Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	aspartic-type endopeptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25	5.20e-08	37	111	6	GO:0004190
GeneOntologyMolecularFunction	aspartic-type peptidase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25	6.15e-08	38	111	6	GO:0070001
GeneOntologyMolecularFunction	RNA-DNA hybrid ribonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	2.90e-07	11	111	4	GO:0004523
GeneOntologyMolecularFunction	RNA-directed DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	8.67e-07	14	111	4	GO:0003964
GeneOntologyMolecularFunction	RNA stem-loop binding	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.03e-06	21	111	4	GO:0035613
GeneOntologyMolecularFunction	RNA endonuclease activity, producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.19e-05	37	111	4	GO:0016891
GeneOntologyMolecularFunction	DNA polymerase activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.77e-05	38	111	4	GO:0034061
GeneOntologyMolecularFunction	peptidase activity	RCE1 ERVK-6 USP34 USP45 ERVK-7 ERVK-10 USP8 GZMH USP32 ERVK-8 ERVK-18 SCPEP1 ERVK-25	7.00e-05	654	111	13	GO:0008233
GeneOntologyMolecularFunction	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	ERVK-6 ERVK-7 ERVK-10 ERVK-8	1.23e-04	46	111	4	GO:0016893
GeneOntologyMolecularFunction	endopeptidase activity	RCE1 ERVK-6 USP34 ERVK-7 ERVK-10 USP8 GZMH ERVK-8 ERVK-18 ERVK-25	1.44e-04	430	111	10	GO:0004175
GeneOntologyMolecularFunction	nucleotidyltransferase activity	ERVK-6 TUT4 ERVK-7 ERVK-10 POLR3B ERVK-8	2.07e-04	152	111	6	GO:0016779
GeneOntologyMolecularFunction	RNA endonuclease activity	ERVK-6 ERVK-7 ERVK-10 ERVK-8	9.86e-04	79	111	4	GO:0004521
GeneOntologyMolecularFunction	hexosyltransferase activity	EXT2 GCNT1 GALNT7 PIGV GALNT5 POFUT2	1.17e-03	211	111	6	GO:0016758
GeneOntologyMolecularFunction	protein tyrosine kinase binding	DOCK4 RASGRF1 TRIM6 GAB4 PITPNM3	1.47e-03	149	111	5	GO:1990782
GeneOntologyMolecularFunction	receptor tyrosine kinase binding	DOCK4 RASGRF1 GAB4 PITPNM3	1.60e-03	90	111	4	GO:0030971
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2B1 ATP2B3	1.63e-03	11	111	2	GO:0005388
GeneOntologyBiologicalProcess	DNA integration	ERVK-6 ERVK-7 ERVK-10 ERVK-8	5.28e-07	13	110	4	GO:0015074
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B3	1.83e-04	4	104	2	IPR022141
Domain	ATP_Ca_trans_C	ATP2B1 ATP2B3	1.83e-04	4	104	2	PF12424
Domain	P-type_ATPase_IIB	ATP2B1 ATP2B3	1.83e-04	4	104	2	IPR006408
Domain	USP_CS	USP34 USP45 USP8 USP32	5.02e-04	66	104	4	IPR018200
Domain	RASGEF_CAT	RASGRF1 RAPGEF2 RAPGEFL1	5.52e-04	29	104	3	PS50009
Domain	RasGEF	RASGRF1 RAPGEF2 RAPGEFL1	6.10e-04	30	104	3	PF00617
Domain	-	RASGRF1 RAPGEF2 RAPGEFL1	6.10e-04	30	104	3	1.10.840.10
Domain	RASGEF_cat_dom	RASGRF1 RAPGEF2 RAPGEFL1	6.10e-04	30	104	3	IPR001895
Domain	RasGEF	RASGRF1 RAPGEF2 RAPGEFL1	6.10e-04	30	104	3	SM00147
Domain	Ras_GEF_dom	RASGRF1 RAPGEF2 RAPGEFL1	6.10e-04	30	104	3	IPR023578
Domain	USP_1	USP34 USP45 USP8 USP32	6.27e-04	70	104	4	PS00972
Domain	UCH	USP34 USP45 USP8 USP32	6.62e-04	71	104	4	PF00443
Domain	USP_2	USP34 USP45 USP8 USP32	6.62e-04	71	104	4	PS00973
Domain	USP_3	USP34 USP45 USP8 USP32	6.98e-04	72	104	4	PS50235
Domain	USP_dom	USP34 USP45 USP8 USP32	6.98e-04	72	104	4	IPR028889
Domain	Peptidase_C19_UCH	USP34 USP45 USP8 USP32	6.98e-04	72	104	4	IPR001394
Domain	PyrdxlP-dep_Trfase_major_sub2	PDXDC1 SPTLC2 AADAT	1.05e-03	36	104	3	IPR015422
Pubmed	Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.	ERVK-6 ERVK-7 ERVK-10	1.33e-07	4	113	3	10469592
Pubmed	Quantitation of HERV-K env gene expression and splicing in human breast cancer.	ERVK-6 ERVK-7 ERVK-18	3.32e-07	5	113	3	12629516
Pubmed	A revised nomenclature for transcribed human endogenous retroviral loci.	ERVK-6 ERVK-7 ERVK-10 ERVK-8 ERVK-18 ERVK-25	6.64e-07	94	113	6	21542922
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 SMCHD1 LMTK2 NFASC ICE1 SLC7A6 ADGRA2 GRAMD4 TAOK2 FAM53B DAGLA	1.31e-06	529	113	11	14621295
Pubmed	Genetic deletion or small-molecule inhibition of the arginine methyltransferase PRMT5 exhibit anti-tumoral activity in mouse models of MLL-rearranged AML.	PRMT5 KMT2A	1.05e-05	2	113	2	28663579
Pubmed	The involvement of L-type amino acid transporters in theanine transport.	SLC7A6 SLC7A5	1.05e-05	2	113	2	23221699
