Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmuscle alpha-actinin binding

PDLIM7 PDLIM5 PDLIM1

6.32e-05151063GO:0051371
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 DNAH7 DNAH12

1.12e-04181063GO:0008569
GeneOntologyMolecularFunctionDNA binding, bending

LEF1 FOXD1 FOXD4

1.55e-04201063GO:0008301
GeneOntologyMolecularFunctionneuroligin family protein binding

NRXN1 NRXN2

2.76e-0451062GO:0097109
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

NFASC PDLIM5 PDLIM1 PKP2

3.10e-04611064GO:0098632
GeneOntologyMolecularFunctionNADP binding

FMO1 CBR3 MTHFR FDXR

3.30e-04621064GO:0050661
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH2 GPR88 DNAH7 DNAH12 KIF1C

4.17e-041181065GO:0003774
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH7 DNAH12

4.32e-04281063GO:0051959
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH2 DNAH7 DNAH12 KIF1C

5.26e-04701064GO:0003777
GeneOntologyMolecularFunctionalpha-actinin binding

PDLIM7 PDLIM5 PDLIM1

5.87e-04311063GO:0051393
GeneOntologyMolecularFunctioncalcium ion binding

DUOX2 PKD1L2 DNAH7 ITIH1 RYR2 ITPR2 ARSA HMCN1 NRXN1 TLL1 TLL2 ITSN2

6.20e-0474910612GO:0005509
GeneOntologyMolecularFunctioncell adhesion mediator activity

NFASC PDLIM5 PDLIM1 PKP2

7.18e-04761064GO:0098631
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH7 DNAH12

9.91e-04371063GO:0045505
GeneOntologyMolecularFunctionactinin binding

PDLIM7 PDLIM5 PDLIM1

1.54e-03431063GO:0042805
GeneOntologyCellularComponentinner dynein arm

DNAH2 DNAH7 DNAH12

1.48e-05101063GO:0036156
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

IFT140 DNAH2 DNAH7 DNAH12 PIK3C3 RP1L1 CFAP74 FBXW11 KIF1C

3.43e-053171069GO:0032838
GeneOntologyCellularComponentcell-cell junction

PDLIM7 OBSL1 NFASC PARD3B KIRREL2 SHROOM2 PDLIM5 HMCN1 NRXN1 PDLIM1 PKP2 VASP

4.57e-0559110612GO:0005911
GeneOntologyCellularComponentaxoneme

IFT140 DNAH2 DNAH7 DNAH12 PIK3C3 RP1L1 CFAP74

8.98e-052071067GO:0005930
GeneOntologyCellularComponentcytoplasmic region

IFT140 DNAH2 DNAH7 DNAH12 PIK3C3 RP1L1 CFAP74 FBXW11 KIF1C

9.12e-053601069GO:0099568
GeneOntologyCellularComponentciliary plasm

IFT140 DNAH2 DNAH7 DNAH12 PIK3C3 RP1L1 CFAP74

9.25e-052081067GO:0097014
GeneOntologyCellularComponentadherens junction

PDLIM7 PARD3B SHROOM2 PDLIM5 HMCN1 PDLIM1 PKP2

1.04e-042121067GO:0005912
GeneOntologyCellularComponentaxonemal dynein complex

DNAH2 DNAH7 DNAH12

2.69e-04251063GO:0005858
GeneOntologyCellularComponentfilamentous actin

PDLIM7 PDLIM5 PDLIM1

9.40e-04381063GO:0031941
GeneOntologyCellularComponentZ disc

PDLIM7 OBSL1 PDLIM5 RYR2 PDLIM1

1.04e-031511065GO:0030018
GeneOntologyCellularComponentanchoring junction

PDLIM7 OBSL1 DUOX2 NFASC PARD3B KIRREL2 SHROOM2 PDLIM5 HMCN1 NRXN1 PDLIM1 PKP2 VASP

1.32e-0397610613GO:0070161
GeneOntologyCellularComponentfiltration diaphragm

KIRREL2 NRXN1

1.36e-03111062GO:0036056
GeneOntologyCellularComponentslit diaphragm

KIRREL2 NRXN1

1.36e-03111062GO:0036057
GeneOntologyCellularComponentmicrotubule associated complex

