Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

CD248 NOTCH2 NOTCH3 NOTCH4

3.44e-04749104GO:0005509
GeneOntologyBiologicalProcesspositive regulation of miRNA transcription

EGFR NOTCH2 NOTCH3

2.91e-0661103GO:1902895
GeneOntologyBiologicalProcessglomerulus vasculature morphogenesis

NOTCH2 NOTCH3

3.17e-066102GO:0072103
GeneOntologyBiologicalProcessglomerular capillary formation

NOTCH2 NOTCH3

3.17e-066102GO:0072104
GeneOntologyBiologicalProcessrenal system vasculature morphogenesis

NOTCH2 NOTCH3

4.44e-067102GO:0061438
GeneOntologyBiologicalProcesskidney vasculature morphogenesis

NOTCH2 NOTCH3

4.44e-067102GO:0061439
GeneOntologyBiologicalProcesspositive regulation of miRNA metabolic process

EGFR NOTCH2 NOTCH3

5.01e-0673103GO:2000630
GeneOntologyBiologicalProcessregulation of miRNA transcription

EGFR NOTCH2 NOTCH3

7.39e-0683103GO:1902893
GeneOntologyBiologicalProcessmiRNA transcription

EGFR NOTCH2 NOTCH3

7.66e-0684103GO:0061614
GeneOntologyBiologicalProcessglomerulus morphogenesis

NOTCH2 NOTCH3

1.16e-0511102GO:0072102
GeneOntologyBiologicalProcessregulation of miRNA metabolic process

EGFR NOTCH2 NOTCH3

1.41e-05103103GO:2000628
GeneOntologyBiologicalProcessmiRNA metabolic process

EGFR NOTCH2 NOTCH3

2.18e-05119103GO:0010586
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell differentiation

NOTCH2 NOTCH4

7.94e-0528102GO:0051152
GeneOntologyBiologicalProcessglomerulus vasculature development

NOTCH2 NOTCH3

9.14e-0530102GO:0072012
GeneOntologyBiologicalProcesskidney vasculature development

NOTCH2 NOTCH3

9.76e-0531102GO:0061440
GeneOntologyBiologicalProcessrenal system vasculature development

NOTCH2 NOTCH3

9.76e-0531102GO:0061437
GeneOntologyBiologicalProcessNotch signaling pathway

NOTCH2 NOTCH3 NOTCH4

1.18e-04210103GO:0007219
GeneOntologyBiologicalProcesspositive regulation of BMP signaling pathway

NOTCH2 KCP

1.80e-0442102GO:0030513
GeneOntologyBiologicalProcesscell fate determination

NOTCH2 NOTCH4

2.56e-0450102GO:0001709
GeneOntologyBiologicalProcessregulation of smooth muscle cell differentiation

NOTCH2 NOTCH4

2.99e-0454102GO:0051150
GeneOntologyBiologicalProcesscell fate commitment

NOTCH2 NOTCH3 NOTCH4

4.81e-04338103GO:0045165
GeneOntologyBiologicalProcessglomerulus development

NOTCH2 NOTCH3

6.07e-0477102GO:0032835
GeneOntologyBiologicalProcesspositive regulation of fibroblast proliferation

CD248 EGFR

7.39e-0485102GO:0048146
GeneOntologyBiologicalProcessartery morphogenesis

NOTCH3 NOTCH4

8.65e-0492102GO:0048844
GeneOntologyBiologicalProcesssmooth muscle cell differentiation

NOTCH2 NOTCH4

1.00e-0399102GO:0051145
GeneOntologyBiologicalProcessneuroinflammatory response

EGFR DAGLA

1.04e-03101102GO:0150076
GeneOntologyBiologicalProcessneuroblast proliferation

NOTCH2 DAGLA

1.10e-03104102GO:0007405
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

NOTCH2 NOTCH4

1.15e-03106102GO:0051149
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

NOTCH2 KCP

1.35e-03115102GO:0090100
GeneOntologyBiologicalProcesstube morphogenesis

EGFR NOTCH2 NOTCH3 NOTCH4

1.42e-031125104GO:0035239
GeneOntologyBiologicalProcessbone remodeling

EGFR NOTCH2

1.64e-03127102GO:0046849
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

NOTCH2 KCP

1.74e-03131102GO:0030510
GeneOntologyBiologicalProcesspositive regulation of cell population proliferation

CD248 EGFR NOTCH2 NOTCH3

1.75e-031190104GO:0008284
GeneOntologyBiologicalProcesscell morphogenesis

EGFR NOTCH2 NOTCH3 NOTCH4

1.77e-031194104GO:0000902
GeneOntologyBiologicalProcessartery development

NOTCH3 NOTCH4

1.80e-03133102GO:0060840
GeneOntologyBiologicalProcessregulation of fibroblast proliferation

CD248 EGFR

1.85e-03135102GO:0048145
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell proliferation

EGFR NOTCH3

1.93e-03138102GO:0048661
GeneOntologyBiologicalProcessgland development

EGFR NOTCH2 NOTCH4

2.05e-03558103GO:0048732
GeneOntologyBiologicalProcessfibroblast proliferation

CD248 EGFR

2.58e-03160102GO:0048144
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

EGFR NOTCH2 NOTCH4

2.76e-03619103GO:0002009
GeneOntologyBiologicalProcessnephron development

NOTCH2 NOTCH3

3.05e-03174102GO:0072006
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

EGFR NOTCH2 NOTCH3 NOTCH4

3.10e-031390104GO:0045944
GeneOntologyBiologicalProcessgland morphogenesis

EGFR NOTCH2

3.18e-03178102GO:0022612
GeneOntologyBiologicalProcesstube development

EGFR NOTCH2 NOTCH3 NOTCH4

3.20e-031402104GO:0035295
GeneOntologyBiologicalProcesscirculatory system development

EGFR NOTCH2 NOTCH3 NOTCH4

3.55e-031442104GO:0072359
GeneOntologyBiologicalProcessBMP signaling pathway

NOTCH2 KCP

3.88e-03197102GO:0030509
GeneOntologyBiologicalProcessplacenta development

EGFR NOTCH2

3.88e-03197102GO:0001890
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

NOTCH2 NOTCH4

3.96e-03199102GO:0051147
GeneOntologyBiologicalProcessangiogenesis

NOTCH2 NOTCH3 NOTCH4

4.03e-03708103GO:0001525
GeneOntologyBiologicalProcessliver development

EGFR NOTCH2

4.08e-03202102GO:0001889
GeneOntologyBiologicalProcesshepaticobiliary system development

EGFR NOTCH2

4.20e-03205102GO:0061008
GeneOntologyBiologicalProcessresponse to BMP

NOTCH2 KCP

4.61e-03215102GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

NOTCH2 KCP

4.61e-03215102GO:0071773
GeneOntologyBiologicalProcesstissue morphogenesis

EGFR NOTCH2 NOTCH4

4.74e-03750103GO:0048729
GeneOntologyBiologicalProcessregulation of smooth muscle cell proliferation

