Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptidase activity	ADAMTS19 USP13 MASP1 SCRN3 NAALADL1 RHBDF1 ADAM7 USP37 USP31 BMP1 TLL1 MINDY4 CTSV ZRANB1	1.78e-04	654	138	14	GO:0008233
GeneOntologyMolecularFunction	calcium ion binding	MASP1 LPCAT1 NAALADL1 PLA2G4D SELENON SYT10 ITIH1 MICU1 BMP1 MYOF CADPS TLL1 VCAN TESC MCTP2	2.14e-04	749	138	15	GO:0005509
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH2 DNAH8 DNAH11	2.44e-04	18	138	3	GO:0008569
GeneOntologyCellularComponent	extracellular matrix	GPLD1 ADAMTS19 COL6A6 EMILIN2 VWA1 ITIH1 ITIH3 C17orf58 BMP1 FCGBP VCAN USH2A CTSV	3.59e-04	656	136	13	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	GPLD1 ADAMTS19 COL6A6 EMILIN2 VWA1 ITIH1 ITIH3 C17orf58 BMP1 FCGBP VCAN USH2A CTSV	3.69e-04	658	136	13	GO:0030312
GeneOntologyCellularComponent	Sin3-type complex	SIN3B SIN3A HDAC2	3.79e-04	22	136	3	GO:0070822
GeneOntologyCellularComponent	apolipoprotein B mRNA editing enzyme complex	A1CF RBM47	4.15e-04	5	136	2	GO:0030895
Domain	HnRNP_R/Q_splicing_fac	A1CF RBM46 RBM47	3.74e-06	5	136	3	IPR006535
Domain	DHC_N1	DNAH2 DNAH8 DNAH11	2.06e-05	8	136	3	PF08385
Domain	Dynein_heavy_dom-1	DNAH2 DNAH8 DNAH11	2.06e-05	8	136	3	IPR013594
Domain	HDAC_interact	SIN3B SIN3A	5.26e-05	2	136	2	SM00761
Domain	Sin3_C	SIN3B SIN3A	5.26e-05	2	136	2	IPR031693
Domain	Sin3_corepress	SIN3B SIN3A	5.26e-05	2	136	2	PF08295
Domain	Sin3a_C	SIN3B SIN3A	5.26e-05	2	136	2	PF16879
Domain	HDAC_interact_dom	SIN3B SIN3A	5.26e-05	2	136	2	IPR013194
Domain	VWA	COL6A6 VWA1 ITGAM ITIH1 ITIH3	5.39e-05	56	136	5	PF00092
Domain	Semap_dom	SEMA6B SEMA4C PLXNA4 PLXNB1	7.27e-05	31	136	4	IPR001627
Domain	SEMA	SEMA6B SEMA4C PLXNA4 PLXNB1	7.27e-05	31	136	4	PS51004
Domain	Sema	SEMA6B SEMA4C PLXNA4 PLXNB1	7.27e-05	31	136	4	SM00630
Domain	Sema	SEMA6B SEMA4C PLXNA4 PLXNB1	7.27e-05	31	136	4	PF01403
Domain	Plexin_repeat	SEMA6B SEMA4C PLXNA4 PLXNB1	8.26e-05	32	136	4	IPR002165
Domain	PSI	SEMA6B SEMA4C PLXNA4 PLXNB1	8.26e-05	32	136	4	PF01437
Domain	VWF_A	COL6A6 VWA1 ITGAM ITIH1 ITIH3 SEC24B	8.59e-05	99	136	6	IPR002035
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	IPR013602
Domain	DHC_N2	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	IPR011704
Domain	MT	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	PF12777
Domain	AAA_8	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	PF12780
Domain	AAA_5	DNAH2 DNAH8 DNAH11	1.30e-04	14	136	3	PF07728
Domain	PAH	SIN3B SIN3A	1.57e-04	3	136	2	IPR003822
Domain	-	SIN3B SIN3A	1.57e-04	3	136	2	1.20.1160.11
Domain	PAH	SIN3B SIN3A	1.57e-04	3	136	2	PS51477
Domain	BMP_1/tolloid-like	BMP1 TLL1	1.57e-04	3	136	2	IPR015446
Domain	PAH	SIN3B SIN3A	1.57e-04	3	136	2	PF02671
Domain	DHC_fam	DNAH2 DNAH8 DNAH11	1.61e-04	15	136	3	IPR026983
Domain	Dynein_heavy	DNAH2 DNAH8 DNAH11	1.61e-04	15	136	3	PF03028
Domain	Dynein_heavy_dom	DNAH2 DNAH8 DNAH11	1.61e-04	15	136	3	IPR004273
Domain	-	SEMA6B SEMA4C WDR11 PLXNA4 WDR41 TAF5L WDFY3 PLXNB1 WDR24 BRWD1	1.66e-04	333	136	10	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	SEMA6B SEMA4C WDR11 PLXNA4 WDR41 TAF5L WDFY3 PLXNB1 WDR24 BRWD1	1.74e-04	335	136	10	IPR015943
Domain	-	COL6A6 VWA1 ITIH1 ITIH3 SEC24B	2.05e-04	74	136	5	3.40.50.410
Domain	PSI	SEMA6B SEMA4C PLXNA4 PLXNB1	2.91e-04	44	136	4	IPR016201
Domain	VWFA	COL6A6 VWA1 ITGAM ITIH1 ITIH3	3.31e-04	82	136	5	PS50234
Domain	PSI	SEMA6B SEMA4C PLXNA4 PLXNB1	3.46e-04	46	136	4	SM00423
Domain	VWA	COL6A6 VWA1 ITGAM ITIH1 ITIH3	3.70e-04	84	136	5	SM00327
Domain	ITI_HC_C	ITIH1 ITIH3	7.75e-04	6	136	2	IPR010600
Domain	Peptidase_M12A	BMP1 TLL1	7.75e-04	6	136	2	IPR001506
Domain	Astacin	BMP1 TLL1	7.75e-04	6	136	2	PF01400
Domain	ITI_HC_C	ITIH1 ITIH3	7.75e-04	6	136	2	PF06668
Domain	WD40_repeat_CS	WDR11 WDR41 TAF5L WDFY3 WDR24 BRWD1	1.28e-03	164	136	6	IPR019775
Domain	VIT	ITIH1 ITIH3	1.43e-03	8	136	2	PF08487
Domain	VIT	ITIH1 ITIH3	1.43e-03	8	136	2	SM00609
Domain	Plexin_cytopl	PLXNA4 PLXNB1	1.83e-03	9	136	2	PF08337
Domain	Plexin_cytoplasmic_RasGAP_dom	PLXNA4 PLXNB1	1.83e-03	9	136	2	IPR013548
Domain	Plexin	PLXNA4 PLXNB1	1.83e-03	9	136	2	IPR031148
Domain	VIT	ITIH1 ITIH3	2.28e-03	10	136	2	PS51468
Domain	VIT	ITIH1 ITIH3	2.28e-03	10	136	2	IPR013694
Pubmed	Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.	SIN3B LPCAT1 SIN3A IFIT1 HDAC2	1.29e-07	30	140	5	16449650
Pubmed	Survival motor neuron (SMN) protein interacts with transcription corepressor mSin3A.	SIN3B SIN3A HDAC2	2.55e-07	4	140	3	14749338
Pubmed	The Mad1-Sin3B interaction involves a novel helical fold.	SIN3B SIN3A HDAC2	1.27e-06	6	140	3	11101889
Pubmed	An ERG (ets-related gene)-associated histone methyltransferase interacts with histone deacetylases 1/2 and transcription co-repressors mSin3A/B.	SIN3B SIN3A HDAC2	1.27e-06	6	140	3	12398767
Pubmed	Homo-oligomerisation and nuclear localisation of mouse histone deacetylase 1.	SIN3B SIN3A HDAC2	1.27e-06	6	140	3	11302704
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	SIN3B MASP1 LPCAT1 TRAF5 SETD1B HACD3 MYO10 ICE2 NDUFS2 SEMA4C MICU1 BMP1 UBR5 KMT5B DHODH KDM2A TAF5L ZRANB1 WDR24	1.69e-06	1327	140	19	32694731
Pubmed	Repression by Ikaros and Aiolos is mediated through histone deacetylase complexes.	SIN3B SIN3A HDAC2	2.21e-06	7	140	3	10357820
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH2 DNAH8 DNAH11	2.21e-06	7	140	3	9256245
Pubmed	Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.	DNAH2 DNAH8 DNAH11	2.21e-06	7	140	3	31178125
Pubmed	SAP30, a component of the mSin3 corepressor complex involved in N-CoR-mediated repression by specific transcription factors.	SIN3B SIN3A HDAC2	5.27e-06	9	140	3	9702189
Pubmed	RBP1 recruits the mSIN3-histone deacetylase complex to the pocket of retinoblastoma tumor suppressor family proteins found in limited discrete regions of the nucleus at growth arrest.	SIN3B SIN3A HDAC2	5.27e-06	9	140	3	11283269
Pubmed	Purification and characterization of mSin3A-containing Brg1 and hBrm chromatin remodeling complexes.	POLR2A SIN3A HDAC2	7.50e-06	10	140	3	11238380
Pubmed	Breast cancer metastasis suppressor 1 (BRMS1) forms complexes with retinoblastoma-binding protein 1 (RBP1) and the mSin3 histone deacetylase complex and represses transcription.	SIN3B SIN3A HDAC2	1.03e-05	11	140	3	14581478
Pubmed	A systematic expression analysis implicates Plexin-B2 and its ligand Sema4C in the regulation of the vascular and endocrine system.	ITGAM SEMA4C PLXNB1	1.37e-05	12	140	3	20478304