DNAH2 DNAH7 DNAH12 FBXW11 KIF1C

1.38e-031611065GO:0005875
GeneOntologyCellularComponentI band

PDLIM7 OBSL1 PDLIM5 RYR2 PDLIM1

1.58e-031661065GO:0031674
GeneOntologyCellularComponentsarcomere

PDLIM7 OBSL1 PDLIM5 RYR2 PDLIM1 MYOM2

1.70e-032491066GO:0030017
GeneOntologyCellularComponentA band

OBSL1 RYR2 MYOM2

2.34e-03521063GO:0031672
GeneOntologyCellularComponentsupramolecular fiber

PDLIM7 DNAH2 OBSL1 SHROOM2 DNAH7 PDLIM5 RYR2 DNAH12 PDLIM1 RP1L1 PKP2 MYOM2 FBXW11 KIF1C

2.51e-03117910614GO:0099512
GeneOntologyCellularComponentdynein complex

DNAH2 DNAH7 DNAH12

2.61e-03541063GO:0030286
GeneOntologyCellularComponentsupramolecular polymer

PDLIM7 DNAH2 OBSL1 SHROOM2 DNAH7 PDLIM5 RYR2 DNAH12 PDLIM1 RP1L1 PKP2 MYOM2 FBXW11 KIF1C

2.67e-03118710614GO:0099081
GeneOntologyCellularComponentmyofibril

PDLIM7 OBSL1 PDLIM5 RYR2 PDLIM1 MYOM2

2.69e-032731066GO:0030016
GeneOntologyCellularComponentcell tip

GPR179 PKP2

3.30e-03171062GO:0051286
GeneOntologyCellularComponentcontractile muscle fiber

PDLIM7 OBSL1 PDLIM5 RYR2 PDLIM1 MYOM2

3.63e-032901066GO:0043292
DomainIg_I-set

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.07e-0719010410IPR013098
DomainI-set

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.07e-0719010410PF07679
DomainTF_fork_head_CS_2

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.01e-07461046IPR030456
DomainTF_fork_head_CS_1

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.30e-07471046IPR018122
DomainFH

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.97e-07491046SM00339
DomainFORK_HEAD_1

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.97e-07491046PS00657
DomainFORK_HEAD_2

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.97e-07491046PS00658
DomainFork_head_dom

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.97e-07491046IPR001766
DomainFORK_HEAD_3

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.97e-07491046PS50039
DomainForkhead

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.97e-07491046PF00250
DomainIGc2

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

7.62e-0723510410SM00408
DomainIg_sub2

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

7.62e-0723510410IPR003598
Domainfn3

CHL1 BOC OBSL1 NFASC LRFN4 ROBO1 MYOM2

3.40e-051621047PF00041
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH7 DNAH12

5.84e-05141043IPR024317
DomainDynein_heavy_dom-2

DNAH2 DNAH7 DNAH12

5.84e-05141043IPR013602
DomainDHC_N2

DNAH2 DNAH7 DNAH12

5.84e-05141043PF08393
DomainAAA_8

DNAH2 DNAH7 DNAH12

5.84e-05141043PF12780
DomainDHC_fam

DNAH2 DNAH7 DNAH12

7.27e-05151043IPR026983
DomainDynein_heavy

DNAH2 DNAH7 DNAH12

7.27e-05151043PF03028
DomainDynein_heavy_dom

DNAH2 DNAH7 DNAH12

7.27e-05151043IPR004273
DomainFN3

CHL1 BOC OBSL1 NFASC LRFN4 ROBO1 MYOM2

7.90e-051851047SM00060
DomainBMP_1/tolloid-like

TLL1 TLL2

9.18e-0531042IPR015446
DomainIg-like_dom

CHL1 BOC VSIG2 PTCRA OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.13e-0450310411IPR007110
DomainIG

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.20e-0442110410SM00409
DomainIg_sub

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.20e-0442110410IPR003599
DomainFN3