EGFR NOTCH3

5.16e-03228102GO:0048660
GeneOntologyBiologicalProcessneural precursor cell proliferation

NOTCH2 DAGLA

5.39e-03233102GO:0061351
GeneOntologyBiologicalProcesssmooth muscle cell proliferation

EGFR NOTCH3

5.57e-03237102GO:0048659
GeneOntologyBiologicalProcesspositive regulation of ERK1 and ERK2 cascade

EGFR NOTCH2

5.71e-03240102GO:0070374
GeneOntologyBiologicalProcessneuron projection morphogenesis

EGFR NOTCH2 NOTCH3

5.73e-03802103GO:0048812
GeneOntologyBiologicalProcessblood vessel morphogenesis

NOTCH2 NOTCH3 NOTCH4

6.03e-03817103GO:0048514
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

EGFR NOTCH2 NOTCH3

6.07e-03819103GO:0120039
GeneOntologyBiologicalProcesscircadian rhythm

EGFR AGRP

6.08e-03248102GO:0007623
GeneOntologyBiologicalProcesscell projection morphogenesis

EGFR NOTCH2 NOTCH3

6.22e-03826103GO:0048858
GeneOntologyCellularComponentcell surface

CD248 EGFR NOTCH2 NOTCH3 NOTCH4

8.46e-051111105GO:0009986
GeneOntologyCellularComponentGolgi membrane

EGFR NOTCH2 NOTCH3 NOTCH4

2.50e-04721104GO:0000139
GeneOntologyCellularComponentreceptor complex

EGFR NOTCH2 NOTCH3

2.22e-03581103GO:0043235
GeneOntologyCellularComponentendoplasmic reticulum membrane

