Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	AKAP6 ANKRD13D ZXDC TCOF1 SYNE1 NACA CGAS BRD3 SSX8P HMGA1 DPF2 SSX5 KAT2B ARID1B SMARCC2 DOT1L HDGFL2 NIPBL MED13 HDAC1	9.34e-05	1160	134	20	GO:0030674
GeneOntologyMolecularFunction	transcription coregulator activity	ZXDC NACA SSX8P HMGA1 DPF2 SSX5 KAT2B ARID1B SMARCC2 DOT1L NIPBL MED13 HDAC1	1.07e-04	562	134	13	GO:0003712
GeneOntologyMolecularFunction	chromatin binding	CGAS CENPS BRD3 HMGA1 ATAD2 MEOX1 KAT2B ARID1B SAFB MCM9 KMT2A SMARCC2 POLQ NIPBL HDAC1	1.33e-04	739	134	15	GO:0003682
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC2H1 DNAH2 DNAH7	2.24e-04	18	134	3	GO:0008569
GeneOntologyMolecularFunction	H3K9me3 modified histone binding	DPF2 HDGFL2	2.66e-04	4	134	2	GO:0062072
GeneOntologyMolecularFunction	molecular adaptor activity	AKAP6 ANKRD13D ZXDC TCOF1 SYNE1 NACA CGAS BRD3 SSX8P HMGA1 DZIP1 DPF2 SSX5 KAT2B ARID1B SMARCC2 DOT1L HDGFL2 NIPBL MED13 HDAC1	2.72e-04	1356	134	21	GO:0060090
GeneOntologyMolecularFunction	modification-dependent protein binding	ANKRD13D CGAS BRD3 DPF2 PHF20L1 KMT2A HDGFL2	4.88e-04	206	134	7	GO:0140030
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DYNC2H1 DNAH2 DNAH7	8.56e-04	28	134	3	GO:0051959
GeneOntologyMolecularFunction	transcription coactivator activity	ZXDC NACA HMGA1 KAT2B ARID1B SMARCC2 DOT1L MED13	1.02e-03	303	134	8	GO:0003713
GeneOntologyMolecularFunction	lysine-acetylated histone binding	BRD3 DPF2 KMT2A	1.05e-03	30	134	3	GO:0070577
GeneOntologyMolecularFunction	acetylation-dependent protein binding	BRD3 DPF2 KMT2A	1.16e-03	31	134	3	GO:0140033
GeneOntologyMolecularFunction	5'-deoxyribose-5-phosphate lyase activity	HMGA1 POLQ	1.22e-03	8	134	2	GO:0051575
GeneOntologyMolecularFunction	microtubule motor activity	DYNC2H1 KIF26B DNAH2 DNAH7	1.26e-03	70	134	4	GO:0003777
GeneOntologyBiologicalProcess	epigenetic regulation of gene expression	RBM15 ARID4B ARID4A ZDBF2 ATAD2 TDRD1 RIF1 KAT2B ARID1B KMT2A DOT1L HDAC1 TDRD12	1.73e-07	330	130	13	GO:0040029
GeneOntologyBiologicalProcess	chromatin remodeling	RBM15 ARID4B ARID4A BRD3 ZDBF2 HMGA1 DPF2 ATAD2 TDRD1 RIF1 KAT2B ARID1B KMT2A SMARCC2 DOT1L HDGFL2 NIPBL HDAC1 TDRD12	2.03e-07	741	130	19	GO:0006338
GeneOntologyBiologicalProcess	chromatin organization	RBM15 ARID4B ARID4A BRD3 ZDBF2 HMGA1 DPF2 ATAD2 TDRD1 RIF1 KAT2B ARID1B SAFB KMT2A SMARCC2 DOT1L HDGFL2 NIPBL HDAC1 TDRD12	8.42e-07	896	130	20	GO:0006325
GeneOntologyBiologicalProcess	protein-DNA complex organization	RBM15 ARID4B ARID4A BRD3 ZDBF2 HMGA1 DPF2 ATAD2 TDRD1 RIF1 KAT2B ARID1B SAFB KMT2A SMARCC2 DOT1L HDGFL2 NIPBL HDAC1 TDRD12	4.42e-06	999	130	20	GO:0071824
GeneOntologyBiologicalProcess	DNA repair	CGAS USP43 CENPS HMGA1 DPF2 RIF1 KAT2B ARID1B MCM9 SMARCC2 PRPF19 DOT1L POLQ HDGFL2 NIPBL	1.46e-05	648	130	15	GO:0006281
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	RBM15 ARID4B ARID4A NACA AKNA ZNF300 BRD3 HMGA1 MLXIP PTBP1 MEOX1 HOXA10 KAT2B OTX1 SAFB MKX KMT2A TNKS DOT1L MGA NIPBL MED13 HDAC1	1.81e-05	1390	130	23	GO:0045944
GeneOntologyBiologicalProcess	regulation of double-strand break repair	CGAS DPF2 RIF1 ARID1B SMARCC2 POLQ HDGFL2	3.94e-05	146	130	7	GO:2000779
GeneOntologyBiologicalProcess	double-strand break repair	CGAS DPF2 RIF1 ARID1B MCM9 SMARCC2 PRPF19 POLQ HDGFL2 NIPBL	4.02e-05	324	130	10	GO:0006302
GeneOntologyBiologicalProcess	DNA metabolic process	JADE3 CGAS USP43 TWNK CENPS HMGA1 DPF2 RIF1 KAT2B ARID1B MCM9 SMARCC2 PRPF19 TNKS ZNF830 DOT1L POLQ HDGFL2 NIPBL	4.76e-05	1081	130	19	GO:0006259
GeneOntologyBiologicalProcess	heterochromatin formation	RBM15 TDRD1 RIF1 KMT2A DOT1L HDAC1 TDRD12	7.92e-05	163	130	7	GO:0031507
GeneOntologyBiologicalProcess	regulation of DNA repair	CGAS DPF2 RIF1 KAT2B ARID1B SMARCC2 POLQ HDGFL2	1.21e-04	234	130	8	GO:0006282
GeneOntologyBiologicalProcess	regulation of stem cell population maintenance	ARID4B ARID4A DPF2 WDR43 HDAC1	1.34e-04	78	130	5	GO:2000036
GeneOntologyBiologicalProcess	positive regulation of delayed rectifier potassium channel activity	AKAP6 AKAP7	2.35e-04	4	130	2	GO:1902261
GeneOntologyBiologicalProcess	protein localization to endoplasmic reticulum	NACA SRP68 SRPRB MACF1 SEC63	2.64e-04	90	130	5	GO:0070972
GeneOntologyBiologicalProcess	positive regulation of stem cell population maintenance	ARID4B ARID4A DPF2 HDAC1	2.99e-04	51	130	4	GO:1902459
GeneOntologyBiologicalProcess	negative regulation of gene expression, epigenetic	RBM15 TDRD1 RIF1 KMT2A DOT1L HDAC1 TDRD12	3.07e-04	203	130	7	GO:0045814
GeneOntologyBiologicalProcess	protein targeting to ER	SRP68 SRPRB MACF1 SEC63	3.23e-04	52	130	4	GO:0045047
GeneOntologyBiologicalProcess	positive regulation of double-strand break repair	DPF2 RIF1 ARID1B SMARCC2 HDGFL2	3.39e-04	95	130	5	GO:2000781
GeneOntologyBiologicalProcess	nucleosome disassembly	HMGA1 ATAD2 SMARCC2	3.45e-04	22	130	3	GO:0006337
GeneOntologyBiologicalProcess	DNA damage response	CGAS USP43 CENPS HMGA1 DPF2 RIF1 KAT2B ARID1B MCM9 SMARCC2 PRPF19 ZNF830 DOT1L POLQ HDGFL2 NIPBL	3.55e-04	959	130	16	GO:0006974
GeneOntologyBiologicalProcess	protein targeting to membrane	NACA SRP68 SRPRB ZDHHC23 MACF1 SEC63	3.67e-04	149	130	6	GO:0006612
GeneOntologyBiologicalProcess	chromosome organization	TWNK HMGA1 DPF2 RIF1 KAT2B ARID1B MCM9 SMARCC2 TNKS ZNF830 DOT1L POLQ NIPBL	4.01e-04	686	130	13	GO:0051276
GeneOntologyBiologicalProcess	establishment of protein localization to endoplasmic reticulum	SRP68 SRPRB MACF1 SEC63	4.29e-04	56	130	4	GO:0072599
GeneOntologyBiologicalProcess	protein-DNA complex disassembly	HMGA1 ATAD2 SMARCC2	4.49e-04	24	130	3	GO:0032986
GeneOntologyCellularComponent	chromatin	SP4 ARID4B ARID4A JADE3 ZC3H8 CENPS BRD3 HMGA1 DPF2 MLXIP ZC3H6 WDR43 MEOX1 HOXA10 RIF1 KAT2B ARID1B OTX1 PHF20L1 MKX SMARCC2 MGA NIPBL HDAC1	1.68e-05	1480	132	24	GO:0000785
GeneOntologyCellularComponent	nBAF complex	DPF2 ARID1B SMARCC2	1.30e-04	16	132	3	GO:0071565
GeneOntologyCellularComponent	nuclear protein-containing complex	ELOA2 ARID4B ARID4A ZCCHC8 ZC3H8 SYNE1 CENPS HMGA1 DPF2 MLXIP ARID1B WBP4 KMT2A SMARCC2 PRPF19 TNKS ZNF830 MGA NIPBL MED13 HDAC1	1.45e-04	1377	132	21	GO:0140513
GeneOntologyCellularComponent	Sin3-type complex	ARID4B ARID4A HDAC1	3.47e-04	22	132	3	GO:0070822
HumanPheno	Postnatal growth retardation	NEXMIF SYNE1 DPF2 SMOC1 ARID1B KMT2A SMARCC2 PLCB4 NIPBL	2.52e-05	258	33	9	HP:0008897
Domain	Tudor	ARID4B ARID4A TDRD1 PHF20L1 TDRD12	2.02e-06	30	132	5	IPR002999
Domain	TUDOR	ARID4B ARID4A TDRD1 PHF20L1	3.69e-05	27	132	4	SM00333
Domain	RBB1NT	ARID4B ARID4A	4.96e-05	2	132	2	PF08169
Domain	RBB1NT	ARID4B ARID4A	4.96e-05	2	132	2	IPR012603
Domain	SPEC	AKAP6 KALRN SYNE1 MACF1	7.35e-05	32	132	4	SM00150
Domain	Spectrin/alpha-actinin	AKAP6 KALRN SYNE1 MACF1	7.35e-05	32	132	4	IPR018159
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH2 DNAH7	1.19e-04	14	132	3	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH2 DNAH7	1.19e-04	14	132	3	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH2 DNAH7	1.19e-04	14	132	3	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH2 DNAH7	1.19e-04	14	132	3	PF08393
Domain	MT	DYNC2H1 DNAH2 DNAH7	1.19e-04	14	132	3	PF12777
Domain	AAA_8	DYNC2H1 DNAH2 DNAH7	1.19e-04	14	132	3	PF12780
Domain	DHC_fam	DYNC2H1 DNAH2 DNAH7	1.48e-04	15	132	3	IPR026983
Domain	-	ARID4B ARID4A ARID1B	1.48e-04	15	132	3	1.10.150.60
Domain	BRIGHT	ARID4B ARID4A ARID1B	1.48e-04	15	132	3	SM00501
Domain	ARID_dom	ARID4B ARID4A ARID1B	1.48e-04	15	132	3	IPR001606
Domain	ARID	ARID4B ARID4A ARID1B	1.48e-04	15	132	3	PS51011
Domain	Dynein_heavy	DYNC2H1 DNAH2 DNAH7	1.48e-04	15	132	3	PF03028
Domain	ARID	ARID4B ARID4A ARID1B	1.48e-04	15	132	3	PF01388
Domain	Dynein_heavy_dom	DYNC2H1 DNAH2 DNAH7	1.48e-04	15	132	3	IPR004273
Domain	AT_hook	HMGA1 KMT2A DOT1L	1.81e-04	16	132	3	PF02178
Domain	BROMODOMAIN_2	BRD3 ATAD2 KAT2B KMT2A	1.97e-04	41	132	4	PS50014
Domain	Bromodomain	BRD3 ATAD2 KAT2B KMT2A	2.17e-04	42	132	4	IPR001487
Domain	BROMO	BRD3 ATAD2 KAT2B KMT2A	2.17e-04	42	132	4	SM00297
Domain	-	BRD3 ATAD2 KAT2B KMT2A	2.17e-04	42	132	4	1.20.920.10
Domain	DNAJ_1	GAK DNAJC6 SACS SEC63	3.95e-04	49	132	4	PS00636
Domain	DNAJ_2	GAK DNAJC6 SACS SEC63	3.95e-04	49	132	4	PS50076
Domain	DnaJ	GAK DNAJC6 SACS SEC63	3.95e-04	49	132	4	SM00271
Domain	-	GAK DNAJC6 SACS SEC63	3.95e-04	49	132	4	1.10.287.110
Domain	DnaJ_domain	GAK DNAJC6 SACS SEC63	4.61e-04	51	132	4	IPR001623
Domain	HnRNP-L/PTB	PTBP3 PTBP1	4.89e-04	5	132	2	IPR006536
Domain	Spectrin	KALRN SYNE1 MACF1	5.51e-04	23	132	3	PF00435
Domain	TUDOR	TDRD1 PHF20L1 TDRD12	5.51e-04	23	132	3	PS50304
Domain	Tudor-knot	ARID4B ARID4A	7.30e-04	6	132	2	PF11717
Domain	Tudor-knot	ARID4B ARID4A	7.30e-04	6	132	2	IPR025995
Domain	AT_hook	HMGA1 KMT2A DOT1L	8.91e-04	27	132	3	SM00384
Domain	AT_hook_DNA-bd_motif	HMGA1 KMT2A DOT1L	8.91e-04	27	132	3	IPR017956
Domain	C2_dom	GAK RAB11FIP2 DNAJC6 PLCB4 PLCL1 SEC63	1.10e-03	164	132	6	IPR000008
Domain	Spectrin_repeat	KALRN SYNE1 MACF1	1.10e-03	29	132	3	IPR002017
Domain	PTEN_C2	GAK DNAJC6	1.35e-03	8	132	2	PF10409
Domain	DHC_N1	DYNC2H1 DNAH2	1.35e-03	8	132	2	PF08385
Domain	PTEN_C2	GAK DNAJC6	1.35e-03	8	132	2	SM01326
Domain	C2_TENSIN	GAK DNAJC6	1.35e-03	8	132	2	PS51182
