Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
Domain-

RGS5 RGS1 RGS4

1.82e-05224431.10.196.10
DomainRGS_subdom1

RGS5 RGS1 RGS4

1.82e-0522443IPR024066
DomainRGS

RGS5 RGS1 RGS4

7.57e-0535443PF00615
DomainRGS

RGS5 RGS1 RGS4

7.57e-0535443SM00315
DomainRGS

RGS5 RGS1 RGS4

8.25e-0536443PS50132
DomainRGS

RGS5 RGS1 RGS4

1.05e-0439443IPR016137
DomainPI3/4_kinase_CS

SMG1 PIK3CG

5.59e-0415442IPR018936
Domain-

SMG1 PIK3CG

6.37e-04164421.10.1070.11
DomainPI3Kc

SMG1 PIK3CG

6.37e-0416442SM00146
DomainPI3/4_kinase_cat_dom

SMG1 PIK3CG

8.10e-0418442IPR000403
DomainPI3_PI4_kinase

SMG1 PIK3CG

8.10e-0418442PF00454
DomainPI3_4_KINASE_3

SMG1 PIK3CG

8.10e-0418442PS50290
DomainPI3_4_KINASE_1

SMG1 PIK3CG

8.10e-0418442PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3CG

8.10e-0418442PS00916
DomainRicin_B_lectin

GALNT12 GALNT7

1.57e-0325442PF00652
DomainRICIN

GALNT12 GALNT7

1.97e-0328442SM00458
DomainRICIN_B_LECTIN

GALNT12 GALNT7

1.97e-0328442PS50231
DomainRicin_B_lectin

GALNT12 GALNT7

2.26e-0330442IPR000772
DomainGlycos_transf_2

GALNT12 GALNT7

2.26e-0330442PF00535
DomainGlyco_trans_2-like

GALNT12 GALNT7

2.26e-0330442IPR001173
Domain-

KLHL6 ATRNL1

5.71e-03484422.120.10.80
DomainCUB

ATRNL1 TLL1

5.95e-0349442PF00431
DomainCUB

ATRNL1 TLL1

6.18e-0350442SM00042
Domain-

ATRNL1 TLL1

6.67e-03524422.60.120.290
DomainCUB

ATRNL1 TLL1

6.93e-0353442PS01180
DomainKelch-typ_b-propeller

KLHL6 ATRNL1

7.44e-0355442IPR015915
DomainCUB_dom

ATRNL1 TLL1

7.97e-0357442IPR000859
DomainARM-type_fold

USP34 SMG1 PIK3CG TTC12

8.18e-03339444IPR016024
Pubmed

Evolution of the regulators of G-protein signaling multigene family in mouse and human.

RGS5 RGS1 RGS4 MUSK

5.33e-075144411829488
Pubmed

Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.

RGS5 RGS1 RGS4

1.27e-061744320627871
Pubmed

Confirming RGS4 as a susceptibility gene for schizophrenia.

RGS5 RGS4

1.56e-06244214755443
Pubmed

A novel regulator of G-protein signaling bearing GAP activity for Galphai and Galphaq in megakaryocytes.

RGS5 RGS1 RGS4

1.80e-061944311342430
Pubmed

Phosphoinositide 3-kinase and Akt occupy central roles in inflammatory responses of Toll-like receptor 2-stimulated neutrophils.

PIK3CG TLR2

4.69e-06344215100319
Pubmed

N-terminal residues control proteasomal degradation of RGS2, RGS4, and RGS5 in human embryonic kidney 293 cells.

RGS5 RGS4

4.69e-06344217220356
Pubmed

Regulator of G Protein Signaling 2 Facilitates Uterine Artery Adaptation During Pregnancy in Mice.

RGS5 RGS4

4.69e-06344231030617
Pubmed

RGS expression in cancer: oncomining the cancer microarray data.

RGS5 RGS1

9.37e-06444223464602
Pubmed

Association of RGS2 and RGS5 variants with schizophrenia symptom severity.

RGS5 RGS4

1.56e-05544218262772
Pubmed

Regulation of protease-activated receptor 1 signaling by the adaptor protein complex 2 and R4 subfamily of regulator of G protein signaling proteins.

RGS5 RGS4

1.56e-05544224297163
Pubmed

RGS proteins: more than just GAPs for heterotrimeric G proteins.

RGS5 RGS4

1.56e-05544210203790
Pubmed

MuSK frizzled-like domain is critical for mammalian neuromuscular junction formation and maintenance.