EGFR NOTCH2 NOTCH3 NOTCH4

2.26e-031293104GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

EGFR NOTCH2 NOTCH3 NOTCH4

2.30e-031299104GO:0098827
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

EGFR NOTCH2 NOTCH3 NOTCH4

2.49e-031327104GO:0042175
GeneOntologyCellularComponentleading edge membrane

EGFR DAGLA

4.29e-03210102GO:0031256
GeneOntologyCellularComponentearly endosome membrane

EGFR DAGLA

4.37e-03212102GO:0031901
HumanPhenoPlatybasia

NOTCH2 NOTCH3

1.04e-041752HP:0002691
HumanPhenoDural ectasia

THSD4 NOTCH3

2.11e-042452HP:0100775
HumanPhenoBiconcave vertebral bodies

NOTCH2 NOTCH3

2.29e-042552HP:0004586
HumanPhenoAbnormal spinal meningeal morphology

THSD4 NOTCH3

2.29e-042552HP:0010303
HumanPhenoSyringomyelia

NOTCH2 NOTCH3

4.02e-043352HP:0003396
HumanPhenoIncreased blood pressure

THSD4 EGFR NOTCH2 NOTCH3

4.51e-0450854HP:0032263
HumanPhenoHypertension

THSD4 EGFR NOTCH2 NOTCH3

4.51e-0450854HP:0000822
HumanPhenoIschemic stroke

THSD4 NOTCH3

5.34e-043852HP:0002140
HumanPhenoCerebral infarct

THSD4 NOTCH3

5.63e-043952HP:0025722
HumanPhenoAbnormal systemic blood pressure

THSD4 EGFR NOTCH2 NOTCH3

7.03e-0456954HP:0030972
HumanPhenoSpinal cord lesion

NOTCH2 NOTCH3

7.84e-044652HP:0100561
MousePhenodecreased trabecular bone connectivity density

NOTCH2 NOTCH3

5.50e-0516102MP:0010933
MousePhenoabnormal osteoblast morphology

EGFR NOTCH2 NOTCH3

1.05e-04137103MP:0004986
MousePhenoabnormal trabecular bone connectivity density

NOTCH2 NOTCH3

1.60e-0427102MP:0010931
DomainNotch_NODP_dom

NOTCH2 NOTCH3 NOTCH4

4.42e-104103IPR011656
DomainNotch_NOD_dom

NOTCH2 NOTCH3 NOTCH4

4.42e-104103IPR010660
DomainNOD

NOTCH2 NOTCH3 NOTCH4

4.42e-104103PF06816
DomainNotch

NOTCH2 NOTCH3 NOTCH4

4.42e-104103IPR008297
DomainNOD

NOTCH2 NOTCH3 NOTCH4

4.42e-104103SM01338
DomainNODP

NOTCH2 NOTCH3 NOTCH4

4.42e-104103SM01339
DomainNODP

NOTCH2 NOTCH3 NOTCH4

4.42e-104103PF07684
DomainLNR

NOTCH2 NOTCH3 NOTCH4

1.10e-095103PS50258
DomainNotch_dom

NOTCH2 NOTCH3 NOTCH4

3.86e-097103IPR000800
DomainNotch

NOTCH2 NOTCH3 NOTCH4

3.86e-097103PF00066
DomainNL

NOTCH2 NOTCH3 NOTCH4

3.86e-097103SM00004
DomainGrowth_fac_rcpt_

CD248 EGFR NOTCH2 NOTCH3 NOTCH4

9.29e-09156105IPR009030
DomainEGF_CA

CD248 NOTCH2 NOTCH3 NOTCH4

8.61e-0886104PF07645
DomainEGF_Ca-bd_CS

CD248 NOTCH2 NOTCH3 NOTCH4

1.40e-0797104IPR018097
DomainEGF_CA

CD248 NOTCH2 NOTCH3 NOTCH4

1.52e-0799104PS01187
DomainEGF-type_Asp/Asn_hydroxyl_site

CD248 NOTCH2 NOTCH3 NOTCH4

2.00e-07106104IPR000152
DomainEGF_CA

CD248 NOTCH2 NOTCH3 NOTCH4

3.53e-07122104SM00179
DomainhEGF

NOTCH2 NOTCH3 NOTCH4

3.60e-0728103PF12661
DomainEGF-like_Ca-bd_dom

CD248 NOTCH2 NOTCH3 NOTCH4

3.77e-07124104IPR001881
DomainEGF

CD248 NOTCH2 NOTCH3 NOTCH4

4.02e-07126104PF00008
DomainDUF3454_notch

NOTCH2 NOTCH3

7.74e-073102IPR024600
DomainDUF3454

NOTCH2 NOTCH3

7.74e-073102SM01334
DomainDUF3454

NOTCH2 NOTCH3

7.74e-073102PF11936
DomainEGF

CD248 NOTCH2 NOTCH3 NOTCH4

4.83e-06235104SM00181
DomainEGF_3

CD248 NOTCH2 NOTCH3 NOTCH4

4.83e-06235104PS50026
DomainEGF-like_dom

CD248 NOTCH2 NOTCH3 NOTCH4

6.08e-06249104IPR000742
DomainEGF_1

CD248 NOTCH2 NOTCH3 NOTCH4

6.68e-06255104PS00022
DomainEGF-like_CS

CD248 NOTCH2 NOTCH3 NOTCH4

7.33e-06261104IPR013032
DomainEGF_2

CD248 NOTCH2 NOTCH3 NOTCH4

7.78e-06265104PS01186
DomainASX_HYDROXYL

NOTCH2 NOTCH3 NOTCH4

1.74e-05100103PS00010
DomainAnk_2

NOTCH2 NOTCH3 NOTCH4

1.70e-04215103PF12796
DomainAnk

NOTCH2 NOTCH3 NOTCH4

2.02e-04228103PF00023
Domain-

NOTCH2 NOTCH3 NOTCH4

2.59e-042481031.25.40.20
DomainANK

NOTCH2 NOTCH3 NOTCH4

2.68e-04251103SM00248
DomainANK_REPEAT

NOTCH2 NOTCH3 NOTCH4

2.75e-04253103PS50088
DomainAnkyrin_rpt-contain_dom

NOTCH2 NOTCH3 NOTCH4

2.78e-04254103IPR020683
DomainANK_REP_REGION

NOTCH2 NOTCH3 NOTCH4

2.78e-04254103PS50297
DomainAnkyrin_rpt

NOTCH2 NOTCH3 NOTCH4

3.04e-04262103IPR002110
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

EGFR NOTCH2 NOTCH3 NOTCH4

4.50e-102484M11190
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH2 NOTCH3 NOTCH4

1.20e-09583M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH2 NOTCH3 NOTCH4

2.40e-09683M27068
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH2 NOTCH3 NOTCH4

1.98e-081183M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH2 NOTCH3 NOTCH4

2.63e-081283M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH2 NOTCH3 NOTCH4

2.63e-081283M47533
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

THSD4 NOTCH2 NOTCH3 NOTCH4

3.42e-086884M27303
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3 NOTCH4

3.42e-081383M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH2 NOTCH3 NOTCH4

3.42e-081383M47534
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

EGFR NOTCH2 NOTCH3 NOTCH4

7.31e-088284MM15922
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH2 NOTCH3 NOTCH4

9.75e-081883M614
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH2 NOTCH3 NOTCH4

3.49e-072783M39545
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH2 NOTCH3 NOTCH4

3.90e-072883M6177
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

THSD4 NOTCH2 NOTCH3 NOTCH4

6.89e-0714384M27275
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH2 NOTCH3 NOTCH4

7.12e-073483M39390
PathwayWP_BREAST_CANCER_PATHWAY

EGFR NOTCH2 NOTCH3 NOTCH4

9.27e-0715484M39739
PathwayREACTOME_SIGNALING_BY_NOTCH

EGFR NOTCH3 NOTCH4

1.09e-063983MM14604
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH2 NOTCH3 NOTCH4

1.68e-064583M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3 NOTCH4

1.80e-064683MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH2 NOTCH3 NOTCH4

1.92e-064783M7946
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH3 NOTCH4

2.82e-06582MM14733
PathwayPID_NOTCH_PATHWAY

NOTCH2 NOTCH3 NOTCH4

3.84e-065983M17
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH2 NOTCH3 NOTCH4

4.25e-066183M39540
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH3 NOTCH4

5.91e-06782MM14734
PathwayREACTOME_SIGNALING_BY_NOTCH

EGFR NOTCH2 NOTCH3 NOTCH4

6.00e-0624684M10189
PathwayREACTOME_DISEASES_OF_METABOLISM

THSD4 NOTCH2 NOTCH3 NOTCH4

6.39e-0625084M27554
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH2 NOTCH3 NOTCH4

1.72e-059783MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

NOTCH2 NOTCH3 NOTCH4

1.95e-0510183M39448
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

NOTCH2 NOTCH3 NOTCH4

3.11e-0511883M39852
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH2 NOTCH3 NOTCH4

3.18e-0511983M607
PathwayPID_SYNDECAN_3_PATHWAY

EGFR AGRP

3.82e-051782M251
PathwayREACTOME_SIGNALING_BY_NOTCH3

EGFR NOTCH3

4.80e-051982MM15594
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH2 NOTCH4

5.33e-052082M27881
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH3 NOTCH4

7.09e-052382MM14954
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

NOTCH2 NOTCH3 NOTCH4

7.85e-0516183M39770
PathwayREACTOME_NOTCH3_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

EGFR NOTCH3

8.40e-052582M27879
PathwayWP_CANCER_PATHWAYS

EGFR NOTCH2 NOTCH3 NOTCH4

1.03e-0450784M48302
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH3 NOTCH4

1.86e-043782M39506
PathwayREACTOME_SIGNALING_BY_NOTCH3

EGFR NOTCH3

3.27e-044982M618
PathwayREACTOME_RNA_POLYMERASE_II_TRANSCRIPTION

EGFR AGRP NOTCH2 NOTCH3 NOTCH4

3.97e-04138785M734
PathwayWP_HEAD_AND_NECK_SQUAMOUS_CELL_CARCINOMA

EGFR NOTCH2

7.46e-047482M39857
PathwayREACTOME_SIGNALING_BY_NOTCH4

NOTCH2 NOTCH4

9.15e-048282M594
PathwayWP_HAIR_FOLLICLE_DEVELOPMENT_CYTODIFFERENTIATION_STAGE_3_OF_3

EGFR NOTCH2

1.03e-038782M39465
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

EGFR DAGLA

5.83e-0321082MM15043
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

EGFR DAGLA

6.21e-0321782M18437
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411328061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411320069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411319404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411328669409
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411324151014
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411311401408
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411310194420
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH2 NOTCH3 NOTCH4

9.41e-1141138898100
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411311459941
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411318184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411315917835
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411323444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH2 NOTCH3 NOTCH4

9.41e-11411317920003
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

NOTCH2 NOTCH3 NOTCH4

2.35e-10511321726900
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH2 NOTCH3 NOTCH4

2.35e-10511321124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH2 NOTCH3 NOTCH4

2.35e-10511323675950
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH2 NOTCH3 NOTCH4

2.35e-10511311101851
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH2 NOTCH3 NOTCH4

2.35e-10511315882997
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH2 NOTCH3 NOTCH4

4.70e-1061139111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611320870902
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611312244553
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611319503073
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611318299578
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611315019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611322615412
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH2 NOTCH3 NOTCH4

4.70e-10611321991352
Pubmed

Human ligands of the Notch receptor.

