Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
HumanPhenoAbnormality of humoral immunity

IL12RB1 ITCH B2M CFB EPG5 DRG1 JAK3 PACS1 LIG4 NAE1 PRKCD C5 IL2RB KDM6A

1.65e-053505614HP:0005368
HumanPhenoAbnormal B cell morphology

IL12RB1 ITCH B2M CFB EPG5 DRG1 JAK3 PACS1 LIG4 NAE1 PRKCD C5 IL2RB KDM6A

2.82e-053675614HP:0002846
HumanPhenoAbnormal cellular immune system morphology

CYBB IL12RB1 ITCH B2M NSD1 CBL CFB EPG5 DRG1 JAK3 SLC17A5 PACS1 NBAS LIG4 NF1 NAE1 PRKCD C5 IL2RB KDM6A VPS13B

3.39e-057745621HP:0010987
HumanPhenoAbnormal leukocyte morphology

CYBB IL12RB1 ITCH B2M NSD1 CBL CFB EPG5 DRG1 JAK3 SLC17A5 PACS1 NBAS LIG4 NF1 NAE1 PRKCD C5 IL2RB KDM6A VPS13B

3.39e-057745621HP:0001881
HumanPhenoAbnormal immune system morphology

CYBB IL12RB1 ITCH B2M NSD1 CBL CFB EPG5 DRG1 JAK3 SLC17A5 PACS1 NBAS LIG4 NF1 NAE1 PRKCD C5 IL2RB KDM6A VPS13B

5.41e-057985621HP:0032251
DomainSHR-BD

VPS13C VPS13D VPS13B

2.36e-0641583IPR009543
DomainVPS13_C

VPS13C VPS13D VPS13B

2.36e-0641583PF16909
DomainVPS13_C

VPS13C VPS13D VPS13B

2.36e-0641583IPR031645
DomainSHR-BD

VPS13C VPS13D VPS13B

2.36e-0641583PF06650
DomainChorein_N

VPS13C VPS13D VPS13B

3.22e-0581583PF12624
DomainVPS13_N

VPS13C VPS13D VPS13B

3.22e-0581583IPR026854
DomainFrizzled

FZD7 FZD8 FZD5

9.32e-05111583IPR000539
DomainFrizzled

FZD7 FZD8 FZD5

9.32e-05111583PF01534
DomainFrizzled

FZD7 FZD8 FZD5

9.32e-05111583SM01330
DomainCRAL_TRIO_2

PRUNE2 NF1 ARHGAP8

1.24e-04121583PF13716
DomainVPS13

VPS13C VPS13D

2.12e-0431582IPR026847
DomainVPS13_mid_rpt

VPS13C VPS13D

2.12e-0431582PF16910
DomainVPS13

VPS13C VPS13D

2.12e-0431582PF16908
DomainVPS13_N2

VPS13C VPS13D

2.12e-0431582IPR031646
DomainVPS13_mid_rpt

VPS13C VPS13D

2.12e-0431582IPR031642
DomainFrizzled/SFRP

FZD7 FZD8 FZD5

3.07e-04161583IPR015526
DomainFRI

FZD7 FZD8 FZD5

6.09e-04201583SM00063
DomainAutophagy-rel_C

VPS13C VPS13B

6.99e-0451582IPR015412
DomainATG_C

VPS13C VPS13B

6.99e-0451582PF09333
Domain-

FZD7 FZD8 FZD5

7.06e-042115831.10.2000.10
DomainQuinoprotein_ADH-like_supfam

NWD1 ERN1 AHCTF1 WDR72

1.05e-03531584IPR011047
DomainFrizzled_dom

FZD7 FZD8 FZD5

1.06e-03241583IPR020067
DomainFZ

FZD7 FZD8 FZD5

1.06e-03241583PS50038
DomainFz

FZD7 FZD8 FZD5

1.06e-03241583PF01392
Pubmed

Analysis of the human VPS13 gene family.

VPS13C VPS13D VPS13B

4.33e-074167315498460
Pubmed

Autosomal dominant familial exudative vitreoretinopathy in two Japanese families with FZD4 mutations (H69Y and C181R).

FZD7 FZD8 FZD5

3.75e-067167315370539
Pubmed

Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action.

FZD7 FZD8 FZD5

3.75e-06716739192640
Pubmed

MAGI-3 is involved in the regulation of the JNK signaling pathway as a scaffold protein for frizzled and Ltap.

FZD7 FZD8 FZD5

3.75e-067167315195140
Pubmed

Wnt signaling is required for thymocyte development and activates Tcf-1 mediated transcription.

FZD7 FZD8 FZD5

3.75e-067167311265645
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

IPO7 AHCTF1 CEBPZ UBTF OSBPL8 ASCC3 ZNF512 DDX28 TOP2B SEC13

5.17e-063321671025693804
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NWD1 MYO7A TSC1 PRPF6 VPS13D TRANK1 UBTF OSBPL8 UBA6 GALNT5 RMND1 ASCC3

5.64e-064971671236774506
Pubmed

Differential expression of the Wnt putative receptors Frizzled during mouse somitogenesis.

FZD7 FZD8 FZD5

5.98e-068167310559494
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ACTR8 ITCH TMEM165 CECR2 AHCTF1 L1TD1 FBXL6 DRG1 PPP2R5A MCTP1 UTP25 PCSK6 LTN1 OSMR ASCC3 TENT2 ARAP2 WDR72

7.78e-0611161671831753913
Pubmed

Identification of quantitative trait loci controlling cortical motor evoked potentials in experimental autoimmune encephalomyelitis: correlation with incidence, onset and severity of disease.

CPE JAK3 C5

8.94e-069167315917267
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KBTBD3 PRUNE2 ATRN MBTPS1 UBE2K ITCH VPS13C SLC22A23 NAIP CASZ1 PLEKHG4B PACS1 SGSM2 NGEF KCNMA1 UBA6 NLGN2 ZNF512 ARHGAP8 KDM6A VPS13B

1.02e-0514891672128611215
Pubmed

Identification of synthetic lethality of PRKDC in MYC-dependent human cancers by pooled shRNA screening.

ERN1 PRKCD PSKH2

1.27e-0510167325495526
Pubmed

Expression of Frizzled genes in developing and postnatal hair follicles.

FZD7 FZD8 FZD5

1.27e-0510167315245425
Pubmed

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.

FZD7 FZD8 FZD5

1.27e-0510167317532316
Pubmed

Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.

FZD7 FZD8 FZD5

1.74e-0511167324860427
Pubmed

Molecular determinants of WNT9b responsiveness in nephron progenitor cells.

FZD7 FZD8 FZD5

1.74e-0511167330978219
Pubmed

Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.

FZD7 FZD8 FZD5

1.74e-0511167317576136
Pubmed

Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.

