Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	4.11e-08	11	199	5	GO:0004523
GeneOntologyMolecularFunction	endonuclease activity	ERVK-6 PNKP ERVK-7 ERVK-10 PXDNL ERVK-11 PIWIL4 ERN2 APLF ERVK-8 ALKBH3	1.20e-07	136	199	11	GO:0004519
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	1.74e-07	14	199	5	GO:0003964
GeneOntologyMolecularFunction	hydrolase activity, acting on ester bonds	ERVK-6 PLB1 PNKP ERVK-7 ERVK-10 ADPRM PTPRG PXDNL GNAS ERVK-11 AOAH LIPF PIWIL4 CTDSP1 ACOT6 ERN2 APLF FICD G6PC3 ERVK-8 HELZ2 ALKBH3 SSH2 TDP1 TNS1	5.07e-07	807	199	25	GO:0016788
GeneOntologyMolecularFunction	nuclease activity	ERVK-6 PNKP ERVK-7 ERVK-10 PXDNL ERVK-11 PIWIL4 ERN2 APLF ERVK-8 HELZ2 ALKBH3 TDP1	5.88e-07	231	199	13	GO:0004518
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	1.67e-06	21	199	5	GO:0035613
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 PIWIL4 ERN2 ERVK-8	1.39e-05	79	199	7	GO:0004521
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	3.14e-05	37	199	5	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	3.59e-05	38	199	5	GO:0034061
GeneOntologyMolecularFunction	RNA nuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 PIWIL4 ERN2 ERVK-8 HELZ2	6.70e-05	136	199	8	GO:0004540
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	9.20e-05	46	199	5	GO:0016893
GeneOntologyMolecularFunction	tripeptidyl-peptidase activity	TPP2 TPP1	2.95e-04	3	199	2	GO:0008240
GeneOntologyMolecularFunction	peptidase activity	LVRN PCSK1 TPP2 ERVK-6 USP9X ERVK-7 ERVK-10 GGT7 TPP1 KLK5 FOLH1 PRSS56 NUP98 AGBL3 ADAMTS6 ERVK-8 PCSK4	3.10e-04	654	199	17	GO:0008233
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	4.89e-04	37	199	4	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.42e-04	38	199	4	GO:0070001
GeneOntologyMolecularFunction	procollagen galactosyltransferase activity	COLGALT2 CERCAM	5.85e-04	4	199	2	GO:0050211
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-11 FICD ERVK-8 TNKS2	8.41e-04	152	199	7	GO:0016779
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM2 GAA	9.69e-04	5	199	2	GO:0004558
GeneOntologyMolecularFunction	phospholipid binding	MAP1B SPTBN2 NUP62 SNX13 VNN1 TPP1 PHF12 APOB ARHGAP35 MREG EXOC1 VPS13B ARHGAP33 PSD4	1.24e-03	548	199	14	GO:0005543
GeneOntologyMolecularFunction	endopeptidase activity	PCSK1 TPP2 ERVK-6 USP9X ERVK-7 ERVK-10 TPP1 KLK5 PRSS56 ADAMTS6 ERVK-8 PCSK4	1.32e-03	430	199	12	GO:0004175
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	8.91e-08	13	196	5	GO:0015074
GeneOntologyBiologicalProcess	RNA-templated DNA biosynthetic process	ERVK-6 PNKP ATR ERVK-7 ERVK-10 ERVK-11 ERVK-8 TNKS2	1.24e-06	83	196	8	GO:0006278
GeneOntologyBiologicalProcess	postsynapse organization	KIF1A MAP1B MYO9A USP9X SPTBN2 DGKB ITGA3 CSMD2 SYNGAP1 NLGN4X PRICKLE1 PPFIA2 ARHGAP33	9.93e-06	313	196	13	GO:0099173
GeneOntologyBiologicalProcess	postsynapse assembly	MAP1B USP9X SPTBN2 CSMD2 NLGN4X PRICKLE1 ARHGAP33	2.99e-05	93	196	7	GO:0099068
GeneOntologyBiologicalProcess	DNA-templated DNA replication	ERVK-6 PNKP ATR ERVK-7 ERVK-10 ERVK-11 DONSON ORC2 ERVK-8	5.32e-05	178	196	9	GO:0006261
GeneOntologyBiologicalProcess	DNA synthesis involved in DNA repair	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	9.05e-05	48	196	5	GO:0000731
Domain	-	PCSK1 TPP2 TPP1 PCSK4	3.17e-06	11	189	4	3.40.50.200
Domain	Peptidase_S8/S53_dom	PCSK1 TPP2 TPP1 PCSK4	3.17e-06	11	189	4	IPR000209
Domain	Peptidase_S8	PCSK1 TPP2 TPP1 PCSK4	3.17e-06	11	189	4	PF00082
Domain	-	PNKP KIF1A STARD9 PHF12 APLF	2.94e-05	36	189	5	2.60.200.20
Domain	FHA_dom	PNKP KIF1A STARD9 PHF12 APLF	2.94e-05	36	189	5	IPR000253
Domain	ARM-type_fold	ATR DOCK11 NBEAL1 USP9X CUL9 LYST PIK3CA ZNFX1 APOB UPF2 INF2 IPO13 PPP6R3	4.34e-05	339	189	13	IPR016024
Domain	Peptidase_S8_His-AS	PCSK1 TPP2 PCSK4	8.19e-05	9	189	3	IPR022398
Domain	Peptidase_S8_Ser-AS	PCSK1 TPP2 PCSK4	8.19e-05	9	189	3	IPR023828
Domain	WD40	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SEC31A DENND3 TLE6	9.33e-05	268	189	11	SM00320
Domain	WD40_repeat	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SEC31A DENND3 TLE6	1.06e-04	272	189	11	IPR001680
Domain	Peptidase_S8_subtilisin-rel	PCSK1 TPP2 PCSK4	1.16e-04	10	189	3	IPR015500
Domain	SUBTILASE_ASP	PCSK1 TPP2 PCSK4	1.16e-04	10	189	3	PS00136
Domain	SUBTILASE_HIS	PCSK1 TPP2 PCSK4	1.16e-04	10	189	3	PS00137
Domain	SUBTILASE_SER	PCSK1 TPP2 PCSK4	1.16e-04	10	189	3	PS00138
Domain	WD_REPEATS_1	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SEC31A DENND3 TLE6	1.29e-04	278	189	11	PS00678
Domain	WD_REPEATS_2	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SEC31A DENND3 TLE6	1.33e-04	279	189	11	PS50082
Domain	WD_REPEATS_REGION	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SEC31A DENND3 TLE6	1.33e-04	279	189	11	PS50294
Domain	-	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SELENBP1 SEC31A DENND3 TLE6	1.54e-04	333	189	12	2.130.10.10
Domain	WD40/YVTN_repeat-like_dom	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SELENBP1 SEC31A DENND3 TLE6	1.63e-04	335	189	12	IPR015943
Domain	SMAD_FHA_domain	PNKP KIF1A STARD9 PHF12 APLF	1.78e-04	52	189	5	IPR008984
Domain	WD40_repeat_dom	PPP2R2D TBL1Y NBEAL1 WDR33 LYST TECPR2 WDR24 TBL1X SEC31A DENND3 TLE6	2.29e-04	297	189	11	IPR017986
Domain	Glyco_transf_25	COLGALT2 CERCAM	3.04e-04	3	189	2	PF01755
Domain	-	DGKB DGKG	3.04e-04	3	189	2	1.10.238.110
Domain	Glyco_trans_25	COLGALT2 CERCAM	3.04e-04	3	189	2	IPR002654
Domain	DAG_kinase_N	DGKB DGKG	3.04e-04	3	189	2	PF14513
Domain	DAG_kinase_typeI_N	DGKB DGKG	3.04e-04	3	189	2	IPR029477
Domain	WD40	PPP2R2D TBL1Y NBEAL1 WDR33 LYST WDR24 TBL1X SEC31A DENND3 TLE6	3.17e-04	259	189	10	PF00400
Domain	Gal_mutarotase_N	MGAM2 GAA	6.03e-04	4	189	2	IPR031727
Domain	NtCtMGAM_N	MGAM2 GAA	6.03e-04	4	189	2	PF16863
Domain	Propept_inh	PCSK1 TPP1 PCSK4	6.25e-04	17	189	3	IPR009020
Domain	SAM_2	ANKS1A PPFIBP2 PPFIA2 TNKS2	9.21e-04	43	189	4	PF07647
Domain	Lipase_GDSL	PLB1 AOAH	9.98e-04	5	189	2	PF00657
Domain	GDSL	PLB1 AOAH	9.98e-04	5	189	2	IPR001087
Domain	LIPASE_GDSL_SER	PLB1 AOAH	9.98e-04	5	189	2	PS01098
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	7.46e-07	4	200	3	10469592
