Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM1 ACSM2A ACSM2B	2.91e-06	3	286	3	GO:0018858
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM1 ACSM2A ACSM2B	1.15e-05	4	286	3	GO:0102391
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	ACSM1 UBA1 SLC27A4 ATG7 ACSM2A ACSM2B	2.42e-05	41	286	6	GO:0016877
GeneOntologyMolecularFunction	ATP-dependent activity	ABCA4 VPS4A ACSM1 RAD54L2 UBA1 MDN1 RECQL4 CHD6 SLC27A4 PMS1 PMS2P1 PMS2P5 PMS2 SMARCA5 ATG7 ATAD2 ABCC6 IQCA1 SMC3 SLFN13 ACSM2A SMC1B ACSM2B	2.82e-05	614	286	23	GO:0140657
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM1 ACSM2A ACSM2B	1.54e-04	8	286	3	GO:0004321
GeneOntologyMolecularFunction	ATP-dependent DNA damage sensor activity	PMS1 PMS2P1 PMS2P5 PMS2	1.67e-04	20	286	4	GO:0140664
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	INPP4A INPP4B	2.04e-04	2	286	2	GO:0016316
GeneOntologyMolecularFunction	inositol-3,4-bisphosphate 4-phosphatase activity	INPP4A INPP4B	2.04e-04	2	286	2	GO:0052828
GeneOntologyMolecularFunction	inositol-1,3,4-trisphosphate 4-phosphatase activity	INPP4A INPP4B	2.04e-04	2	286	2	GO:0017161
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCA4 VPS4A RAD54L2 MDN1 RECQL4 CHD6 PMS1 PMS2P1 PMS2P5 PMS2 SMARCA5 ATAD2 ABCC6 IQCA1 SMC3 SLFN13 SMC1B	2.26e-04	441	286	17	GO:0016887
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B APCS	3.24e-04	10	286	3	GO:0001849
GeneOntologyMolecularFunction	DNA damage sensor activity	PMS1 PMS2P1 PMS2P5 PMS2	3.49e-04	24	286	4	GO:0140612
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	RAD54L2 RECQL4 CHD6 DNASE1L3 PMS1 PMS2P1 PMS2P5 PMS2 SMARCA5 POLE LIG4 TOP3A	4.20e-04	262	286	12	GO:0140097
GeneOntologyMolecularFunction	catalytic activity, acting on a nucleic acid	RAD54L2 SLFN14 AGO3 RECQL4 CHD6 TFB2M ELAC1 DNASE1L3 FDXACB1 PMS1 PMS2P1 PMS2P5 PMS2 SMARCA5 POLE LIG4 POLR3B SLFN13 PARN METTL8 TOP3A	4.28e-04	645	286	21	GO:0140640
GeneOntologyMolecularFunction	phosphatidylinositol-4,5-bisphosphate binding	OBSCN DAB2 SYT9 EXOC7 SYT3 SYT10 SLC9A1	4.34e-04	95	286	7	GO:0005546
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM1 ACSM2A ACSM2B	4.41e-04	11	286	3	GO:0031956
GeneOntologyMolecularFunction	fatty acid ligase activity	ACSM1 SLC27A4 ACSM2A ACSM2B	4.80e-04	26	286	4	GO:0015645
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	RAD54L2 RECQL4 CHD6 PMS1 PMS2P1 PMS2P5 PMS2 SMARCA5	4.95e-04	127	286	8	GO:0008094
GeneOntologyMolecularFunction	CoA-ligase activity	ACSM1 SLC27A4 ACSM2A ACSM2B	5.58e-04	27	286	4	GO:0016405
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM5B KDM4E KDM6A JMJD1C	6.43e-04	28	286	4	GO:0141052
GeneOntologyMolecularFunction	molecular sensor activity	PMS1 PMS2P1 PMS2P5 PMS2 MICU3	7.28e-04	50	286	5	GO:0140299
GeneOntologyMolecularFunction	glycine binding	GLDC GRIN3B GRIN2B	9.41e-04	14	286	3	GO:0016594
GeneOntologyMolecularFunction	acid-thiol ligase activity	ACSM1 SLC27A4 ACSM2A ACSM2B	9.56e-04	31	286	4	GO:0016878
GeneOntologyMolecularFunction	histone demethylase activity	KDM5B KDM4E KDM6A JMJD1C	9.56e-04	31	286	4	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM5B KDM4E KDM6A JMJD1C	1.08e-03	32	286	4	GO:0140457
GeneOntologyMolecularFunction	phosphatidylinositol-3,4-bisphosphate phosphatase activity	INPP4A INPP4B	1.20e-03	4	286	2	GO:0106017
GeneOntologyBiologicalProcess	negative regulation of receptor internalization	LRRTM1 MTMR2 ANKRD13D NECAB2 ANKRD13A	3.78e-06	18	288	5	GO:0002091
GeneOntologyCellularComponent	mismatch repair complex	PMS1 PMS2P1 PMS2P5 PMS2	1.05e-05	11	286	4	GO:0032300
Domain	A2M	C4A C4B C5 PZP	1.01e-05	10	283	4	PF00207
Domain	A2M_N_2	C4A C4B C5 PZP	1.01e-05	10	283	4	IPR011625
Domain	A2M_comp	C4A C4B C5 PZP	1.01e-05	10	283	4	IPR011626
Domain	A2M_recep	C4A C4B C5 PZP	1.01e-05	10	283	4	PF07677
Domain	A2M_comp	C4A C4B C5 PZP	1.01e-05	10	283	4	PF07678
Domain	A2M_N_2	C4A C4B C5 PZP	1.01e-05	10	283	4	PF07703
Domain	A2M_N	C4A C4B C5 PZP	1.01e-05	10	283	4	PF01835
Domain	A2M_N	C4A C4B C5 PZP	1.01e-05	10	283	4	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B C5 PZP	1.01e-05	10	283	4	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B C5 PZP	1.01e-05	10	283	4	PS00477
Domain	Macroglobln_a2	C4A C4B C5 PZP	1.01e-05	10	283	4	IPR001599
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B C5	3.37e-05	5	283	3	IPR001840
Domain	Anaphylatoxin_comp_syst	C4A C4B C5	3.37e-05	5	283	3	IPR018081
Domain	Clathrin_mu_CS	AP2M1 AP3M2 AP3M1	6.66e-05	6	283	3	IPR018240
Domain	CLAT_ADAPTOR_M_1	AP2M1 AP3M2 AP3M1	6.66e-05	6	283	3	PS00990
Domain	CLAT_ADAPTOR_M_2	AP2M1 AP3M2 AP3M1	6.66e-05	6	283	3	PS00991
Domain	AMP-binding_C	ACSM1 SLC27A4 ACSM2A ACSM2B	1.05e-04	17	283	4	PF13193
Domain	AMP-bd_C	ACSM1 SLC27A4 ACSM2A ACSM2B	1.05e-04	17	283	4	IPR025110
Domain	ANATO	C4A C4B C5	1.15e-04	7	283	3	SM00104
Domain	ANAPHYLATOXIN_2	C4A C4B C5	1.15e-04	7	283	3	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B C5	1.15e-04	7	283	3	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B C5	1.15e-04	7	283	3	IPR000020
Domain	ANATO	C4A C4B C5	1.15e-04	7	283	3	PF01821
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B C5 PZP	1.34e-04	18	283	4	IPR008930
Domain	FN3	EPHA6 OBSCN IL22RA1 USH2A SDK1 NDNF SDK2 TRIM42 FSD1 LRRN3 ROS1	2.36e-04	199	283	11	PS50853
Domain	FN3_dom	EPHA6 OBSCN IL22RA1 USH2A SDK1 NDNF SDK2 TRIM42 FSD1 LRRN3 ROS1	3.60e-04	209	283	11	IPR003961
Domain	Clathrin_mu	AP2M1 AP3M2 AP3M1	3.82e-04	10	283	3	IPR001392
Domain	JmjC	KDM5B KDM4E KDM6A JMJD1C	4.32e-04	24	283	4	PF02373
Domain	Adap_comp_sub	AP2M1 AP3M2 AP3M1	5.19e-04	11	283	3	PF00928
Domain	FN3	EPHA6 OBSCN USH2A SDK1 NDNF SDK2 TRIM42 FSD1 LRRN3 ROS1	5.37e-04	185	283	10	SM00060
Domain	AMP-binding_CS	ACSM1 SLC27A4 ACSM2A ACSM2B	5.93e-04	26	283	4	IPR020845
Domain	-	TRRAP UTP20 CAB39L ATXN10 KPNB1 TOGARAM2 HEATR1 API5 ATAD2 WDFY4 SERAC1	5.97e-04	222	283	11	1.25.10.10
Domain	NHE_CaM-bd	SLC9A1 SLC9A2	6.79e-04	3	283	2	IPR032103
Domain	NEXCaM_BD	SLC9A1 SLC9A2	6.79e-04	3	283	2	PF16644
Domain	Brdyknn_1_rcpt	BDKRB1 AGTR1	6.79e-04	3	283	2	IPR001186
Domain	Longin-like_dom	AP2M1 AP3M2 API5 AP3M1	7.93e-04	28	283	4	IPR011012
Domain	AMP_BINDING	ACSM1 SLC27A4 ACSM2A ACSM2B	7.93e-04	28	283	4	PS00455
Domain	fn3	EPHA6 OBSCN USH2A SDK1 SDK2 TRIM42 FSD1 LRRN3 ROS1	8.32e-04	162	283	9	PF00041
Domain	MHD	AP2M1 AP3M2 AP3M1	8.80e-04	13	283	3	PS51072
Domain	MHD	AP2M1 AP3M2 AP3M1	8.80e-04	13	283	3	IPR028565
Domain	ARM-like	TRRAP UTP20 CAB39L ATXN10 KPNB1 TOGARAM2 HEATR1 API5 HUWE1 ATAD2 WDFY4 SERAC1	8.92e-04	270	283	12	IPR011989
Domain	AMP-dep_Synth/Lig	ACSM1 SLC27A4 ACSM2A ACSM2B	1.04e-03	30	283	4	IPR000873
Domain	AMP-binding	ACSM1 SLC27A4 ACSM2A ACSM2B	1.04e-03	30	283	4	PF00501
Domain	JMJC	KDM5B KDM4E KDM6A JMJD1C	1.33e-03	32	283	4	PS51184
Domain	JmjC_dom	KDM5B KDM4E KDM6A JMJD1C	1.33e-03	32	283	4	IPR003347
Domain	-	C4A C5	1.35e-03	4	283	2	1.20.91.20
Domain	VPS13_C	VPS13C VPS13B	1.35e-03	4	283	2	IPR031645
Domain	ANKRD13	ANKRD13D ANKRD13A	1.35e-03	4	283	2	IPR021832
Domain	DNA_mis_repair	PMS1 PMS2	1.35e-03	4	283	2	PF01119
Domain	KCL_cotranspt	SLC12A6 SLC12A7	1.35e-03	4	283	2	IPR000076
Domain	SHR-BD	VPS13C VPS13B	1.35e-03	4	283	2	IPR009543
Domain	GPCR_chapero_1	ANKRD13D ANKRD13A	1.35e-03	4	283	2	PF11904
Domain	DNA_MISMATCH_REPAIR_1	PMS1 PMS2	1.35e-03	4	283	2	PS00058
Domain	DNA_mismatch_repair_C	PMS1 PMS2	1.35e-03	4	283	2	IPR013507
Domain	VPS13_C	VPS13C VPS13B	1.35e-03	4	283	2	PF16909
Domain	DNA_mismatch_repair_fam	PMS1 PMS2	1.35e-03	4	283	2	IPR002099
Domain	SHR-BD	VPS13C VPS13B	1.35e-03	4	283	2	PF06650
Domain	C2	WWC3 INPP4A SYT9 INPP4B FER1L6 SYT3 SYT10 PKN2	1.47e-03	142	283	8	PS50004
Domain	JmjC	KDM5B KDM4E KDM6A JMJD1C	1.49e-03	33	283	4	SM00558
Domain	AP_mu_sigma_su	AP2M1 AP3M2 AP3M1	1.67e-03	16	283	3	IPR022775