CHL1 BOC OBSL1 NFASC LRFN4 ROBO1 MYOM2

1.25e-041991047PS50853
DomainFN3_dom

CHL1 BOC OBSL1 NFASC LRFN4 ROBO1 MYOM2

1.69e-042091047IPR003961
DomainNeurofascin/L1/NrCAM_C

CHL1 NFASC

1.83e-0441042IPR026966
DomainBravo_FIGEY

CHL1 NFASC

1.83e-0441042PF13882
Domain-

FOXD4L6 ADAR FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

2.18e-0421810471.10.10.10
DomainEGF

LAMA4 GPR179 HMCN1 NRXN1 NRXN2 TLL1 TLL2

3.45e-042351047SM00181
DomainWHTH_DNA-bd_dom

FOXD4L6 ADAR FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

4.11e-042421047IPR011991
DomainIG_LIKE

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

4.13e-0449110410PS50835
DomainRIH_assoc-dom

RYR2 ITPR2

4.54e-0461042IPR013662
DomainDUF4749

PDLIM5 PDLIM1

4.54e-0461042PF15936
DomainIns145_P3_rec

RYR2 ITPR2

4.54e-0461042PF08709
DomainRIH_assoc

RYR2 ITPR2

4.54e-0461042PF08454
DomainRIH_dom

RYR2 ITPR2

4.54e-0461042IPR000699
DomainIns145_P3_rcpt

RYR2 ITPR2

4.54e-0461042IPR014821
DomainRyanodine_recept-rel

RYR2 ITPR2

4.54e-0461042IPR015925
DomainPeptidase_M12A

TLL1 TLL2

4.54e-0461042IPR001506
DomainAstacin

TLL1 TLL2

4.54e-0461042PF01400
Domain-

RYR2 ITPR2

4.54e-04610421.25.10.30
DomainRYDR_ITPR

RYR2 ITPR2

4.54e-0461042PF01365
DomainDUF4749

PDLIM5 PDLIM1

4.54e-0461042IPR031847
DomainSyndecan

NRXN1 NRXN2

6.33e-0471042PF01034
DomainSyndecan/Neurexin_dom

NRXN1 NRXN2

6.33e-0471042IPR027789
DomainEGF

HMCN1 NRXN1 NRXN2 TLL1 TLL2

6.96e-041261045PF00008
DomainPDZ

PDLIM7 PARD3B SHROOM2 PDLIM5 PDLIM1

1.15e-031411045PF00595
Domain-

CHL1 BOC VSIG2 PTCRA OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.16e-03663104112.60.40.10
DomainLAM_G_DOMAIN

LAMA4 NRXN1 NRXN2

1.23e-03381043PS50025
DomainMIR

RYR2 ITPR2

1.34e-03101042PF02815
DomainAn_peroxidase

MPO DUOX2

1.34e-03101042PF03098
DomainMIR_motif

RYR2 ITPR2

1.34e-03101042IPR016093
DomainHaem_peroxidase_animal

MPO DUOX2

1.34e-03101042IPR019791
DomainMIR

RYR2 ITPR2

1.34e-03101042PS50919
DomainMIR

RYR2 ITPR2

1.34e-03101042SM00472
DomainHaem_peroxidase

MPO DUOX2

1.34e-03101042IPR010255
DomainPEROXIDASE_3

MPO DUOX2

1.34e-03101042PS50292
Domain-

MPO DUOX2

1.34e-031010421.10.640.10
DomainLaminin_G_2

LAMA4 NRXN1 NRXN2

1.43e-03401043PF02210
DomainPDZ

PDLIM7 PARD3B SHROOM2 PDLIM5 PDLIM1

1.43e-031481045SM00228
Domain-

PDLIM7 PARD3B SHROOM2 PDLIM5 PDLIM1

1.52e-0315010452.30.42.10
DomainPDZ

PDLIM7 PARD3B SHROOM2 PDLIM5 PDLIM1

1.56e-031511045PS50106
DomainPDZ

PDLIM7 PARD3B SHROOM2 PDLIM5 PDLIM1

1.61e-031521045IPR001478
DomainLamG

LAMA4 NRXN1 NRXN2

1.88e-03441043SM00282
DomainIg-like_fold

CHL1 BOC VSIG2 PTCRA OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.91e-0370610411IPR013783
DomainCUB

