Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmitotic spindle midzone assembly

KIF23 PRC1 KIF4B

1.77e-05111003GO:0051256
GeneOntologyBiologicalProcessmitotic spindle elongation

KIF23 PRC1 KIF4B

2.36e-05121003GO:0000022
GeneOntologyBiologicalProcessspindle midzone assembly

KIF23 PRC1 KIF4B

3.87e-05141003GO:0051255
GeneOntologyBiologicalProcessspindle elongation

KIF23 PRC1 KIF4B

3.87e-05141003GO:0051231
HumanPhenoCongenital localized absence of skin

BMS1 LAMA3 ITGB4

1.67e-059313HP:0007383
DomainEGF_1

MUC3B GAS6 LAMA3 CUBN ITGB4 F9 SCUBE1 THBS4 MUC3A

9.23e-062551009PS00022
DomainEGF-like_CS

MUC3B GAS6 LAMA3 CUBN ITGB4 F9 SCUBE1 THBS4 MUC3A

1.11e-052611009IPR013032
DomainEGF_2

MUC3B GAS6 LAMA3 CUBN ITGB4 F9 SCUBE1 THBS4 MUC3A

1.26e-052651009PS01186
DomainCoagulation_fac_subgr_Gla_dom

GAS6 F2 F9

3.16e-05121003IPR017857
Domain-

GAS6 F2 F9

3.16e-051210034.10.740.10
DomainPH

DOCK11 ARHGAP10 TBC1D2 OBSCN PHETA1 SBF1 FERMT2 CYTH4

3.19e-052291008PF00169
DomainEGF

MUC3B GAS6 LAMA3 CUBN F9 SCUBE1 THBS4 MUC3A

3.84e-052351008SM00181
DomainGLA_1

GAS6 F2 F9

5.19e-05141003PS00011
DomainGLA_2

GAS6 F2 F9

5.19e-05141003PS50998
DomainGla

GAS6 F2 F9

5.19e-05141003PF00594
DomainGLA

GAS6 F2 F9

5.19e-05141003SM00069
DomainGLA_domain

GAS6 F2 F9

5.19e-05141003IPR000294
DomainEGF-like_dom

MUC3B GAS6 LAMA3 CUBN F9 SCUBE1 THBS4 MUC3A

5.77e-052491008IPR000742
DomainTranscrp_activ_Zfx/Zfy-dom

ZFX ZFY

8.48e-0531002IPR006794
Domain-

PYCR1 PYCR2

8.48e-05310021.10.3730.10
DomainZfx_Zfy_act

ZFX ZFY

8.48e-0531002PF04704
DomainP5CR_dimer

PYCR1 PYCR2

8.48e-0531002PF14748
DomainP5CR_dimer

PYCR1 PYCR2

8.48e-0531002IPR029036
DomainPH

DOCK11 ARHGAP10 TBC1D2 OBSCN PHETA1 SBF1 FERMT2 CYTH4

1.24e-042781008SM00233
DomainPH_DOMAIN

DOCK11 ARHGAP10 TBC1D2 OBSCN PHETA1 SBF1 FERMT2 CYTH4

1.27e-042791008PS50003
DomainPH_domain

DOCK11 ARHGAP10 TBC1D2 OBSCN PHETA1 SBF1 FERMT2 CYTH4

1.30e-042801008IPR001849
Domain6-PGluconate_DH_C-like

UGDH PYCR1 PYCR2

1.36e-04191003IPR008927
DomainP5CR

PYCR1 PYCR2

1.69e-0441002PS00521
DomainPyrroline-COOH_reductase

PYCR1 PYCR2

1.69e-0441002IPR000304
DomainEGF_Ca-bd_CS

GAS6 CUBN F9 SCUBE1 THBS4

1.74e-04971005IPR018097
DomainEGF_CA

GAS6 CUBN F9 SCUBE1 THBS4

1.91e-04991005PS01187
DomainTPR-like_helical_dom

ZFC3H1 TTC4 TOMM70 ANAPC5 CLUH TTC33 SMG6

2.57e-042331007IPR011990
DomainTPR_REGION

ZFC3H1 TTC4 TOMM70 ANAPC5 CLUH TTC33

2.61e-041651006PS50293
DomainTPR

ZFC3H1 TTC4 TOMM70 ANAPC5 CLUH TTC33

2.61e-041651006PS50005
DomainEGF_3

MUC3B GAS6 CUBN F9 SCUBE1 THBS4 MUC3A

2.71e-042351007PS50026
DomainEGF_CA

GAS6 CUBN F9 SCUBE1 THBS4

5.03e-041221005SM00179
DomainEGF-like_Ca-bd_dom

GAS6 CUBN F9 SCUBE1 THBS4

5.41e-041241005IPR001881
DomainIQ

MYH10 UBE3B OBSCN SCN8A

5.71e-04711004PF00612
DomainProC_N

PYCR1 PYCR2

5.86e-0471002IPR028939
DomainF420_oxidored

PYCR1 PYCR2

5.86e-0471002PF03807
Domain-

TTC4 TOMM70 ANAPC5 CLUH TTC33 SMG6

8.65e-0420710061.25.40.10
DomainIQ

MYH10 UBE3B OBSCN SCN8A

9.39e-04811004SM00015
DomainEGF_CA

GAS6 CUBN SCUBE1 THBS4

1.17e-03861004PF07645
Domain-

DOCK11 ARHGAP10 TBC1D2 OBSCN PHETA1 SBF1 FERMT2 CYTH4

1.20e-0339110082.30.29.30
DomainTPR-contain_dom

ZFC3H1 TTC4 TOMM70 ANAPC5 TTC33

1.28e-031501005IPR013026
DomainIQ_motif_EF-hand-BS

MYH10 UBE3B OBSCN SCN8A

1.39e-03901004IPR000048
DomainGrowth_fac_rcpt_

GAS6 LAMA3 CUBN SCUBE1 THBS4

1.52e-031561005IPR009030
DomainIQ

MYH10 UBE3B OBSCN SCN8A

1.57e-03931004PS50096
DomainEGF_dom

CUBN SCUBE1

1.81e-03121002IPR024731
DomainEGF_3

CUBN SCUBE1

1.81e-03121002PF12947
DomainASX_HYDROXYL

GAS6 CUBN F9 SCUBE1

2.05e-031001004PS00010
DomainPH_dom-like

DOCK11 ARHGAP10 TBC1D2 OBSCN PHETA1 SBF1 FERMT2 CYTH4

2.05e-034261008IPR011993
DomainSEA

MUC3B MUC3A

2.48e-03141002SM00200
DomainEGF-type_Asp/Asn_hydroxyl_site

GAS6 CUBN F9 SCUBE1

2.53e-031061004IPR000152
DomainLaminin_G

GAS6 LAMA3 THBS4

3.71e-03581003IPR001791
DomainEGF

GAS6 CUBN F9 THBS4

4.70e-031261004PF00008
DomainTPR

TTC4 TOMM70 ANAPC5 TTC33

5.11e-031291004SM00028
PathwayREACTOME_TRANSPORT_OF_GAMMA_CARBOXYLATED_PROTEIN_PRECURSORS_FROM_THE_ENDOPLASMIC_RETICULUM_TO_THE_GOLGI_APPARATUS