Domain	Tensin_lipid_phosphatase_dom	GAK DNAJC6	1.35e-03	8	132	2	IPR029023
Domain	Tensin_C2-dom	GAK DNAJC6	1.35e-03	8	132	2	IPR014020
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH2	1.35e-03	8	132	2	IPR013594
Domain	Chromo/shadow_dom	ARID4B ARID4A SMARCC2	1.61e-03	33	132	3	IPR000953
Domain	CHROMO	ARID4B ARID4A SMARCC2	1.61e-03	33	132	3	SM00298
Domain	PPASE_TENSIN	GAK DNAJC6	1.73e-03	9	132	2	PS51181
Domain	BROMODOMAIN_1	BRD3 ATAD2 KAT2B	2.25e-03	37	132	3	PS00633
Domain	Bromodomain	BRD3 ATAD2 KAT2B	2.43e-03	38	132	3	PF00439
Domain	KRAB_RELATED	SSX8P SSX5	2.62e-03	11	132	2	PS50806
Domain	AAA	DYNC2H1 DNAH2 ATAD2 DNAH7 MCM9	3.59e-03	144	132	5	SM00382
Domain	AAA+_ATPase	DYNC2H1 DNAH2 ATAD2 DNAH7 MCM9	3.59e-03	144	132	5	IPR003593
Domain	Krueppel-associated_box-rel	SSX8P SSX5	3.67e-03	13	132	2	IPR003655
Domain	-	ELOA2 HDGFL2	3.67e-03	13	132	2	1.20.930.10
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH2	4.27e-03	14	132	2	IPR011704
Domain	TFIIS_N	ELOA2 HDGFL2	4.27e-03	14	132	2	IPR017923
Domain	TUDOR	TDRD1 TDRD12	4.27e-03	14	132	2	PF00567
Domain	AAA_5	DYNC2H1 DNAH2	4.27e-03	14	132	2	PF07728
Domain	DnaJ	GAK DNAJC6 SEC63	4.73e-03	48	132	3	PF00226
Domain	ZF_PHD_1	JADE3 DPF2 PHF20L1 KMT2A	4.80e-03	96	132	4	PS01359
Domain	EF-hand_like	PLCB4 PLCL1	4.90e-03	15	132	2	PF09279
Domain	PI-PLC-Y	PLCB4 PLCL1	4.90e-03	15	132	2	PF00387
Domain	PLCYc	PLCB4 PLCL1	4.90e-03	15	132	2	SM00149
Domain	PLipase_C_Pinositol-sp_Y	PLCB4 PLCL1	4.90e-03	15	132	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCB4 PLCL1	4.90e-03	15	132	2	PS50008
Domain	PI-PLC_fam	PLCB4 PLCL1	4.90e-03	15	132	2	IPR001192
Domain	PLC_EF-hand-like	PLCB4 PLCL1	4.90e-03	15	132	2	IPR015359
Domain	PI-PLC-X	PLCB4 PLCL1	7.04e-03	18	132	2	PF00388
Domain	PLCXc	PLCB4 PLCL1	7.04e-03	18	132	2	SM00148
Pathway	KEGG_MEDICUS_VARIANT_MLL_AF4_FUSION_TO_TRANSCRIPTIONAL_ACTIVATION	BMP2K HOXA10 KMT2A DOT1L	2.37e-05	26	93	4	M47439
Pathway	REACTOME_EPIGENETIC_REGULATION_OF_GENE_EXPRESSION	ARID4B ZCCHC8 DPF2 KAT2B ARID1B PHF20L1 KMT2A SMARCC2 HDAC1	4.47e-05	254	93	9	M27131
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	ARID4B ARID4A JADE3 KAT2B ARID1B KMT2A SMARCC2 DOT1L HDAC1	7.59e-05	272	93	9	M29619
Pathway	REACTOME_CHROMATIN_MODIFYING_ENZYMES	ARID4B ARID4A JADE3 KMT2A SMARCC2 DOT1L HDAC1	1.56e-04	175	93	7	MM14941
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM15 ARID4B TCOF1 ARID4A JADE3 ZCCHC8 CARMIL1 CAST BRD3 HMGA1 DPF2 GPATCH8 RRBP1 ATAD2 TBC1D9 RIF1 SAFB TRAFD1 KMT2A SMARCC2 LIMCH1 ZNF579 NOP2 CCDC86 NIPBL MED13 PHLDB2	3.64e-18	774	136	27	15302935
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PTBP3 RBM15 TCOF1 KALRN RPLP2 WDR7 ZCCHC8 ZC3H8 SYNE1 RCN2 SRP68 BRD3 HMGA1 DPF2 GPATCH8 PTBP1 ZC3H6 ARID1B SAFB SACS SCG3 MKX SMARCC2 MACF1 PRPF19 SEC63 CCDC86 NIPBL	1.65e-15	1082	136	28	38697112
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RBM15 ARID4B TCOF1 RPLP2 ARID4A JADE3 ZCCHC8 ZC3H8 CENPS BRD3 HMGA1 GPATCH8 MLXIP PTBP1 RRBP1 SRPRB WDR43 HOXA10 RIF1 OTX1 SAFB KMT2A PRPF19 MGA NOP2 CCDC86 HDGFL2 NIPBL HDAC1	1.91e-14	1294	136	29	30804502
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	ZCCHC9 ARID4B ARID4A JADE3 BRD3 GPATCH8 ATAD2 WDR43 HOXA10 RIF1 PHF20L1 ZNF483 KMT2A SMARCC2 DOT1L MGA NOP2 CCDC86 HDGFL2 NIPBL HDAC1	3.33e-14	608	136	21	36089195
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM15 ARID4B ARID4A CAST ZDBF2 HMGA1 PTBP1 RRBP1 WDR43 NDUFV3 RIF1 ARID1B SAFB WBP4 KMT2A SMARCC2 PRPF19 ZNF830 MGA NOP2 CCDC86 HDGFL2 NIPBL	3.12e-12	954	136	23	36373674
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	PTBP3 ELOA2 ACACB SYNE1 DNAH2 TWNK BRD3 AHCYL2 HMGA1 PTBP1 RRBP1 MYLK2 GPALPP1 SAFB PHF20L1 SACS SCG3 KMT2A SMARCC2 MACF1 PRPF19 LIMCH1 POLQ HDGFL2 NIPBL MED13 HDAC1	1.12e-11	1442	136	27	35575683
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZCCHC9 BMP2K ZCCHC8 SYNE1 NACA RCN2 SRP68 TWNK BRD3 GPATCH8 ATAD2 MYLK2 WDR43 RIF1 ZNF800 PTCD1 NMT2 KMT2A MACF1 LIMCH1 ZNF579 SEC63 CCDC86 HDGFL2 NIPBL MED13 HDAC1	2.61e-11	1497	136	27	31527615
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RBM15 TCOF1 RPLP2 SYNE1 NACA HMGA1 PTBP1 RRBP1 SRPRB WDR43 RIF1 SAFB IGF2R SACS SMARCC2 MACF1 PRPF19 MGA NOP2 CCDC86 NIPBL PHLDB2	8.85e-11	1024	136	22	24711643
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZXDC SP4 ZC3H8 ZNF300 CTDSP1 BRD3 HMGA1 DZIP1 DPF2 ATAD2 ZC3H6 RIF1 KAT2B OTX1 PHF20L1 WBP4 MKX ZNF830 MGA	4.36e-10	808	136	19	20412781
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	BRD3 ATAD2 DNAH7 KAT2B SAFB PHF20L1 KMT2A HDAC1	6.01e-10	75	136	8	25593309
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GAK ACACB TCOF1 ZCCHC8 CARMIL1 NACA CAST SRP68 HMGA1 RRBP1 WDR43 GPALPP1 RIF1 SAFB KMT2A MACF1 PRPF19 NOP2 HDGFL2 NIPBL	7.34e-10	934	136	20	33916271
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	RBM15 TCOF1 RPLP2 NACA CENPS HMGA1 PTBP1 ATAD2 NDUFV3 RIF1 SAFB SMARCC2 PRPF19 NOP2 CCDC86 NIPBL HDAC1	8.29e-10	652	136	17	31180492
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RBM15 ARID4B ARID4A JADE3 SRP68 BRD3 DPF2 ATAD2 GPALPP1 KAT2B CCDC66 KMT2A MPHOSPH9 NOP2 CCDC86 MED13	5.45e-09	645	136	16	25281560
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	ARID4B ARID4A DPF2 ARID1B PHF20L1 SMARCC2 HDGFL2 NIPBL HDAC1	8.52e-09	150	136	9	28242625
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RBM15 TCOF1 KALRN RPLP2 ZCCHC8 RRBP1 WDR43 RIF1 SAFB TRAFD1 ZNF579 NOP2 NIPBL PHLDB2	1.24e-08	503	136	14	16964243
Pubmed	Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover.	RPLP2 NACA GPATCH8 RRBP1 GPALPP1 OTX1 SAFB IGF2R WBP4 KMT2A SMARCC2 HDGFL2 NIPBL	1.40e-08	425	136	13	24999758
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	RBM15 GAK ACAA1 TCOF1 NACA PTBP1 RRBP1 SAFB SNCAIP MACF1 ZNF579 NIPBL	2.03e-08	360	136	12	33111431
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RBM15 TCOF1 RPLP2 DYNC2H1 SYNE1 NACA RCN2 SRP68 PTBP1 RRBP1 ATAD2 SRPRB WDR43 RIF1 SAFB IGF2R PRPF19 SEC63 NOP2 CCDC86 NIPBL HDAC1	3.73e-08	1425	136	22	30948266
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBM15 TCOF1 RPLP2 ZCCHC8 SRP68 TWNK BRD3 ATAD2 RIF1 SAFB KMT2A SMARCC2 PRPF19 DOT1L NOP2 CCDC86 HDAC1	3.93e-08	847	136	17	35850772
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RBM15 TCOF1 RPLP2 ZCCHC8 SRP68 ATAD2 WDR43 RIF1 IGF2R KMT2A SMARCC2 MACF1 NOP2 CCDC86 NIPBL	4.62e-08	653	136	15	22586326
Pubmed	BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.	PTBP3 RBM15 ACACB BMP2K TCOF1 RPLP2 NACA CGAS SRP68 PTBP1 RRBP1 SRPRB WDR43 GPALPP1 SAFB KMT2A PRPF19 SEC63 NOP2 NIPBL HDAC1	4.65e-08	1318	136	21	30463901
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RBM15 RPLP2 KIF26B ZCCHC8 CARMIL1 RAB11FIP2 USP43 DZIP1 MLXIP DNAH7 MYLK2 RUSC2 KMT2A MACF1 LIMCH1 MPHOSPH9 PHLDB2	4.97e-08	861	136	17	36931259
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	RBM15 ARID4B TCOF1 RPLP2 ZC3H8 NACA CAST RCN2 SRP68 DPF2 PTBP1 RRBP1 KAT2B TRAFD1 PRPF19 SEC63 NOP2 HDAC1	5.03e-08	971	136	18	33306668
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM15 ZCCHC9 ARID4B NACA SRP68 TWNK PTBP1 RRBP1 WDR43 RIF1 MCM9 MACF1 PRPF19 NOP2 CCDC86 HDAC1	5.21e-08	759	136	16	35915203
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RBM15 RPLP2 NACA CGAS SRP68 HMGA1 DPF2 PTBP1 RRBP1 ATAD2 SRPRB RIF1 SAFB SMARCC2 MACF1 PRPF19 MGA NOP2 CCDC86 NIPBL PHLDB2	7.22e-08	1353	136	21	29467282
Pubmed	Interaction network of human early embryonic transcription factors.	ARID4B ACACB ARID4A DPF2 KAT2B ARID1B KMT2A SMARCC2 MGA NIPBL HDAC1	1.50e-07	351	136	11	38297188
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	PTBP3 RBM15 ZCCHC9 ZC3H8 SRP68 HMGA1 PTBP1 NDUFV3 PTCD1 WBP4 SMARCC2 PRPF19 ZNF830 SEC63 NOP2	1.71e-07	723	136	15	34133714
Pubmed	Human transcription factor protein interaction networks.	ARID4B ACACB ARID4A NACA RCN2 SRP68 TWNK DPF2 GPATCH8 HOXA10 RIF1 KAT2B ARID1B KMT2A SMARCC2 PRPF19 DOT1L MGA NOP2 CCDC86 NIPBL	1.79e-07	1429	136	21	35140242
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	JADE3 RCN2 BRD3 DPF2 ATAD2 RIF1 ZNF800 KMT2A SMARCC2 MGA CCDC86 NIPBL HDAC1	1.94e-07	533	136	13	30554943
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RBM15 BMP2K TCOF1 RPLP2 SYNE1 NACA SRP68 HMGA1 PTBP1 RRBP1 WDR43 SAFB PRPF19 LIMCH1 NOP2 CCDC86 HDAC1	1.98e-07	949	136	17	36574265
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	BMP2K TCOF1 RPLP2 GPATCH8 PTBP1 SRPRB TMEM38B RIF1 ZNF800 ARID1B OTX1 SAFB IGF2R SLC39A6 SMARCC2 TNKS SEC63 MGA NOP2	2.48e-07	1203	136	19	29180619
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	GAK TCOF1 RPLP2 DYNC2H1 SYNE1 RCN2 TWNK DZIP1 RRBP1 DNAJC6 SRPRB NDUFV3 IGF2R SACS PTCD1 SLC39A6 MACF1 PRPF19 SEC63 NOP2 HDGFL2	3.44e-07	1487	136	21	33957083
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	PTBP3 RBM15 TCOF1 NACA RCN2 SRP68 HMGA1 PTBP1 SMOC1 RRBP1 SRPRB WDR43 RIF1 KMT2A SMARCC2 PRPF19 LIMCH1 SEC63 NOP2 CCDC86	4.08e-07	1371	136	20	36244648
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	ACACB BMP2K TCOF1 RPLP2 WDR7 BSDC1 SRP68 PTBP1 DNAH7 SRPRB RIF1 IGF2R MPHOSPH9 MGA NOP2	4.27e-07	777	136	15	35844135
