT3P

1.48e-0519363MP:0005123
MousePhenomale infertility

LRRC56 TYRP1 PRAMEF33 PRAMEF10 MEI1 NUTM2F INSL6 GGT2P GGT1 NUTM2G GGT3P

1.57e-059443611MP:0001925
MousePhenodecreased circulating insulin-like growth factor I level

DUOX2 GGT2P GGT1 GGT3P

1.74e-0561364MP:0004701
MousePhenodiluted coat color

TYRP1 GGT2P GGT1 GGT3P

2.11e-0564364MP:0000371
MousePhenoabnormal sperm number

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

2.12e-05624369MP:0002673
MousePhenosmall vertebrae

GGT2P GGT1 GGT3P

2.34e-0522363MP:0004610
MousePhenoabnormal thyroxine level

DUOX2 GGT2P GGT1 GGT3P

2.38e-0566364MP:0005469
MousePhenodecreased male germ cell number

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

2.59e-05640369MP:0004901
MousePhenoincreased growth hormone level

GGT2P GGT1 GGT3P

2.68e-0523363MP:0005137
MousePhenouterus hypoplasia

GGT2P GGT1 GGT3P

2.68e-0523363MP:0001121
MousePhenoabnormal copulation behavior

GGT2P GGT1 GGT3P

3.06e-0524363MP:0009697
MousePhenoabnormal circulating insulin-like growth factor I level

DUOX2 GGT2P GGT1 GGT3P

3.36e-0572364MP:0004700
MousePhenoabnormal thyroid hormone level

DUOX2 GGT2P GGT1 GGT3P

3.75e-0574364MP:0005468
MousePhenonuclear cataract

GGT2P GGT1 GGT3P

3.92e-0526363MP:0010254
MousePhenoabnormal insulin-like growth factor I level

DUOX2 GGT2P GGT1 GGT3P

3.95e-0575364MP:0008831
MousePhenodecreased germ cell number

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

4.51e-05687369MP:0002209
MousePhenohindlimb paralysis

KIF1A GGT2P GGT1 GGT3P

4.85e-0579364MP:0000755
MousePhenoaminoaciduria

GGT2P GGT1 GGT3P

5.47e-0529363MP:0003311
MousePhenolimb paralysis

KIF1A GGT2P GGT1 GGT3P

5.89e-0583364MP:0013147
MousePhenoanovulation

GGT2P GGT1 GGT3P

8.12e-0533363MP:0008869
MousePhenodecreased circulating follicle stimulating hormone level

GGT2P GGT1 GGT3P

8.89e-0534363MP:0002790
MousePhenoincreased hepatic hemangioma incidence

VHL VHLL

9.61e-056362MP:0002047
MousePhenodecreased amino acid level

DUOX2 GGT2P GGT1 GGT3P

1.08e-0497364MP:0014528
MousePhenoabnormal skeleton development

DUOX2 EXT2 LOXL3 GGT2P GGT1 GGT3P PKD1

1.22e-04447367MP:0002113
MousePhenodecreased bone mass

GGT2P GGT1 GGT3P PKD1

1.22e-04100364MP:0004016
MousePhenodecreased circulating estradiol level

GGT2P GGT1 GGT3P

1.24e-0438363MP:0005181
MousePhenokidney cortex cyst

VHL VHLL PKD1

1.24e-0438363MP:0000522
MousePhenoabnormal gametes

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

1.27e-04785369MP:0001124
MousePhenoincreased activity of parathyroid

CDC73 PKD1

1.34e-047362MP:0003432
MousePhenodecreased tertiary ovarian follicle number

GGT2P GGT1 GGT3P

1.35e-0439363MP:0011129
MousePhenodecreased circulating estrogen level

GGT2P GGT1 GGT3P

1.56e-0441363MP:0003371
MousePhenoinduced hyperactivity

GGT2P GGT1 GGT3P

1.68e-0442363MP:0008911
MousePhenoincreased circulating pituitary hormone level

DUOX2 GGT2P GGT1 GGT3P

1.76e-04110364MP:0005117
MousePhenoabnormal parathyroid gland physiology

CDC73 PKD1

1.79e-048362MP:0003431
MousePhenodecreased follicle stimulating hormone level

GGT2P GGT1 GGT3P

1.93e-0444363MP:0005130
MousePhenodecreased long bone epiphyseal plate size

GGT2P GGT1 GGT3P

1.93e-0444363MP:0006396
MousePhenoabsent estrous cycle

GGT2P GGT1 GGT3P

1.93e-0444363MP:0009009
MousePhenoabnormal long bone hypertrophic chondrocyte zone