GAS6 F2 F9

1.34e-059783MM14614
PathwayREACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS

GAS6 F2 F9

1.90e-0510783M26977
PathwayREACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS

GAS6 F2 F9

2.60e-0511783M12484
PathwayREACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS

GAS6 F2 F9

2.60e-0511783MM14615
PathwayREACTOME_RHO_GTPASES_ACTIVATE_CIT

MYH10 PRC1 MYL12B

1.48e-0419783M27489
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

B4GALNT4 LRWD1 UBE3B OBSCN FYCO1 ITGB4 PPP1R26 PSME4 SBF1 PIK3C2B INF2 SCN8A TNK2 STK40 CYTH4 SMG6

1.87e-0711051041635748872
Pubmed

Genetic mapping in the mouse of Kif4, a gene encoding a kinesin-like motor protein.

ZFX ZFY KIF4B

9.01e-07710439196009
Pubmed

Praja1, a novel gene encoding a RING-H2 motif in mouse development.

ZFX ZFY PJA2

2.15e-06910439393880
Pubmed

The construction of human somatic cell hybrids containing portions of the mouse X chromosome and their use to generate DNA probes via interspersed repetitive sequence polymerase chain reaction.

F9 ZFX ZFY

5.60e-061210431916827
Pubmed

Identification and characterization of proteins interacting with SIRT1 and SIRT3: implications in the anti-aging and metabolic effects of sirtuins.

LAMA3 SBF1 UGDH HDAC2

7.02e-0641104419343720
Pubmed

In-vitro evaluation of anti-factor IXa aptamer on thrombin generation, clotting time, and viscoelastometry.

F2 F9

8.86e-062104219404534
Pubmed

Zfa is an expressed retroposon derived from an alternative transcript of the Zfx gene.

ZFX ZFY

8.86e-06210421691708
Pubmed

The structure of the Zfx gene on the mouse X chromosome.

ZFX ZFY

8.86e-06210428188262
Pubmed

Mapping the human ZFX locus to Xp21.3 by in situ hybridization.

ZFX ZFY

8.86e-06210422497060
Pubmed

Comparison of ZFY and ZFX gene structure and analysis of alternative 3' untranslated regions of ZFY.

ZFX ZFY

8.86e-06210422041734
Pubmed

Gene expression, X-inactivation, and methylation during spermatogenesis: the case of Zfa, Zfx, and Zfy in mice.

ZFX ZFY

8.86e-06210428318216
Pubmed

Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.

MUC3B MUC3A

8.86e-062104210973822
Pubmed

[Expression of Zfx in mouse testicular spermatogenic cells].

ZFX ZFY

8.86e-062104238602753
Pubmed

Differential rates of evolution for the ZFY-related zinc finger genes, Zfy, Zfx, and Zfa in the mouse genus Mus.

ZFX ZFY

8.86e-062104212716983
Pubmed

Intron/exon structure confirms that mouse Zfy1 and Zfy2 are members of the ZFY gene family.

ZFX ZFY

8.86e-06210429126493
Pubmed

Evolution of the Zfx and Zfy genes: rates and interdependence between the genes.

ZFX ZFY

8.86e-06210428487630
Pubmed

Zfx mutation results in small animal size and reduced germ cell number in male and female mice.

ZFX ZFY

8.86e-06210429187153
Pubmed

Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.

ZFX ZFY

8.86e-06210422265557
Pubmed

Initiation of transcription of the MUC3A human intestinal mucin from a TATA-less promoter and comparison with the MUC3B amino terminus.

MUC3B MUC3A

8.86e-062104212958310
Pubmed

Mouse Zfx protein is similar to Zfy-2: each contains an acidic activating domain and 13 zinc fingers.

ZFX ZFY

8.86e-06210422105457
Pubmed

The significance of circulating factor IXa in blood.

F2 F9

8.86e-062104215039440
Pubmed

MUC3 human intestinal mucin. Analysis of gene structure, the carboxyl terminus, and a novel upstream repetitive region.

MUC3B MUC3A

8.86e-06210429334251
Pubmed

Co‑expression of Axin and APC gene fragments inhibits colorectal cancer cell growth via regulation of the Wnt signaling pathway.

AXIN1 ANAPC5

8.86e-062104228731177
Pubmed

Transcription factor Zfx controls BCR-induced proliferation and survival of B lymphocytes.

ZFX ZFY

8.86e-062104219329779
Pubmed

Molecular cloning of cDNAs derived from a novel human intestinal mucin gene.

MUC3B MUC3A

8.86e-06210422393399
Pubmed

Associations of distinct variants of the intestinal mucin gene MUC3A with ulcerative colitis and Crohn's disease.

MUC3B MUC3A

8.86e-062104211289722
Pubmed

Chromosomal localization of ZFX--a human gene that escapes X inactivation--and its murine homologs.

ZFX ZFY

8.86e-06210421970799
Pubmed

Comparison of human ZFY and ZFX transcripts.

ZFX ZFY

8.86e-06210422308929
Pubmed

RNAi as a tool to control the sex ratio of mouse offspring by interrupting Zfx/Zfy genes in the testis.

ZFX ZFY

8.86e-062104228251288
Pubmed

Circ_0000520 contributes to triple-negative breast cancer progression through mediating the miR-1296/ZFX axis.

ZFX ZFY

8.86e-062104234324278
Pubmed

The MUC3 gene encodes a transmembrane mucin and is alternatively spliced.

MUC3B MUC3A

8.86e-062104210405327
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

MYH10 LRWD1 ARHGAP10 IARS1 BMS1 BEND3 PRC1 MDM2 TOMM70 STK40 MYL12B HDAC2

1.01e-058571041225609649
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

LRWD1 DOCK11 IARS1 ZFC3H1 PRC1 CENPP SBF1 UGDH FERMT2 MYL12B CLUH

1.14e-057241041136232890
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

NUDT19 MYH10 BEND3 TOMM70 GCAT PYCR1 PYCR2 MYL12B CLUH

2.53e-05515104931617661
Pubmed

USP19 deubiquitinates HDAC1/2 to regulate DNA damage repair and control chromosomal stability.

USP19 HDAC2

2.65e-053104227517492
Pubmed

PYCR1 and PYCR2 Interact and Collaborate with RRM2B to Protect Cells from Overt Oxidative Stress.

PYCR1 PYCR2

2.65e-053104226733354
Pubmed

Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.