FZD7 FZD8 FZD5

1.74e-0511167317582687
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

IPO7 AHCTF1 NSD1 PRPF6 NF1 UTP25 CEBPZ UBTF OSBPL8 ASCC3 ZNF512 SF3B2 SEC13

1.79e-056531671322586326
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

IPO7 DPY19L1 CECR2 AHCTF1 L1TD1 CEBPZ UBTF MTFR2 ASCC3 KDM6A TOP2B

1.83e-054691671127634302
Pubmed

The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation.

MBTPS1 C5

2.29e-052167225000985
Pubmed

Coinheritance of Novel Mutations in SCN1A Causing GEFS+ and in KDM6A Causing Kabuki Syndrome in a Family.

SCN1A KDM6A

2.29e-052167228442529
Pubmed

Coupling of 6-phosphogluconate dehydrogenase with NADPH oxidase in neutrophils: Nox2 activity regulation by NADPH availability.

CYBB PGD

2.29e-052167221444627
Pubmed

Yip1A, a novel host factor for the activation of the IRE1 pathway of the unfolded protein response during Brucella infection.

ERN1 YIPF5

2.29e-052167225742138
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MBTPS1 PPRC1 TSC1 EPG5 UNC5A SGSM2 OGFOD1 MARCHF4 VPS13B ARAP2

2.99e-054071671012693553
Pubmed

Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos.

FZD7 FZD8 FZD5

3.00e-0513167322266179
Pubmed

Pigmentation-related genes and their implication in malignant melanoma susceptibility.

ATRN MYO7A VPS13B

3.81e-0514167319320733
Pubmed

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

DRD1 CAMK4 CYP17A1 PCLO RUNX3 CCND2 KCNMA1

4.35e-05193167720677014
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

ITCH IPO7 TMEM165 AHCTF1 B2M SLC35E1 PTGFRN DRG1 LMF2 SCAP CEBPZ PCSK6 OSBPL8 ASCC3 IQGAP3

5.33e-059421671531073040
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

MARS2 IPO7 VPS13C PCLO PRPF6 PGD TFCP2 DRG1 NF1 CEBPZ UBTF UBA6 PRKCD PRMT3 GALNT5 ZNF512 IQGAP3 SF3B2 TOP2B

5.90e-0514251671930948266
Pubmed

Regulation of immune responses by E3 ubiquitin-protein ligases.

ITCH CBL

6.85e-053167211826757
Pubmed

The Balpha and Bdelta regulatory subunits of PP2A are necessary for assembly of the CaMKIV.PP2A signaling complex.

CAMK4 PPP2R5A

6.85e-053167219538941
Pubmed

Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells.

JAK3 IL2RB

6.85e-053167221345943
Pubmed

Identification of a PDZ domain containing Golgi protein, GOPC, as an interaction partner of frizzled.

FZD8 FZD5

6.85e-053167211520064
Pubmed

Frizzled7 functions as a Wnt receptor in intestinal epithelial Lgr5(+) stem cells.

FZD7 FZD5

6.85e-053167225892522
Pubmed

Overexpression of the Runx3 transcription factor increases the proportion of mature thymocytes of the CD8 single-positive lineage.

B2M RUNX3

6.85e-053167215728469
Pubmed

Interleukin-2 receptor beta (IL-2R beta)-627*C homozygote but not IL-12R beta 1 codon 378 or IL-18 105 polymorphism is associated with higher susceptibility to endometriosis.

IL12RB1 IL2RB

6.85e-053167216084898
Pubmed

Protein kinase C delta activates topoisomerase IIalpha to induce apoptotic cell death in response to DNA damage.

PRKCD TOP2B

6.85e-053167216611985
Pubmed

Single nucleotide polymorphisms of the genes IL-2, IL-2RB, and JAK3 in patients with cutaneous leishmaniasis caused by Leishmania (V.) guyanensis in Manaus, Amazonas, Brazil.

JAK3 IL2RB

6.85e-053167231393896
Pubmed

Expression of the complement system's activation factors in plasma of patients with early/late-onset severe pre-eclampsia.

CFB C5

6.85e-053167227461873
Pubmed

Alterations in gene expression of complement components in chronic rhinosinusitis.

CFB C5

6.85e-053167220109314
Pubmed

Neurofibromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans.

CYBB NF1

6.85e-053167227266634
Pubmed

Neddylation stabilizes Nav1.1 to maintain interneuron excitability and prevent seizures in murine epilepsy models.

SCN1A NAE1

6.85e-053167233651714
Pubmed

Protein kinase C-δ mediates sepsis-induced activation of complement 5a and urokinase-type plasminogen activator signaling in macrophages.

PRKCD C5

6.85e-053167224682410
Pubmed

Interaction between two ubiquitin-protein isopeptide ligases of different classes, CBLC and AIP4/ITCH.

ITCH CBL

6.85e-053167212226085
Pubmed

Loss of the Wnt receptor frizzled 7 in the mouse gastric epithelium is deleterious and triggers rapid repopulation in vivo.

FZD7 FZD5

6.85e-053167228600348
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

IL12RB1 CCKAR CMA1 KCNMA1 OSMR IL2RB

6.95e-05143167620424473
Pubmed

Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting of receptor gene families.

FZD7 FZD8 FZD5

7.04e-0517167328733458
Pubmed

HERC5/IFI16/p53 signaling mediates breast cancer cell proliferation and migration.

UBE2K B2M CBL NAE1 UBA6

7.60e-0590167535671810
Pubmed

Wilms Tumor Predisposition

DIS3L2 NSD1 NF1

8.41e-0518167320301471
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

STRN3 UBE2K REXO5 IPO7 VPS13C PGD VPS13D LTN1 KCNMA1 IQGAP3 DDX28

9.60e-055641671121565611
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

ITCH CBL LTN1 UBA6 HERC6

9.83e-0595167529643511
Pubmed

Regulation of angiogenesis by a non-canonical Wnt-Flt1 pathway in myeloid cells.

FZD7 FZD8 FZD5

9.96e-0519167321623369
Pubmed

Biological insights from 108 schizophrenia-associated genetic loci.

MARS2 CYP17A1 ITIH3 TRANK1 SGSM2 NGEF C12orf42 DDX28

1.16e-04303167825056061
Pubmed

The IL-2 receptor beta chain gene (Il-2rb) is closely linked to the Pdgfb locus on mouse chromosome 15.

B2M ALDH4A1 C5 IL2RB

1.34e-045416748482578
Pubmed

RUNX represses Pmp22 to drive neurofibromagenesis.

RUNX3 NF1

1.37e-044167231032403
Pubmed

SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells.

CBL MS4A2

1.37e-04416728995445
Pubmed

Distinct C-mannosylation of netrin receptor thrombospondin type 1 repeats by mammalian DPY19L1 and DPY19L3.