Domain	Clat_adaptor_s	AP2M1 AP3M2 AP3M1	1.67e-03	16	283	3	PF01217
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SAMD9 RAD54L2 RECQL4 ANTXR1 C4A C4B EXOC7 PZP TASOR CLEC16A SLC27A4 PMS1 POLE JMJD1C LIG4 SLC30A5 PRCC OGFOD1 PARN EIF2AK4 CLSPN SLC12A7 RPL3 RSBN1L TOP3A	3.57e-10	650	292	25	38777146
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZSWIM8 KDM5B MYCBP2 GPR37L1 EXTL3 RAD54L2 NAA25 AP2M1 SACS MTMR2 PPME1 CHD6 ATXN10 EXOC7 KDM6A USP47 KPNB1 PMS2 ANK3 GRIN2B HUWE1 NFE2L3 CNPPD1 THAP4 GMCL1 FRY POLR3B ARHGEF10 GUCY1B1 COPS4 TNKS METTL8 ST18 RSBN1L JPH3	1.13e-09	1285	292	35	35914814
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	MYCBP2 VPS4A PSMD11 SORT1 MDN1 TFB2M EXOC7 RAB2A CLEC16A EXOC6 SMARCA5 ISYNA1 SZT2 POLE ASCC1 HEATR1 HUWE1 METTL13 LAMTOR4 TAMM41 RAB2B CDK4	1.20e-08	606	292	22	36538041
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OBSCN AGO3 ZDBF2 CEP192 HUWE1 WDFY4 PCDHB16 GPR107 RAVER2 OGFOD1	1.46e-08	101	292	10	10997877
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	TP53INP1 EPHA6 MYCBP2 INPP4A VPS13C ACP3 DAB1 OBSCN TRRAP ADCY1 SHKBP1 ANTXR1 PPP1R9B CAB39L BOD1L1 CHD6 CLEC16A KDM6A DOCK1 PMS2P2 USP53 SLC12A6 ANK3 ATG7 CEP192 HUWE1 JMJD1C PCDHB16 THAP4 THRB RASGEF1C EIF2AK4 VPS13B KLHL26	1.43e-07	1489	292	34	28611215
Pubmed	Cloning, characterization and chromosomal assignment of the human genes homologous to yeast PMS1, a member of mismatch repair genes.	PMS1 PMS2P1 PMS2P2 PMS2P5	1.67e-07	7	292	4	7980603
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	MYCBP2 TRRAP MDN1 AGO3 SACS USP47 HUWE1 RPL3	2.58e-07	76	292	8	27542412
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	MYCBP2 PSMD11 SHKBP1 SORT1 HSPA12A UBA1 GANAB NFKB1 MTMR2 SNX27 PPME1 PRPF19 PPP1R9B ATXN10 KDM6A KPNB1 PMS1 PMS2 ANK3 CEP192 HUWE1 NDC1 PPP3CC VANGL1 EIF2AK4 SLC12A7 PTPN20	3.09e-07	1049	292	27	27880917
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	KNTC1 MYCBP2 VPS13C AP2M1 BOD1L1 TACC1 CHD6 EXOC7 TASOR SLC27A4 ZDBF2 HUWE1 JMJD1C ATL1 POLR3B SCAP ARHGEF10 GUCY1B1 VANGL1 TTLL4 CLSPN RSBN1L	3.25e-07	733	292	22	34672954
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	OBSCN PRAMEF1 ADGRE2 BRAF PAPOLA AGA MAP3K9 SNX27 BOD1L1 TFB2M CPLANE1 RAB2A TASOR LARGE2 PMS2 SCRN3 ANK3 CEP192 HEATR1 HUWE1 AP3M1 WDFY4 SCAP TTLL4 EIF2AK4 CCDC171 VPS13B	5.83e-07	1084	292	27	11544199
Pubmed	Mouse complement component C4 is devoid of classical pathway C5 convertase subunit activity.	C4A C4B C5	5.86e-07	3	292	3	8649451
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 NOC2L VPS4A VPS13C PSMD11 USP19 UBA1 AP2M1 GANAB MDN1 PRPF19 UTP20 BOD1L1 ATXN10 FAR1 RAB2A SLC27A4 KPNB1 SMARCA5 POLE HEATR1 API5 HUWE1 ATAD2 METTL13 NDC1 SMC3 COPS4 SPEN RPL3 CDK4	1.46e-06	1425	292	31	30948266
Pubmed	Genomic organization of the human PMS2 gene family.	PMS2P1 PMS2P2 PMS2P5 PMS2	1.53e-06	11	292	4	8586419
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	KNTC1 MYCBP2 NOC2L PSMD11 TRRAP SORT1 NAA25 TTBK1 GANAB BRAF PRPF19 CAB39L SPOP ATXN10 FAR1 SLC27A4 POLE HEATR1 JMJD1C LGALS3BP MRPS7 LIG4 METTL13 SMC3 GYS1 COPS4 RPL3 JPH3 CDK4	1.57e-06	1284	292	29	17353931
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	KDM5B MYCBP2 VPS4A PSMD11 TRRAP USP19 SHKBP1 GLDC SNX27 PPP1R9B USP47 USP50 USP53 CEP192 HUWE1 AP3M1 POLR3B SMC3 ARHGEF10 GYS1 COPS4 SASS6 TNKS PKN2 EIF2AK4	1.59e-06	1005	292	25	19615732
Pubmed	Mapping the Genetic Landscape of Human Cells.	NOC2L VPS4A TRRAP NAA25 MBTPS2 BOD1L1 ATXN10 TASOR POLE MTERF3 CEP192 POLR3B COPS4 OGFOD1 CLSPN RPL3	1.65e-06	451	292	16	30033366
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	NOC2L VPS4A PSMD11 PLXNB2 USP19 SORT1 NAA25 GANAB UTP20 ATXN10 FAR1 EXOC7 SLC27A4 KPNB1 EXOC6 POLE HEATR1 HUWE1 AP3M1 ANKRD13A SCAP NDC1 SMC3 CDK4	1.72e-06	942	292	24	31073040
Pubmed	Impaired mast cell-dependent natural immunity in complement C3-deficient mice.	C4A C4B C5	2.33e-06	4	292	3	9367154
Pubmed	Phylogeny of the C3/C4/C5 complement-component gene family indicates that C5 diverged first.	C4A C4B C5	2.33e-06	4	292	3	8015436
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	ABCA4 NFKB1 UCP3 AGTR1 SCNN1G C5 GPR132 APCS SLC2A4 SCAP MTRR	4.29e-06	229	292	11	19948975
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	OBSCN TRRAP MDN1 AGA C4A C4B SMARCA5 ANK3 TOGARAM2 ASCC1 AP3M1 SMC3 COPS4 EIF2AK4 HYDIN RSBN1L	5.68e-06	497	292	16	36774506
Pubmed	Role of complement receptors 1 and 2 (CD35 and CD21), C3, C4, and C5 in survival by mice of Staphylococcus aureus bacteremia.	C4A C4B C5	5.79e-06	5	292	3	15192652
Pubmed	Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies.	C4A C4B C5	5.79e-06	5	292	3	17200182
Pubmed	Intranasal peptide-induced tolerance and linked suppression: consequences of complement deficiency.	C4A C4B C5	5.79e-06	5	292	3	25039245
Pubmed	Formation of high affinity C5 convertase of the classical pathway of complement.	C4A C4B C5	5.79e-06	5	292	3	12878586
Pubmed	Predominant role for C5b-9 in renal ischemia/reperfusion injury.	C4A C4B C5	5.79e-06	5	292	3	10811844
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	ABCA4 PDE6A BCORL1 FER1L6 MDN1 CHD6 C5 KDM6A USP47 EXOC6 POLE ZDBF2 AP3M1 ABCC6 MRPS7 GYS1 OTOP1 SPEN	9.09e-06	638	292	18	31182584
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	ACP3 PSMD11 SHKBP1 AP2M1 GANAB MTMR2 SNX27 ATXN10 FAR1 SLC27A4 USP47 KPNB1 POLE HEATR1 HUWE1 PTOV1 ANKRD13A MRPS7 SMC3 VANGL1 TNKS RPL3 PTPN20	9.76e-06	974	292	23	28675297
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP19 GANAB MFN2 SNX27 BOD1L1 CHD6 CLEC16A DLGAP4 CEP192 PCDHB16 OGFOD1 SPEN ST18 VPS13B	1.05e-05	407	292	14	12693553
Pubmed	Complement activation via alternative pathway is critical in the development of laser-induced choroidal neovascularization: role of factor B and factor H.	C4A C4B C5	1.15e-05	6	292	3	16849499
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	KDM5B NFKB1 TACC1 USP47 DOCK1 VANGL1 TNKS CLSPN	1.34e-05	128	292	8	25332235
Pubmed	Subunit-specific regulation of NMDA receptor endocytosis.	AP2M1 GRIN2B AP3M1	2.00e-05	7	292	3	15254094
Pubmed	Complement C5a receptors and neutrophils mediate fetal injury in the antiphospholipid syndrome.	C4A C4B C5	2.00e-05	7	292	3	14660741
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	MYCBP2 NOC2L PSMD11 PLXNB2 TRRAP UBA1 GANAB MDN1 SACS PRPF19 UTP20 ATXN10 FAR1 KPNB1 SMARCA5 HEATR1 HUWE1 LGALS3BP NDC1 SMC3 VANGL1 SPEN RPL3	2.15e-05	1024	292	23	24711643
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	KNTC1 FAT2 AP2M1 TTBK1 SACS KCNS2 EXOC7 TASOR WDFY4 JMJD1C METTL13 SCAP TLR1 UNC80 SCN3B	2.15e-05	493	292	15	15368895
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	EPHA6 INPP4A ACSM1 TRRAP USP19 UBA1 GANAB MBTPS2 OSGEPL1 MFN2 PPME1 SPOP RAB2A SZT2 ZDBF2 HEATR1 ATAD2 GPR107 SCAP THRB LAMTOR4 TAMM41 SMC3 PARN EIF2AK4 CLSPN CDK4	2.35e-05	1327	292	27	32694731
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	MYCBP2 VPS4A PSMD11 FBXL3 UBA1 AP2M1 GANAB MDN1 MFN2 PRPF19 ATXN10 TFB2M FAR1 SLC27A4 KPNB1 ISYNA1 POLE HUWE1 AP3M1 LGALS3BP PTOV1 MRPS7 METTL13 SMC3 RPL3 CDK4	2.54e-05	1257	292	26	37317656
Pubmed	Constitutive expression of TNF-alpha and -beta genes in mouse embryo: roles of cytokines as regulator and effector on development.	NFKB1 C4A C4B C5	2.60e-05	21	292	4	8138038
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	MAG SERPINB7 KNTC1 VPS13C DAB1 OBSCN PSMD11 PRAMEF1 SORT1 ATXN10 FAR1 CPLANE1 TCTN1 KPNB1 CRISPLD2 ITGA11	2.68e-05	564	292	16	21565611
Pubmed	A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.	UBA1 NFKB1 TACC1 USP47 DOCK1 ISYNA1 POLE MTERF3 HUWE1 CLSPN	2.97e-05	232	292	10	25515538
