Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR3	4.45e-05	4	55	2	GO:0005219
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR3	1.11e-04	6	55	2	GO:0048763
GeneOntologyMolecularFunction	ribonucleoprotein complex binding	GUF1 EEF2 XPO5 IGHMBP2 NEMF	2.55e-04	206	55	5	GO:0043021
GeneOntologyMolecularFunction	ribosome binding	GUF1 EEF2 IGHMBP2 NEMF	3.34e-04	120	55	4	GO:0043022
GeneOntologyMolecularFunction	metallochaperone activity	NUBPL TF	1.11e-03	18	55	2	GO:0016530
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR1 RYR3	1.11e-03	18	55	2	GO:0015278
GeneOntologyMolecularFunction	monoatomic anion:sodium symporter activity	SLC6A11 SLC13A1	1.24e-03	19	55	2	GO:0015373
GeneOntologyMolecularFunction	protease binding	CFLAR LONP2 KIT RYR1	1.55e-03	181	55	4	GO:0002020
GeneOntologyMolecularFunction	tRNA binding	XPO5 IGHMBP2 NEMF	1.78e-03	87	55	3	GO:0000049
GeneOntologyMolecularFunction	phosphatidylinositol kinase activity	ATM PIPSL	2.32e-03	26	55	2	GO:0052742
GeneOntologyMolecularFunction	monoatomic anion:monoatomic cation symporter activity	SLC6A11 SLC13A1	2.32e-03	26	55	2	GO:0015296
HumanPheno	Dermatographic urticaria	SERPING1 ADGRE2 KIT	3.67e-05	14	25	3	HP:0011971
HumanPheno	Physical urticaria	SERPING1 ADGRE2 KIT	4.57e-05	15	25	3	HP:0410134
Domain	Ryanrecept_TM4-6	RYR1 RYR3	2.46e-05	3	54	2	IPR009460
Domain	RyR	RYR1 RYR3	2.46e-05	3	54	2	PF02026
Domain	Ryanodine_rcpt	RYR1 RYR3	2.46e-05	3	54	2	IPR003032
Domain	RR_TM4-6	RYR1 RYR3	2.46e-05	3	54	2	PF06459
Domain	Ryan_recept	RYR1 RYR3	2.46e-05	3	54	2	IPR013333
Domain	RIH_assoc	RYR1 RYR3	1.22e-04	6	54	2	PF08454
Domain	RIH_assoc-dom	RYR1 RYR3	1.22e-04	6	54	2	IPR013662
Domain	EFG_III-V	GUF1 EEF2	1.22e-04	6	54	2	IPR009022
Domain	RIH_dom	RYR1 RYR3	1.22e-04	6	54	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR3	1.22e-04	6	54	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR3	1.22e-04	6	54	2	IPR015925
Domain	EFG_C	GUF1 EEF2	1.22e-04	6	54	2	SM00838
Domain	EFG_C	GUF1 EEF2	1.22e-04	6	54	2	PF00679
Domain	-	RYR1 RYR3	1.22e-04	6	54	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR3	1.22e-04	6	54	2	PF01365
Domain	Ins145_P3_rec	RYR1 RYR3	1.22e-04	6	54	2	PF08709
Domain	-	GUF1 EEF2	1.71e-04	7	54	2	3.30.70.240
Domain	EFG_V	GUF1 EEF2	1.71e-04	7	54	2	IPR000640
Domain	G_TR_CS	GUF1 EEF2	2.92e-04	9	54	2	IPR031157
Domain	MIR	RYR1 RYR3	3.64e-04	10	54	2	PS50919
Domain	MIR	RYR1 RYR3	3.64e-04	10	54	2	PF02815
Domain	MIR	RYR1 RYR3	3.64e-04	10	54	2	SM00472
Domain	MIR_motif	RYR1 RYR3	3.64e-04	10	54	2	IPR016093
Domain	G_TR_1	GUF1 EEF2	6.27e-04	13	54	2	PS00301
Domain	ANX	ANXA6 ANXA10	6.27e-04	13	54	2	SM00335
Domain	ANNEXIN	ANXA6 ANXA10	6.27e-04	13	54	2	PS00223
Domain	Annexin_repeat_CS	ANXA6 ANXA10	6.27e-04	13	54	2	IPR018252
Domain	Annexin	ANXA6 ANXA10	6.27e-04	13	54	2	PF00191
Domain	Annexin_repeat	ANXA6 ANXA10	6.27e-04	13	54	2	IPR018502
Domain	-	ANXA6 ANXA10	6.27e-04	13	54	2	1.10.220.10
Domain	Annexin	ANXA6 ANXA10	7.30e-04	14	54	2	IPR001464
Domain	EFTu-like_2	GUF1 EEF2	1.22e-03	18	54	2	IPR004161
Domain	GTP_EFTU_D2	GUF1 EEF2	1.22e-03	18	54	2	PF03144
Domain	G_TR_2	GUF1 EEF2	1.22e-03	18	54	2	PS51722
Domain	TF_GTP-bd_dom	GUF1 EEF2	1.36e-03	19	54	2	IPR000795
Domain	-	EEF2 LONP2	1.66e-03	21	54	2	3.30.230.10
Domain	Ribosomal_S5_D2-typ_fold_subgr	EEF2 LONP2	1.83e-03	22	54	2	IPR014721
Domain	Transl_B-barrel	GUF1 EEF2	2.75e-03	27	54	2	IPR009000
Domain	Ribosomal_S5_D2-typ_fold	EEF2 LONP2	4.34e-03	34	54	2	IPR020568
Domain	EF-hand_8	KCNIP4 RYR1	4.34e-03	34	54	2	PF13833
Domain	Serpin_dom	SERPING1 SERPINA10	4.85e-03	36	54	2	IPR023796
Domain	SERPIN	SERPING1 SERPINA10	5.12e-03	37	54	2	SM00093
Domain	SERPIN	SERPING1 SERPINA10	5.12e-03	37	54	2	PS00284
Domain	Serpin	SERPING1 SERPINA10	5.40e-03	38	54	2	PF00079
Domain	Serpin_fam	SERPING1 SERPINA10	5.68e-03	39	54	2	IPR000215
Pubmed	Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.	MUSK RYR1 RYR3	7.46e-08	6	55	3	26025922
Pubmed	Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.	MUSK RYR1 RYR3	2.08e-07	8	55	3	21441923
Pubmed	Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.	RYR1 RYR3	2.46e-06	2	55	2	9489997
Pubmed	The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.	RYR1 RYR3	2.46e-06	2	55	2	12640042
Pubmed	Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.	RYR1 RYR3	2.46e-06	2	55	2	14592949
Pubmed	Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.	RYR1 RYR3	2.46e-06	2	55	2	9799464
Pubmed	Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.	RYR1 RYR3	2.46e-06	2	55	2	17118445
Pubmed	RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.	RYR1 RYR3	2.46e-06	2	55	2	11500519
Pubmed	Distinct tissue site-specific requirements of mast cells and complement components C3/C5a receptor in IgG immune complex-induced injury of skin and lung.	C3 KIT	2.46e-06	2	55	2	11441111
Pubmed	ATM mediated phosphorylation of CHD4 contributes to genome maintenance.	CHD4 ATM	2.46e-06	2	55	2	21219611
Pubmed	Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.	RYR1 RYR3	2.46e-06	2	55	2	12565913
Pubmed	Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.	RYR1 RYR3	2.46e-06	2	55	2	9192302
Pubmed	Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.	RYR1 RYR3	2.46e-06	2	55	2	7556644