NOTCH2 NOTCH3 NOTCH4

8.23e-10711310079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH2 NOTCH3 NOTCH4

8.23e-10711312846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH2 NOTCH3 NOTCH4

8.23e-10711311518718
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH2 NOTCH3 NOTCH4

1.32e-09811322156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH2 NOTCH3 NOTCH4

1.32e-09811312242716
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH2 NOTCH3 NOTCH4

1.32e-0981139858718
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH2 NOTCH3 NOTCH4

1.97e-09911311118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH2 NOTCH3 NOTCH4

1.97e-09911316245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH2 NOTCH3 NOTCH4

1.97e-09911312370315
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH2 NOTCH3 NOTCH4

2.82e-091011323665443
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH2 NOTCH3 NOTCH4

2.82e-091011333915108
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH2 NOTCH3 NOTCH4

3.88e-091111316607638
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH2 NOTCH3 NOTCH4

3.88e-091111315499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH2 NOTCH3 NOTCH4

3.88e-091111310878608
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH2 NOTCH3 NOTCH4

3.88e-09111139187150
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH2 NOTCH3 NOTCH4

3.88e-091111312866128
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH2 NOTCH3 NOTCH4

5.17e-091211310952889
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

NOTCH2 NOTCH3 NOTCH4

5.17e-091211315465494
Pubmed

A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.

NOTCH2 NOTCH3 NOTCH4

6.72e-091311332929274
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

NOTCH2 NOTCH3 NOTCH4

6.72e-091311311578869
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

NOTCH2 NOTCH3 NOTCH4

6.72e-091311320558824
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

NOTCH2 NOTCH3 NOTCH4

8.55e-091411334824237
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

NOTCH2 NOTCH3 NOTCH4

8.55e-091411314757642
Pubmed

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

NOTCH2 NOTCH3 NOTCH4

1.07e-081511314672936
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

NOTCH2 NOTCH3 NOTCH4

1.07e-081511312971992
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

NOTCH2 NOTCH3 NOTCH4

1.32e-081611312617809
Pubmed

Notch gene expression during pancreatic organogenesis.

NOTCH2 NOTCH3 NOTCH4

1.32e-081611310842072
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

NOTCH2 NOTCH3 NOTCH4

1.32e-081611317273555
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

NOTCH2 NOTCH3 NOTCH4

1.32e-081611311739954
Pubmed

The Cellular Prion Protein Controls Notch Signaling in Neural Stem/Progenitor Cells.

EGFR NOTCH2 NOTCH3

1.32e-081611327641601
Pubmed

Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.

EGFR NOTCH2 NOTCH3

1.32e-081611332161758
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

NOTCH2 NOTCH3 NOTCH4

1.60e-081711318694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

NOTCH2 NOTCH3 NOTCH4

1.60e-081711315821257
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

NOTCH2 NOTCH3 NOTCH4

1.60e-081711339315665
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

NOTCH2 NOTCH3 NOTCH4

1.92e-081811318093989
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

NOTCH2 NOTCH3 NOTCH4

1.92e-081811315689374
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

NOTCH2 NOTCH3 NOTCH4

2.27e-081911316518823
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

NOTCH2 NOTCH3 NOTCH4

3.12e-082111328656980
Pubmed

Conversion of biliary system to pancreatic tissue in Hes1-deficient mice.

NOTCH2 NOTCH3 NOTCH4

3.12e-082111314702043
Pubmed

E3 ubiquitin ligase FBXW7 balances airway cell fates.

NOTCH2 NOTCH3 NOTCH4

3.61e-082211334998785
Pubmed

Notch promotes epithelial-mesenchymal transition during cardiac development and oncogenic transformation.

NOTCH2 NOTCH3 NOTCH4

4.15e-082311314701881
Pubmed

Loss of function of the maternal membrane oestrogen receptor ERα alters expansion of trophoblast cells and impacts mouse fertility.

NOTCH2 NOTCH3 NOTCH4

4.15e-082311336239412
Pubmed

Rbpj regulates development of prosensory cells in the mammalian inner ear.

NOTCH2 NOTCH3 NOTCH4

4.75e-082411321420948
Pubmed

The Krüppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice.

NOTCH2 NOTCH3 NOTCH4

5.39e-082511321786021
Pubmed

Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning.

NOTCH2 NOTCH3 NOTCH4

6.09e-082611325446530
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

NOTCH2 NOTCH3 NOTCH4

6.09e-082611319369401
Pubmed

Notch signaling prevents mucous metaplasia in mouse conducting airways during postnatal development.

NOTCH2 NOTCH3 NOTCH4

6.86e-082711321791528
Pubmed

Cdc42-mediated tubulogenesis controls cell specification.

NOTCH2 NOTCH3 NOTCH4

7.68e-082811319914171
Pubmed

Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.

NOTCH2 NOTCH3 NOTCH4

8.56e-082911325535917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

NOTCH2 NOTCH3 NOTCH4

8.56e-082911321402740
Pubmed

Notch receptors and hematopoiesis.

NOTCH2 NOTCH4

9.09e-08211211532344
Pubmed

Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.

NOTCH3 NOTCH4

9.09e-08211233665264
Pubmed

Expression of notch family proteins in placentas from patients with early-onset severe preeclampsia.

NOTCH2 NOTCH3

9.09e-08211224336671
Pubmed

NOTCH Single Nucleotide Polymorphisms in the Predisposition of Breast and Colorectal Cancers in Saudi Patients.

NOTCH2 NOTCH3

9.09e-08211234257585
Pubmed

Aberrant Notch3 and Notch4 expression in human hepatocellular carcinoma.

NOTCH3 NOTCH4

9.09e-08211217696940
Pubmed

Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.

NOTCH3 NOTCH4

9.09e-08211225658374
Pubmed

Effects of Notch2 and Notch3 on Cell Proliferation and Apoptosis of Trophoblast Cell Lines.

NOTCH2 NOTCH3

9.09e-08211226640406
Pubmed

Notch2 and Notch3 function together to regulate vascular smooth muscle development.

NOTCH2 NOTCH3

9.09e-08211222615991
Pubmed

A genetic determinant that specifically regulates the frequency of hematopoietic stem cells.

NOTCH3 NOTCH4

9.09e-08211211777956
Pubmed

notch2, notch4 gene polymorphisms in psoriasis vulgaris.

NOTCH2 NOTCH4

9.09e-08211223587900
Pubmed

Inflammation dysregulates Notch signaling in endothelial cells: implication of Notch2 and Notch4 to endothelial dysfunction.

NOTCH2 NOTCH4

9.09e-08211220643108
Pubmed

Notch signaling regulates ovarian follicle formation and coordinates follicular growth.

NOTCH2 NOTCH3 NOTCH4

9.51e-083011324552588
Pubmed

p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation.

EGFR NOTCH2 NOTCH3

9.51e-083011316524929
Pubmed

ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling.

NOTCH2 NOTCH3 NOTCH4

1.05e-073111337573008
Pubmed

Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis.

NOTCH2 NOTCH3 NOTCH4

1.40e-073411317015435
Pubmed

Differential Notch signaling in the epicardium is required for cardiac inflow development and coronary vessel morphogenesis.

