Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OR8H3 OR8J2 OR5M10 TPRA1 OR9G1 OR2T27 OR4Q2 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR51J1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 NLRP6 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	1.66e-25	884	96	37	GO:0004930
GeneOntologyMolecularFunction	olfactory receptor activity	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	3.24e-24	431	96	28	GO:0004984
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OR8H3 OR8J2 OR5M10 TPRA1 IGSF6 OR9G1 OR2T27 OR4Q2 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR51J1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 NLRP6 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 ABCC8 TLR5 OR4K5 OR8G5 OSMR OR8D4 OR7G3 OR4K15 CNR1 OR9A2	4.00e-23	1353	96	41	GO:0004888
GeneOntologyMolecularFunction	odorant binding	OR8H3 OR8J2 OR5M10 OR9G1 OR14J1 OR8H1 OR5M11 OR8B8 OR8A1 OR8G5 OR8D4	2.48e-11	127	96	11	GO:0005549
GeneOntologyMolecularFunction	active transmembrane transporter activity	ABCC4 ABCA3 ATP7A SLC35C2 COX15 UQCR10 SLC12A4 SLC19A1 ABCC8 SLC45A1	9.91e-05	477	96	10	GO:0022804
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCC4 ABCA3 ATP7A COX15 UQCR10 ABCC8	2.20e-04	178	96	6	GO:0015399
GeneOntologyMolecularFunction	guanine nucleotide transmembrane transporter activity	ABCC4 SLC19A1	2.27e-04	5	96	2	GO:0001409
GeneOntologyMolecularFunction	xenobiotic transmembrane transporter activity	ABCC4 ABCA3 SLC19A1	5.78e-04	34	96	3	GO:0042910
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	ATP7A COX15 UQCR10 SLC12A4 SLC19A1 ABCC8 SLC45A1	6.26e-04	301	96	7	GO:0022853
GeneOntologyMolecularFunction	pattern recognition receptor activity	NLRP6 NOD2 TLR5	6.30e-04	35	96	3	GO:0038187
GeneOntologyMolecularFunction	transporter activity	ABCC4 ABCA3 ATP7A TMC1 SLC35C2 BEST3 COX15 NMUR2 UQCR10 SLC12A4 SLC19A1 ABCC8 SERINC3 SLC45A1 RFT1	1.21e-03	1289	96	15	GO:0005215
GeneOntologyMolecularFunction	transmembrane transporter activity	ABCC4 ABCA3 ATP7A TMC1 SLC35C2 BEST3 COX15 NMUR2 UQCR10 SLC12A4 SLC19A1 ABCC8 SERINC3 SLC45A1	1.49e-03	1180	96	14	GO:0022857
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCC4 ABCA3 ABCC8	1.69e-03	49	96	3	GO:0140359
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCC4 ABCA3 ATP7A ABCC8	1.90e-03	109	96	4	GO:0042626
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception of smell	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	1.45e-24	432	96	28	GO:0050911
GeneOntologyBiologicalProcess	sensory perception of smell	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	1.09e-23	465	96	28	GO:0007608
GeneOntologyBiologicalProcess	detection of chemical stimulus	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 NOD2 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	1.63e-23	524	96	29	GO:0009593
