Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	ATP2B1/4	ATP2B1 ATP2B4	3.13e-05	2	105	2	IPR030319
Domain	Talin-1	TLNRD1 TLN2	9.36e-05	3	105	2	IPR015710
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B4	1.86e-04	4	105	2	IPR022141
Domain	SHR-BD	VPS13C VPS13B	1.86e-04	4	105	2	IPR009543
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B4	1.86e-04	4	105	2	PF12424
Domain	VDCC_L_a1su	CACNA1C CACNA1S	1.86e-04	4	105	2	IPR005446
Domain	VPS13_C	VPS13C VPS13B	1.86e-04	4	105	2	PF16909
Domain	VPS13_C	VPS13C VPS13B	1.86e-04	4	105	2	IPR031645
Domain	P-type_ATPase_IIB	ATP2B1 ATP2B4	1.86e-04	4	105	2	IPR006408
Domain	SHR-BD	VPS13C VPS13B	1.86e-04	4	105	2	PF06650
Domain	Autophagy-rel_C	VPS13C VPS13B	3.10e-04	5	105	2	IPR015412
Domain	ATG_C	VPS13C VPS13B	3.10e-04	5	105	2	PF09333
Domain	ICAM_VCAM_N	ICAM5 VCAM1	4.63e-04	6	105	2	IPR003987
Domain	Ca_chan_IQ	CACNA1C CACNA1S	6.45e-04	7	105	2	SM01062
Domain	Ca_chan_IQ	CACNA1C CACNA1S	6.45e-04	7	105	2	PF08763
Domain	VDCC_a1su_IQ	CACNA1C CACNA1S	6.45e-04	7	105	2	IPR014873
Domain	GPHH	CACNA1C CACNA1S	6.45e-04	7	105	2	PF16905
Domain	GPHH_dom	CACNA1C CACNA1S	6.45e-04	7	105	2	IPR031649
Domain	Chorein_N	VPS13C VPS13B	8.57e-04	8	105	2	PF12624
Domain	VPS13_N	VPS13C VPS13B	8.57e-04	8	105	2	IPR026854
Domain	AAA	DNAH2 ABCB1 ABCA5 NAV3 ABCG5	1.32e-03	144	105	5	SM00382
Domain	AAA+_ATPase	DNAH2 ABCB1 ABCA5 NAV3 ABCG5	1.32e-03	144	105	5	IPR003593
Domain	S1	EXOSC1 PNPT1	1.37e-03	10	105	2	PS50126
Domain	VDCCAlpha1	CACNA1C CACNA1S	1.37e-03	10	105	2	IPR002077
Domain	Keratin_I	KRT14 KRT16 KRT35	1.93e-03	44	105	3	IPR002957
Domain	S1	EXOSC1 PNPT1	1.99e-03	12	105	2	SM00316
Domain	S1_dom	EXOSC1 PNPT1	1.99e-03	12	105	2	IPR022967
Domain	S1_domain	EXOSC1 PNPT1	1.99e-03	12	105	2	IPR003029
Domain	ABC_tran	ABCB1 ABCA5 ABCG5	2.49e-03	48	105	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCB1 ABCA5 ABCG5	2.49e-03	48	105	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCB1 ABCA5 ABCG5	2.64e-03	49	105	3	PS00211
Domain	ABC_transporter-like	ABCB1 ABCA5 ABCG5	2.79e-03	50	105	3	IPR003439
Domain	ATPase_P-typ_TM_dom	ATP2B1 ATP2B4	3.57e-03	16	105	2	IPR023298
Domain	-	ATP2B1 ATP2B4	3.57e-03	16	105	2	1.20.1110.10
Domain	Ion_trans_dom	CACNA1C CACNA1S TRPM4 KCNA10	3.92e-03	114	105	4	IPR005821
Domain	Ion_trans	CACNA1C CACNA1S TRPM4 KCNA10	3.92e-03	114	105	4	PF00520
Domain	ATPase_P-typ_cation-transptr_C	ATP2B1 ATP2B4	4.03e-03	17	105	2	IPR006068
Domain	Cation_ATPase_C	ATP2B1 ATP2B4	4.03e-03	17	105	2	PF00689
Domain	Channel_four-helix_dom	CACNA1C CACNA1S KCNA10	4.05e-03	57	105	3	IPR027359
Domain	-	CACNA1C CACNA1S KCNA10	4.05e-03	57	105	3	1.20.120.350
Domain	Cation_ATPase_N	ATP2B1 ATP2B4	4.52e-03	18	105	2	PF00690
Domain	Cation_ATPase_N	ATP2B1 ATP2B4	4.52e-03	18	105	2	SM00831
Domain	ATPase_P-typ_cation-transptr_N	ATP2B1 ATP2B4	5.03e-03	19	105	2	IPR004014
Domain	Intermediate_filament_CS	KRT14 KRT16 KRT35	5.37e-03	63	105	3	IPR018039
Pubmed	High-throughput microarray detection of olfactory receptor gene expression in the mouse.	OR2M7 OR2M2 OR2M5 OR2M3	9.47e-11	4	110	4	15377787
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	NR2C1 WAPL POLR1A VPS13C TUT7 MPDZ HMGCR PDLIM5 SGPL1 SEC16A ELP4 ANKS1A	3.75e-06	733	110	12	34672954
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	ARHGAP32 VPS13C ADGRB2 ADGRV1 SLC25A25 SGPL1 IQSEC1 USP12 ATP2B1	9.59e-06	430	110	9	32581705
Pubmed	Temporal expression of calcium channel subunits in satellite cells and bone marrow mesenchymal cells.	CACNA1C CACNA1S	9.91e-06	2	110	2	25277766
Pubmed	Correlation of induction of ATP binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor.	ABCB1 ABCA5	9.91e-06	2	110	2	17541169
Pubmed	Functional and structural demonstration of the presence of Ca-ATPase (PMCA) in both microvillous and basal plasma membranes from syncytiotrophoblast of human term placenta.	ATP2B1 ATP2B4	9.91e-06	2	110	2	18657858
Pubmed	A single nucleotide deletion in the skeletal muscle-specific calcium channel transcript of muscular dysgenesis (mdg) mice.	CACNA1C CACNA1S	9.91e-06	2	110	2	1281468
Pubmed	The functional diversity of epidermal keratins revealed by the partial rescue of the keratin 14 null phenotype by keratin 16.	KRT14 KRT16	9.91e-06	2	110	2	10477769
Pubmed	The influence of membrane lipid structure on plasma membrane Ca2+ -ATPase activity.	ATP2B1 ATP2B4	9.91e-06	2	110	2	16412504
Pubmed	Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.	ATP2B1 ATP2B4	9.91e-06	2	110	2	16956963