NOTCH2 NOTCH3 NOTCH4

1.40e-073411321311046
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

NOTCH2 NOTCH3 NOTCH4

1.53e-073511321252157
Pubmed

Notch signaling in postnatal pituitary expansion: proliferation, progenitors, and cell specification.

NOTCH2 NOTCH3 NOTCH4

1.82e-073711324673559
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

NOTCH2 NOTCH3 NOTCH4

2.49e-074111322675208
Pubmed

Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.

EGFR NOTCH3

2.73e-07311219881544
Pubmed

Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.

NOTCH2 NOTCH3

2.73e-0731127615640
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH3 NOTCH4

2.73e-07311225846406
InteractionMAML2 interactions

NOTCH2 NOTCH3 NOTCH4

8.19e-0817113int:MAML2
InteractionMAML3 interactions

NOTCH2 NOTCH3 NOTCH4

1.37e-0720113int:MAML3
InteractionNOTCH4 interactions

NOTCH2 NOTCH3 NOTCH4

1.60e-0721113int:NOTCH4
InteractionFBXO2 interactions

THSD4 EGFR CACHD1 NOTCH2 NOTCH3

1.44e-06411115int:FBXO2
InteractionNOTCH2 interactions

EGFR AGRP NOTCH2 NOTCH3 NOTCH4

1.66e-06423115int:NOTCH2
InteractionCD248 interactions

CD248 EGFR

5.68e-067112int:CD248
InteractionMAML1 interactions

NOTCH2 NOTCH3 NOTCH4

7.37e-0673113int:MAML1
InteractionEGFL7 interactions

NOTCH2 NOTCH3 NOTCH4

8.66e-0677113int:EGFL7
InteractionPSEN2 interactions

NOTCH2 NOTCH3 NOTCH4

1.21e-0586113int:PSEN2
InteractionDEFA1 interactions

EGFR CACHD1 NOTCH3

1.90e-05100113int:DEFA1
InteractionRABGGTB interactions

EGFR NOTCH2 NOTCH3

2.39e-05108113int:RABGGTB
InteractionIGSF5 interactions

NOTCH2 NOTCH3

2.46e-0514112int:IGSF5
InteractionAGRP interactions

AGRP NOTCH2

2.46e-0514112int:AGRP
InteractionNOTCH3 interactions

NOTCH2 NOTCH3 NOTCH4

2.74e-05113113int:NOTCH3
InteractionFBLN1 interactions

AGRP NOTCH2 NOTCH3

4.07e-05129113int:FBLN1
InteractionCASR interactions

NOTCH2 NOTCH3

6.22e-0522112int:CASR
InteractionNTN5 interactions

NOTCH2 NOTCH3

7.43e-0524112int:NTN5
InteractionLRATD2 interactions

EGFR NOTCH2

1.42e-0433112int:LRATD2
InteractionDLL1 interactions

NOTCH2 NOTCH3

1.88e-0438112int:DLL1
InteractionPSEN1 interactions

NOTCH2 NOTCH3 NOTCH4

2.18e-04227113int:PSEN1
InteractionJAG1 interactions

NOTCH2 NOTCH3

2.20e-0441112int:JAG1
InteractionLRRIQ1 interactions

NOTCH2 NOTCH3

2.42e-0443112int:LRRIQ1
InteractionTFAP2C interactions

CD248 EGFR

2.53e-0444112int:TFAP2C
InteractionGGH interactions

THSD4 EGFR CACHD1

2.66e-04243113int:GGH
InteractionANKRD44 interactions

NOTCH2 NOTCH3

3.01e-0448112int:ANKRD44
InteractionRBPJ interactions

NOTCH2 NOTCH3 NOTCH4

3.03e-04254113int:RBPJ
InteractionFOXD4L6 interactions

EGFR NOTCH2

3.14e-0449112int:FOXD4L6
InteractionDIRAS3 interactions

EGFR CACHD1 NOTCH2

3.32e-04262113int:DIRAS3
InteractionGRN interactions

EGFR AGRP NOTCH2

4.07e-04281113int:GRN
InteractionRET interactions

EGFR NOTCH2 NOTCH3

4.20e-04284113int:RET
InteractionPRG2 interactions

THSD4 NOTCH2 NOTCH3

4.25e-04285113int:PRG2
InteractionZFP41 interactions

NOTCH2 NOTCH3

4.25e-0457112int:ZFP41
InteractionWDR25 interactions

EGFR NOTCH3

4.40e-0458112int:WDR25
GeneFamilyAnkyrin repeat domain containing

NOTCH2 NOTCH3 NOTCH4

1.26e-0424283403
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH2 NOTCH3 NOTCH4

3.07e-0816113M2207
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

NOTCH2 NOTCH3 NOTCH4

3.07e-0816113MM1296
CoexpressionHU_FETAL_RETINA_FIBROBLAST

CD248 EGFR NOTCH2 NOTCH3

1.39e-05385114M39264
CoexpressionJEON_SMAD6_TARGETS_DN

EGFR NOTCH3

2.73e-0519112M13678
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

NOTCH3 NOTCH4

5.59e-0527112MM1135
CoexpressionSHIN_B_CELL_LYMPHOMA_CLUSTER_7

NOTCH3 NOTCH4

5.59e-0527112M1391
CoexpressionHALLMARK_NOTCH_SIGNALING

NOTCH2 NOTCH3

7.89e-0532112M5903
CoexpressionLIU_CDX2_TARGETS_UP

NOTCH3 NOTCH4

9.46e-0535112M16637
CoexpressionHAY_BONE_MARROW_STROMAL

THSD4 EGFR CACHD1 NOTCH3

2.04e-04767114M39209
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HPERIC

CD248 NOTCH2 KCP NOTCH3

2.34e-04795114M39050
CoexpressionFAN_EMBRYONIC_CTX_BIG_GROUPS_BRAIN_ENDOTHELIAL

CD248 NOTCH3 NOTCH4

4.07e-04365113M39018
CoexpressionJONES_OVARY_NK_CELL

NOTCH3 NOTCH4

6.15e-0489112M48353
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

THSD4 CD248 EGFR NOTCH2 NOTCH3

5.18e-05905115gudmap_kidney_P0_JuxtaGlom_Ren1_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#4_top-relative-expression-ranked_1000

THSD4 CD248 NOTCH3

9.25e-05179113gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k4_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_k-means-cluster#1_top-relative-expression-ranked_1000

THSD4 CACHD1 NOTCH2

2.09e-04236113gudmap_kidney_P3_CapMes_Crym_k1_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_1000

THSD4 NOTCH2 NOTCH3

3.95e-04293113gudmap_kidney_P0_JuxtaGlom_Ren1_k3_1000
CoexpressionAtlaskidney_P3_CapMes_Crym_top-relative-expression-ranked_1000