Pubmed	Expression of cyclin D2, P53, Rb and ATM cell cycle genes in brain tumors.	ATM CCND2	2.46e-06	2	55	2	20077038
Pubmed	Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.	RYR1 RYR3	2.46e-06	2	55	2	15894801
Pubmed	Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.	RYR1 RYR3	2.46e-06	2	55	2	9817784
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	ENOSF1 BABAM1 B3GNT5 PEX3 GPT C3 CHD4 RPGR NUBPL RYR1 CAP1	4.78e-06	1293	55	11	15342556
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR3	7.36e-06	3	55	2	18403125
Pubmed	Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.	RYR1 RYR3	7.36e-06	3	55	2	11171121
Pubmed	TLR4 Receptor Induces 2-AG-Dependent Tolerance to Lipopolysaccharide and Trafficking of CB2 Receptor in Mast Cells.	KIT CNR2	7.36e-06	3	55	2	30814309
Pubmed	The effect of C1 inhibitor on intestinal ischemia and reperfusion injury.	SERPING1 C3	7.36e-06	3	55	2	18787060
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR3	7.36e-06	3	55	2	7876312
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR3	7.36e-06	3	55	2	22948152
Pubmed	MAPK kinase 3 specifically regulates Fc epsilonRI-mediated IL-4 production by mast cells.	MAP2K3 KIT	7.36e-06	3	55	2	21841136
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR3	7.36e-06	3	55	2	10788707
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR3	7.36e-06	3	55	2	7621815
Pubmed	ATM kinase activity modulates Fas sensitivity through the regulation of FLIP in lymphoid cells.	CFLAR ATM	7.36e-06	3	55	2	17932249
Pubmed	Effect of interferon-gamma on complement gene expression in different cell types.	SERPING1 C3	7.36e-06	3	55	2	1531292
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR3	7.36e-06	3	55	2	10473538
Pubmed	Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.	RYR1 RYR3	7.36e-06	3	55	2	18313230
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR3	7.36e-06	3	55	2	18434746
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR3	7.36e-06	3	55	2	9204703
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR3	7.36e-06	3	55	2	21881589
Pubmed	Cannabinoid receptor 2 undergoes Rab5-mediated internalization and recycles via a Rab11-dependent pathway.	RAB11FIP1 CNR2	7.36e-06	3	55	2	21640764
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR3	7.36e-06	3	55	2	12213830
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR3	7.36e-06	3	55	2	9242641
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR3	7.36e-06	3	55	2	25239916
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR3	7.36e-06	3	55	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR3	7.36e-06	3	55	2	11159936
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR3	7.36e-06	3	55	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR3	7.36e-06	3	55	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR3	7.36e-06	3	55	2	7635066
Pubmed	Distinct patterns of expression of the D-type cyclins during testicular development in the mouse.	KIT CCND2	1.47e-05	4	55	2	7537638
Pubmed	Characterization of the binding sites for the interactions between FKBP12 and intracellular calcium release channels.	RYR1 RYR3	1.47e-05	4	55	2	22100703
Pubmed	Determination of a gene and environment risk model for age-related macular degeneration.	SERPING1 C3	1.47e-05	4	55	2	20576771
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR3	1.47e-05	4	55	2	23413940
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR3	1.47e-05	4	55	2	9607712
Pubmed	Mast cell-expressed complement receptor, not TLR2, is the main detector of zymosan in peritonitis.	C3 KIT	1.47e-05	4	55	2	17154261
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR3	1.47e-05	4	55	2	23482488
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR3	1.47e-05	4	55	2	18206662
Pubmed	Characterization of endocannabinoid-mediated induction of myeloid-derived suppressor cells involving mast cells and MCP-1.	KIT CNR2	1.47e-05	4	55	2	24319288
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR3	1.47e-05	4	55	2	9384575
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR1 RYR3	2.45e-05	5	55	2	23918386
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR1 RYR3	2.45e-05	5	55	2	19011160
Pubmed	Membrane depolarization causes a direct activation of G protein-coupled receptors leading to local Ca2+ release in smooth muscle.	RYR1 RYR3	3.67e-05	6	55	2	19549818
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR1 RYR3	3.67e-05	6	55	2	23463619
Pubmed	FKBP12.6 and cADPR regulation of Ca2+ release in smooth muscle cells.	RYR1 RYR3	3.67e-05	6	55	2	14592808
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR1 RYR3	3.67e-05	6	55	2	25966694
Pubmed	HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.	RYR1 RYR3	3.67e-05	6	55	2	19009018
Pubmed	Mast cells have a pivotal role in TNF-independent lymph node hypertrophy and the mobilization of Langerhans cells in response to bacterial peptidoglycan.	C3 KIT	3.67e-05	6	55	2	16849485
Pubmed	Phenotype and allele frequencies of some serum protein polymorphisms in populations of the Balkans.	C3 TF	3.67e-05	6	55	2	15648851
Pubmed	Type 3 and type 1 ryanodine receptors are localized in triads of the same mammalian skeletal muscle fibers.	RYR1 RYR3	3.67e-05	6	55	2	10444070