Pubmed	Cloning and characterization of mouse UBPy, a deubiquitinating enzyme that interacts with the ras guanine nucleotide exchange factor CDC25(Mm)/Ras-GRF1.	RASGRF1 USP8	1.05e-05	2	113	2	11500497
Pubmed	Interferon-alpha-induced endogenous superantigen. a model linking environment and autoimmunity.	ERVK-6 ERVK-18	1.05e-05	2	113	2	11672541
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	DOCK4 USP34 NFASC SPATA2 GRAMD4	2.05e-05	101	113	5	9872452
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	DOCK4 HJURP LMTK2 USP8 RADIL PRMT5 KMT2A FAM53B MAPK4 RAPGEF2 ATP2B1 CDK3	2.46e-05	861	113	12	36931259
Pubmed	Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.	ERVK-10 ERVK-18 ERVK-25	2.63e-05	18	113	3	18664271
Pubmed	Distribution and evolution of von Willebrand/integrin A domains: widely dispersed domains with roles in cell adhesion and elsewhere.	VIT HMCN2	3.13e-05	3	113	2	12388743
Pubmed	Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.	ERVK-6 ERVK-18	3.13e-05	3	113	2	10516026
Pubmed	Defective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1.	PECAM1 RAPGEF2	3.13e-05	3	113	2	17826737
Pubmed	RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis.	PECAM1 RAPGEF2	3.13e-05	3	113	2	20595512
Pubmed	Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm.	TICRR ZNF695	3.13e-05	3	113	2	36311753
Pubmed	Biological variation in the sizes, shapes and locations of visual cortical areas in the mouse.	CUX2 RORB	3.13e-05	3	113	2	31042712
Pubmed	A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis.	DOCK4 PECAM1	3.13e-05	3	113	2	26129894
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	RCE1 USP34 SPTLC2 EXT2 GCNT1 GALNT7 PRMT5 DHCR7 SLC22A3 PGAP1 SLC7A5 SCPEP1 ATP2B1 POFUT2	3.62e-05	1201	113	14	35696571
Pubmed	Pharyngeal mesoderm regulatory network controls cardiac and head muscle morphogenesis.	MSC TCF21 PECAM1	5.64e-05	23	113	3	23112163
Pubmed	Inhibitory interaction of the 14-3-3 proteins with ubiquitous (PMCA1) and tissue-specific (PMCA3) isoforms of the plasma membrane Ca2+ pump.	ATP2B1 ATP2B3	6.25e-05	4	113	2	18029012
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B1 ATP2B3	6.25e-05	4	113	2	12209837
Pubmed	Definitive hematopoiesis requires the mixed-lineage leukemia gene.	PECAM1 KMT2A	6.25e-05	4	113	2	15030765
Pubmed	Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression.	SLC7A6 SLC7A5	6.25e-05	4	113	2	22007000
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B1 ATP2B3	6.25e-05	4	113	2	12784250
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B1 ATP2B3	6.25e-05	4	113	2	15101689
Pubmed	Amino acid transport of y+L-type by heterodimers of 4F2hc/CD98 and members of the glycoprotein-associated amino acid transporter family.	SLC7A6 SLC7A5	6.25e-05	4	113	2	9878049
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B1 ATP2B3	6.25e-05	4	113	2	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B3	6.25e-05	4	113	2	8245032
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B1 ATP2B3	6.25e-05	4	113	2	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B1 ATP2B3	6.25e-05	4	113	2	8634322
Pubmed	Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.	ABCA1 DHCR7	6.25e-05	4	113	2	18775956
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B1 ATP2B3	6.25e-05	4	113	2	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B1 ATP2B3	6.25e-05	4	113	2	11152753
Pubmed	VIP interneurons in mouse primary visual cortex selectively enhance responses to weak but specific stimuli.	CUX2 RORB	6.25e-05	4	113	2	33108272
Pubmed	Ornithine transport via cationic amino acid transporter-1 is involved in ornithine cytotoxicity in retinal pigment epithelial cells.	SLC7A6 SLC7A5	6.25e-05	4	113	2	17197568
Pubmed	Association of 4F2hc with light chains LAT1, LAT2 or y+LAT2 requires different domains.	SLC7A6 SLC7A5	6.25e-05	4	113	2	11311135
Pubmed	Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.	ERVK-6 ERVK-10	6.25e-05	4	113	2	7983737
Pubmed	A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses.	EXT2 GALNT5	6.25e-05	4	113	2	10545594
Pubmed	Identification and characterization of a membrane protein (y+L amino acid transporter-1) that associates with 4F2hc to encode the amino acid transport activity y+L. A candidate gene for lysinuric protein intolerance.	SLC7A6 SLC7A5	6.25e-05	4	113	2	9829974