GeneOntologyBiologicalProcess	detection of chemical stimulus involved in sensory perception	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	3.45e-23	485	96	28	GO:0050907
GeneOntologyBiologicalProcess	sensory perception of chemical stimulus	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	5.44e-23	547	96	29	GO:0007606
GeneOntologyBiologicalProcess	detection of stimulus involved in sensory perception	OR8H3 OR8J2 OR5M10 TMC1 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	3.07e-22	582	96	29	GO:0050906
GeneOntologyBiologicalProcess	detection of stimulus	OR8H3 OR8J2 OR5M10 TMC1 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 NOD2 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	9.05e-21	722	96	30	GO:0051606
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR8H3 OR8J2 OR5M10 TPRA1 OR9G1 OR2T27 OR4Q2 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR51J1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 NLRP6 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	3.43e-19	1395	96	37	GO:0007186
GeneOntologyBiologicalProcess	sensory perception	OR8H3 OR8J2 OR5M10 TMC1 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	5.71e-17	1072	96	31	GO:0007600
GeneOntologyBiologicalProcess	xenobiotic transmembrane transport	ABCC4 ABCA3 SLC19A1	8.97e-05	19	96	3	GO:0006855
Domain	GPCR_Rhodpsn_7TM	OR8H3 OR5M10 OR9G1 OR2T27 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	4.40e-22	670	93	31	IPR017452
Domain	7tm_1	OR8H3 OR5M10 OR9G1 OR2T27 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	5.97e-22	677	93	31	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR8H3 OR5M10 OR9G1 OR2T27 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	8.44e-22	685	93	31	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR8H3 OR5M10 OR9G1 OR2T27 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	1.09e-21	691	93	31	PS50262
Domain	GPCR_Rhodpsn	OR8H3 OR5M10 OR9G1 OR2T27 GPR34 OR13C5 OR13F1 OR8S1 OR14J1 TAAR5 OR8H1 NMUR2 OR5M11 SUCNR1 OR6M1 GPR139 CCKBR OR9G9 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 CNR1 OR9A2	1.14e-21	692	93	31	IPR000276
Domain	Olfact_rcpt	OR8H3 OR5M10 OR9G1 OR2T27 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR6M1 OR9G9 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	8.16e-20	393	93	24	IPR000725
Domain	ABC_transporter_CS	ABCC4 ABCA3 ABCC8	1.19e-03	42	93	3	IPR017871
Domain	ABC_TRANSPORTER_2	ABCC4 ABCA3 ABCC8	1.76e-03	48	93	3	PS50893
Domain	ABC_tran	ABCC4 ABCA3 ABCC8	1.76e-03	48	93	3	PF00005
Domain	ABC_TRANSPORTER_1	ABCC4 ABCA3 ABCC8	1.87e-03	49	93	3	PS00211
Domain	ABC_transporter-like	ABCC4 ABCA3 ABCC8	1.98e-03	50	93	3	IPR003439
Domain	NACHT	NLRP6 NOD2	5.80e-03	23	93	2	PS50837
Domain	NACHT_NTPase	NLRP6 NOD2	5.80e-03	23	93	2	IPR007111
Domain	ABC_membrane	ABCC4 ABCC8	6.30e-03	24	93	2	PF00664
Domain	ABC_TM1F	ABCC4 ABCC8	8.52e-03	28	93	2	PS50929
Domain	ABC1_TM_dom	ABCC4 ABCC8	8.52e-03	28	93	2	IPR011527