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	TCOF1 RPLP2 ZC3H8 NACA RCN2 SRP68 TWNK AHCYL2 PTBP1 DNAH7 ARID1B IGF2R SMARCC2 MACF1 PRPF19 POLQ AKAP7 HDAC1	6.26e-07	1153	136	18	29845934
Pubmed	ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.	ARID4B ARID4A JADE3 SMARCC2 HDAC1	6.43e-07	42	136	5	16387653
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	PTBP3 RBM15 TCOF1 ZC3H8 SYNE1 GPATCH8 PTBP1 RRBP1 NDUFV3 SAFB PTCD1 MACF1 ZNF579 NOP2 CCDC86	6.86e-07	807	136	15	22681889
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	GAK ARID4B ARID4A DNAJC6 ZC3H6 KAT2B ARID1B KMT2A	7.56e-07	186	136	8	33637726
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PDE1C GAK KALRN WDR7 SYNE1 CARMIL1 SRP68 PTBP1 RRBP1 DNAJC6 PNMA8B SAFB SACS NMT2 KMT2A SMARCC2 MACF1 PRPF19 LIMCH1 PLCL1	7.95e-07	1431	136	20	37142655
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	RBM15 TCOF1 RPLP2 ZCCHC8 SRP68 PTBP1 SAFB KMT2A SMARCC2 PRPF19 NOP2 HDGFL2 HDAC1	8.07e-07	605	136	13	28977666
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	RBM15 RPLP2 NACA SRP68 HMGA1 PTBP1 RRBP1 SRPRB KMT2A MACF1 PRPF19 NOP2 HDGFL2 HDAC1	8.41e-07	711	136	14	33022573
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	TCOF1 RPLP2 NACA SRP68 DPF2 PTBP1 RRBP1 ARID1B SAFB SMARCC2 PRPF19 NOP2 HDAC1	9.68e-07	615	136	13	31048545
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RBM15 TCOF1 RPLP2 ZCCHC8 NACA SRP68 HMGA1 PTBP1 WDR43 SAFB PRPF19 ZNF830 NOP2 CCDC86	1.16e-06	731	136	14	29298432
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	GAK NACA RCN2 SRP68 ZDBF2 GPATCH8 RRBP1 TMEM38B ARID1B IGF2R WBP4 MPHOSPH9 SEC63 MGA	1.20e-06	733	136	14	34672954
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TCOF1 KALRN WDR7 SYNE1 DNAJC6 IGF2R SMARCC2 DGKI MACF1 TNKS LIMCH1 PLCL1 MGA NOP2 NIPBL PHLDB2	1.24e-06	963	136	16	28671696
Pubmed	Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.	RBM15 ZDBF2 PTBP1 RIF1 PRPF19 MGA NOP2 NIPBL MED13	1.35e-06	272	136	9	31010829
Pubmed	A protein interaction landscape of breast cancer.	GAK BMP2K TCOF1 SRP68 DPF2 GPATCH8 RRBP1 ARID1B IGF2R MCM9 SMARCC2 MACF1 NOP2	1.36e-06	634	136	13	34591612
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	RBM15 TCOF1 NACA HMGA1 PTBP1 HOXA10 SAFB MGA NOP2 HDGFL2 HDAC1	1.42e-06	441	136	11	31239290
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ELOA2 ARID4B ACACB DYNC2H1 DNAH2 SRP68 ZDBF2 DPF2 DNAH7 ARID1B WBP4 SMARCC2 NIPBL	1.45e-06	638	136	13	31182584
Pubmed	Oct4 links multiple epigenetic pathways to the pluripotency network.	TCOF1 NACA SRP68 BRD3 DPF2 RIF1 SMARCC2 HDAC1	1.46e-06	203	136	8	22083510
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	RBM15 TCOF1 WDR7 DYNC2H1 SYNE1 NACA DNAH2 SRP68 PTBP1 ADGB LIMCH1 SEC63 MGA NOP2	1.67e-06	754	136	14	35906200
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RBM15 TCOF1 RPLP2 ZCCHC8 ZC3H8 GPATCH8 PTBP1 ATAD2 WDR43 RIF1 SAFB SMARCC2 PRPF19 SEC63 NOP2 CCDC86	1.75e-06	989	136	16	36424410
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ARID4B TCOF1 ZCCHC8 RCN2 BRD3 DPF2 HOXA10 KAT2B ARID1B ARHGEF33 TRAFD1 SMARCC2 MACF1 ZNF579 MGA PHLDB2 HDAC1	1.83e-06	1116	136	17	31753913
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	RBM15 NACA RCN2 SRP68 PTBP1 RIF1 SAFB NMT2 WBP4 PRPF19 SEC63 NOP2 HDAC1	1.88e-06	653	136	13	33742100
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PTBP3 RBM15 ACAA1 TCOF1 RPLP2 RCN2 SRP68 PTBP1 RRBP1 ZC3H6 SMARCC2 PRPF19 LIMCH1 DOT1L MGA MED13 PHLDB2 HDAC1	1.90e-06	1247	136	18	27684187
Pubmed	RNA Binding Protein Ptbp2 Is Essential for Male Germ Cell Development.	WDR7 DZIP1 PTBP1	2.02e-06	7	136	3	26391954
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	TCOF1 RPLP2 CARMIL1 NACA CAST SRP68 AHCYL2 HMGA1 PTBP1 RRBP1 SRPRB RIF1 SMARCC2 MACF1 PRPF19 NOP2 CCDC86 HDGFL2 NIPBL	2.77e-06	1415	136	19	28515276
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	GAK BMP2K JADE3 RCN2 GPATCH8 ANKRD36C RRBP1 SRPRB NDUFV3 NMT2 KMT2A ANKRD36 HDGFL2 AKAP7 HDAC1	3.01e-06	910	136	15	36736316
Pubmed	Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.	DPF2 ARID1B SMARCC2 HDAC1	3.13e-06	26	136	4	10778858
Pubmed	Identification and characterization of three new components of the mSin3A corepressor complex.	ARID4B ARID4A HDAC1	3.23e-06	8	136	3	12724404
Pubmed	NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.	TCOF1 ZCCHC8 BRD3 GPATCH8 KMT2A HDAC1	3.35e-06	103	136	6	32744500
Pubmed	The protein interaction landscape of the human CMGC kinase group.	RBM15 MARCHF10 TCOF1 ZCCHC8 BRD3 AHCYL2 GPATCH8 PTBP1 TRAFD1 NOP2 CCDC86 MED13 JHY	3.70e-06	695	136	13	23602568
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	KALRN SYNE1 DNAH2 AKNA DNAH7 RIF1 MCM9 TPH2	4.05e-06	233	136	8	37704626
Pubmed	REST repression of neuronal genes requires components of the hSWI.SNF complex.	DPF2 ARID1B SMARCC2 HDAC1	4.26e-06	28	136	4	12192000
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RBM15 ACACB CARMIL1 BRD3 RRBP1 SRPRB TRAFD1 KMT2A PLCB4 LIMCH1 HDGFL2	4.45e-06	497	136	11	36774506
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	ZCCHC8 DPF2 RIF1 SMARCC2 MGA MED13 HDAC1	4.50e-06	167	136	7	20362541
Pubmed	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	PTBP3 ACACB TCOF1 ARID4A DNAH2 HMGA1 PTBP1 RRBP1 PRPF19	4.71e-06	317	136	9	30997501
Pubmed	Coffin-Siris Syndrome	DPF2 ARID1B SMARCC2	4.83e-06	9	136	3	23556151
Pubmed	Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.	ARID4B ARID4A GPATCH8 TRAFD1 KMT2A HDAC1	4.91e-06	110	136	6	26841866
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	SYNE1 RCN2 SRP68 ATAD2 PRPF19 NOP2 MED13 PHLDB2 HDAC1	5.21e-06	321	136	9	32098917
Pubmed	Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.	ACACB RPLP2 CGAS RCN2 HMGA1 PTBP1 SAFB NOP2	5.69e-06	244	136	8	30349055
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	PTBP3 ZCCHC8 GPATCH8 PTBP1 RIF1 SAFB SMARCC2 PRPF19	5.69e-06	244	136	8	29884807
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	PDE1C ACACB TCOF1 RPLP2 CTDSP1 HMGA1 GPATCH8 DNAH7 TRAFD1 HDAC1	6.52e-06	420	136	10	28065597
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ACACB CARMIL1 RAB11FIP2 CTDSP1 DZIP1 IGF2R SLC39A6 MACF1 SEC63 PHLDB2	6.66e-06	421	136	10	36976175
Pubmed	Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner.	ARID1B KMT2A SMARCC2	6.88e-06	10	136	3	12665591
Pubmed	Nomenclature of the ARID family of DNA-binding proteins.	ARID4B ARID4A ARID1B	6.88e-06	10	136	3	15922553
Pubmed	Sf3b4 regulates chromatin remodeler splicing and Hox expression.	HOXA10 KAT2B PHF20L1 KMT2A	7.39e-06	32	136	4	37167859
Pubmed	The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.	BMP2K ARID1B SLC39A6 SMARCC2	8.38e-06	33	136	4	19336002
Pubmed	Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.	PTBP1 KAT2B MGA HDGFL2 NIPBL HDAC1	9.79e-06	124	136	6	20850016
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ACACB KALRN RAB11FIP2 NACA BSDC1 ZDBF2 AHCYL2 HMGA1 PTBP1 RRBP1 SRPRB SAFB SLC39A6 SMARCC2 MACF1 AKAP7	1.04e-05	1139	136	16	36417873
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RBM15 ACACB ZCCHC8 RAB11FIP2 RCN2 DPF2 SRPRB ARID1B MPHOSPH9 PHLDB2	1.10e-05	446	136	10	24255178
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	ZCCHC8 DPF2 ARID1B KMT2A SMARCC2 MGA NIPBL MED13	1.13e-05	268	136	8	33640491
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	NACA SRP68 PTBP1 RRBP1 SRPRB TMEM38B TBC1D9 RIF1 IGF2R TRAFD1 SEC63 MGA	1.13e-05	657	136	12	36180527
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	AKAP6 TCOF1 KALRN ZCCHC8 SYNE1 CTDSP1 NCKAP5 DZIP1 RRBP1 SACS SCG3 NMT2 MACF1 TNKS ANKRD36 NIPBL MED13	1.17e-05	1285	136	17	35914814
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	RBM15 NACA CGAS WDR43 SAFB MACF1 PRPF19 NOP2 CCDC86 HDGFL2 PHLDB2 HDAC1	1.18e-05	660	136	12	32780723
Pubmed	NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.	PTBP3 PTBP1 RIF1 SMARCC2 PRPF19 HDAC1	1.23e-05	129	136	6	23022380
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	BRD3 HMGA1 DPF2 KMT2A SMARCC2 NOP2 HDAC1	1.24e-05	195	136	7	19454010
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GAK TCOF1 RPLP2 RCN2 SRP68 HMGA1 RRBP1 SRPRB IGF2R SMARCC2 MACF1 PRPF19 PLCB4 SEC63 CCDC86 NIPBL HDAC1	1.32e-05	1297	136	17	33545068
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	BMP2K TCOF1 NEXMIF SYNE1 GPATCH8 MACF1 TNKS	1.32e-05	197	136	7	20811636
Pubmed	Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.	DPF2 ARID1B SMARCC2 HDAC1	1.34e-05	37	136	4	24335282
Pubmed	The Guanine nucleotide exchange factor kalirin-7 is a novel synphilin-1 interacting protein and modifies synphilin-1 aggregate transport and formation.	KALRN SNCAIP	1.52e-05	2	136	2	23284848
Pubmed	Characterization of large-scale genomic differences in the first complete human genome.	KLRC2 KLRC3	1.52e-05	2	136	2	37403156
Pubmed	Distinct Responses to Menin Inhibition and Synergy with DOT1L Inhibition in KMT2A-Rearranged Acute Lymphoblastic and Myeloid Leukemia.	KMT2A DOT1L	1.52e-05	2	136	2	38892207
Pubmed	Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.	DOT1L HDAC1	1.52e-05	2	136	2	31304633
Pubmed	Interplay between DOT1L and HDAC1 regulates Leishmania donovani infection in human THP-1 cells.	DOT1L HDAC1	1.52e-05	2	136	2	39103111