Pubmed	Localization of two genes encoding plasma membrane Ca2(+)-transporting ATPases to human chromosomes 1q25-32 and 12q21-23.	ATP2B1 ATP2B4	9.91e-06	2	110	2	1674727
Pubmed	Endogenous cardiac Ca2+ channels do not overcome the E-C coupling defect in immortalized dysgenic muscle cells: evidence for a missing link.	CACNA1C CACNA1S	9.91e-06	2	110	2	7635187
Pubmed	Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.	ATP2B1 ATP2B4	9.91e-06	2	110	2	15178683
Pubmed	REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer.	ABCB1 DKK3	9.91e-06	2	110	2	18654608
Pubmed	Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.	ATP2B1 ATP2B4	9.91e-06	2	110	2	16291816
Pubmed	Regulation of plasma membrane Ca2+-ATPase by small GTPases and phosphoinositides in human platelets.	ATP2B1 ATP2B4	9.91e-06	2	110	2	10748016
Pubmed	Selective upregulation of the expression of plasma membrane calcium ATPase isoforms upon differentiation and 1,25(OH)2D3-vitamin treatment of colon cancer cells.	ATP2B1 ATP2B4	9.91e-06	2	110	2	26116539
Pubmed	[Mechanisms of drug resistance and reversal of the resistance].	ABCB1 SLC22A18	9.91e-06	2	110	2	11925925
Pubmed	Plasma membrane calcium ATPase regulates bone mass by fine-tuning osteoclast differentiation and survival.	ATP2B1 ATP2B4	9.91e-06	2	110	2	23266958
Pubmed	cDNA cloning, expression, and assembly characteristics of mouse keratin 16.	KRT14 KRT16	9.91e-06	2	110	2	9822705
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	ARHGAP32 ADAM9 ADGRB2 MPDZ IQSEC1 TLN2 ANKS1A	1.59e-05	251	110	7	27507650
Pubmed	Sorcin associates with the pore-forming subunit of voltage-dependent L-type Ca2+ channels.	CACNA1C CACNA1S	2.97e-05	3	110	2	9668070
Pubmed	Angiotensin II suppresses long-term depression in the lateral amygdala of mice via L-type calcium channels.	CACNA1C CACNA1S	2.97e-05	3	110	2	17289261
Pubmed	Effects of CYP3A5, MDR1 and CACNA1C polymorphisms on the oral disposition and response of nimodipine in a Chinese cohort.	CACNA1C ABCB1	2.97e-05	3	110	2	19205682
Pubmed	Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20.	WDR20 USP12	2.97e-05	3	110	2	27373336
Pubmed	Keratin and filaggrin expression in keratoacanthoma.	KRT14 KRT16	2.97e-05	3	110	2	18005116
Pubmed	Impairment of hippocampal gamma-frequency oscillations in vitro in mice overexpressing human amyloid precursor protein (APP).	CACNA1C CACNA1S	2.97e-05	3	110	2	17767505
Pubmed	Dickkopf Homolog 3 Induces Stem Cell Differentiation into Smooth Muscle Lineage via ATF6 Signalling.	MYOCD DKK3	2.97e-05	3	110	2	26105053
Pubmed	A complex of Neuroplastin and Plasma Membrane Ca2+ ATPase controls T cell activation.	ATP2B1 ATP2B4	2.97e-05	3	110	2	28827723
Pubmed	Triad proteins and intracellular Ca2+ transients during development of human skeletal muscle cells in aneural and innervated cultures.	CACNA1C CACNA1S	2.97e-05	3	110	2	11206130
Pubmed	Molecular diversity of L-type calcium channels. Evidence for alternative splicing of the transcripts of three non-allelic genes.	CACNA1C CACNA1S	2.97e-05	3	110	2	2173707
Pubmed	mRNA for cardiac calcium channel is expressed during development of skeletal muscle.	CACNA1C CACNA1S	2.97e-05	3	110	2	8381753
Pubmed	Plasma membrane Ca2+ ATPase 1 (PMCA1) but not PMCA4 is critical for B-cell development and Ca2+ homeostasis in mice.	ATP2B1 ATP2B4	2.97e-05	3	110	2	33098669
Pubmed	The androgen metabolite, 5α-androstane-3β,17β-diol, decreases cytokine-induced cyclooxygenase-2, vascular cell adhesion molecule-1 expression, and P-glycoprotein expression in male human brain microvascular endothelial cells.	ABCB1 VCAM1	2.97e-05	3	110	2	23117931
Pubmed	A group of type I keratin genes on human chromosome 17: characterization and expression.	KRT14 KRT16	2.97e-05	3	110	2	2451124
Pubmed	Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle.	KRT14 KRT16	2.97e-05	3	110	2	12445204
Pubmed	Onset of re-epithelialization after skin injury correlates with a reorganization of keratin filaments in wound edge keratinocytes: defining a potential role for keratin 16.	KRT14 KRT16	2.97e-05	3	110	2	8636216
Pubmed	CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.	ATP2B1 ATP2B4	2.97e-05	3	110	2	15133509
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KIAA0232 ADAM9 HEATR5A SLC25A25 SEC16A NAV3 ULK1 VPS13B	4.76e-05	407	110	8	12693553