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B1 ATP2B3	6.25e-05	4	113	2	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B1 ATP2B3	6.25e-05	4	113	2	10434059
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	USP34 CUX2 NFASC ADGRA2 DIP2C DAGLA	9.74e-05	225	113	6	12168954
Pubmed	Control of facial muscle development by MyoR and capsulin.	MSC TCF21	1.04e-04	5	113	2	12493912
Pubmed	Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.	ERVK-6 ERVK-7	1.04e-04	5	113	2	11401426
Pubmed	Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.	ATP2B1 ATP2B3	1.04e-04	5	113	2	17938178
Pubmed	Impaired vascular development in the yolk sac and allantois in mice lacking RA-GEF-1.	PECAM1 RAPGEF2	1.04e-04	5	113	2	19635461
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP34 USP45 SMARCAL1 USP8 USP32	1.23e-04	147	113	5	29576527
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP34 USP45 USP8 USP32	1.45e-04	81	113	4	12838346
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	RCE1 TICRR DNAH2 NFASC PCARE ICE1 FAM186B PRMT5 GZMH PITPNM3	1.49e-04	736	113	10	29676528
Pubmed	GOLPH3 and GOLPH3L are broad-spectrum COPI adaptors for sorting into intra-Golgi transport vesicles.	COPB1 GCNT1 GALNT7	1.55e-04	32	113	3	34473204
Pubmed	A large-scale standardized physiological survey reveals functional organization of the mouse visual cortex.	CUX2 RORB	1.56e-04	6	113	2	31844315
Pubmed	Musculin and TCF21 coordinate the maintenance of myogenic regulatory factor expression levels during mouse craniofacial development.	MSC TCF21	1.56e-04	6	113	2	22318627
Pubmed	Docking protein Gab1 is an essential component of postnatal angiogenesis after ischemia via HGF/c-met signaling.	PECAM1 GAB4	1.56e-04	6	113	2	21293003
Pubmed	Analysis of recently identified prostate cancer susceptibility loci in a population-based study: associations with family history and clinical features.	LMTK2 SLC22A3	1.56e-04	6	113	2	19366831
Pubmed	1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.	SPTLC2 PECAM1	1.56e-04	6	113	2	34762852
Pubmed	The conditional inactivation of the beta-catenin gene in endothelial cells causes a defective vascular pattern and increased vascular fragility.	PECAM1 CTNNA2	1.56e-04	6	113	2	12975353
Pubmed	Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.	ATP2B1 ATP2B3	1.56e-04	6	113	2	12767889
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RASGRF1 RSL1D1 SMCHD1 ICE1 SYCP2 HMCN2 RBM15B	1.84e-04	361	113	7	26167880
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	USP34 TICRR USP45 RSL1D1 HJURP LMTK2 FAM171B GALNT7 NPHP3 PGAP1 FBXO7 ATP2B1	2.17e-04	1084	113	12	11544199
Pubmed	Association of 17 prostate cancer susceptibility loci with prostate cancer risk in Chinese men.	LMTK2 SLC22A3	2.17e-04	7	113	2	19866473
Pubmed	Aberrant Cortical Activity in Multiple GCaMP6-Expressing Transgenic Mouse Lines.	CUX2 RORB	2.17e-04	7	113	2	28932809
Pubmed	Loss of MLL Induces Epigenetic Dysregulation of Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis.	RASGRF1 KMT2A	2.17e-04	7	113	2	36098964
Pubmed	Identification of guanine nucleotide exchange factors (GEFs) for the Rap1 GTPase. Regulation of MR-GEF by M-Ras-GTP interaction.	RAPGEF2 RAPGEFL1	2.17e-04	7	113	2	10934204
Pubmed	Platelet-derived growth factor receptor beta signaling is required for efficient epicardial cell migration and development of two distinct coronary vascular smooth muscle cell populations.	TCF21 PECAM1	2.17e-04	7	113	2	18948621
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	PDXDC1 USP34 COPB1 RSL1D1 BEND3 FAM171B SPATA2 DHCR7 SLC7A5 RAPGEF2	2.29e-04	777	113	10	35844135
Pubmed	Association of prostate cancer risk variants with clinicopathologic characteristics of the disease.	LMTK2 SLC22A3	2.89e-04	8	113	2	18794092
Pubmed	Gene knockout studies of Ca2+-transporting ATPases.	ATP2B1 ATP2B3	2.89e-04	8	113	2	10951186
Pubmed	Individual and cumulative association of prostate cancer susceptibility variants with clinicopathologic characteristics of the disease.	LMTK2 SLC22A3	2.89e-04	8	113	2	20450899
Pubmed	IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons.	CUX2 RORB	2.89e-04	8	113	2	21104742