GGT2P GGT1 GGT3P PKD1

1.95e-04113364MP:0000165
MousePhenopreneoplasia

VHL VHLL

2.30e-049362MP:0002009
MousePhenoabnormal tertiary ovarian follicle number

GGT2P GGT1 GGT3P

2.35e-0447363MP:0011127
MousePhenoparalysis

KIF1A GGT2P GGT1 GGT3P

2.38e-04119364MP:0000753
MousePhenoabnormal male germ cell morphology

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

2.50e-04859369MP:0006362
MousePhenoabnormal amino acid derivative level

DUOX2 GGT2P GGT1 GGT3P

2.88e-04125364MP:0021145
MousePhenoshort femur

DUOX2 GGT2P GGT1 GGT3P

3.06e-04127364MP:0003109
MousePhenoincreased pituitary hormone level

DUOX2 GGT2P GGT1 GGT3P

3.15e-04128364MP:0003973
MousePhenoabnormal circulating estradiol level

GGT2P GGT1 GGT3P

3.18e-0452363MP:0005183
MousePhenodecreased femur size

DUOX2 GGT2P GGT1 GGT3P

3.34e-04130364MP:0030825
MousePhenopolycythemia

VHL VHLL

3.50e-0411362MP:0002872
MousePhenoabnormal male reproductive system physiology

LRRC56 TYRP1 PRAMEF33 PRAMEF10 MEI1 NUTM2F INSL6 GGT2P GGT1 NUTM2G GGT3P

3.52e-0413293611MP:0003698
MousePhenoaciduria

GGT2P GGT1 GGT3P

3.75e-0455363MP:0010028
MousePhenoabnormal spermatogenesis

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

3.84e-04910369MP:0001156
MousePhenooligozoospermia

VHL VHLL INSL6 GGT2P GGT1 GGT3P

4.00e-04384366MP:0002687
MousePhenoabnormal circulating estrogen level

GGT2P GGT1 GGT3P

4.17e-0457363MP:0003369
MousePhenoabnormal tertiary ovarian follicle morphology

GGT2P GGT1 GGT3P

4.17e-0457363MP:0009363
MousePhenoabnormal growth hormone level

GGT2P GGT1 GGT3P

4.17e-0457363MP:0003968
MousePhenoabnormal urine amino acid level

GGT2P GGT1 GGT3P

4.62e-0459363MP:0011468
MousePhenoimmotile sperm

GGT2P GGT1 GGT3P

4.62e-0459363MP:0020869
MousePhenodecreased circulating gonadotropin level

GGT2P GGT1 GGT3P

4.85e-0460363MP:0003363
MousePhenodecreased circulating testosterone level

GGT2P GGT1 GGT3P

4.85e-0460363MP:0002780
MousePhenoimpaired ovarian folliculogenesis

GGT2P GGT1 GGT3P

5.09e-0461363MP:0001129
MousePhenoabnormal germ cell morphology

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

5.11e-04946369MP:0002208
MousePhenoabnormal foam cell morphology

VHL VHLL PRAMEF33 PRAMEF10 MEI1 INSL6 GGT2P GGT1 GGT3P

5.43e-04954369MP:0009840
MousePhenopulmonary hypertension

VHL VHLL

5.75e-0414362MP:0003548
MousePhenoabnormal superovulation

GGT2P GGT1 GGT3P

6.42e-0466363MP:0009648
MousePhenoabsent corpus luteum

GGT2P GGT1 GGT3P

6.42e-0466363MP:0001134
MousePhenoincreased pulmonary artery pressure

VHL VHLL

6.63e-0415362MP:0004012
MousePhenoabnormal long bone epiphyseal plate proliferative zone

GGT2P GGT1 GGT3P

7.01e-0468363MP:0003662
MousePhenosmall epididymis

GGT2P GGT1 GGT3P

7.63e-0470363MP:0004930
MousePhenoabnormal pulmonary pressure

VHL VHLL

8.56e-0417362MP:0003547
MousePhenoabnormal circulating pituitary hormone level

DUOX2 GGT2P GGT1 GGT3P

9.59e-04172364MP:0005116
MousePhenoabnormal cartilage development

GGT2P GGT1 GGT3P PKD1

9.59e-04172364MP:0000164
MousePhenoabnormal long bone epiphyseal plate morphology