Pubmed	C3 opsonization regulates endocytic handling of apoptotic cells resulting in enhanced T-cell responses to cargo-derived antigens.	C4A C4B C5	3.18e-05	8	292	3	24474777
Pubmed	Synergy between the classical and alternative pathways of complement is essential for conferring effective protection against the pandemic influenza A(H1N1) 2009 virus infection.	C4A C4B C5	3.18e-05	8	292	3	28301559
Pubmed	The role of complement in cryoglobulin-induced immune complex glomerulonephritis.	C4A C4B C5	3.18e-05	8	292	3	16272350
Pubmed	Sidekick 2 directs formation of a retinal circuit that detects differential motion.	DAB1 SYN1 SDK1 SDK2	3.80e-05	23	292	4	26287463
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	UBA1 MDN1 SACS PRPF19 TFB2M SLC27A4 POLE HUWE1 ATAD2 PPP3CC RAB2B PKN2 TOP3A	3.89e-05	400	292	13	35013556
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 MYCBP2 NOC2L TRRAP GANAB MDN1 UTP20 USP47 KPNB1 SMARCA5 POLE HEATR1 HUWE1 ATAD2 PARN SPEN RPL3	4.42e-05	653	292	17	22586326
Pubmed	Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.	SYT9 SYT3 SYT10	4.74e-05	9	292	3	10531343
Pubmed	Loss of K-Cl co-transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold.	MAG SLC12A6 SLC12A7	4.74e-05	9	292	3	14532115
Pubmed	RUTBC1 protein, a Rab9A effector that activates GTP hydrolysis by Rab32 and Rab33B proteins.	RAB32 RAB2A RAB2B	4.74e-05	9	292	3	21808068
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	VPS13C BOD1L1 CHD6 CEP126 USP53 JMJD1C LRRC8A EIF2AK4	4.85e-05	153	292	8	10718198
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	PSMD11 AP3M2 USP47 KPNB1 AP3M1 GYS1 COPS4 RPL3	5.56e-05	156	292	8	22952844
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ABCA4 KDM4E PRAMEF1 PLXNB2 TRRAP IL22RA1 MDN1 AGO3 GLDC NFKB1 ATXN10 ZNF791 VWA5B1 ANKRD13D NECAB2 JMJD1C GPR107 ANKRD13A SMC3 VANGL1 TTLL4 OGFOD1 ST18 SCN3B PUS7L	5.65e-05	1242	292	25	30973865
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	MYCBP2 NOC2L PLXNB2 HSPA12A GANAB MDN1 SACS PRPF19 TACC1 ATXN10 FAR1 PMS1 ANK3 POLE MTERF3 ASCC1 CEP192 HEATR1 LGALS3BP MRPS7 NDC1 ARHGEF10 PRCC VANGL1 COPS4 PKN2 RPL3 VPS13B	6.42e-05	1487	292	28	33957083
Pubmed	Genetic susceptibility to distinct bladder cancer subphenotypes.	TNFRSF10A NFKB1 UCP3 HSD17B2 PMS1 PMS2 CASR SLC2A4 LIG4 MTRR TNKS ROS1 CDK4	6.54e-05	421	292	13	19692168
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PLXNB2 HSPA12A GANAB MTMR2 SLC12A6 ANK3 DLGAP4 NDC1 SLC30A5 TAMM41 ARHGEF10 VANGL1 SLC12A7	6.54e-05	421	292	13	36976175
Pubmed	Complement Inhibitor CRIg/FH Ameliorates Renal Ischemia Reperfusion Injury via Activation of PI3K/AKT Signaling.	C4A C4B C5	6.73e-05	10	292	3	30429287
Pubmed	Frequency of somatic BRAF mutations in melanocytic lesions from patients in a CDK4 melanoma family.	BRAF CDK4	7.03e-05	2	292	2	24256466
Pubmed	Molecular cloning and characterization of a novel human Rab ( Rab2B) gene.	RAB2A RAB2B	7.03e-05	2	292	2	12376746
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	7.03e-05	2	292	2	19062096
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	7.03e-05	2	292	2	17645767
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	7.03e-05	2	292	2	12207352
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	7.03e-05	2	292	2	27758680
Pubmed	Insulin responsiveness of glucose transporter 4 in 3T3-L1 cells depends on the presence of sortilin.	SORT1 SLC2A4	7.03e-05	2	292	2	23966466
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	7.03e-05	2	292	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	7.03e-05	2	292	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	7.03e-05	2	292	2	4216347
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	7.03e-05	2	292	2	8428773
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	7.03e-05	2	292	2	24638111
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	7.03e-05	2	292	2	21345967
Pubmed	The complement component C4 of mammals.	C4A C4B	7.03e-05	2	292	2	2302180
Pubmed	B-Raf associates with and activates the NHE1 isoform of the Na+/H+ exchanger.	BRAF SLC9A1	7.03e-05	2	292	2	21345796
Pubmed	Overexpression of GLUT4 in mice causes up-regulation of UCP3 mRNA in skeletal muscle.	UCP3 SLC2A4	7.03e-05	2	292	2	10222258
Pubmed	Expression, Localization and Functional Activity of the Major Na⁺/H⁺ Exchange Isoforms Expressed in the Intestinal Cell Line Caco-2BBe.	SLC9A1 SLC9A2	7.03e-05	2	292	2	30977986
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	7.03e-05	2	292	2	22151770
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	7.03e-05	2	292	2	29080553
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	7.03e-05	2	292	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	7.03e-05	2	292	2	17728371
Pubmed	Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.	RAB2A RAB2B	7.03e-05	2	292	2	28063257
Pubmed	Structure and organization of the C4 genes.	C4A C4B	7.03e-05	2	292	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	7.03e-05	2	292	2	6149581
Pubmed	BRAF mutations are associated with increased iron regulatory protein-2 expression in colorectal tumorigenesis.	IREB2 BRAF	7.03e-05	2	292	2	28281325
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	7.03e-05	2	292	2	3542363
Pubmed	Insulin regulates fusion of GLUT4 vesicles independent of Exo70-mediated tethering.	EXOC7 SLC2A4	7.03e-05	2	292	2	19155211
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	7.03e-05	2	292	2	2387317
Pubmed	Architecture of cell-cell adhesion mediated by sidekicks.	SDK1 SDK2	7.03e-05	2	292	2	30150416
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	7.03e-05	2	292	2	7365238
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	7.03e-05	2	292	2	17971360
Pubmed	Analysis of C4 and the C4 binding protein in the MRL/lpr mouse.	C4A C4B	7.03e-05	2	292	2	17971229
Pubmed	UNC80 mutation causes a syndrome of hypotonia, severe intellectual disability, dyskinesia and dysmorphism, similar to that caused by mutations in its interacting cation channel NALCN.	NALCN UNC80	7.03e-05	2	292	2	26545877
Pubmed	Plasma Complement 3 and Complement 4 Are Promising Biomarkers for Distinguishing NMOSD From MOGAD and Are Associated With the Blood-Brain-Barrier Disruption in NMOSD.	C4A C4B	7.03e-05	2	292	2	35898513
Pubmed	Borrelia burgdorferi outer surface protein C (OspC) binds complement component C4b and confers bloodstream survival.	C4A C4B	7.03e-05	2	292	2	28873507
Pubmed	miR-21 synergizes with BMP9 in osteogenic differentiation by activating the BMP9/Smad signaling pathway in murine multilineage cells.	GDF2 SMAD7	7.03e-05	2	292	2	26460584
Pubmed	Recombination of two homologous MHC class III genes of the mouse (C4 and Slp) that accounts for the loss of testosterone dependence of sex-limited protein expression.	C4A C4B	7.03e-05	2	292	2	3794341
Pubmed	Fine-tuned characterization of RCCX copy number variants and their relationship with extended MHC haplotypes.	C4A C4B	7.03e-05	2	292	2	22785613
Pubmed	Association between complement 4 copy number variation and systemic lupus erythematosus: a meta-analysis.	C4A C4B	7.03e-05	2	292	2	32691186
Pubmed	Palmitate-induced down-regulation of sortilin and impaired GLUT4 trafficking in C2C12 myotubes.	SORT1 SLC2A4	7.03e-05	2	292	2	20805226
Pubmed	The androgen-dependent C4-Slp gene is driven by a constitutively competent promoter.	C4A C4B	7.03e-05	2	292	2	8390682
Pubmed	Structure and expression of murine fourth complement component (C4) and sex-limited protein (Slp).	C4A C4B	7.03e-05	2	292	2	3902619
Pubmed	Novel PMS2 pseudogenes can conceal recessive mutations causing a distinctive childhood cancer syndrome.	PMS2P1 PMS2	7.03e-05	2	292	2	15077197