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ARHGAP32 ADAM9 KIF21A ADGRB2 MPDZ LZTS1 ICAM5 SEC16A IQSEC1 TLN2 ATP2B4 ANKS1A	5.55e-05	963	110	12	28671696
Pubmed	Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients.	HMGCR ABCB1 C2 ABCG5	5.87e-05	66	110	4	20679960
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B1 ATP2B4	5.92e-05	4	110	2	12209837
Pubmed	Analysis of the human VPS13 gene family.	VPS13C VPS13B	5.92e-05	4	110	2	15498460
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B1 ATP2B4	5.92e-05	4	110	2	12784250
Pubmed	Ubiquitin-specific protease 12 interacting partners Uaf-1 and WDR20 are potential therapeutic targets in prostate cancer.	WDR20 USP12	5.92e-05	4	110	2	26462181
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B1 ATP2B4	5.92e-05	4	110	2	15101689
Pubmed	Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.	CACNA1C CACNA1S	5.92e-05	4	110	2	20937870
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B1 ATP2B4	5.92e-05	4	110	2	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B4	5.92e-05	4	110	2	8245032
Pubmed	WDR20 prevents hepatocellular carcinoma senescence by orchestrating the simultaneous USP12/46-mediated deubiquitination of c-Myc.	WDR20 USP12	5.92e-05	4	110	2	39432777
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B1 ATP2B4	5.92e-05	4	110	2	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B1 ATP2B4	5.92e-05	4	110	2	8634322
Pubmed	The dystrophia myotonica WD repeat-containing protein DMWD and WDR20 differentially regulate USP12 deubiquitinase.	WDR20 USP12	5.92e-05	4	110	2	33844468
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B4	5.92e-05	4	110	2	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B1 ATP2B4	5.92e-05	4	110	2	11152753
Pubmed	The sarcolemmal calcium pump, alpha-1 syntrophin, and neuronal nitric-oxide synthase are parts of a macromolecular protein complex.	ATP2B1 ATP2B4	5.92e-05	4	110	2	16735509
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B1 ATP2B4	5.92e-05	4	110	2	36130203
Pubmed	Ca2+ Homeostasis by Plasma Membrane Ca2+ ATPase (PMCA) 1 Is Essential for the Development of DP Thymocytes.	ATP2B1 ATP2B4	5.92e-05	4	110	2	36674959
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B1 ATP2B4	5.92e-05	4	110	2	10434059
Pubmed	WDR20 regulates shuttling of the USP12 deubiquitinase complex between the plasma membrane, cytoplasm and nucleus.	WDR20 USP12	5.92e-05	4	110	2	30466959
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ARHGAP32 ERICH5 ZFYVE9 WDR20 SEC16A USP12 ATP2B1 ATP2B4	6.03e-05	421	110	8	36976175
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	KIAA0232 SPAG9 ADGRV1 ZNF518A SEC16A TLN2	8.39e-05	225	110	6	12168954
Pubmed	WDR20 regulates activity of the USP12 x UAF1 deubiquitinating enzyme complex.	WDR20 USP12	9.85e-05	5	110	2	20147737
Pubmed	Changes in keratin and filaggrin expression in the skin of chronic proliferative dermatitis (cpdm) mutant mice.	KRT14 KRT16	9.85e-05	5	110	2	9873228
Pubmed	A combination of proatherogenic single-nucleotide polymorphisms is associated with increased risk of coronary artery disease and myocardial infarction in Asian Indians.	HMGCR ABCB1	9.85e-05	5	110	2	19558216
Pubmed	Increased maternofetal calcium flux in parathyroid hormone-related protein-null mice.	ATP2B1 ATP2B4	9.85e-05	5	110	2	18258656
Pubmed	Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.	ATP2B1 ATP2B4	9.85e-05	5	110	2	17938178
Pubmed	The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis.	SEC16A ULK1	9.85e-05	5	110	2	27203176
Pubmed	Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.	KRT14 KRT16	9.85e-05	5	110	2	2458356
Pubmed	The gene for the alpha 1 subunit of the skeletal muscle dihydropyridine-sensitive calcium channel (Cchl1a3) maps to mouse chromosome 1.	CACNA1C CACNA1S	9.85e-05	5	110	2	1335956
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARHGAP32 KRT14 KRT16 SPAG9 PTPN2 ZFYVE9 WDR20 SEC16A USP12 ATP2B1 KDM6A ATP2B4	1.24e-04	1049	110	12	27880917
Pubmed	Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.	KRT14 KRT16	1.47e-04	6	110	2	16702408
Pubmed	Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.	ATP2B1 ATP2B4	1.47e-04	6	110	2	12763866
Pubmed	Deubiquitinating enzyme Usp12 regulates the interaction between the androgen receptor and the Akt pathway.	WDR20 USP12	1.47e-04	6	110	2	25216524
Pubmed	Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection.	WDR20 USP12	1.47e-04	6	110	2	37289831