NEFM MUSK

1.56e-05544225810523
Pubmed

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization.

PIK3CG TLR2

2.34e-05644219574958
Pubmed

Inhibition of G-protein-mediated MAP kinase activation by a new mammalian gene family.

RGS1 RGS4

3.27e-0574428602223
Pubmed

A potent modifier of liver cancer risk on distal mouse chromosome 1: linkage analysis and characterization of congenic lines.

RGS5 RGS4

3.27e-05744215238534
Pubmed

Ca2+/Calmodulin reverses phosphatidylinositol 3,4, 5-trisphosphate-dependent inhibition of regulators of G protein-signaling GTPase-activating protein activity.

RGS1 RGS4

3.27e-05744210747990
Pubmed

Abnormal development of the neuromuscular junction in Nedd4-deficient mice.

NEFM MUSK

3.27e-05744219345204
Pubmed

The muscle protein Dok-7 is essential for neuromuscular synaptogenesis.

NEFM MUSK

3.27e-05744216794080
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

GEMIN4 SNTG1 UBA6 EGLN2 VOPP1 POGZ RGS5

4.04e-0575044711230166
Pubmed

Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning.

NEFM MUSK

4.36e-05844218434415
Pubmed

Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice.

NEFM MUSK

4.36e-05844210655525
Pubmed

Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.

NEFM MUSK

4.36e-05844221441923
Pubmed

APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice.

NEFM MUSK

5.60e-05944223986861
Pubmed

Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction.

NEFM MUSK

5.60e-05944218830404
Pubmed

Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation.

NEFM MUSK

6.99e-051044211395002
Pubmed

Runx2 regulates G protein-coupled signaling pathways to control growth of osteoblast progenitors.

RGS5 RGS4

6.99e-051044218625716
Pubmed

Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor.

NEFM MUSK

8.54e-051144212403715
Pubmed

Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system.

RGS5 RGS4

1.02e-041244224009623
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MR1 USP34 MESD GALNT7 TLL1 GGCX MSLN DMXL1

1.16e-04120144835696571
Pubmed

Acetylcholine negatively regulates development of the neuromuscular junction through distinct cellular mechanisms.

NEFM MUSK

1.21e-041344220498043
Pubmed

Expression of Toll-like receptors in the developing brain.

NEFM TLR2

1.86e-041644222666391
Pubmed

RGS4 and RGS5 are in vivo substrates of the N-end rule pathway.

RGS5 RGS4

1.86e-041644216217033
Pubmed

Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation.

ZSWIM5 RGS4

2.64e-041944228433741
Pubmed

The LIFEdb database in 2006.

SNTG1 UBA6 EGLN2 VOPP1 POGZ RGS5

2.79e-0472044616381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

SNTG1 UBA6 EGLN2 VOPP1 POGZ RGS5

2.83e-0472244615489336
Pubmed

LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction.

NEFM MUSK

3.24e-042144217119023
Pubmed

Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans.

GALNT12 GALNT7

3.56e-042244225107907
Pubmed

Phosphoinositide 3-kinase-dependent inhibition of dendritic cell interleukin-12 production by Giardia lamblia.

PIK3CG TLR2

3.89e-042344219047410
Pubmed

Loss of the disease-associated glycosyltransferase Galnt3 alters Muc10 glycosylation and the composition of the oral microbiome.

GALNT12 GALNT7

4.24e-042444231882545
Pubmed

Galnt11 regulates kidney function by glycosylating the endocytosis receptor megalin to modulate ligand binding.

GALNT12 GALNT7

4.24e-042444231740596
Pubmed

DNA cloning using in vitro site-specific recombination.

SNTG1 UBA6 EGLN2 VOPP1 POGZ RGS5

4.68e-0479444611076863
Pubmed

Galnt1 is required for normal heart valve development and cardiac function.

GALNT12 GALNT7

9.59e-043644225615642
Pubmed

Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development.

NEFM RGS4

1.07e-033844231597102
Pubmed

O-glycosylation modulates integrin and FGF signalling by influencing the secretion of basement membrane components.