DPY19L1 UNC5A

1.37e-044167228202721
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

NF1 SCN1A

1.37e-044167222260870
Pubmed

Mutations in OTOGL, encoding the inner ear protein otogelin-like, cause moderate sensorineural hearing loss.

MYO7A OTOGL

1.37e-044167223122586
Pubmed

Complement C3b interactions studied with surface plasmon resonance technique.

CFB C5

1.37e-044167211367533
Pubmed

The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.

B2M RUNX3

1.37e-044167217646406
Pubmed

Mobilization studies in complement-deficient mice reveal that optimal AMD3100 mobilization of hematopoietic stem cells depends on complement cascade activation by AMD3100-stimulated granulocytes.

CFB C5

1.37e-044167220033053
Pubmed

Recruitment of SH2-containing protein tyrosine phosphatase SHP-1 to the interleukin 2 receptor; loss of SHP-1 expression in human T-lymphotropic virus type I-transformed T cells.

JAK3 IL2RB

1.37e-04416729520455
Pubmed

Characterization and expression of the complementary DNA encoding rat histidine decarboxylase.

B2M C5

1.37e-04416722300558
Pubmed

Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the gamma chain.

JAK3 IL2RB

1.37e-044167218829468
Pubmed

In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome.

TSC1 NF1

1.37e-044167226190969
Pubmed

Properdin provides protection from Citrobacter rodentium-induced intestinal inflammation in a C5a/IL-6-dependent manner.

CFB C5

1.37e-044167225725105
Pubmed

Lineage fate alteration of thymocytes developing in an MHC environment containing MHC/peptide ligands with antagonist properties.

B2M C5

1.37e-044167211745379
Pubmed

Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma.

TSC1 NF1

1.37e-044167216267007
Pubmed

Delineation of the regions of interleukin-2 (IL-2) receptor beta chain important for association of Jak1 and Jak3. Jak1-independent functional recruitment of Jak3 to Il-2Rbeta.

JAK3 IL2RB

1.37e-04416729553136
Pubmed

JAB/SOCS1/SSI-1 is an interleukin-2-induced inhibitor of IL-2 signaling.

JAK3 IL2RB

1.37e-044167211133764
Pubmed

SOCS-3 is tyrosine phosphorylated in response to interleukin-2 and suppresses STAT5 phosphorylation and lymphocyte proliferation.

JAK3 IL2RB

1.37e-044167210373548
Pubmed

Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits.

JAK3 IL2RB

1.37e-04416727973659
Pubmed

Interaction of IL-2R beta and gamma c chains with Jak1 and Jak3: implications for XSCID and XCID.

JAK3 IL2RB

1.37e-04416727973658
Pubmed

Dopamine synapse is a neuroligin-2-mediated contact between dopaminergic presynaptic and GABAergic postsynaptic structures.

DRD1 NLGN2

1.37e-044167227035941
Pubmed

Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in TgE26 mice.

B2M IL2RB

1.37e-04416729002646
Pubmed

Reciprocal regulation of the ubiquitin ligase Itch and the epidermal growth factor receptor signaling.

ITCH CBL

1.37e-044167219341794
Pubmed

Analysis of SNP profiles in patients with major depressive disorder.

DRD1 CCKAR

1.37e-044167215927089
Pubmed

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.

ITIH3 PACS1 TRANK1 PRKCD SF3B2

1.38e-04102167521926972
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PRUNE2 PTGFRN CASZ1 VPS13D SCAP DNAH17 LTN1 OSBPL8 NLGN2 ZNF512

1.46e-044931671015368895
Pubmed

Expression of the Wnt inhibitor Dickkopf-1 is required for the induction of neural markers in mouse embryonic stem cells differentiating in response to retinoic acid.

FZD7 FZD8 FZD5

1.57e-0422167317064353
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

ATRN PPRC1 PCLO VPS13B ARAP2

1.58e-0410516759628581
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

MBTPS1 KLHL10 EFCAB6 PRPF6 ARMCX5 NDUFB6 ECHDC3 SLC17A5 YIPF5 PPP2R5A NF1 UBTF ZNF92 ZNF85 OSMR ZNF512 RIMS2

1.74e-0412931671715342556
Pubmed

Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes.

PRPF6 SF3B2 SEC13

1.79e-0423167320696395
Pubmed

Gene network and familial analyses uncover a gene network involving Tbx5/Osr1/Pcsk6 interaction in the second heart field for atrial septation.

CCND2 FZD7 PCSK6

2.04e-0424167326744331
Pubmed

Adult-onset Alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model.

IL12RB1 JAK3 IL2RB

2.04e-0424167315245428
Pubmed

A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors.

FZD7 FZD8 FZD5

2.04e-042416739096311
Pubmed

A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled.

FZD7 FZD8 FZD5

2.04e-042416738626800
Pubmed

Sphingosylphosphorylcholine potentiates vasoreactivity and voltage-gated Ca2+ entry via NOX1 and reactive oxygen species.

CYBB PRKCD

2.27e-045167225661082
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A C5

2.27e-04516721679748
Pubmed

Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.

JAK3 IL2RB

2.27e-045167223341462
Pubmed

Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis.

PCLO RIMS2

2.27e-045167212401793
Pubmed

Molecular basis for differential modulation of BK channel voltage-dependent gating by auxiliary γ subunits.

LRRC38 KCNMA1

2.27e-045167226009545
Pubmed

BK potassium channel modulation by leucine-rich repeat-containing proteins.

LRRC38 KCNMA1

2.27e-045167222547800
Pubmed

Evidence for a major cluster of lymphocyte differentiation antigens on murine chromosome 2.

B2M C5

2.27e-04516726961423
Pubmed

Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.

FZD7 FZD5

2.27e-045167230622113
Pubmed

Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins.

B2M CBL

2.27e-045167217045823
Pubmed

Alternative complement pathway in the pathogenesis of disease mediated by anti-neutrophil cytoplasmic autoantibodies.

CFB C5

2.27e-045167217200182
Pubmed

Gene for a major cell surface glycoprotein of mouse macrophages and other phagocytic cells is on chromosome 2.