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR8H3 OR8J2 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	5.52e-24	417	75	28	M4072
Pathway	REACTOME_SENSORY_PERCEPTION	OR8H3 OR8J2 OR5M10 TMC1 OR9G1 OR2T27 OR4Q2 OR13C5 PCLO OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR6M1 OR9G9 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	2.52e-21	636	75	30	M41834
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR8H3 OR5M10 OR9G1 OR2T27 OR13C5 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR6M1 OR8B8 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	2.31e-18	389	75	23	M14091
Pathway	WP_GPCRS_ODORANT	TPRA1 GPR34 TAAR5 GPR139 OR8B8 OR10D3 OR8A1 OR8G5	1.77e-06	157	75	8	MM15872
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	GPR34 SUCNR1 CCKBR OR8B8 OR8A1 OR8G5 CNR1	5.79e-05	186	75	7	MM15994
Pathway	WP_GPCRS_CLASS_A_RHODOPSINLIKE	GPR34 OR14J1 NMUR2 SUCNR1 CCKBR OR8B8 CNR1	4.57e-04	260	75	7	M39397
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR8H3 OR5M10 OR9G1 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	5.45e-24	340	97	22	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR8H3 OR5M10 OR9G1 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	5.45e-24	340	97	22	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR8H3 OR5M10 OR9G1 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	6.61e-24	343	97	22	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR8H3 OR5M10 OR9G1 OR13F1 OR8S1 OR14J1 OR8H1 OR5M11 OR51J1 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR2T6 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	8.00e-24	346	97	22	14611657
Pubmed	The human olfactory receptor gene family.	OR8H3 OR5M10 OR9G1 OR2T27 OR4Q2 OR13C5 OR13F1 OR14J1 OR8H1 OR5M11 OR6M1 OR8B8 OR10D3 OR51G2 OR8A1 OR2K2 OR51F2 OR4K5 OR8G5 OR8D4 OR7G3 OR4K15 OR9A2	6.30e-21	541	97	23	14983052
Pubmed	Natural selection on the olfactory receptor gene family in humans and chimpanzees.	OR8J2 OR6M1 OR51G2 OR9A2	1.32e-07	17	97	4	12908129
Pubmed	p300-mediated acetylation stabilizes the Th-inducing POK factor.	MYBBP1A PRPF8 ZBTB7B	4.18e-07	6	97	3	20810990
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR4Q2 OR5M11 OR6M1 OR8B8 OR8A1 OR2T6 OR7G3	2.83e-06	219	97	7	12213199
Pubmed	Specificity of olfactory receptor interactions with other G protein-coupled receptors.	OR8A1 OR8D4	7.70e-06	2	97	2	17472961
Pubmed	Regulation of Salmonella flagellin-induced interleukin-8 in intestinal epithelial cells by muramyl dipeptide.	NOD2 TLR5	7.70e-06	2	97	2	23121969
Pubmed	Microbial induction of CARD15 expression in intestinal epithelial cells via toll-like receptor 5 triggers an antibacterial response loop.	NOD2 TLR5	7.70e-06	2	97	2	16897777
Pubmed	Hypersensitivity of myelinated A-fibers via toll-like receptor 5 promotes mechanical allodynia in tenascin-X-deficient mice associated with Ehlers-Danlos syndrome.	TLR5 TNXB	7.70e-06	2	97	2	37898719