MUC3B MUC3A

2.65e-053104218163520
Pubmed

Frequent amplification of ORAOV1 gene in esophageal squamous cell cancer promotes an aggressive phenotype via proline metabolism and ROS production.

PYCR1 PYCR2

2.65e-053104224930674
Pubmed

Characterization of the ZFX family of transcription factors that bind downstream of the start site of CpG island promoters.

ZFX ZFY

2.65e-053104232406922
Pubmed

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin.

MUC3B MUC3A

2.65e-053104210512748
Pubmed

The life cycle of coagulation factor VIII in view of its structure and function.

F2 F9

2.65e-05310429834200
Pubmed

PAK1 and aPKCzeta regulate myosin II-B phosphorylation: a novel signaling pathway regulating filament assembly.

MYH10 PRKCZ

2.65e-053104216611744
Pubmed

Blockade of ZFX Alleviates Hypoxia-Induced Pulmonary Vascular Remodeling by Regulating the YAP Signaling.

ZFX ZFY

2.65e-053104238310188
Pubmed

X-radiation inhibits histone deacetylase 1 and 2, upregulates Axin expression and induces apoptosis in non-small cell lung cancer.

AXIN1 HDAC2

2.65e-053104223110995
Pubmed

Functional specialization in proline biosynthesis of melanoma.

PYCR1 PYCR2

2.65e-053104223024808
Pubmed

Zfy gene expression patterns are not compatible with a primary role in mouse sex determination.

ZFX ZFY

2.65e-05310422480529
Pubmed

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.

LAMA3 ITGB4

2.65e-053104215316072
Pubmed

Genetic dissection of mammalian fertility pathways.

ZFX ZFY

2.65e-053104212479614
Pubmed

Genetic analysis of Pycr1 and Pycr2 in mice.

PYCR1 PYCR2

2.65e-053104233734376
Pubmed

X chromosome genes and premature ovarian failure.

ZFX ZFY

2.65e-053104211299520
Pubmed

Isolation of monochromosomal hybrids for mouse chromosomes 3, 6, 10, 12, 14, and 18.

ZFX ZFY

2.65e-05310429060403
Pubmed

Molecular reconstruction and homology modelling of the catalytic domain of the common ancestor of the haemostatic vitamin-K-dependent serine proteinases.

F2 F9

2.65e-05310428707309
Pubmed

YAC clone contigs surrounding the Zfx and Pola loci on the mouse X chromosome.

ZFX ZFY

2.65e-05310428406471
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZSWIM8 MYH10 KIF23 U2SURP BMS1 BEND3 RPS26 SBF1 CLUH HDAC2

2.72e-056531041022586326
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

MYH10 IARS1 U2SURP RPS26 SNX16 PRC1 AXIN1 UGDH PYCR1 ANAPC5 HDAC2

3.16e-058091041132129710
Pubmed

ZFX controls propagation and prevents differentiation of acute T-lymphoblastic and myeloid leukemia.

ZFX ZFY

5.29e-054104224485662
Pubmed

Identification of a novel population in high-grade oligodendroglial tumors not deleted on 1p/19q using array CGH.

MDM2 PIK3C2B

5.29e-054104222825724
Pubmed

Differential regulation of alpha6beta4 integrin by PKC isoforms in murine skin keratinocytes.

ITGB4 PRKCZ

5.29e-054104214715240
Pubmed

A BEN-domain-containing protein associates with heterochromatin and represses transcription.

BEND3 HDAC2

5.29e-054104221914818
Pubmed

Essential roles of KIF4 and its binding partner PRC1 in organized central spindle midzone formation.

KIF23 PRC1

5.29e-054104215297875
Pubmed

MDM2 Inhibits Axin-Induced p53 Activation Independently of its E3 Ligase Activity.

MDM2 AXIN1

5.29e-054104223826318
Pubmed

Selective inhibition of histone deacetylase 2 induces p53-dependent survivin downregulation through MDM2 proteasomal degradation.

MDM2 HDAC2

5.29e-054104225605253
Pubmed

Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling.

LAMA3 ITGB4

5.29e-054104222673183
Pubmed

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

ZFX ZFY

5.29e-054104217448993
Pubmed

Gene expression profiling during the embryonic development of mouse brain using an oligonucleotide-based microarray system.

PRKCZ STK40

5.29e-054104215893606
Pubmed

HDAC2 Regulates Site-Specific Acetylation of MDM2 and Its Ubiquitination Signaling in Tumor Suppression.

MDM2 HDAC2

5.29e-054104230818224
Pubmed

A conserved acetylation switch enables pharmacological control of tubby-like protein stability.

RAD18 BEND3 TTC4 PJA2 SBF1 GCAT

5.84e-05223104633187986
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

RAD18 KIF23 CIP2A BEND3 ZFC3H1 PRC1 FANCM CENPP

6.74e-05453104829656893
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

MYH10 IARS1 U2SURP BMS1 RPS26 ZFC3H1 PRC1 PYCR1 PYCR2 HDAC2

7.00e-057311041029298432
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

DOCK11 IARS1 TBC1D2 BMS1 OBSCN RPS26 THBS4 R3HCC1L SCN8A ITPRIPL1

7.40e-057361041029676528
Pubmed

Interactomes of SARS-CoV-2 and human coronaviruses reveal host factors potentially affecting pathogenesis.

TOMM70 PYCR1 PYCR2

8.06e-0528104334232536
Pubmed

The human gene ZFP161 on 18p11.21-pter encodes a putative c-myc repressor and is homologous to murine Zfp161 (Chr 17) and Zfp161-rs1 (X Chr).

ZFX ZFY

8.80e-05510429244432
Pubmed

HDAC6 promotes hepatocellular carcinoma progression by inhibiting P53 transcriptional activity.

MDM2 TNK2

8.80e-055104223402884
Pubmed

IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa.

LAMA3 ITGB4

8.80e-05510429271670
Pubmed

The microtubule-associated protein PRC1 promotes early recurrence of hepatocellular carcinoma in association with the Wnt/β-catenin signalling pathway.

PRC1 AXIN1

8.80e-055104226941395
Pubmed

Maintenance of X inactivation of the Rps4, Zfx, and Ube1 genes in a mouse in vitro system.

ZFX ZFY

8.80e-05510427681608
Pubmed

Asymmetric division of contractile domains couples cell positioning and fate specification.

MYH10 PRKCZ

8.80e-055104227487217
Pubmed

Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.

MYH10 ITGB4

8.80e-055104225006807
Pubmed

Chromosome mapping and expression of a putative testis-determining gene in mouse.

ZFX ZFY

8.80e-05510422563174
Pubmed

miR-17-5p/20a are important markers for gastric cancer and murine double minute 2 participates in their functional regulation.