GGT2P GGT1 GGT3P PKD1

9.59e-04172364MP:0003055
MousePhenoincreased osteoclast cell number

GGT2P GGT1 GGT3P

1.01e-0377363MP:0004984
DomainGGT_peptidase

GGT1 GGT3P GGT5

4.24e-077443IPR000101
DomainG_glu_transpept

GGT1 GGT3P GGT5

4.24e-077443PF01019
DomainG_GLU_TRANSPEPTIDASE

GGT1 GGT3P GGT5

4.24e-077443PS00462
Domain-

VHL VHLL

5.42e-0624422.60.40.780
DomainVHL

VHL VHLL

5.42e-062442PF01847
DomainVHL_beta_dom

VHL VHLL

5.42e-062442IPR024053
DomainVHL

VHL VHLL

5.42e-062442IPR002714
DomainVHL_tumour_suppress_b/a_dom

VHL VHLL

5.42e-062442IPR022772
DomainNUT

NUTM2F NUTM2G

5.40e-055442IPR024310
DomainNUT_N

NUTM2F NUTM2G

5.40e-055442IPR024309
DomainNUT

NUTM2F NUTM2G

5.40e-055442PF12881
DomainNtn_hydrolases_N

GGT1 GGT5

2.73e-0333442IPR029055
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4B1 GGT2P GGT1 GGT3P GGT5

1.59e-0925305MM14858
PathwayREACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING

GGT2P GGT1 GGT3P GGT5

2.98e-0816304MM14680
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4B1 GGT2P GGT1 GGT3P GGT5

1.68e-0761305MM14861
PathwayREACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION

GGT2P GGT1 GGT3P GGT5

2.41e-0726304MM15190
PathwayWP_GLUTATHIONE_METABOLISM

GGT2P GGT1 GGT3P GGT5

2.83e-0727304MM15908
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

GGT2P GGT1 GGT3P GGT5

6.53e-0733304MM15963
PathwayWP_GLUTATHIONE_AND_ONECARBON_METABOLISM

GGT2P GGT1 GGT3P GGT5

8.33e-0735304MM15815
PathwayREACTOME_GLUTATHIONE_CONJUGATION

GGT2P GGT1 GGT3P GGT5

1.17e-0638304MM14600
PathwayREACTOME_PARACETAMOL_ADME

GGT2P GGT1 GGT3P GGT5

1.30e-0639304MM15695
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

CYP4B1 GGT1 GGT5

1.13e-0521303M27137
PathwayWP_EICOSANOID_SYNTHESIS

GGT2P GGT1 GGT3P

1.30e-0522303MM15961
PathwayWP_OXYLIPINS_PATHWAYS

GGT2P GGT1 GGT3P

1.71e-0524303MM17249
PathwayREACTOME_FATTY_ACID_METABOLISM

CYP4B1 GGT2P GGT1 GGT3P GGT5

2.68e-05170305MM15573
PathwayWP_OXIDATIVE_STRESS_AND_REDOX_PATHWAY

GGT2P GGT1 GGT3P GGT5

4.09e-0592304MM15823
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

GGT2P GGT1 GGT3P GGT5

7.39e-05107304MM14595
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

CYP4B1 GGT2P GGT1 GGT3P GGT5

8.97e-05219305MM14838
PathwayREACTOME_LTC4_CYSLTR_MEDIATED_IL4_PRODUCTION

GGT1 GGT5

9.13e-057302M29845
PathwayREACTOME_DRUG_ADME

GGT2P GGT1 GGT3P GGT5

1.12e-04119304MM15692
PathwayKEGG_TAURINE_AND_HYPOTAURINE_METABOLISM

GGT1 GGT5

1.95e-0410302M12882
PathwayWP_OMEGA6FATTY_ACIDS_IN_SENESCENCE

PTGDR GGT1 GGT5

2.35e-0457303M48332
PathwayREACTOME_RHOBTB3_ATPASE_CYCLE

VHL VHLL

2.38e-0411302MM15681
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

CYP4B1 GGT1 GGT5

2.61e-0459303M27140
PathwayREACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING

GGT1 GGT5

2.85e-0412302M27028
PathwayWP_LEUKOTRIENE_METABOLIC_PATHWAY

GGT1 GGT5

3.37e-0413302M45552
PathwayREACTOME_METABOLISM_OF_AMINE_DERIVED_HORMONES

DUOX2 AANAT

5.84e-0417302MM14829
PathwayREACTOME_METABOLISM_OF_AMINE_DERIVED_HORMONES

DUOX2 AANAT

6.56e-0418302M27118
PathwayREACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION

GGT1 GGT5

7.32e-0419302M27449
PathwayWP_GLUTATHIONE_METABOLISM

GGT1 GGT5

7.32e-0419302M39388
PathwayKEGG_SELENOAMINO_ACID_METABOLISM

GGT1 GGT5

1.38e-0326302M7151
PathwayREACTOME_PARACETAMOL_ADME

GGT1 GGT5

1.72e-0329302M45015
PathwayWP_PROSTAGLANDIN_AND_LEUKOTRIENE_METABOLISM_IN_SENESCENCE_WP5321

GGT1 GGT5

2.35e-0334302M48061
PathwayREACTOME_GLUTATHIONE_CONJUGATION

GGT1 GGT5

2.64e-0336302M1443
Pubmed

Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.