B2M C5

2.27e-04516726952244
GeneFamilyG protein-coupled receptors, Class F frizzled

FZD7 FZD8 FZD5

3.12e-05111063286
GeneFamilyRho GTPase activating proteins|BCH domain containing

PRUNE2 ARHGAP8

7.01e-04710621299
GeneFamilyProprotein convertase subtilisin/kexin family

MBTPS1 PCSK6

1.19e-0391062973
GeneFamilyUbiquitin like modifier activating enzymes

NAE1 UBA6

1.49e-03101062100
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IPO7 VPS13C NSD1 CPE PRPF6 ASCC3 KDM6A TOP2B

3.33e-071761668749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK4 NSD1 RUNX3 CCND2 LY75 IL2RB TOP2B ARAP2

4.30e-071821668e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Marrow-nan-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK4 NSD1 RUNX3 CCND2 LY75 IL2RB TOP2B ARAP2

4.30e-0718216681710eab3037a87609d21838be2d2d29c3bc36651
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL12RB1 REXO5 B2M RUNX3 CCND2 RMND1 IL2RB

3.99e-06173166742272af45547422ef85e35f4a4c7d269e9ed7a8a
ToppCellLV-17._Lymphocyte|World / Chamber and Cluster_Paper

ERN1 CAMK4 B2M RUNX3 MS4A2 CMA1 ARAP2

3.99e-061731667212f013ff761cbab24a537071739867c08c402a4
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL12RB1 REXO5 B2M RUNX3 CCND2 RMND1 IL2RB

4.15e-0617416675c69447261c5aa309a24882656da90655728d637
ToppCell-Hematopoietic_Mast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAOX MCTP1 MS4A2 CMA1

5.93e-06321664ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell-Hematopoietic_Mast-Mast_cells-Mast-cells| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAOX MCTP1 MS4A2 CMA1

5.93e-06321664c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell-Hematopoietic_Mast-Mast_cells| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAOX MCTP1 MS4A2 CMA1

5.93e-06321664de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCellfacs-Thymus-nan-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK4 VPS13C SPO11 CBL LIG4 PPP2R5A TOP2B

8.18e-061931667a6a864644e1b80b7417ea0a27281e79068a3fd3d
ToppCellfacs-Aorta-Heart-3m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 NWD1 CHRNB3 MS4A2 TSPO2 SCN1A

1.38e-05139166622a769d5195ed761ef333ef542746e1ba617a698
ToppCellfacs-Aorta-Heart-3m-Myeloid-professional_antigen_presenting_cell|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 NWD1 CHRNB3 MS4A2 TSPO2 SCN1A

1.38e-051391666292533e04178dd36d57377562077f9deb2cb9746
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Trm/em_CD8|GI_large-bowel / Manually curated celltypes from each tissue

MYLK COQ3 ZNF585B NLGN2 ARHGAP8 ARAP2

2.75e-051571666d85304af4cd3b8aaedc5362a8223537e1b9dbec2
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB NPTX2 LRRC43 MCTP1 SCN1A PRKCD

2.85e-051581666bd37d567754b660bfff7aef81cb307a384ec20a0
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-ILC3|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

IL12RB1 EFCAB6 ERN1 LRRC38 MYO7A RUNX3

3.16e-051611666584e44e6048c2678eb72cd23a86f48f2466c5da4
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-7|TCGA-Thryoid / Sample_Type by Project: Shred V9

DRD1 CYP17A1 SLC22A23 PGD ALDH4A1 GABRR3

3.88e-05167166601c42e555913b17e62846325cc17b3d8f92da1e1
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NWD1 LRRC38 INSRR CPE NEMP2 TSPO2

3.88e-051671666b94e8ee8c3fcebedd8fcd719eadddc04c7513c50
ToppCelldroplet-Lung-nan-21m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 B2M RUNX3 CCND2 RMND1 IL2RB

4.15e-05169166618ba8fc2ba8838484d3b223428cd41568e2ccb10
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KBTBD3 B2M PLEKHG4B FZD8 UTP25 ARAP2

4.15e-051691666665b958f4a720ca369a8a0abc7fbe8b6e13c8ce5
ToppCelldroplet-Lung-nan-21m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 B2M RUNX3 CCND2 RMND1 IL2RB

4.15e-05169166647a63afd80cb7ba2258ba57d3084d8b2a7bc4e8d
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

KBTBD3 B2M PLEKHG4B FZD8 UTP25 ARAP2

4.15e-0516916666614c9851537e4c21b1e45ff0cc3bad07ef9d034
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 DPY19L1 PTGFRN OTOGL C12orf42 ABCC12

4.43e-0517116666a489a75eeab2a2d48d604682e93599c20a945fe
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL12RB1 RUNX3 NXPE3 CCND2 VPS13D LY75

4.73e-05173166615a77f6aac968b7a1afea4f60aedbb95b9d0f765
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-L_cells_(PYY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPTX2 PCLO CPE RIMS2 MARCHF4 PSKH2

4.73e-0517316669a3500b06d00d1d4ee42910a3a73327b21beab52
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCLO CPE RXFP4 RIMS2 MARCHF4 PSKH2

4.88e-0517416669f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 B2M RUNX3 CCND2 IL2RB ARAP2

5.20e-051761666e2b4be7d4f31a78d7862c0fd629dd9cc84589193
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 B2M RUNX3 CCND2 IL2RB ARAP2

5.20e-051761666299075e65ca86564e1c0b06058bd4371a60a3bcd
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C B2M NSD1 ASCC3 HERC6 ARAP2

5.54e-05178166601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

CAMK4 B2M RUNX3 JAK3 MCTP1 MS4A2

5.54e-05178166634ec499d03cc198cfefa19a724d4c81974052f65
ToppCelldroplet-Marrow-nan-3m-Hematologic-hematopoietic_precursor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CAMK4 RUNX3 CCND2 IL2RB TOP2B ARAP2

5.54e-0517816668aef208b6351143562c87715bb11628880abce94
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 MYLK CASZ1 FZD7 AOC3 KCNMA1

5.71e-051791666e860dca9b28ac5af61804bfd729cd39257cdb352
ToppCellfacs-SCAT-Fat-3m-Lymphocytic-NK_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 CAMK4 RUNX3 CCND2 C12orf42 IL2RB

5.71e-0517916666f657c7a227f860934d0dfec9b97d35fd2cedfd2
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

PRUNE2 MYLK CPE ITIH3 AOC3 KCNMA1

5.71e-051791666a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|Fibroblasts / Location, Cell class and cell subclass

PRUNE2 MBTPS1 DIS3L2 THSD7B FZD7 UTP25

5.71e-05179166683506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 PCLO CPE RXFP4 NLGN2 MARCHF4

5.89e-0518016669db9899ca42455310e9b63df523fe6c4780abfb7
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Thalamus / BrainAtlas - Mouse McCarroll V32

CYBB RUNX3 MS4A2 CMA1 ANGPTL7

6.02e-051111665a1b7940c6fa0e5a58aa4798b604469d79f33fa44
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Thalamus / BrainAtlas - Mouse McCarroll V32

CYBB RUNX3 MS4A2 CMA1 ANGPTL7

6.02e-051111665d1ec8e8e9adb11511b4ef363cc6f99286e2cc842
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Thalamus / BrainAtlas - Mouse McCarroll V32

CYBB RUNX3 MS4A2 CMA1 ANGPTL7

6.02e-051111665567e5ac2c78d45db207067f0f152bb24ed048c50
ToppCellThalamus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Thalamus / BrainAtlas - Mouse McCarroll V32

CYBB RUNX3 MS4A2 CMA1 ANGPTL7

6.02e-051111665fd7aa25e83a0d762969e3966a658652da40c490e
ToppCellThalamus-Hematopoietic-MACROPHAGE|Thalamus / BrainAtlas - Mouse McCarroll V32