Pubmed	Common variants of HMGCR, CETP, APOAI, ABCB1, CYP3A4, and CYP7A1 genes as predictors of lipid-lowering response to atorvastatin therapy.	HMGCR ABCB1	1.47e-04	6	110	2	20578904
Pubmed	ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.	CACNA1C ATP2B1	1.47e-04	6	110	2	16352659
Pubmed	Common genetic variation in six lipid-related and statin-related genes, statin use and risk of incident nonfatal myocardial infarction and stroke.	HMGCR ABCB1	1.47e-04	6	110	2	18622260
Pubmed	Genetic predictors of depressive symptoms in cardiac patients.	CACNA1C VCAM1	1.47e-04	6	110	2	18618671
Pubmed	Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.	ATP2B1 ATP2B4	1.47e-04	6	110	2	12767889
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	GLS2 ADGRB2 ATP2B1 ATP2B4	1.50e-04	84	110	4	15123239
Pubmed	An investigation into the human serum "interactome".	KRT14 SETX KRT16 KIAA0232 TLN2	1.70e-04	162	110	5	15174051
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ARHGAP32 KRT14 KRT16 ACO2 ARPC1B PDLIM5 LZTS1 ICAM5 SGPL1 SEC16A IQSEC1 TLN2 ATP2B1 ATP2B4	1.72e-04	1431	110	14	37142655
Pubmed	Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.	CACNA1C CACNA1S	2.06e-04	7	110	2	12900400
Pubmed	The chromatin remodeling factor CSB recruits histone acetyltransferase PCAF to rRNA gene promoters in active state for transcription initiation.	ERCC6 POLR1A	2.06e-04	7	110	2	23667505
Pubmed	Differentiation and integrity of cardiac muscle cells are impaired in the absence of beta 1 integrin.	CACNA1C CACNA1S	2.06e-04	7	110	2	9004034
Pubmed	POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters.	ATP2B1 ATP2B4	2.06e-04	7	110	2	22084111
Pubmed	Characterization of WDR20: A new regulator of the ERAD machinery.	WDR20 USP12	2.06e-04	7	110	2	29655804
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	CACNA1C ATP2B1 ATP2B4	2.40e-04	38	110	3	30786075
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	DOCK1 CACNA1C TRPM4 POLR1A VPS13C KIAA0232 ADGRV1 THAP4 TRMT13 MCTP2 ATP2B1 KDM6A VPS13B ANKS1A	2.58e-04	1489	110	14	28611215
Pubmed	Identification of trichoplein, a novel keratin filament-binding protein.	KRT14 KRT16	2.74e-04	8	110	2	15731013
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2B1 ATP2B4	2.74e-04	8	110	2	10951186
Pubmed	The USP1-UAF1 complex interacts with RAD51AP1 to promote homologous recombination repair.	WDR20 USP12	2.74e-04	8	110	2	27463890
Pubmed	Comparative analysis of the expression of cytokeratins (1, 10, 14, 16, 4), involucrin, filaggrin and e-cadherin in plane warts and epidermodysplasia verruciformis plane wart-type lesions.	KRT14 KRT16	2.74e-04	8	110	2	19515043
Pubmed	Cytokeratin, vimentin and E-cadherin immunodetection in the embryonic palate in two strains of mice with different susceptibility to glucocorticoid-induced clefting.	KRT14 KRT16	2.74e-04	8	110	2	11321598
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ARHGAP32 TESPA1 IQSEC1 ULK1	3.05e-04	101	110	4	9872452
Pubmed	Identification of genetic variants associated with response to statin therapy.	HMGCR ABCB1	3.52e-04	9	110	2	19667110
Pubmed	International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.	CACNA1C CACNA1S	3.52e-04	9	110	2	16382099
Pubmed	Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.	WDR20 USP12	3.52e-04	9	110	2	21183687
Pubmed	Calcineurin-independent regulation of plasma membrane Ca2+ ATPase-4 in the vascular smooth muscle cell cycle.	ATP2B1 ATP2B4	3.52e-04	9	110	2	12660151
Interaction	ARL5B interactions	KRT14 VPS13C SPAG9 HMGCR GRPR VPS13B	3.16e-06	79	103	6	int:ARL5B
Interaction	SYNGAP1 interactions	DOCK1 ARHGAP32 ACO2 ADAM9 ADGRB2 MPDZ PDLIM5 IQSEC1 ULK1 ANKS1A	3.93e-06	307	103	10	int:SYNGAP1
Interaction	OR6C4 interactions	OR6C4 ST6GALNAC4	2.59e-05	2	103	2	int:OR6C4
Interaction	PTPRN2 interactions	KRT14 KRT16 ADGRV1 PTPN2 ATP2B1	3.61e-05	73	103	5	int:PTPRN2
Cytoband	1q44	OR2M7 OR2M2 OR2M5 OR2M3	1.48e-04	110	110	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2M7 OR2M2 OR2M5 OR2M3	2.65e-04	128	110	4	chr1q44
GeneFamily	Keratins, type I	KRT14 KRT16 KRT35	1.92e-04	28	73	3	608
GeneFamily	ATPases Ca2+ transporting	ATP2B1 ATP2B4	5.68e-04	9	73	2	1209
GeneFamily	Olfactory receptors, family 2	OR2M7 OR2M2 OR2M5 OR2M3	1.13e-03	113	73	4	149