CSMD2 TLL1 TLL2

2.57e-03491043PF00431
DomainDynein_HC_stalk

DNAH2 DNAH7

2.68e-03141042IPR024743
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH12

2.68e-03141042IPR011704
DomainMT

DNAH2 DNAH7

2.68e-03141042PF12777
DomainNeurexin-like

NRXN1 NRXN2

2.68e-03141042IPR003585
Domain4.1m

NRXN1 NRXN2

2.68e-03141042SM00294
DomainAAA_5

DNAH2 DNAH12

2.68e-03141042PF07728
DomainEGF-like_dom

LAMA4 HMCN1 NRXN1 NRXN2 TLL1 TLL2

2.70e-032491046IPR000742
DomainCUB

CSMD2 TLL1 TLL2

2.72e-03501043SM00042
DomainEGF-type_Asp/Asn_hydroxyl_site

HMCN1 NRXN1 TLL1 TLL2

2.92e-031061044IPR000152
DomainEGF_1

LAMA4 HMCN1 NRXN1 NRXN2 TLL1 TLL2

3.04e-032551046PS00022
Domain-

CSMD2 TLL1 TLL2

3.04e-035210432.60.120.290
DomainCUB

CSMD2 TLL1 TLL2

3.21e-03531043PS01180
DomainEGF-like_CS

LAMA4 HMCN1 NRXN1 NRXN2 TLL1 TLL2

3.41e-032611046IPR013032
DomainCUB_dom

CSMD2 TLL1 TLL2

3.95e-03571043IPR000859
DomainLaminin_G

LAMA4 NRXN1 NRXN2

4.14e-03581043IPR001791
Domainig

CHL1 BOC OBSL1 NFASC HMCN1

4.22e-031901045PF00047
DomainImmunoglobulin

CHL1 BOC OBSL1 NFASC HMCN1

4.22e-031901045IPR013151
DomainIg_V-set

BOC VSIG2 KIRREL2 HMCN1 ROBO1

5.13e-031991045IPR013106
Pubmed

An amphioxus winged helix/forkhead gene, AmphiFoxD: insights into vertebrate neural crest evolution.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

6.49e-149108612412011
Pubmed

Cloning and characterization of seven human forkhead proteins: binding site specificity and DNA bending.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD1 FOXD4

1.31e-121310867957066
Pubmed

Neural transcription factors bias cleavage stage blastomeres to give rise to neural ectoderm.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.57e-126108527092474
Pubmed

The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.46e-11810858530406
Pubmed

A genetic study of the suppressors of the Engrailed-1 cerebellar phenotype.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

3.32e-1013108516884697
Pubmed

FOXD4a and FOXD4b, two new winged helix transcription factors, are expressed in human leukemia cell lines.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4

4.39e-105108412234674
Pubmed

Six members of the mouse forkhead gene family are developmentally regulated.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

7.70e-101510857689224
Pubmed

Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

7.70e-1015108522045912
Pubmed

Expression of the winged helix genes fkh-4 and fkh-5 defines domains in the central nervous system.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.12e-091610858861101
Pubmed

Developmental competence of the gut endoderm: genetic potentiation by GATA and HNF3/fork head proteins.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.12e-0916108510208738
Pubmed

Functional equivalency between Otx2 and Otx1 in development of the rostral head.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

2.95e-091910859895322
Pubmed

Forkhead transcription factor Foxf2 (LUN)-deficient mice exhibit abnormal development of secondary palate.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

3.93e-0920108512812790
Pubmed

Sequential roles for Otx2 in visceral endoderm and neuroectoderm for forebrain and midbrain induction and specification.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

5.14e-092110859449667
Pubmed

Crucial roles of Foxa2 in mouse anterior-posterior axis polarization via regulation of anterior visceral endoderm-specific genes.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

6.64e-0922108517389379
Pubmed

Otx2 is required to respond to signals from anterior neural ridge for forebrain specification.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.07e-0824108511820816
Pubmed

A Requirement for Zic2 in the Regulation of Nodal Expression Underlies the Establishment of Left-Sided Identity.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.07e-0824108529992973
Pubmed

Ssdp1 regulates head morphogenesis of mouse embryos by activating the Lim1-Ldb1 complex.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

1.64e-0826108515857913
Pubmed

Molecular profiling of synovial joints: use of microarray analysis to identify factors that direct the development of the knee and elbow.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

2.94e-0829108522972626
Pubmed

Genome-scale study of transcription factor expression in the branching mouse lung.