TP53INP1 MDM2

8.80e-055104223333058
Pubmed

MSG1 (melanocyte-specific gene 1): mapping to chromosome Xq13.1, genomic organization, and promoter analysis.

ZFX ZFY

8.80e-05510429721210
Pubmed

Laminin 5 regulates polycystic kidney cell proliferation and cyst formation.

LAMA3 ITGB4

8.80e-055104216870608
Pubmed

Zfx facilitates tumorigenesis caused by activation of the Hedgehog pathway.

ZFX ZFY

8.80e-055104225164012
Pubmed

The ribosomal protein S26 regulates p53 activity in response to DNA damage.

RPS26 MDM2

8.80e-055104223728348
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

ZSWIM8 DOCK11 F2 ZFX ZFY SCUBE1 NWD2 SCN8A

9.35e-05475104831040226
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

DOCK11 ARHGAP10 NCKAP5 MDM2 USP19 TAF4B FERMT2

1.14e-04363104714691545
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZSWIM8 RAD18 ARHGAP10 GAS6 BEND3 MDM2 PJA2 PRPF40B GCAT TAF4B ANAPC5 HDAC2

1.29e-0411161041231753913
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

ZSWIM8 IARS1 LAMA3 RPS26 MDM2 PJA2 SBF1 BUB1 MYL12B

1.32e-04639104923443559
Pubmed

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

ITGB4 FERMT2

1.32e-046104225808491
Pubmed

KIF14 and citron kinase act together to promote efficient cytokinesis.

KIF23 PRC1

1.32e-046104216431929
Pubmed

Sequence and expression of murine cDNAs encoding Xlr3a and Xlr3b, defining a new X-linked lymphocyte-regulated Xlr gene subfamily.

ZFX ZFY

1.32e-04610427821804
Pubmed

Junctional Epidermolysis Bullosa

LAMA3 ITGB4

1.32e-046104220301304
Pubmed

Polo-like kinase 1 directs assembly of the HsCyk-4 RhoGAP/Ect2 RhoGEF complex to initiate cleavage furrow formation.

KIF23 PRC1

1.32e-046104219468300
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

NUDT19 MYH10 CIP2A BMS1 BEND3 TTC4 USP19 TOMM70 INF2 BUB1 PYCR1 PYCR2 CLUH SMG6

1.49e-0414961041432877691
Pubmed

VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo.

F2 F9

1.84e-047104229321368
Pubmed

Myosin regulatory light chains are required to maintain the stability of myosin II and cellular integrity.

MYH10 MYL12B

1.84e-047104221126233
Pubmed

Lens placode planar cell polarity is dependent on Cdc42-mediated junctional contraction inhibition.

MYH10 PRKCZ

1.84e-047104226902112
Pubmed

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

ZFX ZFY

1.84e-04710428378320
Pubmed

Embryonic growth and the evolution of the mammalian Y chromosome. II. Suppression of selfish Y-linked growth factors may explain escape from X-inactivation and rapid evolution of Sry.

ZFX ZFY

1.84e-04710427928394
Pubmed

An evaluation of the inactive mouse X chromosome in somatic cell hybrids.

ZFX ZFY

1.84e-04710428460399
InteractionCUL4A interactions

MYH10 KIF23 LRWD1 PDE6A IARS1 OBSCN ZNF407 MDM2 TTC4 USP19 PJA2 PSME4 UGDH FERMT2 ANAPC5 HDAC2

3.93e-068549916int:CUL4A
InteractionTOP3B interactions

NUDT19 MYH10 KIF23 B4GALNT4 LRWD1 IARS1 UBE3B OBSCN FYCO1 ITGB4 PPP1R26 PSME4 SBF1 PIK3C2B INF2 SCN8A TNK2 STK40 CYTH4 SMG6

2.61e-0514709920int:TOP3B
InteractionFXR1 interactions

MYH10 KIF23 LRWD1 FYCO1 GRIK3 PRC1 AXIN1 SBF1 PYCR1 PYCR2 CLUH HDAC2 SMG6

2.77e-056799913int:FXR1
InteractionSQSTM1 interactions

NUDT19 RAD18 KIF23 TP53INP1 NHSL2 CIP2A GAS6 RPS26 PRC1 USP19 AXIN1 PJA2 PIK3C2B BUB1 TNK2 PRKCZ PYCR2 FERMT2

3.64e-0512579918int:SQSTM1
InteractionKIF4B interactions

PRC1 KIF4B HDAC2

4.02e-0514993int:KIF4B
GeneFamilyGla domain containing

GAS6 F2 F9

1.18e-05136431250
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

DOCK11 PHETA1 SBF1 FERMT2 CYTH4

8.08e-04206645682
CoexpressionMARKEY_RB1_ACUTE_LOF_UP

KIF23 CIP2A GAS6 PRC1 MDM2 BUB1 KIF4B ANAPC5 HDAC2

4.26e-072401029MM976
CoexpressionMARKEY_RB1_ACUTE_LOF_UP

KIF23 CIP2A GAS6 PRC1 MDM2 BUB1 ANAPC5 HDAC2

4.19e-062371028M15606
CoexpressionTRAVAGLINI_LUNG_ALVEOLAR_EPITHELIAL_TYPE_1_CELL

DOCK11 TBC1D2 GAS6 LAMA3 NCKAP5 INF2 PRKCZ FERMT2 MYL12B

2.25e-053911029M41659
CoexpressionMARTORIATI_MDM4_TARGETS_FETAL_LIVER_DN

PHETA1 CUBN PRC1 ALG2 USP19 ZFX PJA2 BUB1 FERMT2 ANAPC5

3.55e-0551910210M3395
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

DOCK11 CIP2A SNX16 DPP8 CENPP PJA2 TOMM70 BUB1 HDAC2 TTC33

3.79e-0552310210M12707
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_UP

DOCK11 CIP2A SNX16 DPP8 CENPP PJA2 TOMM70 BUB1 HDAC2 TTC33

4.51e-0553410210MM1054
CoexpressionTANG_SENESCENCE_TP53_TARGETS_DN

KIF23 PRC1 ZFY BUB1

6.80e-05561024M6171
CoexpressionLE_EGR2_TARGETS_UP

KIF23 CIP2A PRC1 BUB1 HDAC2

6.85e-051091025MM1148
CoexpressionLE_EGR2_TARGETS_UP

KIF23 CIP2A PRC1 BUB1 HDAC2

7.16e-051101025M12804
CoexpressionGSE14415_TCONV_VS_FOXP3_KO_INDUCED_TREG_DN

KIF23 PSPH PRC1 CENPP BUB1 ANAPC5

8.76e-051851026M2965
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 RAD18 KIF23 CIP2A PRC1 CENPP BUB1

1.36e-071691037563c267edaade0e5df192ad953801ef9768d4270
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 KIF23 CIP2A PRC1 CENPP BUB1 UGDH