Pubmed	HOXA10 promotion of HDAC1 underpins the development of lung adenocarcinoma through the DNMT1-KLF4 axis.	HOXA10 HDAC1	1.52e-05	2	136	2	33596966
Pubmed	Auxilin depletion causes self-assembly of clathrin into membraneless cages in vivo.	GAK DNAJC6	1.52e-05	2	136	2	18489706
Pubmed	MLL-rearranged leukemia is dependent on aberrant H3K79 methylation by DOT1L.	KMT2A DOT1L	1.52e-05	2	136	2	21741597
Pubmed	Identification of chromatin remodeling genes Arid4a and Arid4b as leukemia suppressor genes.	ARID4B ARID4A	1.52e-05	2	136	2	18728284
Pubmed	DOT1L inhibition sensitizes MLL-rearranged AML to chemotherapy.	KMT2A DOT1L	1.52e-05	2	136	2	24858818
Interaction	MECP2 interactions	PTBP3 RBM15 TCOF1 KALRN RPLP2 WDR7 ZCCHC8 ZC3H8 SYNE1 RCN2 SRP68 TWNK BRD3 HMGA1 DPF2 GPATCH8 PTBP1 ZC3H6 ZNF800 ARID1B SAFB SACS SCG3 ZNF483 MKX SMARCC2 MACF1 PRPF19 SEC63 NOP2 CCDC86 NIPBL HDAC1	1.42e-11	1287	135	33	int:MECP2
Interaction	SNRNP40 interactions	RBM15 ACACB TCOF1 JADE3 ZDBF2 GPATCH8 PTBP1 ATAD2 WDR43 GPALPP1 ARID1B PHF20L1 WBP4 KMT2A SMARCC2 PRPF19 ZNF830 DOT1L MGA HDGFL2	9.33e-09	637	135	20	int:SNRNP40
Interaction	MYCN interactions	RBM15 ZCCHC9 TCOF1 RPLP2 ZCCHC8 ZC3H8 SYNE1 NACA RCN2 SRP68 HMGA1 DPF2 GPATCH8 PTBP1 WDR43 KAT2B ARID1B SAFB PTCD1 WBP4 KMT2A SMARCC2 PRPF19 ZNF830 DOT1L NOP2 CCDC86 HDGFL2 HDAC1	2.54e-08	1373	135	29	int:MYCN
Interaction	H3C1 interactions	ARID4B DYNC2H1 SYNE1 NACA CAST DNAH2 BRD3 HMGA1 DPF2 RRBP1 ATAD2 MYLK2 RIF1 KAT2B KMT2A SMARCC2 ZNF830 MGA NOP2 HDGFL2 NIPBL HDAC1 JHY	3.10e-08	901	135	23	int:H3C1
Interaction	CSNK2A1 interactions	ARID4B TCOF1 ZCCHC8 ZC3H8 NACA BRD3 HMGA1 ANKRD36C ATAD2 MEOX1 KAT2B SAFB IGF2R SNCAIP NMT2 KMT2A SMARCC2 MACF1 PRPF19 ANKRD36 MGA HDGFL2 HDAC1	9.08e-08	956	135	23	int:CSNK2A1
Interaction	NUP43 interactions	RBM15 ARID4B ACACB ARID4A JADE3 ZDBF2 CCDC168 GPATCH8 ATAD2 WDR43 GPALPP1 RIF1 ARID1B SAFB PHF20L1 KMT2A MGA NIPBL	2.00e-07	625	135	18	int:NUP43
Interaction	SMC5 interactions	RBM15 ARID4B ARID4A CAST ZDBF2 HMGA1 PTBP1 RRBP1 WDR43 NDUFV3 RIF1 ARID1B SAFB WBP4 KMT2A SMARCC2 PRPF19 ZNF830 MGA NOP2 CCDC86 HDGFL2 NIPBL	2.03e-07	1000	135	23	int:SMC5
Interaction	H3C3 interactions	ZCCHC9 ARID4A JADE3 BRD3 ATAD2 WDR43 HOXA10 RIF1 KMT2A SMARCC2 MGA NOP2 CCDC86 HDGFL2 NIPBL HDAC1	2.17e-07	495	135	16	int:H3C3
Interaction	H3-4 interactions	JADE3 ZC3H8 RAB11FIP2 HMGA1 DPF2 PTBP1 ATAD2 MYLK2 ZNF800 KAT2B KMT2A DOT1L MGA NOP2 HDAC1	3.41e-07	448	135	15	int:H3-4
Interaction	CIT interactions	PTBP3 RBM15 TCOF1 KALRN RPLP2 DYNC2H1 SYNE1 NACA CGAS RCN2 SRP68 BRD3 HMGA1 PTBP1 WDR43 RIF1 SAFB PTCD1 KMT2A SMARCC2 MACF1 PRPF19 NOP2 CCDC86 HDGFL2 NIPBL HDAC1	1.03e-06	1450	135	27	int:CIT
Interaction	CHD4 interactions	RBM15 TCOF1 RPLP2 ZCCHC8 USP43 SRP68 BRD3 HMGA1 DPF2 GPATCH8 PTBP1 RRBP1 SAFB PHF20L1 KMT2A SMARCC2 PRPF19 DOT1L NOP2 HDGFL2 HDAC1	1.13e-06	938	135	21	int:CHD4
Interaction	H2BC8 interactions	ARID4B ARID4A JADE3 BRD3 HMGA1 DPF2 ATAD2 WDR43 GPALPP1 RIF1 KMT2A SMARCC2 MGA CCDC86 HDGFL2 NIPBL	1.61e-06	576	135	16	int:H2BC8
Interaction	NAA40 interactions	GAK ACACB TCOF1 ZCCHC8 CARMIL1 NACA CAST SRP68 HMGA1 RRBP1 WDR43 GPALPP1 RIF1 SAFB KMT2A MACF1 PRPF19 LIMCH1 NOP2 HDGFL2 NIPBL	2.20e-06	978	135	21	int:NAA40
Interaction	H2AX interactions	ZCCHC9 ARID4B RPLP2 ARID4A NACA BRD3 HMGA1 DPF2 GPATCH8 KAT2B ARID1B PHF20L1 SMARCC2 CCDC86 HDGFL2 NIPBL	2.34e-06	593	135	16	int:H2AX
Interaction	H3-3A interactions	ARID4B BRD3 HMGA1 GPATCH8 ATAD2 MYLK2 HOXA10 RIF1 KAT2B PHF20L1 ZNF483 KMT2A SMARCC2 DOT1L MGA HDGFL2 NIPBL HDAC1	2.69e-06	749	135	18	int:H3-3A
Interaction	H2BC21 interactions	ARID4B ARID4A JADE3 CGAS DNAH2 HMGA1 DPF2 ATAD2 RIF1 KAT2B ARID1B KMT2A SMARCC2 NOP2 CCDC86 NIPBL HDAC1	4.21e-06	696	135	17	int:H2BC21
Interaction	CBX3 interactions	TCOF1 JADE3 RCN2 BRD3 HMGA1 ATAD2 WDR43 TGOLN2 RIF1 ZNF483 KMT2A MACF1 ZNF830 MGA HDGFL2 NIPBL	6.93e-06	646	135	16	int:CBX3
Interaction	BMI1 interactions	PTBP3 ACAA1 KIF26B ZCCHC8 SYNE1 TWNK DPF2 GPATCH8 PTBP1 RRBP1 TDRD1 KAT2B ZDHHC23 KMT2A MGA NOP2	8.89e-06	659	135	16	int:BMI1
Interaction	EN1 interactions	ARID4B TWNK AHCYL2 RIF1 KMT2A MGA NIPBL	9.28e-06	110	135	7	int:EN1
Interaction	WDR5 interactions	ZXDC RBM15 ACACB RPLP2 NACA SRP68 HMGA1 PTBP1 RRBP1 SRPRB KAT2B PHF20L1 KMT2A SMARCC2 MACF1 PRPF19 DOT1L MGA NOP2 HDGFL2 HDAC1	1.36e-05	1101	135	21	int:WDR5
Interaction	ETS1 interactions	ARID4B DPF2 KAT2B ARID1B SMARCC2 MGA HDAC1	1.73e-05	121	135	7	int:ETS1
Interaction	H2BC3 interactions	USP43 SRP68 BRD3 HMGA1 RRBP1 RIF1 KAT2B KMT2A SMARCC2 DOT1L CCDC86 HDAC1	1.89e-05	406	135	12	int:H2BC3
Interaction	CDK8 interactions	ARID4B HMGA1 RIF1 KAT2B SMARCC2 ZNF830 MGA NIPBL MED13	1.91e-05	222	135	9	int:CDK8
Interaction	MLLT1 interactions	ARID4B ARID4A ARID1B KMT2A SMARCC2 DOT1L HDGFL2	1.93e-05	123	135	7	int:MLLT1
Interaction	IRF1 interactions	HMGA1 DPF2 KAT2B ARID1B SEC63 MGA	2.00e-05	83	135	6	int:IRF1
Interaction	BRD7 interactions	PTBP3 NACA RCN2 BRD3 HMGA1 DPF2 GPATCH8 PTBP1 RRBP1 RIF1 ARID1B NMT2 SMARCC2 PRPF19 NOP2	2.46e-05	637	135	15	int:BRD7
Interaction	CSNK2A2 interactions	ARID4B TCOF1 JADE3 NACA BRD3 HMGA1 ANKRD36C NMT2 KMT2A PRPF19 ANKRD36 DOT1L MGA NOP2 HDGFL2 HDAC1	2.55e-05	718	135	16	int:CSNK2A2
Interaction	POLR1G interactions	ARID4B TCOF1 JADE3 ZCCHC8 BRD3 WDR43 KMT2A SMARCC2 DOT1L MGA NOP2 NIPBL HDAC1	2.56e-05	489	135	13	int:POLR1G
Interaction	ACTL6A interactions	ARID4B BRD3 HMGA1 DPF2 ARID1B SMARCC2 PRPF19 DOT1L HDGFL2 HDAC1	2.56e-05	289	135	10	int:ACTL6A
Interaction	PPIA interactions	RPLP2 DYNC2H1 NACA CAST SRP68 ANKRD36C RRBP1 GPALPP1 RIF1 ARID1B SAFB IGF2R WBP4 MACF1 PRPF19 ANKRD36 HDGFL2 HDAC1	2.72e-05	888	135	18	int:PPIA
Interaction	MBD3 interactions	ARID4B USP43 BRD3 DPF2 MEOX1 ZNF800 PHF20L1 KMT2A SMARCC2 HDAC1	3.05e-05	295	135	10	int:MBD3
Interaction	OBSL1 interactions	SELENOP RBM15 TCOF1 SYNE1 HMGA1 PTBP1 WDR43 RIF1 SAFB SMARCC2 MACF1 PRPF19 POLQ MGA NOP2 CCDC86 NIPBL PHLDB2	3.33e-05	902	135	18	int:OBSL1
Interaction	SP1 interactions	SP4 GAK ARID4B ARID4A RCN2 TWNK HMGA1 KAT2B KMT2A SMARCC2 HDAC1	3.57e-05	365	135	11	int:SP1
Interaction	PCNT interactions	AKAP6 KALRN SYNE1 RRBP1 DNAJC6 MACF1 MPHOSPH9 NIPBL HDAC1	3.64e-05	241	135	9	int:PCNT
Interaction	MAU2 interactions	ZDBF2 PTBP1 RIF1 PRPF19 MGA NIPBL MED13	3.69e-05	136	135	7	int:MAU2
Interaction	APEX1 interactions	ARID4B BMP2K TCOF1 ARID4A BRD3 HMGA1 WDR43 TGOLN2 RIF1 SAFB CCDC66 KMT2A SMARCC2 PRPF19 LIMCH1 MPHOSPH9 DOT1L MGA NOP2 HDGFL2 NIPBL HDAC1	3.69e-05	1271	135	22	int:APEX1
Interaction	SIRT7 interactions	RBM15 TCOF1 RPLP2 ZCCHC8 SRP68 ATAD2 WDR43 RIF1 KAT2B IGF2R KMT2A SMARCC2 MACF1 NOP2 CCDC86 NIPBL	3.91e-05	744	135	16	int:SIRT7
Interaction	SP7 interactions	ARID4B RCN2 DPF2 GPATCH8 HOXA10 KAT2B ARID1B SMARCC2 MGA NIPBL	3.94e-05	304	135	10	int:SP7
Interaction	HNF1B interactions	ARID4B TCOF1 DPF2 KAT2B ARID1B MGA NIPBL HDAC1	4.30e-05	190	135	8	int:HNF1B
Interaction	MYOD1 interactions	ARID4B DPF2 KAT2B ARID1B SMARCC2 MGA NIPBL HDAC1	4.98e-05	194	135	8	int:MYOD1
Interaction	TFCP2L1 interactions	ZCCHC8 DPF2 RIF1 SMARCC2 MGA HDAC1	5.44e-05	99	135	6	int:TFCP2L1
Interaction	NR2C2 interactions	PTBP3 RBM15 ACACB BMP2K TCOF1 RPLP2 NACA CGAS SRP68 PTBP1 RRBP1 SRPRB WDR43 TGOLN2 GPALPP1 SAFB KMT2A PRPF19 DOT1L SEC63 NOP2 NIPBL HDAC1	5.57e-05	1403	135	23	int:NR2C2
Interaction	KDM5B interactions	BMP2K ARID1B SLC39A6 KMT2A SMARCC2 HDAC1	5.75e-05	100	135	6	int:KDM5B
Interaction	E2F4 interactions	PTBP3 RBM15 HMGA1 ATAD2 ARID1B TRAFD1 KMT2A SMARCC2 PRPF19 MGA CCDC86 PHLDB2 HDAC1	7.06e-05	540	135	13	int:E2F4
Interaction	ASH2L interactions	JADE3 ZCCHC8 HMGA1 DPF2 SACS KMT2A DOT1L MGA HDAC1	7.59e-05	265	135	9	int:ASH2L
Interaction	EED interactions	RBM15 GAK ARID4B ACACB BMP2K TCOF1 RPLP2 SRP68 HMGA1 PTBP1 ATAD2 WDR43 RIF1 SAFB IGF2R SMARCC2 MACF1 PRPF19 LIMCH1 MGA NOP2 NIPBL HDAC1	8.71e-05	1445	135	23	int:EED
Interaction	EFTUD2 interactions	TCOF1 RPLP2 CARMIL1 NACA CAST SRP68 AHCYL2 HMGA1 PTBP1 RRBP1 SRPRB RIF1 WBP4 SMARCC2 MACF1 PRPF19 DOT1L NOP2 CCDC86 HDGFL2 NIPBL MED13 HDAC1	9.08e-05	1449	135	23	int:EFTUD2
Interaction	GCM1 interactions	ARID4B DPF2 ARID1B SMARCC2 HDAC1	9.30e-05	68	135	5	int:GCM1
Interaction	SRPK2 interactions	RBM15 MARCHF10 TCOF1 RPLP2 TWNK BRD3 HMGA1 GPATCH8 PTBP1 PNMA8B SAFB MACF1 DOT1L NOP2 CCDC86	9.41e-05	717	135	15	int:SRPK2
Interaction	DDX23 interactions	RBM15 TCOF1 JADE3 SYNE1 GPATCH8 PTBP1 WDR43 GPALPP1 SAFB WBP4 NOP2 HDGFL2	9.51e-05	480	135	12	int:DDX23
Interaction	TERF2 interactions	BMP2K TCOF1 NEXMIF SYNE1 BRD3 HMGA1 GPATCH8 MACF1 TNKS HDGFL2	1.00e-04	340	135	10	int:TERF2
Interaction	DOT1L interactions	RBM15 TCOF1 ZCCHC8 SRP68 TWNK BRD3 HMGA1 ATAD2 RIF1 SAFB KMT2A SMARCC2 DOT1L NOP2 CCDC86 HDAC1	1.02e-04	807	135	16	int:DOT1L
Interaction	VRK1 interactions	ACACB RPLP2 DNAH2 BRD3 HMGA1 PTBP1 TBC1D9 RIF1 PRPF19	1.06e-04	277	135	9	int:VRK1
Interaction	SNIP1 interactions	TCOF1 BRD3 GPATCH8 ATAD2 GPALPP1 ARID1B SMARCC2 PRPF19 NOP2 CCDC86 NIPBL	1.17e-04	417	135	11	int:SNIP1
Interaction	BRD3 interactions	JADE3 RCN2 BRD3 DPF2 ATAD2 RIF1 KMT2A SMARCC2 DOT1L MGA CCDC86 NIPBL	1.25e-04	494	135	12	int:BRD3