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3 LEF1 FOXD4

6.67e-0867108622711520
Pubmed

Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.

CHL1 BOC VSIG2 OBSL1 KIRREL2 LRFN4 HMCN1

7.85e-07162108725826454
Pubmed

Gene content and function of the ancestral chromosome fusion site in human chromosome 2q13-2q14.1 and paralogous regions.

FOXD4L4 FOXD4L3 FOXD4

4.72e-0611108312421752
Pubmed

Mutations in NRXN1 and NRXN2 in a patient with early-onset epileptic encephalopathy and respiratory depression.

NRXN1 NRXN2

9.55e-062108230709877
Pubmed

Mitochondrial calcium overload is a key determinant in heart failure.

RYR2 ITPR2

9.55e-062108226217001
Pubmed

Heterozygous deletion of α-neurexin I or α-neurexin II results in behaviors relevant to autism and schizophrenia.

NRXN1 NRXN2

9.55e-062108226595880
Pubmed

Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.

RYR2 ITPR2

9.55e-062108228158491
Pubmed

Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin.

NRXN1 NRXN2

9.55e-06210821621094
Pubmed

Multiple bone morphogenetic protein 1-related mammalian metalloproteinases process pro-lysyl oxidase at the correct physiological site and control lysyl oxidase activation in mouse embryo fibroblast cultures.

TLL1 TLL2

9.55e-062108211313359
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH7 DNAH12

1.03e-051410839373155
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PDLIM7 GPATCH1 PARD3B DNAH7 PDLIM5 PJA2 PDLIM1 ITSN2 TNRC6A USP54 RBFOX2 KIF1C

1.42e-058531081228718761
Pubmed

Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.

NRXN1 NRXN2

2.86e-053108238891114
Pubmed

Structural basis for the substrate specificity of bone morphogenetic protein 1/tolloid-like metalloproteases.

TLL1 TLL2

2.86e-053108218824173
Pubmed

alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.

NRXN1 NRXN2

2.86e-053108216406382
Pubmed

Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.

NRXN1 NRXN2

2.86e-053108231005376
Pubmed

Enigma proteins regulate YAP mechanotransduction.

PDLIM7 PDLIM5

2.86e-053108230404826
Pubmed

The interaction between the adaptor protein APS and Enigma is involved in actin organisation.

PDLIM7 PDLIM5

2.86e-053108215946664
Pubmed

Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.

NRXN1 NRXN2

2.86e-053108226446217
Pubmed

Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.

NRXN1 NRXN2

2.86e-053108211944992
Pubmed

Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.

NRXN1 NRXN2

2.86e-053108233058888
Pubmed

Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.

NRXN1 NRXN2

2.86e-053108217035546
Pubmed

Neurexins: three genes and 1001 products.

NRXN1 NRXN2

2.86e-05310829448462
Pubmed

Deletion of α-neurexin II results in autism-related behaviors in mice.

NRXN1 NRXN2

2.86e-053108225423136
Pubmed

Prevalence of arrhythmia-associated gene mutations and risk of sudden cardiac death in the Finnish population.

RYR2 PKP2

2.86e-053108223651034
Pubmed

Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.

NRXN1 NRXN2

2.86e-053108234133920
Pubmed

Association of the polymorphisms of MTHFR C677T, VDR C352T, and MPO G463A with risk for esophageal squamous cell dysplasia and carcinoma.

MPO MTHFR

2.86e-053108218662591
Pubmed

Truncating mutations in NRXN2 and NRXN1 in autism spectrum disorders and schizophrenia.

NRXN1 NRXN2

2.86e-053108221424692
Pubmed

The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.

NRXN1 NRXN2

2.86e-053108230858964
Pubmed

SCA8 mRNA expression suggests an antisense regulation of KLHL1 and correlates to SCA8 pathology.

TWNK ATXN8OS

2.86e-053108218708037
Pubmed

Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.