THSD4 CACHD1 NOTCH2 DAGLA

4.16e-04749114gudmap_kidney_P3_CapMes_Crym_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

CD248 EGFR CACHD1 NOTCH2

4.92e-04783114gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

CD248 EGFR NOTCH2

6.98e-04356113gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

CD248 EGFR NOTCH2

7.44e-04364113gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 KCP NOTCH3 DAGLA

4.62e-08157114bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR KCP NOTCH3

1.01e-07191114b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2|Control_saline / Treatment groups by lineage, cell group, cell type

CD248 NOTCH2 KCP NOTCH3

1.22e-07200114bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KCP NOTCH3 DAGLA

6.61e-061561136365b69ede98bc866e996bc52736b00401aacf6f
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD4 NOTCH2 C22orf42

6.87e-06158113551e3fd7cabc94ba933607ccdcf93f4e799be43a
ToppCellTCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-3|TCGA-Adrenal / Sample_Type by Project: Shred V9

CD248 NOTCH3 NOTCH4

7.27e-0616111352239a887799362256ecd7e740b716b88ed59a62
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)-M1_3|Striatum / BrainAtlas - Mouse McCarroll V32

THSD4 CD248 NOTCH3

7.68e-06164113e24b06a14565f7798ac50c2fe3f34d4547b9000e
ToppCellfacs-Heart-RV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR KCP

8.55e-06170113d7c9a604311974ff87ece43a0f8725a234d262f7
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NOTCH2 KCP NOTCH3

8.55e-061701135570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 NOTCH2 NOTCH3

8.70e-061711134ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 KCP NOTCH3

9.01e-061731133059325901b1e5e12a1a91183f14267288b2f600
ToppCellfacs-Lung-EPCAM-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 KCP NOTCH3

9.01e-0617311336c8338463ee4cc432f568728d55989360f9a68d
ToppCell10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

9.98e-0617911398c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCelldroplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.01e-05180113b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 KCP NOTCH3

1.07e-051831138a799807fbf24456a9811e0c64068187940a2f71
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 KCP NOTCH3

1.08e-05184113102b6f621a5b551e622f97b12d787c080b052a72
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 KCP NOTCH3

1.08e-05184113689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.08e-0518411394748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.08e-05184113819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CD248 KCP NOTCH3

1.08e-05184113327ff3ac8d2fecdd5d242bdc34f0dfdb1c59a68b
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.10e-0518511338486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.10e-051851133c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD248 KCP NOTCH3

1.14e-05187113fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD248 KCP NOTCH3

1.14e-05187113a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.16e-05188113d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD248 KCP NOTCH3

1.16e-05188113ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

CD248 KCP NOTCH3

1.17e-05189113d7ed96add29f219183c802895fbff519b627f635
ToppCelldroplet-Kidney-nan-3m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.17e-05189113a959c9d6a0866582688a4204d625c1e5a123e93d
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

CD248 NOTCH3 NOTCH4

1.17e-051891139c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD248 NOTCH3 DAGLA

1.17e-05189113ca3a04c202afc32aa11d17154066ef7dc6d01405
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THSD4 NOTCH2 NOTCH3

1.17e-0518911345e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 EGFR NOTCH2

1.19e-05190113048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 EGFR NOTCH2

1.19e-051901131121eb607a984c59fbffe7220837fc178745aa55
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

EGFR CACHD1 NOTCH4

1.19e-051901134f15842b424eefadbfe451875e517cf70e29607f
ToppCellE15.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD248 EGFR NOTCH3

1.19e-0519011384fbd5664ec886120963d4f50dfa1fd1851d36c1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 NOTCH2 NOTCH3

1.21e-0519111396ff4cfbdcaec4b8568f9482d732dddd399121d3
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.21e-051911138597a8af294f24496c317d995f07eb5dcc25c13c
ToppCellfacs-Aorta-Heart-18m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR NOTCH2

1.23e-051921136d4fe7ea278efa4b9d43f8a3c282bc0e0e9abaea
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR NOTCH2

1.23e-0519211347aed7c8e6f5ce1084821212a04f568319e65fd6
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR NOTCH2

1.23e-051921132c6406bc97c3224099b94a43f2890f057b528fa6
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

THSD4 EGFR CACHD1

1.23e-05192113efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellP03-Mesenchymal-developing_mesenchymal_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD248 NOTCH2 NOTCH3

1.23e-05192113063e119c4b58957643908f667e6cfd6f7517fd03
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.23e-051921133617d2bc7e33d981f3ec349e9962d8d4bd822fbd
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.25e-05193113cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.25e-05193113e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.25e-051931136ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 NOTCH2 NOTCH3

1.27e-051941133bff2e4eb16719ab7419b2f94c9c6e7302aa6629
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.27e-0519411380be44e9ddd9f6ddd9dff7cba0eb457431204c2d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.27e-05194113b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.27e-05194113bf34737ae2dc218f890fbb9201c308b324415749
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR NOTCH2

1.27e-05194113bc945450b350f597c3ff910d3a14a533d90086a8
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CD248 NOTCH3

1.27e-051941134ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 NOTCH2 NOTCH3

1.27e-05194113fdaf61cbe7f77ff5358d150b38adb1fe3778e961
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR CACHD1

1.31e-05196113b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD248 EGFR CACHD1

1.31e-05196113787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 CACHD1 NOTCH4

1.31e-05196113e224338490691d92c1f70b57112fabdcc92b06a9
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.33e-051971135afddde4e2b5cd55abe11e9b9efae02dbdc3da3a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 CACHD1 NOTCH4

1.33e-05197113c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma-adipo-CAR|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.33e-051971131baffd087ca194a7355fefbb3bf67befb14fe2de
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CD248 KCP NOTCH3

1.33e-0519711344cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 CD248 NOTCH3

1.33e-051971138c728cd3c0382c4f3e4b78647b6e1447bb40ace1
ToppCell10x3'2.3-week_17-19-Mesenchymal_adipo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.33e-05197113b9745e382baa2725dfcae060701fb53f6c8a31fa
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

THSD4 CD248 NOTCH3

1.33e-051971132872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 CACHD1 NOTCH4

1.33e-051971132844dbcd0a673ed81c99920aa45858651a00736d
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteochondral_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.33e-05197113c165c6fd12dc649b39e920d8528e2eb65c61956b
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

THSD4 CD248 NOTCH3

1.35e-05198113b258f672529fb2c03e62e2696d335043c4963280
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

THSD4 EGFR NOTCH3

1.35e-0519811355e583321f60c95898d93cd0d2615c6692db52ec
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CD248 KCP NOTCH3

1.35e-0519811376d46950c11cb4708866db0da54ce00d5c0adab8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD4 EGFR NOTCH2

1.35e-05198113a860246bcea847249a78fd2e86ed8e04371060db
ToppCellBronchial-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 EGFR CACHD1

1.37e-051991135f7da3eab58ace6cddb3179a415cd839d5767958
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 EGFR CACHD1

1.37e-05199113725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.37e-05199113251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

THSD4 EGFR NOTCH3

1.37e-05199113e19b296d583f8bad3b66ee998a8153634d6fe09e
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.37e-05199113117f4f43b6c06dda553799b1063e827bce697370
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors|1_mon / Sample Type, Dataset, Time_group, and Cell type.