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	7.03e-05	2	292	2	7373044
Interaction	CD70 interactions	EXTL3 TNFRSF10A SORT1 MDN1 UTP20 ATXN10 TFB2M EXOC7 EXOC6 HEATR1 METTL13 SLC30A5 TAMM41	6.67e-07	166	283	13	int:CD70
Interaction	SLC12A4 interactions	TNFRSF10A TRRAP SNX27 RAB2A SLC12A6 AP3M1 PCDHB16 RXFP1 SLC12A7 CLRN2	1.44e-05	129	283	10	int:SLC12A4
Interaction	ATOH1 interactions	MYCBP2 TRRAP MDN1 AGO3 SACS USP47 HUWE1 RPL3	1.66e-05	80	283	8	int:ATOH1
Interaction	KLRC1 interactions	GCNT1 PLXNB2 MDN1 ST3GAL6 AP3M2 ATXN10 TFB2M LARGE2 CHST10 AP3M1 CLRN2	2.00e-05	163	283	11	int:KLRC1
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B C5 PZP	1.79e-06	9	201	4	1234
GeneFamily	Fibronectin type III domain containing	EPHA6 OBSCN PTPRQ USH2A SDK1 SDK2 TRIM42 FSD1 LRRN3 ROS1	1.24e-05	160	201	10	555
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5B KDM4E KDM6A JMJD1C	1.32e-04	24	201	4	485
GeneFamily	Acyl-CoA synthetase family	ACSM1 SLC27A4 ACSM2A ACSM2B	1.83e-04	26	201	4	40
GeneFamily	MutL homologs	PMS1 PMS2	7.27e-04	4	201	2	1027
GeneFamily	Synaptotagmins	SYT9 SYT3 SYT10	8.21e-04	17	201	3	765
GeneFamily	CD molecules\|Adhesion G protein-coupled receptors, subfamily E	ADGRE2 ADGRE4P	1.20e-03	5	201	2	915
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC3 SMC1B	2.49e-03	7	201	2	761
GeneFamily	Schlafen family	SLFN14 SLFN13	2.49e-03	7	201	2	1110
GeneFamily	Glutamate ionotropic receptor NMDA type subunits	GRIN3B GRIN2B	2.49e-03	7	201	2	1201
GeneFamily	AAA ATPases	VPS4A MDN1 ATAD2 IQCA1	2.84e-03	53	201	4	413
GeneFamily	Cohesin complex	SMC3 SMC1B	3.30e-03	8	201	2	1060
GeneFamily	Ubiquitin specific peptidases	USP19 USP47 USP50 USP53	3.47e-03	56	201	4	366
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	NOC2L SACS PPP1R9B TRIM42 CEP192 SLC9A1 HYDIN	4.18e-03	181	201	7	694
GeneFamily	Exocyst complex	EXOC7 EXOC6	4.21e-03	9	201	2	1055
GeneFamily	Glycosyltransferase family 8	LARGE2 GXYLT1	4.21e-03	9	201	2	436
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	KNTC1 VPS13C PSMD11 TBCEL POLE GXYLT1 ATAD2 THRB PRCC TTLL4 TNKS	5.50e-06	180	289	11	M8239
Coexpression	KAUFFMANN_DNA_REPAIR_GENES	UBA1 RECQL4 PMS1 PMS2P1 PMS2P2 PMS2P5 PMS2 POLE LIG4 SMC3 TOP3A SMC1B	1.04e-05	230	289	12	M11563
Coexpression	GSE22611_NOD2_TRANSD_VS_CTRL_TRANSD_HEK293_MDP_STIM_2H_UP	RAD54L2 GDF2 PAPOLA AP3M2 TASOR SCRN3 GPR107 MTRR VPS13B PUS7L JPH3	1.23e-05	196	289	11	M8161
Coexpression	GSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_3H_IFNG_STIM_UP	PSMD11 AGA UTP20 CAB39L KDM6A HEATR1 HUWE1 TTLL4 TLR1 RPL3	2.50e-05	174	289	10	M6296
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 BEST2 BCORL1 ADCY1 PTPRQ GRIN3B TOGARAM2 IQCA1 UBQLN3 ROS1 ST18	2.58e-09	142	291	11	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	Neuroendocrine-neuroendo-1\|World / Class top	KCNIP1 ADCY1 RUNDC3A TTBK1 UCP3 SYN1 ST8SIA5 VWA5B1 TG CELF3 ST18 UNC80	2.70e-09	180	291	12	50fdd182a083380899b5943cb5f55ffd77e2a7d4
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHA6 BEST2 PTPRQ USH2A POLE GRIN2B ROS1 ST18 HYDIN UNC80 ACSM2B	3.22e-09	145	291	11	96712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 BEST2 ADCY1 PTPRQ GRIN3B TOGARAM2 IQCA1 UBQLN3 ROS1 ST18	3.22e-08	141	291	10	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 BEST2 ADCY1 PTPRQ GRIN3B TOGARAM2 IQCA1 UBQLN3 ROS1 ST18	3.22e-08	141	291	10	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EPHA6 PTPRQ USH2A POLE GRIN2B ROS1 ST18 HYDIN UNC80 ACSM2B	1.20e-07	162	291	10	bf886e22ff2a20353499004b53f25fb9e6574896
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 OBSCN PTPRQ USH2A SDK1 GRIN2B ROS1 ST18 HYDIN UNC80	3.90e-07	184	291	10	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 OBSCN PTPRQ USH2A SDK1 GRIN2B ROS1 ST18 HYDIN UNC80	3.90e-07	184	291	10	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 OBSCN PTPRQ USH2A SDK1 GRIN2B ROS1 ST18 HYDIN UNC80	3.90e-07	184	291	10	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	LRRTM1 ADCY1 ADRB1 CEP126 ANK3 GRIN2B SYT10 FRY GUCY1B1 SCN3B	5.24e-07	190	291	10	6e92c78799f34b31d098854503c796edb0dc7f80
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ODAD1 CEP126 CPLANE1 PZP SDK1 TCTN1 CFAP47 ANK3 IQCA1 HYDIN	6.05e-07	193	291	10	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	KDM5B IREB2 GANAB MBTPS2 CPLANE1 SMARCA5 HUWE1 VANGL1 VPS13B PUS7L	6.05e-07	193	291	10	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODAD1 RHPN1 HSPA12A LRRIQ1 CEP126 GRIN3B CPLANE1 CFAP47 TOGARAM2 HYDIN	7.29e-07	197	291	10	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	ACSM1 WDR38 HSPA12A ADRB1 LRRIQ1 SDK1 CFAP47 TOGARAM2 RAVER2	1.53e-06	166	291	9	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 DAB1 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	2.15e-06	173	291	9	0ba64e5385fe714f876002520f8b5202809bf11e
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	INPP4B SDK2 LGALS3BP TG NFE2L3 RXFP1 SLC12A7 PRPH	2.42e-06	131	291	8	81efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCell	droplet-Lung-LUNG-30m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAB1 LRRIQ1 PZP ANK3 APCS IQCA1 SLC10A5 IGSF1 HYDIN	2.47e-06	176	291	9	5201f003192c033655ba47f0faf8c47a96eae03d
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNIP1 ADCY1 RUNDC3A CEP126 CASR CELF3 CBLN2 ST18 PRPH	2.84e-06	179	291	9	f93e81a3fd94adedb24a9db4ac1d53e275bbf8b5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 DAB1 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	2.98e-06	180	291	9	b6efdb4d319ef6f87f559acd974e5a71b06a2322
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG DAB1 GPR37L1 LRRTM1 HSPA12A ANK3 RASGEF1C OTOP1 UNC80	3.26e-06	182	291	9	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYT9 SCNN1G SDK1 ANK3 GRIN2B FRY SLC9A2 THRB PTPN20	3.41e-06	183	291	9	b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADRB1 AGA MFN2 ELAC1 SLC27A4 FRY LRRN3 ARHGEF10 SASS6	3.41e-06	183	291	9	3ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 DAB1 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	3.41e-06	183	291	9	e3ffef2b57dc5b96466dccc9cd54ba326ccf378a
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-lung_neuroendocrine_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT9 KCNIP1 IL22RA1 ADCY1 RUNDC3A ST8SIA5 CELF3 IGSF1 UNC80	3.72e-06	185	291	9	30263c558ee331e0879abcf8b4c2427ff05f9fe7
ToppCell	droplet-Lung-immune-endo-depleted-3m-Epithelial-Neuroendocrine\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SYT9 KCNIP1 IL22RA1 ADCY1 RUNDC3A ST8SIA5 CELF3 IGSF1 UNC80	3.72e-06	185	291	9	1b000ca11970db8f347eb97ff44605d562aea70a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYT9 GLDC SCNN1G SDK1 ANK3 GRIN2B FRY SLC9A2 THRB	4.07e-06	187	291	9	e3095455d2f255854f339f6b05fa87852af0700f
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Ciliated_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B CFAP47 TOGARAM2 IQCA1 HYDIN	4.43e-06	189	291	9	dc440015949a768188c67661b6be63b1ead1a0f0
ToppCell	Tracheal-10x5prime-Stromal-Schwann\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MAG DAB1 GPR37L1 LRRTM1 HSPA12A GLDC GRIN2B SYT10 IGSF1	5.95e-06	196	291	9	b6226163d9fc93ecfff2115bb74408303a000490
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LRRTM1 ADCY1 RUNDC3A KCNS2 USH2A NECAB2 CELF3 ST18 UNC80	5.95e-06	196	291	9	4bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RUNDC3A SNX7 FSD1 ATL1 LRRN3 CELF3 ST18 SCN3B PRPH	6.46e-06	198	291	9	328f1d5d8168e05edd301d3a0f2eb5c6cd1c67c8
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCNN1G SDK1 USP50 ANK3 ANKRD13A OTOP1 ROS1 PTPN20	6.95e-06	151	291	8	f4f7156b2c0cfc78fd1841e07c9915d97ced561f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DAB1 INPP4B SYN1 KCNS2 NDNF NECAB2 SYT3 SYT10 SCN3B	7.01e-06	200	291	9	2f481e2fd248c02a5aa2e0248c16808df142fed2