Pubmed	The chromatin-binding protein Smyd1 restricts adult mammalian heart growth.	A1CF SMYD1	1.61e-05	2	140	2	27663768
Pubmed	Bone morphogenetic protein 1 processes prolactin to a 17-kDa antiangiogenic factor.	BMP1 PRL	1.61e-05	2	140	2	17548836
Pubmed	Skeletal muscle expression of bone morphogenetic protein-1 and tolloid-like-1 extracellular proteases in different fiber types and in response to unloading, food deprivation and differentiation.	BMP1 TLL1	1.61e-05	2	140	2	20658214
Pubmed	Tandem orientation of the inter-alpha-trypsin inhibitor heavy chain H1 and H3 genes.	ITIH1 ITIH3	1.61e-05	2	140	2	7522574
Pubmed	Bone morphogenetic protein-1 and a mammalian tolloid homologue (mTld) are encoded by alternatively spliced transcripts which are differentially expressed in some tissues.	BMP1 TLL1	1.61e-05	2	140	2	7798260
Pubmed	Myocardial Ablation of G Protein-Coupled Receptor Kinase 2 (GRK2) Decreases Ischemia/Reperfusion Injury through an Anti-Intrinsic Apoptotic Pathway.	A1CF GRK2	1.61e-05	2	140	2	23805205
Pubmed	The epigenetic modifier HDAC2 and the checkpoint kinase ATM determine the responses of microsatellite instable colorectal cancer cells to 5-fluorouracil.	ATM HDAC2	1.61e-05	2	140	2	35608750
Pubmed	Human pre-alpha-trypsin inhibitor-precursor heavy chain. cDNA and deduced amino-acid sequence.	ITIH1 ITIH3	1.61e-05	2	140	2	7681778
Pubmed	Characterization of a novel gene product (mammalian tolloid-like) with high sequence similarity to mammalian tolloid/bone morphogenetic protein-1.	BMP1 TLL1	1.61e-05	2	140	2	8661043
Pubmed	Inactivation of bone morphogenetic protein 1 (Bmp1) and tolloid-like 1 (Tll1) in cells expressing type I collagen leads to dental and periodontal defects in mice.	BMP1 TLL1	1.61e-05	2	140	2	28000152
Pubmed	Placental antiangiogenic prolactin fragments are increased in human and rat maternal diabetes.	BMP1 PRL	1.61e-05	2	140	2	24984282
Pubmed	Proteinase bone morphogenetic protein 1, but not tolloid-like 1, plays a dominant role in maintaining periodontal homeostasis.	BMP1 TLL1	1.61e-05	2	140	2	33169406
Pubmed	The mammalian Sin3 proteins are required for muscle development and sarcomere specification.	SIN3B SIN3A	1.61e-05	2	140	2	20956564
Pubmed	Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart.	A1CF SMYD1	1.61e-05	2	140	2	30061404
Pubmed	Differential Complex Formation via Paralogs in the Human Sin3 Protein Interaction Network.	SIN3B SIN3A	1.61e-05	2	140	2	32467258
Pubmed	SIN3A and SIN3B differentially regulate breast cancer metastasis.	SIN3B SIN3A	1.61e-05	2	140	2	27780928
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP13 NAALADL1 USP37 USP31 ZRANB1	1.97e-05	81	140	5	12838346
Pubmed	A molecular dissection of the repression circuitry of Ikaros.	SIN3B SIN3A HDAC2	2.25e-05	14	140	3	12015313
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH2 DNAH8 DNAH11	2.25e-05	14	140	3	9373155
Pubmed	Stable histone deacetylase complexes distinguished by the presence of SANT domain proteins CoREST/kiaa0071 and Mta-L1.	SIN3B SIN3A HDAC2	3.44e-05	16	140	3	11102443
Pubmed	Balance between BDNF and Semaphorins gates the innervation of the mammary gland.	SEMA6B SEMA4C PLXNA4	3.44e-05	16	140	3	30628891
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL6A6 EMILIN2 VWA1 ITIH1 C17orf58 VCAN	3.79e-05	153	140	6	25037231
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	SEMA6B SEMA4C PLXNA4 PLXNB1	3.92e-05	47	140	4	35462405
Pubmed	Sin3a-associated Hdac1 and Hdac2 are essential for hematopoietic stem cell homeostasis and contribute differentially to hematopoiesis.	SIN3A HDAC2	4.81e-05	3	140	2	24763403
Pubmed	Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver.	A1CF RBM47	4.81e-05	3	140	2	30309881
Pubmed	Human inter-alpha-trypsin inhibitor heavy chain H3 gene. Genomic organization, promoter analysis, and gene linkage.	ITIH1 ITIH3	4.81e-05	3	140	2	9756925
Pubmed	Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.	BMP1 TLL1	4.81e-05	3	140	2	18824173
Pubmed	USP37 regulates DNA damage response through stabilizing and deubiquitinating BLM.	USP37 ATM	4.81e-05	3	140	2	34606619
Pubmed	The opposing transcriptional functions of Sin3a and c-Myc are required to maintain tissue homeostasis.	SIN3B SIN3A	4.81e-05	3	140	2	22101514
Pubmed	Migrating monocytes recruited to the spleen play an important role in control of blood stage malaria.	ITGAM LY6H	4.81e-05	3	140	2	19837977
Pubmed	Use of Bmp1/Tll1 doubly homozygous null mice and proteomics to identify and validate in vivo substrates of bone morphogenetic protein 1/tolloid-like metalloproteinases.	BMP1 TLL1	4.81e-05	3	140	2	12808086
Pubmed	BMP1 and TLL1 Are Required for Maintaining Periodontal Homeostasis.	BMP1 TLL1	4.81e-05	3	140	2	28068493
Pubmed	Inherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model.	KMT5B WDFY3	4.81e-05	3	140	2	30564305
Pubmed	Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.	KDM2A KDM7A	4.81e-05	3	140	2	39273051
Pubmed	Precise Spatiotemporal Control of Nodal Na+ Channel Clustering by Bone Morphogenetic Protein-1/Tolloid-like Proteinases.	BMP1 TLL1	4.81e-05	3	140	2	32209430
Pubmed	Sin3 interacts with Foxk1 and regulates myogenic progenitors.	SIN3B SIN3A	4.81e-05	3	140	2	22476904
Pubmed	G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.	A1CF GRK2	4.81e-05	3	140	2	18635825
Pubmed	Comparative assignments of the genes of the inter-alpha-inhibitor family in human and mouse: ITIH4 is close to ITIH1 and ITIH3, on HSA 3 and MMU 14.	ITIH1 ITIH3	4.81e-05	3	140	2	9126497
Pubmed	The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations.	APCDD1 PIEZO2	4.81e-05	3	140	2	21866343
Pubmed	Bone morphogenetic protein-1 processes probiglycan.	BMP1 TLL1	4.81e-05	3	140	2	10896944
Pubmed	A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression.	SIN3B SIN3A	4.81e-05	3	140	2	9139820
Pubmed	Induced ablation of Bmp1 and Tll1 produces osteogenesis imperfecta in mice.	BMP1 TLL1	4.81e-05	3	140	2	24419319
Pubmed	Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.	ITIH1 ITIH3	4.81e-05	3	140	2	2446322
Pubmed	The three heavy-chain precursors for the inter-alpha-inhibitor family in mouse: new members of the multicopper oxidase protein group with differential transcription in liver and brain.	ITIH1 ITIH3	4.81e-05	3	140	2	7534067
Pubmed	Plp1-expresssing perineuronal DRG cells facilitate colonic and somatic chronic mechanical pain involving Piezo2 upregulation in DRG neurons.	POLR2A PIEZO2	4.81e-05	3	140	2	38743566