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TPP2 HECW1 DOCK11 TBL1Y USP9X SPTBN2 MPDZ SYNGAP1 ZNF462 STOX2 TBL1X ANKS1A MAPK8IP1 KIF23 HCN3 ZNFX1 SEC31A CCDC88C SSH2 TNS1	8.54e-07	963	200	20	28671696
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	WDR33 MPDZ NHLRC2 PCDH17 GGT7 MIEF1 ANKS1A KIF23 SUN1 MFSD9 RNF213 NCOA4 ZC3H7A ATAD1 GUSB MASTL	6.02e-06	733	200	16	34672954
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	SPTBN2 ITGA3 NLGN4X PTPRG PIK3CA PPFIBP2 CTDSP1 APOB CDCP1 TMEM87A MAPK13 VPS13B PSD4	2.87e-05	569	200	13	30639242
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	PPP2R2D BAHCC1 PHF12 HCN3 CCDC88C CERCAM	3.02e-05	103	200	6	10819331
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HECW1 SPTBN2 ZNF462 PRUNE2 RNF213 ENPP4 ARHGAP35 DENND3 CCDC88C HELZ2 SSH2 UNC80	3.18e-05	493	200	12	15368895
Pubmed	Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models.	BCL2L1 PIK3CA	3.29e-05	2	200	2	23475955
Pubmed	The sodium leak channel, NALCN, in health and disease.	NALCN UNC80	3.29e-05	2	200	2	24904279
Pubmed	Microtubule-associated protein 1B: a neuronal binding partner for gigaxonin.	MAP1B GAN	3.29e-05	2	200	2	12147674
Pubmed	X-linked late-onset sensorineural deafness caused by a deletion involving OA1 and a novel gene containing WD-40 repeats.	TBL1Y TBL1X	3.29e-05	2	200	2	10330347
Pubmed	Erythropoietin promotes survival of primary human endothelial cells through PI3K-dependent, NF-kappaB-independent upregulation of Bcl-xL.	BCL2L1 PIK3CA	3.29e-05	2	200	2	17237249
Pubmed	UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN.	NALCN UNC80	3.29e-05	2	200	2	26545877
Pubmed	DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction.	MPDZ CCDC88C	3.29e-05	2	200	2	31268831
Pubmed	Peptide neurotransmitters activate a cation channel complex of NALCN and UNC-80.	NALCN UNC80	3.29e-05	2	200	2	19092807
Pubmed	Characterization of murine middle repetitive DNA.	HPD GUSB	3.29e-05	2	200	2	7684230
Pubmed	Molecular signatures of disease brain endothelia provide new sites for CNS-directed enzyme therapy.	TPP1 GUSB	3.29e-05	2	200	2	19749771
Pubmed	RGS-PX1, a GAP for GalphaS and sorting nexin in vesicular trafficking.	SNX13 GNAS	3.29e-05	2	200	2	11729322
Pubmed	Transducin β-like 1, X-linked and nuclear receptor co-repressor cooperatively augment the ligand-independent stimulation of TRH and TSHβ gene promoters by thyroid hormone receptors.	TBL1Y TBL1X	3.29e-05	2	200	2	29794369
Pubmed	Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions.	ATR BCL2L1 PIK3CA PIM1 MAPK8IP1 SEC31A ARFGAP2 SLC16A5 DEPDC5	3.45e-05	276	200	9	28319085
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	KIF1A SYNGAP1 STOX2 PIK3CA PPFIA2 AFAP1 EXOC1 ARHGAP33	4.12e-05	218	200	8	33378226
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	MAP1B DOCK11 MYO9A MPDZ NUP62 LYST STOX2 STARD9 MIEF1 GNAS ANKS1A KIF23 CCDC88C ARFGAP2 GAN SSH2	4.27e-05	861	200	16	36931259
Pubmed	Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.	TPP2 PNKP USP9X STK11IP TPP1 KIF23 NUP98 INF2	5.32e-05	226	200	8	37839992
Pubmed	Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.	NALCN UNC80	9.83e-05	3	200	2	26708753
Pubmed	NUP98-BPTF promotes oncogenic transformation through PIM1 upregulation.	PIM1 NUP98	9.83e-05	3	200	2	38940430
Pubmed	Tbl1 promotes Wnt-β-catenin signaling-induced degradation of the Tcf7l1 protein in mouse embryonic stem cells.	TBL1Y TBL1X	9.83e-05	3	200	2	38639717
Pubmed	Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).	NALCN UNC80	9.83e-05	3	200	2	30167850
Pubmed	The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis.	PIK3CA FGFR2	9.83e-05	3	200	2	27348297
Pubmed	Transducin β-like protein 1 recruits nuclear factor κB to the target gene promoter for transcriptional activation.	TBL1Y TBL1X	9.83e-05	3	200	2	21189284
Pubmed	The downregulation of Mcl-1 via USP9X inhibition sensitizes solid tumors to Bcl-xl inhibition.	USP9X BCL2L1	9.83e-05	3	200	2	23171055
Pubmed	Neurological disorders associated with DNA strand-break processing enzymes.	PNKP TDP1	9.83e-05	3	200	2	27470939
Pubmed	The Proto-oncogene PKCι regulates the alternative splicing of Bcl-x pre-mRNA.	BCL2L1 PIK3CA	9.83e-05	3	200	2	22522453
Pubmed	Activation of a non-genomic Pim-1/Bad-Pser75 module is required for an efficient pro-survival effect of Bcl-xL induced by androgen in LNCaP cells.	BCL2L1 PIM1	9.83e-05	3	200	2	21187157
Pubmed	Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.	ERVK-6 ERVK-11	9.83e-05	3	200	2	9971820
Pubmed	Expression of the T-box gene Eomesodermin during early mouse development.	FGFR2 TBR1	9.83e-05	3	200	2	10330500
Pubmed	Specific recognition of a multiply phosphorylated motif in the DNA repair scaffold XRCC1 by the FHA domain of human PNK.	PNKP APLF	9.83e-05	3	200	2	19155274
Pubmed	Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.	NALCN UNC80	9.83e-05	3	200	2	21040849
Pubmed	Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.	NALCN UNC80	9.83e-05	3	200	2	32620897
Pubmed	USP9x-mediated deubiquitination of EFA6 regulates de novo tight junction assembly.	USP9X PSD4	9.83e-05	3	200	2	20339350
Pubmed	Decreased expression of NMDA receptor-associated proteins in frontal cortex of elderly patients with schizophrenia.	MPDZ SYNGAP1	9.83e-05	3	200	2	19483657
Pubmed	High-throughput mutation profiling of primary and metastatic endometrial cancers identifies KRAS, FGFR2 and PIK3CA to be frequently mutated.	PIK3CA FGFR2	9.83e-05	3	200	2	23300780
Pubmed	HECW1 induces NCOA4-regulated ferroptosis in glioma through the ubiquitination and degradation of ZNF350.	HECW1 NCOA4	9.83e-05	3	200	2	38049396
Pubmed	UNC80 functions as a scaffold for Src kinases in NALCN channel function.	NALCN UNC80	9.83e-05	3	200	2	19535918
Pubmed	TPP1 Blocks an ATR-Mediated Resection Mechanism at Telomeres.	ATR TPP1	9.83e-05	3	200	2	26778124
Pubmed	Mutant Tbl1x male mice have a short life span and do not breed: unexpected findings.	TBL1Y TBL1X	9.83e-05	3	200	2	38381448
Pubmed	Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study.	FOLH1 SHMT1	9.83e-05	3	200	2	15122597
Pubmed	Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways.	NUP62 NUP98	9.83e-05	3	200	2	22334672