3.85e-07197103729b0a5927f80455eef7b793feabef69fba1a3df1
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

GAS6 LAMA3 NCKAP5 SCUBE1 RHOBTB2 PRKCZ MUC3A

3.99e-07198103775bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellAT1-AT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

GAS6 LAMA3 NCKAP5 FYCO1 PRKCZ FERMT2

2.72e-061691036815474855a70498a74e52f6583113c63b7267a0c
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CIP2A PRC1 AXIN1 CENPP BUB1

3.22e-0617410366c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCellAT1-AT2_cells-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

GAS6 LAMA3 NCKAP5 RHOBTB2 PRKCZ FERMT2

3.32e-061751036bdd85ba280648a0283c1984662a34c7b840f64dd
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF23 CIP2A ZNF407 F2 CENPP BUB1

3.44e-061761036581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD18 KIF23 LRWD1 CIP2A PRC1 BUB1

4.04e-061811036b203b616584cdbd0bbb0e382b2916d0bd49d3526
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD18 KIF23 LRWD1 CIP2A PRC1 BUB1

4.04e-061811036c748c16fd20d1949d33ff6290dc9d9016c4dc86c
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

TP53INP1 GAS6 FAM30A BUB1 TAF4B ACOXL

4.30e-061831036130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

TP53INP1 GAS6 FAM30A BUB1 TAF4B ACOXL

4.30e-0618310362c016bb59f131a0e821853b085289a3583f0a729
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK11 GAS6 LAMA3 NCKAP5 SCUBE1 INF2

4.44e-061841036c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

GAS6 LAMA3 NCKAP5 SCUBE1 INF2 PRKCZ

4.44e-061841036cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOCK11 GAS6 LAMA3 NCKAP5 SCUBE1 INF2

4.44e-0618410361ed558a88215b248431c524ea16f13d9022ae98c
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

GAS6 LAMA3 NCKAP5 SCUBE1 INF2 PRKCZ

4.44e-061841036bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

ELP5 ARHGAP10 MDM2 ZFX MYL12B TTC33

4.72e-061861036ed9b1a784f67e8a297e2a10993a6d97df60581ac
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-Plasma_cell|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TP53INP1 GAS6 FAM30A BUB1 PYCR1 TAF4B

4.87e-061871036d2296f2722a24b289fed7e6cfdc2105608437c3e
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_B-Plasma_cell-B_c05-MZB1-XBP1|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TP53INP1 GAS6 FAM30A BUB1 PYCR1 TAF4B

4.87e-06187103606a0f0a27569af89f86ed8cddb608454a3d40cc5
ToppCellFibroblast-E_(Early_Fibroblastic_progenitor)|World / shred on cell class and cell subclass (v4)

MYH10 RAD18 KIF23 PRC1 CENPP BUB1

5.02e-061881036be3db9768364568f44e32ae6b3bf99e49b0978bb
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 KIF23 CIP2A PRC1 CENPP BUB1

5.02e-06188103695d0a796d62ce6d121e2028c378faffc14b35275
ToppCellMatrixFB-Fibroblast-E_(Early_Fibroblastic_progenitor)|MatrixFB / shred on cell class and cell subclass (v4)

RAD18 KIF23 CIP2A PRC1 CENPP BUB1

5.02e-061881036b240ea20750ffb825cb5fe41d06c632233406ab6
ToppCellInt-URO-Lymphocyte-T_NK-T_NK_proliferative|Int-URO / Disease, Lineage and Cell Type

KIF23 CIP2A PRC1 BUB1 SCN8A KIF4B

5.33e-061901036005967c540418b85311308072a07c684f4296aef
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TBC1D2 GAS6 LAMA3 NCKAP5 SCUBE1 PRKCZ

5.50e-061911036a15e34ad7dbf3f2f13d5e23ce3ffb6d08fd1f9f0
ToppCellE17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RAD18 KIF23 CIP2A PRC1 CENPP BUB1

5.50e-061911036f764cc21fef87ebad765011098f647ae1bdf6158
ToppCelldroplet-Skin-nan-21m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD18 KIF23 CIP2A PRC1 CENPP BUB1

5.66e-06192103696f23d6e8604d1cb24910d3118d8171b57c93e14
ToppCellProliferating|World / shred by cell class for mouse tongue

RAD18 KIF23 CIP2A PRC1 CENPP BUB1

5.66e-061921036f081f3f957cc782294e118fcc1055f6a4264ee98
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYH10 KIF23 CIP2A PRC1 CENPP BUB1

5.83e-061931036a332dfdcc48c405020014e644aa4d14fda98cc86
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RAD18 KIF23 CIP2A FANCM CENPP BUB1

5.83e-0619310364b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCelldroplet-Tongue-nan-24m-Epithelial-proliferating|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD18 KIF23 CIP2A PRC1 CENPP BUB1

5.83e-061931036f20b90e3f3f5c9a1ae51c5ebe6d3adb954a142f2
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS6 LAMA3 NCKAP5 SCUBE1 RHOBTB2 PRKCZ

6.19e-06195103668f4cc84b5ae7f4159b780c78e4b66c94211779a
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS6 LAMA3 NCKAP5 SCUBE1 RHOBTB2 PRKCZ

6.19e-0619510362a1863f4b9fe73c30b0b1acf9b12fc98ef65040f
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GAS6 LAMA3 NCKAP5 SCUBE1 RHOBTB2 PRKCZ

6.37e-061961036eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

KIF23 PRC1 CENPP GCAT BUB1 PYCR1

6.56e-061971036189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCellmild-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TP53INP1 GAS6 BUB1 PYCR1 TAF4B ACOXL

6.56e-06197103621085d5e27b5a23a241a933058bb89f8a1fcf198
ToppCellMS-cycling-|MS / Condition, Cell_class and T cell subcluster

KIF23 CIP2A PRC1 CENPP BUB1 PYCR1

6.75e-06198103619c5d6b65de490118574b1f86b45c58b3a51df7f
ToppCellMS-cycling|MS / Condition, Cell_class and T cell subcluster

KIF23 CIP2A PRC1 CENPP BUB1 PYCR1

6.75e-0619810360c22f2cc0e5ca91cabcd4aac2b9ef05af47e967f
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NHSL2 ZNF407 PABPC5 THBS4 SBF1 FERMT2

7.15e-062001036f7c3a8f5ac156c05ad7335d6d142c154c7d86449
ToppCellEndothelial-H_(cycle)|World / shred on cell class and cell subclass (v4)

KIF23 CIP2A PABPC5 PRC1 BUB1

1.45e-0513310358e3005114761feee028c496cc739e607b35d7831
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