Pubmed	EDD inhibits ATM-mediated phosphorylation of p53.	UBR5 ATM	4.81e-05	3	140	2	21383020
Pubmed	Histone deacetylase regulation of ATM-mediated DNA damage signaling.	ATM HDAC2	4.81e-05	3	140	2	23939379
Pubmed	Essential Roles of Bone Morphogenetic Protein-1 and Mammalian Tolloid-like 1 in Postnatal Root Dentin Formation.	BMP1 TLL1	4.81e-05	3	140	2	27847137
Pubmed	Inhibition of tumor growth and metastatic spreading by overexpression of inter-alpha-trypsin inhibitor family chains.	ITIH1 ITIH3	4.81e-05	3	140	2	11807786
Pubmed	Association between Interferon-Lambda-3 rs12979860, TLL1 rs17047200 and DDR1 rs4618569 Variant Polymorphisms with the Course and Outcome of SARS-CoV-2 Patients.	DDR1 TLL1	4.81e-05	3	140	2	34071309
Pubmed	Recruitment of the SWI/SNF protein Brg1 by a multiprotein complex effects transcriptional repression in murine erythroid progenitors.	SIN3A HDAC2	4.81e-05	3	140	2	16800816
Pubmed	Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction.	BMP1 TLL1	4.81e-05	3	140	2	19079247
Pubmed	The highly conserved region of the co-repressor Sin3A functionally interacts with the co-repressor Alien.	SIN3B SIN3A	4.81e-05	3	140	2	15173382
Pubmed	The SIN3A histone deacetylase complex is required for a complete transcriptional response to hypoxia.	SIN3A HDAC2	4.81e-05	3	140	2	29059365
Pubmed	UBR5-mediated ubiquitination of ATMIN is required for ionizing radiation-induced ATM signaling and function.	UBR5 ATM	4.81e-05	3	140	2	25092319
Pubmed	Exercise and diabetes have opposite effects on the assembly and O-GlcNAc modification of the mSin3A/HDAC1/2 complex in the heart.	SIN3A HDAC2	4.81e-05	3	140	2	23835259
Pubmed	A DNMT3A2-HDAC2 Complex Is Essential for Genomic Imprinting and Genome Integrity in Mouse Oocytes.	SIN3A HDAC2	4.81e-05	3	140	2	26586441
Pubmed	Structural and functional evidence for a substrate exclusion mechanism in mammalian tolloid like-1 (TLL-1) proteinase.	BMP1 TLL1	4.81e-05	3	140	2	20043912
Pubmed	Analysis of inter-alpha-trypsin inhibitor and a novel trypsin inhibitor, pre-alpha-trypsin inhibitor, from human plasma. Polypeptide chain stoichiometry and assembly by glycan.	ITIH1 ITIH3	4.81e-05	3	140	2	2476436
Pubmed	Interference with Sin3 function induces epigenetic reprogramming and differentiation in breast cancer cells.	SIN3B SIN3A	4.81e-05	3	140	2	20547842
Pubmed	Mammalian tolloid-like 1 binds procollagen C-proteinase enhancer protein 1 and differs from bone morphogenetic protein 1 in the functional roles of homologous protein domains.	BMP1 TLL1	4.81e-05	3	140	2	16507574
Pubmed	Cis interaction between Semaphorin6A and Plexin-A4 modulates the repulsive response to Sema6A.	SEMA6B PLXNA4	4.81e-05	3	140	2	20606624
Pubmed	The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription.	SIN3A HDAC2	4.81e-05	3	140	2	16254079
Pubmed	Comparison of RNA Editing Activity of APOBEC1-A1CF and APOBEC1-RBM47 Complexes Reconstituted in HEK293T Cells.	A1CF RBM47	4.81e-05	3	140	2	30844405
Pubmed	Ataxia telangiectasia mutant protein activates c-Abl tyrosine kinase in response to ionizing radiation.	POLR2A ATM	4.81e-05	3	140	2	9168116
Pubmed	mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad.	SIN3B SIN3A HDAC2	4.98e-05	18	140	3	14559996
Pubmed	Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation.	SIN3B SIN3A HDAC2	4.98e-05	18	140	3	10444591
Pubmed	DDB1 binds histone reader BRWD3 to activate the transcriptional cascade in adipogenesis and promote onset of obesity.	POLR2A WDR11 WDFY3 HDAC2 BRWD1	5.19e-05	99	140	5	34161765
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA6B SEMA4C PLXNA4 PLXNB1	5.86e-05	52	140	4	26633812
Pubmed	Human family with sequence similarity 60 member A (FAM60A) protein: a new subunit of the Sin3 deacetylase complex.	SIN3B SIN3A HDAC2	5.90e-05	19	140	3	22984288
Pubmed	Fam60a defines a variant Sin3a-Hdac complex in embryonic stem cells required for self-renewal.	SIN3B SIN3A HDAC2	5.90e-05	19	140	3	28554894
Pubmed	FOXK2 Elicits Massive Transcription Repression and Suppresses the Hypoxic Response and Breast Cancer Carcinogenesis.	SETD1B SIN3A HDAC2	6.92e-05	20	140	3	27773593
Pubmed	Human Sin3 deacetylase and trithorax-related Set1/Ash2 histone H3-K4 methyltransferase are tethered together selectively by the cell-proliferation factor HCF-1.	SIN3B SIN3A HDAC2	8.05e-05	21	140	3	12670868
Pubmed	GRK2 mediates TCR-induced transactivation of CXCR4 and TCR-CXCR4 complex formation that drives PI3Kγ/PREX1 signaling and T cell cytokine secretion.	GRK2 PREX1	9.60e-05	4	140	2	30018141
Pubmed	Integrin activation by P-Rex1 is required for selectin-mediated slow leukocyte rolling and intravascular crawling.	ITGAM PREX1	9.60e-05	4	140	2	23343834
Pubmed	Biomarkers of ulcerative colitis disease activity CXCL1, CYP2R1, LPCAT1, and NEU4 and their relationship to immune infiltrates.	LPCAT1 CYP2R1	9.60e-05	4	140	2	37495756
Pubmed	Piezo2 regulates colonic mechanical sensitivity in a sex specific manner in mice.	POLR2A PIEZO2	9.60e-05	4	140	2	37061508
Pubmed	The mammalian Tolloid-like 1 gene, Tll1, is necessary for normal septation and positioning of the heart.	BMP1 TLL1	9.60e-05	4	140	2	10331975
Pubmed	The ubiquitously expressed DNA-binding protein late SV40 factor binds Ig switch regions and represses class switching to IgA.	SIN3A HDAC2	9.60e-05	4	140	2	11884454
Pubmed	Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression.	SIN3B SIN3A	9.60e-05	4	140	2	9139821
Pubmed	Neural restrictive silencer factor recruits mSin3 and histone deacetylase complex to repress neuron-specific target genes.	SIN3B SIN3A	9.60e-05	4	140	2	10570134
Pubmed	Mnt transcriptional repressor is functionally regulated during cell cycle progression.	SIN3B SIN3A	9.60e-05	4	140	2	16103876
Pubmed	A role for histone deacetylase activity in HDAC1-mediated transcriptional repression.	SIN3A HDAC2	9.60e-05	4	140	2	9520398
Pubmed	The nuclear protein PH5P of the inter-alpha-inhibitor superfamily: a missing link between poly(ADP-ribose)polymerase and the inter-alpha-inhibitor family and a novel actor of DNA repair?	ITIH1 ITIH3	9.60e-05	4	140	2	10100603
Pubmed	Mxi1-SRalpha: a novel Mxi1 isoform with enhanced transcriptional repression potential.	SIN3B SIN3A	9.60e-05	4	140	2	15467743
Pubmed	BMP1-like proteinases are essential to the structure and wound healing of skin.	BMP1 TLL1	9.60e-05	4	140	2	27363389