Pubmed	Association of polymorphous light eruption with NOD-2 and TLR-5 gene polymorphisms.	NOD2 TLR5	7.70e-06	2	97	2	35748133
Pubmed	Interaction between the cholecystokinin and endogenous cannabinoid systems in cued fear expression and extinction retention.	CCKBR CNR1	7.70e-06	2	97	2	25176168
Pubmed	The chromosomal distribution of mouse odorant receptor genes.	ZP2 OR8B8 OR8A1 OR8G5	1.62e-05	54	97	4	8570653
Pubmed	Ellis-van Creveld syndrome and profound deafness resulted by sequence variants in the EVC/EVC2 and TMC1 genes.	EVC2 TMC1	2.31e-05	3	97	2	29321360
Pubmed	A distinct pattern of disease-associated single nucleotide polymorphisms in IBD risk genes in a family with Crohn's disease.	NOD2 TLR5	2.31e-05	3	97	2	24901824
Pubmed	Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase.	SCD5 CNR1	2.31e-05	3	97	2	24191036
Pubmed	Microbiota-Dependent Hepatic Lipogenesis Mediated by Stearoyl CoA Desaturase 1 (SCD1) Promotes Metabolic Syndrome in TLR5-Deficient Mice.	SCD5 TLR5	2.31e-05	3	97	2	26525535
Pubmed	Novel NOD2 haplotype strengthens the association between TLR4 Asp299gly and Crohn's disease in an Australian population.	NOD2 TLR5	2.31e-05	3	97	2	18213697
Pubmed	Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.	ABCC4 ABCA3 SLC19A1	2.70e-05	21	97	3	23137377
Pubmed	Nod2 is required for antigen-specific humoral responses against antigens orally delivered using a recombinant Lactobacillus vaccine platform.	NOD2 TLR5	4.60e-05	4	97	2	29734365
Pubmed	Some cannabinoid receptor ligands and their distomers are direct-acting openers of SUR1 K(ATP) channels.	ABCC8 CNR1	4.60e-05	4	97	2	22167524
Pubmed	Genomic analysis of Meckel-Gruber syndrome in Arabs reveals marked genetic heterogeneity and novel candidate genes.	EVC2 CPLANE1	4.60e-05	4	97	2	23169490
Pubmed	Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16.	MUC16 TLR5	4.60e-05	4	97	2	25563498
Pubmed	Odorant and vomeronasal receptor genes in two mouse genome assemblies.	OR5M11 OR51F2 OR7G3 OR4K15	5.63e-05	74	97	4	15081110
Pubmed	ABC gene expression profiles have clinical importance and possibly form a new hallmark of cancer.	ABCA3 ABCC8	7.66e-05	5	97	2	28468577
Pubmed	Uroporphyrinogen-III synthase: molecular cloning, nucleotide sequence, expression of a mouse full-length cDNA, and its localization on mouse chromosome 7.	CYP2E1 ZP2	7.66e-05	5	97	2	7607680
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	FAM234B ABCA3 RTN3 SCD5 PRPF8 STT3B RFT1	8.95e-05	375	97	7	32788342
Pubmed	Mouse orthologs of human olfactory-like receptors expressed in the tongue.	OR8B8 OR2K2	1.15e-04	6	97	2	16859840
Pubmed	Mouse gastric mucin: cloning and chromosomal localization.	CYP2E1 ZP2	1.15e-04	6	97	2	7487932
Pubmed	Tenascin is induced at implantation sites in the mouse uterus and interferes with epithelial cell adhesion.	ZP2 TNXB	1.15e-04	6	97	2	7512897
Pubmed	The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota.	NOD2 TLR5	1.15e-04	6	97	2	35028606