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B TCTN1 CFAP47 TOGARAM2 HYDIN	7.01e-06	200	291	9	cc906ff02fd335ff633b3b97afceb670494f910a
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron-Neuron-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DAB1 INPP4B SYN1 KCNS2 NDNF NECAB2 SYT3 SYT10 SCN3B	7.01e-06	200	291	9	bd4b9f6b37f4a3c960c4149cf0cfd2caf3327d2d
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B TCTN1 CFAP47 TOGARAM2 HYDIN	7.01e-06	200	291	9	873def69bf55ccbfc944bc10c5afc06be019c312
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-SST\|Neuronal / cells hierarchy compared to all cells using T-Statistic	EPHA6 DAB1 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	7.01e-06	200	291	9	53d5e427f0cbf5cf0b63efe4ec01da302f555704
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Cortical_neuron\|6m / Sample Type, Dataset, Time_group, and Cell type.	DAB1 ADCY1 RUNDC3A SYN1 ANK3 GRIN2B ATL1 CELF3 SCN3B	7.01e-06	200	291	9	6f7ff0533339fcc9d316f2c77334a79c1409ec4f
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B TCTN1 CFAP47 TOGARAM2 HYDIN	7.01e-06	200	291	9	79e59ab31d3d3385b1b072dc75508af9546c2e1b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Neuron\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DAB1 INPP4B SYN1 KCNS2 NDNF NECAB2 SYT3 SYT10 SCN3B	7.01e-06	200	291	9	dc674124475edf83908b51a4e1454bc2dc4f06fa
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Neuronal\|6m / Sample Type, Dataset, Time_group, and Cell type.	DAB1 ADCY1 RUNDC3A SYN1 ANK3 GRIN2B ATL1 CELF3 SCN3B	7.01e-06	200	291	9	cedbc47b1defb5973cf7ab6baaa2d6f2fd481f88
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEST2 RHPN1 WDR38 LRRIQ1 CEP126 USH2A TOGARAM2 HYDIN	8.02e-06	154	291	8	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BEST2 RHPN1 WDR38 LRRIQ1 CEP126 USH2A TOGARAM2 HYDIN	8.02e-06	154	291	8	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	368C-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DPEP1 NDNF POLE ATL1 FRY RAVER2 RXFP1 PRPH	8.82e-06	156	291	8	4877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell	368C-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	DPEP1 NDNF POLE ATL1 FRY RAVER2 RXFP1 PRPH	8.82e-06	156	291	8	1d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RHPN1 LRRIQ1 RECQL4 CFAP47 CCDC73 SYT10 CCDC171 HYDIN	9.24e-06	157	291	8	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	LPS-antiTNF-Endothelial-Mes-Like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AP3M2 DNASE1L3 MTERF3 PLPP7 METTL13 VANGL1 RAVER2 RFLNA	9.68e-06	158	291	8	50df52d64d07178975563abd98ce4fddb9f2f7ef
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	INPP4A ADCY1 FER1L6 AGTR1 VWA5B1 CCNJL SDK2 SYT10	1.06e-05	160	291	8	174a4ab27114efcc63be36929b80680be3c35c9b
ToppCell	10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	KDM5B DOCK1 ISYNA1 SDK2 ATL1 LGALS3BP IQCA1 ST18	1.21e-05	163	291	8	edca1d1a345109dbdeb7ee5464faefab1993fdb2
ToppCell	10x5'-Lung-Lymphocytic_T_CD4/8-lo-Trm_Tgd\|Lung / Manually curated celltypes from each tissue	OSGEPL1 TCTN1 CCNJL FSD1 GMCL1 VANGL1 TNKS PUS7L	1.45e-05	167	291	8	dcbcc658082910838c8082d71a64917055086cc4
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MMP27 ADRB1 ADGRE4P SYN1 WDFY4 TLR1 SMC1B SCN3B	1.51e-05	168	291	8	04e168fe1d6f5f9e3d3bf9d7c13e800e3594868a
ToppCell	facs-Trachea-nan-24m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG GPR37L1 ADCY1 CASR ZDBF2 SLC9A2 CELF3 ST18	1.51e-05	168	291	8	6c7b490b6c844d0ea4c07edfc24c02284f9533c4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 DAB1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	1.87e-05	173	291	8	af85fb9f6e26a044ca4d23e5872039b1a7b73b1b
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHKBP1 ADGRE4P SCNN1G HSD17B2 ELAC1 USP47 METTL8 JPH3	1.87e-05	173	291	8	c31076c725f4cd912c56903592a2d9356ae59f54
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SHKBP1 ADGRE4P SCNN1G HSD17B2 ELAC1 USP47 METTL8 JPH3	1.87e-05	173	291	8	a4ed191cfdf6588b7f3672995bf0a4fe9e4b8df6
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG NOC2L DAB1 GPR37L1 RAD54L2 ANK3 TTLL4 RASGEF1C	1.95e-05	174	291	8	6987fe7959afce347282f632abc16d800ccab7c4
ToppCell	5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY1 RUNDC3A ST8SIA5 SDK2 CASR CELF3 CBLN2 ST18	2.03e-05	175	291	8	182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-neuro-epithelial-N_cells_(NTS+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SYT9 RUNDC3A AGTR1 SYN1 CELF3 RFLNA ST18 SCN3B	2.03e-05	175	291	8	97a58bc6ed2e8e359283d4214172c990c6e3755e
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GPR179 ZDBF2 RTL1 CELF3 TTLL4 OGFOD1 ST18 KLHL26	2.20e-05	177	291	8	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	droplet-Fat-Bat-18m-Endothelial-endothelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP11 EXOC7 CCNJL SDK2 ATL1 SERAC1 EIF2AK4 KLHL26	2.39e-05	179	291	8	e6224864eb76a2e9c1fc0c61513d9e936bb5c72c
ToppCell	3'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KCNIP1 ADCY1 RUNDC3A USH2A CASR PTOV1 CBLN2 ST18	2.39e-05	179	291	8	878b15ea62e3405682a538f79f58d74b9cd3f398
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_SST_CXCL14\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 DAB1 KCNIP1 INPP4B SDK1 SDK2 NECAB2 SYT10	2.39e-05	179	291	8	c7afbd10072d36a35cd20ae73670d76b9cefd22d
ToppCell	droplet-Fat-Bat-18m-Endothelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP11 EXOC7 CCNJL SDK2 ATL1 SERAC1 EIF2AK4 KLHL26	2.39e-05	179	291	8	dfe110add7228cd834b35916cbcc849769a01bb9
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A TASOR ANKRD13D ATL1 MICU3 OIT3 ARHGEF10 GYS1	2.39e-05	179	291	8	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	Ciliated_cells-A-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B PZP TOGARAM2 HYDIN	2.39e-05	179	291	8	0e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DNASE1L3 PMS2 SZT2 WDFY4 MICU3 TTLL4 CLSPN PUS7L	2.39e-05	179	291	8	9dea57494d59abd6e8abf34e31faf53462ea0fa0
ToppCell	droplet-Fat-Bat-18m-Endothelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AQP11 EXOC7 CCNJL SDK2 ATL1 SERAC1 EIF2AK4 KLHL26	2.39e-05	179	291	8	9863ab3ceb160a4b1d9790033a4ac48845863d65
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	ODAD1 WDR38 HSPA12A LRRIQ1 CEP126 CFAP47 TOGARAM2 HYDIN	2.49e-05	180	291	8	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DAB1 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	2.69e-05	182	291	8	7dc61e901428cea04f00ebb0939a44d21a6145c6
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG GPR37L1 LRRTM1 HSPA12A ANK3 RASGEF1C OTOP1 UNC80	2.69e-05	182	291	8	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG GPR37L1 LRRTM1 HSPA12A ANK3 RASGEF1C OTOP1 UNC80	2.69e-05	182	291	8	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG DAB1 GPR37L1 ADCY1 ANK3 GRIN2B RASGEF1C OTOP1	2.69e-05	182	291	8	a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYT9 KCNIP1 ADCY1 RUNDC3A ST8SIA5 CELF3 IGSF1 UNC80	2.91e-05	184	291	8	e0e5a553fb8c0947679634396d20c2ca8455b932
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG DAB1 GPR37L1 LRRTM1 C4A LRRN3 RASGEF1C UNC80	2.91e-05	184	291	8	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	droplet-Lung-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYT9 KCNIP1 ADCY1 RUNDC3A ST8SIA5 CELF3 IGSF1 UNC80	2.91e-05	184	291	8	c3b848e1438a84b3fac8a4e40f3db478cc84d970
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	KNTC1 MYCBP2 VPS13C FAR1 HEATR1 HUWE1 NDC1 SPEN	3.02e-05	185	291	8	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 PDE6A GDF2 KCNIP1 TTBK1 ADRB1 GUCY1B1 PRPH	3.02e-05	185	291	8	10ddf38d908525b4258f9d2da8be4c56ebc08ff4