CYBB RUNX3 MS4A2 CMA1 ANGPTL7

6.02e-051111665d48561078c387ac856c1c30e3d7a3e75ebde942e
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CAMK4 VPS13C RUNX3 CCND2 ASCC3 IL2RB

6.08e-051811666986c036e656f24fe374807e2711cec9e3c83c892
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL12RB1 B2M RUNX3 CCND2 IL2RB ARAP2

6.08e-051811666a2c03bd7adc4a65f3b373c229ec0ecc84f724b17
ToppCellCOVID-19-T_cells-Tregs|COVID-19 / group, cell type (main and fine annotations)

CAMK4 CCND2 JAK3 PACS1 LY75 IL2RB

6.08e-051811666534659cf754326c6a73c0daa30e9d610612a0292
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

ERN1 CAMK4 B2M RUNX3 MS4A2 ARAP2

6.08e-05181166681fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCellLA-17._Lymphocyte|LA / Chamber and Cluster_Paper

CAMK4 B2M RUNX3 JAK3 MCTP1 MS4A2

6.08e-0518116663fd9f805fa46141b0fa7023ee5d8688d338635d5
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-mature_NK_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IL12RB1 B2M RUNX3 CCND2 IL2RB ARAP2

6.08e-051811666c073e6c917354528ac5bad88a226e1134004ba43
ToppCellPCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NPTX2 FZD8 SCN1A PCSK6 RIMS2 ARAP2

6.08e-051811666fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PRUNE2 NPTX2 MYLK NGEF KCNMA1 RIMS2

6.46e-051831666a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C NSD1 CEBPZ ASCC3 KDM6A TOP2B

6.65e-0518416661154a5ad7b8512272b7476f949ddac350910bfb7
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL12RB1 B2M RUNX3 CCND2 IL2RB ARAP2

6.86e-051851666c9ab7a3584d25f0ed73b20919c3dba00f502eac4
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO7A PCLO ITIH3 UNC5A MCTP1 PCSK6

6.86e-0518516663be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MYO7A PCLO ITIH3 UNC5A MCTP1 PCSK6

6.86e-051851666c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DPY19L1 CAMK4 UNC5A NGEF KCNMA1 ARAP2

7.06e-05186166656c139e679d640ea901ead657a8e8887e0fca098
ToppCellFetal_29-31_weeks-Epithelial-lung_neuroendocrine_cell_(PNEC)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PRUNE2 PCLO CPE C12orf42 RIMS2 MARCHF4

7.06e-051861666b45cce768e4bf91da194fd9660cab7520dfb15ac
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

VPS13C AHCTF1 EPG5 NF1 KDM6A ARAP2

7.49e-051881666ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell21-Trachea-Epithelial-Neuroendocrine|Trachea / Age, Tissue, Lineage and Cell class

PRUNE2 PCLO CPE KCNMA1 RIMS2 MARCHF4

7.49e-051881666e78d4f7a5d28c77503cb041ff585d13df4c88bd2
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERN1 CAMK4 B2M CCND2 TRANK1 IL2RB

7.94e-05190166655df73c8b696967a925b1772631f6900eff0fa30
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRUNE2 MYLK CASZ1 PLEKHG4B AOC3 KCNMA1

7.94e-051901666e102622f05c7f3e1bd8b224ea159d57033793ee0
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ERN1 CAMK4 B2M CCND2 TRANK1 IL2RB

7.94e-051901666494fbab37305a7f92cddec75b291d42282555f5f
ToppCellCOVID-19-kidney-T-cells-2|kidney / Disease (COVID-19 only), tissue and cell type

CAMK4 B2M RUNX3 CCND2 JAK3 IL2RB

8.18e-051911666698e6a28276704f8baa082d028db2345b973c4bc
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRUNE2 SLC22A23 PCLO INSRR CPE KCNMA1

8.18e-051911666f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellNS-moderate-d_16-33-Lymphoid-Treg|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

IL12RB1 CAMK4 RUNX3 CCND2 JAK3 IL2RB

8.41e-05192166648d557071bad80edd3ec6e5ad8dcd97037da9553
ToppCellmoderate-Lymphoid-Treg|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IL12RB1 CAMK4 RUNX3 CCND2 JAK3 IL2RB

8.41e-051921666e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCellHealthy_Control-Lymphoid-T-CCR7+_T|Healthy_Control / Condition, Lineage, Cell class and cell subclass

CAMK4 RUNX3 CCND2 JAK3 C12orf42 IL2RB

8.41e-0519216665b197f65a87c315e4f50c77a7fdec3b342a863ad
ToppCellT_cell|World / shred by cell class for nasal brushing

CAMK4 B2M RUNX3 CCND2 JAK3 IL2RB

8.66e-05193166607530bbeffd5951880ed6ea50a962c102b05ccc2
ToppCellCOVID-19-kidney-T-cells-1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CAMK4 RUNX3 JAK3 C12orf42 IL2RB ARAP2

8.66e-0519316665b84fa640cf30dea55fde53b810f850ff946d253
ToppCellfacs-Thymus-nan-3m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 CAMK4 CBL LIG4 PPP2R5A TOP2B

8.91e-051941666f1661f9f2439fca5c1012c693b0744c4e3b90a9b
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells-NK_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERN1 B2M RUNX3 LRRC43 IL2RB ARAP2

8.91e-0519416663fe32e38c95135d152acb1624fec1623339e144a
ToppCellfacs-Thymus-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 CAMK4 CBL LIG4 PPP2R5A TOP2B

8.91e-051941666cda1b197efb199330ea7ab25a7cee22cae22589d
ToppCellfacs-Thymus-nan-3m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 CAMK4 CBL LIG4 PPP2R5A TOP2B

8.91e-05194166666c056232ac216780acf4cc8ea325bd8ed1909c9
ToppCellhuman_hepatoblastoma-NK.T_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

IL12RB1 CAMK4 RUNX3 JAK3 IL2RB ARAP2

8.91e-051941666997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERN1 CAMK4 B2M RUNX3 TRANK1 IL2RB

9.16e-051951666662b50a2aa97373bf343b88caace9717049c722a
ToppCellfacs-Thymus-nan-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTPS1 CAMK4 CBL LIG4 PPP2R5A TOP2B

9.16e-05195166679114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

CAMK4 B2M RUNX3 CCND2 JAK3 IL2RB

9.16e-05195166636c784709ee32174e05b457500339c3b8eee3244
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ERN1 CAMK4 B2M RUNX3 TRANK1 IL2RB

9.16e-0519516669b7157b5e4b81bc35b0e6d9b954279160ea57324
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VPS13C PCLO INSRR NSD1 CPE ASCC3