Pubmed	Age-dependent enterocyte invasion and microcolony formation by Salmonella.	NOD2 TLR5	1.60e-04	7	97	2	25210785
Pubmed	Microarray analysis of hepatic gene expression identifies new genes involved in steatotic liver.	SCD5 CYP7B1	1.60e-04	7	97	2	19258494
Pubmed	Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects.	ABCC4 ABCA3 CYP2E1 ABCC8 CYP7B1	2.13e-04	193	97	5	19343046
Pubmed	Molecular characterization of Mybbp1a as a co-repressor on the Period2 promoter.	MYBBP1A DOCK7	2.13e-04	8	97	2	19129230
Pubmed	Molecular mapping of the tubby (tub) mutation on mouse chromosome 7.	ZP2 ABCC8	2.13e-04	8	97	2	8833147
Pubmed	Candidate gene association studies and risk of childhood acute lymphoblastic leukemia: a systematic review and meta-analysis.	CYP2E1 SLC19A1	2.13e-04	8	97	2	20511665
Pubmed	Different noses for different people.	OR8J2 OR4Q2	2.13e-04	8	97	2	12730696
Pubmed	Congenital Disorders of N-Linked Glycosylation and Multiple Pathway Overview	STT3B ALG8 RFT1	2.56e-04	44	97	3	20301507
Pubmed	Genetic mapping in human and mouse of the locus encoding TRBP, a protein that binds the TAR region of the human immunodeficiency virus (HIV-1).	CYP2E1 ZP2	2.74e-04	9	97	2	7774957
Pubmed	Plant Lectins Activate the NLRP3 Inflammasome To Promote Inflammatory Disorders.	NLRP6 NOD2	2.74e-04	9	97	2	28087670
Pubmed	Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome.	NOD2 TLR5	3.41e-04	10	97	2	22323544
Pubmed	Genome-wide association study of retinopathy in individuals without diabetes.	CYP7B1 PCDH18	3.41e-04	10	97	2	23393555
Pubmed	Characterization of a cluster comprising approximately 100 odorant receptor genes in mouse.	OR8B8 OR8G5	3.41e-04	10	97	2	11130974
Pubmed	IL-22BP is regulated by the inflammasome and modulates tumorigenesis in the intestine.	NLRP6 TLR5	4.17e-04	11	97	2	23075849
Pubmed	Non-canonical inflammasome activation targets caspase-11.	NLRP6 NOD2	4.99e-04	12	97	2	22002608
Pubmed	Maternal bile acid transporter deficiency promotes neonatal demise.	ABCC4 ABCA3 SCD5	6.10e-04	59	97	3	26416771
Pubmed	Polymorphisms of innate pattern recognition receptors, response to interferon-beta and development of neutralizing antibodies in multiple sclerosis patients.	NOD2 TLR5	6.85e-04	14	97	2	20595247
Pubmed	Molecular phylogenetics and the origins of placental mammals.	ATP7A CNR1	7.89e-04	15	97	2	11214319
Pubmed	High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes.	SCD5 CNR1	7.89e-04	15	97	2	18719666
Pubmed	LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.	ABCC4 SLC19A1	7.89e-04	15	97	2	28112518
Pubmed	Requirement for Slit-1 and Robo-2 in zonal segregation of olfactory sensory neuron axons in the main olfactory bulb.	OR8B8 OR8A1	9.01e-04	16	97	2	17715346
Pubmed	Olfactory receptors and signalling elements in the Grueneberg ganglion.	OR8H3 OR8H1	1.02e-03	17	97	2	16805845