Pubmed	Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development.	GALNT7 GALNT5	2.89e-04	8	113	2	11159923
Pubmed	Established prostate cancer susceptibility variants are not associated with disease outcome.	LMTK2 SLC22A3	2.89e-04	8	113	2	19423541
Pubmed	Prognostic significance of prostate cancer susceptibility variants on prostate-specific antigen recurrence after radical prostatectomy.	LMTK2 SLC22A3	2.89e-04	8	113	2	19900942
Pubmed	Pod1 is required in stromal cells for glomerulogenesis.	TCF21 PECAM1	2.89e-04	8	113	2	12619136
Pubmed	Fbxw8 is essential for Cul1-Cul7 complex formation and for placental development.	PECAM1 CUL7	2.89e-04	8	113	2	16880526
Pubmed	The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.	SMCHD1 NCKAP5 RADIL PRMT5 RBM15B KMT2A	3.23e-04	281	113	6	24163370
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	USP34 COPB1 RSL1D1 SPTLC2 SPEG SMCHD1 PRMT5 CTNNA2 MAPK4 ATP2B1 DAGLA	3.31e-04	971	113	11	33306668
Pubmed	Generalizability of associations from prostate cancer genome-wide association studies in multiple populations.	LMTK2 SLC22A3	3.71e-04	9	113	2	19318432
Pubmed	Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch.	MSC TCF21	3.71e-04	9	113	2	17384148
Pubmed	Metabolic activation-related CD147-CD98 complex.	SLC7A6 SLC7A5	3.71e-04	9	113	2	15901826
Pubmed	Interaction of TAGLN and USP1 promotes ZEB1 ubiquitination degradation in UV-induced skin photoaging.	USP34 USP32	3.71e-04	9	113	2	37149635
Pubmed	Ulk4, a Newly Discovered Susceptibility Gene for Schizophrenia, Regulates Corticogenesis in Mice.	CUX2 RORB	3.71e-04	9	113	2	34235142
Pubmed	Genomic analysis of mouse retinal development.	CDHR1 MYO1H HJURP GRAMD4 TAOK2 PPP2R5A PRMT5 PITPNM3 KMT2A FAM53B RORB	4.46e-04	1006	113	11	15226823
Pubmed	Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.	PECAM1 ADGRA2	4.63e-04	10	113	2	21071672
Pubmed	Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation.	PECAM1 ADGRA2	4.63e-04	10	113	2	28803732
Pubmed	Developmental and cell-specific expression of thyroid hormone transporters in the mouse cochlea.	PECAM1 SLC7A5	4.63e-04	10	113	2	21878515
Pubmed	Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas.	CUX2 RORB	4.63e-04	10	113	2	26705332
Pubmed	Angiogenic sprouting into neural tissue requires Gpr124, an orphan G protein-coupled receptor.	PECAM1 ADGRA2	4.63e-04	10	113	2	21282641
Pubmed	Glycine receptors control the generation of projection neurons in the developing cerebral cortex.	CUX2 RORB	4.63e-04	10	113	2	24926615
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	SMCHD1 KMT2A SLC7A5 ATP2B1 ATP2B3	5.31e-04	202	113	5	24639526
Pubmed	Prostate cancer risk associated loci in African Americans.	LMTK2 SLC22A3	5.65e-04	11	113	2	19549807
Pubmed	Disrupted gonadogenesis and male-to-female sex reversal in Pod1 knockout mice.	TCF21 PECAM1	5.65e-04	11	113	2	15289436
Pubmed	Lis1 is essential for cortical microtubule organization and desmosome stability in the epidermis.	DSC1 CTNNA2	5.65e-04	11	113	2	21844209
Pubmed	Multiple newly identified loci associated with prostate cancer susceptibility.	LMTK2 SLC22A3	5.65e-04	11	113	2	18264097
Pubmed	Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.	CUL7 PRMT5	5.65e-04	11	113	2	31570706
Pubmed	Replication of prostate cancer risk loci on 8q24, 11q13, 17q12, 19q33, and Xp11 in African Americans.	LMTK2 SLC22A3	5.65e-04	11	113	2	19902474
Pubmed	Differential patterning of genes involved in serotonin metabolism and transport in extra-embryonic tissues of the mouse.	PECAM1 SLC22A3	5.65e-04	11	113	2	27238716
Pubmed	Inherited genetic markers discovered to date are able to identify a significant number of men at considerably elevated risk for prostate cancer.	LMTK2 SLC22A3	5.65e-04	11	113	2	20878950
Pubmed	Common polymorphisms influencing serum uric acid levels contribute to susceptibility to gout, but not to coronary artery disease.	SLC17A2 SLC22A11	5.65e-04	11	113	2	19890391
Pubmed	Genome-wide association study in Han Chinese identifies four new susceptibility loci for coronary artery disease.	TCF21 ATP2B1	5.65e-04	11	113	2	22751097
GeneFamily	Ubiquitin specific peptidases	USP34 USP45 USP8 USP32	7.26e-05	56	72	4	366