GALNT12 GALNT7

1.18e-034044222643896
Cytoband4q13.2

UBA6 UGT2B11

4.10e-04314424q13.2
GeneFamilyRegulators of G-protein signaling

RGS5 RGS1 RGS4

5.94e-0621313720
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT12 GALNT7

5.30e-0420312433
GeneFamilyEndogenous ligands|Minor histocompatibility antigens

GEMIN4 MR1

3.44e-0351312870
ToppCellCOVID-19-kidney-Plasma|COVID-19 / Disease (COVID-19 only), tissue and cell type

KLHL6 VOPP1 MYO1D RGS1 PIK3CG

5.19e-07160445f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

KLHL6 VOPP1 MYO1D RGS1 PIK3CG

7.20e-07171445a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

KLHL6 VOPP1 MYO1D RGS1 PIK3CG

8.07e-07175445fb23858cfce71509cafbe0d9728e678012ff2962
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_dendritic_(11)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD RGS1 PIK3CG MSLN

1.09e-06186445fc6e591089c87a66653c8e552be9c0fe0c82ecd5
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD RGS1 PIK3CG TLR2

1.34e-06194445ef30baa19b7aa97b61dea916fc2e0f5cf49848d6
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 RGS1 PIK3CG

1.97e-05162444ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 RGS1 PIK3CG

1.97e-051624448ed9149ff53b285591354057055d072b203a47c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 RGS1 PIK3CG

1.97e-051624447a05b05a33e1309fb5c0a8171db105ae68491815
ToppCellkidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 RGS1 PIK3CG

1.97e-051624449e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

ITGAD PIK3CG MUSK TLL1

2.21e-05167444d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCelldroplet-Lung-nan-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 UBA6 MYO1D RGS1

2.32e-05169444da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCelldroplet-Lung-nan-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLHL6 UBA6 MYO1D RGS1

2.32e-05169444a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

RAB7B VOPP1 RGS1 PIK3CG

2.43e-051714446a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

RAB7B RGS4 ATRNL1 MSLN

2.54e-05173444e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

RAB7B RGS4 ATRNL1 MSLN

2.54e-0517344474ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellfacs-Trachea-nan-3m-Myeloid-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 PIK3CG TLR2

2.54e-05173444e4eb2ac2cee16bfa8eabc938f8030ee161c972c5
ToppCellfacs-Trachea-nan-3m-Myeloid|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 PIK3CG TLR2

2.54e-05173444371515471459307a3b2adce735263b4aac828956
ToppCellfacs-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 PIK3CG TLR2

2.54e-051734444e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(RGS5+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGS5 EDN2 TLL1 MSLN

2.66e-05175444f5451c29c487b998778e50349b3d774d5e20fd28
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KLHL6 RAB7B VOPP1 PIK3CG

2.78e-05177444c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 RGS1 PIK3CG

2.84e-05178444f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 RGS1 PIK3CG

2.84e-05178444a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_conventional_dendritic_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KLHL6 RAB7B RGS1 PIK3CG

2.90e-051794449fc44637c9a7551fd47b8533e45a9c199e164a95
ToppCellfacs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GEMIN4 POGZ CAPN5 GFM2

2.97e-051804447368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NEFM GALNT12 OCRL RGS4

3.10e-05182444eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KLHL6 VOPP1 MYO1D PIK3CG

3.30e-051854443b77bc49cd3740acc025e162a36282ac09e12198
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RAB7B VOPP1 RGS1

3.37e-05186444305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.52e-051884440d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_dendritic-im_migrating_dendritic_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD RGS1 PIK3CG

3.52e-051884448fc15c8b78fdd1a578e34325011bc5a87a8aab31
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MARS2 RAB7B RGS4 MSLN

3.52e-05188444e82104f71bcdab7392fdb076dc3560255964fd9e
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD RGS1 PIK3CG

3.59e-05189444a438c64a893d43f781ede42e1c7b615b74dc76ef
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_dendritic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD RGS1 PIK3CG

3.67e-051904445e0e4a48159ec05ba1b599752b769a7b4da08588
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.67e-051904447c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.74e-05191444c72e62cf5b45c04ee5e7719db31f917c4f76b1e4
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD PIK3CG TLR2

3.74e-0519144409dfad8e1fcaaf94775134796b99e4e3fbb9bf40
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.82e-0519244486d792682ba51696f503c79625dd20f87bcf651f
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_proliferating_myeloid_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 RGS1 PIK3CG TLR2

3.82e-051924447e7383093efaadceadd4d1f900c2d39cd690102e
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-mesothelial_cell|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RGS5 EDN2 TLL1 MSLN

3.82e-051924442f539653a20006bef814e6b4acd1023d6fdad5c6
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.82e-05192444d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.90e-05193444f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

KLHL6 ITGAD RGS1 PIK3CG

3.90e-051934442684fa361baaa9dc7a18a39ed11c0759e78e4418
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.98e-0519444496f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCellIPF-Epithelial-Mesothelial|Epithelial / Disease state, Lineage and Cell class