GGT2P GGT1 GGT3P GGT5

4.38e-11647412163373
Pubmed

Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.

GGT2P GGT1 GGT3P GGT5

4.38e-11647411463821
Pubmed

Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.

GGT2P GGT1 GGT3P

2.31e-0934732573352
Pubmed

The human gamma-glutamyltransferase gene family.

GGT2P GGT1 GGT3P GGT5

2.90e-091447418357469
Pubmed

Lung lining fluid glutathione attenuates IL-13-induced asthma.

GGT2P GGT1 GGT3P

2.31e-08547318063838
Pubmed

Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.

GGT2P GGT1 GGT3P

2.31e-08547310940879
Pubmed

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.

GGT2P GGT1 GGT3P

2.31e-08547328660214
Pubmed

Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.31e-08547312468440
Pubmed

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

GGT2P GGT1 GGT3P

2.31e-08547326977590
Pubmed

Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.

GGT2P GGT1 GGT3P

2.31e-08547312225953
Pubmed

Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.

GGT2P GGT1 GGT3P

2.31e-0854737775425
Pubmed

Cataract development in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.31e-08547311095909
Pubmed

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.

GGT2P GGT1 GGT3P

2.31e-0854737641802
Pubmed

Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.

GGT2P GGT1 GGT3P

2.31e-08547323615310
Pubmed

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

GGT2P GGT1 GGT3P

2.31e-0854738566783
Pubmed

Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.

GGT2P GGT1 GGT3P

2.31e-08547330591459
Pubmed

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

GGT2P GGT1 GGT3P

2.31e-0854739139708
Pubmed

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

GGT2P GGT1 GGT3P

2.31e-08547320622017
Pubmed

The mouse skin carcinogenesis model.

GGT2P GGT1 GGT3P

2.31e-0854739627710
Pubmed

Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.31e-0854739546365
Pubmed

Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.

GGT2P GGT1 GGT3P

2.31e-08547312453183
Pubmed

In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.

GGT2P GGT1 GGT3P

2.31e-08547311795900
Pubmed

gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?

GGT2P GGT1 GGT3P

2.31e-0854737485380
Pubmed

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.

GGT2P GGT1 GGT3P

2.31e-08547311003618
Pubmed

Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.

GGT2P GGT1 GGT3P

2.31e-08547310751614
Pubmed

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

GGT2P GGT1 GGT3P

2.31e-08547310392451
Pubmed

Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.

GGT2P GGT1 GGT3P

2.31e-0854737523374
Pubmed

Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.

GGT2P GGT1 GGT3P

2.31e-0854732891746
Pubmed

Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.

GGT2P GGT1 GGT3P

2.31e-08547324698228
Pubmed

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

GGT2P GGT1 GGT3P

2.31e-08547319850887
Pubmed

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.

GGT2P GGT1 GGT3P

2.31e-08547325132819
Pubmed

Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.

GGT2P GGT1 GGT3P

2.31e-08547319760322
Pubmed

gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.

GGT2P GGT1 GGT3P

2.31e-08547310474818
Pubmed

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.31e-08547312810527
Pubmed

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.31e-0854738755578
Pubmed

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.31e-08547311089562
Pubmed

Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.

GGT2P GGT1 GGT3P

4.61e-08647314634009
Pubmed

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.

GGT2P GGT1 GGT3P

4.61e-08647317363454
Pubmed

Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.

GGT2P GGT1 GGT3P

4.61e-0864738101000
Pubmed

Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.

GGT2P GGT1 GGT3P

4.61e-0864738663190
Pubmed

Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.

GGT2P GGT1 GGT3P

4.61e-0864738104871
Pubmed

Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

GGT2P GGT1 GGT3P

4.61e-08647322242126
Pubmed

Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.

GGT2P GGT1 GGT3P

4.61e-08647325326709
Pubmed

γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.

GGT2P GGT1 GGT3P

8.06e-08747327775020
Pubmed

Defective epidermal growth factor gene expression in mice with polycystic kidney disease.