GeneFamily	ATPases Ca2+ transporting	ATP2B1 ATP2B3	5.53e-04	9	72	2	1209
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_k-means-cluster#3_top-relative-expression-ranked_100	ENPP3 PECAM1	6.97e-05	3	103	2	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_k3_100
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#3_top-relative-expression-ranked_100	ENPP3 PECAM1	6.97e-05	3	103	2	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k3_100
CoexpressionAtlas	dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_100	ENPP3 PECAM1	6.97e-05	3	103	2	gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k1_100
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_100	ENPP3 PECAM1	6.97e-05	3	103	2	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k2_100
CoexpressionAtlas	dev gonad_e11.5_F_PrimGermCell_Oct_k-means-cluster#2_top-relative-expression-ranked_200	ENPP3 PECAM1	6.97e-05	3	103	2	gudmap_dev gonad_e11.5_F_PrimGermCell_Oct_k2_200
CoexpressionAtlas	dev gonad_e11.5_M_PrimGermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_200	ENPP3 PECAM1	6.97e-05	3	103	2	gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_k1_200
CoexpressionAtlas	dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_100	ENPP3 PECAM1	1.39e-04	4	103	2	gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k4_100
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_NK-Cycling_NK\|lymph-node_spleen / Manually curated celltypes from each tissue	TICRR ZNF695 C21orf58 HJURP SH2D1B HASPIN	6.65e-06	190	107	6	451eaceb0cb0ec6cfcae00253c0e5c92a168c2f3
ToppCell	AT1_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	ABCA1 NCKAP5 RTKN2 RADIL GALNT5 MAPK4	7.06e-06	192	107	6	0444f9e9cef7403e220e862b5a787443d3f5c9ac
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP34 TUT4 PECAM1 NCKAP5 TAOK2 KMT2A	8.91e-06	200	107	6	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TUT4 SPTLC2 PECAM1 NCKAP5 TAOK2 PPP2R5A	8.91e-06	200	107	6	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CDHR1 GPX2 GCNT1 SLC22A3 PADI1	2.02e-05	137	107	5	5cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCell	severe_COVID-19-NK_CD56bright\|World / disease group, cell group and cell class (v2)	C21orf58 CDHR1 IL18RAP RADIL PITPNM3	3.32e-05	152	107	5	ab5a4e47b23d16018642d4c9c7f41b30205edf73
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MISP3 RTKN2 HMCN2 PITPNM3 FAM53B	4.50e-05	162	107	5	34b4cd3d2258f88dfbd6d32abd1db87aff8a6b6f
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MISP3 RTKN2 HMCN2 PITPNM3 FAM53B	4.63e-05	163	107	5	56b8668dbf06faa6866ec71f29b92907b73f074d
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	C21orf58 CDHR1 HJURP SH2D1B GZMH	4.63e-05	163	107	5	466c8129852a5b16cd9fcc6b79e799abc21bb21a
ToppCell	normal-na-Lymphocytic_NK-NK_bright-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	CDHR1 MYO1H IL18RAP FAM186B SH2D1B	4.77e-05	164	107	5	b5a91f2cbfad9a2bc38aea576085a37865df955d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CIDEB TICRR C21orf58 RTKN2 AADAT	4.91e-05	165	107	5	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|390C / Donor, Lineage, Cell class and subclass (all cells)	TICRR C21orf58 MYO1H HJURP HMCN2	5.65e-05	170	107	5	5319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF1 SOX8 SLC7A5 SCPEP1 PADI1	5.65e-05	170	107	5	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF1 SOX8 SLC7A5 SCPEP1 PADI1	5.65e-05	170	107	5	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 PECAM1 NCKAP5 GCNT1 SPATA2	5.98e-05	172	107	5	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDHR1 PECAM1 NCKAP5 GCNT1 SPATA2	5.98e-05	172	107	5	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TICRR PIGV SYCP2 SH2D1B HASPIN	5.98e-05	172	107	5	fe3d0d8cb5f613ac2cfff450599698f1533a354f
ToppCell	10x5'-GI_small-bowel-Lymphocytic_NK\|GI_small-bowel / Manually curated celltypes from each tissue	CDHR1 VIT RADIL SH2D1B GZMH	6.31e-05	174	107	5	09b216f07cffd3ea2149ea95ffb5cd7219b3a98c
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC17A2 BCL2L10 MISP3 RTKN2 PITPNM3	6.49e-05	175	107	5	442f261a3b2c4d2523f7d4089178f8c79cac2f0f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	GCNT1 IL18RAP TAOK2 SH2D1B GZMH	6.49e-05	175	107	5	63e977b8bafae1c5f742fc35a4cc712fefa9727f