Pubmed	Ocular albinism with infertility and late-onset sensorineural hearing loss.	TBL1X GPR143	9.83e-05	3	200	2	30160833
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	HECW1 NUP62 CNTROB SYNGAP1 SPARCL1 PHF12 PPFIA2 CTDSP1 SEC31A IPO13 TBR1 RASSF4	1.07e-04	560	200	12	21653829
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KIF1A MAP1B MYO9A ZNF462 PTPRG TECPR2 GNAS ADGRD1 TBL1X ANKS1A PRUNE2 SRD5A3 FOLH1 PPFIBP2 PPFIA2 RNF213 ARHGAP35 SELENON ARPC5 INF2 VPS13B	1.48e-04	1489	200	21	28611215
Pubmed	Feto-maternal cholesterol transport regulated by β-Klotho-FGF15 axis is essential for fetal growth.	FGFR2 KLB APOB	1.70e-04	19	200	3	37541847
Pubmed	Genome-wide association study evaluating lipoprotein-associated phospholipase A2 mass and activity at baseline and after rosuvastatin therapy.	NOX5 RNF213 APOB	1.70e-04	19	200	3	23118302
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	KIF1A STK11IP LYST RINT1 WDR24 SUN1 TMEM87A NDC1 TYW1B INF2 VPS13B	1.77e-04	504	200	11	34432599
Pubmed	SynGAP-MUPP1-CaMKII synaptic complexes regulate p38 MAP kinase activity and NMDA receptor-dependent synaptic AMPA receptor potentiation.	MPDZ SYNGAP1	1.96e-04	4	200	2	15312654
Pubmed	Cortical and thalamic axon pathfinding defects in Tbr1, Gbx2, and Pax6 mutant mice: evidence that cortical and thalamic axons interact and guide each other.	MPDZ TBR1	1.96e-04	4	200	2	11967891
Pubmed	Seizures are regulated by ubiquitin-specific peptidase 9 X-linked (USP9X), a de-ubiquitinase.	USP9X PRICKLE1	1.96e-04	4	200	2	25763846
Pubmed	Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.	PCSK1 PCSK4	1.96e-04	4	200	2	10701998
Pubmed	Loss of MIEF1/MiD51 confers susceptibility to BAX-mediated cell death and PINK1-PRKN-dependent mitophagy.	BCL2L1 MIEF1	1.96e-04	4	200	2	30894073
Pubmed	The structural gene for F liver protein (Flp) maps to chromosome 5 of the mouse.	HPD GUSB	1.96e-04	4	200	2	3478306
Pubmed	Pax6 regulation of Sox9 in the mouse retinal pigmented epithelium controls its timely differentiation and choroid vasculature development.	ANGPTL4 CDH5	1.96e-04	4	200	2	29986868
Pubmed	Effects of the JAK2 inhibitor, AZ960, on Pim/BAD/BCL-xL survival signaling in the human JAK2 V617F cell line SET-2.	BCL2L1 PIM1	1.96e-04	4	200	2	18775810
Pubmed	Karyopherin-centric control of nuclear pores based on molecular occupancy and kinetic analysis of multivalent binding with FG nucleoporins.	NUP62 NUP98	1.96e-04	4	200	2	24739174
Pubmed	Nup93, a vertebrate homologue of yeast Nic96p, forms a complex with a novel 205-kDa protein and is required for correct nuclear pore assembly.	NUP62 NUP98	1.96e-04	4	200	2	9348540
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10	1.96e-04	4	200	2	7983737
Pubmed	Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.	NUP62 NUP98	1.96e-04	4	200	2	30543681
Pubmed	FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features.	PIK3CA FGFR2	1.96e-04	4	200	2	22383975
Pubmed	Transcriptional co-factor Transducin beta-like (TBL) 1 acts as a checkpoint in pancreatic cancer malignancy.	TBL1Y TBL1X	1.96e-04	4	200	2	26070712
Pubmed	The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.	NALCN UNC80	1.96e-04	4	200	2	32494638
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-11 ERVK-8	2.17e-04	94	200	5	21542922
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	MAP1B USP9X STOX2 KLHDC3 MASTL FAM199X RASSF4 RIOK2 VPS13B PPP6R3	2.18e-04	432	200	10	23455922
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	CUL9 ITGA3 STK11IP CNTROB LYST GGT7 FGFR2 WDR24 BAHCC1 PHF12 ARHGAP35 CCDC88C SLC16A5 INF2 HELZ2 DEPDC5 ARHGAP33	2.40e-04	1105	200	17	35748872
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPP2 MAP1B MYO9A USP9X SPTBN2 DGKB ECI1 SYNGAP1 MAPK8IP1 SELENBP1 PPFIA2 ZNFX1 ARHGAP35 ARPC5 AFAP1 UPF2 INF2 EXOC1 SSH2 TNS1	2.40e-04	1431	200	20	37142655
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	TPP2 PNKP MAP1B SPTBN2 NUP62 RINT1 GNAS KIF23 RNF213 ABCF2 ARPC5 AKTIP AFAP1 NDC1 ATAD1 INF2 GUSB IPO13 EXOC1 PPP6R3	2.61e-04	1440	200	20	30833792
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PPP2R2D STOX2 TECPR2 ANKS1A CASP8AP2 PHF12 SUN1 AFAP1 IPO13 DEPDC5 PPP6R3	2.68e-04	529	200	11	14621295
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DGKB SNX13 SUPT7L SUN1 IPO13	3.03e-04	101	200	5	9872452
Pubmed	An unappreciated role for RNA surveillance.	LYST SNX13 DONSON TSPAN32 PRDM7	3.17e-04	102	200	5	14759258
Pubmed	Genomic profiling in a homogeneous molecular subtype of non-small cell lung cancer: An effort to explore new drug targets.	PIK3CA FGFR2	3.25e-04	5	200	2	26853422
Pubmed	Biosynthesis of alkyl lysophosphatidic acid by diacylglycerol kinases.	DGKB DGKG	3.25e-04	5	200	2	22627129
Pubmed	Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis.	ATR TPP1	3.25e-04	5	200	2	17948054
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7	3.25e-04	5	200	2	12629516
Pubmed	FGF21 signalling pathway and metabolic traits - genetic association analysis.	FGFR2 KLB	3.25e-04	5	200	2	20717167
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	3.25e-04	5	200	2	11401426
Pubmed	Pim kinases phosphorylate multiple sites on Bad and promote 14-3-3 binding and dissociation from Bcl-XL.	BCL2L1 PIM1	3.25e-04	5	200	2	16403219
Pubmed	Antagonism of VEGF-A-induced increase in vascular permeability by an integrin α3β1-Shp-1-cAMP/PKA pathway.	ITGA3 CDH5	3.25e-04	5	200	2	23074279
Pubmed	Oxidative stress inhibits nuclear protein export by multiple mechanisms that target FG nucleoporins and Crm1.	NUP62 NUP98	3.25e-04	5	200	2	19828735
Pubmed	The gamma phosphorylase kinase gene, Phkg, maps to mouse chromosome 5 near Gus.	HPD GUSB	3.25e-04	5	200	2	8111123
Pubmed	IL-3 induces a Pim1-dependent antiapoptotic pathway in primary human basophils.	BCL2L1 PIM1	3.25e-04	5	200	2	18768389
Pubmed	PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer.	PIK3CA FOLH1	3.25e-04	5	200	2	28292957
Pubmed	Dynein Light Chain 1 (DYNLT1) Interacts with Normal and Oncogenic Nucleoporins.	NUP62 NUP98	3.25e-04	5	200	2	23840580
Pubmed	Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.	TBL1Y TBL1X	3.25e-04	5	200	2	21459324