RAB7B RGS4 ATRNL1 MSLN

3.98e-05194444d8a26da856a85e3d001d406e992cb18fdd58baef
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KLHL6 RGS1 PIK3CG TLR2

3.98e-05194444846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

3.98e-051944440866ab6792cee274a71991d5c37a37f574ff446e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 RGS1 PIK3CG TLR2

4.06e-0519544491a3c439f10c03c5d51d904f512b6a08040edc76
ToppCellNS-moderate-d_16-33-Epithelial-Secretory|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GALNT12 CAPN5 GALNT7 MSLN

4.14e-0519644470384c1da9baed843f414cfd1403ddd586a2db07
ToppCellPSB-critical-LOC-Epithelial-Secretory|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GALNT12 CAPN5 GALNT7 MSLN

4.30e-05198444e4cbe4032dba0da3fd46817ea9ad86ba9217f747
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 RAB7B VOPP1 PIK3CG

4.30e-05198444fa5c15a656d4132950092919600e270f1fd79abf
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 VOPP1 RGS1 PIK3CG

4.39e-051994441bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 VOPP1 RGS1 PIK3CG

4.39e-0519944458242d78517c05fa367a7c6edac57ef79107453c
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 VOPP1 RGS1 PIK3CG

4.39e-051994442f60682f1b82918a65e8851e99c9e3398845b62f
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KLHL6 VOPP1 RGS1 PIK3CG

4.48e-05200444e1b3fc516887510b18cf688ada0e00b5f5eff684
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RAB7B ITGAD MUSK

1.75e-04110443bede775886b45cce4aa229baead0e800b5be25a8
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MR1 TLR2 TTC12

1.75e-041104433a641dced828ed97a8eea70d0a7b76f33630c9be
ToppCellThalamus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)|Thalamus / BrainAtlas - Mouse McCarroll V32

GALNT12 RGS1 PIK3CG

1.90e-041134439b239bfa00aa2d2e27d13d80fe54ef4f2fea49c0
ToppCellThalamus-Hematopoietic-MICROGLIA|Thalamus / BrainAtlas - Mouse McCarroll V32

GALNT12 RGS1 PIK3CG

1.90e-04113443b82c5dd560a0e309f2b79ca874b006f914baade7
ToppCellThalamus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)--|Thalamus / BrainAtlas - Mouse McCarroll V32

GALNT12 RGS1 PIK3CG

1.90e-04113443f606c2003ce9b17f3c27a7c24ee6bf30f28a2b06
ToppCellThalamus-Hematopoietic-MICROGLIA-MI2(C1qb)|Thalamus / BrainAtlas - Mouse McCarroll V32

GALNT12 RGS1 PIK3CG

1.90e-04113443d5e6f36d2d6afaadfbf60b56c16ed15775139ed4
ToppCelldroplet-Mammary_Gland-nan-3m-Mesenchymal-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MR1 RAB7B RGS5

1.90e-04113443ec4b89e727e1b921b9cb17443774955b95814dd4
ToppCellThalamus-Hematopoietic-MICROGLIA-MI2(C1qb)-MICROGLIA_Microglia.C1qb.Tmem119_(Microglia.C1qb.Tmem119)-|Thalamus / BrainAtlas - Mouse McCarroll V32

GALNT12 RGS1 PIK3CG

1.90e-04113443a339ddee70054612afef3cc9dc156738202af4cd
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

EGLN2 UBTD1 RGS4

2.05e-04116443f32f7eddfe33adb3b5cf7c34667a481a305c5163
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RAB7B UBTD1 CAPN5

2.26e-0412044316c3bd15e3936b68c433c4dd15d655aae64dc960
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P1|Striatum / BrainAtlas - Mouse McCarroll V32

RAB7B CAPN5 ITGAD

3.86e-041444439d6133558728fa148050eb4f0be33756d71310b0
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)|343B / Donor, Lineage, Cell class and subclass (all cells)

GALNT12 MYO1D DMXL1

3.94e-04145443cb534333fba44b241b14fb0d7b74e843f4e7f9f8
ToppCell343B-Epithelial_cells-Epithelial-E_(AT2)-|343B / Donor, Lineage, Cell class and subclass (all cells)

GALNT12 MYO1D DMXL1

3.94e-0414544380684ec249fa445c1b35f94608a4a6824d53f2d9
ToppCellLPS_only-Myeloid-Dendritic_cells-mDC|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAB7B VOPP1 PIK3CG