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 TESPA1 ABCA5 LZTS1 PNCK RNF122 MCTP2	2.51e-07	173	110	7	4f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCell	droplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARHGAP32 TESPA1 ABCA5 LZTS1 PNCK RNF122 MCTP2	2.51e-07	173	110	7	9bbea566964281f47bf75d665b7d69ba8326e207
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ARHGAP32 ADGRB2 LZTS1 ICAM5 ATP2B1 ATP2B4 DKK3	4.10e-07	186	110	7	56c139e679d640ea901ead657a8e8887e0fca098
ToppCell	droplet-Thymus-nan-18m-Myeloid-Plasma_cells_and_B_cells\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S FAM185A LCORL ABCB1 ABCA5 C2	6.29e-06	183	110	6	ffb1bbbccb34d1a7e99872611f497450039d5019
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 XIRP2 ADAMTS16 NAV3 TLN2 MYOCD	6.49e-06	184	110	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	ADGRB2 LZTS1 ICAM5 ATP2B1 ATP2B4 DKK3	6.49e-06	184	110	6	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 XIRP2 ADAMTS16 NAV3 TLN2 MYOCD	6.49e-06	184	110	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRV1 XIRP2 ADAMTS16 NAV3 TLN2 MYOCD	6.49e-06	184	110	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	MPDZ MFAP2 C2 TLN2 PID1 VCAM1	7.80e-06	190	110	6	ec0ab31266583a0966ac7615d5c0fabb7b7e66e8
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C ADAMTS16 NAV3 TLN2 DKK3 VCAM1	8.28e-06	192	110	6	67e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA1C KIF21A PDLIM5 XIRP2 MYOCD ATP2B4	8.53e-06	193	110	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WAPL TUT7 SPAG9 MFAP2 PER3 ATP2B1	8.78e-06	194	110	6	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA1C KIF21A PDLIM5 XIRP2 MYOCD ATP2B4	9.04e-06	195	110	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C KIF21A HMGCR ABCA5 SEC16A ATP2B1	9.04e-06	195	110	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Mast\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TESPA1 ABCB1 PTPN2 SLC18A2 C2	4.84e-05	160	110	5	6393e3d5c5c8176c93aecd89b313bd054a00d474
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Mast-Mast_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TESPA1 ABCB1 PTPN2 SLC18A2 C2	4.84e-05	160	110	5	2065938e944eb99478fd8132c2c03adeaee6d447
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	LZTS1 ICAM5 ATP2B1 ATP2B4 DKK3	5.29e-05	163	110	5	218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCell	droplet-Liver-Npc-18m-Myeloid-plasmacytoid_dendritic_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 TESPA1 ABCA5 PNCK MCTP2	5.93e-05	167	110	5	1248f809afbcccb42ce9e29cfe6fa1f6f6b65005
ToppCell	TCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic\|TCGA-Mesothelium / Sample_Type by Project: Shred V9	ZNF469 LZTS1 NAV3 RNF122 PID1	5.93e-05	167	110	5	9062577a4b7902c9a888d706589d1b05221c0fa8
ToppCell	droplet-Liver-Npc-18m-Myeloid-plasmacytoid_dendritic_cells\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBPL2 TESPA1 ABCA5 PNCK MCTP2	5.93e-05	167	110	5	a66552667aa6e8992c159df27a57c2e8ae14a9ce
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C ARHGAP32 LZTS1 MCTP2 DKK3	6.45e-05	170	110	5	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	ileum\|World / shred on tissue and cell subclass	ACO2 ABCB1 SLC22A18 TKFC ABCG5	6.45e-05	170	110	5	9f1211bd4287620e19a59f21e6ecdca3e42e0260
ToppCell	367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	C16orf74 ABCB1 MCTP2 DKK3 VCAM1	7.01e-05	173	110	5	5d3c917e4d0de3158550a8ab2006ddfa87159ffa
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLS2 KIF21A TKFC ULK1 ABCG5	7.40e-05	175	110	5	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C PDLIM5 XIRP2 MYOCD ATP2B4	7.60e-05	176	110	5	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-late_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1S ERCC6 PIGZ TLN2 RNF122	7.60e-05	176	110	5	2e9073166da4d9fae70ba4f3fdcad35523caf7cd
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TESPA1 LZTS1 ICAM5 ADAMTS16 ATP2B4	7.60e-05	176	110	5	c7be4eaa5eb76ad9389fb9d15ad0934e88d267d1
ToppCell	facs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 NAV3 C2 DKK3 VCAM1	8.45e-05	180	110	5	12537d8a569faa69f474284d2c201475722b8ca1
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ARHGAP32 ADGRB2 LZTS1 ICAM5 DKK3	8.67e-05	181	110	5	58f76bb9ea1518c2b629a0256a3f6595a9278152
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	CACNA1C PDLIM5 XIRP2 MYOCD ATP2B4	8.90e-05	182	110	5	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	COVID-19-Heart-CM_4\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CACNA1C KIF21A XIRP2 MYOCD RNF122	9.13e-05	183	110	5	2902b6e8aa9a6f62bc1a792c971ab7f651a8e676