Pubmed	Characterization of Vps13b-mutant mice reveals neuroanatomical and behavioral phenotypes with females less affected.	TBR1 VPS13B	3.25e-04	5	200	2	37573958
Pubmed	Laminin-5-integrin interaction signals through PI 3-kinase and Rac1b to promote assembly of adherens junctions in HT-29 cells.	ITGA3 PIK3CA	3.25e-04	5	200	2	16339173
Pubmed	Distinct roles of c-Jun N-terminal kinase isoforms in neurite initiation and elongation during axonal regeneration.	MAP1B MAPK8IP1	3.25e-04	5	200	2	20534829
Pubmed	Exchange Factor TBL1 and Arginine Methyltransferase PRMT6 Cooperate in Protecting G Protein Pathway Suppressor 2 (GPS2) from Proteasomal Degradation.	TBL1Y TBL1X	3.25e-04	5	200	2	26070566
Pubmed	Mutations in tap uncouple RNA export activity from translocation through the nuclear pore complex.	NUP62 NUP98	3.25e-04	5	200	2	16314397
Pubmed	Regulated degradation of replication-dependent histone mRNAs requires both ATR and Upf1.	ATR UPF2	3.25e-04	5	200	2	16086026
Pubmed	The new enzymology of precursor processing endoproteases.	PCSK1 PCSK4	3.25e-04	5	200	2	1429684
Pubmed	A unique FGF23 with the ability to activate FGFR signaling through both αKlotho and βKlotho.	FGFR2 KLB	3.25e-04	5	200	2	22370560
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	HECW1 MAP1B USP9X DGKG ECI1 GGT7 SYNGAP1 SPARCL1 MAPK8IP1 PPFIA2 SUN1 ZNFX1 ARHGAP35 SLC6A11 ARFGAP2 ATAD1 EXOC1	3.40e-04	1139	200	17	36417873
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	HECW1 ZNF462 PRUNE2 CASP8AP2 ARHGAP35 HELZ2 UNC80	3.44e-04	225	200	7	12168954
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	PNKP ATR USP9X PPP6R3	3.53e-04	58	200	4	31067491
Cytoband	2q35	STK11IP CFAP65 CTDSP1 MREG UNC80	2.59e-05	79	200	5	2q35
Cytoband	Ensembl 112 genes in cytogenetic band chr2q35	STK11IP CFAP65 CTDSP1 MREG TNS1	2.65e-04	129	200	5	chr2q35
GeneFamily	WD repeat domain containing	PPP2R2D TBL1Y NBEAL1 WDR33 LYST WDR24 TBL1X SEC31A DENND3 TLE6	1.52e-05	262	126	10	362
GeneFamily	Nucleoporins	NUP62 NUP98 NDC1	1.41e-03	32	126	3	1051
GeneFamily	WD repeat domain containing\|BEACH domain containing	NBEAL1 LYST	1.68e-03	9	126	2	1230
GeneFamily	Proprotein convertase subtilisin/kexin family	PCSK1 PCSK4	1.68e-03	9	126	2	973
GeneFamily	EF-hand domain containing\|Diacylglycerol kinases	DGKB DGKG	2.09e-03	10	126	2	1178
GeneFamily	UPF1 like RNA helicases	ZNFX1 HELZ2	2.54e-03	11	126	2	1169
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_INTERM_NEUROENDOCRINE_CELL	PCSK1 KIF1A MAP1B SPTBN2 LYST PCDH17 CFAP65 PRUNE2 MAPK8IP1 COL12A1 CDCP1	5.24e-06	268	193	11	M45696
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A COLGALT2 FGFR2 GAL3ST1 FOLH1 ENPP4 INF2 IPO13 CERCAM	2.00e-07	194	195	9	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5\|TCGA-Pancreas / Sample_Type by Project: Shred V9	SPTBN2 BCL2L1 CDCA4 KIF23 CDCP1 SLC16A5 ANGPTL4 GAN	1.03e-06	174	195	8	73e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	MAP1B DGKB DGKG PXDNL SPARCL1 PRUNE2 PPFIA2 TNS1	1.33e-06	180	195	8	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAP1B COLGALT2 NLGN4X PXDNL SPARCL1 ADGRD1 COL12A1 PRICKLE1	1.64e-06	185	195	8	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COLGALT2 STOX2 STARD9 SPARCL1 ADGRD1 VWA3A ADAMTS6 UNC80	1.64e-06	185	195	8	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	MAP1B DGKB DGKG PTPRG SPARCL1 PRUNE2 COL12A1 PPFIA2	1.77e-06	187	195	8	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	ILEUM-non-inflamed-(8)_Activated_fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	MPDZ ZNF462 NLGN4X SLC49A3 MAPK8IP1 KIF23 COL12A1 ANGPTL4	2.00e-06	190	195	8	39fa110d19c97c7cac99f5fb91b26bc08e2f3b42
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B NBEAL1 DGKG STARD9 SPARCL1 ADGRD1 COL12A1 PPFIA2	2.08e-06	191	195	8	04c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 KIF1A MAP1B USP9X GNAS SEC31A UNC80 GAA	2.16e-06	192	195	8	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAP1B DGKB STARD9 SPARCL1 PRUNE2 PPFIA2 ADAMTS6 TNS1	2.61e-06	197	195	8	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAP1B DGKB DGKG STARD9 SPARCL1 PRUNE2 ADAMTS6 TNS1	2.71e-06	198	195	8	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 DGKB PTPRG VWA3A COL12A1 PPFIA2 UNC80	6.87e-06	160	195	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	wk_08-11-Hematologic-Meg-ery-Platelet\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	BCL2L1 ITGAX PIM1 TSPAN32 CD226 SPATA16 TRIM40	6.87e-06	160	195	7	e0591f95f3f47ffbe013ebbebf6bed8c7c344732
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PLB1 DGKB PTPRG VWA3A COL12A1 PPFIA2 UNC80	6.87e-06	160	195	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BCL2L1 PCDH17 TRNAU1AP SPARCL1 GPR143 HELZ2 CDH5	9.46e-06	168	195	7	55c9de7b3a1d6cf7b02b020ff92ab4ede8d195cc
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	MAP1B DGKB DGKG SPARCL1 PRUNE2 PPFIA2 SLC6A11	1.14e-05	173	195	7	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-ectodermal/neuroectodermal-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	PPCDC HPD UBXN10 SHMT1 AGBL3 SLC6A11 MAPK13	1.14e-05	173	195	7	7e4a2f5f92fbed16406bd097c0119278e4053245
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 KIF1A SPTBN2 CSMD2 PPFIA2 PCSK4 UNC80	1.23e-05	175	195	7	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK1 KIF1A SPTBN2 CSMD2 PPFIA2 PCSK4 UNC80	1.23e-05	175	195	7	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	droplet-Mammary_Gland-nan-21m-Endothelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDH17 ME3 BAHCC1 APLF DENND3 CDH5 ARHGAP33	1.28e-05	176	195	7	27e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 MYO9A ZNF462 STOX2 TBL1X PRUNE2 CERCAM	1.28e-05	176	195	7	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B DGKG COLGALT2 PCDH17 SPARCL1 PPFIA2 TNS1	1.33e-05	177	195	7	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B DGKG COLGALT2 PCDH17 SPARCL1 PPFIA2 TNS1	1.33e-05	177	195	7	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KIF1A DGKB PCDH17 NLGN4X PRSS56 SLC6A11 UNC80	1.43e-05	179	195	7	df6d2cdc4e204ce1a4628dc71dfbc5e6c6309b2a
ToppCell	facs-Marrow-B-cells-18m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX AGBL3 AKTIP AFAP1 ADAMTS6 CERCAM FAM199X	1.48e-05	180	195	7	7368ab31c3273374ef260f0d710d4eea83cbc4a2