4.10e-0414744326bd9d89e2e7b841cc18030bb7cebb642b987183
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RAB7B VOPP1 PIK3CG

4.18e-04148443cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBA6 GALNT12 VOPP1

4.52e-0415244387a7116d0064a6051bdf28ce1e48bfc168273e66
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 PIK3CG

4.61e-041534433724dd498b982be693ddff9cea7671863acf3ff8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KLHL6 VOPP1 PIK3CG

4.61e-04153443d810fc5aff28449ce79b4148558b260878a2c696
ToppCellCOVID-19-Heart-CM_5_(RYR2-)|Heart / Disease (COVID-19 only), tissue and cell type

ITGAD ATRNL1 GGCX

4.79e-04155443d7e26696fd9c0a759524f331243db43059b33ed9
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

4.88e-041564436e60e860603a7e8194f437a574ff8e887f6083b8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RGS4 MUSK TLR2

4.97e-04157443a98d06cef80bfe8481b0940abce2b29675e45812
ToppCellE12.5-Hematopoietic|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAB7B PIK3CG TLR2

4.97e-04157443344351c7534440532c6cd4a95782ac90b10d45f3
ToppCellGoblet|World / Class top

GALNT12 GALNT7 MSLN

4.97e-04157443b352aa37d662629db6a9c6def9ee6d7c49a9071c
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-macrophage|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.06e-04158443e5e7b2d609973f1dd4fe7dc62bb69422268ea801
ToppCelldroplet-Bladder-Unstain-18m-Hematologic|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.16e-04159443a80b4637a74bcc6f213d584aba2c727a983eedb3
ToppCelldroplet-Bladder-Unstain-18m-Hematologic-leukocyte|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.16e-0415944389b5e895e95cdd654edd471bde9b6887939b3503
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VOPP1 ITGAD RGS1

5.16e-0415944351bdbacb79227fbee38bb8680c58cb99878df0c7
ToppCelldroplet-Kidney-nan-18m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.25e-04160443d18c4cc99a31481dd0ee8af9299695d5f6857b42
ToppCellE12.5-Hematopoietic-Immune|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAB7B PIK3CG TLR2

5.25e-04160443cd59830a524c14a1f591c5c615b55510e4104e5b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

RIOK2 RGS1 RGS4

5.25e-04160443529034a1101d7772d82f86beb5c6fa9c9dd97067
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OCRL TLL1 GGCX

5.25e-04160443778faada072e3abfa76a9a06fd4885fb63de7902
ToppCelldroplet-Kidney-nan-18m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.25e-04160443a707a4ad9fbedcca227f76b49f1393e88101c2fb
ToppCellE12.5-Hematopoietic-Immune-immune_cell_unspecified|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAB7B PIK3CG TLR2

5.25e-041604435a4a5a50dfdf6af9406e4f685712f7fe390a02f3
ToppCelldroplet-Kidney-nan-18m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.25e-0416044373b604cbdcd9e8f0f317964abc632abee314a557
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.35e-041614433db97af49520dc8cbafb4454d8afd9d588160e89
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.35e-04161443f1d258c81bcf0f3c52bd20aa58faa9a5fd888168
ToppCelldroplet-Mammary_Gland-nan-21m-Myeloid-macrophage|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.35e-04161443787f91f906756ef570c0d02936c3cdfafb3f7454
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KLHL6 PIK3CG TLR2

5.45e-041624432b47fd256490d0c2d9ad5950aa26410aeb6ec995
ToppCellfrontal_cortex-Non-neuronal-macrophage|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RGS1 PIK3CG TLR2

5.54e-04163443b89f586b444f90047c8ce407f53847fd1ee7cca3
ToppCellfrontal_cortex-Non-neuronal-macrophage-Macrophage|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RGS1 PIK3CG TLR2

5.54e-04163443cbe9b4c4b2e42e9f92a57ed66758af93434db5bb
ToppCellPND01-Immune|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL6 RGS1 TLR2

5.54e-0416344398af13bd4257a9da325e1ffe5a254f0f58ca6c4b
ToppCell368C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

RAB7B CAPN5 OCRL

5.54e-04163443299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCellPND01-Immune-Immune_Myeloid|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KLHL6 RGS1 TLR2

5.54e-04163443ca12d01615be371fe215ec673d4ec787381e0ca6
ToppCelldroplet-Kidney-nan-21m-Myeloid-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.64e-04164443d4cdcd61e8c28b3fb912cef8837cc1a49678a729
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid-macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.64e-04164443e19fc6ba049336ab989a3a968bdbefd567971d73
ToppCelldroplet-Kidney-KIDNEY-30m-Myeloid|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB7B RGS1 TLR2