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR1 RYR3	3.67e-05	6	55	2	20519450
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR1 RYR3	3.67e-05	6	55	2	16844763
Pubmed	Mapping Extracellular Protein-Protein Interactions Using Extracellular Proximity Labeling (ePL).	EEF2 C3 TF HDGFL2 CAP1	4.52e-05	247	55	5	39238192
Pubmed	Extracellular Hsp90α and clusterin synergistically promote breast cancer epithelial-to-mesenchymal transition and metastasis via LRP1.	SERPING1 C3 TF	4.73e-05	44	55	3	31273033
Pubmed	Critical role of macrophages and their activation via MyD88-NFκB signaling in lung innate immunity to Mycoplasma pneumoniae.	C3 KIT	5.13e-05	7	55	2	21203444
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR1 RYR3	5.13e-05	7	55	2	11860456
Pubmed	C1q governs deposition of circulating immune complexes and leukocyte Fcgamma receptors mediate subsequent neutrophil recruitment.	C3 KIT	5.13e-05	7	55	2	15466618
Pubmed	Human immunodeficiency virus-1 Tat activates calpain proteases via the ryanodine receptor to enhance surface dopamine transporter levels and increase transporter-specific uptake and Vmax.	RYR1 RYR3	5.13e-05	7	55	2	20962236
Pubmed	Eukaryotic elongation factor 2 controls TNF-α translation in LPS-induced hepatitis.	EEF2 MAP2K3	5.13e-05	7	55	2	23202732
Pubmed	Calcium Influx and Release Cooperatively Regulate AChR Patterning and Motor Axon Outgrowth during Neuromuscular Junction Formation.	MUSK RYR1	5.13e-05	7	55	2	29949772
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	SERPING1 C3 SERPINA10 KIT TF	5.45e-05	257	55	5	16335952
Pubmed	Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.	SERPING1 C3 TF	5.78e-05	47	55	3	14760718
Pubmed	[The use of discrete characters in discriminant analysis for diagnosis of pulmonary tuberculosis and for classification of patients differing in treatment efficiency based on polymorphisms at nine codominant loci-HP, GC, TF, PI, PGM1, GLO1, C3, ACP1 and ESD].	C3 TF	6.83e-05	8	55	2	12942785
Pubmed	ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.	RYR1 RYR3	6.83e-05	8	55	2	30563862
Pubmed	Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.	RYR1 RYR3	6.83e-05	8	55	2	11784029
Pubmed	[Analysis of heterozygosity levels at P1,TF, PGM1, ACP1, HP, GC, GLO, C3, and ESD loci in pulmonary tuberculosis patients with different treatment outcomes].	C3 TF	6.83e-05	8	55	2	11785295
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR1 RYR3	6.83e-05	8	55	2	19033399
Pubmed	Mutational profiling of kinases in human tumours of pancreatic origin identifies candidate cancer genes in ductal and ampulla of vater carcinomas.	ATM KIT	8.78e-05	9	55	2	20838624
Pubmed	Increased muscle stress-sensitivity induced by selenoprotein N inactivation in mouse: a mammalian model for SEPN1-related myopathy.	RYR1 RYR3	8.78e-05	9	55	2	21858002
Pubmed	Isolation and chromosomal location of Nsk1, a novel murine putative receptor tyrosine kinase.	KIT MUSK	1.10e-04	10	55	2	8535092
Pubmed	Association of genetic polymorphisms with hepatotoxicity in patients with childhood acute lymphoblastic leukemia or lymphoma.	SLC13A1 KCNIP4	1.10e-04	10	55	2	20670164
Pubmed	Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides.	SERPING1 SERPINA10 TF	1.14e-04	59	55	3	17330941
Pubmed	Seventy-five genetic loci influencing the human red blood cell.	PRKAG2 KIT CCND2	1.32e-04	62	55	3	23222517
Pubmed	New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.	RYR1 RYR3	1.60e-04	12	55	2	19095005
Pubmed	Evaluation of candidate stromal epithelial cross-talk genes identifies association between risk of serous ovarian cancer and TERT, a cancer susceptibility "hot-spot".	CFLAR SERPING1 C3 CCND2	1.62e-04	172	55	4	20628624
Pubmed	Particularities of the vasculature can promote the organ specificity of autoimmune attack.	C3 KIT	1.89e-04	13	55	2	16444258
Pubmed	Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects.	ATM MAP2K3	1.89e-04	13	55	2	18722365
Pubmed	Identification and analysis of genes from the mouse otic vesicle and their association with developmental subprocesses through in situ hybridization.	ZNF462 XPO5 CCND2	2.24e-04	74	55	3	15031102
Pubmed	Activity-dependent neuroprotective protein recruits HP1 and CHD4 to control lineage-specifying genes.	ZNF462 EEF2 CHD4	2.24e-04	74	55	3	29795351
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	GUF1 XPO5 ANXA6 NEMF ATM ARHGEF2 NUBPL CAP1	2.49e-04	1061	55	8	33845483
Pubmed	In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.	UBE2NL EEF2 ANXA6 SERPING1 C3 SERPINA10 TF CAP1	2.64e-04	1070	55	8	23533145
Pubmed	Gene expression analysis of the embryonic subplate.	CFLAR KIT CSPP1 CCND2	2.66e-04	196	55	4	21862448
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MRM3 UBE2NL EEF2 ANXA6 NEMF CHD4 ARHGEF2 PIPSL NUBPL	2.77e-04	1371	55	9	36244648
Pubmed	Functions of c-Jun in liver and heart development.	TF CCND2	2.90e-04	16	55	2	10352021
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	BABAM1 XPO5 CHD4 ATM ARHGEF2 MAP2K3	3.09e-04	582	55	6	20467437
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	EEF2 NEMF C3 CHD4 ARHGEF2 HDGFL2	3.67e-04	601	55	6	33658012
Pubmed	Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm.	EEF2 XPO5	3.70e-04	18	55	2	12426392