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 MYO9A STOX2 FGFR2 TBL1X AGBL3 CERCAM	1.53e-05	181	195	7	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 DGKB COL12A1 FOLH1 PPFIA2 APOB UNC80	1.71e-05	184	195	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 DGKB COL12A1 FOLH1 PPFIA2 APOB UNC80	1.71e-05	184	195	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HECW1 DGKB COL12A1 FOLH1 PPFIA2 APOB UNC80	1.71e-05	184	195	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGAX PRUNE2 LIPF GSAP NCOA4 AFAP1 TNS1	1.71e-05	184	195	7	8fa30789c9d583188667cf375d2218e392dd40bc
ToppCell	droplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGAX PRUNE2 LIPF GSAP NCOA4 AFAP1 TNS1	1.77e-05	185	195	7	4bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX PRUNE2 LIPF GSAP NCOA4 AFAP1 TNS1	1.89e-05	187	195	7	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAX PRUNE2 LIPF GSAP NCOA4 AFAP1 TNS1	1.89e-05	187	195	7	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COLGALT2 PXDNL SPARCL1 PRUNE2 COL12A1 CCDC88C ADAMTS6	1.96e-05	188	195	7	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	moderate-Lymphoid-NK\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MAP1B PCDH17 SPARCL1 COL12A1 GPR143 ANGPTL4 CDH5	2.03e-05	189	195	7	22a19365782003c18ec8dddcdbfdaa82c4e330f6
ToppCell	droplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITGAX PRUNE2 LIPF GSAP NCOA4 AFAP1 TNS1	2.03e-05	189	195	7	f7e9b6e6a4de297b660a5b6c9a62f860c147185e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAP1B DGKG COLGALT2 NALCN SPARCL1 PPFIA2 TNS1	2.10e-05	190	195	7	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PCSK1 KIF1A CFAP65 NALCN PRUNE2 CDCP1 UNC80	2.10e-05	190	195	7	b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	AK9 SNX13 GGT7 STARD9 METTL18 SRD5A3 ENPP4	2.17e-05	191	195	7	cadb7a9de16f4bb21606de0e25cddd2d748c7f0b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A FGFR2 PRUNE2 MAPK8IP1 FOLH1 INF2 CERCAM	2.64e-05	197	195	7	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DGKB DGKG STARD9 SPARCL1 PRUNE2 ADAMTS6 TNS1	2.73e-05	198	195	7	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	10x3'2.3-week_14-16-Endothelial-stroma-tip_EC\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MAP1B MPDZ PCDH17 STOX2 FOLH1 ANGPTL4 CDH5	2.82e-05	199	195	7	1c69395c9305b6ecb0a826d46c8e8ec95795ad6d
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A FGFR2 PRUNE2 MAPK8IP1 GAL3ST1 FOLH1 CERCAM	2.91e-05	200	195	7	159377d904394d91e09913131e9a93e08189955a
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_only / Treatment groups by lineage, cell group, cell type	MAP1B DOCK11 NBEAL1 DGKG STARD9 PPFIBP2 PPFIA2	2.91e-05	200	195	7	69edc375d85689300d1dbc1217fedc40063ecdcb
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	LVRN PCSK1 HPD ADGRD1 COL12A1 APOB CERCAM	2.91e-05	200	195	7	3e0041c04e42a47257517dae8707a6454570c256
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A FGFR2 PRUNE2 FOLH1 ENPP4 IPO13 CERCAM	2.91e-05	200	195	7	829978708463a7459fe1041bd90196775bc4b531
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	MPDZ PCDH17 PTPRG SPARCL1 COL12A1 RNF213 CDH5	2.91e-05	200	195	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A FGFR2 PRUNE2 MAPK8IP1 GAL3ST1 FOLH1 CERCAM	2.91e-05	200	195	7	0bfd41c12887479ceb62c3db0a3c3ba5007eb62b
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF1A FGFR2 PRUNE2 MAPK8IP1 GAL3ST1 FOLH1 CERCAM	2.91e-05	200	195	7	d30316836494f33ca46d4e415fd2ed179e9cb5ee
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_alveolar-Macro_alv_MT\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	RAB42 TPP1 GAL3ST1 PPFIBP2 NDC1 EXOC1 RASSF4	2.91e-05	200	195	7	f11ae9055e72c938b6c9e52701478b2eee681ac4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 MYO9A PRUNE2 DENND3 AGBL3 PSD4	4.01e-05	143	195	6	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	P07-Hematopoietic-Immune\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGAX KLHL10 HCN3 MREG RASSF4 PSD4	4.16e-05	144	195	6	962698c5c15bd583fccda0593b7aab5f2eb4bc9f
ToppCell	P07-Hematopoietic-Immune-immune_cell_unspecified\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ITGAX KLHL10 HCN3 MREG RASSF4 PSD4	4.16e-05	144	195	6	eb057dbdb2a5a2d29b93e5ed5479a3fd1bf3fd26
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COLGALT2 PCDH17 KLHL10 NCOA4 SELENON CDH5	4.50e-05	146	195	6	2d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCell	Lymphoid-Lymphoid-NK_cells\|Lymphoid / shred on cell class and cell subclass (v4)	ITGAX TRNAU1AP AOAH ENPP4 CD226 TNS1	4.85e-05	148	195	6	d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell	367C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NLGN4X ACAD11 APOB CDCP1 PSD4	6.78e-05	97	195	5	12cbd03b33e76e5e471bbee2a9c11f27e8b21123
ToppCell	367C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	NLGN4X ACAD11 APOB CDCP1 PSD4	6.78e-05	97	195	5	a1279377bf0ee5662db8b9303f5f1fd418dee6df
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	PCSK1 DGKB SPARCL1 PRUNE2 SLC6A11 ADAMTS6	7.48e-05	160	195	6	d783d29150033e9181c0e30870070268fed3fd85
ToppCell	LPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NRROS ITGAX TECPR2 VNN1 LPXN TBL1X	7.48e-05	160	195	6	5d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	MAP1B DGKB ITGA3 SPARCL1 PRUNE2 PPFIA2	7.74e-05	161	195	6	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DGKG SYNGAP1 SPARCL1 GNAS ADGRD1 ADAMTS6	8.01e-05	162	195	6	5d902bb31e691aea9749617cc88303c2448f24b8
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DGKG SYNGAP1 SPARCL1 GNAS ADGRD1 ADAMTS6	8.01e-05	162	195	6	c7114e24cb5525abb9780ca3d35dbcc4eabd4b64
ToppCell	kidney_cells-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DGKG SYNGAP1 SPARCL1 GNAS ADGRD1 ADAMTS6	8.01e-05	162	195	6	f1851a173d3bcca2981d934161ec85d1cc0af5a2
ToppCell	10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8\|GI_large-bowel / Manually curated celltypes from each tissue	KIF1A C6orf52 BAHCC1 TSPAN32 PRDM7 ERN2	9.16e-05	166	195	6	13bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCell	droplet-Heart-nan-18m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NALCN VNN1 FOLH1 PPFIA2 GAA ARHGAP33	9.16e-05	166	195	6	9adceb746e67e955fd8b3e0984f4eed44b64a270