Interaction	LIN28A interactions	TCOF1 RPLP2 ZC3H8 SRP68 PTBP1 WDR43 PTCD1 PRPF19 DOT1L NOP2 CCDC86	1.28e-04	421	135	11	int:LIN28A
Interaction	TBXT interactions	ARID4B DPF2 ARID1B SMARCC2 DOT1L NIPBL	1.31e-04	116	135	6	int:TBXT
Interaction	GATAD2A interactions	ARID4B BRD3 DPF2 KAT2B PHF20L1 SMARCC2 DOT1L HDAC1	1.36e-04	224	135	8	int:GATAD2A
Interaction	BRD9 interactions	TCOF1 RCN2 BRD3 DPF2 ARID1B SMARCC2	1.38e-04	117	135	6	int:BRD9
Interaction	SMARCE1 interactions	BRD3 HMGA1 DPF2 TGOLN2 ARID1B SMARCC2 DOT1L HDGFL2 HDAC1	1.39e-04	287	135	9	int:SMARCE1
Interaction	NFATC1 interactions	HMGA1 DPF2 HOXA10 KAT2B SMARCC2 NIPBL HDAC1	1.40e-04	168	135	7	int:NFATC1
Interaction	NFIX interactions	ARID4B DPF2 ARID1B KMT2A SMARCC2 MGA NIPBL HDAC1	1.49e-04	227	135	8	int:NFIX
Interaction	NRIP1 interactions	AKAP6 KALRN NCKAP5 KAT2B SCG3 MACF1 HDAC1	1.50e-04	170	135	7	int:NRIP1
Interaction	POU5F1 interactions	ACACB TCOF1 ZCCHC8 NACA SRP68 BRD3 HMGA1 DPF2 RIF1 ARID1B SMARCC2 MGA HDAC1	1.54e-04	584	135	13	int:POU5F1
Interaction	EGR2 interactions	ARID4B DPF2 KAT2B ARID1B KMT2A MGA NIPBL	1.56e-04	171	135	7	int:EGR2
Interaction	DHX8 interactions	RBM15 AHCYL2 GPATCH8 GPALPP1 SAFB PRPF19 ZNF830 DOT1L NOP2	1.58e-04	292	135	9	int:DHX8
Interaction	RBBP7 interactions	ARID4B ACACB TCOF1 ARID4A USP43 HMGA1 SAFB PHF20L1 KMT2A SMARCC2 DOT1L HDAC1	1.59e-04	507	135	12	int:RBBP7
Interaction	CHD3 interactions	RBM15 ARID4B RPLP2 ZCCHC8 SRP68 PTBP1 RIF1 SAFB PHF20L1 KMT2A SMARCC2 PRPF19 DOT1L NOP2 HDAC1	1.71e-04	757	135	15	int:CHD3
Interaction	SMARCB1 interactions	ARID4B BRD3 HMGA1 DPF2 KAT2B ARID1B KMT2A SMARCC2 DOT1L HDAC1	1.74e-04	364	135	10	int:SMARCB1
Interaction	MEN1 interactions	RBM15 TCOF1 RPLP2 ZCCHC8 SRP68 TWNK ATAD2 RIF1 ARID1B SAFB PHF20L1 KMT2A SMARCC2 PRPF19 DOT1L NOP2 CCDC86 HDAC1	1.78e-04	1029	135	18	int:MEN1
Interaction	TEAD1 interactions	ARID4B CGAS DPF2 HOXA10 ARID1B MGA NIPBL	1.86e-04	176	135	7	int:TEAD1
Interaction	NFYC interactions	SP4 ARID4B KAT2B KMT2A ZNF830 MGA HDAC1	1.93e-04	177	135	7	int:NFYC
Interaction	CDC5L interactions	AKAP6 PTBP3 KALRN SYNE1 SRP68 ZDBF2 PTBP1 MYLK2 RIF1 SMARCC2 MACF1 PRPF19 ZNF830 DOT1L NOP2 NIPBL	1.97e-04	855	135	16	int:CDC5L
Interaction	PEX14 interactions	GAK ACACB DYNC2H1 SMARCC2 TNKS LIMCH1 MPHOSPH9 HDAC1	2.00e-04	237	135	8	int:PEX14
Interaction	SSRP1 interactions	RBM15 JADE3 ZCCHC8 BRD3 DPF2 RIF1 SAFB KMT2A PRPF19 ZNF830 DOT1L NOP2 HDGFL2 NIPBL	2.07e-04	685	135	14	int:SSRP1
Interaction	CHD1 interactions	CGAS BRD3 HMGA1 SAFB DOT1L HDAC1	2.15e-04	127	135	6	int:CHD1
Interaction	CENPA interactions	JADE3 BRD3 HMGA1 ATAD2 KMT2A DOT1L NOP2 HDGFL2 NIPBL HDAC1	2.31e-04	377	135	10	int:CENPA
Interaction	MXD1 interactions	ARID4B ARID4A MGA HDAC1	2.32e-04	45	135	4	int:MXD1
Interaction	KIF20A interactions	PTBP3 RPLP2 DYNC2H1 SYNE1 CGAS HMGA1 DPF2 PTBP1 WDR43 SAFB SMARCC2 MACF1 PRPF19 TNKS NOP2 CCDC86 PHLDB2 HDAC1	2.33e-04	1052	135	18	int:KIF20A
Interaction	LINC00839 interactions	RPLP2 SYNE1 CCDC168 PTBP1 RIF1	2.39e-04	83	135	5	int:LINC00839
Interaction	KCNA3 interactions	TCOF1 CARMIL1 NACA RCN2 SRP68 PTBP1 RRBP1 SRPRB IGF2R KMT2A MACF1 MPHOSPH9 SEC63 POLQ HDAC1 TDRD12	2.42e-04	871	135	16	int:KCNA3
Interaction	ZC3H18 interactions	RBM15 TCOF1 RPLP2 ZCCHC8 NACA SRP68 TWNK HMGA1 PTBP1 WDR43 SAFB PRPF19 ZNF830 DOT1L NOP2 CCDC86	2.62e-04	877	135	16	int:ZC3H18
Interaction	SMARCC1 interactions	ARID4B BRD3 HMGA1 DPF2 ARID1B OTX1 KMT2A SMARCC2 HDGFL2 HDAC1	2.67e-04	384	135	10	int:SMARCC1
Interaction	DHX40 interactions	RBM15 ZCCHC8 ZC3H8 ZDBF2 GPATCH8 SAFB MGA NOP2	2.79e-04	249	135	8	int:DHX40
Interaction	FBXO22 interactions	RBM15 ACACB CARMIL1 BRD3 RRBP1 SRPRB TGOLN2 TRAFD1 KMT2A PLCB4 LIMCH1 HDGFL2	2.83e-04	540	135	12	int:FBXO22
Interaction	ZMYND8 interactions	BRD3 DNAH7 SAFB PHF20L1 DOT1L MGA HDAC1	3.07e-04	191	135	7	int:ZMYND8
Interaction	TEX13B interactions	DPF2 ARID1B SMARCC2	3.08e-04	20	135	3	int:TEX13B
Interaction	SS18 interactions	BRD3 DPF2 ARID1B SMARCC2 HDAC1	3.14e-04	88	135	5	int:SS18
Interaction	NHLH1 interactions	ARID4B DPF2 KMT2A MGA NOP2	3.14e-04	88	135	5	int:NHLH1
Interaction	HECTD1 interactions	RBM15 ZCCHC9 ARID4B NACA SRP68 TWNK PTBP1 RRBP1 WDR43 TGOLN2 RIF1 MCM9 MACF1 PRPF19 NOP2 CCDC86 HDAC1	3.15e-04	984	135	17	int:HECTD1
Interaction	IFI16 interactions	RBM15 SYNE1 CGAS RCN2 SRP68 ATAD2 WDR43 SAFB SMARCC2 PRPF19 ZNF579 DOT1L NOP2 CCDC86	3.16e-04	714	135	14	int:IFI16
Interaction	NCSTN interactions	GSAP DPF2 SRPRB TGOLN2 SAFB SMARCC2 NOP2	3.17e-04	192	135	7	int:NCSTN
Interaction	KLF5 interactions	ARID4B DPF2 RRBP1 ARID1B MGA NIPBL HDAC1	3.48e-04	195	135	7	int:KLF5
Interaction	PRKRA interactions	PTBP3 TCOF1 RPLP2 CGAS SRP68 ZNF800 ZNF483 KMT2A NOP2 CCDC86	3.69e-04	400	135	10	int:PRKRA
Interaction	EWSR1 interactions	RPLP2 ZCCHC8 NACA HMGA1 GPATCH8 RRBP1 TGOLN2 GPALPP1 OTX1 SAFB IGF2R WBP4 KMT2A SMARCC2 HDGFL2 NIPBL	3.75e-04	906	135	16	int:EWSR1
Interaction	KCTD13 interactions	PDE1C GAK KALRN WDR7 SYNE1 CARMIL1 SRP68 TWNK AHCYL2 PTBP1 RRBP1 DNAJC6 PNMA8B SACS NMT2 KMT2A SMARCC2 MACF1 PRPF19 LIMCH1 PLCL1	3.86e-04	1394	135	21	int:KCTD13
Interaction	LGR4 interactions	GAK TCOF1 PTBP1 RRBP1 TGOLN2 SAFB KMT2A NOP2	3.92e-04	262	135	8	int:LGR4
Interaction	NANOG interactions	ACACB ZCCHC8 HMGA1 DPF2 GPATCH8 RIF1 ARID1B DOT1L MGA CCDC86 HDAC1	4.01e-04	481	135	11	int:NANOG
Interaction	NFKBIL1 interactions	BRD3 AHCYL2 GPATCH8 WDR43 HDGFL2	4.06e-04	93	135	5	int:NFKBIL1
Interaction	PHLPP1 interactions	RBM15 TCOF1 KIF26B NACA SRP68 ZDBF2 RRBP1 LIMCH1 HDAC1	4.16e-04	333	135	9	int:PHLPP1
GeneFamily	AT-rich interaction domain containing	ARID4B ARID4A ARID1B	5.73e-05	15	93	3	418
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	GAK DNAJC6 SACS SEC63	1.16e-04	49	93	4	584
GeneFamily	DNAJ (HSP40) heat shock proteins\|C2 tensin-type domain containing	GAK DNAJC6	7.18e-04	8	93	2	837
GeneFamily	Zinc fingers CCCH-type	ZC3H8 ZC3H11B ZC3H6	7.65e-04	35	93	3	73
GeneFamily	Tudor domain containing	TDRD1 PHF20L1 TDRD12	9.02e-04	37	93	3	780
GeneFamily	PHD finger proteins	JADE3 DPF2 PHF20L1 KMT2A	1.20e-03	90	93	4	88
GeneFamily	Ankyrin repeat domain containing	ANKRD13D ANKRD36C SNCAIP DGKI TNKS ANKRD36	1.56e-03	242	93	6	403
GeneFamily	CD molecules\|C-type lectin domain family\|Killer cell lectin like receptors	KLRC2 KLRC3	1.67e-03	12	93	2	621
GeneFamily	Dyneins, axonemal	DNAH2 DNAH7	3.39e-03	17	93	2	536
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCB4 PLCL1	4.23e-03	19	93	2	832
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	ZCCHC9 ARID4B ZC3H8 CAST RCN2 DZIP1 ATAD2 TBC1D9 GPALPP1 RIF1 PHF20L1 SACS WBP4 SLC39A6 SEC63 POLQ NIPBL	5.03e-08	656	135	17	M18979
Coexpression	GSE2197_IMMUNOSUPPRESSIVE_DNA_VS_UNTREATED_IN_DC_UP	ACAA1 ARID4A CGAS RCN2 HMGA1 GSAP WDR43 CCDC86 HDAC1	9.99e-07	200	135	9	M4387
Coexpression	LU_EZH2_TARGETS_DN	ANKRD13D ZCCHC9 JADE3 RAB11FIP2 ANKRD36C TDRD1 OTX1 ZNF483 LIMCH1 SEC63 POLQ	7.52e-06	400	135	11	M2140
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BMP2K ARID4A WDR7 GPATCH8 WDR43 RIF1 IGF2R SACS NMT2 WBP4 MACF1 TNKS PLCB4 MPHOSPH9 NIPBL MED13	8.96e-06	856	135	16	M4500
Coexpression	BONOME_OVARIAN_CANCER_SURVIVAL_SUBOPTIMAL_DEBULKING	SELENOP SYNE1 TWNK HMGA1 KAT2B SNCAIP NMT2 WBP4 TNKS LIMCH1 SEC63 AKAP7	1.27e-05	506	135	12	M253
Coexpression	IKEDA_MIR30_TARGETS_UP	PTBP3 ARID4B ARID4A WDR7 CAST PLCB4	3.11e-05	116	135	6	M2379
Coexpression	IKEDA_MIR30_TARGETS_UP	PTBP3 ARID4B ARID4A WDR7 CAST PLCB4	3.27e-05	117	135	6	MM931
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2A	AKAP6 SELENOP PDE1C CAST NCKAP5 SMOC1 DNAH7 KAT2B SNCAIP SCG3 MKX LIMCH1	6.65e-05	600	135	12	M39055
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	SELENOP ACAA1 ACACB WDR7 BSDC1 AHCYL2 MLXIP RRBP1 KAT2B ARID1B PTCD1 ZNF75A LIMCH1 SEC63	7.50e-05	807	135	14	M16651
Coexpression	GSE41867_NAIVE_VS_DAY15_LCMV_ARMSTRONG_EFFECTOR_CD8_TCELL_DN	ZCCHC9 BSDC1 TBC1D9 ITPKC PHF20L1 MED13 AKAP7	7.98e-05	199	135	7	M9501
Coexpression	GSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_DN	SELENOP ARID4B RPLP2 ZC3H8 ARID1B CCDC66 NIPBL	7.98e-05	199	135	7	M9253
Coexpression	GSE21670_IL6_VS_TGFB_AND_IL6_TREATED_STAT3_KO_CD4_TCELL_DN	SELENOP KIF26B CGAS BSDC1 ARID1B IGF2R ZNF579	7.98e-05	199	135	7	M7451
Coexpression	GSE32423_MEMORY_VS_NAIVE_CD8_TCELL_DN	ANKRD13D SELENOP ARID4A ZCCHC8 DNAJC6 SMARCC2 PLCB4	8.23e-05	200	135	7	M5073
Coexpression	GAUTAM_EYE_IRIS_CILIARY_BODY_CILIARY_BODY_ENDOTHELIAL_CELLS	ANKRD13D PTBP3 RPLP2 TWNK SRPRB ZNF800 SAFB CCDC86 MED13	9.90e-05	356	135	9	M43609
CoexpressionAtlas	dev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000	RPLP2 ARID4A JADE3 ZC3H8 GPATCH8 SMOC1 ATAD2 TDRD1 ZC3H6 WDR43 RIF1 KAT2B ZDHHC23 NMT2 MKX MGA NOP2 TDRD12	3.89e-06	810	135	18	gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	ARID4A DYNC2H1 ZDBF2 RIF1 ZNF800 SAFB MPHOSPH9 POLQ NIPBL	3.93e-06	192	135	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	ARID4A DYNC2H1 NCKAP5 ZDBF2 RIF1 ZNF800 OTX1 SAFB SCG3 MPHOSPH9 POLQ NIPBL JHY	1.80e-05	498	135	13	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#3	ARID4B ARID4A KIF26B SYNE1 RIF1 CCDC66 SNCAIP SMARCC2 MACF1 ZNF579 MGA NIPBL	2.09e-05	432	135	12	Facebase_RNAseq_e10.5_Maxillary Arch_1000_K3