Pubmed	Comparative proteomic analysis of intra- and interindividual variation in human cerebrospinal fluid.	C3 TF	3.70e-04	18	55	2	16199891
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR3	1.22e-05	3	37	2	287
GeneFamily	Annexins\|Endogenous ligands	ANXA6 ANXA10	3.13e-04	13	37	2	404
GeneFamily	Beta 3-glycosyltransferases	B3GNT5 CHSY3	1.09e-03	24	37	2	426
GeneFamily	Serpin peptidase inhibitors	SERPING1 SERPINA10	2.59e-03	37	37	2	739
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	KIT MUSK	3.03e-03	40	37	2	321
ToppCell	COVID-19-APC-like-Monocytes\|COVID-19 / group, cell type (main and fine annotations)	KCNIP4 NLGN2 MUSK RYR1	4.34e-05	158	55	4	a0d94bd067424783863a48db20976d4c2043600c
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT SERPING1 C3 SERPINA10	4.56e-05	160	55	4	8de1fc75241d9bf2b355afa0e9ef39fea1977177
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IGHMBP2 ADGRE2 KIT RYR1	4.56e-05	160	55	4	fe9970c160159b35f6599ed13c89cfb49264d554
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C3 ADGRE2 RYR1 CCND2	4.56e-05	160	55	4	1f7acdc8b08152d5817fc53bbf47b4a22d9c91b5
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT SERPING1 C3 SERPINA10	4.90e-05	163	55	4	03d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT SERPING1 C3 SERPINA10	4.90e-05	163	55	4	1c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCell	droplet-Liver-Hepatocytes-18m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT SERPING1 C3 SERPINA10	4.90e-05	163	55	4	7e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCell	3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKNA ADGRE2 KIT RYR3	5.91e-05	171	55	4	5885e69e997cc2f6a27afebfe57001ca0ac062a6
ToppCell	normal-na-Hematopoietic-Progen-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ENOSF1 EEF2 NLGN2 ATM	6.18e-05	173	55	4	e666364eb110c1c976e5b09a632dd1454513f131
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_C\|356C / Donor, Lineage, Cell class and subclass (all cells)	ANXA6 AKNA ATM CCND2	6.90e-05	178	55	4	7203149864cc8d5ae25329fdbf15c6b73c3d3595
ToppCell	COPD-Myeloid-Mast\|World / Disease state, Lineage and Cell class	ZNF462 ADGRE2 KIT RYR3	7.52e-05	182	55	4	68a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	7.68e-05	183	55	4	5472cdce6d99314d229418412acf1fff6340db7d
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	7.85e-05	184	55	4	5939527d24d299e562e707469c9123890edd76be
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	7.85e-05	184	55	4	a2191dd5546efd357b23e625beb3c5820476f243
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 AKNA ADGRE2	7.85e-05	184	55	4	b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCell	facs-Marrow-T-cells-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 AKNA ADGRE2	8.01e-05	185	55	4	e1fd0a807def8c2127194108b1a30c6de7024292
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.01e-05	185	55	4	1d731d69d8db8aef4a11439b8abd1030c7e6ac4c
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.01e-05	185	55	4	b8d02c9426740ffcb69d2e6f95473b388149d297
ToppCell	COPD-Myeloid-Mast\|COPD / Disease state, Lineage and Cell class	ZNF462 ADGRE2 KIT RYR3	8.18e-05	186	55	4	def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.18e-05	186	55	4	90eaf6ffb4ce0c34fa1e79f0c8f36f217f44973b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.18e-05	186	55	4	bd8a9753df219084e19e7f94447856e86608325c
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.35e-05	187	55	4	f0de86ef25e344d9b1860ee26308877d6c25ed31
ToppCell	droplet-Large_Intestine-COLON:P+D-30m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 NXPE2 ADGRE2 CCND2	8.35e-05	187	55	4	a63fa3255ad58f3a73c596df99ce9649fdbaeb39
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.35e-05	187	55	4	b71d0cd91bc98e020757c1d071a13ad48d718bcf
ToppCell	droplet-Large_Intestine-COLON:P+D\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B3GNT5 NXPE2 ADGRE2 CCND2	8.35e-05	187	55	4	b1bb5c48258a9d058614d23001899dbe44857a1f
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA6 SERPING1 C3 MUSK	8.35e-05	187	55	4	f0c4d93f75615e570e4465fd622e3124189618a1
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANXA6 SERPING1 C3 MUSK	8.35e-05	187	55	4	3ff57da09ed8394913fb683669d7bff84a936623
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.52e-05	188	55	4	14072d0b82df55711d5356b2209f4f0bdd90dc27
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.52e-05	188	55	4	60242c29c7f16c94a84685d3bc4ed93a66e70152
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 NEMF CHD4 CCND2	8.52e-05	188	55	4	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.52e-05	188	55	4	b04fd6a724c117eb9a979c29b91f90113feb7a5c
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.70e-05	189	55	4	70eea8c94fa56bb15bee8065de47acea156794e9
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-Oligodendrocyte-Oligo_L4-6_OPALIN\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ENOSF1 FA2H TF MUSK	8.70e-05	189	55	4	b60c8a29d3169c4830fe63b01db90c57660fc239
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZNF462 EEF2 ANXA6 CCND2	8.88e-05	190	55	4	1634a6044dce4e026a63976031a498c7460e3dce