ToppCell	PND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SLC17A2 BCL2L10 MISP3 RTKN2 PITPNM3	6.49e-05	175	107	5	35fb7735dd3355476fe60404833cb60bd066bcf1
ToppCell	pdx-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC17A2 ABCA1 CUX2 TUT4 SLC22A3	6.66e-05	176	107	5	1e21f80cf0e695ffdd63e4a72cf1e3fa41b60341
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIDEB SPEG C15orf39 ACOT1 PADI1	7.03e-05	178	107	5	de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C21orf58 DNAH2 NFASC WDR97 DLEC1	7.03e-05	178	107	5	3b12db04006db6e94fc45649a4b3a63b92f21a61
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	C21orf58 DNAH2 ECT2L WDR97 DLEC1	7.22e-05	179	107	5	5e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR C21orf58 HJURP RTKN2 HASPIN	7.22e-05	179	107	5	88d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 SMCHD1 USP8 PGAP1 ATP2B1	7.81e-05	182	107	5	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	LMTK2 NCKAP5 RTKN2 GALNT5 MAPK4	8.01e-05	183	107	5	6821dca076318115d360ff426eb1218cfe104063
ToppCell	CV-Severe-3\|CV / Virus stimulation, Condition and Cluster	C15orf39 GCNT1 GZMH HASPIN SLC7A5	8.22e-05	184	107	5	1c9bda00bb6efd98f68781ca06655bf6c4282f27
ToppCell	wk_08-11-Epithelial-PNS-COL20A1+_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SLC22A11 SOX8 ARPC1B RORB ITIH6	8.43e-05	185	107	5	abec2a49fe0f0fa4cba49347207a1ee317333657
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR C21orf58 HJURP NFASC ADGRA2	8.87e-05	187	107	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR C21orf58 HJURP NFASC ADGRA2	8.87e-05	187	107	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 NCKAP5 RTKN2 GALNT5 MAPK4	9.09e-05	188	107	5	e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-CD56_bright_NK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	HJURP IL18RAP SYCP2 SH2D1B GZMH	9.09e-05	188	107	5	0a2be6eac6fde669fbc58fd1b2e93e4acf17ddde
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	NCKAP5 RTKN2 RADIL DIP2C GALNT5	9.32e-05	189	107	5	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK4 LMTK2 NCKAP5 RTKN2 MAPK4	9.56e-05	190	107	5	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	facs-MAT\|facs / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MSC TCF21 ENPP3 VIT SCPEP1	9.80e-05	191	107	5	b4fba92f9bd1354a07fedfca7304a3757e6d5beb
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Myeloid\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RCE1 MSC C21orf58 C15orf39 SPATA2	1.08e-04	195	107	5	027075e9c62b5754a014a9d1393e1b0f5ae42e41
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Myeloid-Megakaryocyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	RCE1 MSC C21orf58 C15orf39 SPATA2	1.08e-04	195	107	5	1bcc0c8b1281396b1433ce5a2ec8681de47ce9ad
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR C21orf58 HJURP RTKN2 HASPIN	1.08e-04	195	107	5	75759fd7f925725f0ecd07214afcca5aa2158f9e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	USP34 TUT4 SMCHD1 GZMH KMT2A	1.08e-04	195	107	5	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	severe-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	USP34 ENPP3 SMCHD1 RTKN2 KMT2A	1.13e-04	197	107	5	57ebd552f10d6278623b52a3d484d4b91ae1d028
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SMARCAL1 NFASC SOX8 WDR97 PGAP1	1.13e-04	197	107	5	31c8d6e565bbdc37843ce871fe91845b0cc18a9f
ToppCell	3'-Broncho-tracheal-Immune_Myeloid\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA1 ARPC1B THAP2 SLC7A5 ATP2B1	1.13e-04	197	107	5	d568354aff89ac84dd06360f19100ef578a041ed
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SMCHD1 HJURP WDR97 SH2D1B GZMH	1.13e-04	197	107	5	52246d1354c4e2b13d48c878643edf843d2b50d2
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Dividing_Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TICRR C21orf58 HJURP RTKN2 PADI1	1.16e-04	198	107	5	f088badb90c6c2d916195f5649eda102119c9ac6
ToppCell	ASK428-Epithelial-Type_1\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	DOCK4 ABCA1 NCKAP5 RTKN2 GALNT5	1.16e-04	198	107	5	0047a9ef7684230ac5179efea94461480e90bdaf
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MSC TCF21 NFASC ADGRA2 SLC22A3	1.19e-04	199	107	5	0cdbedf09ec72734b86ddab3fec562e066afed92