9.16e-0519516663e519cffa6144a62b06124642a14c9ff39b76554
ToppCellMild|World / Disease group and Cell class

RUNX3 TRANK1 HERC6 IL2RB KDM6A ARAP2

9.42e-0519616665e4ed4a5a437cfa002b92775992a791e27aa4c27
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-T_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERN1 CAMK4 B2M RUNX3 IL2RB ARAP2

9.69e-05197166607475c0785534ba845acec0e33310d57ad7352e6
ToppCell5'-Airway_Nasal-Immune_Lymphocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAMK4 B2M RUNX3 CCND2 JAK3 IL2RB

9.69e-05197166640b752b019c95994323c7f65644a6ccf336d327e
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAMK4 RUNX3 CCND2 TRANK1 IL2RB ARAP2

9.69e-051971666927bf36bad3bcb7346c13b660777c1c0de7dc322
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-CD8+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CAMK4 RUNX3 CCND2 TRANK1 IL2RB ARAP2

9.69e-0519716663e09158507df08c08e08613ce23617206280c911
ToppCell5'-Airway_Nasal-Immune_Lymphocytic-Lymphocytic_T/NK|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CAMK4 B2M RUNX3 CCND2 JAK3 IL2RB

9.69e-051971666486af69d2840d351790ee41dc7438c02c615740b
ToppCellmild_COVID-19_(asymptomatic)-NK|World / disease group, cell group and cell class (v2)

B2M RUNX3 EPG5 CCND2 IL2RB ARAP2

9.96e-0519816667a0aac52d785037455e068e1b25de4b2bf0fff79
ToppCellCOVID-19-Lymphoid-CD8_T_cells|COVID-19 / Condition, Lineage and Cell class

CAMK4 B2M RUNX3 CCND2 IL2RB ARAP2

1.02e-0419916668e322d0d097df160554e3024ec9edae4a77a66cc
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

PACS1 NBAS NF1 KCNMA1 KDM6A VPS13B

1.02e-04199166694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

VPS13C SLC22A23 CECR2 ALDH4A1 C5 GALNT5

1.05e-0420016662dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellCOVID-19-Lymphoid|COVID-19 / Condition, Lineage and Cell class

ERN1 CAMK4 B2M RUNX3 CCND2 IL2RB

1.05e-0420016664408304fd43c6e329b0d7e131f1759e7f2932299
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

RUNX3 CCND2 TRANK1 HERC6 IL2RB ARAP2

1.05e-0420016662281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP17A1 RUNX3 CCND2 CMA1 IL2RB

1.80e-041401665568a008ff103269e9fe36aa95e9d302641efed98
DrugAmpyrone [83-07-8]; Up 200; 19.6uM; MCF7; HT_HG-U133A

DRD1 ERN1 CAMK4 PACS1 NF1 MCTP1 PCSK6 KCNMA1 HERC6 DDX28

1.64e-06197163102249_UP
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

CBL JAK3 NF1

4.90e-0671553DOID:0050458 (is_implicated_in)
Diseaseautosomal recessive spinocerebellar ataxia 4 (implicated_via_orthology)

VPS13C VPS13D

8.20e-0531552DOID:0111611 (implicated_via_orthology)
DiseaseCohen syndrome (implicated_via_orthology)

VPS13C VPS13B

8.20e-0531552DOID:0111590 (implicated_via_orthology)
DiseaseJuvenile Myelomonocytic Leukemia

CBL JAK3 NF1

1.30e-04191553C0349639
DiseaseJUVENILE MYELOMONOCYTIC LEUKEMIA

CBL NF1

1.63e-0441552607785
Diseasefactor VIII deficiency (is_marker_for)

CFB C5

1.63e-0441552DOID:12134 (is_marker_for)
DiseaseJuvenile myelomonocytic leukemia

CBL NF1

1.63e-0441552cv:C0349639
DiseaseImmunologic Deficiency Syndromes

EPG5 NBAS C5

2.33e-04231553C0021051
DiseaseLupus Erythematosus, Discoid

CYBB C5

2.71e-0451552C0024138
Diseasepursuit maintenance gain measurement

NPTX2 IPO7 EPG5 NGEF PRMT3

4.92e-041231555EFO_0008433
Diseasemultiple myeloma (is_marker_for)

B2M CBL CCND2

8.94e-04361553DOID:9538 (is_marker_for)
DiseaseBipolar Disorder

GABRG1 DRD1 PCLO ITIH3 CCKAR CHRNB3 PACS1 TRANK1 IL2RB

9.82e-044771559C0005586
Disease2-aminobutyrate measurement

EPG5 C12orf42

1.20e-03101552EFO_0020017
Diseasecocaine use

CHRNB3 SCN1A

1.46e-03111552C3496069
Diseasesleep disorder (implicated_via_orthology)

INSRR NF1

1.46e-03111552DOID:535 (implicated_via_orthology)
Diseaseasthma (is_implicated_in)

MYLK MS4A2 CMA1 C5 IL2RB

1.47e-031571555DOID:2841 (is_implicated_in)
DiseaseLeukemia, Myelocytic, Acute

NSD1 RUNX3 CBL CCND2 NF1

2.25e-031731555C0023467
DiseaseLiver Cirrhosis, Experimental

CYBB PRUNE2 ATRN ERN1 CYP17A1 TMEM165 SLC22A23 FZD8 CES3 PRKCD IL2RB

2.69e-0377415511C0023893
DiseaseNeoplasm of uncertain or unknown behavior of bladder

TSC1 KDM6A

2.75e-03151552C0496930
DiseaseBenign neoplasm of bladder

TSC1 KDM6A

2.75e-03151552C0154017
DiseaseCarcinoma in situ of bladder

TSC1 KDM6A

2.75e-03151552C0154091
Diseaseglycerate measurement

THSD7B MCTP1

2.75e-03151552EFO_0021029
DiseaseRASopathy

CBL NF1

2.75e-03151552cv:C5555857
DiseaseGastro-enteropancreatic neuroendocrine tumor

RUNX3 IL2RB

2.75e-03151552C2930967
DiseaseGlioblastoma Multiforme

ERN1 INSRR RUNX3 NF1

2.84e-031111554C1621958
DiseaseAlcoholic Intoxication, Chronic

GABRG1 DRD1 THSD7B CCKAR CHRNB3 SLC17A5

3.01e-032681556C0001973
Diseaseidiopathic scoliosis (implicated_via_orthology)

MBTPS1 RUNX3

3.13e-03161552DOID:0060250 (implicated_via_orthology)
Diseasepartial epilepsy

FZD7 SCN1A

3.54e-03171552EFO_0004263
DiseaseAntibody Deficiency Syndrome

EPG5 C5

3.54e-03171552C0003257
Diseaseidiopathic dilated cardiomyopathy

MARS2 AADACL2 DNAH17

3.91e-03601553EFO_0009094
DiseaseCarcinoma of bladder

TSC1 KDM6A

3.97e-03181552C0699885
Diseaseosteoarthritis, hip, osteoarthritis, knee

BTNL8 THSD7B NF1

4.29e-03621553EFO_0004616, EFO_1000786
DiseaseAcute Myeloid Leukemia, M1

NSD1 RUNX3 CCND2 NF1

4.34e-031251554C0026998
DiseaseAcute Myeloid Leukemia (AML-M2)