ZSWIM8 MYH10 PPP1R26 BUB1 UGDH

2.51e-051491035651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

TBC1D2 OFCC1 OBSCN MUC3A

3.08e-05771034a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCellLAM-Lymphoid-B-cell-2|LAM / Condition, Lineage and Cell class

DPEP1 TP53INP1 GAS6 FAM30A PYCR1

3.53e-0516010350060c2b3304f411c682aa2ba20bcf80f346d2403
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CIP2A PRC1 GCAT BUB1

3.97e-051641035249d8f75a64bce7db52ce0c563f496b9edf602a6
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-CD1c-positive_myeloid_dendritic_cell-DC2_(CD1c+_dendritic_cell)-DC2_L.1.2.1.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPP8 AXIN1 R3HCC1L TAF4B CYTH4

4.09e-05165103576abebe80e5f8bf44825bb619ae86fcb6f66ffeb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 CIP2A PRC1 BUB1 KIF4B

4.09e-051651035eec2d327c94832d1390314c93ef6a2be4648478b
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIP2A CENPP BUB1 SCN8A

4.09e-05165103596f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CIP2A LAMA3 PRC1 BUB1

4.58e-051691035a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF23 CIP2A PRC1 CENPP BUB1

4.58e-051691035e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CIP2A LAMA3 PRC1 BUB1

4.58e-051691035195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

LAMA3 NCKAP5 ZFY PRKCZ FERMT2

4.71e-051701035e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 PRC1 F9 PIK3C2B BUB1

4.71e-051701035e08a6c5ac34c456da8c7318f104e06fca585be1f
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TP53INP1 UBE3B BEND3 ACOXL DRC3

4.85e-051711035d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CIP2A PRC1 CENPP BUB1

4.85e-051711035621f9da0bfa09c86fc89fd26919403e94cd56d2b
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CIP2A PRC1 CENPP GCAT BUB1

4.98e-0517210351171e754fd503a0c1152162fcc12a115088a08c7
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 PRC1 CENPP BUB1 UGDH

4.98e-051721035c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellLymphoid-Lymphoid-B_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

KIF23 IARS1 PRC1 GCAT SCN8A

4.98e-051721035f39822afcc35f0fbf68b8ffd1894e4b6c8d7a80c
ToppCellBL-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

GAS6 FAM30A BUB1 PYCR1 ACOXL

5.12e-05173103590700a876d997f7c0f7b3899dffcda7fdafee547
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

CIP2A PHETA1 NCKAP5 PRC1 PRPF40B

5.12e-05173103562e0c18cfed9645e34a9d7029c94a8554f773714
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

B4GALNT4 OBSCN ITGB4 MUC3A CLUH

5.26e-051741035207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 PRC1 CENPP BUB1 UGDH

5.41e-051751035a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCellAT1_cells-HP_01|World / lung cells shred on cell class, cell subclass, sample id

GAS6 LAMA3 NCKAP5 SCUBE1 MUC3A

5.56e-051761035458720776b0151cd55acc352d509599cb62f0ca8
ToppCellfacs-Lung-Endomucin-24m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 BEND3 PKD1L2 CENPP CYTH4

6.02e-051791035e520eadde4f1b7fb868dbbe94c4d62b3776c55eb
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CIP2A PRC1 CENPP BUB1

6.02e-05179103554191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_G2M|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 NHSL2 PRC1 BUB1 PRKCZ

6.02e-051791035df4d0b2fe47d2c7def729b3217cb01ced01495ff
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD18 NCKAP5 PRC1 CENPP BUB1

6.02e-0517910354166c4e1a8748a79ac6a11fd0b97c5344be2321b
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CIP2A PRC1 CENPP BUB1

6.18e-0518010355e1680088065be14447d5d5465f91f7edd071a1e
ToppCellHippocampus-Macroglia-POLYDENDROCYTE-P5|Hippocampus / BrainAtlas - Mouse McCarroll V32

RPS26 PRC1 BUB1 ANAPC5 HDAC2

6.18e-05180103544988c34861df359a68376500c42a64fbcc4b431
ToppCellcontrol-Lymphoid-NKT-proliferating|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KIF23 CIP2A CLDN25 PRC1 BUB1

6.18e-051801035535535a67b3f3320bad2f98b1bc98a7b0ee77840
ToppCellP28-Endothelial-proliferative_endothelial_cell-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF23 CIP2A PRC1 CENPP BUB1

6.34e-051811035e482fd116c00ff4d8db7be3c06b1bd1ffa2d479d
ToppCellP28-Endothelial-proliferative_endothelial_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

KIF23 CIP2A PRC1 CENPP BUB1

6.34e-0518110352be3d44619adb25d339e7a27b500a56e07e8de01
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSEN2 CIP2A F2 ITGB4 PIK3C2B

6.34e-0518110354ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCellBAL-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

BMS1 FYCO1 PPP1R26 PRPF40B TAF4B

6.34e-051811035f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCellLymphoid-Lymphoid-T_cells_(cycle)|Lymphoid / shred on cell class and cell subclass (v4)

KIF23 CIP2A PRC1 CENPP BUB1

6.34e-051811035b6b41cd5d43543fe7a093033dae52a789199db0e
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 PRC1 CENPP SLAMF6 PRKCZ

6.51e-0518210353948422707d6d5e021bcd7158e2eb69143613f62
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 PRC1 CENPP SLAMF6 PRKCZ

6.51e-051821035fe46819c153a81911864473badc794f243705f98
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

GAS6 LAMA3 NCKAP5 SCUBE1 PRKCZ

6.51e-051821035e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellNS-control-d_0-4-Lymphoid-NKT-proliferating|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF23 CIP2A CLDN25 PRC1 BUB1

6.51e-051821035f623c47e7806181d09f126066a952162ce49a306
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

TBC1D2 LAMA3 NCKAP5 RHOBTB2 PRKCZ

6.68e-0518310357b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

GAS6 LAMA3 NCKAP5 RHOBTB2 PRKCZ

6.68e-05183103531fef35ecf30162662f24d335d8f0cceacc07039
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYH10 FAM30A BUB1 PYCR1 ACOXL

6.68e-051831035dd15e1463a0d57d14800de0df0645c81c56926ae
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_plasma|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

MYH10 FAM30A BUB1 PYCR1 ACOXL

6.68e-0518310358ace19c38b89556d2504258a63aa5a2b14f5cd36
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KIF23 CIP2A PRC1 CENPP BUB1

6.68e-051831035e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5|Striatum / BrainAtlas - Mouse McCarroll V32

KIF23 RPS26 PRC1 CENPP BUB1

6.68e-051831035f20b0d71f857ac35868fd80531050ad8b6091716
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

GAS6 LAMA3 NCKAP5 RHOBTB2 PRKCZ

6.68e-051831035c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCellTCGA-Uvea-Primary_Tumor-Uveal_Melanoma-Epithelioid_Cell-4|TCGA-Uvea / Sample_Type by Project: Shred V9