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-T4_em-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	ZNF462 EEF2 ANXA6 CCND2	8.88e-05	190	55	4	08813c2f9321b82f0ec66854bb7a383aa1171780
ToppCell	facs-Pancreas-Endocrine-3m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP SERPING1 SERPINA10 CCND2	9.06e-05	191	55	4	b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP SERPING1 SERPINA10 CCND2	9.06e-05	191	55	4	657297cd19d05a7e7bb74fc3a086fbd95f47aae4
ToppCell	NS-moderate-d_16-33-Lymphoid-Treg\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA6 AKNA ATM CCND2	9.25e-05	192	55	4	48d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCell	Enterocyte_Progenitors-C_06\|Enterocyte_Progenitors / shred on cell type and cluster	ANXA10 SERPING1 KCNIP4 C3	9.25e-05	192	55	4	b9938e1a929c00628cc6ebfdf10cf285167f445c
ToppCell	NS-moderate-d_07-13-Lymphoid\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ANXA6 AKNA ATM CCND2	9.25e-05	192	55	4	bd4059bfc2159f5ed8bbb2a5408b56117ca6f8e1
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	SERPING1 KCNIP4 C3 CCND2	9.43e-05	193	55	4	ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell	C_06\|World / shred on cell type and cluster	ANXA10 SERPING1 KCNIP4 C3	9.62e-05	194	55	4	5cb42e09f380c4468cdc603ec0c3de35eadd3213
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 SERPING1 MUSK	9.82e-05	195	55	4	4d63e0dca30ae57960459d2fbcba09122273e37b
ToppCell	PBMC-Control-cDC_11\|Control / Compartment, Disease Groups and Clusters	ZNF462 NUBPL KIT CNR2	9.82e-05	195	55	4	74d560ff0f47512441c305885c5c16272f711b8e
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ADGRE2 KIT RYR3 CCND2	9.82e-05	195	55	4	f1f48e2e57b2282572959b152aad4bee05143f03
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 SERPING1 MUSK	9.82e-05	195	55	4	661af601a3561fe3aacf2444ad7b8927fa88b48a
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 SERPING1 MAP2K3	1.00e-04	196	55	4	66d76249bd2770cdddff2c1fe59a016e95da2124
ToppCell	COVID-19_Mild-Classical_Monocyte-cMono_4\|COVID-19_Mild / Disease condition and Cell class	SERPING1 RAB11FIP1 PRKAG2 ADGRE2	1.00e-04	196	55	4	3729d1444c65cad640377894decc64129bc3fd5b
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ADGRE2 CNR2 RYR3 CCND2	1.00e-04	196	55	4	5bb8653af62334ded8aad48b24b64d7b54bc3cd5
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 SERPING1 MAP2K3	1.00e-04	196	55	4	9bd4c146fc7555e32adfa393b3a07846eb826d25
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 MAP2K3 MUSK	1.00e-04	196	55	4	97ac47daf5bb07fa5dda3976e1ae402750f959b5
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	EEF2 AKNA KIT CAP1	1.00e-04	196	55	4	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EEF2 ANXA6 MAP2K3 MUSK	1.02e-04	197	55	4	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	Monocytes-cDCs\|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis	ANXA6 AKNA RAB11FIP1 KIT	1.02e-04	197	55	4	15cb9fe1c3bab80bd24728fd9ac7ba385912ac33
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANXA6 AKNA ATM CCND2	1.04e-04	198	55	4	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	10x5'v1-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	ADGRE2 KIT RYR3 CCND2	1.04e-04	198	55	4	2e6630eab77b12a6059682ab5ba465f38e469102
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANXA6 AKNA ATM CCND2	1.04e-04	198	55	4	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	T/NK_cells-CD8+_Naive_T_cell\|T/NK_cells / Lineage and Cell class	CFLAR ANXA6 AKNA CAP1	1.04e-04	198	55	4	5b78118af2283f2e1ad9c6a6ab448a018bf2f2e0
ToppCell	distal-2-Hematologic-Natural_Killer_T\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ANXA6 AKNA CNR2 CCND2	1.06e-04	199	55	4	f89165dab4a75ef5d93bf0f047fc61099442db35
ToppCell	healthy_donor-Lymphocytic\|healthy_donor / Disease condition, Lineage, Cell class and subclass	ANXA6 AKNA ATM CCND2	1.06e-04	199	55	4	2841e16d54acd344ba454f024e285c28abc37319
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CFLAR RAB11FIP1 MAP2K3 CAP1	1.06e-04	199	55	4	b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCell	Sigmoid-Dendritic_cell-cDC1\|Dendritic_cell / Region, Cell class and subclass	GUF1 ADHFE1 XPO5 NUBPL	1.08e-04	200	55	4	09deb831fc2c8a8867cc850f3aa094a5e48489ff
ToppCell	Parenchymal-10x5prime-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ANXA6 ATM CNR2 CCND2	1.08e-04	200	55	4	b76f000582b38f4c61b44081eba9ae213382cb6f
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	1.38e-04	81	55	3	f7f2adf1fecd34b444de92d4c1bf45eb0281f4ad
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Thalamus / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	1.38e-04	81	55	3	8d323402ee5fb450947b00b0d75ca8f07aa4769e
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Thalamus / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	1.38e-04	81	55	3	55cbf579d93e14bc4aebbed0fd11076c9313cdac
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	1.54e-04	84	55	3	f7ce09c6fb2795b7aecabce00cb9830b3c1a7d0e
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	1.54e-04	84	55	3	5d5e519a6652029b9f5275c8e648bbb123fd07b9
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	1.54e-04	84	55	3	2b477de422a9f6a8474cba05094577b88236a4f0