Interaction	SAP25 interactions	SIN3B LPCAT1 SIN3A IFIT1 HDAC2	1.41e-06	29	137	5	int:SAP25
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	SIN3B SIN3A HDAC2	1.19e-05	9	96	3	1306
GeneFamily	Histone deacetylases, class I\|EMSY complex\|NuRD complex\|SIN3 histone deacetylase complex	SIN3B SIN3A HDAC2	3.08e-05	12	96	3	1243
GeneFamily	Dyneins, axonemal	DNAH2 DNAH8 DNAH11	9.35e-05	17	96	3	536
GeneFamily	Bone morphogenetic proteins\|Astacins	BMP1 TLL1	4.13e-04	6	96	2	894
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETD1B SMYD1 KMT5B	7.70e-04	34	96	3	487
GeneFamily	Plexins	PLXNA4 PLXNB1	9.80e-04	9	96	2	683
GeneFamily	WD repeat domain containing	WDR11 WDR41 TAF5L WDFY3 WDR24 BRWD1	2.73e-03	262	96	6	362
GeneFamily	Ubiquitin specific peptidases	USP13 USP37 USP31	3.28e-03	56	96	3	366
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA6B SEMA4C	4.98e-03	20	96	2	736
GeneFamily	Apolipoproteins	APOC4 APOL5	5.49e-03	21	96	2	405
Coexpression	NABA_MATRISOME	SEMA6B ADAMTS19 P4HA2 MASP1 COL6A6 ADAM7 EMILIN2 VWA1 ITIH1 ITIH3 C17orf58 SEMA4C IGSF10 BMP1 TLL1 VCAN PLXNA4 USH2A CTSV PRL PLXNB1	8.85e-08	1026	137	21	M5889
Coexpression	NABA_MATRISOME	SEMA6B ADAMTS19 P4HA2 MASP1 COL6A6 ADAM7 EMILIN2 VWA1 ITIH1 ITIH3 C17orf58 SEMA4C IGSF10 BMP1 TLL1 VCAN PLXNA4 CTSV PRL PLXNB1	3.04e-07	1008	137	20	MM17056
Coexpression	NABA_ECM_REGULATORS	ADAMTS19 P4HA2 MASP1 ADAM7 ITIH1 ITIH3 C17orf58 BMP1 TLL1 CTSV	5.28e-07	238	137	10	M3468
Coexpression	NABA_ECM_REGULATORS	ADAMTS19 P4HA2 MASP1 ADAM7 ITIH1 ITIH3 C17orf58 BMP1 TLL1 CTSV	6.15e-07	242	137	10	MM17062
Coexpression	NABA_MATRISOME_ASSOCIATED	SEMA6B ADAMTS19 P4HA2 MASP1 ADAM7 ITIH1 ITIH3 C17orf58 SEMA4C BMP1 TLL1 PLXNA4 CTSV PRL PLXNB1	7.77e-06	738	137	15	MM17058
Coexpression	NABA_MATRISOME_POORLY_METASTATIC_BREAST_CANCER	COL6A6 EMILIN2 VWA1 ITIH3	8.30e-06	25	137	4	M47986
Coexpression	NABA_MATRISOME_ASSOCIATED	SEMA6B ADAMTS19 P4HA2 MASP1 ADAM7 ITIH1 ITIH3 C17orf58 SEMA4C BMP1 TLL1 PLXNA4 CTSV PRL PLXNB1	9.55e-06	751	137	15	M5885
Coexpression	GSE23114_WT_VS_SLE2C1_MOUSE_PERITONEAL_CAVITY_B1A_BCELL_DN	SEMA6B SLC26A1 ITIH3 TBC1D8 IGSF10 TESC IQCK	7.46e-05	194	137	7	M8285
Coexpression	HE_LIM_SUN_FETAL_LUNG_C0_PERICYTE	MASP1 NPR3 TRIB2 BTBD3 MYOF TESC MCTP2	7.71e-05	195	137	7	M45684
Coexpression	GSE22501_PERIPHERAL_BLOOD_VS_CORD_BLOOD_TREG_DN	TRIB2 PON3 GLB1L2 VCAN EFR3B KDM7A WDFY3	8.75e-05	199	137	7	M8367
Coexpression	GSE15330_HSC_VS_PRO_BCELL_DN	LPCAT1 VWA1 NDUFS2 MICU1 BMP1 MYOF TESC	9.03e-05	200	137	7	M7063
Coexpression	GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_UP	SEMA6B ACTR2 ITIH1 ITIH3 GRK2 TBC1D14 CTSV	9.03e-05	200	137	7	M8844
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	CCP110 CDS1 TRIML2 ZGRF1 VPS50 SIN3A URB2 USP37 USP31 UBR5 DROSHA RBM46 MAP3K15 ATM RBM47 DNAH8 WNK3 BRWD1	5.30e-06	822	136	18	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	Myeloid Cells, GN.Bl, CD11b+ Ly6-G+, Blood, avg-3	ABCA13 EMILIN2 ITGAM SELENON IFIT1 TBC1D8 KDM7A MAP3K15 WDFY3 RBM47 MCTP2	6.69e-05	409	136	11	GSM854306_500
CoexpressionAtlas	kidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000	GPM6A CDS1 NPR3 A1CF APCDD1 ICE2 GBE1 RANBP6 ATP8B1 GLB1L2 PTER MYOF PIEZO2 VCAN RBM47 MCTP2	6.71e-05	814	136	16	gudmap_kidney_e15.5_Podocyte_MafB_1000
CoexpressionAtlas	Myeloid Cells, GN.UrAc.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3	SEMA6B EMILIN2 ITGAM SELENON IFIT1 UNC119 TBC1D14 MAP3K15 WDFY3 RBM47 MCTP2	6.84e-05	410	136	11	GSM854312_500
CoexpressionAtlas	DevelopingGonad_e12.5_testes_emap-29069_k-means-cluster#5_top-relative-expression-ranked_1000	DDR1 SIN3B TRIB2 MYO10 TESC MMD2 MMD2	7.23e-05	158	136	7	gudmap_developingGonad_e12.5_testes_k5_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	CCP110 CDS1 TRIML2 ZGRF1 ICE2 VPS50 URB2 USP37 USP31 CYP2R1 RBM46 MAP3K15 ATM DNAH8 WNK3 BRWD1	7.31e-05	820	136	16	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	Myeloid Cells, GN.BM, CD11b+ Ly6-G+, Bone marrow, avg-4	ABCA13 EMILIN2 GBE1 ITGAM SELENON TBC1D8 KDM7A MAP3K15 WDFY3 RBM47 MCTP2	7.62e-05	415	136	11	GSM605846_500
CoexpressionAtlas	Myeloid Cells, GN.Arth.BM, CD11b+ Ly6-G+, Bone marrow, avg-3	ABCA13 EMILIN2 GBE1 ITGAM SELENON TBC1D8 UNC119 KDM7A MAP3K15 WDFY3 RBM47	8.47e-05	420	136	11	GSM854303_500
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#2_top-relative-expression-ranked_500	SIN3B MASP1 TSPAN32 CADPS KDM7A TESC MMD2	1.06e-04	168	136	7	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k2_500
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000	GPM6A MASP1 TRIB2 MYO10 CNTN6 IGSF10 UNC119 MYOF CADPS VCAN RBM46 KDM7A TESC MMD2 WNK3	1.23e-04	768	136	15	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	GPM6A ADAMTS19 MASP1 TRIB2 ZGRF1 PON3 CNTN6 IGSF10 MYOF PIEZO2 VCAN PLXNA4 TESC MCTP2 WNK3	1.40e-04	777	136	15	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ testes_emap-6710_k-means-cluster#2_top-relative-expression-ranked_1000	DDR1 SIN3B TRIB2 MYO10 TESC MMD2 MMD2	1.69e-04	181	136	7	gudmap_developingGonad_e14.5_ testes_1000_k2
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500	CCP110 CDS1 TRIML2 ZGRF1 CYP2R1 RBM46 MAP3K15 ATM DNAH8 WNK3	1.92e-04	385	136	10	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlas	DevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_200	APCDD1 CNTN6 CADPS VCAN MCTP2	2.30e-04	86	136	5	gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k1
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000	MASP1 UNC119 CADPS KDM7A TESC MMD2 WNK3	2.35e-04	191	136	7	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
CoexpressionAtlas	dev gonad_e13.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000	DDR1 SIN3B MASP1 ERP44 TSPAN32 TBC1D8 UNC119 CADPS KDM7A TESC MMD2	2.43e-04	474	136	11	gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_k4_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_1000	TRMT9B P4HA2 NPR3 TRAF5 RANBP6 GLB1L2 USP37 CNTN6 MSRB3 USP31 TLL1 VCAN PLXNA4 RBM46 BRWD1	3.11e-04	837	136	15	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000
CoexpressionAtlas	kidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_500	GPM6A CDS1 NPR3 A1CF GLB1L2 PTER MYOF PIEZO2 VCAN RBM47	3.29e-04	412	136	10	gudmap_kidney_e15.5_Podocyte_MafB_500
CoexpressionAtlas	DevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_100	TESC MMD2 MMD2	3.62e-04	22	136	3	gudmap_developingGonad_e12.5_epididymis_k3_100