TP53INP1 DOCK11 SNX16 MDM2 PSME4

6.86e-0518410359c56753e5e668be888662e4713cf4ce44e6c58fb
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CIP2A PRC1 CENPP BUB1

6.86e-0518410356b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF23 CIP2A PRC1 CENPP BUB1

6.86e-051841035e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

DPEP1 TP53INP1 GAS6 FAM30A PYCR1

6.86e-0518410356f70d8f8ab8362d51f8a58735d42223e06566397
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIF23 CIP2A PABPC5 PRC1 BUB1

6.86e-051841035d1e0e3b0eed2db8a5b7e3d6f81294667e4ba64e5
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIF23 CIP2A GRIK3 PRC1 BUB1

7.04e-051851035282b3de8850f3c21704339e8d8737b432a43441a
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

KIF23 CIP2A PRC1 CENPP BUB1

7.04e-0518510359766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KIF23 CIP2A LAMA3 CENPP BUB1

7.04e-05185103530e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCelldroplet-Spleen-SPLEEN-1m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 PRC1 THBS4 GCAT BUB1

7.04e-051851035736bf89a7a1a840ab6920060f2d98598332065a0
ToppCell10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic|bone_marrow / Manually curated celltypes from each tissue

KIF23 CIP2A GAS6 PRC1 BUB1

7.04e-0518510359d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell10x5'-Liver-Lymphocytic_B_plasma|Liver / Manually curated celltypes from each tissue

DPEP1 TP53INP1 GAS6 FAM30A PYCR1

7.22e-051861035a2c7430781f432c9c90ac4d620f4518ff767a223
ToppCellLAM-Lymphoid-B-cell-2|Lymphoid / Condition, Lineage and Cell class

DPEP1 TP53INP1 GAS6 FAM30A PYCR1

7.22e-051861035bcfe0bf2f7f745146b74496a4fcfccd869ad7c6f
ToppCellfacs-Skin-Telogen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIP2A PRC1 CENPP BUB1

7.22e-0518610359feef5936985e936b3d88f9d1bb012abb6468570
ToppCellmild-Lymphocytic-Plasmablast|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

TP53INP1 FAM30A BUB1 PYCR1 ACOXL

7.22e-051861035060510c21b1e0889b7a6eeb15821b9e2f03a0f99
ToppCellIPF-Epithelial-ATI|Epithelial / Disease state, Lineage and Cell class

GAS6 LAMA3 NCKAP5 INF2 RHOBTB2

7.22e-051861035d436ee6cabbde8553ec5e6e55022274090d9f41a
ToppCellfacs-Skin-Telogen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIP2A PRC1 CENPP BUB1

7.22e-05186103589f5b06bc56674af304912d481ac697c7c870904
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF23 CIP2A PRC1 BUB1 PYCR1

7.40e-0518710354d12c70c8ed922fbc8f7b139145611203735cab4
DrugGanciclovir [82410-32-0]; Down 200; 15.6uM; HL60; HT_HG-U133A

KIF23 PSEN2 ARHGAP10 UBE3B GAS6 ZNF407 PSPH MDM2 ITGB4

2.82e-0719710393030_DN
Diseasehemophilia B (is_implicated_in)

F2 F9

1.14e-0521002DOID:12259 (is_implicated_in)
Diseaseautosomal recessive cutis laxa type IIB (implicated_via_orthology)

PYCR1 PYCR2

1.14e-0521002DOID:0070137 (implicated_via_orthology)
DiseaseEpidermolysis Bullosa Progressiva

LAMA3 ITGB4

6.79e-0541002C0079297
DiseaseHerlitz Disease

LAMA3 ITGB4

6.79e-0541002C0079683
DiseaseAnhydrotic Ectodermal Dysplasias

BMS1 ITGB4

6.79e-0541002C1706004
DiseaseAdult junctional epidermolysis bullosa (disorder)

LAMA3 ITGB4

1.13e-0451002C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

LAMA3 ITGB4

1.13e-0451002C2608084
DiseaseHidrotic Ectodermal Dysplasia

BMS1 ITGB4

1.13e-0451002C0162361
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

LAMA3 ITGB4

1.13e-0451002DOID:0060738 (implicated_via_orthology)
DiseaseEctodermal Dysplasia

BMS1 ITGB4

1.69e-0461002C0013575
DiseaseJunctional Epidermolysis Bullosa

LAMA3 ITGB4

1.69e-0461002C0079301
DiseaseAplasia Cutis Congenita

BMS1 ITGB4

1.69e-0461002C0282160
Diseasejunctional epidermolysis bullosa (is_implicated_in)

LAMA3 ITGB4

2.36e-0471002DOID:3209 (is_implicated_in)
DiseaseAdenocarcinoma of large intestine