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_1000	PDE1C KALRN KIF26B AKNA CENPS ZDBF2 MEOX1 SNCAIP PRPF19 HDGFL2	3.08e-05	311	135	10	gudmap_developingKidney_e13.5_podocyte cells_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	ZDBF2 ATAD2 RIF1 ZNF800 OTX1 SAFB PHF20L1 SCG3 NMT2 MPHOSPH9 POLQ NIPBL JHY	3.58e-05	532	135	13	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_500	ZC3H8 CENPS ATAD2 RIF1 ZDHHC23 NMT2 TDRD12	5.40e-05	152	135	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_k2_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	ARID4B TCOF1 ARID4A DYNC2H1 NCKAP5 ZDBF2 AHCYL2 RIF1 ZNF800 OTX1 SAFB CCDC66 SCG3 MPHOSPH9 ZNF579 POLQ NIPBL JHY	5.61e-05	989	135	18	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_1000	ARID4B MARCHF10 ACACB TCOF1 ARID4A JADE3 KIF26B SYNE1 RIF1 CCDC66 SNCAIP SMARCC2 MACF1 LIMCH1 ZNF579 MGA NIPBL JHY	5.61e-05	989	135	18	Facebase_RNAseq_e10.5_Maxillary Arch_1000
CoexpressionAtlas	DevelopingGonad_e14.5_ ovary_emap-6699_top-relative-expression-ranked_500	JADE3 NEXMIF AHCYL2 PNMA8B RIF1 ZNF800 SACS NMT2 MGA TDRD12	1.69e-04	382	135	10	gudmap_developingGonad_e14.5_ ovary_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	ARID4B ARID4A RIF1 SAFB CCDC66 MPHOSPH9 ZNF579 POLQ NIPBL	1.72e-04	311	135	9	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ARID4B ANKRD36C ARID1B IGF2R KMT2A MACF1 ANKRD36 NIPBL MED13	6.79e-09	188	136	9	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARID4B SYNE1 ZDBF2 ANKRD36C SNCAIP KMT2A MACF1 ANKRD36	1.71e-07	197	136	8	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP6 MARCHF10 DYNC2H1 SYNE1 DNAH2 USP43 DNAH7 ADGB	1.71e-07	197	136	8	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PDE1C NCKAP5 SMOC1 DGKI PLCL1 PHLDB2 AKAP7	7.71e-07	165	136	7	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PDE1C NCKAP5 SMOC1 DGKI PLCL1 PHLDB2 AKAP7	8.70e-07	168	136	7	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-TRGV2_gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AKNA ATAD2 MPHOSPH9 PLCL1 MGA KLRC2 KLRC3	9.05e-07	169	136	7	8caf7996796a2e2716e3855de855c903d6126bf2
ToppCell	NS-moderate-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE1C NCKAP5 SMOC1 DGKI LIMCH1 PLCL1 PHLDB2	1.14e-06	175	136	7	a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	KIF26B CARMIL1 GPATCH8 ARID1B PLCB4 MPHOSPH9 MED13	1.72e-06	186	136	7	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	KIF26B CARMIL1 GPATCH8 ARID1B PLCB4 MPHOSPH9 MED13	1.72e-06	186	136	7	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	WDR7 ANKRD36C TGOLN2 ZDHHC23 MCM9 MACF1 POLQ	2.05e-06	191	136	7	9454f642c3621370fa23640b631301346b300950
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	AKAP6 MARCHF10 DYNC2H1 SYNE1 DNAH2 DNAH7 ADGB	2.27e-06	194	136	7	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 RIF1 SCG3 KMT2A MACF1 MGA PHLDB2	2.35e-06	195	136	7	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYNC2H1 RIF1 SCG3 KMT2A MACF1 MGA PHLDB2	2.35e-06	195	136	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	normal-na-Lymphocytic_NK-NK_bright-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	KIF26B SYNE1 HOXA10 GARIN4 KLRC2 KLRC3	1.14e-05	164	136	6	b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE1C NCKAP5 SMOC1 DGKI PLCL1 AKAP7	1.22e-05	166	136	6	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DYNC2H1 DNAH2 USP43 TDRD1 DNAH7 ADGB	1.35e-05	169	136	6	14aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	AKAP6 KALRN SACS PLCB4 PLD5 PLCL1	1.54e-05	173	136	6	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	Epithelial-Epithelial-C_(AT2)\|Epithelial / shred on cell class and cell subclass (v4)	SELENOP RPLP2 NEXMIF GSAP RRBP1 AKAP7	1.54e-05	173	136	6	f57cbf5bd2a9e5db47b4919e9cd5e50781c1a990
ToppCell	5'-Adult-LymphNode-Hematopoietic-T_cells-gdT\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GPATCH8 DNAJC6 SMARCC2 KLRC2 KLRC3 TDRD12	1.59e-05	174	136	6	ccc79febfcf588d8294ffc712338be96de8a5033
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARID4B SYNE1 CGAS ZNF800 TNKS PLCB4	1.81e-05	178	136	6	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	AKAP6 PDE1C NEXMIF TBC1D9 SCG3 PLCB4	1.87e-05	179	136	6	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	NS-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SELENOP PDE1C MARCHF10 NCKAP5 SMOC1 DGKI	1.87e-05	179	136	6	65a96bee7bc28f5bfc20f0fd92bcc0ab2eb5e06c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MARCHF10 DYNC2H1 DNAH2 USP43 DNAH7 ADGB	1.93e-05	180	136	6	92fb01b91261b3103454924cde56add337b41844
ToppCell	NS-critical-d_07-13-Epithelial-Ionocyte\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE1C NCKAP5 SMOC1 DGKI PLCL1 AKAP7	2.12e-05	183	136	6	ba43bca2b45be1008eebd3f033cecb061fb3a966
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	RAB11FIP2 WDR43 MCM9 MACF1 SEC63 POLQ	2.25e-05	185	136	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	NS-moderate-d_16-33-Epithelial-Ciliated\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 MARCHF10 DYNC2H1 DNAH2 DNAH7 ADGB	2.25e-05	185	136	6	5e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	RAB11FIP2 ANKRD36C MCM9 MACF1 SEC63 POLQ	2.32e-05	186	136	6	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	COVID-19-kidney-CD-IC-B\|kidney / Disease (COVID-19 only), tissue and cell type	PTBP3 PDE1C CARMIL1 SACS DGKI PLCL1	2.39e-05	187	136	6	ce05b89860573fe0356102e2998d1ef6d1968034
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 PDE1C AHCYL2 TBC1D9 DGKI LIMCH1	2.46e-05	188	136	6	58ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SELENOP NCKAP5 SMOC1 KAT2B KLRC2 KLRC3	2.46e-05	188	136	6	d9692b6048d9b85524a07a1807bdd4757731c151
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 DYNC2H1 KIF26B RAB11FIP2 TBC1D9 LIMCH1	2.54e-05	189	136	6	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	AKAP6 KALRN CARMIL1 MACF1 PLCB4 PLD5	2.54e-05	189	136	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PDE1C NCKAP5 SMOC1 DGKI PLCL1 AKAP7	2.61e-05	190	136	6	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SP4 SYNE1 AKNA MACF1 ANKRD36 KLRC3	2.61e-05	190	136	6	d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 DYNC2H1 KIF26B RAB11FIP2 TBC1D9 LIMCH1	2.61e-05	190	136	6	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	AKAP6 PDE1C ACACB NCKAP5 LIMCH1 PLCL1	2.61e-05	190	136	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE1C NCKAP5 SMOC1 DGKI PLCL1 AKAP7	2.69e-05	191	136	6	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID4B RRBP1 ARID1B TNKS NIPBL MED13	2.77e-05	192	136	6	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ARID4B ANKRD36C KMT2A MACF1 ANKRD36 PLCL1	2.77e-05	192	136	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	AKAP6 MARCHF10 DYNC2H1 DNAH2 DNAH7 ADGB	2.85e-05	193	136	6	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	AKAP6 DYNC2H1 SYNE1 DNAH2 DNAH7 ADGB	2.85e-05	193	136	6	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	severe-low-quality_cells\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 AKNA ANKRD36C SNCAIP MACF1 ANKRD36	2.85e-05	193	136	6	9337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	PDE1C KIF26B RCN2 SMOC1 SNCAIP PLCB4	2.85e-05	193	136	6	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 AKNA MACF1 ANKRD36 KLRC2 KLRC3	2.85e-05	193	136	6	fce4f805e53669acb4c188f87ac7d84408c0c218
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	PDE1C KIF26B RCN2 SMOC1 SNCAIP PLCB4	2.85e-05	193	136	6	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 AKNA MACF1 ANKRD36 KLRC2 KLRC3	2.85e-05	193	136	6	6e1498153a7766c03fddbda1701dbf1596d21736
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 AKNA GSAP GPATCH8 IGF2R KLRC3	2.85e-05	193	136	6	e790ab76c12f74a13936c231076f1e397283efb3
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID4B RRBP1 ARID1B TNKS NIPBL MED13	2.85e-05	193	136	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_neuro-secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	PDE1C JADE3 SMOC1 OTX1 SCG3 DGKI	2.94e-05	194	136	6	d024cd75a97f048257e49cee9190fb2e79202ee2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 AKNA IGF2R MACF1 KLRC2 KLRC3	2.94e-05	194	136	6	24837a27b0041fe8c348225fa8b09b127d743603
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BMP2K TCOF1 RCN2 GSAP TBC1D9 ZDHHC23	2.94e-05	194	136	6	d852aebf7a763b9a776c4570711f0c759f591910
ToppCell	3'_v3-bone_marrow-Lymphocytic_NK-NK_CD16\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 AKNA GSAP GPATCH8 IGF2R KLRC3	2.94e-05	194	136	6	7773501e076d470158dbc1d7f10c67152b326eb7
ToppCell	proximal-Hematologic-Natural_Killer_T-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	AKNA BRD3 ZDBF2 ANKRD36 KLRC2 KLRC3	3.02e-05	195	136	6	4d7c2c4d0130c2d46877ff6dd4584525d8f74daf
ToppCell	proximal-3-Hematologic-Natural_Killer_T\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	AKNA BRD3 ZDBF2 ANKRD36 KLRC2 KLRC3	3.02e-05	195	136	6	93093545bb23d2619ace029a52cffa1f673a0c2a
ToppCell	proximal-Hematologic-Natural_Killer_T\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	AKNA BRD3 ZDBF2 ANKRD36 KLRC2 KLRC3	3.02e-05	195	136	6	3944e4800f5d904d4efa401ce8913ec0e0781211