CoexpressionAtlas	dev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#3_top-relative-expression-ranked_500	SIN3B MASP1 TSPAN32 CADPS TESC MMD2	3.73e-04	147	136	6	gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k3_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_top-relative-expression-ranked_500	TRMT9B P4HA2 NPR3 TRAF5 RANBP6 GLB1L2 CNTN6 MSRB3 RBM46 BRWD1	3.83e-04	420	136	10	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#2_top-relative-expression-ranked_500	GPM6A ATP8B1 C17orf58 MYOF RBM47	3.84e-04	96	136	5	gudmap_developingLowerUrinaryTract_P1_ureter_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_top-relative-expression-ranked_500	NPR3 RANBP6 ATP8B1 PTER CNTN6 MSRB3 TLL1 VCAN RBM46 BRWD1	3.97e-04	422	136	10	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_500
ToppCell	Healthy_Control-Myeloid-Mast\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	TRIB2 MYO10 NDFIP2 SYT10 PIEZO2 CADPS P2RY10 MCTP2	8.61e-08	175	140	8	ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell	Healthy_Control-Myeloid-Mast-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	TRIB2 MYO10 NDFIP2 SYT10 PIEZO2 CADPS P2RY10 MCTP2	8.61e-08	175	140	8	eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 GBE1 SYT10 CNTN6 TLL1 TESC MCTP2	8.99e-08	176	140	8	de746cdf2c777eec88cb03863e128e97ad6e8fb0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_THTPA\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 GBE1 SYT10 CNTN6 TLL1 TESC MCTP2	9.81e-08	178	140	8	e4e11e4940c911c17806200c25096928153c684d
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 VWA1 PIEZO2 VCAN KIAA1755 PREX1 PLXNB1	1.43e-07	187	140	8	97e520705491c8f52a32025311a9fa7b9176979a
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic\|GI_large-bowel / Manually curated celltypes from each tissue	SEMA6B EMILIN2 ITGAM MYOF FCGBP VCAN WDFY3 RBM47	1.49e-07	188	140	8	d0045fdda757d191dabc7853f6a6e99c0e97d93d
ToppCell	10x5'-GI_large-bowel-Myeloid_Monocytic-Classical_monocytes\|GI_large-bowel / Manually curated celltypes from each tissue	SEMA6B EMILIN2 ITGAM MYOF FCGBP VCAN WDFY3 RBM47	1.49e-07	188	140	8	0bcf04aa47738f43c1a87dae5dc487738ee86f8c
ToppCell	Neuronal-Excitatory-eH(THEMIS)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MYO10 SMYD1 GBE1 SYT10 CNTN6 CADPS TESC MCTP2	2.40e-07	200	140	8	651ee624ab62720546cf71c2191996b5be3ce846
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EMILIN2 ITGAM DENND1A TBC1D8 VCAN TBC1D14 RBM47 PREX1	2.40e-07	200	140	8	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 CDS1 NPR3 BTBD3 SEMA4C TBC1D8 MCTP2	1.24e-06	172	140	7	30916a902c151907745756d14327e24adc34afef
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 ATP8B1 SYT10 CNTN6 TESC MCTP2	1.61e-06	179	140	7	820289f14ecf165758529c236bb220bb1a744f02
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_GPR21\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 ATP8B1 SYT10 CNTN6 TESC MCTP2	1.61e-06	179	140	7	e5f781d35449628a7f356d71e26231dd63482eec
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 GBE1 ATP8B1 SYT10 TESC MCTP2	1.74e-06	181	140	7	b9fe3833a6a56b9fbe5c257393fdbea5bf8ac4a3
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 GBE1 ATP8B1 SLC26A1 ITIH1 BMP1 MMD2	1.80e-06	182	140	7	770ce9f3f4538d0181a0181543841bc964c68274
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 GBE1 ATP8B1 SLC26A1 ITIH1 BMP1 MMD2	1.80e-06	182	140	7	77ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCell	facs-Liver-Hepatocytes-24m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 GBE1 ATP8B1 SLC26A1 ITIH1 BMP1 MMD2	1.80e-06	182	140	7	4921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCell	facs-Liver-Hepatocytes-24m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 GBE1 ATP8B1 SLC26A1 ITIH1 BMP1 RNF103	1.87e-06	183	140	7	d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 VWA1 PIEZO2 VCAN KIAA1755 PREX1	2.01e-06	185	140	7	b5277190866d9eb5b85eceaa5ba116ea6e6f286b
ToppCell	Fetal_29-31_weeks-Immune-monocyte-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EMILIN2 ITGAM GRK2 VCAN TBC1D14 RBM47 PREX1	2.40e-06	190	140	7	ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A6 EMILIN2 ATP8B1 SELENON IGSF10 BMP1 VCAN	2.57e-06	192	140	7	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	15-Trachea-Epithelial-Intermediate_ciliated\|Trachea / Age, Tissue, Lineage and Cell class	CCP110 CDS1 CFAP300 ABCA13 DNAH2 MINDY4 DNAH11	2.57e-06	192	140	7	9cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SEMA6B EMILIN2 ITGAM DENND1A VCAN RBM47 PREX1	2.85e-06	195	140	7	81a28289eda1a8a1a31b7357106f64ac5000e172
ToppCell	Adult-Immune-monocyte\|Adult / Lineage, Cell type, age group and donor	EMILIN2 ITGAM DENND1A TBC1D8 GRK2 VCAN PREX1	2.95e-06	196	140	7	3ef193c5180de3137daf886492e74fc574bc9767
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EMILIN2 ITGAM DENND1A VCAN KDM7A RBM47 PREX1	2.95e-06	196	140	7	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	EMILIN2 ITGAM DENND1A VCAN TBC1D14 RBM47 PREX1	3.05e-06	197	140	7	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	EMILIN2 ITGAM DENND1A GRK2 VCAN RBM47 PREX1	3.15e-06	198	140	7	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A6 GBE1 IGSF10 MYOF VCAN PLXNA4 KIAA1755	3.26e-06	199	140	7	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10---L5-6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SMYD1 GBE1 SYT10 CNTN6 CADPS TESC MCTP2	3.37e-06	200	140	7	67ba7e5703842e38fa3508ac644461489043626f
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10--\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SMYD1 GBE1 SYT10 CNTN6 CADPS TESC MCTP2	3.37e-06	200	140	7	f545ae8486bd72159247e055f0bb2796c254af61
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SMYD1 GBE1 SYT10 CNTN6 CADPS TESC MCTP2	3.37e-06	200	140	7	8acccefa60031541277fe6c1a7f58f7450961836
ToppCell	Bronchial-NucSeq-Immune_Myeloid-Monocytic-Monocyte_CD14\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EMILIN2 ITGAM DENND1A VCAN TBC1D14 RBM47 PREX1	3.37e-06	200	140	7	5432bdf495431cd26f6e4cd585100f3652588913
ToppCell	Neuronal-Excitatory-eH(THEMIS)-FGF10-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SMYD1 GBE1 SYT10 CNTN6 CADPS TESC MCTP2	3.37e-06	200	140	7	0248fe1eac23704687a2f11c6a3775bceae7a2b1