ToppCell	5'-Adult-SmallIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RSL1D1 CDHR1 GPX2 GCNT1 PGAP1	1.19e-04	199	107	5	f544229f471b4717166dd4b588399afe45cc31b5
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TICRR C21orf58 HJURP NCKAP5 RTKN2	1.19e-04	199	107	5	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	Influenza-Influenza_Severe-Others-RBC\|Influenza_Severe / Disease, condition lineage and cell class	C21orf58 HJURP FBXO7 SLC7A5 RAPGEF2	1.19e-04	199	107	5	da0fec0a492bc3827d9066d2590bcd466cd45564
ToppCell	distal-2-Epithelial-Alveolar_Epithelial_Type_1\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ABCA1 NCKAP5 RTKN2 GALNT5 MAPK4	1.22e-04	200	107	5	313ec1e53bd738a9cb48dc5b946261156f99f44b
ToppCell	Sepsis-ICU-NoSEP-Lymphocyte-T/NK-gd_T\|ICU-NoSEP / Disease, condition lineage and cell class	ECT2L FAM171B DHCR7 GZMH PITPNM3	1.22e-04	200	107	5	2c2cea7691c340912f6ad77667a580a071eaeb8b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TUT4 PECAM1 NCKAP5 TAOK2 PPP2R5A	1.22e-04	200	107	5	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	Bronchus_Control_(B.)-Immune-TX-MoAM-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	ABCA1 PECAM1 THAP2 SLC7A5 ATP2B1	1.22e-04	200	107	5	fe7f8b04067b6680b69c8523f0fa514ef97207e2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TICRR C21orf58 HJURP RTKN2 HASPIN	1.22e-04	200	107	5	0bba93f1271dac704dddcdea8cb0f84a7ac6f42a
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Stem_cells-Neuroepithelial_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TICRR C21orf58 HJURP RTKN2 HASPIN	1.22e-04	200	107	5	c9479452ab8c51139522383f745f02171ebbd7e2
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B1 ATP2B3	1.90e-04	6	106	2	DOID:0050429 (implicated_via_orthology)
Disease	premature menopause (biomarker_via_orthology)	CIDEB ABCA1	3.53e-04	8	106	2	DOID:10787 (biomarker_via_orthology)
Disease	neuroimaging measurement, brain volume measurement	PDXDC1 USP34 BEND3 NCKAP5 FAM171B FAM53B	5.97e-04	286	106	6	EFO_0004346, EFO_0006930
Disease	metabolic syndrome	PDXDC1 ABCA1 CUX2 TAOK2 KMT2A	7.92e-04	200	106	5	EFO_0000195
Disease	level of Phosphatidylinositol (18:0_20:3) in blood serum	PDXDC1 DAGLA	8.24e-04	12	106	2	OBA_2045157
Disease	omega-3 polyunsaturated fatty acid measurement	PDXDC1 ABCA1 SLC22A3 DAGLA	8.82e-04	118	106	4	EFO_0010119
Disease	fatty acid measurement	PDXDC1 ABCA1 MYO1H SLC22A3 KMT2A CTNNA2 DAGLA	1.02e-03	436	106	7	EFO_0005110
Disease	1-stearoyl-2-dihomo-linolenoyl-GPI (18:0/20:3n3 or 6) measurement	PDXDC1 DAGLA	1.13e-03	14	106	2	EFO_0022085
Disease	vitamin D measurement	ABCA1 CUX2 COPB1 ENPP3 DHCR7 PADI1	1.37e-03	336	106	6	EFO_0004631
Disease	free cholesterol in HDL measurement	PDXDC1 ABCA1 MYO1H	1.39e-03	61	106	3	EFO_0022264
Disease	uric acid measurement	USP34 ABCA1 CUX2 SLC22A11 LMTK2 SLC22A3 DIP2C FAM53B	1.63e-03	610	106	8	EFO_0004761
Disease	Coronary Arteriosclerosis	TCF21 PECAM1 ATP2B1	1.67e-03	65	106	3	C0010054
Disease	Coronary Artery Disease	TCF21 PECAM1 ATP2B1	1.67e-03	65	106	3	C1956346
Disease	level of Phosphatidylcholine (15:0_18:2) in blood serum	PDXDC1 DAGLA	1.88e-03	18	106	2	OBA_2045065
Disease	triglyceride measurement, body mass index	PDXDC1 SLC22A3	2.10e-03	19	106	2	EFO_0004340, EFO_0004530
Disease	metabolite measurement, diet measurement	PDXDC1 SLC22A3 DAGLA	2.16e-03	71	106	3	EFO_0004725, EFO_0008111
Disease	phospholipids in large HDL measurement	PDXDC1 ABCA1 MYO1H	2.33e-03	73	106	3	EFO_0022190
Disease	total lipids in large HDL	PDXDC1 ABCA1 MYO1H	2.43e-03	74	106	3	EFO_0022189
Disease	level of Phosphatidylcholine (18:1_20:4) in blood serum	ABCA1 DAGLA	2.57e-03	21	106	2	OBA_2045104
Disease	Disproportionate short stature	SMARCAL1 EXT2 CUL7	2.72e-03	77	106	3	C0878659
Disease	progression free survival, ovarian serous carcinoma	VIT CTNNA2	2.82e-03	22	106	2	EFO_0004920, EFO_1001516
Disease	free cholesterol in large HDL measurement	PDXDC1 ABCA1 MYO1H	2.92e-03	79	106	3	EFO_0022157
Disease	Renal glomerular disease	SMARCAL1 NPHP3	3.08e-03	23	106	2	C0268731
Disease	Glomerulopathy Assessment	SMARCAL1 NPHP3	3.08e-03	23	106	2	C4521256
Disease	sensory peripheral neuropathy, remission	KMT2A DLEC1	3.08e-03	23	106	2	EFO_0009785, MONDO_0002321