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MARCHF10 DYNC2H1 SYNE1 DNAH2 DNAH7 ADGB	3.02e-05	195	136	6	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	NS-control-d_0-4-Epithelial-Ciliated\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MARCHF10 DYNC2H1 SYNE1 DNAH2 DNAH7 ADGB	3.11e-05	196	136	6	d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SELENOP DYNC2H1 SYNE1 RRBP1 MACF1 LIMCH1	3.20e-05	197	136	6	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	AKAP6 PDE1C KALRN SACS MKX PLCB4	3.20e-05	197	136	6	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 AKNA GSAP GPATCH8 KLRC2 KLRC3	3.20e-05	197	136	6	550cce374332c49893bcf4ce4b7dceb7f5fe26aa
ToppCell	PCW_10-12\|World / Celltypes from embryonic and fetal-stage human lung	SELENOP ARID4B MACF1 LIMCH1 NIPBL TDRD12	3.20e-05	197	136	6	47fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	RPLP2 ANKRD36C NMT2 KMT2A ANKRD36 PLCL1	3.20e-05	197	136	6	836dd8110d5689f944ad1d301def38c32278b5b5
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	ANKRD13D RPLP2 ARID4A ANKRD36C RRBP1 ANKRD36	3.20e-05	197	136	6	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	healthy_donor-Lymphocytic-ILC-NK_cell\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNE1 AKNA GSAP IGF2R MACF1 KLRC2	3.29e-05	198	136	6	d7053a898e04478c577381085f615edaad3cdc5b
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-T_lymphocytic-type_I_NK_T_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SYNE1 GSAP GPATCH8 ANKRD36C MACF1 KLRC2	3.29e-05	198	136	6	58d805e827299292750b09c6283fdbe406b75f79
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	MARCHF10 DYNC2H1 SYNE1 DNAH2 DNAH7 ADGB	3.29e-05	198	136	6	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	healthy_donor-Lymphocytic-ILC\|healthy_donor / Disease condition, Lineage, Cell class and subclass	SYNE1 AKNA GSAP IGF2R MACF1 KLRC2	3.29e-05	198	136	6	aa33be29e26f1b8facfc894413099083ae3bbb1b
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-natural_killer_cell\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SYNE1 AKNA GSAP GPATCH8 KLRC2 KLRC3	3.29e-05	198	136	6	5607e36f393cb399fcc2504502498453fd32d96b
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE1 AKNA ANKRD36C ARID1B MACF1 ANKRD36	3.39e-05	199	136	6	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	COVID_non-vent-Lymphocytic-ILC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 AKNA GSAP IGF2R MACF1 KLRC2	3.39e-05	199	136	6	df4f7d5be099e3e6054f3b812ccf70251664e4c0
ToppCell	COVID_non-vent-Lymphocytic-ILC-NK_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SYNE1 AKNA GSAP IGF2R MACF1 KLRC2	3.39e-05	199	136	6	ed35d747f11f6ea6a5cb7061057f0a98d9e0db99
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SELENOP DYNC2H1 KIF26B SYNE1 MACF1 LIMCH1	3.48e-05	200	136	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	Macroglial-Astrocytes-SLC14A1---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACACB BMP2K SYNE1 CARMIL1 AHCYL2 DNAH7	3.48e-05	200	136	6	d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCell	Macroglial-Astrocytes-SLC14A1----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACACB BMP2K SYNE1 CARMIL1 AHCYL2 DNAH7	3.48e-05	200	136	6	f861509b54185d89931db64da1b9d81986cc7938
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal\|5w / Sample Type, Dataset, Time_group, and Cell type.	SELENOP RPLP2 NACA SMOC1 SRPRB TMEM38B	3.48e-05	200	136	6	fc73565f973c70915e7415f30d7295a63e33d712
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARID4B CAST ARID1B KMT2A MACF1 NIPBL	3.48e-05	200	136	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	Macroglial-Astrocytes-SLC14A1\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACACB BMP2K SYNE1 CARMIL1 AHCYL2 DNAH7	3.48e-05	200	136	6	16f468217427921fa18c6d078ffa990eb019b257
ToppCell	Macroglial-Astrocytes-SLC14A1--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACACB BMP2K SYNE1 CARMIL1 AHCYL2 DNAH7	3.48e-05	200	136	6	0442894c39eec69850c090957a5dc7bcecd21e04
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	ARID4B TGOLN2 ARID1B KMT2A MACF1 NIPBL	3.48e-05	200	136	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Macroglial-Astrocytes-SLC14A1-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	ACACB BMP2K SYNE1 CARMIL1 AHCYL2 DNAH7	3.48e-05	200	136	6	01819446deeab9054f5cfe889d53bb49d137dbc0
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	SYNE1 AKNA ANKRD36C MACF1 ANKRD36	3.52e-05	121	136	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SYNE1 ANKRD36C DGKI MACF1 ANKRD36	5.93e-05	135	136	5	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	AKNA ANKRD36C ARID1B MACF1 ANKRD36	8.87e-05	147	136	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 DNAH7 IGF2R MACF1 KLRC2	1.01e-04	151	136	5	0cc2f4aec3dae4603fa831f22c40f897e68b34e2
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	SYNE1 DNAH7 IGF2R MACF1 KLRC2	1.01e-04	151	136	5	b545823113a3450c5f841f7de48bf0937593544f
ToppCell	Ionocyte\|World / shred by cell class for nasal brushing	PDE1C MARCHF10 SMOC1 DGKI PLCL1	1.10e-04	154	136	5	6b78fb0c96fc7b5e901c39b3424f4aa8d0a6b9cf
ToppCell	normal-na-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	TDRD1 ARHGEF33 ANKRD36 MPHOSPH9 KLRC2	1.14e-04	155	136	5	08295584395e8d9cfc1b1648f98754b3ac53e587
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PDE1C CENPS ZDHHC23 SCG3 KLRC2	1.17e-04	156	136	5	33deda19f06172079ef1dd49fd54d66da1e7fb14
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PTBP3 PDE1C MARCHF10 USP43 DGKI	1.25e-04	158	136	5	debebc8534a80e5500051f6fd352dc201585968d
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C MARCHF10 NEXMIF DGKI AKAP7	1.32e-04	160	136	5	9049707a4487f2337a17976ceb5fbd8815ab9e1d
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory-Ionocyte-Ionocyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C MARCHF10 NEXMIF DGKI AKAP7	1.32e-04	160	136	5	f2cfec54cf48a655f473b830be7d141c54b521ff
ToppCell	cellseq2-Epithelial-Epithelial_Neuro-Secretory\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	PDE1C MARCHF10 NEXMIF DGKI AKAP7	1.32e-04	160	136	5	0eb50b3c494e1b65d40104b3b5411b57bb72b959
ToppCell	normal_Lung-Myeloid_cells-Undetermined\|Myeloid_cells / Location, Cell class and cell subclass	SELENOP RPLP2 ZDBF2 DNAH7 ARHGEF33	1.36e-04	161	136	5	283012858e575c70d09950de53da041509f59bfa
ToppCell	Basal_cells-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	NEXMIF USP43 ZNF300 GARIN4 OTX1	1.48e-04	164	136	5	b15a26130a1ea1b370b6e3be21f02a0d6aaf6b3c
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-Activated_CD8_T\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MARCHF10 AKNA MPHOSPH9 MGA KLRC2	1.48e-04	164	136	5	24fdea5113d92b96f56b06dd2449910a3c785e69
ToppCell	Ionocyte\|World / shred by cell class for turbinate	PDE1C KIF26B DGKI PLCL1 AKAP7	1.53e-04	165	136	5	0cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCell	wk_20-22-Hematologic-Myeloid-GMP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ANKRD13D ACACB HMGA1 ARID1B MPHOSPH9	1.57e-04	166	136	5	d96e88e73a40205f32cebd7e54ca1ff09ee1e7e8
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CARMIL1 NCKAP5 TMEM38B IGF2R ZNF579	1.61e-04	167	136	5	a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCell	wk_20-22-Hematologic-Myeloid-CMP\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HMGA1 TDRD1 TMEM38B HOXA10 CCDC86	1.66e-04	168	136	5	e223bd7ae2a28c007e8b365f30d50d3bee83ba38
ToppCell	NS-critical-d_16-33-Epithelial-Ionocyte\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	PDE1C NCKAP5 SMOC1 DGKI PLCL1	1.66e-04	168	136	5	6a233045638cb83dab64789b996b7598c325001e
Drug	Famotidine [76824-35-6]; Down 200; 11.8uM; HL60; HG-U133A	ZCCHC8 NACA BRD3 DPF2 GPALPP1 ITPKC MPHOSPH9 NIPBL MED13	3.13e-06	200	135	9	2029_DN
Drug	Disulfides	ACAA1 SYNE1 RCN2 KMT2A	1.15e-05	24	135	4	CID000089871
Drug	Betamethasone [378-44-9]; Down 200; 10.2uM; MCF7; HT_HG-U133A	GAK JADE3 RRBP1 DNAJC6 RIF1 NMT2 WBP4 NIPBL	2.12e-05	194	135	8	5328_DN
Drug	Piroxicam [36322-90-4]; Down 200; 12uM; PC3; HT_HG-U133A	BMP2K AHCYL2 PTBP1 RUSC2 HOXA10 ITPKC SAFB NOP2	2.28e-05	196	135	8	2089_DN
Drug	Deoxycorticosterone [64-85-7]; Down 200; 12.2uM; HL60; HT_HG-U133A	PTBP3 AHCYL2 TRAFD1 KMT2A TNKS PLCB4 NIPBL AKAP7	2.36e-05	197	135	8	3099_DN
Drug	Sulfameter [651-06-9]; Down 200; 14.2uM; MCF7; HT_HG-U133A	PTBP3 CARMIL1 RAB11FIP2 BSDC1 IGF2R KMT2A SMARCC2 NIPBL	2.36e-05	197	135	8	6212_DN
Drug	Biotin [58-85-5]; Down 200; 16.4uM; HL60; HT_HG-U133A	BMP2K SYNE1 RUSC2 GPALPP1 HOXA10 NMT2 MACF1 PLCB4	2.45e-05	198	135	8	2428_DN
Drug	Norethynodrel [68-23-5]; Down 200; 13.4uM; PC3; HT_HG-U133A	BMP2K JADE3 NACA DPF2 TBC1D9 RUSC2 GPALPP1 WBP4	2.45e-05	198	135	8	1818_DN
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; PC3; HG-U133A	ZCCHC8 DNAJC6 HOXA10 WBP4 KMT2A LIMCH1 MPHOSPH9 NIPBL	2.54e-05	199	135	8	1960_DN
Drug	phosphorus pentasulfide	ACAA1 SYNE1	3.49e-05	2	135	2	CID000014817
Disease	aspartate aminotransferase measurement	SP4 KALRN ZC3H8 CARMIL1 CAST DNAH2 AKNA BRD3 HMGA1 PTBP1 RRBP1 TRAFD1 WBP4 TNKS KLRC2 KLRC3	3.02e-06	904	132	16	EFO_0004736