NSD1 RUNX3 CCND2 NF1

4.34e-031251554C1879321
DiseaseChronic myeloproliferative disorder

JAK3 LIG4

4.42e-03191552C1292778
Diseaserenovascular hypertension (biomarker_via_orthology)

CCND2 CMA1

4.42e-03191552DOID:1591 (biomarker_via_orthology)
DiseaseOmenn Syndrome

JAK3 LIG4

4.42e-03191552C2700553
DiseaseSevere Combined Immunodeficiency

JAK3 LIG4

4.90e-03201552C0085110

Protein segments in the cluster

PeptideGeneStartEntry
HPQSKYLTILQKWIL

NAIP

1381

Q13075
RVNHVTLSQPKIVKW

B2M

101

P61769
SKWAVPFIQIKVLHN

EPG5

491

Q9HCE0
PLHTWLTVLKKEQEF

MS4A2

46

Q01362
QKWVRPVLHSNDTIK

CHRNB3

41

Q05901
HLFKFVNWSILLPEK

AADACL2

276

Q6P093
TFFEPISWHLATKVL

BTNL8

226

Q6UX41
VAKFINPDWIALHTS

ALG6

86

Q9Y672
FVTNITTKLPWHIKK

CASZ1

1251

Q86V15
IWSHAIQKYLEIPLK

ACTR8

211

Q9H981
ASIVPKGTHTWEKFV

COQ3

271

Q9NZJ6
IHDKNTPWKSFLVIV

GZF1

596

Q9H116
NKEAWPHIKTIFQGI

PGD

146

P52209
GSVPTFKHLWKQVAQ

ALDH4A1

286

P30038
PLVLVIKKWASHHQI

TENT2

306

Q6PIY7
QRKWTEAIAKHFVPL

ARAP2

991

Q8WZ64
PLQSRVWQTKSHALK

CCKAR

146

P32238
LIHWKSQVHPVLKLV

FBXL6

201

Q8N531
SVLISFIPVQLSWHK

DRD1

151

P21728
FIPVQLSWHKAKPTS

DRD1

156

P21728
HFQKVGKKPELTLVW

DIS3L2

806

Q8IYB7
VLDVVKAHKDSWPFL

CECR2

446

Q9BXF3
HKPTLTIKQKVIAWS

ARMCX5

211

Q6P1M9
HKALDPARWTIQKVF

AOC3

251

Q16853
PLWFSHTVANLRKLK

NWD1

716

Q149M9
HKVPQKILSKWEASV

NSD1

411

Q96L73
NHTVTLFWKPLSKLH

OSMR

446

Q99650
GHLVPASWKLQVVKQ

JAK3

616

P52333
IKSDSWKILPQSHLI

KBTBD3

316

Q8NAB2
WLHVNAKKSVFPKLS

LTN1

331

O94822
TAAAPKVLAILWFHS

OR52Z1P

61

P0C646
IVAFVSHPAWLQKLS

ANGPTL7

16

O43827
KLKWNLAAVTPHDFI

CCND2

146

P30279
FHINLFQVLPWLKEK

CFB

741

P00751
IVKSLIPSWNKLVFF

OGFOD1

196

Q8N543
WPSISHLAKDFIDKL

PSKH2

286

Q96QS6
VFTLVLKKVQPWHAG

MYLK

776

Q15746
FRSKIIHKNLNPVWE

MCTP1

296

Q6DN14
ALVWGLSVKHNPQKV

DRG1

336

Q9Y295
LKREWETLHNFPKVS

KCNMA1

886

Q12791
TAPSNLWKHQKLLSI

MBTPS1

941

Q14703
NIKIHPFFKTINWTL

PRKCD

596

Q05655
KKRLTTFQALQHPWV

CAMK4

286

Q16566
IHNESWVLLTPKAKE

ATRN

426

O75882
WKLQLHELTKLPAFV

KDM6A

1096

O15550
GITAFLQKRKPVWSH

ECHDC3

286

Q96DC8
KRIVNWHKLLVSPTQ

PCLO

5126

Q9Y6V0
LVVEAKKWTAVPSQH

PCSK6

486

P29122
ALTWKNLKPHIQGII

IPO7

336

O95373
IKCVIHNFWIPKESN

NEMP2

101

A6NFY4
KKSIFVFTHVLVPVW

NDUFB6

66

O95139
PTIQLFWKAFHKLTL

HERC6

926

Q8IVU3
IVKNLHLVVLKSWYP

MS4A10

81

Q96PG2
KPHFLKINVSELSLW

DPY19L1

326

Q2PZI1
SFVTHPWDVSLVQKI

DDX28

501

Q9NUL7
LNNLYKIIPKTLTWH

LY75

1111

O60449
HLFSWIQENASKLPK

LRRC38

196

Q5VT99
LQKLFWTGDPHLIKQ

NBAS

1851

A2RRP1
SKIDIHPTVLQVWFK

DPRX

51

A6NFQ7
EFLFSHLWPLIEKKV

IAH1

206

Q2TAA2
FLRTWLPAVIKIQAH

IQGAP3

756

Q86VI3
IKFFQLAAQWPTHVK

PACS1

936

Q6VY07
KLFHPLEQSIWAVKG

OSBPL8

211

Q9BZF1
IKLWFDKVGHQLIVT

RIMS2

811

Q9UQ26
VIVTPVSKLHFRVWS

ITCH

71

Q96J02
HLAAWLIPSVKSITA

FZD5

361

Q13467
FHLAAWAVPAVKTIT

FZD7

381

O75084
FHLAAWLVPSVKSIA

FZD8

441

Q9H461
TRKIWVPDIFFVHSK

GABRR3

136

A8MPY1
VKRFDPVKKTWHQVA

KLHL10

356

Q6JEL2
KTASVKVDFLWHPEV

CASD1

126

Q96PB1
NIILSNKHDVVKPAW

LIG4

711

P49917
LPEHWANTKKLAIQV

DNAH17

1171

Q9UFH2
DLTVNKTWVLAPKIH

GABRG1

46

Q8N1C3
TKINWKQFLTSFHEP

EFCAB6

351

Q5THR3
VLKHPFFWSLEKQLQ

ERN1

826

O75460
TKTHWKQTVFLLEKP

PRMT3

476

O60678
KWLHKSTSVFHPELV

GALNT5

881

Q7Z7M9
WNIFHSDPLIEKQKL

C5

1031

P01031
VKWTLAFLLHNPQVK

CYP17A1

311

P05093