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature\|E16.5-samps / Age Group, Lineage, Cell class and subclass	GPM6A COL6A6 ITIH3 SEMA4C UNC119 KLHL25	3.39e-06	129	140	6	5e4783cc63afdeaebdfaecb72f95f3efc8d3c4a3
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 SLC2A7 EMILIN2 GBE1 ANO7	6.11e-06	82	140	5	42017b8ace6f142a8358213c95a2632226c3a867
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A USP13 LPCAT1 GLB1L2 P2RY10 LY6H	8.70e-06	152	140	6	d5ba87b5d34e52cef8475befafea962d70fa8a1d
ToppCell	droplet-Liver-LIVER_HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPM6A USP13 LPCAT1 GLB1L2 P2RY10 LY6H	8.70e-06	152	140	6	d88d68a788a3256671ebbc06e104833f1f58f07d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 EMILIN2 RXFP3 CNTN6 BTBD3 IL1RAPL2	1.17e-05	160	140	6	0bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GABRG1 A1CF ABCA13 ADAM7 CNTN6 USH2A	1.25e-05	162	140	6	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	NPR3 TRIB2 VWA1 MSRB3 LY6H PRL	1.49e-05	167	140	6	cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS-Exc_L5-6_THEMIS_IL7R\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 ATP8B1 SYT10 TESC MCTP2	1.59e-05	169	140	6	8b3cc89e42957f18bfb30b8bba8df9ad997bf547
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 POLR2A CNTN6 PLXNA4 USH2A DNAH11	1.59e-05	169	140	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Spleen-nan-18m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 BTBD3 SEMA4C MSRB3 TBC1D8 MCTP2	1.70e-05	171	140	6	4e856441063e9825b6f87a1d3dd19c77dae4662c
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage_dendritic_cell_progenitor\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDR1 CDS1 BTBD3 SEMA4C TBC1D8 MCTP2	1.94e-05	175	140	6	21bc0e59a9509d38751ce6aad2325f341bc70eff
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GPM6A NPR3 SELENON TLL1 TBC1D14 ANO7	2.07e-05	177	140	6	1921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SMYD1 GBE1 PTER CNTN6 TESC MCTP2	2.13e-05	178	140	6	b169aa5eaa51730daaec69c6bc58126be1592a50
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_IT_L5/L6_Car3_THEMIS\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO10 SMYD1 SYT10 CNTN6 TESC MCTP2	2.27e-05	180	140	6	7a9aa96fb8035020640cc7d3df0c41c730516c6f
ToppCell	TCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Adenocarcinoma_Mixed_Subtype\|TCGA-Lung / Sample_Type by Project: Shred V9	LPCAT1 PON3 GLB1L2 PTER TESC RBM47	2.34e-05	181	140	6	c783c2ecca7ab8e07646fa92dc7d436d24939d03
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 MYO10 VCAN MMD2 DNAH11	2.42e-05	182	140	6	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SMYD1 GBE1 PTER SYT10 CNTN6 TESC	2.42e-05	182	140	6	205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 MYO10 VCAN MMD2 DNAH11	2.42e-05	182	140	6	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 VWA1 PIEZO2 VCAN KIAA1755 PREX1	2.57e-05	184	140	6	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPLD1 GPM6A SYT10 SLC26A1 ITIH3 MMD2	2.57e-05	184	140	6	f6148e9591e8845cc62668e49fd52755257cdc7e
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SEMA6B GRK2 VCAN KDM7A USH2A DNAH8	2.73e-05	186	140	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	moderate-Lymphoid-B_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	GPM6A TRAF5 P2RY10 TESC ATM DNAH8	2.73e-05	186	140	6	fd2c4c3e8929ca5d64f6c5064e5f3d3d6ba07b5f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NOL4 P4HA2 NPR3 A1CF PTER KIAA1755	2.73e-05	186	140	6	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 TLL1 VCAN MMD2 DNAH11	2.81e-05	187	140	6	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 TLL1 VCAN MMD2 DNAH11	2.81e-05	187	140	6	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	facs-Lung-EPCAM-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDS1 LPCAT1 ADAM7 PON3 RBM47 PLXNB1	2.90e-05	188	140	6	b1049003ca79c340bb8c78da66bdc0956e1aebc2
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 MYO10 KIAA1755 MMD2 PREX1 PLXNB1	2.90e-05	188	140	6	505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell	facs-Lung-EPCAM-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDS1 LPCAT1 ADAM7 PON3 RBM47 PLXNB1	2.90e-05	188	140	6	3dd571bd8e7358b4346dea71f6bf9602dabf583c
ToppCell	NS-moderate-d_07-13-Lymphoid-B_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	GPM6A TRAF5 P2RY10 TESC ATM DNAH8	2.90e-05	188	140	6	e9ed34cfea1d93eaa8e63d5b5dbb64f1520d9c4c
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTS19 MYO10 MYOF UBR5 VCAN MCTP2	2.90e-05	188	140	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	COPD-Myeloid-cMonocyte\|COPD / Disease state, Lineage and Cell class	SEMA6B EMILIN2 VCAN TBC1D14 RBM47 MCTP2	2.99e-05	189	140	6	d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EMILIN2 ITGAM DENND1A FCGBP TBC1D14 RBM47	2.99e-05	189	140	6	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	APCDD1 MYO10 KIAA1755 MMD2 PREX1 PLXNB1	3.08e-05	190	140	6	2de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 PIEZO2 KIAA1755 PREX1 PLXNB1	3.08e-05	190	140	6	ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-fibroblast\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EMILIN2 SELENON IGSF10 BMP1 VCAN TESC	3.17e-05	191	140	6	9214655dca96d766737c9f30b624d7fe7050342e
ToppCell	Adult-Immune-monocyte-D175\|Adult / Lineage, Cell type, age group and donor	EMILIN2 ITGAM DENND1A GRK2 TBC1D14 PREX1	3.17e-05	191	140	6	cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DDR1 APCDD1 PIEZO2 KIAA1755 PREX1 PLXNB1	3.17e-05	191	140	6	2b056cbe2e82e056e1f798974999378460eb1d16
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	GPM6A NPR3 DENND1A TLL1 VCAN PLXNA4	3.26e-05	192	140	6	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NOL4 ATP8B1 GLB1L2 BMP1 CADPS USH2A	3.26e-05	192	140	6	5b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6A PLA2G4D CNTN6 TLL1 LY6H PRL	3.26e-05	192	140	6	2f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MASP1 NPR3 TRIB2 ATP8B1 TESC MCTP2	3.26e-05	192	140	6	5000440dc1ed17e7474d340921bdff945646f27e
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NOL4 CDS1 CNTN6 IL1RAPL2 TLL1 RBM47	3.36e-05	193	140	6	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TRMT9B ABCA13 DNAH2 TBC1D8 IGSF10 DNAH11	3.36e-05	193	140	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	EMILIN2 ITGAM DENND1A TBC1D14 RBM47 PREX1	3.36e-05	193	140	6	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SEMA6B EMILIN2 ITGAM MYOF VCAN RBM47	3.36e-05	193	140	6	00c9c2945d2bdaa128e054cf3c59df86a279b659