GGT2P GGT1 GGT3P

8.06e-0874731968405
Pubmed

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

GGT2P GGT1 GGT3P

8.06e-08747332284594
Pubmed

m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.

GGT2P GGT1 GGT3P

8.06e-08747336685533
Pubmed

Direct reprogramming of fibroblasts into renal tubular epithelial cells by defined transcription factors.

EMX2 GGT2P GGT1 GGT3P

2.09e-073847427820600
Pubmed

Renalase regulates renal dopamine and phosphate metabolism.

GGT2P GGT1 GGT3P

2.76e-071047323863468
Pubmed

Mouse models of ocular diseases.

TYRP1 GGT2P GGT1 GGT3P

3.82e-074447416332269
Pubmed

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice.

GGT2P GGT1 GGT3P GGT5

1.02e-065647420096683
Pubmed

The asparaginyl hydroxylase factor inhibiting HIF-1alpha is an essential regulator of metabolism.

CA9 VHL VHLL

1.04e-061547320399150
Pubmed

The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high-energy phosphate metabolism.

VHL VHLL

1.79e-06247227422990
Pubmed

Deciphering von Hippel-Lindau (VHL/Vhl)-associated pancreatic manifestations by inactivating Vhl in specific pancreatic cell populations.

VHL VHLL

1.79e-06247219340311
Pubmed

Cancer. Many vessels, faulty gene.

VHL VHLL

1.79e-06247210353237
Pubmed

Clinical application value of hepatitis B virus basal core promoter 1762/1764 and GGTII and GGT in patients with HBV-DNA-positive primary liver cancer.

GGT2P GGT1

1.79e-06247237904480
Pubmed

Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor.

VHL VHLL

1.79e-06247211171994
Pubmed

The VHL tumor suppressor in development and disease: functional studies in mice by conditional gene targeting.

VHL VHLL

1.79e-06247215908240
Pubmed

Neuroprotective effects respond to cerebral ischemia without susceptibility to HB-tumorigenesis in VHL heterozygous knockout mice.

VHL VHLL

1.79e-06247228574654
Pubmed

Tubular deficiency of von Hippel-Lindau attenuates renal disease progression in anti-GBM glomerulonephritis.

VHL VHLL

1.79e-06247221925138
Pubmed

Deletion of Vhl in Dmp1-Expressing Cells Causes Microenvironmental Impairment of B Cell Lymphopoiesis.

VHL VHLL

1.79e-06247235250971
Pubmed

Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis.

VHL VHLL

1.79e-06247226488390
Pubmed

VHL loss reprograms the immune landscape to promote an inflammatory myeloid microenvironment in renal tumorigenesis.

VHL VHLL

1.79e-06247238618956
Pubmed

Gamma glutamyl transferase activity is independently associated with oxidative stress rather than SYNTAX score.

GGT2P GGT1

1.79e-06247225180444
Pubmed

Mediator kinase inhibition further activates super-enhancer-associated genes in AML.

CDK8 CDK19

1.79e-06247226416749
Pubmed

VHL Inactivation in Precancerous Kidney Cells Induces an Inflammatory Response via ER Stress-Activated IRE1α Signaling.

VHL VHLL

1.79e-06247228533271
Pubmed

Podocytes contribute to the formation of glomerular crescents.

VHL VHLL

1.79e-06247218199804
Pubmed

Molecular cloning of the von Hippel-Lindau tumor suppressor gene and its role in renal carcinoma.

VHL VHLL

1.79e-0624728603073
Pubmed

Endothelial function of von Hippel-Lindau tumor suppressor gene: control of fibroblast growth factor receptor signaling.

VHL VHLL

1.79e-06247218559510
Pubmed

Susceptibility to vascular neoplasms but no increased susceptibility to renal carcinogenesis in Vhl knockout mice.

VHL VHLL

1.79e-06247214604887
Pubmed

Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.

CDK8 CDK19

1.79e-06247232560467
Pubmed

Hypoxia and podocyte-specific Vhlh deletion confer risk of glomerular disease.

VHL VHLL

1.79e-06247217609290
Pubmed

CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.

CDK8 CDK19

1.79e-06247228855340
Pubmed

The VHL tumor suppressor and HIF: insights from genetic studies in mice.

VHL VHLL

1.79e-06247218219317
Pubmed

Loss of Vhl in cartilage accelerated the progression of age-associated and surgically induced murine osteoarthritis.

VHL VHLL

1.79e-06247224999110
Pubmed

Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.