Pubmed	Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.	NLRP6 TLR5	1.02e-03	17	97	2	22297845
Pubmed	Quantitative Protein Expression in the Human Retinal Pigment Epithelium: Comparison Between Apical and Basolateral Plasma Membranes With Emphasis on Transporters.	ABCC4 SLC19A1	1.14e-03	18	97	2	31791063
Pubmed	Requirement of FAT and DCHS protocadherins during hypothalamic-pituitary development.	DCHS2 EMCN	1.14e-03	18	97	2	33108146
Pubmed	Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.	CYP2E1 CYP7B1	1.28e-03	19	97	2	12721789
Pubmed	A novel common variant in DCST2 is associated with length in early life and height in adulthood.	ZBTB7B SPAG17	1.42e-03	20	97	2	25281659
Pubmed	Comparative Host Interactomes of the SARS-CoV-2 Nonstructural Protein 3 and Human Coronavirus Homologs.	COX15 STT3B DOCK7 ALG8 RFT1	1.47e-03	296	97	5	34186245
Pubmed	Regulation of the endosomal SNX27-retromer by OTULIN.	ABCC4 ATP7A	1.56e-03	21	97	2	31541095
Pubmed	Cholesterol 7α-hydroxylase-deficient mice are protected from high-fat/high-cholesterol diet-induced metabolic disorders.	SCD5 CYP7B1	1.71e-03	22	97	2	27146480
Pubmed	cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development.	ABCA3 M1AP	1.71e-03	22	97	2	21408140
Pubmed	Identification of 18 mouse ABC genes and characterization of the ABC superfamily in Mus musculus.	ABCA3 ABCC8	1.87e-03	23	97	2	10708515
Pubmed	Hypoxia inducible factor 3α plays a critical role in alveolarization and distal epithelial cell differentiation during mouse lung development.	ABCA3 SCD5	1.87e-03	23	97	2	23451260
Pubmed	Transcriptional programs controlling perinatal lung maturation.	ABCA3 SCD5	2.04e-03	24	97	2	22916088
Pubmed	Majority of cerebrospinal fluid-contacting neurons in the spinal cord of C57Bl/6N mice is present in ectopic position unlike in other studied experimental mice strains and mammalian species.	ZP2 OR51G2	2.04e-03	24	97	2	32212159
Pubmed	Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?	CYP2E1 CCKBR SLC12A4 ABCC8	2.09e-03	192	97	4	20602615
Pubmed	Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.	ABCA3 EMCN	2.22e-03	25	97	2	30604742
Pubmed	Expression of members of the putative olfactory receptor gene family in mammalian germ cells.	OR10D3 OR2K2	2.22e-03	25	97	2	1370859
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	MYBBP1A PRPF8 STT3B DOCK7	2.51e-03	202	97	4	33005030
Pubmed	Modulation of the combinatorial code of odorant receptor response patterns in odorant mixtures.	OR8H3 OR8H1	2.58e-03	27	97	2	32061665
Pubmed	Isolation of genes identified in mouse renal proximal tubule by comparing different gene expression profiles.	CYP2E1 SCD5 SERINC3	2.64e-03	98	97	3	9507200
Pubmed	Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.	MYBBP1A PRPF8	2.78e-03	28	97	2	19596686
Pubmed	Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.	ABCC4 PCLO STT3B SLC12A4 TMEM245 RFT1	2.79e-03	499	97	6	22810586