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B-Branch_B3_(IPAN)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BCORL1 RUNDC3A NECAB2 FSD1 FRY CELF3 SCN3B PRPH	3.02e-05	185	291	8	edb114487206e4e8df4c7878285df40f49b7fd64
ToppCell	facs-Heart-RA-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KNTC1 PDE6A GDF2 KCNIP1 TTBK1 ADRB1 GUCY1B1 PRPH	3.02e-05	185	291	8	c4ef8d9f8b9769e887daac4efd9dc05738b28ae2
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPHA6 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	3.02e-05	185	291	8	027020754dbf71b0034791f9a34ae795e3b85f81
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG GPR37L1 RHPN1 HSPA12A LRRN3 RASGEF1C OTOP1 UNC80	3.02e-05	185	291	8	11c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DAB1 KCNIP1 INPP4B SDK1 NDNF SDK2 NECAB2 SYT10	3.02e-05	185	291	8	08fad1e3c3cc5f1c3eb6629a49c094b628e75a92
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SLC28A3 BDKRB1 PTPRQ C4A C4B UBQLN3 CBLN2 RFLNA	3.14e-05	186	291	8	7812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	KNTC1 MYCBP2 VPS13C FAR1 HEATR1 HUWE1 NDC1 SPEN	3.14e-05	186	291	8	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADGRE2 INPP4B AGTR1 SDK1 CRISPLD2 ITGA11 ZDBF2 RXFP1	3.26e-05	187	291	8	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	Ciliated_cells-B-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B PZP TOGARAM2 HYDIN	3.26e-05	187	291	8	2b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-bladder_urothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM5B FAT2 GLDC SCNN1G HSD17B2 CCNJL NFE2L3 SLC12A7	3.26e-05	187	291	8	aa336fb568a24e12c0454265ddd71ed10a6614cf
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSM1 DAB2 GCNT1 GLDC DPEP1 ANK3 ASCC1 ACSM2B	3.39e-05	188	291	8	b483b4629695764568bcbd1d527d614824147783
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INPP4A KCNIP1 RUNDC3A AGA LGALS3BP PTOV1 MICU3 CELF3	3.39e-05	188	291	8	63773854bf8430fb8229edb385b953a89833d08c
ToppCell	facs-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACSM1 DAB2 GCNT1 GLDC DPEP1 ANK3 ASCC1 ACSM2B	3.39e-05	188	291	8	c1f64311ff05093b2f4f672e33f5f75e3bc8a8db
ToppCell	facs-Trachea-nan-3m-Mesenchymal-smooth_muscle_cell_of_trachea\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR37L1 SORT1 ANK3 CASR ZDBF2 SLC2A4 GUCY1B1 RASGEF1C	3.39e-05	188	291	8	794fc1d9a726945c42f7eac221eed938309b47a9
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYT9 GLDC SCNN1G SDK1 ANK3 GRIN2B FRY SLC9A2	3.52e-05	189	291	8	3a295c215b5c18e7c673f92b7af5be523421682c
ToppCell	renal_cortex_nuclei-Adult_normal_reference\|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	NEDD9 BOD1L1 TACC1 USP53 DPEP1 ANK3 ST18 ACSM2B	3.52e-05	189	291	8	a48df46274d51e84ffb40264646de7346104efb9
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG DAB1 GPR37L1 SORT1 RHPN1 ST8SIA5 TCTN1 PRPH	3.52e-05	189	291	8	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	EPHA6 LRRIQ1 SCNN1G CFAP47 ANK3 ABCC6 FRY THRB	3.52e-05	189	291	8	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KCNIP1 GLDC GRIN2B ATAD2 SLC9A2 CLSPN JPH3	3.63e-05	139	291	7	c9bf98bed77415a1438f3f9e441a1346e75c26b0
ToppCell	Ciliated_cells-B\|World / lung cells shred on cell class, cell subclass, sample id	ODAD1 WDR38 LRRIQ1 CEP126 GRIN3B TOGARAM2 SLFN13 HYDIN	3.65e-05	190	291	8	7031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCell	droplet-Limb_Muscle-nan-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAG GPR37L1 RHPN1 HSPA12A LRRN3 RASGEF1C OTOP1 UNC80	3.65e-05	190	291	8	e2481bd5166fde2cdc0c3824894f2bccb8294fdd
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	KNTC1 MYCBP2 VPS13C FAR1 HEATR1 HUWE1 NDC1 SPEN	3.79e-05	191	291	8	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST8SIA5 SDK1 POLE FSD1 ATAD2 GUCY1B1 RAVER2 CLSPN	3.79e-05	191	291	8	c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L6b\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	INPP4B ANTXR1 HSD17B2 GABRR3 SDK2 LGALS3BP NFE2L3	3.80e-05	140	291	7	17005ca714ba03d7528fe7979ffb4654a46b666c
Drug	NSC236997	MMP27 IREB2 PBLD EXTL3 RAD54L2 ADCY1 BDKRB1 USP19 SORT1 NAA25 ADRB1 NFKB1 UCP3 AGTR1 ELAC1 CLEC16A POLE SLC2A4 SLC9A1 THRB GYS1 TNKS DSEL SMAD7	1.44e-07	539	292	24	CID000005300
Disease	Malignant neoplasm of endometrium	SPOP PMS1 PMS2 POLE	2.25e-05	18	282	4	C0007103
Disease	Carcinoma in situ of endometrium	SPOP PMS1 PMS2 POLE	2.25e-05	18	282	4	C0346191
Disease	Colorectal Carcinoma	ABCA4 OBSCN SYT9 BRAF SACS SCNN1G PZP KDM6A DNASE1L3 DPEP1 PMS2 POLE ABCC6 CNPPD1 MTRR DSEL SCN3B JPH3 SMAD7	5.24e-05	702	282	19	C0009402
Disease	Amyotrophy, monomelic	CEP126 CPLANE1	9.10e-05	2	282	2	C1865384
Disease	X-21319 measurement	ACSM2A ACSM2B	9.10e-05	2	282	2	EFO_0800807
Disease	Alzheimer's disease biomarker measurement	DAB1 GLDC ARHGEF10 CERS3 RASGEF1C	9.41e-05	48	282	5	EFO_0006514
Disease	Charcot-Marie-Tooth disease (is_implicated_in)	MFN2 SLC12A6 POLR3B	1.78e-04	12	282	3	DOID:10595 (is_implicated_in)
Disease	Alzheimer disease	DAB1 SORT1 SNX7 MTMR2 ANTXR1 SDK1 USP50 PMS2P1 ANK3 GRIN2B LIG4 RASGEF1C CCDC171 ST18	2.66e-04	485	282	14	MONDO_0004975
Disease	picolinate measurement	DPEP1 ACSM2B	2.71e-04	3	282	2	EFO_0800115
Disease	Cohen syndrome (implicated_via_orthology)	VPS13C VPS13B	2.71e-04	3	282	2	DOID:0111590 (implicated_via_orthology)
Disease	X-11478 measurement	ACSM2A ACSM2B	2.71e-04	3	282	2	EFO_0021242
Disease	Adenocarcinoma of large intestine	TRRAP BRAF PMS1 PMS2 POLE ROS1	3.26e-04	96	282	6	C1319315
Disease	Intellectual Disability	INPP4A TRRAP FBXL3 AP2M1 SACS SNX27 TFB2M TCTN1 GRIN2B ATL1 FRY POLR3B SERAC1	4.08e-04	447	282	13	C3714756
Disease	Endometrial Carcinoma	SPOP HSD17B2 PMS1 PMS2 POLE	6.38e-04	72	282	5	C0476089
Disease	Ciliopathies	SPATA7 SCNN1G ATXN10 CPLANE1 USH2A TCTN1	6.74e-04	110	282	6	C4277690
Disease	nephrolithiasis (implicated_via_orthology)	SLC9A1 SLC9A2	8.93e-04	5	282	2	DOID:585 (implicated_via_orthology)
Disease	phospholipase B-like 1 measurement	MFN2 COPS4	8.93e-04	5	282	2	EFO_0802865
Disease	SYSTEMIC LUPUS ERYTHEMATOSUS 16	C4A DNASE1L3	8.93e-04	5	282	2	C3280742
Disease	Retinal Dystrophy, Early Onset Severe	SPATA7 ABCA4	8.93e-04	5	282	2	C1858080
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	8.93e-04	5	282	2	EFO_0800378
Disease	myocardial infarction (biomarker_via_orthology)	DAB2 BDKRB1 AGTR1 MFN2 KDM6A ATG7 CASR	9.10e-04	160	282	7	DOID:5844 (biomarker_via_orthology)
Disease	Disorder of eye	SPATA7 ABCA4 PDE6A GPR179 MFN2 CPLANE1 USH2A TCTN1	1.04e-03	212	282	8	C0015397
Disease	colorectal cancer (is_implicated_in)	BRAF SPOP KDM6A POLE LIG4 SMAD7	1.11e-03	121	282	6	DOID:9256 (is_implicated_in)
Disease	indoleacetylglutamine measurement	ACSM1 ACSM2A	1.33e-03	6	282	2	EFO_0800035
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	1.33e-03	6	282	2	EFO_0800106
Disease	unipolar depression, environmental factor	ASCC1 RFLNA	1.33e-03	6	282	2	EFO_0000469, EFO_0003761
Disease	Bladder Neoplasm	INPP4B CHD6 KDM6A PPP3CC SLC12A7 SMC1B	2.33e-03	140	282	6	C0005695
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	VPS4A GRIN2B THRB	2.37e-03	28	282	3	DOID:1094 (implicated_via_orthology)
Disease	Malignant neoplasm of urinary bladder	INPP4B CHD6 KDM6A PPP3CC SLC12A7 SMC1B	2.41e-03	141	282	6	C0005684
Disease	Familial melanoma	BRAF CDK4	2.45e-03	8	282	2	cv:C1512419
Disease	Malignant melanoma of skin	BRAF CDK4	2.45e-03	8	282	2	cv:C0151779
Disease	40S ribosomal protein S4, X isoform measurement	SLFN14 JMJD1C	2.45e-03	8	282	2	EFO_0801334
Disease	Melanoma	BRAF CDK4	2.45e-03	8	282	2	cv:C0025202