ToppCell	healthy_donor-Myeloid-Monocytic-CD16+_Monocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	EMILIN2 TBC1D8 UNC119 MYOF WDR11 TESC	3.46e-05	194	140	6	ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCell	moderate-Epithelial-FOXN4+\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CCP110 USP13 HACD3 ABCA13 SYT10 MINDY4	3.46e-05	194	140	6	5dffa578149104dda33774361e9e77b227b5f1ce
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A6 IGSF10 MYOF PIEZO2 PLXNA4 KIAA1755	3.46e-05	194	140	6	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	COVID-19-Myeloid-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	EMILIN2 ITGAM DENND1A VCAN RBM47 PREX1	3.66e-05	196	140	6	04d710267658ea5601ae2cfb4ed5acb8a29bd8a1
ToppCell	COVID-19-Myeloid-Transitioning_MDM\|COVID-19 / group, cell type (main and fine annotations)	EMILIN2 DENND1A TBC1D8 TBC1D14 RBM47 PREX1	3.66e-05	196	140	6	4929cfed1f150c1fde4d79cb49895c2ea467a18f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	EMILIN2 ITGAM VCAN TBC1D14 RBM47 PREX1	3.76e-05	197	140	6	8af4a1e35ce9fb4ea3d26ab619599efb7eac43a5
ToppCell	Fetal_29-31_weeks-Immune-monocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EMILIN2 ITGAM VCAN TBC1D14 RBM47 PREX1	3.76e-05	197	140	6	48a8169a4d33c6a68d66bcd936861c75cb4b60ef
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	EMILIN2 ITGAM DENND1A VCAN RBM47 PREX1	3.76e-05	197	140	6	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	COVID-19_Severe-Classical_Monocyte\|World / disease group, cell group and cell class	EMILIN2 ITGAM IFIT1 VCAN WDFY3 RBM47	3.76e-05	197	140	6	344801997b89bd81d8d5c3c872934de523233a8d
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ITGAM ACTR2 VCAN KDM7A TESC RBM47	3.87e-05	198	140	6	c7c5865395992131d0766a03c9c63bad9196b02f
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SEMA6B EMILIN2 ITGAM MYOF VCAN RBM47	3.87e-05	198	140	6	94e2567f057b2c455a9656b121321a28e7cb1d2b
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6A USP13 SLC2A7 MSRB3 PIEZO2 TLL1	3.87e-05	198	140	6	5d42f4fda2081ea3e9f62a00e7eea702e0d0be7d
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic-Classical_monocytes\|lymph-node_spleen / Manually curated celltypes from each tissue	ATP6V1A EMILIN2 ITGAM VCAN WDFY3 RBM47	3.87e-05	198	140	6	187a04d498f0b355cb11c81172721698818082d6
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPM6A USP13 SLC2A7 MSRB3 PIEZO2 TLL1	3.87e-05	198	140	6	99d6a64f3410dae3019161feef20a8f06081a24b
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Monocytic\|lymph-node_spleen / Manually curated celltypes from each tissue	ATP6V1A EMILIN2 ITGAM VCAN WDFY3 RBM47	3.87e-05	198	140	6	065c8a9655d19f93dfdb453c78bbfe7d857caf3e
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPM6A SLC2A7 MSRB3 PIEZO2 TLL1 DHODH	3.98e-05	199	140	6	1587d24b19f5bb64a3b6cc1df87c7c472cf41672
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_lymphatic-Endothelia_Lymphatic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPM6A SLC2A7 MSRB3 PIEZO2 TLL1 DHODH	3.98e-05	199	140	6	a9c2041e54899cb8ccc026758647f3ae3ca457dd
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A6 MYO10 IGSF10 MYOF VCAN PLXNA4	3.98e-05	199	140	6	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Transverse-Macrophage-LYVE1_Macrophage\|Macrophage / Region, Cell class and subclass	RHBDF1 ZGRF1 GBE1 MYOF CYP2R1 TBC1D14	3.98e-05	199	140	6	fd75dccb37d96448edf72b7d042b06833d4ead24
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A6 IGSF10 MYOF VCAN PLXNA4 MINDY4	4.10e-05	200	140	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Neuronal-Excitatory-eH(THEMIS)-DCSTAMP-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	SMYD1 GBE1 SYT10 CNTN6 CADPS TLL1	4.10e-05	200	140	6	1755f7ffe59581f429160aec32669e74d69f5345
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DDR1 CDS1 ABCA13 NDFIP2 MYOF RBM47	4.10e-05	200	140	6	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW19-Neuronal-Neurons\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	TRMT9B GPM6A VCAN PLXNA4 LY6H HDAC2	4.10e-05	200	140	6	b9538eb33ac86384e7e289a5a82fac4d56a7b9c2
Disease	developmental disorder of mental health (implicated_via_orthology)	SIN3B SIN3A CAPZA3 PLXNB1	8.01e-05	49	137	4	DOID:0060037 (implicated_via_orthology)
Disease	cortical surface area measurement, neuroimaging measurement	ADAMTS19 DENND1A C17orf58 MSRB3 VCAN KIAA1755 DNAH11	9.59e-05	227	137	7	EFO_0004346, EFO_0010736
Disease	lifestyle measurement, alcohol consumption measurement	MASP1 RANBP6 TSPAN32 DENND1A PIEZO2	2.04e-04	115	137	5	EFO_0007878, EFO_0010724
Disease	Schizophrenia	GPM6A DDR1 ABCA13 ITGAM ACTR2 ITIH1 ITIH3 WDR11 ATM MCTP2 PRL WNK3 HDAC2	2.49e-04	883	137	13	C0036341
Disease	susceptibility to mononucleosis measurement	GABRG1 DNAH2 MDH2 DNAH8	3.04e-04	69	137	4	EFO_0008403
Disease	Squamous cell carcinoma of lung	DDR1 MAP3K15 WNK3	4.40e-04	32	137	3	C0149782
Disease	AUTISM, SUSCEPTIBILITY TO, 15	POLR2A SIN3A	5.88e-04	8	137	2	C2677504
Disease	age at initiation of corrective lens use	TRIB2 BRWD1	5.88e-04	8	137	2	EFO_0021781
Disease	kynurenine measurement	GBE1 DNAH11 BRWD1	7.92e-04	39	137	3	EFO_0008529
Disease	lifestyle measurement	P4HA2 DENND1A BTBD3 CADPS TESC PREX1	8.26e-04	235	137	6	EFO_0010724
Disease	waist circumference	TRIB2 APCDD1 GBE1 C17orf58 TBC1D32 WDR11 PREX1 IQCK	9.15e-04	429	137	8	EFO_0004342
Disease	Adenocarcinoma of large intestine	GRK2 UBR5 MAP3K15 ATM	1.06e-03	96	137	4	C1319315
Disease	Chagas cardiomyopathy	NPR3 NAALADL1 CAPZA3	1.13e-03	44	137	3	EFO_0005529
Disease	Paranoia	ICE2 DNAH8	1.15e-03	11	137	2	C1456784
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 UBR5	1.15e-03	11	137	2	DOID:3717 (is_implicated_in)
Disease	Lenticulostriate Disorders	MICU1 PRL	1.37e-03	12	137	2	C0750951
Disease	Extrapyramidal Disorders	MICU1 PRL	1.37e-03	12	137	2	C0015371
Disease	Basal Ganglia Diseases	MICU1 PRL	1.37e-03	12	137	2	C0004782
Disease	hippocampal CA1 volume	MSRB3 VCAN ZRANB1	1.45e-03	48	137	3	EFO_0009394
Disease	RAC-beta serine/threonine-protein kinase measurement	GPLD1 APOC4	1.61e-03	13	137	2	EFO_0021989
Disease	preeclampsia, hypertension, pregnancy-induced	NPR3 PREX1	2.46e-03	16	137	2	EFO_0000668, MONDO_0024664