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	2.14e-04	94	55	3	858dda192747e71533736247bc9e135f763a8860
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	2.14e-04	94	55	3	901c4908d27a06c81853a02042cd331549e0e27d
ToppCell	Striatum-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-\|Striatum / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	2.14e-04	94	55	3	9d1dfd534871da30bc25a42e36bed9826f6127d8
ToppCell	Thalamus-Endothelial-ENDOTHELIAL_STALK-Flt1_1\|Thalamus / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	3.31e-04	109	55	3	4e4a884b8979f4ff8b232c1581ea78884dda29ed
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuronal-Interneuron\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ENOSF1 ANXA6 RYR1	4.49e-04	121	55	3	b2d571f571133c281d72584fe925cebbd2317829
ToppCell	Endothelial-Endothelial-F\|Endothelial / shred on cell class and cell subclass (v4)	CFLAR SERPING1 KIT	4.60e-04	122	55	3	2cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	ANXA6 PRKAG2 CSPP1	4.94e-04	125	55	3	43aa4b77dccf0ea2979218826af16034f2017c3a
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	6.73e-04	139	55	3	34398a6f21a1e670497655a7bb7f3cde9e117560
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_STALK-Flt1_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	6.73e-04	139	55	3	450c4152c9fe4ec503271bb3cf93739918c59509
ToppCell	Posterior_cortex-Endothelial-ENDOTHELIAL_STALK\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TBX4 NXPE2 RAB11FIP1	7.31e-04	143	55	3	35d3652680c4dddd293301595d813161c66e5673
ToppCell	Children_(3_yrs)-Immune-mast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGRE2 KIT RYR3	7.76e-04	146	55	3	f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCell	lung-Type_II_Pneumocytes\|lung / shred on tissue and cell subclass	EEF2 SERPING1 C3	7.92e-04	147	55	3	8a3039de45b8087f8319e2e37329acf7278219b7
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Mucinous-3\|TCGA-Stomach / Sample_Type by Project: Shred V9	SLC13A1 CHSY3 NXPE2	8.07e-04	148	55	3	c95a732163050cfb5d604c2a4c9eb1afa9f19a95
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FA2H KCNIP4 KIT	8.23e-04	149	55	3	cc911b454fe4e4b489885b9920baa7eb01a027ba
ToppCell	droplet-Fat-Scat-21m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB11FIP1 ADGRE2 RYR1	8.39e-04	150	55	3	b6e5e04aaf1c5265ac07581868d3159f9292a84c
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4_activated\|Lung / Manually curated celltypes from each tissue	XPO5 NLGN2 NUBPL	8.55e-04	151	55	3	9bfb807e1180b31fa9a2c500ce993de9707c070f
ToppCell	Children_(3_yrs)-Immune-mast_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGRE2 KIT RYR3	8.55e-04	151	55	3	bbf735c6433c3fc2feedb24ed6f48c51d545fb60
ToppCell	droplet-Liver-Hepatocytes-24m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT SERPING1 C3	8.72e-04	152	55	3	c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCell	facs-Brain_Myeloid-Cortex-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C3 ADGRE2 CCND2	8.89e-04	153	55	3	0ef7c45cdd854c79e527006034029767f8e108b2
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANXA10 ADGRE2 CCND2	9.06e-04	154	55	3	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	facs-Brain_Myeloid-Cortex_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE2 RYR1 CCND2	9.40e-04	156	55	3	2ba838bc864c2c1767bcab7bb4d790af96b91387
ToppCell	3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	KIT TF UBFD1	9.57e-04	157	55	3	eb2520c237543ea4869d4386afc0457b111f6193
ToppCell	Children_(3_yrs)-Immune-mast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ADGRE2 KIT RYR3	9.57e-04	157	55	3	ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE2 KIT CCND2	9.75e-04	158	55	3	f41ee21e5888359d817be1e3a902c132cb68e350
ToppCell	facs-Brain_Myeloid-Cerebellum-24m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE2 KIT CCND2	9.75e-04	158	55	3	d689feb7f612aef170da76fcf14abf2dd589082b
ToppCell	facs-Brain_Myeloid-Cerebellum-24m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRE2 KIT CCND2	9.75e-04	158	55	3	829ff3df46f173f2ff1c435e9bce35425e603b42
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAB11FIP1 ADGRE2 CCND2	9.93e-04	159	55	3	323cb4a2416d2e6bff0a3f225d2edeae9ab7dc76
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	C3 ADGRE2 MAP2K3	9.93e-04	159	55	3	2f6c60ddff2208a68146f9786143d9aefd528840
ToppCell	BAL-Mild-Myeloid-cDC-cDC-cDC_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	C3 ADGRE2 MAP2K3	9.93e-04	159	55	3	ded4e3626a62fb6334403b7213b467fb7e8131c3
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	SLC6A11 TBX4 RYR3	1.01e-03	160	55	3	d783d29150033e9181c0e30870070268fed3fd85
ToppCell	droplet-Liver-Hepatocytes-18m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPT SERPING1 C3	1.03e-03	161	55	3	274838cebdc7af1db32d309dfe42ef7ccd3c190b
Drug	oxalate	ADHFE1 SLC13A1 GPT TF RYR1 RYR3	1.99e-06	158	54	6	CID000000971
Drug	prostaglandin E2; Up 200; 10uM; PC3; HT_HG-U133A	CFLAR PEX3 ANXA10 CHD4 ATM CNR2	4.66e-06	183	54	6	6547_UP
Drug	GSK-3beta Inhibitor VIII; Down 200; 10uM; PC3; HT_HG-U133A	ENOSF1 CFLAR LONP2 C3 RPGR CSPP1	5.44e-06	188	54	6	7097_DN
Drug	Basic Violet 11:1	CFLAR ATM	5.52e-06	2	54	2	CID000062265