ToppCell	3'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KDM4E LCT ABCB1 TKFC ABCG5	9.37e-05	184	110	5	ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell	Posterior_cortex-Neuronal-Excitatory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	ARHGAP32 ADGRB2 LZTS1 ICAM5 ATP2B1	9.37e-05	184	110	5	25ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCell	LPS_only\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PPA1 PTPN2 RNF122 VPS13B VCAM1	9.61e-05	185	110	5	a72ccb147ca505880e2da8f6a70b9d570464a691
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C MFAP2 MYOCD PID1 DKK3	9.86e-05	186	110	5	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|(2)_5-FU / Stress and Cell class	MFAP2 PER3 C2 TLN2 PID1	1.01e-04	187	110	5	6bbf0f7fe203274dae8d582652f35cd3187c0065
ToppCell	Hippocampus-Neuronal-Excitatory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ADGRB2 LZTS1 ICAM5 ATP2B1 DKK3	1.06e-04	189	110	5	4b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	CACNA1C PDLIM5 XIRP2 MYOCD ATP2B4	1.06e-04	189	110	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CACNA1C MFAP2 MYOCD MCTP2 DKK3	1.06e-04	189	110	5	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	IPF-Epithelial-Basal\|Epithelial / Disease state, Lineage and Cell class	KRT14 KRT16 C16orf74 PID1 DKK3	1.09e-04	190	110	5	4f15842b424eefadbfe451875e517cf70e29607f
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	CACNA1C PDLIM5 XIRP2 MYOCD ATP2B4	1.09e-04	190	110	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	tumor_Lung-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	TRPM4 GLS2 KIF21A TESPA1 SLC18A2	1.09e-04	190	110	5	58a6ab70737d719ca9725ac087f20dfe9be0463e
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	CACNA1C ACO2 KIF21A PDLIM5 MYOCD	1.12e-04	191	110	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	(5)_Epi_basal\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	KRT14 ARPC1B MFAP2 CLDN20 DKK3	1.12e-04	191	110	5	6bda3d5a8a391d41bb4d65872492e6c094bcc4d4
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|(0)_Normal/No_Treatment / Stress and Cell class	MPDZ MFAP2 TLN2 PID1 VCAM1	1.14e-04	192	110	5	7a2ad0bdae647b88e799e62767605f2f3c5a426f
ToppCell	(1)_Control_(PBS)-(3)_LEPR+_perivascular_cells\|(1)_Control_(PBS) / Stress and Cell class	MPDZ MFAP2 C2 TLN2 PID1	1.14e-04	192	110	5	40f380f5f0bed63a7404be050838ebd01ef08987
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|World / Stress and Cell class	MPDZ MFAP2 C2 TLN2 VCAM1	1.17e-04	193	110	5	f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	LCORL KIF21A HEATR5A ADGRV1 VPS13B	1.17e-04	193	110	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	COVID-19-Fibroblasts-Other_FB\|COVID-19 / group, cell type (main and fine annotations)	CACNA1C NAV3 TLN2 PID1 DKK3	1.17e-04	193	110	5	e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNA1C ADAMTS16 NAV3 MYOCD DKK3	1.17e-04	193	110	5	5de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	HEATR5A ADGRV1 PDLIM5 PID1 VCAM1	1.20e-04	194	110	5	7c6c0376603e5fcb64814fd6204d153629c2fbf5
ToppCell	facs-Bladder-nan-18m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 C2 RNF122 DKK3 VCAM1	1.20e-04	194	110	5	f4c9fc53ae31d58096906d9305b0b4082512a7e9
ToppCell	facs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MFAP2 C2 RNF122 DKK3 VCAM1	1.23e-04	195	110	5	18b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VPS13C KIF21A HMGCR SEC16A ATP2B1	1.23e-04	195	110	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VPS13C KIF21A HEATR5A ADGRV1 ICAM5	1.29e-04	197	110	5	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1C KRT14 OR2M3 NAV3 DKK3	1.29e-04	197	110	5	44673c38384453207871d3fd8e8ba9093cc06bc5
ToppCell	Control-PLT_4\|Control / Disease Group and Platelet Clusters	ARHGAP32 SETX THAP4 XIRP2 VPS13B	1.32e-04	198	110	5	387fd3037fd52e4d4c42de0588767e58af228b59
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK1 ARHGAP32 ADGRV1 KDM6A VPS13B	1.32e-04	198	110	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB2 MFAP2 ADAMTS16 DKK3 VCAM1	1.35e-04	199	110	5	b9338b739162cd8e5661c9a4dcb41a31219b5723
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADGRB2 MFAP2 ADAMTS16 DKK3 VCAM1	1.35e-04	199	110	5	c972d3036151403f26fa9d6271520639c281ab84