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAD11 HPD SELENBP1 SHMT1 MREG SLC16A5	9.16e-05	166	195	6	4b63ecedf21285974f0d188979fcdced27bf9ef9
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACAD11 HPD SELENBP1 SHMT1 MREG SLC16A5	9.16e-05	166	195	6	d6d29b0dc1ef471b1227495f349963ab37f22ec4
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	TECPR2 TRNAU1AP SELENBP1 MFSD9 CDCP1 DEPDC5	9.79e-05	168	195	6	8697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|World / disease group, cell group and cell class (v2)	CNTROB SELENBP1 PPFIBP2 MREG ZNF85 TDP1	1.01e-04	169	195	6	2bda6ab3f32e05cb7daf91eb7c39b4fcc9ae91bb
ToppCell	COVID-19-Heart-Adipocyte\|Heart / Disease (COVID-19 only), tissue and cell type	LVRN TBL1Y KLB PRUNE2 SHMT1 MREG	1.01e-04	169	195	6	bd39f85b48207955f80ca120a11e15a0124117b9
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-4\|TCGA-Liver / Sample_Type by Project: Shred V9	GNAS CDCA4 GAL3ST1 CCDC88C SLC6A11 MAPK13	1.01e-04	169	195	6	0a3ba6b5d6cff9d3d7f56046063cfc3a37ae1156
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue\|TCGA-Endometrium / Sample_Type by Project: Shred V9	DGKB STARD9 SPARCL1 ADGRD1 PRUNE2 TNS1	1.04e-04	170	195	6	516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DGKG SPARCL1 GNAS ADGRD1 DENND3 ADAMTS6	1.04e-04	170	195	6	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DGKG SPARCL1 GNAS ADGRD1 DENND3 ADAMTS6	1.04e-04	170	195	6	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium\|TCGA-Endometrium / Sample_Type by Project: Shred V9	DGKB STARD9 SPARCL1 ADGRD1 PRUNE2 TNS1	1.04e-04	170	195	6	cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCell	TCGA-Endometrium-Solid_Tissue_Normal\|TCGA-Endometrium / Sample_Type by Project: Shred V9	DGKB STARD9 SPARCL1 ADGRD1 PRUNE2 TNS1	1.04e-04	170	195	6	0bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DGKG SPARCL1 GNAS ADGRD1 DENND3 ADAMTS6	1.04e-04	170	195	6	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	CNTROB SELENBP1 PPFIBP2 MREG AKTIP ZNF85	1.08e-04	171	195	6	78491478ba65bad45238fe114f5251b2adea323d
ToppCell	E12.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KIF1A CUL9 NRROS STARD9 INF2 VPS13B	1.11e-04	172	195	6	3b9be685fcd1634498a603b692f5ac6ddd0de176
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MAP1B PXDNL SPARCL1 PRUNE2 PPFIA2 TNS1	1.15e-04	173	195	6	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSMD2 PCDH17 NLGN4X PTPRG NALCN KIF23	1.22e-04	175	195	6	cc596907ea1a64ab7b5a8c7d4ad12e6ee59bfed9
ToppCell	Pericytes-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	MAP1B DGKG HPD SPARCL1 PRUNE2 PPFIA2	1.22e-04	175	195	6	ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK11 ZNF462 STOX2 FGFR2 TBL1X AGBL3	1.22e-04	175	195	6	284fdc7a9d303636a637041846850d19d114861a
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSMD2 PCDH17 NLGN4X PTPRG NALCN KIF23	1.22e-04	175	195	6	8a3abf40146ae3459d97cdf865c1c8f6b92ac639
ToppCell	10x_5'_v1-Neoplastic-Stem-like\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSMD2 PCDH17 NLGN4X PTPRG NALCN KIF23	1.22e-04	175	195	6	a8400e7e47379901dcab5f2e364c3ff17765b4b9
ToppCell	10x_5'_v1-Neoplastic-Stem-like-OPC-like-OPC-like-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CSMD2 PCDH17 NLGN4X PTPRG NALCN KIF23	1.22e-04	175	195	6	378d2b79edac91fc74eee0fb42bb29dd9b07c36f
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HECW1 KIF1A MAP1B DGKB NALCN UNC80	1.26e-04	176	195	6	116741fef5895ca85057d2d31eca9eba5764ab44
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HECW1 KIF1A MAP1B DGKB NALCN UNC80	1.26e-04	176	195	6	5b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	LYST KCNJ5-AS1 SUN1 NUP98 RNF213 ENPP4	1.26e-04	176	195	6	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK1 SUPT7L LPXN KIF23 TSPAN32 PSD4	1.30e-04	177	195	6	1730e640986e50943bd781b7d949bcc5b7c12dde
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	LYST KCNJ5-AS1 SUN1 NUP98 RNF213 ENPP4	1.30e-04	177	195	6	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	facs-Lung-18m-Hematologic-Lymphocytic_NK_ILC-Alox5+_lymphocyte-Alox5+_lymphocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK1 SUPT7L LPXN KIF23 TSPAN32 PSD4	1.30e-04	177	195	6	b7cfa3776f58377e35830780650d236b5cceecee
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	LVRN DOCK11 KLB MREG ANGPTL4 RASSF4	1.30e-04	177	195	6	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NBEAL1 LYST CASP8AP2 TMEM87A CCDC88C CDH5	1.34e-04	178	195	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	RV-11._Adipocyte\|RV / Chamber and Cluster_Paper	LVRN DOCK11 KLB MREG ANGPTL4 RASSF4	1.34e-04	178	195	6	278bbea5cf8f0589f71675c7a3d00679391b5253
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF1A MAP1B KLB PRUNE2 MAPK8IP1 MREG	1.34e-04	178	195	6	30ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	STK11IP KCNJ5-AS1 PRUNE2 MASTL ZNF85 ARHGAP33	1.38e-04	179	195	6	ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	CUL9 STARD9 KCNJ5-AS1 ARHGAP35 ZNF253 IPO13	1.38e-04	179	195	6	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 PLB1 HECW1 DGKB DGKG PPFIBP2	1.43e-04	180	195	6	0059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCSK1 PLB1 HECW1 DGKB DGKG PPFIBP2	1.43e-04	180	195	6	dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
Drug	Isoxicam [34552-84-6]; Down 200; 12uM; PC3; HT_HG-U133A	MPDZ LYST ME3 KLK5 ABCF2 ARHGAP35 ERN2 DENND3 AFAP1 INF2 TNS1	1.18e-06	200	193	11	7268_DN
Disease	obsolete_red blood cell distribution width	LVRN TPP2 ATR AK9 ITGAX SNX13 ME3 PIM1 SELENBP1 HCN3 SUN1 AOAH SHMT1 APOB TSPAN32 NCOA4 APLF ANGPTL4 HELZ2 FUT3 PPP6R3	1.01e-04	1347	183	21	EFO_0005192
Disease	Hydrocephalus	MPDZ CCDC88C	1.14e-04	3	183	2	cv:C0020255
Disease	Congenital hydrocephalus	MPDZ CCDC88C	1.14e-04	3	183	2	cv:C0020256
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1X	1.14e-04	3	183	2	DOID:0050155 (implicated_via_orthology)
Disease	Benign neoplasm of stomach	ATR PIK3CA FGFR2	1.50e-04	17	183	3	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ATR PIK3CA FGFR2	1.50e-04	17	183	3	C0496905