Disease	Leprosy	RAB32 TLR1	2.45e-03	8	282	2	C0023343
Disease	placental insufficiency (biomarker_via_orthology)	AGTR1 GRIN2B	2.45e-03	8	282	2	DOID:3891 (biomarker_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of ovary	BRAF PMS1 PMS2	2.63e-03	29	282	3	C0496920
Disease	JT interval	OBSCN NFKB1 TASOR USP50 CASR SLC2A4 THRB SLC12A7	2.79e-03	248	282	8	EFO_0007885
Disease	Ovarian Carcinoma	BRAF PMS1 PMS2	2.90e-03	30	282	3	C0029925
Disease	familial melanoma (is_implicated_in)	BRAF CDK4	3.13e-03	9	282	2	DOID:6846 (is_implicated_in)
Disease	renovascular hypertension (implicated_via_orthology)	ADRB1 AGTR1	3.13e-03	9	282	2	DOID:1591 (implicated_via_orthology)
Disease	Large cell carcinoma of lung	TRRAP TTBK1 ROS1	3.49e-03	32	282	3	C0345958
Disease	Complement deficiency disease	C4A C4B C5	3.81e-03	33	282	3	C0272242
Disease	renal cell carcinoma (is_implicated_in)	TNFRSF10A C4A C4B THRB	4.34e-03	69	282	4	DOID:4450 (is_implicated_in)
Disease	pneumonia, COVID-19	DAB1 GRIN2B ST18 VPS13B UNC80	4.67e-03	113	282	5	EFO_0003106, MONDO_0100096
Disease	nephritis (biomarker_via_orthology)	SERPINB7 SMAD7	4.73e-03	11	282	2	DOID:10952 (biomarker_via_orthology)
Disease	Cleft palate, tobacco smoke exposure measurement, cleft lip, parental genotype effect measurement	SHKBP1 ANK3	4.73e-03	11	282	2	EFO_0003959, EFO_0005939, EFO_0009115, HP_0000175
Disease	Lupus Erythematosus, Systemic	C4A C4B CLEC16A DNASE1L3	4.80e-03	71	282	4	C0024141
Disease	cardiomyopathy (implicated_via_orthology)	BRAF CASR PPP3CC JPH3	4.80e-03	71	282	4	DOID:0050700 (implicated_via_orthology)
Disease	allergic disease, age at onset	SERPINB7 NFKB1 CLEC16A TLR1	4.80e-03	71	282	4	EFO_0004847, MONDO_0005271
Disease	electrocardiography	MYCBP2 DAB1 OBSCN ADRB1 SNX7 USP50 PLPP7 SYT10 JMJD1C THRB ROS1 SMAD7	5.31e-03	530	282	12	EFO_0004327
Disease	Colorectal Neoplasms	ABCA4 BRAF POLE ABCC6 CNPPD1 MTRR JPH3 SMAD7	5.40e-03	277	282	8	C0009404
Disease	prostate cancer (is_implicated_in)	ACP3 NFKB1 LIG4 THRB CDK4	5.41e-03	117	282	5	DOID:10283 (is_implicated_in)
Disease	asthma, endometriosis	PLXNB2 C5 SLC9A2 TNKS	5.56e-03	74	282	4	EFO_0001065, MONDO_0004979
Disease	Retinitis pigmentosa	SPATA7 ABCA4 PDE6A USH2A	5.56e-03	74	282	4	cv:C0035334
Disease	psychotic symptoms	DAB1 ANK3 WDFY4 ST18	5.56e-03	74	282	4	EFO_0005940
Disease	diastolic blood pressure, alcohol drinking	NAA25 ADRB1 TOGARAM2 GUCY1B1 TNKS	5.60e-03	118	282	5	EFO_0004329, EFO_0006336
Disease	endometrial carcinoma (is_implicated_in)	BRAF POLE	5.64e-03	12	282	2	DOID:2871 (is_implicated_in)
Disease	mismatch repair cancer syndrome (is_implicated_in)	PMS2 POLE	5.64e-03	12	282	2	DOID:0112182 (is_implicated_in)
Disease	prediabetes syndrome (biomarker_via_orthology)	UCP3 MFN2	5.64e-03	12	282	2	DOID:11716 (biomarker_via_orthology)
Disease	immature platelet measurement	SLFN14 PPP1R9B JMJD1C SLC12A7 SEC14L5	5.80e-03	119	282	5	EFO_0803541
Disease	Graves' disease (is_implicated_in)	C4A C4B TG	6.12e-03	39	282	3	DOID:12361 (is_implicated_in)
Disease	platelet component distribution width	TP53INP1 SLFN14 INPP4B ADRB1 ANTXR1 PPP1R9B EXOC6 JMJD1C METTL13 THRB PKN2 EIF2AK4 ZNF333 SLC12A7 SEC14L5	6.42e-03	755	282	15	EFO_0007984
Disease	Lymphoma	BRAF LIG4 CDK4	6.57e-03	40	282	3	C0024299
Disease	Pulmonary Hypertension	GDF2 CBLN2 EIF2AK4	6.57e-03	40	282	3	C0020542
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	ADCY1 PTPRQ	6.62e-03	13	282	2	C1846647
Disease	Congenital Hypothyroidism	TG IGSF1	6.62e-03	13	282	2	C0010308
Disease	Cutaneous Melanoma	TRRAP BRAF CDK4	7.04e-03	41	282	3	C0151779
Disease	cardiac troponin I measurement	DAB1 PLXNB2 PZP ITGA11 AP3M1 JPH3	7.09e-03	176	282	6	EFO_0010071
Disease	rectum cancer	INPP4B WDFY4 SMAD7	7.53e-03	42	282	3	EFO_1000657
Disease	Multiple Myeloma	BRAF KDM6A LIG4	7.53e-03	42	282	3	C0026764
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	GDF2 EIF2AK4	7.68e-03	14	282	2	C1150929
Disease	longitudinal BMI measurement	SLC28A3 ADGRE4P DOCK1 NECAB2	7.97e-03	82	282	4	EFO_0005937
Disease	systemic lupus erythematosus (implicated_via_orthology)	C4A C4B ATG7	8.04e-03	43	282	3	DOID:9074 (implicated_via_orthology)
Disease	biliary liver cirrhosis	NFKB1 CLEC16A RPL3	8.57e-03	44	282	3	EFO_0004267
Disease	schizophrenia (is_marker_for)	PPP1R9B ANK3 PPP3CC	8.57e-03	44	282	3	DOID:5419 (is_marker_for)
Disease	high grade glioma (implicated_via_orthology)	BRAF ATG7 POLE	8.57e-03	44	282	3	DOID:3070 (implicated_via_orthology)
Disease	Generalized hypotonia	AP2M1 SNX27	8.80e-03	15	282	2	C1858120
Disease	hyperinsulinism (biomarker_via_orthology)	IREB2 AGTR1	8.80e-03	15	282	2	DOID:2018 (biomarker_via_orthology)
Disease	pancreatic adenocarcinoma (is_implicated_in)	CDK4 SMAD7	8.80e-03	15	282	2	DOID:4074 (is_implicated_in)
Disease	mean arterial pressure	NAA25 TTBK1 ADRB1 ATG7 SZT2 SLC2A4 SLC9A1 GUCY1B1 PRSS42P EIF2AK4 TOP3A	9.01e-03	499	282	11	EFO_0006340
Disease	Autism Spectrum Disorders	USH2A GRIN2B LRRN3 UNC80	9.03e-03	85	282	4	C1510586
Disease	Gastric Adenocarcinoma	TRRAP MAP3K9 ROS1	9.12e-03	45	282	3	C0278701

Protein segments in the cluster

Peptide	Gene	Start	Entry
HDFSKISIVRPFSIE	TACC1	141	O75410
FIDPKSHKFVLRLQS	VANGL1	506	Q8TAA9
KIHVPSQFFILITIT	PRO1854	51	Q9UHT4
RHEPLAKIILFSNQF	CAB39L	151	Q9H9S4
FLANVVKAFHRELVP	ADRB1	341	P08588
FAFRHPESIIELNLV	FAM200B	541	P0CF97
AVFKRFPTIDHVVEA	BEST2	146	Q8NFU1
VLENVPLTTHNFVRK	BRAF	226	P15056
PLTTHNFVRKTFFTL	BRAF	231	P15056
APISSSHRKEIFQLF	BDKRB1	336	P46663
KVRLQHFFTPEKSTV	ARHGEF10	1011	O15013
VPFGHVISAKVFVDR	CELF3	401	Q5SZQ8
EIPLFHVLNARITFS	ANKRD13D	411	Q6ZTN6
TQLARIADSKDHVFP	ANTXR1	186	Q9H6X2
AQPPRIFVAHSKFVI	NEDD9	736	Q14511
VATPVQLRVFREFHL	C4B	821	P0C0L5
EFNSLVKLSHPNVVR	EIF2AK4	346	Q9P2K8
TIRSHKDFLAQIVLP	ABCA4	1366	P78363
TFTFSHRSVIPRQKV	ADGRE2	466	Q9UHX3
PVFLRHAELIASTFV	ATXN10	266	Q9UBB4
LPAIIHRNVFFIENT	AGTR1	161	P30556
RVLLVFEAKIPTSFH	CASR	701	P41180
KAFVVLASQFLSHDP	ACSM2A	506	Q08AH3
FLKETFINTVPHALT	CCDC171	1291	Q6TFL3
TRREIFKLQFHSMPV	SPATA5	801	Q8NB90
FHLSSFAVLVALAPK	ADGRE4P	171	Q86SQ3
LKLSSRIFQARFPHF	BCORL1	1706	Q5H9F3
AHSPLLKSRRFFVDI	CCNJL	31	Q8IV13
LLDTFRRKQPFTHFL	ASCC1	151	Q8N9N2
VPLFSKNVHSTRFVT	API5	246	Q9BZZ5
QRVFPHAEFRTNKTL	ATAD2	721	Q6PL18
VQHFKVTIFGDRRPV	AGO3	71	Q9H9G7
ISFIDVLFRHTPAKT	RAD54L2	316	Q9Y4B4
VLFRHTPAKTVLAIV	RAD54L2	321	Q9Y4B4
PLFVIEFLHRVADTF	AP3M1	76	Q9Y2T2
HLVHSVQRLFFTKAP	DLGAP4	141	Q9Y2H0
RQIHKPLTAVEFITA	IQCA1	761	Q86XH1
TEQGKPFVSVFRHLR	GMCL1	321	Q96IK5
EELLQIFSSVHKPVF	RAVER2	246	Q9HCJ3
FTDKRFQPVHDLTIG	RAB2A	26	P61019
SVNKLFVRVFTVHPN	PZP	411	P20742
ETAFIRKLHPTDNFA	PBLD	46	P30039
FTDKRFQPVHDLTIG	RAB2B	26	Q8WUD1
RFLVEKILVNHQSFP	RAB32	186	Q13637
LPFTKSLSLVFHAID	GPR107	301	Q5VW38
ILSFFPVDNVTLKHL	IREB2	381	P48200
FLHFVEASPVLAARQ	LARGE2	471	Q8N3Y3
TATEDFPFQKHILLF	GDF2	121	Q9UK05
QTFHPVLSLLSFLFK	ISYNA1	451	Q9NPH2
ESVLSLHVPRQFVKL	INPP4A	251	Q96PE3
PDKVAEAVATFLIRH	PPME1	356	Q9Y570
IHVSARSKLIEPFFN	PARN	406	O95453
FPRTSSKLEHFVSIL	LRRC8A	146	Q8IWT6
IEIPLFHVLNARITF	ANKRD13A	411	Q8IZ07
RHKIFFVAVIQTEVP	AP3M2	61	P53677
PLFVIEFLHRVVDTF	AP3M2	76	P53677
AIPVYVKHNISFRDS	AP3M2	271	P53677
HPVNKISFIARDVTD	DAB2	116	P98082
KLVFFEVSPVSFHQV	OGFOD1	206	Q8N543
KHFPGISIRVDAAFQ	MMP27	416	Q9H306
HALTIRLTNKVEFPF	OSGEPL1	151	Q9H4B0
VHLQREKFTFAATRP	MDN1	641	Q9NU22
HVISTFKRNPLEQAF	FAR1	321	Q8WVX9
HFPEIFRKVSQRTEL	MAGEB4	146	O15481
KSQFPVILSRASEHL	MAGEB10	146	Q96LZ2
PVVFKSRTQVVHESF	MAG	71	P20916
KTLQALEFHTVPFQL	LGALS3BP	376	Q08380
LLSAAFHTARFVLVP	GPR179	586	Q6PRD1
LVKVNFAHFPRLISL	LRRTM1	221	Q86UE6
AAFHRTPSLLEQEVK	SLC2A4	481	P14672
KQVLHTFKTRFTQPL	FSD1	441	Q9BTV5
LFVHAFKDQLVRSAL	INPP4B	456	O15327
SPLIIDKNEHFTVYR	JMJD1C	701	Q15652
ILTHLKVSFSRDAPV	MTRR	601	Q9UBK8
HELTKLPAFVRVVSA	KDM6A	1101	O15550
VFHNDTKVVFLSPAV	PLXNB2	1046	O15031
TTHNLPEFIVKFGSR	PLXNB2	1166	O15031