Cytoband	Ensembl 112 genes in cytogenetic band chr11q24	OR6M1 OR8B8 OR10D3 OR8A1 OR8G5 OR8D4 CDON	1.81e-07	191	97	7	chr11q24
Cytoband	11q24.2	OR8B8 OR10D3 OR8A1 OR8G5 CDON	2.42e-07	63	97	5	11q24.2
Cytoband	11q12.1	OR8H3 OR8J2 OR5M10 OR9G1 OR8H1 OR5M11	1.29e-06	161	97	6	11q12.1
Cytoband	Ensembl 112 genes in cytogenetic band chr11q12	OR8H3 OR8J2 OR5M10 OR9G1 OR8H1 OR5M11	9.59e-05	345	97	6	chr11q12
Cytoband	9q21.12	TMC1 MAMDC2	1.97e-04	10	97	2	9q21.12
Cytoband	Ensembl 112 genes in cytogenetic band chr9q31	OR13C5 OR13F1 OR2K2 TMEM245	2.12e-04	137	97	4	chr9q31
Cytoband	11p15.4	OR51J1 CCKBR OR51G2 OR51F2	8.83e-04	200	97	4	11p15.4
Cytoband	Ensembl 112 genes in cytogenetic band chr11p15	OR51J1 CCKBR NLRP6 OR51G2 OR51F2 ABCC8	1.29e-03	564	97	6	chr11p15
Cytoband	11q24.1	OR6M1 OR8D4	2.80e-03	37	97	2	11q24.1
Cytoband	9q31.1	OR13C5 OR13F1	3.43e-03	41	97	2	9q31.1
GeneFamily	Olfactory receptors, family 8	OR8H3 OR8J2 OR8S1 OR8H1 OR8B8 OR8A1 OR8G5 OR8D4	2.92e-11	49	77	8	155
GeneFamily	Olfactory receptors, family 9	OR9G1 OR9G9 OR9A2	1.24e-04	23	77	3	156
GeneFamily	Olfactory receptors, family 51	OR51J1 OR51G2 OR51F2	8.68e-04	44	77	3	164
GeneFamily	ATP binding cassette subfamily C	ABCC4 ABCC8	1.35e-03	13	77	2	807
GeneFamily	CD molecules\|Mucins	MUC16 EMCN	3.57e-03	21	77	2	648
GeneFamily	Olfactory receptors, family 13	OR13C5 OR13F1	4.27e-03	23	77	2	162
GeneFamily	NLR family	NLRP6 NOD2	5.04e-03	25	77	2	666
GeneFamily	Olfactory receptors, family 2	OR2T27 OR2K2 OR2T6	1.24e-02	113	77	3	149
Disease	congenital disorder of glycosylation type I (implicated_via_orthology)	ALG8 RFT1	8.80e-04	15	87	2	DOID:0050570 (implicated_via_orthology)
Disease	hepcidin:transferrin saturation ratio	MUC16 NLRP6	8.80e-04	15	87	2	EFO_0007902
Disease	food allergy measurement, parental genotype effect measurement	DCHS2 CYP7B1	1.28e-03	18	87	2	EFO_0005939, EFO_0007016
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	FAM234B GPR139	1.91e-03	22	87	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	Drug toxicity	ABCC4 CYP2E1 SLC19A1	1.99e-03	84	87	3	C0013221
Disease	Adverse reaction to drug	ABCC4 CYP2E1 SLC19A1	1.99e-03	84	87	3	C0041755
Disease	pseudotumor cerebri	OR9G1 OR9G9	2.67e-03	26	87	2	EFO_1001132

Protein segments in the cluster

Peptide	Gene	Start	Entry
SLLDFTLIYIQLSTS	nan	36	Q0VG73
YVNLTSLLIFRSVST	BEST3	131	Q8N1M1
TIYDTIATESTLFIR	CATSPERG	296	Q6ZRH7
TGVSILYTLTVSTAL	DISP3	1326	Q9P2K9
VSAATTLSLRLISDY	CSMD2	106	Q7Z408
SLFLVRLTTSLRITY	ARMH1	56	Q6PIY5
VRRTFSLDTILSSYL	FAM117A	86	Q9C073
KLLSTVLTTSYSVIF	GPR34	51	Q9UPC5
LLLLSFTYTALTIAR	ABCA3	266	Q99758
ASLSRLSYTTISTLG	CCKBR	431	P32239
SSVSVVLSSLFLKLY	ATP7A	1396	Q04656
TVTIFISYALILSSI	OR8B8	211	Q15620
VFQTTFFLTLLSLRT	OSMR	6	Q99650
TLSSSLFIILLSYLF	OR5M10	206	Q6IEU7
SYLFIITSVLRISSS	OR9G1	216	Q8NH87
LTSKLYSLLFRRTST	UQCR10	6	Q9UDW1
YSLLFRRTSTFALTI	UQCR10	11	Q9UDW1
LTLLYSTTLFLAREA	RFT1	51	Q96AA3
TETTSTTLRYGLLIL	CYP2E1	301	P05181