Disease	Carcinoma in situ of stomach	ATR PIK3CA FGFR2	1.50e-04	17	183	3	C0154060
Disease	Stomach Carcinoma	ATR PIK3CA FGFR2	2.87e-04	21	183	3	C0699791
Disease	Dyslipidemias	VNN1 APOB ANGPTL4	4.31e-04	24	183	3	C0242339
Disease	Dyslipoproteinemias	VNN1 APOB ANGPTL4	4.31e-04	24	183	3	C0598784
Disease	hydrocephalus (is_implicated_in)	MPDZ CCDC88C	5.65e-04	6	183	2	DOID:10908 (is_implicated_in)
Disease	body surface area	PCSK1 KIF1A DGKG COLGALT2 ZNF462 PTPRG GNAS PRDM4 GUSB ALKBH3 PPP6R3 PSD4	7.20e-04	643	183	12	EFO_0022196
Disease	Autism spectrum disorder	NLGN4X TBR1	7.87e-04	7	183	2	cv:C1510586
Disease	reticulocyte measurement	ATR USP9X PPCDC ITGAX SNX13 GGT7 PIK3CA KLHL10 CTDSP1 DENND3 CD226 ANGPTL4 DEPDC5 TRIM40 TNS1 GAA	9.13e-04	1053	183	16	EFO_0010700
Disease	X-24747 measurement	ACAD11 ACOT6	1.05e-03	8	183	2	EFO_0022135
Disease	neuroimaging measurement	MAP1B NBEAL1 BCL2L1 ZNF462 ENO4 ACAD11 FGFR2 BAHCC1 ANKS1A GAL3ST1 ARHGAP35 DENND3 CCDC88C AFAP1 SSH2 TNS1	1.07e-03	1069	183	16	EFO_0004346
Disease	Head and Neck Neoplasms	BCL2L1 PIK3CA FGFR2	1.12e-03	33	183	3	C0018671
Disease	Schizophrenia	SPTBN2 CSMD2 PCDH17 CFAP65 SYNGAP1 PIK3CA FGFR2 GNAS SELENBP1 FOLH1 SHMT1 ACOT6 SLC6A11 ERVK-8	1.28e-03	883	183	14	C0036341
Disease	Hamartoma Syndrome, Multiple	PIK3CA FGFR2	1.34e-03	9	183	2	C0018553
Disease	Colorectal Carcinoma	MAP1B SPTBN2 NLGN4X PIK3CA GNAS DONSON SELENBP1 FOLH1 APOB ATAD1 CD226 CDH5	1.52e-03	702	183	12	C0009402
Disease	Head and Neck Carcinoma	PIK3CA FGFR2	1.67e-03	10	183	2	C3887461
Disease	Intellectual Disability	MAP1B NUP62 SYNGAP1 ZNF462 TPP1 FGFR2 GNAS TCTN1 SRD5A3	1.99e-03	447	183	9	C3714756
Disease	Gastric cancer	PIK3CA FGFR2	2.03e-03	11	183	2	cv:C0024623
Disease	Neoplasm of stomach	PIK3CA FGFR2	2.03e-03	11	183	2	cv:C0038356
Disease	chemotherapy-induced alopecia, response to antimicrotubule agent	ME3 ZNF462	2.03e-03	11	183	2	EFO_0005260, EFO_0005400
Disease	GASTRIC CANCER	PIK3CA FGFR2	2.03e-03	11	183	2	613659
Disease	brain measurement, neuroimaging measurement	ZNF462 ACAD11 BAHCC1 ANKS1A GAL3ST1 DENND3 CCDC88C AFAP1 SSH2 TNS1	2.39e-03	550	183	10	EFO_0004346, EFO_0004464
Disease	visual epilepsy (biomarker_via_orthology)	PCSK1 MAP1B PRICKLE1 SLC6A11	2.42e-03	90	183	4	DOID:11832 (biomarker_via_orthology)
Disease	Malignant Head and Neck Neoplasm	BCL2L1 PIK3CA FGFR2	2.58e-03	44	183	3	C0278996
Disease	Stomach Neoplasms	ATR BCL2L1 PTPRG PIK3CA FGFR2 SELENBP1 ARFGAP2	2.63e-03	297	183	7	C0038356
Disease	Malignant neoplasm of stomach	ATR BCL2L1 PTPRG PIK3CA FGFR2 SELENBP1 ARFGAP2	2.78e-03	300	183	7	C0024623
Disease	drug use measurement, depressive symptom measurement, SSRI use measurement	CSMD2 AKTIP	2.85e-03	13	183	2	EFO_0007006, EFO_0007010, EFO_0007011
Disease	FVC change measurement, response to placebo	KIF1A DGKB	2.85e-03	13	183	2	EFO_0008344, EFO_0010339
Disease	heart rate variability measurement, response to antipsychotic drug	COLGALT2 COL12A1 PRSS56	2.93e-03	46	183	3	EFO_0008003, GO_0097332
Disease	red blood cell density measurement	ATR MYO9A BCL2L1 ME3 ZNF462 PIK3CA CTDSP1 TSPAN32 NCOA4 SSH2 VPS13B TTC33 PSD4	3.48e-03	880	183	13	EFO_0007978
Disease	IGF-1 measurement	SPTBN2 DGKB ZNF462 STARD9 GNAS KLB SUN1 NUP98 PIWIL4	3.56e-03	488	183	9	EFO_0004627
Disease	triglyceride measurement, alcohol consumption measurement	PLB1 SNX13 APOB ANGPTL4	3.66e-03	101	183	4	EFO_0004530, EFO_0007878
Disease	low density lipoprotein cholesterol measurement, response to selective serotonin reuptake inhibitor	CSMD2 ADAMTS6	3.81e-03	15	183	2	EFO_0004611, EFO_0005658
Disease	Hypertriglyceridemia	APOB ANGPTL4	3.81e-03	15	183	2	C0020557
Disease	amenorrhea, response to antineoplastic agent	PPCDC APOB	3.81e-03	15	183	2	EFO_0010269, GO_0097327
Disease	X-17654 measurement	ACOT6 MREG	3.81e-03	15	183	2	EFO_0800784
Disease	mean corpuscular hemoglobin concentration	ATR PPCDC SNX13 ME3 PIK3CA HPD PIM1 MAPK8IP1 CTDSP1 TSPAN32 NCOA4 CD226 VPS13B GAA PPP6R3	3.85e-03	1105	183	15	EFO_0004528
Disease	cortical thickness	NBEAL1 SPTBN2 CUL9 BCL2L1 PCDH17 ZNF462 ENO4 ANKS1A COL12A1 ARHGAP35 ARPC5 DENND3 SPATA16 SSH2 TNS1	4.11e-03	1113	183	15	EFO_0004840
Disease	Congenital Myasthenic Syndromes, Postsynaptic	AK9 CHRNG	4.89e-03	17	183	2	C0751883
Disease	triglyceride measurement, intermediate density lipoprotein measurement	APOB TYW1B ANGPTL4 TNKS2	5.12e-03	111	183	4	EFO_0004530, EFO_0008595
Disease	urate measurement, bone density	PLB1 PCDH17 PTPRG CASP8AP2 PPFIA2 AOAH SEC31A SELENON HELZ2 ALKBH3	5.48e-03	619	183	10	EFO_0003923, EFO_0004531
Disease	Malignant neoplasm of endometrium	ATR FGFR2	5.48e-03	18	183	2	C0007103
Disease	esophageal adenocarcinoma	HECW1 SPARCL1	5.48e-03	18	183	2	EFO_0000478
Disease	Carcinoma in situ of endometrium	ATR FGFR2	5.48e-03	18	183	2	C0346191
Disease	triglycerides in IDL measurement	APOB ANGPTL4 TNKS2	5.64e-03	58	183	3	EFO_0022149
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A CHRNG	6.10e-03	19	183	2	C0751884
Disease	unipolar depression, response to bupropion, mood disorder	STOX2 ADAMTS6	6.10e-03	19	183	2	EFO_0003761, EFO_0004247, EFO_0006326

Protein segments in the cluster

Peptide	Gene	Start	Entry
WNHDMTDFLENPLGT	PTPRG	326	P23470
MQALRPSAQHSWSPE	GNAS	66	P84996
AWQNPHMLFLDEPTN	ABCF2	531	Q9UG63
APHALADVMDQASLW	BAHCC1	886	Q9P281
DVMANSSEWVQSKPH	AGBL3	891	Q8NEM8
ASWDEMNVLAHGLLQ	ANGPTL4	36	Q9BY76
LPTWMLAEHLSDQNL	APLF	186	Q8IW19
TSVPDLIVSTNHQMW	CSMD2	481	Q7Z408
NNIWPAHTKIAEAMH	ADGRD1	436	Q6QNK2
EDELMTWQFVVPAHL	CDCP1	246	Q9H5V8
TENGEWAIQHRPAKM	CHRNG	201	P07510
KTRHQWPSEEASMDL	AFAP1	136	Q8N556
SDVDWENLQHQTMPF	MASTL	836	Q96GX5
WNPSVHDEAREKMLT	AKTIP	241	Q9H8T0
IMEGATQADWQHRVP	ALKBH3	246	Q96Q83
IAAWMATYLNDHLEP	BCL2L1	166	Q07817
TFMDTWSNPLEEHNH	ACOT6	291	Q3I5F7
VWDLNMESRPVETHQ	PPP2R2D	316	Q66LE6
HLQGAIEDWNNESSM	ADPRM	51	Q3LIE5
TDLWIDNMSSAVPNH	ARFGAP2	131	Q8N6H7
DMDQDAQSHASVSWV	ANKS1A	1106	Q92625
AVLTQHSMPVFWNQS	DNHD1	4221	Q96M86
IALPSFDNHAMENWG	LVRN	371	Q6Q4G3
AEAQEVSLPWLVMEH	DENND3	701	A2RUS2
VDAMHQWENTPLKAE	CASP8AP2	451	Q9UKL3
WNQMHIDEEKNTSLP	CDH5	51	P33151
MAAHITANTNPFSWS	ADAMTS6	431	Q9UKP5
AHQDIPAMQQLSEWL	ACAD11	191	Q709F0