5.64e-04164443d6526551d0b183c3ef027ba3dbfddeac03fd93bb
ToppCellPND01-03-samps-Myeloid-Macrophage|PND01-03-samps / Age Group, Lineage, Cell class and subclass

RAB7B PIK3CG TLR2

5.64e-0416444349733a9d3d95f05056b5b01916060ff20a8de3cf
Diseaseplatelet reactivity measurement, thrombus formation measurement

RGS5 RGS4

4.13e-057422EFO_0004985, EFO_0007615
Diseasephosphatidylcholine 36:4 measurement

UGT2B11 MUSK

2.98e-0418422EFO_0010382
Diseaseresponse to mTOR inhibitor

RGS5 RGS4

5.81e-0425422EFO_0005417
Diseasecardioembolic stroke

USP34 RGS5 RGS4

1.83e-03170423EFO_1001976
Diseasejoint damage measurement

GALNT12 ATRNL1

4.25e-0368422EFO_0005413

Protein segments in the cluster

PeptideGeneStartEntry
DKECVYFCHLDIIWV

EDN2

56

P20800
NEFWCALVEKAYAKL

CAPN5

156

O15484
AGKDDCLLKVWYNVE

DMXL1

186

Q9Y485
WCREKDIPYFEVSAK

RAB7B

141

Q96AH8
NIEFWLACEDYKKTE

RGS1

111

Q08116
KWVEFACVTLKNEVY

KLHL6

366

Q8WZ60
ESCQELREKFWEFYK

MPV17L2

131

Q567V2
VCAEGNEAIWKYLKE

LRRIQ4

486

A6NIV6
EKLWVPDCYFLNSKD

GABRQ

136

Q9UN88
YAWEIKDFLVGQDRC

MESD

166

Q14696
KVWLLKGLCDFVYET

KIAA2026

426

Q5HYC2
IFYKKWELEACVDAA

MSLN

316

Q13421
ISCALYEEFWIKYAK

PRPF39

381

Q86UA1
VAKAVYRCWEEKPSA

ITGAD

631

Q13349
NCKSFKWFMEEIAYD

GALNT7

506

Q86SF2
NFLKEKKYSDCAWEI

IFNK

171

Q9P0W0
QCKDFKWFLETVYPE

GALNT12

421

Q8IXK2
DFLAYDIACDEWKIL

ATRNL1

556

Q5VV63
TVWYFDAKERAAAKD

EGLN2

371

Q96KS0
VKVYEDWDCFKVNDI

MCMBP

241

Q9BTE3
EECIAWLKRFLEYGK

MR1

181

Q95460
QWYKDDLCALAFKVL

GFM2

361

Q969S9
ETIDYKDPCKAAVFW

TLL1

46

O43897
EENIDFWISCEEYKK

RGS4

86

P49798
LEFWIACEDYKKIKS

RGS5

91

O15539
ICFDAATKAVLWRYK

SNTG1

421

Q9NSN8
KYLSFEAEEKLAEWV

POGZ

1021

Q7Z3K3
LCASLSYEAEKIFKW

SMG1

221

Q96Q15
KEIWLLVDHLFKYAC

OCRL

736

Q01968
KYFLDQIEVCRDKGW

PIK3CG

1066

P48736
WSQCVELARLKFEKY

UBA6

696

A0AVT1
LLECTEAKKHCWYFE

VOPP1

16

Q96AW1
LDCAAKTVAEKWAYE

ZSWIM5

66

Q9P217
YFIAGVKKLDADWVE

GGCX

211

P38435
NWDCDYYDEKVVKLL

MARS2

381

Q96GW9
EIWDALKAAAYAAEA

UBTD1

66

Q9HAC8
LWELYDIFRNFCKDV

UGT2B11

116

O75310
PNAEWYFDRDVKCIK

RIOK2

256

Q9BVS4
YEKALVDCEWALKCD

TTC12

156

Q9H892
CKEYFWLLCKLVDNI

USP34

1731

Q70CQ2
NFVKSEWCKYELDFS

TLR2

706

O60603
VCYIFASEKKWAFSD

GEMIN4

421

P57678
DAFAKAIYERLFCWI

MYO1D

341

O94832
EYCLAVKELFCAKEW

MUSK

396

O15146
WFKCRYAKLTEAAEQ

NEFM

291

P07197