CDK8 CDK19

1.79e-06247235181333
Pubmed

Acute inactivation of the VHL gene contributes to protective effects of ischemic preconditioning in the mouse kidney.

VHL VHLL

1.79e-06247218957870
Pubmed

Comparative sequence analysis of the VHL tumor suppressor gene.

VHL VHLL

1.79e-06247210857749
Pubmed

Pulmonary epithelial cancer cells and their exosomes metabolize myeloid cell-derived leukotriene C4 to leukotriene D4.

GGT1 GGT5

1.79e-06247227436590
Pubmed

pVHL and GSK3beta are components of a primary cilium-maintenance signalling network.

VHL VHLL

1.79e-06247217450132
Pubmed

Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling.

GGT2P GGT1

1.79e-06247223682772
Pubmed

Regulatory functions of the Mediator kinases CDK8 and CDK19.

CDK8 CDK19

1.79e-06247230585107
Pubmed

Vhl is required for normal pancreatic β cell function and the maintenance of β cell mass with age in mice.

VHL VHLL

1.79e-06247221242957
Pubmed

Cloning and characterization of a mouse gene with homology to the human von Hippel-Lindau disease tumor suppressor gene: implications for the potential organization of the human von Hippel-Lindau disease gene.

VHL VHLL

1.79e-0624727850784
Pubmed

Tumor suppressor VHL functions in the control of mitotic fidelity.

VHL VHLL

1.79e-06247224362914
Pubmed

Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes.

GGT1 GGT5

1.79e-06247221447318
Pubmed

A mouse model to study the link between hypoxia, long QT interval and sudden infant death syndrome.

VHL VHLL

1.79e-06247222977222
Pubmed

Decreased growth of Vhl-/- fibrosarcomas is associated with elevated levels of cyclin kinase inhibitors p21 and p27.

VHL VHLL

1.79e-06247215899860
Pubmed

Genetic and functional analysis of the von Hippel-Lindau (VHL) tumour suppressor gene promoter.

VHL VHLL

1.79e-06247212114475
Pubmed

Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation.

VHL VHLL

1.79e-06247235118061
Pubmed

Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis.

VHL VHLL

1.79e-0624728521303
Pubmed

Critical role of VHL/BICD2/STAT1 axis in crystal-associated kidney disease.

VHL VHLL

1.79e-06247237833251
Pubmed

Von Hippel-Lindau gene product directs cytokinesis: a new tumor suppressor function.

VHL VHLL

1.79e-06247221652636
Pubmed

Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.

CDK8 CDK19

1.79e-06247227678455
Pubmed

Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch.

VHL VHLL

1.79e-06247229467323
Pubmed

Immunolabeling of gamma-glutamyl transferase 5 in normal human tissues reveals that expression and localization differ from gamma-glutamyl transferase 1.

GGT1 GGT5

1.79e-06247225377544
Pubmed

Oncogenic Cell Tagging and Single-Cell Transcriptomics Reveal Cell Type-Specific and Time-Resolved Responses to Vhl Inactivation in the Kidney.

VHL VHLL

1.79e-06247238502859
Pubmed

HIV Transcription Is Independent of Mediator Kinases.

CDK8 CDK19

1.79e-06247231044597
Pubmed

CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.

CDK8 CDK19

1.79e-06247236006697
Pubmed

Cloning of the rat homologue of the von Hippel-Lindau tumor suppressor gene and its non-somatic mutation in rat renal cell carcinomas.

VHL VHLL

1.79e-0624727493907
InteractionGGTLC1 interactions

GGT2P GGT1 GGT5

5.03e-078433int:GGTLC1
InteractionGGT2P interactions

GGT2P GGT1

1.33e-053432int:GGT2P
InteractionGGT1 interactions

GGT2P GGT1 GGT5

2.01e-0525433int:GGT1
InteractionALCAM interactions

MPL CA9 CDC73 MRPL42

2.17e-0577434int:ALCAM
Cytoband9q22.33

TRIM14 NUTM2G

5.31e-04334729q22.33
CytobandEnsembl 112 genes in cytogenetic band chr22q11

GGT2P GGT1 GGT3P GGT5

8.95e-04419474chr22q11
CytobandEnsembl 112 genes in cytogenetic band chr9q22

NUTM2F TRIM14 NUTM2G

1.15e-03200473chr9q22
Cytoband22q11.23

GGT1 GGT5

1.37e-035347222q11.23
Cytoband1p36.21

PRAMEF33 PRAMEF10

1.93e-03634721p36.21
Cytoband19q13.43

ZNF444 ZNF530

3.63e-038747219q13.43
Cytoband22q11.21

GGT2P GGT3P

5.83e-0311147222q11.21
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT2P GGT1 GGT3P GGT5