MDM2 AXIN1 PRKCZ STK40

3.25e-04961004C1319315
Diseaseovarian serous carcinoma

LAMA3 PRC1 ACOXL

5.16e-04461003EFO_1001516
DiseaseThrombus

GAS6 F2 F9

5.16e-04461003C0087086
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

MUC3B ARHGAP10 KIF4B MUC3A

5.44e-041101004EFO_0803335
DiseaseThrombosis

GAS6 F2 F9

6.21e-04491003C0040053
DiseaseThromboembolism

GAS6 F2

7.34e-04121002C0040038
DiseaseProteinuria

CUBN SMG6

1.16e-03151002HP_0000093
DiseaseMAJOR AFFECTIVE DISORDER 2

PHETA1 PRKCZ

1.50e-03171002C1839839
DiseaseC-X-C motif chemokine 16 measurement

FYCO1 ACOXL

1.68e-03181002EFO_0010911
DiseaseAdenocarcinoma of prostate

AXIN1 HDAC2

2.08e-03201002C0007112
DiseaseCardiac Hypertrophy

GAS6 PRKCZ HDAC2

2.76e-03821003C1383860
DiseaseCardiomegaly

GAS6 PRKCZ HDAC2

2.76e-03821003C0018800

Protein segments in the cluster

PeptideGeneStartEntry
SEEFKDEIVNDRDCS

SMG6

71

Q86US8
EACRLTDTDAAIAED

BUB1

696

O43683
TREDQCSELFDDEAI

ADAM7

506

Q9H2U9
DREEVATVCKAFESF

CLDN25

56

C9JDP6
CVTASVDDIQFEETA

ACOT12

51

Q8WYK0
ADVFAQIDCFESAEE

CYTH4

41

Q9UIA0
HCTAEEVFASEDESE

BMS1

581

Q14692
ECSELSEFVSRAEER

CENPP

146

Q6IPU0
CDTDVFATFEGDDVV

ACOXL

366

Q9NUZ1
DDVAQDEDDFEICSI

TNK2

636

Q07912
DDFDCRREDSEVVSI

NWD2

1181

Q9ULI1
VFDQTCVDFEVESVG

R3HCC1L

276

Q7Z5L2
DREEDSSSCIDIQEV

RAD18

416

Q9NS91
VGFCTEVEEDLIDAV

PYCR1

156

P32322
RVCEVEFVFSEGSEA

LRWD1

481

Q9UFC0
VETEAEDAALDCSVN

BEND3

21

Q5T5X7
ELDVSVREEEVSCSG

ANAPC5

191

Q9UJX4
FIGDAVTDDERCIDA

ARHGAP10

71

A1A4S6
DELVRCAVDAATAYE

LAMA3

2166

Q16787
DVAFRICAVREAFEE

NUDT19

121

A8MXV4
AVCVNRSAVEEEDTE

GTSF1L

61

Q9H1H1
DDAVFDIITDEELCQ

FYCO1

1276

Q9BQS8
LDEREAFCESEFAVN

C17orf58

201

Q2M2W7
SSSVIESDEECAEIV

FANCM

826

Q8IYD8
VAEAEGEACAAREAA

CCDC194

166

A0A1B0GVG4
SSCEFAVEQVDLDVV

MUC3A

3006

Q02505
TEEDEHFCDFVDILT

PDE6A

156

P16499
EEKCSFEEAREVFEN

F9

66

P00740
HSEEDIDRCVEAFVE

GCAT

396

O75600
EVVVRCSFRDEDDDC

ITGB4

666

P16144
FCDIGESVEETIRRE

NUDT13

231

Q86X67
IAANCDIADERFDAT

CHRFAM7A

21

Q494W8
ASDAQECTLEEVVER

INF2

326

Q27J81
DTCVEDVAFQAAVSE

PKD1L2

866

Q7Z442
EDAETCDVAGAVVRF

SBF1

816

O95248
FEVSEERDEEVAAFC

PIK3C2B

326

O00750
VDAEVTADEDVEFSC

OBSCN

4166

Q5VST9
TADEDVEFSCEVSRA

OBSCN

4171

Q5VST9
QCATEVSREDDDRIF

OFCC1

106

Q8IZS5
VCFSSFEEATKAVDE

PABPC5

346

Q96DU9
TCEFVESFVDDLIEA

ITPRIPL1

186

Q6GPH6
EDSQDCSRDFVEIRE

CUBN

1786

O60494
VCVEFRDSDESDASA

DOCK11

666

Q5JSL3
VEELCSREEAREVFE

GAS6

66

Q14393
FDCGVVFEEVREDEA

AXIN1

831

O15169
FETADCEENIESQDR

DPP8

31

Q6V1X1
DAALFDEFVRENDCS

CFAP100

196

Q494V2
VACTAAAIDTAVEEE

KIF4B

481

Q2VIQ3
CEVSEEEFREGFDSD

ELP5

61

Q8TE02
ELDTFSECVREAIQE

DRC3

301

Q9H069
VEFADEVRLSFICTE

FERMT2

626

Q96AC1
ERTEEGCAVAAFSAD

FAM30A

26

Q9NZY2
AEREQRSFCSTVADE

GRIK3

851

Q13003
SDKRIACDEEFSDSE

HDAC2

411

Q92769
VAVCTADFFRDEAER

DPEP1

11

P16444
TDERTCQDIDECSFE

SCUBE1

316

Q8IWY4
DRIAECSSQLAEEEE

MYH10

1006

P35580
VQEFCKAEEVDEDSV

KIF23

201

Q02241
DVIRNAFACFDEEAT

MYL12B

101

O14950
SCEFAVEQVDLDVVE

MUC3B

921

Q9H195
VTSCFRDEDDINDVT

TAF4B

606

Q92750
GLFQDRTCEIVEDTE

STK40

111

Q8N2I9
CTVELVEAAEEFAFA

PHETA1

66

Q8N4B1
LTCSVEDADDNVSFR

SLAMF6

151

Q96DU3
VAADCCETTFIEDRS

SYNDIG1

106

Q9H7V2
TSSEECVTVIFDAED

NCKAP5

661

O14513
IAEDDDDVFVASRTT

NHSL2

1096

Q5HYW2
IVNDSRESCVEENDD

MDM2

366

Q00987
TPDTSFERDVVCEDE

PRC1

191

O43663
RAASFDVCESVDEAG

RHOBTB2

341

Q9BYZ6
VGFCTEVEEDLIDAV

PYCR2

156

Q96C36
EFVERSSCRADTSAE

PPP1R26

466

Q5T8A7
VSDDFEEVVCIGSVA

IARS1

471

P41252
ERAVESDCYAEQVVA

SEMA4C

241

Q9C0C4
NAEAAEEIVDCITES

U2SURP

566

O15042
VDAVEDASSIVFLCD

B4GALNT4

901

Q76KP1
DEEFDVVVCDQVSAC

ALG2

106

Q9H553
EDVIDAANCSSADRF

CIP2A

371

Q8TCG1
FDFDLECETVDQAVE

CLUH

906

O75153
DICESDFDQDQVIDR

THBS4

701

P35443
CEATGADVEEVATAI

UGDH

241

O60701
EDVDAAFTDTDCVVR

USP19

141

O94966
AVCFDVDSTVIREEG

PSPH

16

P78330
FIDTCTGFSAEEEEE

TP53INP1

36

Q96A56
VFLEVDADNCEEVVR

TXNDC2

501

Q86VQ3
ASDSEEEVCDERTSL

PSEN2

6

P49810
CFNETSEIRFEIEDV

SCN8A

1356

Q9UQD0
QVEEAVADFDECIRL

TOMM70

416

O94826
EEVRERFVCDSAFEQ

PRPF40B

651

Q6NWY9
EVERELCSATAEFED

PSME4

531

Q14997
RFEEDSLCSFISEAE

ZSWIM8

21

A7E2V4
IRCVEVSDDQDTGDT

UBE3B

996

Q7Z3V4
VSEEVLVADCASEAV

ZFX

176

P17010
LERECVEETCSYEEA

F2

56

P00734
EAAAVRDISEASVFD

RPS26

46

P62854
VLCAADSVEVETEEE

ZNF407

1141

Q9C0G0
DSLEESRAFCETLEE

SNX16

221

P57768
IRLSEAACEDEDSAS

TTC4

231

O95801
SFNCEVRDEFEELDS

PJA2

221

O43164
ACTDESLAVEERIEA

ZFC3H1

1586

O60293
RRAVSEGCASEDEVE

TBC1D2

911

Q9BYX2
ACEVSVSFEDVTVDF

ZNF81

16

P51508
EDVQCSDILEEADVS

ZFY

76

P08048
FESDEIVAVCAAIAE

TTC33

206

Q6PID6
VDAATTFEELCEEVR

PRKCZ

31

Q05513