Disease	mean corpuscular hemoglobin concentration	BMP2K KALRN ARID4A CARMIL1 CTDSP1 BRD3 SMOC1 MYLK2 RIF1 ZNF800 KAT2B MACF1 DOT1L HDGFL2 KLRC2 MED13 AKAP7	9.26e-06	1105	132	17	EFO_0004528
Disease	Parkinson's disease 19A (implicated_via_orthology)	GAK DNAJC6	1.99e-05	2	132	2	DOID:0060891 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	DPF2 ARID1B SMARCC2	2.42e-05	13	132	3	C0265338
Disease	platelet crit	SP4 ARID4B KALRN CARMIL1 RCN2 HMGA1 GPATCH8 RRBP1 MYLK2 TRAFD1 MPHOSPH9 DOT1L HDGFL2 KLRC2	9.69e-05	952	132	14	EFO_0007985
Disease	schizophrenia, intelligence, self reported educational attainment	AKAP6 PDE1C CARMIL1 BRD3 KMT2A DGKI MPHOSPH9 PLCL1	1.72e-04	346	132	8	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	muscular disease (implicated_via_orthology)	ACACB NMT2	1.97e-04	5	132	2	DOID:0080000 (implicated_via_orthology)
Disease	cognitive function measurement, self reported educational attainment	AKAP6 SP4 PDE1C CARMIL1 ZNF800 ARID1B SCG3 PLCL1	2.05e-04	355	132	8	EFO_0004784, EFO_0008354
Disease	apolipoprotein A 1 measurement	ACACB AKNA ZC3H11B BRD3 HMGA1 MLXIP RRBP1 TGOLN2 ZNF483 KMT2A MACF1 MGA	4.39e-04	848	132	12	EFO_0004614
Disease	serum alanine aminotransferase measurement	ZCCHC8 DNAH2 AKNA ZC3H11B BRD3 MLXIP PTBP1 TRAFD1 WBP4 MCM9 TNKS KLRC2	5.45e-04	869	132	12	EFO_0004735
Disease	response to statin, low density lipoprotein cholesterol measurement	DZIP1 LIMCH1	5.46e-04	8	132	2	EFO_0004611, GO_0036273
Disease	Cornelia De Lange Syndrome	KMT2A NIPBL	5.46e-04	8	132	2	C0270972
Disease	Intellectual Disability	AKAP6 ZCCHC8 SYNE1 DPF2 SACS SMARCC2 MACF1 MED13	9.35e-04	447	132	8	C3714756
Disease	Umbilical hernia	ZC3H11B PLCL1	1.06e-03	11	132	2	HP_0001537
Disease	acute myeloid leukemia (implicated_via_orthology)	ARID4A KMT2A	1.27e-03	12	132	2	DOID:9119 (implicated_via_orthology)
Disease	body weight	AKAP6 PTBP3 PDE1C NEXMIF CAST BSDC1 HMGA1 SMOC1 MKX PLCL1 DOT1L MGA NIPBL AKAP7	1.58e-03	1261	132	14	EFO_0004338
Disease	body fat percentage	PDE1C ZCCHC8 CAST ZC3H11B BRD3 PHF20L1 MACF1 TNKS	1.63e-03	488	132	8	EFO_0007800
Disease	Drug habituation	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0013170
Disease	Substance-Related Disorders	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0236969
Disease	Drug abuse	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0013146
Disease	Drug Use Disorders	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0013222
Disease	Drug Dependence	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C1510472
Disease	Substance Dependence	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0038580
Disease	Substance Use Disorders	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0038586
Disease	Organic Mental Disorders, Substance-Induced	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C0029231
Disease	Prescription Drug Abuse	PDE1C SYNE1 LIMCH1 AKAP7	1.80e-03	115	132	4	C4316881
Disease	Substance abuse problem	PDE1C SYNE1 LIMCH1 AKAP7	1.86e-03	116	132	4	C0740858
Disease	red blood cell density measurement	SP4 BMP2K KALRN RAB11FIP2 DNAH2 ZC3H11B CTDSP1 KAT2B ARID1B PHF20L1 KLRC2	2.05e-03	880	132	11	EFO_0007978
Disease	Insulin Sensitivity	SELENOP ACACB HMGA1	2.49e-03	60	132	3	C0920563
Disease	Insulin Resistance	SELENOP ACACB HMGA1	2.49e-03	60	132	3	C0021655
Disease	attention deficit hyperactivity disorder, schizophrenia	DGKI MPHOSPH9 PLCL1	2.99e-03	64	132	3	EFO_0003888, MONDO_0005090
Disease	C-reactive protein measurement	AKAP6 CARMIL1 CAST BRD3 CCDC168 PTBP1 DNAJC6 PTCD1 SCG3 SMARCC2 MACF1 TNKS AKAP7	2.99e-03	1206	132	13	EFO_0004458
Disease	response to methotrexate, neurotoxicity	MACF1 PLCL1	3.23e-03	19	132	2	EFO_0011057, GO_0031427
Disease	Malignant neoplasm of breast	AKAP6 KALRN RPLP2 DYNC2H1 SYNE1 RIF1 ARID1B WBP4 SLC39A6 ZNF75A MACF1 NIPBL	3.25e-03	1074	132	12	C0006142
Disease	osteoarthritis	KIF26B ZC3H11B MPHOSPH9 DOT1L TDRD12	3.29e-03	222	132	5	MONDO_0005178
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	ACACB ZC3H11B IGF2R MACF1 TNKS	3.42e-03	224	132	5	EFO_0004530, EFO_0008317
Disease	age at voice drop	ZNF483 JHY	4.33e-03	22	132	2	EFO_0007888

Protein segments in the cluster

Peptide	Gene	Start	Entry
IKSPSKDASSGKENR	PRPF4B	326	Q13523
GLKPSGQDSKKENAD	TDRD1	446	Q9BXT4
QKRVKDAQGGGSSSK	ARID4B	1116	Q4LE39
DAQGGGSSSKKQKRS	ARID4B	1121	Q4LE39
ARTQSPGKCGKNGDK	ARID4B	1186	Q4LE39
AGRQLKKGGKQASAS	BRD3	546	Q15059
KKSEDGSKNSRQPAE	CENPS	116	Q8N2Z9
GSSSQAPASKKLNKE	CCDC86	216	Q9H6F5
PKRTSAAAKNEKNGT	ARID4A	1091	P29374
DQDKSRSKAGKTPFQ	ANKRD13D	286	Q6ZTN6
NSDSGKSTPSNNGKK	BSDC1	371	Q9NW68
VKEPNSKNSAGSESK	ADGB	1446	Q8N7X0
NKNKPGEGSSVKTEA	AKAP7	321	Q9P0M2
QNKNKPGEGSSVKTE	AKAP7	76	O43687
KATFQGSDGKRNSKE	ARHGEF33	291	A8MVX0
SSAGRKKEQEGKGDS	ARID1B	1921	Q8NFD5
KDGEKSGTVSSQKQP	ANKRD36	741	A6QL64
QKKPAATTAKAGDGS	ATAD2	46	Q6PL18
QRGKEGSDANPFLSK	DOT1L	1356	Q8TEK3
NGKTSPASKDQRTGK	BMP2K	711	Q9NSY1
KSGSRQKKSAPDTQE	CGAS	56	Q8N884
KRFEKANQDSGPGLS	RCN2	156	Q14257
SKLKSPSQKQDGGTA	RBM15	761	Q96T37
KKQDTEAARKQPGTG	ITPKC	251	Q96DU7
SDNQENRGKPEGSSK	MEOX1	156	P50221
GQQAGSPSKEDKKQA	ACACB	141	O00763
KDGEKSGTVSSQKQP	ANKRD36C	741	Q5JPF3
KDGEKSGTVSPQKQS	ANKRD36C	1081	Q5JPF3
ALGDKQRKANESKGT	ELOA2	406	Q8IYF1
GKGEQKESPQSAASL	JHY	176	Q6NUN7
KEKPNSGGTKSDSAS	NMT2	56	O60551
IQPKQEKKGGRSSAD	MGA	2281	Q8IWI9
KASSGLEANPGEKRK	KAT2B	416	Q92831
EGEGGRKNSSNFKKA	HDAC1	426	Q13547
DDKKEKGCGNPGSSR	GARIN4	471	Q8IYT1
SKPSSLGVSNGAEKK	KIF26B	266	Q2KJY2
GTKPDEKSSDQGLQK	GPATCH8	331	Q9UKJ3
SNKGESAANRKGPSK	MKX	286	Q8IYA7
TSVKKPKAEQGASGS	MYLK2	106	Q9H1R3
ANKSDNPRGKNSKAE	PDE1C	581	Q14123
NPRGKNSKAEKSSGE	PDE1C	586	Q14123
GKGDQKSAASQKPRS	CTDSP1	21	Q9GZU7
TTPQGDSADEKSKKG	KALRN	1811	O60229
KQGDSNKSRSDKLGF	NIPBL	896	Q6KC79
DGGSRSKQGNEQSKK	MPHOSPH9	161	Q99550
ASTGAKTNRADPKKS	MACF1	3421	O94854
KASPEKDSLGNSKGE	HOXA10	311	P31260
KPSSGKKGATTQNSE	TWNK	651	Q96RR1
ALGGNSSPSAKDIKK	RPLP2	11	P05387
SDKSSDNSGLKRKTP	HDGFL2	146	Q7Z4V5
TGAKTNRADPKKSAS	MACF1	7296	Q9UPN3
QQQSGSGTKSRPAKK	OTX1	96	P32242
PSDTNKILTGGADKN	PRPF19	231	Q9UMS4
SGKSDPKNVAALKNR	MLXIP	706	Q9HAP2
NQGFSSRSDKKGPKT	GAK	1186	O14976
KGSFDPKNAKRASTA	DYNC2H1	3071	Q8NCM8
STKEGKRNELQPGSK	GSAP	111	A4D1B5
SKGKTPQERAQQAGD	DGKI	1026	O75912
PGASQNEGKTSDKKV	POLQ	1001	O75417
QGNKKKQLPTGDSSA	DNAH7	341	Q8WXX0
KSTQKSDKGRDDPGQ	GPALPP1	121	Q8IXQ4
RGKGSSNLEGKQKAA	DNAJC6	766	O75061
KPVGSETSQAKGEKN	CCDC66	71	A2RUB6
KSKTTKDSPQAARDG	AKNA	1186	Q7Z591
SSSKAPKNGGKAKDS	CAST	681	P20810
TEKDRGGSENAKKSP	MARCHF10	386	Q8NA82
KSSQIPKRNGKENGT	KMT2A	2736	Q03164
KNTKAEPKAEAGSRS	CARMIL1	1231	Q5VZK9
QKSSETGKKANGVPS	CCDC168	4306	Q8NDH2
ELSKAINGDGKTSPN	DNAH2	846	Q9P225
AKSGQSKKPSDELSQ	SACS	1796	Q9NZJ4
SIGNGKSQPNSKFAK	JADE3	651	Q92613
KSQPNSKFAKSNGLE	JADE3	656	Q92613
NSQEDKNDGGKSRKG	LIMCH1	636	Q9UPQ0
SKSSQPLASKQEKDG	HMGA1	6	P17096
KTGSKPRTSANSNKD	PHF20L1	186	A8MW92
SQGKEKSEPGQRSKV	MCM9	781	Q9NXL9
DKNGSKNLGKFISSP	IGF2R	541	P11717
FPRGSSNSSSEKKKG	RUSC2	1291	Q8N2Y8
SEPENNNKKPKTSGS	SP4	26	Q02446
DSSSTAPAQLGKKGK	SRPRB	216	Q9Y5M8
KPAFKKDGSTTAGNS	ACAA1	261	P09110
SPRDKQQKNSKGSSD	AHCYL2	171	Q96HN2
PSDTSKNDKKGKANT	PLCB4	866	Q15147
NKTATDDTGGKDPRN	PLD5	521	Q8N7P1
RTAKAKPSKQQGAGD	TRAFD1	561	O14545
QDKLPGSSAEKASKA	SYNE1	5231	Q8NF91
GTVEGGDQSNPKSKK	TCOF1	1426	Q13428
DTKSADNPDGGLQSK	NCKAP5	1571	O14513
QRKPKGNKSSISGTE	KLRC2	21	P26717
AGKAEQTGNKRSKPL	RIF1	1291	Q5UIP0
EQGSPAEQGDKKAKS	TDRD12	776	Q587J7
PKRESKSGALKQSSD	NEXMIF	346	Q5QGS0
AGTPQESKKKINSGS	NEXMIF	1371	Q5QGS0
GSAQDDAAGSRKKKG	PNMA8B	581	Q9ULN7
TDAKGNPASSASKGK	SNCAIP	901	Q9Y6H5
QRKPKGNKSSISGTE	KLRC3	21	Q07444
PGSKKSANGSDDKAS	MED13	796	Q9UHV7
SENSSQPAKKAKGAA	NOP2	616	P46087
NSLGNSKRTKLGEKD	PHLDB2	276	Q86SQ0
VNSPDSDRRDKKGGN	SMARCC2	281	Q8TAQ2
PQNKGSFGKNTVKSD	DZIP1	706	Q86YF9
TEASASURUKNQAKK	SELENOP	361	P49908
NERPSAGSKANKEFG	SRP68	41	Q9UHB9
GSGEKSKDQDDQKPG	SAFB	531	Q15424
SDSSGKDPRNSQGKG	SLC39A6	151	Q13433
GSGKQAKNTKSSAVP	AKAP6	516	Q13023
PNKSGAEAKTQKDSS	TGOLN2	81	O43493
KSGADGQTPKDGSSK	TGOLN2	181	O43493
GAEKQTPKDGSNKSG	TGOLN2	211	O43493
DPSNQKCGGRKKTVS	PLCL1	81	Q15111
PLSQGNSGRKDDGSK	SMOC1	166	Q9H4F8
SDGPNTARKLKENAG	USP43	906	Q70EL4
GSPKKQKNESNSAGS	ZCCHC8	426	Q6NZY4
SSGENSKNQKKSGGL	ZC3H6	1066	P61129
KEKKQRGAGSNAGAS	ZXDC	726	Q2QGD7
KTEGAQGKKAERSPN	RRBP1	521	Q9P2E9
NTSEKVNKTSGPKRG	SSX5	146	O60225
PGKANTSEKINKRSG	SSX8P	141	Q7RTT4
KHGADPTKKNRDGNT	TNKS	771	O95271
SLKPDKGKRANSQEN	TBC1D9	986	Q6ZT07
FKEKNKNSDGGSDPE	WBP4	251	O75554
KNSDGGSDPETQKEK	WBP4	256	O75554
KKSEAKSPSNGVGSL	TMEM38B	256	Q9NVV0
KDPRNAGLKGKSCQS	ZDBF2	1691	Q9HCK1
SQRSEEQKSKKGPDG	DPF2	251	Q92785
PAEDGQGETNKNRTK	SEC63	496	Q9UGP8
KKDSRRSDKLNNGGS	RAB11FIP2	366	Q7L804
TPSTANGNDSKKFKR	PTBP3	36	O95758
SGKNDDKGNKGSSKR	TPH2	41	Q8IWU9
GSLNNRTTKDDPKGS	ZDHHC23	231	Q8IYP9
ASKGQSEEPAGKTKS	ZC3H11B	451	A0A1B0GTU1
GFTSKGLSPKENNKE	ZNF677	61	Q86XU0
KRGDASKPLSDAQGK	ZNF830	176	Q96NB3
KGSFEGTSQNLPKRK	ZCCHC9	26	Q8N567
EKTAGEKSRKSNDGG	ZNF483	351	Q8TF39
KANASNSPEGNKTKG	ZNF800	641	Q2TB10
GKSPTGLKLKNDTEN	ZNF75A	66	Q96N20
KFRTKPQGDQDTGKE	PTCD1	676	O75127
AAGKKDDKASGARNS	ZNF579	331	Q8NAF0
GNDSKKFKGDSRSAG	PTBP1	41	P26599
SPENLQKASGSSDKG	WDR7	716	Q9Y4E6
GSLKDSTKDDNSNPG	SCG3	381	Q8WXD2
SNSRKKPDQSFGGGK	ZNF300	206	Q96RE9
ASEKTKGATSPGQKA	WDR43	581	Q15061
RNSGSQEEDGKPKEK	ZC3H8	161	Q8N5P1
SAKQPVTKNNKGSGT	NACA	1876	E9PAV3
AESGKSEKGQPQNSK	NDUFV3	36	P56181