5.00e-0913314564
GeneFamilyCyclin dependent kinases

CDK8 CDK19

9.01e-0426312496
GeneFamilyCyclins|Mediator complex

CDK8 CDK19

1.45e-03333121061
Drug5-hydroxytryptophol

AANAT LOXL3 GGT1 GGT5

1.54e-0642464CID000009061
Druggamma-Glutamylglutamate

MPL GGT1 GGT5

8.59e-0620463CID000092865
Drugdulofibrate

GGT1 GGT5

1.20e-053462CID000068812
Drug2-(glutathion-S-yl)hydroquinone

GGT1 GGT5

1.20e-053462CID000177871
DrugGlu-AMC

GGT1 GGT5

1.20e-053462CID000126296
Drug2-nor-LTD1

GGT1 GGT5

1.20e-053462CID006439851
Druggamma-glutamyl-3-carboxy-4-nitroanilide

GGT1 GGT5

1.20e-053462CID000104545
Drug2-bromo-3-(N-acetylcystein-S-yl)hydroquinone

GGT1 GGT5

1.20e-053462CID000130861
DrugAC1MLYZ1

GGT1 GGT5

2.39e-054462CID003277748
DrugAgaridoxin

GGT1 GGT5

2.39e-054462CID000162851
Drugformylcolchicine

GGT1 GGT5

2.39e-054462CID000630944
Drug2-propyltoluene

GGT1 GGT5

2.39e-054462CID000014091
DrugAC1L41R0

GGT1 GGT5

2.39e-054462CID000175821
Drugbeta-aminoglutaryl-L-alpha-aminobutyrate

GGT1 GGT5

2.39e-054462CID000191734
Drugleukotriene C3

GGT1 GGT5

2.39e-054462CID005214901
DrugAdenylyl Imidodiphosphate

PTGDR KIF1A

2.39e-054462ctd:D000266
DrugEHEN

VHL GGT1 GGT5

2.72e-0529463CID000025742
Drugglutamylphenylalanine

GGT1 GGT5

3.98e-055462CID000111299
Drug4-agtp

GGT1 GGT5

3.98e-055462CID000164283
Druggamma-Glu-gsh

GGT1 GGT5

3.98e-055462CID000129080
Drug4-hydroxymethylphenylhydrazine

GGT1 GGT5

5.96e-056462CID000135538
DrugGPNA

GGT1 GGT5

5.96e-056462CID000081732
Drugaminocatechol

GGT1 GGT5

5.96e-056462CID000151726
Drugalpha-aminomethylglutarate

GGT1 GGT5

8.33e-057462CID000191519
Drugiosimide

GGT1 GGT5

1.11e-048462CID000060911
Drugcumene

EXT2 LOXL3 CYP4B1

1.33e-0449463CID000007406
DrugBcdfg

GGT1 GGT5

1.42e-049462CID003036106
DrugGamma-glutamylglutamine

GGT1 GGT5

1.42e-049462CID000150914
Drugacetaminophen-glutathione

GGT1 GGT5

1.42e-049462CID000084001
DrugSubsporin C

GGT1 GGT5

1.42e-049462CID000151723
Drug2,3,5-(trigsyl)hq

GGT1 GGT5

1.78e-0410462CID003035059
DrugC.I. 337

RHBDL1 GGT1 GGT5

1.78e-0454463CID006331826
DrugAC1L2AH8

GGT1 GGT5

2.17e-0411462CID000017688
Druggludopa

GGT1 GGT5

2.17e-0411462CID000115303
Drugtyrosinate

MPL TYRP1 AANAT EMX2

2.26e-04148464CID000001153
Drugphylloerythrin

GGT1 GGT5

3.07e-0413462CID005480977
DrugS-oxalylglutathione

GGT1 GGT5

3.07e-0413462CID000168007
Druganthglutin

GGT1 GGT5

3.07e-0413462CID000125748
Drugdiphenaldehyde

GGT1 GGT5

3.07e-0413462CID000014585
Drugsporidesmin

GGT1 GGT5

3.07e-0413462CID000099596
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT2P GGT1 GGT3P

1.08e-077443DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT2P GGT1 GGT3P

1.72e-078443DOID:0050741 (biomarker_via_orthology)
Diseasedevelopmental and epileptic encephalopathy 87 (implicated_via_orthology)