SPSDNSSAMLLQWHE	ARPC5	116	O15511
DRQFHSIPATWQALM	NBEAL1	2131	Q6ZS30
NGEQHHWDMSLPLIV	PCDH17	696	O14917
IQDWHQEVMATQGPD	RAB42	106	Q8N4Z0
MQDDREQVHLPSTSW	RASSF4	71	Q9H2L5
AVWMDVEVSHPQNPS	ITGAX	981	P20702
MENLTISAAHWLTAP	NOX5	201	Q96PH1
AHFHISPEWITASQM	AOAH	266	P28039
PDRVAMQQPATTWHT	DEPDC5	1266	O75140
MQQPATTWHTAGVDD	DEPDC5	1271	O75140
NQHWSLIMESVVPSD	FGFR2	211	P21802
TMQLVDWHQLQADSF	NUP98	1376	P52948
QWGSNMQVTLIPTHD	MAP1B	2411	P46821
EDAGLHLSSPWMQQR	LYSMD1	186	Q96S90
LPWQEPAMNTHSSRQ	MGAM2	1671	Q2M2H8
HWDMNSAPRLVSETA	MFSD9	6	Q8NBP5
PEHMAALAKNSDWVD	MAPK8IP1	551	Q9UQF2
QISPMSAFVENHLEW	HECW1	1326	Q76N89
WAEQAELNSTELHQM	CFAP65	1216	Q6ZU64
DNWHEHISMPLQTDL	ERN2	821	Q76MJ5
HAAISWELDNVLMPS	KCNJ5-AS1	21	Q8TAV5
QWLNSEEAMNLHPVE	FICD	336	Q9BVA6
MWNLLHETDSAVATA	FOLH1	1	Q04609
LQGSLHMWIDIFPQD	FER1L4	1461	A9Z1Z3
ALVPWAVHMFSAQEA	G6PC3	326	Q9BUM1
MNESAHLGWELEQLS	CCDC88C	426	Q9P219
NKHRNLDELPWSAMT	FAM199X	171	Q6PEV8
NHLDFIWAMDAPQEV	LIPF	371	P07098
ALEANPFLTWRDMQH	PCSK4	386	Q6UW60
QMLDFSWPNRTANHS	GGT7	511	Q9UJ14
LQLSTSSHQDNLWPM	ITGA3	736	P26006
LWENLNVIITSDHGM	ENPP4	226	Q9Y6X5
PVASWFDNMSDTELH	CTDSP1	221	Q9GZU7
DAMTRHLAVEWGPQN	DECR2	186	Q9NUI1
PNALWQMDVTHVPSF	HERVK_113	646	P63132
PEVILSWMHYNQTVD	MAPK13	191	O15264
PVLENYLSAMDTVWH	LPXN	276	O60711
WEHKSMENAAPSQDT	METTL18	61	O95568
SDCDMHTQPWQAALL	KLK5	71	Q9Y337
HLAQEEADWSPDMLA	MIEF1	391	Q9NQG6
HMDSLQWIDQNSALL	NUP62	481	P37198
QDFPPDCWVSINHMV	HCN3	276	Q9P1Z3
PNALWQMDVTHVPSF	ERVK-7	646	P63135
PNALWQMDVTHVPSF	ERVK-6	646	Q9BXR3
KLPSNVAREHNSMWA	INF2	571	Q27J81
ITHPMVNDADASLWQ	NHLRC2	141	Q8NBF2
FPDMSVIEEHANWSV	PIK3CA	486	P42336
SPSEVVQWSNHRVME	PPFIBP2	711	Q8ND30
TPSMVTEDWLVQNHQ	NCOA4	381	Q13772
MAPWAEAEHSALNPL	SRD5A3	1	Q9H8P0
QPNEMDIRASEHWIS	PRICKLE1	431	Q96MT3
MATELSALNPHWEGN	PXDNL	981	A1KZ92
NTSMHARNLAIVWAP	ARHGAP33	456	O14559
QMLHIAQYLEWDPTE	DGKG	206	P49619
AVDAAAIQDEAMQPW	GAL3ST1	351	Q99999
ALSAIAQWMAIPDHA	ECI1	236	P42126
LWDHPMSSNIISRNH	GSAP	766	A4D1B5
LSPWQMSALVQVHAS	APOB	3591	P04114
WPVVMSRFLSQLDEH	ATR	171	Q13535
NQWTLIAPMHEQRSD	KLHL10	411	Q6JEL2
LMNCHWQPLDTVHSE	C6orf52	131	Q5T4I8
IHEQILQEDTMHSPW	DOCK11	2031	Q5JSL3
LQEDTMHSPWMSNTL	DOCK11	2036	Q5JSL3
IDENTVHMSWAKPVD	COL12A1	36	Q99715
ANTWTALPPMNEARH	GAN	351	Q9H2C0
PAVVMWSVANEPASH	GUSB	441	P08236
SVSDMNHTEIWPAAF	GPR143	101	P51810
MTNQEKWAHLSPSEF	DGKB	1	Q9Y6T7
ALMIQVWADPHNATL	LYST	1546	Q99698
MTRAHFPLDVQWNDL	GAA	391	P10253
GHLATMLNSWPEDNI	ME3	166	Q16798
SPWSNDATLQHVLMS	DONSON	246	Q9NYP3
QWVNSTITHELQGMA	ENO4	136	A6NNW6
GSHWIEPNRSENTMD	KLB	301	Q86Z14
LPHDIRWELNAMTTN	KLHDC3	356	Q9BQ90
EHILMWLSAPEVYAN	CUL9	61	Q8IWT3
MSHHVWTAQNVDPAS	EXOC1	616	Q9NV70
VLWHTSVPFAENMSL	CD226	21	Q15762
PKSRMAIWAATDHNV	COLGALT2	81	Q8IYK4
QMVAFDQALPWEHRS	HELZ2	66	Q9BYK8
MTFRLWHQAVDTLPE	HELZ2	476	Q9BYK8
HNVDNTTEMLQEWLA	CERCAM	71	Q5T4B2
NFPVVEASWSMLHDE	RXYLT1	251	Q9Y2B1
LSEWLADHPVMINSV	IPO13	516	O94829
HDMLPIWFTANLDTL	NLGN4X	121	Q8N0W4
MLQAHWDEANQLLST	CNTROB	556	Q8N137
EAAWDSSMHNSLLLN	KIF1A	1241	Q12756
ALQHGQTVADWAMVT	NRROS	606	Q86YC3
PSGNVWVTHEEMENL	PPFIA2	976	O75334
WVTHEEMENLAAPAK	PPFIA2	981	O75334
PLIGQQSHSMEVAEW	PRDM4	441	Q9UKN5
AWILQVPSEHLAMNF	PRSS56	491	P0CW18
LNVPMSSQLAANHWN	UPF2	1186	Q9HAU5
GDRWVDHKPASNMQT	KIF23	816	Q02241
DADLWSSHDKMLAQP	SHMT1	11	P34896
IASIDHLNAPLMWDH	ORC2	421	Q13416
SDRPTFEEIQNHPWM	PIM1	276	P11309
PQADTVIVHHWDIMS	FUT3	101	P21217
LSSALNPWNKEMGDH	HPD	71	P32754
NNHPETELALMLNWH	AK9	1451	Q5TCS8
AGWFVQQHPELELMS	STK11IP	406	Q8N1F8
HVDWMTSPEQVADSV	SNX13	831	Q9Y5W8
LWNLAHSDDVPVDIM	USP9X	511	Q93008
QQWLGQLEHMPAEAA	TRIM40	176	Q6P9F5
DALMDCHWQPLDTVS	TRNAU1AP	266	Q9NX07
DSPNTGAHWMRQEIS	TBR1	291	Q16650
DMWASPHTDNSSEIN	PRUNE2	1031	Q8WUY3
AVTHDNEWEMLSPQP	PRUNE2	2716	Q8WUY3
MSWNISHPQLSDKLF	TDRD10	1	Q5VZ19
NLWSMPHDVSHTEAD	MREG	51	Q8N565
HLSAKQMPSHWDSEQ	PHF12	446	Q96QT6
QMPSHWDSEQTEKAD	PHF12	451	Q96QT6
MWNAITPLRTSQDHL	PRDM7	436	Q9NQW5
AEHENLRTPMNSSWL	PSD4	541	Q8NDX1
MQDHICQPVSAADWS	PIWIL4	456	Q7Z3Z4
HNVMISTEWAAPNVL	SELENBP1	196	Q13228
RSLMPSEINHLEWNV	SPATA31D4	611	Q6ZUB0
DLQALHMLPQTVDWS	SPATA16	361	Q9BXB7
LHSNSWDPQQMALLN	MT-ND5	191	P03915
PVTGMWDHLQEQAND	PNKP	261	Q96T60
VNASPLWNLAHVKME	SUPT7L	331	O94864
WHLEDSSLPVMDQEA	STARD9	1236	Q9P2P6
ENMGHTNLPDSRDVW	STARD9	4426	Q9P2P6
HSRAASALWNNMLEP	PLB1	661	Q6P1J6
TPWDATSHIDNMENE	ARHGAP35	386	Q9NRY4
IAAHLVDPLNMHVTW	ATAD1	76	Q8NBU5
QAPRHLQSSAWEMDG	CDCA4	136	Q9BXL8
TAMWEHPITAQQVDQ	PPCDC	141	Q96CD2
AALWFPEHQRATANM	SLC49A3	151	Q6UXD7
HTNEVNAIKWDPSGM	TBL1X	411	O60907
PQVLHSLMEARWNHE	RNF213	3836	Q63HN8
WASQHSLLSQEAMGP	TLX1NB	16	P0CAT3
DHASSMPNAESWPVV	TDP1	381	Q9NUW8
RSLMPSEINHLEWNV	SPATA31D3	611	P0C874
IQPAAWELLLSMDEH	UNC80	1591	Q8N2C7
SQTIWVNCHVSMEPE	UBTFL1	351	P0CB47
TAWMNVLPHLSAVEF	VNN1	236	O95497
EVQAPLAMWEAGIQH	MPDZ	686	O75970
PYAMWHSVDEQQAAL	SLC16A5	261	O15375
SQDILMASRWHPAQQ	SPATA46	166	Q5T0L3
HMQAVAEAWAQLQGS	SPTBN2	1881	O15020
PVSVQAMWSALQSLH	SSH2	171	Q76I76
AWVSNMPHLSADIES	SYNGAP1	1156	Q96PV0
INSHLLTAQPWMDDL	RINT1	131	Q6NUQ1
WRLHSPTQVEDAMLD	TSPAN32	111	Q96QS1
NTNVLESHFPMTPEW	STOX2	426	Q9P2F5
PVHWQFSELDQHPMD	SPARCL1	591	Q14515
LFVPNHRSLNVDMEW	SELENON	331	Q9NZV5
AMDTWLNADPHNVVV	TNS1	96	Q9HBL0
PNALWQMDVTHVPSF	ERVK-10	646	P10266
NSQAQDMLDWVPIHF	TCTN1	476	Q2MV58
PNALWQMDVTHVPSF	ERVK-8	646	P63133
NSSWVQCPSHLELMN	TPP2	576	P29144
PNALWQMDVTHVPSF	ERVK-11	646	Q9UQG0
LQNATSPVMEFWEHR	SLC6A11	196	P48066
SVHSSPNDQMLWVLD	TECPR2	1271	O15040
FHSAPALDVDWQNNM	TBL1Y	316	Q9BQ87
DFPQMVSTSHPNAEW	RIOK2	246	Q9BVS4
NAMDLWQFTPLHEAA	TNKS2	271	Q9H2K2
QHWESLMNGPVQDSE	ZNFX1	756	Q9P2E3
WIMQNETGISHDAIA	ZC3H7A	661	Q8IWR0
VMSSHFAQDLWPENI	ZNF253	76	O75346
PALEWNMASSIRRHQ	VPS13B	1666	Q7Z7G8
FHPWAMNGDESVLLD	ZNF462	1391	Q96JM2
TVMCSHFAQDLWPEQ	ZNF85	76	Q03923
AVDSLIWQPNSLNMH	UBXN10	21	Q96LJ8
LNWASMHRTQRVDDP	SUN1	321	O94901
PSLNLSCADVVWHQM	WDR24	71	Q96S15
VWHQMDENLLATAAT	WDR24	81	Q96S15
ILQAHDSPVRAMTWS	WDR33	156	Q9C0J8
VDRTAMQAWSPAQNH	SEC31A	6	O94979
WHPDVATQMVLASED	SEC31A	221	O94979
PNWSANFDVPMETTH	PPP6R3	681	Q5H9R7
SLTMAHVPWHEEVVQ	TYW1B	551	Q6NUM6
PEMVPVSHNNLQSAW	VWA3A	561	A6NCI4
DKTAMHEPLQTWQDA	TMEM87A	166	Q8NBN3
SQIMSLSHSPQEDWV	TLE6	461	Q9H808
AEMAVQQNPHSWESW	TTC33	116	Q6PID6
QWLMLLSNESALPHV	TPP1	306	O14773
DQTLNAVGHMWAPVV	NALCN	561	Q8IZF0
DSMHWQNDSVQIIAS	MYO9A	1846	B2RTY4
IQAVFSDAQMHIWAL	NDC1	551	Q9BTX1
DMQHLVVWTSEYDPL	PCSK1	406	P29120