CACHD1 NOTCH2 NOTCH3

1.37e-05199113358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCellNon-neuronal-Postmitotic-Endothelial|World / Primary Cells by Cluster

CD248 NOTCH3 NOTCH4

1.37e-05199113b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCell10x5'v1-week_14-16-Mesenchymal_adipo-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

CD248 EGFR NOTCH3

1.37e-051991139b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCellParenchymal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 EGFR CACHD1

1.37e-051991135cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell10x3'2.3-week_17-19-Mesenchymal_myocytic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

THSD4 EGFR NOTCH3

1.37e-05199113801887db51ac5dc5b068808ff75e3a46643398e9
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial|World / Primary Cells by Cluster

CD248 NOTCH3 NOTCH4

1.37e-051991139e01eee126247a0696c71b019f855a8a41a0ede3
ToppCellNon-neuronal-Postmitotic-Endothelial-Endothelial-24|World / Primary Cells by Cluster

CD248 NOTCH3 NOTCH4

1.37e-051991130b4edf3e359749827ef978a77b5267ddde732d71
ToppCelldistal-mesenchymal-Pericyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 KCP NOTCH3

1.37e-05199113000d9b5f5a48e56f0733390adb3d7270c49a4a1a
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-05200113cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

THSD4 EGFR NOTCH4

1.39e-0520011368fce28690246895fd33354b30960ebcc31aa4cc
ToppCellproximal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 KCP NOTCH3

1.39e-0520011398cbd0f4994e645f70c0bc5ebc1c3a3b28c6b67f
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-05200113b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

THSD4 EGFR NOTCH4

1.39e-05200113032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-0520011369edc375d85689300d1dbc1217fedc40063ecdcb
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 KCP NOTCH3

1.39e-05200113911db29f254bb697610e720ba78816e2c7f57933
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-05200113786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

THSD4 CD248 NOTCH3

1.39e-0520011367dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellproximal-mesenchymal-Pericyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CD248 KCP NOTCH3

1.39e-0520011303119a979bc912a98e6fc87addcbc25d8ecf2fb0
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-05200113b5b5a32925f225610fe25a021a742d6397162863
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-052001138c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

THSD4 EGFR NOTCH4

1.39e-05200113376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

THSD4 EGFR NOTCH4

1.39e-05200113878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

THSD4 EGFR NOTCH4

1.39e-052001137136936d05ab344a560cf159684c881063b5430d
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

THSD4 EGFR NOTCH4

1.39e-052001137fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-05200113cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CD248 KCP NOTCH3

1.39e-05200113d2fcd3bd7c3223875f027eeb48ff621192a5f242
DrugLinuron

EGFR NOTCH2 NOTCH3 NOTCH4

3.05e-07128114ctd:D008044
Drugprocymidone

EGFR NOTCH2 NOTCH3 NOTCH4

6.57e-07155114ctd:C035988
Druggamma-secretase inhibitor I

NOTCH2 NOTCH3

1.27e-064112CID011754711
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

THSD4 CD248 AGRP DAGLA

1.54e-061921145216_UP
DrugvgBE

NOTCH2 NOTCH3

3.18e-066112CID000193461
DrugMW167

NOTCH2 NOTCH3

4.45e-067112CID010312597
Drugprochloraz

EGFR NOTCH2 NOTCH3 NOTCH4

5.80e-06268114ctd:C045362
Druglead stearate

NOTCH2 NOTCH3 NOTCH4

7.82e-0684113CID000061258
Drugazoxystrobin

AGRP NOTCH2 NOTCH3

9.00e-0688113CID003034285
DrugDichlorodiphenyl Dichloroethylene

EGFR NOTCH2 NOTCH3 NOTCH4

9.31e-06302114ctd:D003633
Drugepoxiconazole

EGFR NOTCH2 NOTCH3 NOTCH4

1.50e-05341114ctd:C109476
Drug(3Z)-3-[3-(hydroxyamino)indolin-2-ylidene]oxindole

NOTCH2 NOTCH3

4.43e-0521112CID016073041
Drug1-piperidinocyclohexanecarbonitrile

NOTCH2 NOTCH3

6.33e-0525112CID000062529
DrugAC1NRAEN

NOTCH2 NOTCH3

9.16e-0530112CID005287841
Drug(S)-(-)-Atenolol [93379-54-5]; Up 200; 15uM; MCF7; HT_HG-U133A

THSD4 EGFR NOTCH2

9.70e-051951135325_UP
DrugNitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A

THSD4 EGFR AGRP

9.85e-051961136464_UP
DrugTrimethobenzamide hydrochloride [554-92-7]; Down 200; 9.4uM; PC3; HT_HG-U133A

THSD4 NOTCH3 DAGLA

9.85e-051961134100_DN
DrugAmikacin hydrate [37517-28-5]; Up 200; 6.6uM; PC3; HT_HG-U133A

AGRP NOTCH2 NOTCH3

9.85e-051961136715_UP
DrugCinnarizine [298-57-7]; Up 200; 10.8uM; MCF7; HT_HG-U133A

EGFR NOTCH2 DAGLA

1.00e-041971137174_UP
DrugSulfamethizole [144-82-1]; Up 200; 14.8uM; PC3; HT_HG-U133A

THSD4 EGFR AGRP

1.00e-041971135798_UP
DrugAC1L9NAZ

AGRP NOTCH2 NOTCH3

1.02e-04198113CID000449606
DrugLoracarbef [121961-22-6]; Up 200; 10.8uM; MCF7; HT_HG-U133A

CD248 AGRP DAGLA

1.02e-041981135492_UP
DrugDipyrone [5907-38-0]; Up 200; 12uM; HL60; HT_HG-U133A

EGFR NOTCH3 DAGLA

1.02e-041981132175_UP
DrugProxyphylline [603-00-9]; Up 200; 16.8uM; PC3; HT_HG-U133A

EGFR NOTCH3 DAGLA

1.03e-041991137290_UP
Drugfluorescein-5-maleimide

CD248 AGRP

1.04e-0432112CID000122038
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

EGFR AGRP DAGLA

1.05e-042001135601_UP
DrugPhenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A