CDK8 CDK19

2.17e-062442DOID:0112221 (implicated_via_orthology)
Diseasevon Hippel-Lindau disease (implicated_via_orthology)

VHL VHLL

2.17e-062442DOID:14175 (implicated_via_orthology)
Diseasefamilial erythrocytosis 2 (implicated_via_orthology)

VHL VHLL

2.17e-062442DOID:0060474 (implicated_via_orthology)
Diseasesudden infant death syndrome (implicated_via_orthology)

VHL VHLL

6.51e-063442DOID:9007 (implicated_via_orthology)
Diseasenephroblastoma (biomarker_via_orthology)

VHL VHLL

1.30e-054442DOID:2154 (biomarker_via_orthology)
Diseaseurinary bladder cancer (biomarker_via_orthology)

VHL VHLL

1.96e-0414442DOID:11054 (biomarker_via_orthology)
DiseaseCarcinoma of Endocrine Gland

VHL CDC73

2.25e-0415442C1704374
DiseaseParkinsonism (implicated_via_orthology)

VHL VHLL

8.60e-0429442DOID:0080855 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
YLFGWIHYRRGLVHL

PRAMEF33

166

A0A0G2JMD5
YSFRLHIGRNIARPW

TTF1

586

Q15361
RYHGPDWRIFHRLAL

ANTXRL

31

A6NF34
TFWYRAPELLLGARH

CDK19

196

Q9BWU1
YHKRHLDRPVFLRFW

CDC73

501

Q6P1J9
WRFLPEALFLHRAFH

ALG3

276

Q92685
PGREYRALQLHLHWG

CA9

216

Q16790
FPPRAHCLVRWYGLR

RAB3GAP1

111

Q15042
WLSLGHPFFYRRHIT

PTGDR

131

Q13258
YPLHYLVWHNRHREL

ANKRD13B

16

Q86YJ7
YELAHQRHGRLPWAR

GGT3P

141

A6NGU5
RSANWPYGHRRLLRF

LOXL3

566

P58215
ADGRHPRVFAWVYRH

FAM43B

151

Q6ZT52
FKHGIDRYWRRVAPH

IPO11

66

Q9UI26
RRRSFRGFWLTHHLY

DUOX2

1211

Q9NRD8
ALLFERAHYRHDPRW

MEI1

21

Q5TIA1
RGKVPGRAHRDWYHR

PTPMT1

26

Q8WUK0
VLHLHRREAVRWPYL

FRS3

46

O43559
GYAEAHRRHGRLPWA

GGT5

146

P36269
IYWLTPHGRRFLRAC

CYP4B1

236

P13584
PWLIHRYRYLGHRFQ

EMX2

121

Q04743
TFWYRAPELLLGARH

CDK8

196

P49336
YELAHQRHGRLPWAR

GGT2P

141

P36268
YLHFLEPHTSGWARR

KIF1A

1581

Q12756
LRWRYHALRGELYRP

PKD1

4106

P98161
YVVGSHHRLRPWRLS

NUTM2F

641

A1L443
YVVGSHHRLRPWRLS

NUTM2G

626

Q5VZR2
WRYLHHLGSQPAVRR

AANAT

141

Q16613
RAWREHGVRPLPYRH

LRRC56

386

Q8IYG6
LFWGHHPQRKRRGYS

INSL6

161

Q9Y581
IHNFRSHPWLFRDAR

VHLL

91

Q6RSH7
VYHPGHRARAWRFLT

RHBDL1

236

O75783
YLGEAHGPWVDLRRR

ZNF653

61

Q96CK0
EGPAFLTWHRYHLLR

TYRP1

216

P17643
LDSPWHRFRRFHLGD

ZNF444

16

Q8N0Y2
HRWYPHGRYHRCRKN

MRPL42

121

Q9Y6G3
DRLVGYPGRLHLWDH

EXT2

561

Q93063
GRRIHSYRGHLWLFR

VHL

106

P40337
AYGHRDRLPALAWLL

PRRT4

421

C9JH25
YLFGWIHYRRGLVHL

PRAMEF10

166

O60809
GQAFRLGRYPIHWHL

PKHD1L1

2466

Q86WI1
QFPAHYRRLRHALWP

MPL

516

P40238
YWAFHDGQRSRLRPR

TRIM14

371

Q14142
YHQRFGRPRWVDHKD

ZNF587B

371

E7ETH6
LFRHWRVHTGVRPYE

ZNF530

366

Q6P9A1
IPGRDHRRYYHDHWR

ZFTA

96

C9JLR9
YELAHQRHGRLPWAR

GGT1

141

P19440