TYTILESFILGSSIT	PCDH18	501	Q9HCL0
ESFILGSSITTYVTI	PCDH18	506	Q9HCL0
LRLVYQITTSSESLS	MAMDC2	81	Q7Z304
SPYISTETITRLSTF	MUC16	5836	Q8WXI7
TSATSRSYSSIILPV	EMCN	181	Q9ULC0
SLTIIISYAFILTSI	OR8D4	211	Q8NGM9
SLTILSSYIFIIASI	OR8G5	246	Q8NG78
LSSSLTIVLVSYAFI	OR5M11	206	Q96RB7
STLRSTIAFAVFLIT	MCTP2	686	Q6DN12
TTRAALTYTSLEITI	M1AP	131	Q8TC57
VYSERSGLVLTSILT	MAG	461	P20916
FASILSITTVSVERY	NMUR2	131	Q9GZQ4
RFSKSLTETYVVITL	PCLO	2571	Q9Y6V0
SIVLSYIRIFSTVLR	OR14J1	211	Q9UGF5
FSVVTASYTRILITV	OR2T6	211	Q8NHC8
SYILIIRSVLSIASS	OR51F2	231	Q8NH61
FSYALILRTVLSIAS	OR51G2	221	Q8NGK0
TSTFGLDSLLIVISY	OR51J1	206	Q9H342
LSLSTFSLLVSSYII	OR4K5	206	Q8NGD3
LSLSSFLLLVVSYTV	OR4K15	206	Q8NH41
ISTISFVVLISSYTT	OR4Q2	206	P0C623
SSLVSYVRTSVFLLT	FAM234B	96	A2RU67
SRVTETLSAYTALLS	EVC2	976	Q86UK5
TLTTTIFLGTTYDAL	MT-ND1	236	P03886
TTYFVTKTLLLTSLF	MT-ND1	256	P03886
SIFILSLARILTAYS	GDPD4	31	Q6W3E5
ERSSLSLVSLVGTLY	KLHL40	546	Q2TBA0
FSVISGSYTRILITV	OR2T27	211	Q8NH04
VSYTLIILSIFKISS	OR13C5	216	Q8NGS8
SYLFIITSVLRISSS	OR9G9	216	P0C7N8
SVRAISVRTLYLVST	MROH1	461	Q8NDA8
TTGSYVYIISTILRI	OR6M1	211	Q8NGM8
VSTLILSSTSAYAVR	ODAD1	171	Q96M63
LNLVTRVYSTALSSF	MYBBP1A	971	Q9BQG0
LITISASYVSILSTI	OR8H3	211	Q8N146
SSLFTIDSTTGIIYL	DCHS2	816	Q6V1P9
SLTYLQSLITALTVS	OR8J2	146	Q8NGG1
FTTYVLLGSVITASR	ABCC4	336	O15439
LRSFLTALVSLLSVY	IGSF6	151	O95976
AITTLARSAIFSITY	DOCK7	321	Q96N67
YSLGTSLSRSTLTEL	CPLANE1	1451	Q9H799
LLYVTLTILCSSVSS	CDON	11	Q4KMG0
SETTTRISLLKAVFY	C1orf112	371	Q9NSG2
TTFRTITTDLLYVGS	CNR1	11	P21554
IFEALRLSSYSTTIR	CYP7B1	356	O75881
FYLILSTSGISIETT	ITGA7	806	Q13683
ITSVTAITVLYFLSR	COX15	331	Q7KZN9
TTAILFTITSIFATL	GPR139	226	Q6DWJ6
RVIYLFTAVTLSVTT	SLC45A1	301	Q9Y2W3
TSVYLLFITSVLSSA	NLRP6	416	P59044
TSLTVLVSYTFILSS	OR8A1	226	Q8NGG7
LVSYTFILSSILGIS	OR8A1	231	Q8NGG7
LSYTRITISILSIRT	OR10D3	216	Q8NH80
SLIPTIVSYTYIIST	OR9A2	206	Q8NGT5
ITISASYVSILSTIL	OR8H1	211	Q8NGG4
ISYAFILASILRISS	OR13F1	216	Q8NGS4
SYIFILSTILRITSA	OR2K2	216	Q8NGT1
LLSVTISFRIYKSVI	RTN3	886	O95197
TSLFLYTDVVETRLS	TAAR5	166	O14804
LSGIIFSYTRIVSSV	OR7G3	211	Q8NG95
LLYLVSSTLLTSLAV	SPPL2C	501	Q8IUH8
FLASILRYTISLNIS	SCD5	221	Q86SK9
ITLIATSLTSAYSTR	MT-ND5	411	P03915
LSYTRIISTILSISS	OR8S1	216	Q8NH09
ILAIITTSLVYFSSV	SLC12A4	456	Q9UP95
VQRTSTIYSSTLGVF	SPAG17	2201	Q6Q759
RLTVSDVLTTYVTIL	TMC1	526	Q8TDI8
TSLRAFAIYTSISIF	ABCC8	531	Q09428
LFTIYSISSLKTLFR	ALG8	436	Q9BVK2
TISSYTAFSRLILIL	PRPF8	1926	Q6P2Q9
VLAITTVLSLAYSVT	TPRA1	151	Q86W33
ALLEFAYTATLTTSS	ZBTB7B	101	O15156
LRTTVSAQSRFLSTY	NOD2	226	Q9HC29
TFSGLTSISTFLLTR	STT3B	176	Q8TCJ2
TVGRVSFSTLNYISL	SLC19A1	176	P41440
YALTSSLVLLVLLST	TNXB	6	P22105
FLLVSRTSSLTLSIA	SLC35C2	261	Q9NQQ7
SLSSYTCATRIITTL	SLC66A3	151	Q8N755
TVTRLIYAFILLLST	SERINC3	36	Q13530
LYTSILFLTFISIDR	SUCNR1	106	Q9BXA5
FLLTSVYGITLTLDT	ZDHHC23	311	Q8IYP9
TTVTTLLTILFYSGT	TMEM245	636	Q9H330
SLTLTYYRTAFLLST	ZNF286B	86	P0CG31
LLLSFNYIRTVTASS	TLR5	51	O60602
STYRSISLFFALVTS	ZP2	21	Q05996
ISLTSLYTDSCTRIL	WDR64	816	B1ANS9