Disease	alcohol drinking	CUX2 ICE1 CTNNA2	3.14e-03	81	106	3	EFO_0004329
Disease	susceptibility to childhood ear infection measurement	SLC22A3 FAM53B CTNNA2 GALNT5	3.42e-03	171	106	4	EFO_0007904

Protein segments in the cluster

Peptide	Gene	Start	Entry
LWALEPEKPLVRLVK	ACOT1	81	Q86TX2
IVPDSLRDILSRWKP	AADAT	166	Q8N5Z0
PAPRTIRIEWLKSKS	CDHR1	746	Q96JP9
TLLERGPLVTARWKK	BCL2L10	106	Q9HD36
KARVLHKELTWRAPP	ADGRA2	856	Q96PE1
LKGRTWKPTLVILRI	ARPC1B	81	O15143
RKAKWTTAVRPLRLP	GZMH	116	P20718
IIWRSLPTDPQLKER	GRAMD4	391	Q6IC98
PLSRIIWKALKPLLV	ABCA1	366	O95477
LRKKELFKVRPPWVS	ECT2L	196	Q008S8
VLLPLVDRRFPKKWE	FAM186B	416	Q8IYM0
ILARPKPWRKLTVKG	CUX2	591	O14529
RLSDIWAKTPPITRK	DHCR7	81	Q9UBM7
DKIWPKLRVLARSSP	ATP2B1	756	P20020
RLDKVWPKLRVLARS	ATP2B3	751	Q16720
WPKLRVLARSSPTDK	ATP2B3	756	Q16720
TLKWLISPVKIVSRP	HJURP	406	Q8NCD3
LPKPWEERRKRRSLS	RBM15B	586	Q8NDT2
RTRVKEPIGKARWPL	PADI1	56	Q9ULC6
DSEKPLLIQELWKPR	RADIL	136	Q96JH8
RPGRRSKKIWLVPID	BEND3	521	Q5T5X7
LVKKALRVLPTVTWR	IL18RAP	526	O95256
QELLRKWTPRISPED	MTMR11	666	A4FU01
STWEVKRPLRKLLPE	MAPK4	266	P31152
LVSWRKDRVPLDPRS	HMCN2	3716	Q8NDA2
RPLGSKVWTPVEKRR	FAM53B	131	Q14153
WKSELPRDHPAVIKR	RCE1	56	Q9Y256
KPTDKLRALPLWLSL	PDXDC1	331	Q6P996
RSKILTVRVILAPWK	PECAM1	586	P16284
KLLLVFWEIVPKTTP	COPB1	76	P53618
SKEPRSRWDIVRLIP	CUL7	1531	Q14999
ILTQWDRTLKPLKTR	FMO4	486	P31512
LTTWILPKITRREPL	HERVK_113	446	P63132
IWLRHRKPELERPIK	SLC7A5	416	Q01650
KKVFPLRWTAPELVT	LMTK2	301	Q8IWU2
LTTWILPKITRREPL	ERVK-7	446	P63135
LTTWILPKITRREPL	ERVK-6	446	Q9BXR3
LTTWILPKITRREPL	ERVK-18	446	Q9QC07
RIRLQVSKSPLWPKE	NFASC	131	O94856
PKWTRKGLEEIVPNL	CDK3	241	Q00526
DKSRLRNRPVKPSIW	ICE1	1506	Q9Y2F5
RWSELLKLPIPVDKF	DOCK4	466	Q8N1I0
SPIILKWDPKSLEIR	CTNNA2	6	P26232
LPATSLRKPWKLDRQ	C21orf58	6	P58505
EERISTLLKWLDLPK	ENPP3	296	O14638
TLLKWLDLPKAERPR	ENPP3	301	O14638
RLLKRTWPLEVPETE	FBXO7	6	Q9Y3I1
WRTIPPDVIAKNRIK	GALNT5	646	Q7Z7M9
LWKRVPLTPQEKRLR	GALNT7	361	Q86SF2
LRKSPPEKKLRLFAW	GAB4	46	Q2WGN9
RTWPLILDTDDLPKK	DIP2C	1106	Q9Y2E4
LIVGKLSPWIRPDSK	PRMT5	81	O14744
LSPWIRPDSKVEKIR	PRMT5	86	O14744
RPSLTVTPKRWKLRA	HASPIN	91	Q8TF76
VTPKRWKLRARPSLT	HASPIN	96	Q8TF76
KRLLKDSPRLLPRWA	ITIH6	1276	Q6UXX5
LLDVLQRSTKPKWRI	DAGLA	541	Q9Y4D2
DTALKRSKRRWAPIP	DSC1	126	Q08554
PTLSALPWEEREKIL	KMT2A	1091	Q03164
EILTVKFKKRPRWTP	GCNT1	76	Q02742
DPKLIIWSPVRRSDV	GPX2	136	P18283
WNLTPKAKERTREPL	DLEC1	276	Q9Y238
WLEKRPKAEVEPLQR	DNAH2	2241	Q9P225
LPESARWLIIKGKPD	SLC22A11	276	Q9NSA0
WVVPESPRWLITRKK	SLC22A3	286	O75751
TNIWKKREERPLIPI	FAM171B	811	Q6P995
EVREDLAWPLKKREP	PCARE	246	A6NGG8
RQKSIKDILDPRSWL	RTKN2	591	Q8IZC4
KLLLIDWPELKESIP	SMCHD1	1256	A6NHR9
TKESPPLVVLELWQR	FER1L5	1141	A0AVI2
RKVLLEPPSVITKWG	NCKAP5	411	O14513
KTLLKTEEWVLVLPP	POFUT2	71	Q9Y2G5
PAKLLEEFPRWLEKL	NPHP3	596	Q7Z494
PIRKKLKIIPEDQSW	SCPEP1	316	Q9HB40
RKEWPLLVVVPSSVR	SMARCAL1	476	Q9NZC9
LPEKPREARAPLKSW	SPATA32	296	Q96LK8
NPSTPKREKAEWLLR	TAOK2	601	Q9UL54
LWLALKRPSELPKDI	PGAP1	711	Q75T13
LGKLWRLLSESEKRP	SOX8	136	P57073
KKPISAIPARWLRSL	RASGRF1	696	Q13972
HLLKPIKRTSPSLRW	SH2D1B	96	O14796
LTEPVIRGLLKFWPK	PPP2R5A	306	Q15172
PKKVLRELLRWTSTL	CIDEB	171	Q9UHD4
WLPSCRKEKLQPRLS	C15orf39	441	Q6ZRI6
VKPQRIWTKRDIRPD	PGBD2	106	Q6P3X8
LTTWILPKITRREPL	ERVK-25	446	P63136
PLLRSLKTVPWKPLA	PIGV	426	Q9NUD9
LAPVARLRTTWEKLP	RAPGEF2	816	Q9Y4G8
WESRKPPLKASLSLR	SPATA2	261	Q9UM82
KTTPDIIKDWPRRKR	TICRR	1676	Q7Z2Z1
KPELIICLEARKEPW	ZNF695	61	Q8IW36
SLPIIEERVSKPLLW	USP45	381	Q70EL2
KLVVIWPPRRKVSEN	MISP3	196	Q96FF7
PWVPLRKARSLEQPK	SPEG	426	Q15772
WKIPSKELRVRLTLP	RSL1D1	71	O76021
PRTRRPWKKILILVE	SPTLC2	301	O15270
LPKRWDKEPLSSLRG	WDR97	1011	A6NE52
ISWLREPKSKPQLID	SYCP2	951	Q9BX26
LWPKIRVPLKVVRTA	EXT2	501	Q93063
KWAPPLERSKLTTIA	SLC17A2	171	O00624
LTTWILPKITRREPL	ERVK-10	446	P10266
PDRAWLIEPRKVQKL	RORB	381	Q92753
LTTWILPKITRREPL	ERVK-8	446	P63133
LPRWRESFIVLESKP	VIT	126	Q6UXI7
RLKTTLPWVPPDTKL	TCF21	101	O43680
LAAPIPTVEEKWRLL	POLR3B	16	Q9NW08
PTVEEKWRLLPAFLK	POLR3B	21	Q9NW08
LSPANPREKWLRKRT	PITPNM3	611	Q9BZ71
LRWKEPKRPRPLKLS	SLC7A6	411	Q92536
PWRSTPKTDVLRLVL	TNFRSF14	11	Q92956
PLDPKRRKEWVRLVR	THAP2	26	Q9H0W7
WLKKLTLLIPETAVR	USP34	1656	Q70CQ2
AVSRLRLTWEKLPGK	RAPGEFL1	526	Q9UHV5
WPKRRIAIEDPFSVK	TUT4	666	Q5TAX3
RRDSLKKIEIWKLPP	USP8	991	P40818
TKKLDLWRLPPILII	USP32	1266	Q8NFA0
FWTLRKPEALPTKLR	TRIM6	261	Q9C030
KTVLDKSWLRPPGIL	MYO1H	796	Q8N1T3
WVPPDTKLSKLDTLR	MSC	136	O60682