Drug	5'-adenylyl (beta,gamma-methylene)diphosphonate	RYR1 RYR3	5.52e-06	2	54	2	ctd:C005147
Drug	TSTU	C3 TF	1.65e-05	3	54	2	CID009857522
Drug	2-hydroxycarbazole	RYR1 RYR3	1.65e-05	3	54	2	CID000093551
Drug	carboxyprimaquine	ADHFE1 C3	1.65e-05	3	54	2	CID000127542
Drug	1,1'-diheptyl-4,4'-bipyridinium	RYR1 RYR3	1.65e-05	3	54	2	CID000080262
Drug	cis-diammineplatinum(II	RYR1 RYR3	1.65e-05	3	54	2	CID000159790
Drug	2-hydroxyheptanoic acid	RYR1 RYR3	1.65e-05	3	54	2	CID002750949
Drug	flubendiamide	RYR1 RYR3	1.65e-05	3	54	2	CID011193251
Drug	Ryanodyl 3-(pyridine-3-carboxylate	RYR1 RYR3	1.65e-05	3	54	2	CID005748312
Drug	8N3-cADPR	RYR1 RYR3	1.65e-05	3	54	2	CID000127713
Drug	aminodantrolene	RYR1 RYR3	1.65e-05	3	54	2	CID009570289
Drug	A-30	RYR1 RYR3	3.30e-05	4	54	2	CID003028528
Drug	PCB74	RYR1 RYR3	3.30e-05	4	54	2	CID000036218
Drug	148504-47-6	RYR1 RYR3	3.30e-05	4	54	2	CID006444275
Drug	Bastadin 10	RYR1 RYR3	3.30e-05	4	54	2	CID009589366
Drug	SC 38249	RYR1 RYR3	3.30e-05	4	54	2	CID000134834
Drug	AC1L1U7A	RYR1 RYR3	3.30e-05	4	54	2	CID000035682
Drug	diad	CFLAR RYR1 RYR3	3.96e-05	28	54	3	CID000075555
Drug	M-HN	KIT RYR1 RYR3	5.41e-05	31	54	3	CID000015450
Drug	6-methoxy-8-aminoquinoline	ADHFE1 C3	5.50e-05	5	54	2	CID000007023
Drug	troglitazone; Up 200; 10uM; PC3; HT_HG-U133A	FA2H IGHMBP2 C3 ADGRE2 MAP2K3	5.59e-05	173	54	5	1232_UP
Drug	adenosine diphosphoribose	EEF2 ADHFE1 RYR1 RYR3	6.76e-05	92	54	4	CID000030243
Drug	GW 4064	ADHFE1 SLC13A1 FA2H GPT KCNIP4 C3 TF	7.54e-05	438	54	7	ctd:C412815
Drug	MBED	RYR1 RYR3	8.23e-05	6	54	2	CID000129958
Drug	chloro-m-cresol	RYR1 RYR3	8.23e-05	6	54	2	CID000012008
Drug	AC1O528X	RYR1 RYR3	8.23e-05	6	54	2	CID006475857
Drug	2alpha-propoxy-1alpha,25-dihydroxyvitamin D3	C3 RYR1	8.23e-05	6	54	2	CID010062706
Drug	NSC114784	RYR1 RYR3	8.23e-05	6	54	2	CID000419425
Drug	NSC692750	RYR1 RYR3	8.23e-05	6	54	2	CID000078910
Drug	AH23848 hemicalcium salt hydrate; Up 200; 1uM; PC3; HT_HG-U133A	CFLAR ANXA10 CHD4 ATM NUBPL	8.29e-05	188	54	5	6885_UP
Drug	NSC226080	CFLAR EEF2 ATM MAP2K3 KIT TF RYR1 RYR3 CCND2	8.45e-05	782	54	9	CID000005040
Drug	Syrosingopine [84-36-6]; Up 200; 6uM; MCF7; HT_HG-U133A	IGHMBP2 RPGR ARHGEF2 RAB11FIP1 MUSK	9.16e-05	192	54	5	6213_UP
Drug	Noscapine [128-62-1]; Down 200; 9.6uM; MCF7; HT_HG-U133A	CFLAR RPGR ATM MAP2K3 CNR2	9.16e-05	192	54	5	2745_DN
Drug	Idoxuridine [54-42-2]; Up 200; 11.2uM; MCF7; HT_HG-U133A	CFLAR IGHMBP2 C3 RAB11FIP1 CNR2	9.38e-05	193	54	5	1480_UP
Drug	Naltrexone hydrochloride dihydrate [16676-29-2]; Down 200; 9.6uM; HL60; HG-U133A	ENOSF1 CFLAR UBE2NL ANXA6 ATM	9.38e-05	193	54	5	1363_DN
Drug	dihydropyridine	ADHFE1 IGHMBP2 PRKAG2 RYR1 RYR3	9.38e-05	193	54	5	CID000104822
Drug	Metformin hydrochloride [1115-70-4]; Down 200; 24.2uM; HL60; HT_HG-U133A	CFLAR UBE2NL IGHMBP2 C3 ATM	9.61e-05	194	54	5	1858_DN
Drug	Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A	CFLAR PEX3 ATM ARHGEF2 CNR2	9.85e-05	195	54	5	4686_DN
Drug	coproporphyrinogen III	GUF1 C3 TF	1.00e-04	38	54	3	CID000000321
Drug	AC1L98DX	EEF2 RYR1 RYR3	1.00e-04	38	54	3	CID000439957
Drug	Ethosuximide [77-67-8]; Down 200; 28.4uM; MCF7; HT_HG-U133A	CFLAR UBE2NL C3 ARHGEF2 MAP2K3	1.01e-04	196	54	5	2280_DN
Drug	Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	CFLAR CHD4 MAP2K3 CSPP1 CNR2	1.01e-04	196	54	5	1708_DN
Drug	Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A	CFLAR RPGR ATM MAP2K3 CNR2	1.03e-04	197	54	5	6018_DN
Drug	Naloxone hydrochloride [357-08-4]; Down 200; 11uM; MCF7; HT_HG-U133A	CFLAR RPGR ATM MAP2K3 CNR2	1.03e-04	197	54	5	5606_DN
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A	CFLAR ATM ARHGEF2 MAP2K3 CNR2	1.03e-04	197	54	5	6063_DN
Drug	Halcinonide [3093-35-4]; Down 200; 8.8uM; MCF7; HT_HG-U133A	LONP2 IGHMBP2 PEX3 ATM CNR2	1.06e-04	198	54	5	4703_DN
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; HL60; HT_HG-U133A	C3 RPGR ATM ADGRE2 MAP2K3	1.06e-04	198	54	5	1838_DN
Drug	celecoxib; Up 200; 10uM; MCF7; HG-U133A	CFLAR IGHMBP2 ATM CSPP1 TF	1.06e-04	198	54	5	206_UP
Drug	Azumoleno	RYR1 RYR3	1.15e-04	7	54	2	CID000056259
Drug	mag-indo-1	RYR1 RYR3	1.15e-04	7	54	2	CID000131881
Drug	Br2BAPTA	RYR1 RYR3	1.15e-04	7	54	2	CID003081001
Drug	[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate	RYR1 RYR3	1.15e-04	7	54	2	CID009547999
Drug	Hoe 704	ADHFE1 GPT	1.15e-04	7	54	2	CID000119559
Drug	CHEBI:564108	RYR1 RYR3	1.15e-04	7	54	2	CID006400637
Drug	dipyrone	GPT RYR1 RYR3	1.17e-04	40	54	3	CID000003110
Drug	peimine	KIT MUSK	1.53e-04	8	54	2	CID000131900
Drug	precocene I	ADHFE1 GPT	1.53e-04	8	54	2	CID000028619
Drug	lactosyl lysosphingolipid	RYR1 RYR3	1.97e-04	9	54	2	CID006439268
Drug	fospirate	ATM CNR2	1.97e-04	9	54	2	CID000021805
Drug	FLA 365	RYR1 RYR3	1.97e-04	9	54	2	CID000072776
Drug	polyethylenimine	ADHFE1 TF RYR1 RYR3	2.42e-04	128	54	4	CID000009033
Drug	glycine propionyl carnitine	GPT ATM	2.45e-04	10	54	2	ctd:C000588486
Drug	AC1N38XE	RYR1 RYR3	2.45e-04	10	54	2	CID004060965
Drug	PCB 95	RYR1 RYR3	2.45e-04	10	54	2	CID000038012
Drug	N-carbamoyl-L-methionine	GPT ATM TF	2.57e-04	52	54	3	CID000121697
Drug	PCB 66	RYR1 RYR3	3.00e-04	11	54	2	CID000036185
Drug	hydroxyacetophenone	ADHFE1 RYR1	3.00e-04	11	54	2	CID000068490
Drug	R 478	RYR1 RYR3	3.00e-04	11	54	2	CID000084223