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	UBR5 ATM	2.46e-03	16	137	2	C0334634
Disease	red blood cell density measurement	TRIB2 DNAH2 ATP8B1 TSPAN32 ITIH3 KLHL25 UBR5 KDM2A TAF5L PREX1 ZRANB1	2.74e-03	880	137	11	EFO_0007978
Disease	Benign neoplasm of stomach	UBR5 ATM	2.78e-03	17	137	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	UBR5 ATM	2.78e-03	17	137	2	C0496905
Disease	Carcinoma in situ of stomach	UBR5 ATM	2.78e-03	17	137	2	C0154060
Disease	brain infarction	APCDD1 RBM47	3.12e-03	18	137	2	EFO_0004277
Disease	behavior or behavioral disorder measurement, personality trait	GPM6A BRWD1	3.12e-03	18	137	2	EFO_0004365, EFO_0004782
Disease	serum IgG glycosylation measurement	TRMT9B GPM6A SMYD1 PTGR3 KMT5B CADPS TBC1D14 USH2A	3.15e-03	523	137	8	EFO_0005193
Disease	Adenocarcinoma of prostate	ATM HDAC2	3.85e-03	20	137	2	C0007112
Disease	anxiety	NOL4 DENND1A ITIH1 ITIH3 PLXNA4	3.93e-03	223	137	5	EFO_0005230
Disease	susceptibility to chronic sinus infection measurement	RANBP6 PLXNA4 MAP3K15	3.94e-03	68	137	3	EFO_0008419
Disease	lung cancer	ATP8B1 ZRANB1	4.24e-03	21	137	2	MONDO_0008903
Disease	Stomach Carcinoma	UBR5 ATM	4.24e-03	21	137	2	C0699791
Disease	brain measurement, neuroimaging measurement	ADAMTS19 P4HA2 C17orf58 MSRB3 CADPS VCAN KIAA1755 DNAH11	4.26e-03	550	137	8	EFO_0004346, EFO_0004464

Protein segments in the cluster

Peptide	Gene	Start	Entry
MYSHIAARAEEFAVF	URB2	1431	Q14146
LLSHHNVMGDYRFFD	CAPZA3	71	Q96KX2
HYFTEAMGLTAEARI	C2orf16	271	Q68DN1
MATFVHVYITSFIRG	CDS1	406	Q92903
TYEDRSQLDHMGFHF	VCAN	2656	P13611
FAFVEYESHRAAAMA	A1CF	181	Q9NQ94
ALHGFRVSDYFEYME	TBC1D32	1221	Q96NH3
ISVAMDAGHSSFQFY	CTSV	246	O60911
SETFYSMKGEAFTRH	ADAM7	86	Q9H2U9
HSFSSGYVEMEFEFD	DDR1	261	Q08345
RFLAQLGDYMSFHFE	RTL10	116	Q7L3V2
GSHRDYRVFMSAESA	DNAH11	4011	Q96DT5
SYEGSMEHHFRLSRF	ABCA13	86	Q86UQ4
SSVFHAMFYGELAED	BTBD3	146	Q9Y2F9
STFRGFMQTYYDDHL	APOC4	76	P55056
FDSIMHYARNTFSRG	BMP1	266	P13497
GYAFNHSADFETVRM	ACTR2	201	P61160
SIALYFGIMFDFHSA	ATP8B1	1106	O43520
HGVFSEADMRFYAAE	GRK2	286	P25098
RHGMTSGDYAFFNIE	NPR3	276	P17342
FAFVEYESHRAAAMA	RBM46	186	Q8TBY0
FAFVEYESHRAAAMA	RBM47	196	A0AV96
AMVSYHGADAARRFI	ADAMTS19	336	Q8TE59
VEEMLFHGFSAEHYF	IQCK	86	Q8N0W5
RLFDHGGTVFFSLFM	ANO7	416	Q6IWH7
GMDVADAYVTFVRHS	CADPS	1226	Q9ULU8
ITFADFHRFAEMYPA	LPCAT1	471	Q8NF37
IMASVGTIYVFFFHE	MMD2	141	Q8IY49
LMGVQDSYTDFHIDF	KDM7A	271	Q6ZMT4
QEQFDFHYFSDRMGI	MCTP2	401	Q6DN12
GKESFYDTFHTVADM	HACD3	176	Q9P035
DFLGFYVLDSHRMSA	ITIH1	811	P19827
YNETYFERHATFMDG	SLC2A7	56	Q6PXP3
AFQAELTHFYMAAER	KIAA1755	936	Q5JYT7
YFEMARTAGDTLDVF	GPM6A	61	P51674
MAYAGARFVFSLVDA	MDH2	251	P40926
DGFFFRVHMLALDSS	C17orf58	251	Q2M2W7
HVFIYLRMFATDSGF	KMT5B	181	Q4FZB7
DVDTALSFYHMAGAS	MICU1	376	Q9BPX6
DGMFAYVFHDEFVAS	PLXNA4	211	Q9HCM2
DLTFDGTFEHLYVMT	PLXNB1	456	O43157
LGSEAVHYRISMSFF	OR51B4	16	Q9Y5P0
HRSYDFFVSRFSEMC	EFR3B	136	Q9Y2G0
FHDMVSESCESYFQR	DNAH8	3016	Q96JB1
EDSRNMFALFEYNGH	MYO10	1736	Q9HD67
FQLYRSGLFMTFHVA	OVOS2	286	Q6IE36
KRHFFSDYLMGFINS	LY6H	81	O94772
FEFYERVSGARMHAA	NDUFS2	211	O75306
GFYVDATHSSETRAM	PTER	126	Q96BW5
AEFFTSIGHMTDLIY	P4HA2	21	O15460
SESMAAAHRTRYFFL	NDFIP2	321	Q9NV92
LSMSFFHRLYDEDIV	CFAP300	106	Q9BRQ4
FGYRRLEDFMASHLD	ATM	1201	Q13315
FDGFRFDGVTSMLYH	GBE1	351	Q04446
DMISFSIDRYTFHAN	IGSF10	2181	Q6WRI0
EFYTLHEVTSLMGFF	ICE2	191	Q659A1
LMSVRGCYTDFHVDF	KDM2A	201	Q9Y2K7
ASSRYFEAMFSHGLR	KLHL25	66	Q9H0H3
HTISGDYVIMTIFFD	GABRG1	251	Q8N1C3
FIFVFAALMEYGTLH	GABRG1	341	Q8N1C3
HYVSFDGRRFDFMGT	FCGBP	871	Q9Y6R7
HYTTFDGHRFDFMGT	FCGBP	3661	Q9Y6R7
FGERFTYEDTDFQHM	CYP2R1	196	Q6VVX0
FLGDIHTDATQRMFY	APCDD1	231	Q8J025
GTDIDFTMSYHYRLD	CNTN6	66	Q9UQ52
ALYGIHDIFFVMDAA	CCP110	866	O43303
TGSTDHVIRMYFLGF	BRWD1	341	Q9NSI6
IAIDSFRHMYVFGDF	ERP44	321	Q9BS26
ERFTGFDAHYMAVDV	MASP1	126	P48740
TMQDIHFHYGRFQEF	IFIT1	376	P09914
AFVSHYRSGAMRQFL	DENND1A	341	Q8TEH3
GFTEAVDLYFDHLMS	GLB1L2	166	Q8IW92
HTDFDEMYSTFSGVF	EMILIN2	1031	Q9BXX0
HMFTVGMDVDTRAYF	MT-CO1	291	P00395
EAFYTTDRVMTVSFH	HDAC2	186	Q92769
MFSGDGEYIDFLHSV	DNAH2	1586	Q9P225
TRIGFMTFDSTIHFY	SEC24B	716	O95487
VSSTNFSGEMHFYEL	RNF103	96	O00237
TYTAEALGFSDHMFT	COL6A6	886	A6NMZ7
YFMASEFRDQLSRHG	P2RY10	306	O00398
LGTASAFRFHYMAAL	PLA2G4D	201	Q86XP0
AFRFHYMAALETELS	PLA2G4D	206	Q86XP0
LFYHLGVRESFDMAN	MAP3K15	136	Q6ZN16
SSEMFSEFDKRYTHG	PRL	61	P01236
FFLTAMSVTRYHSVA	RXFP3	171	Q9NSD7
VESFYSRFHGMFLQN	TAF5L	116	O75529
GLSRFTTYEYMLFVH	USH2A	2891	O75445
DHEYIFEGFSMFAHA	DROSHA	596	Q9NRR4
SLGERYDFDSIMHYA	TLL1	286	O43897
GRMVFSYHNSFLIAD	SCRN3	146	Q0VDG4
ELMLFYRQHFGADET	IL1RAPL2	381	Q9NP60
FLGFYVVDSHRMSAQ	ITIH3	791	Q06033
SYLMATGDERFYAEH	DHODH	26	Q02127
DFMRGYFHEEATLCS	RHBDF1	616	Q96CC6
AFEEASFYARRMVDG	SMYD1	366	Q8NB12
QYFRFHADEEMEGTS	PREX1	591	Q8TCU6
DSLREMFTIHAYIAF	SIN3A	981	Q96ST3
TLREMFTIHAYVGFT	SIN3B	871	O75182
EGIGSSYMFRVDHDT	SETD1B	1876	Q9UPS6
LFSLMQYSEEFRIHF	ITGAM	186	P11215
EAITFTDDFSYGMHR	MSRB3	116	Q8IXL7
YVGAREALFAFSMEA	SEMA4C	66	Q9C0C4
FFLRHLAFMDLGYST	OR8K3	61	Q8NH51
FYFHDNVRVAAAESM	RANBP6	721	O60518
EDFFDIIYSMHVETG	NOL4	106	O94818
GSHLSLYFVVMRGEF	TRAF5	456	O00463
VHSDEAGMLSYFLFE	APOL5	66	Q9BWW9
RFLFHMYDSDSDGRI	TESC	116	Q96BS2
AFFRVDHGLMLTYFA	TBC1D14	541	Q9P2M4
DHGLMLTYFAAFEVF	TBC1D14	546	Q9P2M4
AMVLAAESFTSGRHY	TRIML2	291	Q8N7C3
MFLLDSSASVSHYEF	VWA1	36	Q6PCB0
IAFDVIHFMSQLFDY	VPS50	631	Q96JG6
EWGSHVYFFFREIAM	SEMA6B	236	Q9H3T3
ATMDGFHRSFEYIQD	WASHC5	746	Q12768
SDSFYFVDDRLVMHN	UNC119	216	Q13432
HFYVIDGFTMTATRE	WDFY3	2561	Q8IZQ1
RSDIGFLSLFEHYNM	MINDY4	641	Q4G0A6
FFANLIYFLMGTSRH	SLC26A1	106	Q9H2B4
SISLAEMFARSHGYS	SLC26A1	356	Q9H2B4
MVTLTYFGAHFAVIR	TSPAN32	31	Q96QS1
AYVFFERSYGDMHSF	TRIB2	126	Q92519
SYLEMGHDITRLFYS	POLR2A	656	P24928
DHFVEYGRTVCMFRT	TBC1D8	481	O95759
ISDFYYTVMFRIHAE	SELENON	281	Q9NZV5
FLRTMGAIDFHGSYS	GPLD1	141	P80108
DHASMVRSGDYYLFE	PIEZO2	1541	Q9H5I5
ITLSEYFRDMGYHVS	ATP6V1A	331	P38606
RDHYFTNSLLSFFEM	PON3	181	Q15166
FSVYDFDRFSRHDMI	SYT10	316	Q6XYQ8
AIVDMSYARHFLDFQ	PTGR3	11	Q8N4Q0
YLMGFLHAVSRESIF	ARHGAP8	351	P85298
QSDRDRSGYIFFYMH	USP37	936	Q86T82
FFAEAVSGMHFRDTS	ZGRF1	1171	Q86YA3
DVLDSTAFMRYYHVF	TRMT9B	401	Q9P272
EAVGSYDTMDLFRHT	TTC37	906	Q6PGP7
LTEMYYDGFHRSFCD	USP31	366	Q70CQ4
DFFGVLVRDMLHFYA	WDR24	631	Q96S15
CFFSVAETLHSMRYF	WDR11	1136	Q9BZH6
DGSGTYELFAFISHM	USP13	801	Q92995
LIGHSSSVEMFLYFE	WDR41	401	Q9HAD4
SSVEMFLYFEDHGLV	WDR41	406	Q9HAD4
YTRGHFSALVAMEND	ZRANB1	581	Q9UGI0
HDFAFFDPVMYESLR	UBR5	2566	O95071
EVAYEMVKSGFFHES	WNK3	461	Q9BYP7
FTGDDLRVYFMRHFD	NLRP13	386	Q86W25
LRVYFMRHFDDSSEV	NLRP13	391	Q86W25
FVHFLGISSMDIAYT	NAALADL1	516	Q9UQQ1
SFAEGTFTVFAEMYE	MYOF	851	Q9NZM1