EGFR AGRP DAGLA

1.05e-042001135991_UP
DrugCHAPSO

NOTCH2 NOTCH3

1.48e-0438112CID000122145
DrugAC1NRBNZ

NOTCH2 NOTCH3

3.46e-0458112CID005288543
Drug2-nitroisocitrate

NOTCH2 NOTCH3

3.95e-0462112CID000166578
DrugA25152

NOTCH2 NOTCH3

3.95e-0462112CID000002956
Drugpyrachlostrobin

CD248 EGFR NOTCH2 NOTCH3

4.32e-04811114ctd:C513428
DrugGDP-fucose

NOTCH2 NOTCH3

4.75e-0468112CID000000451
DrugR59949

EGFR DAGLA

5.03e-0470112CID000657356
DrugDale

NOTCH2 NOTCH3

5.18e-0471112CID005486816
DrugDeoxyglucose

EGFR AGRP

5.62e-0474112ctd:D003847
DrugThromstop

NOTCH3 NOTCH4

5.62e-0474112CID000004406
Drugrhamnose

EGFR NOTCH2 NOTCH3

5.70e-04356113CID000000840
DrugAndrogen Antagonists

NOTCH2 NOTCH4

5.78e-0475112ctd:D000726
DrugSureCN2313095

NOTCH2 NOTCH3

5.93e-0476112CID011840973
DrugAC1L9M2J

NOTCH2 NOTCH3

5.93e-0476112CID000448538
DrugAG213

EGFR DAGLA

8.12e-0489112CID005328803
DrugAtropine

EGFR NOTCH4

8.86e-0493112ctd:D001285
DiseaseSquamous cell carcinoma

EGFR NOTCH2 NOTCH3 NOTCH4

9.58e-08124114C0007137
Diseaseintestinal cancer (implicated_via_orthology)

EGFR NOTCH2 NOTCH3

1.90e-0732113DOID:10155 (implicated_via_orthology)
DiseaseSkin Neoplasms

NOTCH2 NOTCH3 NOTCH4

1.24e-0659113C0037286
DiseaseMalignant neoplasm of skin

NOTCH2 NOTCH3 NOTCH4

1.24e-0659113C0007114
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH2 NOTCH3

2.65e-067112DOID:3620 (implicated_via_orthology)
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH2 NOTCH3

2.65e-067112DOID:299 (implicated_via_orthology)
DiseaseGlioblastoma

EGFR NOTCH2 NOTCH3

3.00e-0679113C0017636
DiseaseGiant Cell Glioblastoma

EGFR NOTCH2 NOTCH3

3.61e-0684113C0334588
DiseaseSquamous cell carcinoma of esophagus

EGFR NOTCH2 NOTCH3

5.24e-0695113C0279626
DiseaseGlioblastoma Multiforme

EGFR NOTCH2 NOTCH3

8.36e-06111113C1621958
DiseaseMammary Neoplasms, Human

EGFR NOTCH2 NOTCH3 NOTCH4

2.96e-05525114C1257931
DiseaseMammary Carcinoma, Human

EGFR NOTCH2 NOTCH3 NOTCH4

2.96e-05525114C4704874
DiseaseMammary Neoplasms

EGFR NOTCH2 NOTCH3 NOTCH4

3.00e-05527114C1458155
DiseaseBreast Carcinoma

EGFR NOTCH2 NOTCH3 NOTCH4

3.26e-05538114C0678222
DiseaseCarcinoma, Pancreatic Ductal

NOTCH3 NOTCH4

3.47e-0524112C0887833
Diseasebrain cancer (implicated_via_orthology)

NOTCH2 NOTCH3

4.09e-0526112DOID:1319 (implicated_via_orthology)
Diseasealcohol use disorder (implicated_via_orthology)

EGFR NOTCH2 NOTCH3

4.51e-05195113DOID:1574 (implicated_via_orthology)
Diseasecolorectal cancer (implicated_via_orthology)

NOTCH2 NOTCH3

5.46e-0530112DOID:9256 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

NOTCH2 NOTCH3 NOTCH4

6.03e-05215113DOID:9970 (implicated_via_orthology)
Diseasecervical cancer

EGFR NOTCH2

7.04e-0534112C4048328
DiseaseUterine Cervical Neoplasm

EGFR NOTCH2

7.47e-0535112C0007873
DiseaseLung Neoplasms

EGFR NOTCH2 NOTCH3

1.12e-04265113C0024121
DiseaseMalignant neoplasm of lung

EGFR NOTCH2 NOTCH3

1.13e-04266113C0242379
Diseasecancer (implicated_via_orthology)

NOTCH2 NOTCH3 NOTCH4

1.16e-04268113DOID:162 (implicated_via_orthology)
Diseasecholesteryl ester 20:4 measurement

EGFR DAGLA

1.19e-0444112EFO_0010348
Diseasecholesteryl ester 20:5 measurement

EGFR DAGLA

1.19e-0444112EFO_0010349
Diseasesystemic scleroderma

KCP NOTCH4

4.44e-0485112EFO_0000717
DiseaseMalignant neoplasm of breast

EGFR NOTCH2 NOTCH3 NOTCH4

4.69e-041074114C0006142
DiseaseOral ulcer

KCP NOTCH4

7.01e-04107112HP_0000155
DiseaseC-reactive protein measurement

CD248 CACHD1 KCP DAGLA

7.27e-041206114EFO_0004458
DiseaseBladder Neoplasm

EGFR NOTCH2

1.20e-03140112C0005695
DiseaseMalignant neoplasm of urinary bladder

EGFR NOTCH2

1.21e-03141112C0005684
DiseaseNon-Small Cell Lung Carcinoma

EGFR NOTCH3

1.48e-03156112C0007131
Diseaseeosinophil count

CACHD1 NOTCH2 KCP NOTCH4

1.60e-031488114EFO_0004842
DiseaseNeoplasm Invasiveness

EGFR NOTCH2

2.05e-03184112C0027626
Diseaselinoleic acid measurement

C22orf42 DAGLA

2.09e-03186112EFO_0006807

Protein segments in the cluster

PeptideGeneStartEntry
HESCLGQQVPCCDPC

AGRP

91

O00253
CEDPCAQAPCEQQCE

CD248

271

Q9HCU0
CHRMEQNECECPCEC

CACHD1

961

Q5VU97
QNECECPCECPLEVN

CACHD1

966

Q5VU97
NCDCCRPDVGPCHEC

C22orf42

16

Q6IC83
LCEENIDNCDPDPCH

NOTCH2

566

Q04721
CDQDINDCDPNPCLN

NOTCH3

846

Q9UM47
CEQEVDPCLAQPCQH

NOTCH3

1081

Q9UM47
ENSECIQCHPECLPQ

EGFR

551

P00533
NHPAEQCCCCEQEEP

DAGLA

611

Q9Y4D2
CQECRCQEGHAHCQP

KCP

566

Q6ZWJ8
RQGPHDCCPQCSDCE

KCP

1006

Q6ZWJ8
PDCEVNPDNCVSHQC

NOTCH4

271

Q99466
SCNPQDCVPEVDENC

THSD4

961

Q6ZMP0