HTWEEAPLLTLKQKQ

IL2RB

176

P14784
QNTKLAPETKAVIHW

CPE

221

P16870
HIVDLSDPKQIWKFV

DHRS12

96

A0PJE2
ITIFASAHPEKLTLW

IL12RB1

416

P42701
KYHVIAISTKNPLQW

MARCHF4

211

Q9P2E8
FLHNAITIPISPWKV

INSRR

716

P14616
KVSKLEWHPFTLTSA

CYBB

331

P04839
VHIFNAVSLRWTKLP

KLHDC3

46

Q9BQ90
EKTIVPWKSFRQALH

CBL

196

P22681
AKPLSWQHSKIIQAF

AHCTF1

836

Q8WYP5
FKSISWDPVKVHDIR

GPX5

166

O75715
SSFAKIKPAWVKADH

CES3

446

Q6UWW8
LKSLPLWAIVVAHFS

SLC17A5

286

Q9NRA2
IFVKSSVFPWHKNLL

SCAP

96

Q12770
KFIHTKPNRFEEVVW

NLGN2

556

Q8NFZ4
HQLWKPLAAVSLLAK

PPRC1

1236

Q5VV67
TSLWELKKLSVHFHP

CEBPZ

711

Q03701
TVLFSTAHKPWAEVI

LRRC43

451

Q8N309
TIHIKVGPQWKNKLS

OTOGL

1061

Q3ZCN5
VVFEKPVKTIHWNGS

PAOX

241

Q6QHF9
WQKEAEIHSKPVFIT

PTGFRN

806

Q9P2B2
SHWRCNKTLPVAFKV

RUNX3

81

Q13761
AITLPFVTVALAKHW

RTTN

1756

Q86VV8
PNHVVTLWGVLVKFD

RXFP4

261

Q8TDU9
NTWSPKLLHKFNDVV

SEC13

251

P55735
KTTHELKWPILGQLF

UTP25

211

Q68CQ4
DHTLKLWNLQKTVPA

STRN3

501

Q13033
KNLKSFIIVHPSWFI

PRUNE2

2991

Q8WUY3
SVKPFQVKNHIWVFI

TOP2B

371

Q02880
PVWLHKLSVVATFLI

LMF2

221

Q9BU23
VFFTLLWPGKVKVSV

NXPE3

171

Q969Y0
PHVLLAVAKLFWSQR

PRPF6

841

O94906
AWKVHIAKFSLLVGL

SLC22A23

226

A1A5C7
GVTFVVVLHQVWKKH

ITIH3

771

Q06033
FKIKSVPIISHSRWL

NGEF

476

Q8N5V2
ALSPQALKHVWVRTA

SGSM2

121

O43147
LEFQPSLKKQHLTWS

SHLD3

91

Q6ZNX1
RVTHKPNLLGSKWFI

RMND1

106

Q9NWS8
TWLEKLLPKTISQHQ

MT-ND5

556

P03915
AVHLLQAVLPSWDKT

HERC2P3

786

Q9BVR0
FASVSAHVSIWKVPV

SLC35E1

121

Q96K37
HVFPTDENIKRKWVL

THAP6

26

Q8TBB0
KVAQLPLFVSDGKWH

NPTX2

296

P47972
PEKASLSHVVWKFQR

ABCC12

106

Q96J65
LKKVENVSRSPWFTH

ABCC12

976

Q96J65
SPYWLKVKHVVNLVV

SCN1A

751

P35498
KISKEHWNPTIVALV

PPP2R5A

401

Q15172
HIKLPSSFEKWEIAR

CCDC15

716

Q0P6D6
AKTKQAWNFLSHLPV

ASCC3

2021

Q8N3C0
DTWQKLEVIKQFRHP

CMA1

86

P23946
LTLIINPYWTHKKTQ

CLN8

241

Q9UBY8
VSQAWRHALPFTKIL

CHST5

351

Q9GZS9
FLEQLVKKPNWAHSV

C12orf42

166

Q96LP6
TLKSFPAAIEHTIQW

UBA6

626

A0AVT1
FKWQTKPKLTIHGDL

SF3B2

576

Q13435
VIRLQPSWKHKLSQA

TSC1

96

Q92574
IWNKTKHDVKFPLDS

UBFD1

91

O14562
WPEHSIKDSFQKVIL

ZNF92

86

Q03936
KFDLWSLPKILVVHL

USP4

811

Q13107
ITLTKPNFAKHIVWA

ZC3H6

866

P61129
VKKLWDTFHVPVFTL

SPO11

261

Q9Y5K1
LWDPAKRTSVFIQVH

TFCP2

176

Q12800
HEENITWKFKVSKIP

TAS2R9

161

Q9NYW1
VATEKKLPLWQHARS

PLEKHG4B

761

Q96PX9
ALQTLKLDHPKIAAW

REXO5

706

Q96IC2
SPVFVIQKKSGKWHT

ERVK-10

71

P10266
NVLPVKTKWSNVGFH

WDR72

666

Q3MJ13
VFKDWSVVIEKLHPA

TTC41P

241

Q6P2S7
WKSQFKVHLKVPTGE

ZNF585B

141

Q52M93
NKDSPLHKALFWVAV

NF1

2306

P21359
LAASWYHKVPVVEIK

VPS13C

1331

Q709C8
SITVPQKKWLHFISP

TMEM165

221

Q9HC07
QKKWLHFISPIFVQA

TMEM165

226

Q9HC07
WPATSHIIGKDILKF

MARS2

301

Q96GW9
DHIWQKTLTVLHPLK

YIPF5

101

Q969M3
IHDVPSSLWKSKLLV

UNC5A

656

Q6ZN44
HWDPVSLISHALKQK

MTFR2

306

Q6P444
VVHPTSFIKVLWNIL

ARHGAP8

141

P85298
PKVRFITKIWHPNIS

UBE2K

71

P61086
LVVSTALIWHPINKL

TSPO2

116

Q5TGU0
SVAIKLVHNLTSPKW

VPS13B

3041

Q7Z7G8
FKWPSTLTIHKIIHT

ZNF85

491

Q03923
PVNSKIHDIFKGWSL

THSD7B

1531

Q9C0I4
TIIPHLSTWDQRKKQ

TRANK1

431

O15050
YKVHLDLWVKSLSPQ

UBTF

626

P17480
IKINIWLRVFSHSSP

SMAD5-AS1

31

Q9Y6J3
KKDHSHTPWIVIIAK

NAE1

206

Q13564
PTFSQEVLHKWKTDI

ZNF512

386

Q96ME7
KAPIHWTNVVKTAEI

VPS13D

3111

Q5THJ4
TPRHILVKFWNSSDK

L1TD1

756

Q5T7N2
KDILTTHPFTKISNW

MYO7A

2146

Q13402