ToppCell	Hematolymphoid-Endothelial-NOSTRIN\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK1 CACNA1C MPDZ ABCB1 IQSEC1	1.38e-04	200	110	5	032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCell	Hematolymphoid-Endothelial-NOSTRIN---\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK1 CACNA1C MPDZ ABCB1 IQSEC1	1.38e-04	200	110	5	68fce28690246895fd33354b30960ebcc31aa4cc
ToppCell	Hematolymphoid-Endothelial-NOSTRIN-\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK1 CACNA1C MPDZ ABCB1 IQSEC1	1.38e-04	200	110	5	376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCell	Hematolymphoid-Endothelial-NOSTRIN--\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK1 CACNA1C MPDZ ABCB1 IQSEC1	1.38e-04	200	110	5	7fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCell	Neuronal-Excitatory\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ARHGAP32 TESPA1 NAV3 ATP2B1 ATP2B4	1.38e-04	200	110	5	4409065bc7aa995354c71e0f9d6f3726cf393d6b
ToppCell	Hematolymphoid-Endothelial-NOSTRIN----L2-6\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK1 CACNA1C MPDZ ABCB1 IQSEC1	1.38e-04	200	110	5	878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCell	Hematolymphoid-Endothelial\|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic	DOCK1 CACNA1C MPDZ ABCB1 IQSEC1	1.38e-04	200	110	5	7136936d05ab344a560cf159684c881063b5430d
Computational	Genes in the cancer module 68.	KRT14 KRT16 KRT35	2.72e-04	26	53	3	MODULE_68
Computational	Keratin.	KRT14 KRT16 KRT35	2.72e-04	26	53	3	MODULE_298
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	3.68e-05	3	104	2	DOID:0111590 (implicated_via_orthology)
Disease	Timothy syndrome (implicated_via_orthology)	CACNA1C CACNA1S	7.35e-05	4	104	2	DOID:0060173 (implicated_via_orthology)
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B1 ATP2B4	1.83e-04	6	104	2	DOID:0050429 (implicated_via_orthology)
Disease	Cataract	ERCC6 TKFC ATP2B1	3.03e-04	37	104	3	C0086543
Disease	Hypercholesterolemia	HMGCR ABCG5 VCAM1	3.54e-04	39	104	3	C0020443
Disease	Anemia, Sickle Cell	CACNA1C VCAM1	5.44e-04	10	104	2	C0002895
Disease	abdominal adipose tissue measurement	CACNA1S TLN2 ATP2B4	8.77e-04	53	104	3	EFO_0803316
Disease	sphingomyelin 18:1 measurement	CACNA1C LZTS1	9.36e-04	13	104	2	EFO_0010394
Disease	Neoplasm of lung	ERCC6 SLC22A18	1.09e-03	14	104	2	cv:C0024121
Disease	Lung cancer	ERCC6 SLC22A18	1.09e-03	14	104	2	cv:C0242379
Disease	LUNG CANCER	ERCC6 SLC22A18	1.09e-03	14	104	2	211980
Disease	response to olanzapine	CACNA1C ADGRV1	1.25e-03	15	104	2	GO_0097333
Disease	Blood Platelet Disorders	ARPC1B ABCG5	1.43e-03	16	104	2	C0005818
Disease	Malignant neoplasm of breast	KRT14 ERCC6 ACO2 MCF2L2 PPA1 ZNF546 ABCB1 SLC22A18 PER3 ICAM5 VPS13B	1.44e-03	1074	104	11	C0006142
Disease	Ulcerative Colitis	ABCB1 PTPN2 VCAM1	1.45e-03	63	104	3	C0009324
Disease	non-alcoholic fatty liver disease (biomarker_via_orthology)	HMGCR ABCB1 ABCG5	1.59e-03	65	104	3	DOID:0080208 (biomarker_via_orthology)
Disease	Coronary Arteriosclerosis	ATP2B1 ABCG5 ANKS1A	1.59e-03	65	104	3	C0010054
Disease	Coronary Artery Disease	ATP2B1 ABCG5 ANKS1A	1.59e-03	65	104	3	C1956346
Disease	Age-related macular degeneration	ERCC6 C2	1.81e-03	18	104	2	cv:C0242383
Disease	Hypercholesterolemia, Familial	HMGCR ABCG5	1.81e-03	18	104	2	C0020445
Disease	cerebral microbleeds	LCORL ABCB1	2.02e-03	19	104	2	EFO_0010059
Disease	Mental Depression	CACNA1C GRPR ABCB1 PER3 SLC18A2	2.09e-03	254	104	5	C0011570
Disease	end stage renal disease (implicated_via_orthology)	HMGCR ABCB1	2.24e-03	20	104	2	DOID:783 (implicated_via_orthology)
Disease	retinal vasculature measurement	CACNA1C ACO2 XIRP2 LZTS1 IQSEC1 NAV3 ELP4	2.40e-03	517	104	7	EFO_0010554
Disease	diaphragmatic hernia	PNPT1 ADAMTS16	2.47e-03	21	104	2	EFO_0008561
Disease	axial length measurement	PIGZ ZNF469 ADAMTS16	2.58e-03	77	104	3	EFO_0005318
Disease	diastolic blood pressure, systolic blood pressure	CACNA1C DNAH2 PDLIM5 PNPT1 SEC16A TLN2 MYOCD ATP2B4	2.58e-03	670	104	8	EFO_0006335, EFO_0006336
Disease	Alcoholic Intoxication, Chronic	MPDZ ADH6 SLC22A18 PER3 SLC18A2	2.64e-03	268	104	5	C0001973
Disease	cortical surface area measurement	GLS2 LCORL TUT7 HMGCR ADGRV1 MFAP2 ZNF469 NAV3 TLN2 MCTP2 PID1 ANKS1A	2.77e-03	1345	104	12	EFO_0010736
Disease	dilated cardiomyopathy (implicated_via_orthology)	EXOSC1 PDLIM5 MYOCD	2.87e-03	80	104	3	DOID:12930 (implicated_via_orthology)
Disease	Carcinoma of lung	ERCC6 SLC22A18	2.97e-03	23	104	2	C0684249