Drug	8-amino-cADPR	RYR1 RYR3	3.00e-04	11	54	2	CID003081323
Drug	L-tert-leucine	ADHFE1 C3	3.00e-04	11	54	2	CID000164608
Drug	arachidonoylglycine	ADHFE1 CNR2	3.00e-04	11	54	2	CID000004345
Drug	(2S,3R)-Sphingosine	FA2H GPT C3 MUSK RYR1 RYR3	3.09e-04	389	54	6	CID000001104
Drug	Busulfan	ATM KIT TF	3.37e-04	57	54	3	ctd:D002066
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR3	9.85e-06	3	54	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR3	9.85e-06	3	54	2	DOID:8545 (implicated_via_orthology)
Disease	Pancreatic Neoplasm	CFLAR ANXA10 ATM CNR2	3.45e-05	100	54	4	C0030297
Disease	Malignant neoplasm of pancreas	CFLAR ANXA10 ATM CNR2	3.73e-05	102	54	4	C0346647
Disease	Paratuberculosis	C3 TF	4.91e-05	6	54	2	C0030524
Disease	acute myocardial infarction (is_marker_for)	SERPING1 C3	6.86e-05	7	54	2	DOID:9408 (is_marker_for)
Disease	Acute Myeloid Leukemia, M1	ANXA6 KIT CNR2 CCND2	8.24e-05	125	54	4	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	ANXA6 KIT CNR2 CCND2	8.24e-05	125	54	4	C1879321
Disease	Drug-Induced Liver Disease	ANXA6 GPT SERPING1 C3 TF CAP1	9.41e-05	404	54	6	C0860207
Disease	Drug-Induced Acute Liver Injury	ANXA6 GPT SERPING1 C3 TF CAP1	9.41e-05	404	54	6	C3658290
Disease	Hepatitis, Toxic	ANXA6 GPT SERPING1 C3 TF CAP1	9.41e-05	404	54	6	C0019193
Disease	Chemically-Induced Liver Toxicity	ANXA6 GPT SERPING1 C3 TF CAP1	9.41e-05	404	54	6	C4279912
Disease	Chemical and Drug Induced Liver Injury	ANXA6 GPT SERPING1 C3 TF CAP1	9.41e-05	404	54	6	C4277682
Disease	Hepatitis, Drug-Induced	ANXA6 GPT SERPING1 C3 TF CAP1	9.41e-05	404	54	6	C1262760
Disease	granulosa cell tumor (is_marker_for)	KIT CCND2	1.79e-04	11	54	2	DOID:2999 (is_marker_for)
Disease	colorectal cancer (is_marker_for)	EEF2 CHD4 ATM CCND2	1.98e-04	157	54	4	DOID:9256 (is_marker_for)
Disease	Leukemia, Myelocytic, Acute	ANXA6 KIT CNR2 CCND2	2.87e-04	173	54	4	C0023467
Disease	delta-5 desaturase measurement, response to polyunsaturated fatty acid supplementation	HDGFL2 MUSK	4.39e-04	17	54	2	EFO_0007764, EFO_0009131
Disease	COVID-19 (is_implicated_in)	SERPING1 C3	6.75e-04	21	54	2	DOID:0080600 (is_implicated_in)
Disease	albuminuria	SPHKAP NXPE2 PRKAG2	6.90e-04	94	54	3	EFO_0004285
Disease	Immunologic Deficiency Syndromes	C3 ATM	8.11e-04	23	54	2	C0021051
Disease	lung squamous cell carcinoma (is_implicated_in)	ATM CCND2	8.84e-04	24	54	2	DOID:3907 (is_implicated_in)
Disease	Schizophrenia	SLC6A11 NLGN2 CHD4 ATM TF CNR2 CCND2	1.09e-03	883	54	7	C0036341
Disease	Nephrotic Syndrome	XPO5 TF	1.12e-03	27	54	2	C0027726
Disease	macular degeneration (is_implicated_in)	SERPING1 C3	1.12e-03	27	54	2	DOID:4448 (is_implicated_in)
Disease	lung small cell carcinoma (is_implicated_in)	XPO5 ATM	1.21e-03	28	54	2	DOID:5409 (is_implicated_in)
Disease	severe acute respiratory syndrome, COVID-19	KCNIP4 CHSY3 PRKAG2 NUBPL CNR2	1.34e-03	447	54	5	EFO_0000694, MONDO_0100096
Disease	Age related macular degeneration	C3 RPGR	1.38e-03	30	54	2	C0242383
Disease	colorectal cancer (is_implicated_in)	XPO5 CHD4 ATM	1.43e-03	121	54	3	DOID:9256 (is_implicated_in)
Disease	Complement deficiency disease	SERPING1 C3	1.67e-03	33	54	2	C0272242
Disease	Malignant Neoplasms	ATM KIT CCND2	1.68e-03	128	54	3	C0006826
Disease	nephroblastoma (is_marker_for)	KIT CCND2	1.78e-03	34	54	2	DOID:2154 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EEYPMAAPKVRFMTK	UBE2NL	61	Q5JXB2
FHSFKKVLMEMGPPY	GPT	286	P24298
KFLQLFMSDMPKPAF	PRKAG2	406	Q9UGJ0
SDHFKDVMAGLMYPP	ANXA10	76	Q9UJ72
RFMKKLMFPVGYGVP	ADGRE2	641	Q9UHX3
KGMFLISAAPPEMYE	ARHGEF2	536	Q92974
MAPKPGPYVKEMNDA	CAP1	146	Q01518
PKYFKPGMPFDLMVF	C3	361	P01024
MGDSCPYLAGKPKMF	CFLAR	341	O15519
GLMMPPAHYDAKQLK	ANXA6	431	P08133
PMKDYMILSGPQKTA	CNR2	21	P34972
KKESFAPGTMYKPFG	RBM41	46	Q96IZ5
KSAKPMVFAGMYPLD	GUF1	351	Q8N442
DFKFAMYPPSMIATG	CCND2	191	P30279
FHALKDILGPPMYEM	LONP2	631	Q86WA8
MIRGKKNFLPPSYLM	NEMF	636	O60524
YMDMKPGVSYVVPTK	KIT	721	P10721
PGMPVDSKFYKMIKE	KIT	871	P10721
YMPPKDPGYSTEMKE	ENOSF1	406	Q7L5Y1
NKDGSKPLLCHYMMP	PEX3	226	P56589
SDPPYMEMKGKLSAK	CSPP1	61	Q1MSJ5
MTKHPLAMYPNLGKD	FAM47B	126	Q8NA70
MMGKCTYPVLKEDAP	KCNIP4	191	Q6PIL6
MPHAFKPGDLVFAKM	HDGFL2	1	Q7Z4V5
MASEVPYASGMPIKK	PIPSL	1	A2A3N6
YTVAVPKSMFPGLFM	FA2H	206	Q7L5A8
EGKTPYHPCIYEKMM	B3GNT5	306	Q9BYG0
RDGMKIPTYKFLPLM	ATM	2506	Q13315
FSLTEPMKKMFQCPY	BABAM1	226	Q9NWV8
MPAGVPMSTYLKMFA	BRAWNIN	1	Q69YU5
KMVSMKPPGFQASLA	AKNA	836	Q7Z591
KVPMMNSKKYPVAHF	SERPING1	321	P05155
KSCDPKGPLMMYISK	EEF2	386	P13639
HPYLFPVAAMEAPKM	CHD4	1021	Q14839
LPMFGIMPSKKVASA	SLC13A1	66	Q9BZW2
KTYMMSNGYKPAPLD	RYR1	956	P21817
KKPVMLFLHGGSYME	NLGN2	176	Q8NFZ4
VDVYGPSVPKMMNLK	NUBPL	106	Q8TB37
GMSYPISGLVKMYKA	ADHFE1	331	Q8IWW8
KTMDAGCKPYMAPER	MAP2K3	221	P46734
KKMSPFFGNLPDRGM	RPGR	666	Q92834
NEVMMKKYSPSDPAF	RAB11FIP1	1206	Q6WKZ4
PKDAYFSMMDKDVPS	SPHKAP	341	Q2M3C7
GMKTPFPSGYTLKKM	NXPE2	321	Q96DL1
MGIFAKPDHVKMTYP	MRM3	186	Q9HC36
GQPYFEAFKKKMPIA	NEPRO	231	Q6NW34
YPKAEMTLIPMKGEF	CHSY3	681	Q70JA7
SITGLPPAMQKVMYK	UBFD1	116	O14562
FLKVPPRMDAKMYLG	TF	321	P02787
VKLPKNYMMSNGYKP	RYR3	951	Q15413
FMASKKMQLEFPPSL	IGHMBP2	736	P38935
LYAPEMLAKMAEPFT	XPO5	786	Q9HAV4
GLAFIAYPKAVTMMP	SLC6A11	376	P48066
YKTIKVPMMYGAGKF	SERPINA10	261	Q9UK55
SKFSPMSYPQMKPKS	ZNF462	336	Q96JM2
MFPSYKVKVTGMNPK	TBX4	96	P57082
GLLPYEPFTMVAVKM	MUSK	596	O15146