DLNHFSGVISLKRPF	FAT2	611	Q9NYQ8
VLAFLNKRTDFHIPH	FCRL5	141	Q96RD9
SRNHGIFPFTLEIFK	OIT3	381	Q8WWZ8
KVVSVFHTVIFPLLN	OR4M1	271	Q8NGD0
RISVPVHSFASLNIK	PRPH	406	P41219
VVDKFHIPQEALVRF	PDE6A	531	P16499
VPFFVKSERHGVQSL	CRISPLD2	356	Q9H0B8
HFTLEKIQPRVISFE	COPS4	86	Q9BT78
RAKALHIPFSVDEIV	NFE2L3	541	Q9Y4A8
SAIIFSIKPLQFHIF	GXYLT1	136	Q4G148
VVVLPITLIFNKFSH	KCNS2	401	Q9ULS6
LFSTLPVRHKEFQRN	PMS2P5	56	A8MQ11
EAFLRHKVALISPTV	KDM4E	236	B2RXH2
KFLRFAPVSSHQKVT	NDNF	361	Q8TB73
AQSHKIFIFDARPSV	MTMR2	311	Q13614
ISFQPVFRQHFLTKK	KNTC1	1416	P50748
LSVFSLVRPHIDISF	GUCY1B1	251	Q02153
FAFIHKIRPIAEQTG	KDM5B	46	Q9UGL1
SPHLVNTVFKIFDVD	MICU3	471	Q86XE3
PVTNIARTSFFHVKR	AP2M1	46	Q96CW1
LAIFQAEPTVRKHFL	POLE	1096	Q07864
TTILLTPERKFHSFG	HSPA12A	101	O43301
INASLHFEPSKINIF	ITGA11	641	Q9UKX5
QLFSTLPVHHKEFQR	PMS2P1	361	A4D2B8
IQLAKVFPSHFTQQR	HUWE1	3341	Q7Z6Z7
TPKLFHEVVQAFRAA	NOC2L	166	Q9Y3T9
IFTHSKNVRSPGFIL	ODAD1	91	Q96M63
RSIFQVFTHLPGKVA	EXOC6	641	Q8TAG9
FSTVLTVFPILRHLK	EXOC7	426	Q9UPT5
VLKEDTPRQHVDVFF	KCNIP1	176	Q9NZI2
ISQNSLTKIVPLFHF	LRRIQ1	1066	Q96JM4
FHKVSERLSRPNIFI	MFN2	241	O95140
ENSAPLIHFVKLVRA	PTPRQ	2206	Q9UMZ3
VPLFRNSRLVQFHFT	PTOV1	316	Q86YD1
RLSFHLDVSEPKAVF	OBSCN	1336	Q5VST9
RPLIFNFHEQTAIKD	PTPN20	131	Q4JDL3
PNAIASTLVHKFFLV	PAPOLA	261	P51003
KVTSVVFHPSQDLVF	PRPF19	266	Q9UMS4
KFVTLVFRHGDRSPI	ACP3	36	P15309
KISPSSHFRVLIHEF	PCDHB16	171	Q9NRJ7
RSYFDLIVVDTQKPH	NT5DC4	246	Q86YG4
IIQSFKTLERFGVIH	OTOP1	191	Q7RTM1
TFRPQVEKAVHEFLA	BOD1L1	146	Q8NFC6
IETFFIVPSHRRKIF	ADCY1	471	Q08828
DFTFLPGHQKLSARI	CNPPD1	21	Q9BV87
TVLENFFKHSTRQPL	CERS3	81	Q8IU89
VPDIFFVHSKRSFIH	GABRR3	141	A8MPY1
RPSHKTFQVSFLIGA	IGSF1	81	Q8N6C5
VFKRSFQIQIAHLDP	HYDIN	1466	Q4G0P3
VLTINREAFPAHKVV	KLHL26	66	Q53HC5
IFHAARTPATLFVVI	ATL1	441	Q8WXF7
ARDVAHSIIFEVKLP	ATG7	276	O95352
VSDHFPVEFKLQSSR	DNASE1L3	271	Q13609
IADRKFQHFNPVLET	DOCK1	686	Q14185
HRFVAIKTAQAAEPV	DAB1	136	O75553
LTPFIHNAFKADIQI	LIG4	311	P49917
SFRLIPLQHSKVASV	CPLANE1	976	Q9H799
LAAQIHKESFLAPVF	CHD6	2156	Q8TD26
LTFNPHKRISAFRAL	CDK4	276	P11802
PKSHFISALTVVFVN	FBXL3	156	Q9UKT7
SVFIHQPRALTESKE	C7orf25	391	Q9BPX7
FEEVTEKFQRAHVPL	CEP126	111	Q9P2H0
IDRFHVATSTLPKVR	GPR37L1	226	O60883
QFRVDSVLFKTRLPH	EXTL3	896	O43909
THPQFRSIVSALKRE	C5	1201	P01031
FKSPNNHFVVLDTAI	CCDC73	531	Q6ZRK6
NHFDLASSIFVAPRK	CBLN2	126	Q8IUK8
LVPSKEQHLTFTREF	ANK3	941	Q12955
QPRVEFILSFIDHIA	KPNB1	791	Q14974
FVDLFTTHLQLISPV	MBTPS2	201	O43462
VPFKRLSVVFGEHTL	LAMTOR4	61	Q0VGL1
RIHPKEDIFISVLFA	CEP192	1831	Q8TEP8
SRIQKHFPEFFGAVI	AGA	291	P20933
RFIQEHVLIPVFDLS	IL22RA1	276	Q8N6P7
SSLKETHFPFAIRVF	HEATR1	716	Q9H583
THFPFAIRVFSLLQK	HEATR1	721	Q9H583
FQIFRALKQPLSAHA	FRY	1871	Q5TBA9
LITFSVLRIHQKPEF	GCNT1	26	Q02742
TVKPSRDNHFAIFII	METTL13	291	Q8N6R0
FNSSADRVKVIFHPE	GYS1	466	P13807
DRVKVIFHPEFLSST	GYS1	471	P13807
TIISIQFLSRFQHPK	FDXACB1	566	Q9BRP7
VLRDIQHAILAKSPF	HSD17B2	321	P37059
KATLQLSRAPVIFSH	DPEP1	221	P16444
DNIIPFLRVFGHSKA	SLC12A6	601	Q9UHW9
DAEQAVKHPRLLSFT	SLC12A7	701	Q9Y666
DVVFSLYHTKQAPRL	SEC14L5	546	O43304
NKTSPFIHLSIARDV	SDK1	271	Q7Z5N4
HNASSFIVDRLKPFT	SDK2	1456	Q58EX2
AFLNVVETNPFKHLT	SASS6	121	Q6UVJ0
HKNLLAVDVFRSPLS	SCAP	106	Q12770
VSVSIKVHFRKLDFP	SCNN1G	81	P51170
VISAHKNQDITLFPR	SACS	2836	Q9NZJ4
NVIARAISKLPIVHF	SLFN13	271	Q68D06
LNLSSTKFVFEIPLH	CFAP47	1191	Q6ZTR5
ITLPHFTNTALTFKV	CFAP47	2431	Q6ZTR5
LTEVLVIPKRNSHNF	CFAP47	2931	Q6ZTR5
VHFPQKTTERIFAFL	DSEL	1131	Q8IZU8
LVFVLSSIHPDRTLF	METTL8	276	Q9H825
ERSFIFINSRPVHQK	PMS1	256	P54277
NRISLPSDFQHKFTV	MAP3K9	516	P80192
VATPVQLRVFREFHL	C4A	821	P0C0L4
HIIVKFPQVFNTRLF	MTERF3	346	Q96E29
ERNHRPKFTDIVSFL	EPHA6	916	Q9UF33
PLSIIAFTNHRIFRS	GPR132	211	Q9UNW8
KLRVVTLLEHPFVFA	GRIN3B	416	O60391
FVEKIRFLVDEPQHT	FER1L6	701	Q2WGJ9
FAAILEQILSHRFKA	RUNDC3A	61	Q59EK9
HRQTVEFLGFVVTPK	RTL1	771	A6NKG5
FIPRNVVHQFKTVSA	RSBN1L	666	Q6PCB5
SVPLAELAQRKLHFS	SYT3	371	Q9BQG1
VHRKTLNPVFDEVFL	SYT9	276	Q86SS6
HTVALVIPFILFLAS	TAS2R16	181	Q9NYV7
HLGKTSLTVVFREPF	SZT2	3381	Q5T011
RSLKPDFVLIRQHAF	SYN1	176	P17600
IVTDLAVFTPHQFLL	USH2A	2106	O75445
IAHLQVFSKFSNPRA	UTP20	916	O75691
TIERNPYTIFHQALK	MRPS7	136	Q9Y2R9
AIEHSSRPINVIKFS	SORT1	536	Q99523
YRTSQPIKADVLFIH	SERAC1	386	Q96JX3
LHNLTPNTEYVFKVR	TRIM42	666	Q8IWZ5
FKEALQRHLFPVTQE	SLFN14	386	P0C7P3
VHAQFITTTFRPELL	SMC3	1166	Q9UQE7
TVKETNRLLLPHAFS	PRCC	191	Q92733
TAHLVQVFDAFTPRL	TOGARAM2	801	Q6ZUX3
ISFYDNRLIKVPHVA	LRRN3	241	Q9H3W5
ILNKAQAFLPFSIHS	ABCC6	576	O95255
QRASLHSAIRQKFPF	PUS7L	171	Q9H0K6
HSAIRQKFPFLVTVG	PUS7L	176	Q9H0K6
PRGLRTFKTVFAEHI	RPL3	96	P39023
PEEKFSSRAVARIFH	RECQL4	1151	O94761
KESRVANLHFPSVYV	SAMD9	456	Q5K651
RSVFKPFIFVPHISQ	SCRN3	306	Q0VDG4
QLFSTLPVRHKEFQR	PMS2P2	226	O95744
SFQHDPETSVLVLRK	GANAB	916	Q14697
PFSRVQIEHISSLIK	PSMD11	341	O00231
NTTVILTAFKPHDLR	ST3GAL6	181	Q9Y274
QLFQTFTVHRSPVTK	SHKBP1	421	Q8TBC3
VTVNPSIITERFHKL	ST8SIA5	211	O15466
HPQDFKTLFETIERS	TFB2M	366	Q9H5Q4
SEPVHILKRSFARTV	MYCBP2	1401	O75592
VAKFSSVFLRLEHLQ	PRAMEF1	256	O95521
HRALPLFVITVAAIF	SLC28A3	126	Q9HAS3
KRIFETVNSVRHPFL	PKN2	706	Q16513
TFHIPVSKIVSTLLF	SLC10A5	266	Q5PT55
DIFHRLGPLSVFSAK	RHPN1	491	Q8TCX5
HPTLTFNEDFKIFLT	SNX7	131	Q9UNH6
FPTNKEFHFILDVSV	TLR1	196	Q15399
HRTSLVKQIEFNFPS	ST18	466	O60284
KSRVLHALFLFQEPR	TASOR	486	Q9UK61
KAFVILASQFLSHDP	ACSM2B	506	Q68CK6
VKAFIVLTPQFLSHD	ACSM1	511	Q08AH1
RPVAHAFVLEFLATF	AQP11	41	Q8NBQ7
SHTPVSKFVLDRIFV	CHST10	101	O43529
SQFTIFPHLVKELNA	CLRN2	81	A0PK11
FPILQATFIFSDHIR	CLEC16A	786	Q2KHT3
RNFVFHTLSPVKAEA	CLSPN	1281	Q9HAW4
IFAQFQHSREKALPS	USP53	81	Q70EK8
FHLSTTDRVIKAVPF	PPP3CC	6	P48454
VTLVKDFHVDTILFP	VNN2	221	O95498
PTDVVKVRFQASIHL	UCP3	136	P55916
DSRTLLVHKVFPGFS	SMAD7	351	O15105
AEVIKNRFHRVFLPS	USP19	731	O94966
SPFTKVERTFVHIAE	TTBK1	921	Q5TCY1
GKVFIFPSALRTHER	ZNF791	446	Q3KP31
PETVQRLNAVLKFHT	UNC80	1636	Q8N2C7
EFHPKATRTLFIGNL	SPEN	431	Q96T58
KVFVFPRESVTDHVN	APCS	26	P02743
RFTHNIRVIEPLFVF	SLC9A2	301	Q9UBY0
ASTVRRHPDKTALIF	SLC27A4	81	Q6P1M0
VAALALLFAVHSFRP	SMC1B	1131	Q8NDV3
FQAHKAILAARSPVF	SPOP	211	O43791
HSSREKIVIPFFSLL	RASGEF1C	356	Q8N431
ALRFRSTTIIFPKHA	RFLNA	161	Q6ZTI6
LAAHTTFLEQPKSFR	TP53INP1	176	Q96A56
FTPLHEAASKNRVEV	TNKS	436	O95271
LEAFSHFTKIITPAI	THRB	266	P10828
VPIHFITQSFNRKDS	TCTN1	486	Q2MV58
PFVGVLSSHFKVFRV	USP47	1071	Q96K76
FLEYQQLTHKSPIER	WDFY4	51	Q6ZS81
FQLTFLNHDVVKISP	ZDBF2	2146	Q9HCK1
VSVQRAFVHPKFSTV	PRSS42P	146	Q7Z5A4
AFVHPKFSTVTTIRN	PRSS42P	151	Q7Z5A4
LSHNRITFLKPGVFE	RXFP1	181	Q9HBX9
FEFEAHRPFVKTTRL	SCN3B	126	Q9NY72
RFTSHIRVIEPLFVF	SLC9A1	321	P19634
FEVISHSFVRKLAPN	SNX27	321	Q96L92
QSTLFRADHPFLFVI	SERPINB7	351	O75635
TFPNSHRFQLVISKA	SPATA7	206	Q9P0W8
IIIFHLKRFDIQGTT	USP50	266	Q70EL3
LRSPLQIKNHFSIAF	VPS13C	2541	Q709C8
KFLASEQHSLPVFTV	ROS1	991	P08922
TILTHVPVKEFNFRA	POLR3B	316	Q9NW08
EQFVVKAFRLFHRIP	ELAC1	171	Q9H777
RVHRKTLNPLFDETF	SYT10	286	Q6XYQ8
VTFRKILSHFPEELS	TAMM41	11	Q96BW9
VVTDFAKFSRPAQLH	UBA1	316	P22314
EASPRLRVHKTFKFV	TNFRSF10A	81	O00220
FKAIQAFVPEIFHRI	TOP3A	256	Q13472
QLFSTLPVRHKEFQR	PMS2	161	P54278
SFFQSAHLIVPEKIR	ZNF333	346	Q96JL9
QKAFHLVISPVRTED	TRDV3	91	A0JD37
LVELSAKQVAFHIPF	ZSWIM8	76	A7E2V4
PATLAVRRVKFFGQH	WDR38	6	Q5JTN6
LVDPHFAQVFLSKFT	VPS13B	3996	Q7Z7G8
AFQHSSQSIPRFIKE	SLC30A5	391	Q8TAD4
KAVILSHFFRHPNIT	STRADB	106	Q9C0K7
LKQTELFAHFIQPAA	SMARCA5	96	O60264
NHEKVVRPALIYSLF	TTLL4	566	Q14679
HLDSKTFPAETIRFL	TG	1411	P01266
ETTKRHLFFTVPRVV	TRRAP	3561	Q9Y4A5
SQRFKAHPDQLVLIF	UBQLN3	51	Q9H347
ARISFAKEPHVEQIT	THAP4	526	Q8WY91
VDLRPQSSAKVEVHF	TBCEL	336	Q5QJ74
LVFNEVFRIPVHSSA	WWC3	666	Q9ULE0
QESVKAFRPSAHLIQ	ZNF850	256	A8MQ14
SKFFLSHLVLAVPLR	PLPP7	201	Q8NBV4
ITLANKHTFDRPVEI	VWA5B1	261	Q5TIE3
NLFELARQHKPSIIF	VPS4A	211	Q9UN37
SVFKRTSPFLTHQVF	GLDC	511	P23378
IARITAKEFSPSFQH	JPH3	411	Q8WXH2
ITQHPFFKRTIALLV	NALCN	1206	Q8IZF0
LKTHPTLLENLVFFV	NAA25	831	Q14CX7
TVFIIFSRIDLFHPI	NDC1	41	Q9BTX1
SRKIHFSTAPIQVFS	PPP1R9B	446	Q96SB3
FRALVTNKPVVSALH	GRIN2B	1421	Q13224
SPTDVHRQFAIVFKT	NFKB1	301	P19838
AFRHVKVDTLSQPEA	NECAB2	356	Q7Z6G3