Disease	Brugada Syndrome (disorder)	CACNA1C TRPM4	3.23e-03	24	104	2	C1142166
Disease	Pseudoaphakia	ERCC6 ATP2B1	3.23e-03	24	104	2	C0524524
Disease	Lens Opacities	ERCC6 ATP2B1	3.23e-03	24	104	2	C1510497
Disease	squamous cell lung carcinoma, family history of lung cancer	LCORL ETFBKMT ITLN2	3.41e-03	85	104	3	EFO_0000708, EFO_0006953
Disease	Colorectal Carcinoma	ERCC6 MCF2L2 ABCB1 CNPPD1 KCNA10 ABCA5 ICAM5 KDM6A	3.43e-03	702	104	8	C0009402
Disease	response to gemcitabine	DOCK1 CACNA1C	3.50e-03	25	104	2	GO_0036272

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGTGKSTLMNILCGL	ABCA5	516	Q8WWZ7
ATICNMGAEIGATTS	ACO2	281	Q99798
GQSRVLSKGVCTMTA	ADGRB2	986	O60241
STRKSGSTGNICSVM	LINC00479	116	Q96M42
TQLMSDGTSRFTCKG	ADH6	121	P28332
SGGKAKCSQFCTTGM	ARPC1B	336	O15143
QSVSGTTTCTMGQTK	ADGRV1	5431	Q8WXG9
MGSRSESLSNCSIGK	ANKS1A	641	Q92625
NGECSNSSGTGKTSM	ERCC6	1126	Q03468
MGNATAICSDKTGTL	ATP2B1	466	P20020
MGNATAICSDKTGTL	ATP2B4	456	P23634
NSSVALSTCQGLSGM	ADAMTS16	156	Q8TE57
SALGICTSTVGMKCT	CLDN20	91	P56880
MSGFCKAALNTSAGN	RBM48	176	Q5RL73
STACQSSVAGMEGSV	NR2C1	336	P13056
TGDRCTGLSSKMQDT	PTPN2	326	P17706
GQVDKASLCGSMTSN	SPAG9	816	O60271
VGNSGCGKSTTVQLM	ABCB1	426	P08183
KLCGSSDLNASMTSQ	MCTP2	156	Q6DN12
LCSGALSDSGRNSMS	LZTS1	166	Q9Y250
RQFTSSSSMKGSCGI	KRT14	6	P02533
NVGSSNCITLMEASG	HMGCR	771	P04035
SKLTDTICGVGNMSA	C2	456	P06681
SMSQCSSLKKESGNG	IQSEC1	886	Q6DN90
NMTDSGTGSCKNSSK	LCORL	586	Q8N3X6
SKMGNITVDSSSGCL	FAM185A	271	Q8N0U4
MKSCGVSLATAAAAA	KDM6A	1	O15550
TGGIKGCSSREFSSM	MCF2L2	1001	Q86YR7
LGKVSTTGMQFLSGC	PID1	96	Q7Z2X4
LSTAMLSLGSGISQC	PER3	616	P56645
GLSSNNSTLSVAGAM	ICAM5	791	Q9UMF0
DGFRGKMCSSASSTS	KIAA0232	1356	Q92628
CTLSSDLSVGGKNMF	IGLV11-55	41	A0A075B6I3
LSGSKSISMAGCVTQ	OR2M2	86	Q96R28
LSGSKSISMAGCATQ	OR2M3	86	Q8NG83
LSGSKSISMAGCATQ	OR2M5	86	A3KFT3
LSGSKSISMAGCATQ	OR2M7	86	Q8NG81
TTTMTASVGACLALG	OR5B2	131	Q96R09
GDCGSASMKPSQSAS	NAV3	1751	Q8IVL0
TCVGSQLSMSSSKAS	FBXW7-AS1	26	B0L3A2
RQFTSSSSMKGSCGI	KRT16	6	P08779
GKMASQCSCGESTVT	KDM4E	301	B2RXH2
SKKSMSCSLTGSLAL	LCT	326	P09848
SLAGCLMKSSENGAL	EXOSC1	36	Q9Y3B2
TCESGSVMAATLANG	GLS2	356	Q9UI32
MASKCLKAGFSSGSL	KRT35	1	Q92764
KGCTGSLNMTLQRAS	PDLIM5	71	Q96HC4
TSMTTGNKVISFAGC	OR6C4	81	Q8NGE1
GDLTLKTCGSTASMK	ARHGAP32	86	A7KAX9
VCTEESLMSSLNGGS	MYOCD	491	Q8IZQ8
SKIQAGNMLGTACGT	PNCK	161	Q6P2M8
MGSTDSLNKTNGGCS	KCNA10	491	Q16322
SLANVSSCLEGSMGL	CNPPD1	291	Q9BV87
SMCQGSSSGATIKSP	HEATR5A	1531	Q86XA9
QAKLMGSAGNATIST	CACNA1C	61	Q13936
GHSATGKSMQSLGSC	DOCK1	581	Q14185
TSGIETTCASNMLKG	QRSL1	81	Q9H0R6
GMASSLGCLNLGSSL	CACNA1S	1841	Q13698
TGRSTTCMTSLKSTN	GRPR	351	P30550
NRSGMACKTTATTSS	REXO1L1P	251	Q8IX06
IMCILGSSGSGKTTL	ABCG5	81	Q9H222
GAKSCIMNSGASGSR	ADAM9	366	Q13443
TSGCSAAAASSLEML	ITLN2	21	Q8WWU7
NGKGISCMNTTLSES	PPA1	236	Q15181
SCLKGFQMCVSSSSS	C16orf74	6	Q96GX8
CGATAIAAKMSGASR	ETFBKMT	126	Q8IXQ9
MAAVATCGSVAASTG	ELP4	1	Q96EB1
MGCSSSALNKAGDSS	ERICH5	1	Q6P6B1
KRLSGAMCTSCASQT	GPR21	316	Q99679
SRHSTMIVGCTGSGK	DNAH2	2076	Q9P225
HGAVSLTMCKLTSGK	RNASE7	101	Q9H1E1
TKMATRGSNGTICDN	DKK3	196	Q9UBP4
GVMASSGLCQSVAAS	MFAP2	161	P55001
KGSSMKCSSLSSEAI	PBOV1	91	Q9GZY1
ATCGMRKTSLETSNS	TRMT13	371	Q9NUP7
MSGGLVNGSSVTVSC	VCAM1	411	P19320
GAKGSTVNTMQISCL	POLR1A	901	O95602
TSLQTCASLSGKAVM	SIMC1	76	Q8NDZ2
KSSGNCSKGTAMISS	SETX	506	Q7Z333
CSKGTAMISSLSLHS	SETX	511	Q7Z333
SNAGSKSSVMDGAIA	WDR20	441	Q8TBZ3
VLESNGSSSMASACG	PNPT1	476	Q8TCS8
GSSSMASACGGSLAL	PNPT1	481	Q8TCS8
AVSTSDTGTMLGLCA	SLC22A18	356	Q96BI1
VTSGGTESILMACKA	SGPL1	206	O95470
LACGTMSSTCGQLAS	SLC25A25	381	Q6KCM7
QGGADTLSQTMGKSC	XIRP2	1816	A4UGR9
CAVVSSSGQMLGSGL	ST6GALNAC4	76	Q9H4F1
IAKGNSSLGMTVSAN	MPDZ	1011	O75970
QGGELSRCSSMSSLS	SEC16A	2286	O15027
FCGLGLVSTNKSCSM	RNF122	11	Q9H9V4
SEGSTLSSDLMKLCG	KIF21A	1131	Q7Z4S6
ETQGELTSSCGSKTM	ZNF546	41	Q86UE3
LTSSCGSKTMANVSL	ZNF546	46	Q86UE3
TVSKFASICTMGANA	USP12	6	O75317
MNLTCAVGTTGQKSI	WAPL	1166	Q7Z5K2
LGVKCMSTSASALLA	TLNRD1	216	Q9H1K6
ISSGNTMNITISKSC	VPS13C	2381	Q709C8
GLCSSIGSCLSMKSS	ZNF518A	1026	Q6AHZ1
IGSCLSMKSSSENTL	ZNF518A	1031	Q6AHZ1
MQICGSSVASVAAGT	PIGZ	1	Q86VD9
GKGSGCSVALMSHLS	ZNF469	1516	Q96JG9
CSTSLVKCASGTMGS	VPS13B	861	Q7Z7G8
TSKAVGSSMAQLLTC	TLN2	1096	Q9Y4G6
GCSLASSSMTGGTNK	TESPA1	131	A2RU30
KAMGTLGVSLSSCSV	TKFC	186	Q3LXA3
KMCDIGDASRGSLSS	TUT7	1156	Q5VYS8
SSCSSVAGMGMLASV	SLC18A2	196	Q05940
SKCMLKTLSSTGQGN	ZNF468	51	Q5VIY5
TMVAGSQGKAEASAT	THAP4	181	Q8WY91
SLMCSGSSLVASAGL	ULK1	381	O75385
MGSNAVSSALGACLL	TRPM4	581	Q8TD43
ADAAKLTMNGTSSAG	ZFYVE9	841	O95405
TTALIFSSGKMVCTG	TBPL2	246	Q6SJ96