NRXN1 NRXN2

2.86e-053108228013231
Pubmed

Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.

NRXN1 NRXN2

2.86e-053108231812984
Pubmed

Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.

NRXN1 NRXN2

2.86e-053108212036300
Pubmed

β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.

NRXN1 NRXN2

2.86e-053108226213384
Pubmed

Neurexin gene family variants as risk factors for autism spectrum disorder.

NRXN1 NRXN2

2.86e-053108229045040
Pubmed

Plasminogen regulates pro-opiomelanocortin processing.

POMC PLG

2.86e-053108215099286
Pubmed

Assignment of TLL1 and TLL2, which encode human BMP-1/Tolloid-related metalloproteases, to chromosomes 4q32-->q33 and 10q23-->q24 and assignment of murine Tll2 to chromosome 19.

TLL1 TLL2

2.86e-053108210516436
Pubmed

Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.

NRXN1 NRXN2

2.86e-053108238571813
Pubmed

Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.

NRXN1 NRXN2

2.86e-053108235173587
Pubmed

Neurexins are differentially expressed in the embryonic nervous system of mice.

NRXN1 NRXN2

2.86e-05310827722633
Pubmed

Analysis of three functional polymorphisms in relation to osteoporosis phenotypes: replication in a Spanish cohort.

LCT MTHFR

2.86e-053108220390408
Pubmed

Diverse fates of paralogs following segmental duplication of telomeric genes.

FOXD4L4 FOXD4L3 FOXD4

4.30e-0522108315233989
Pubmed

Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.

IFT140 THSD7A NRXN1 NRXN2 ITSN2

5.53e-05130108512421765
Pubmed

Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.

NRXN1 NRXN2

5.71e-054108232706374
Pubmed

Pja2 Inhibits Wnt/β-catenin Signaling by Reducing the Level of TCF/LEF1.

PJA2 LEF1

5.71e-054108230021253
Pubmed

CASK: a novel dlg/PSD95 homolog with an N-terminal calmodulin-dependent protein kinase domain identified by interaction with neurexins.

NRXN1 NRXN2

5.71e-05410828786425
Pubmed

Deletion of alpha-neurexins does not cause a major impairment of axonal pathfinding or synapse formation.

NRXN1 NRXN2

5.71e-054108217347997
Pubmed

Mammalian tolloid proteinases: role in growth factor signalling.

TLL1 TLL2

5.71e-054108227391803
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

RYR2 ITPR2

5.71e-054108219120137
Pubmed

The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.

LYST RYR2

5.71e-05410829070932
Pubmed

Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.

NRXN1 NRXN2

5.71e-054108235385735
Pubmed

Neurexins regulate presynaptic GABAB-receptors at central synapses.

NRXN1 NRXN2

5.71e-054108233888718
Pubmed

Postsynaptic N-methyl-D-aspartate receptor function requires alpha-neurexins.

NRXN1 NRXN2

5.71e-054108214983056
Pubmed

iPS cells from Chediak-Higashi syndrome patients recapitulate the giant granules in myeloid cells.

MPO LYST

5.71e-054108236259166
Pubmed

Structural and functional evolution of the L1 family: are four adhesion molecules better than one?

CHL1 NFASC

5.71e-054108210662501
Pubmed

Neurexins cluster Ca2+ channels within the presynaptic active zone.

NRXN1 NRXN2

5.71e-054108232134527
Pubmed

Proximity labeling reveals dynamic changes in the SQSTM1 protein network.

PDLIM7 PSMA4 OBSL1 PDLIM5 PJA2 TNRC6A USP54

6.85e-05322108739098523
Pubmed

Canonical Wnt signaling regulates patterning, differentiation and nucleogenesis in mouse hypothalamus and prethalamus.

POMC LEF1 FOXD1

8.07e-0527108330063881
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DNAH2 CARD10 KIRREL2 SHROOM2 DNAH7 DYRK1B

9.18e-05233108637704626
Pubmed

Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.

NRXN1 NRXN2

9.50e-055108236709330
Pubmed

Trans-synaptic interaction of GluRdelta2 and Neurexin through Cbln1 mediates synapse formation in the cerebellum.

NRXN1 NRXN2

9.50e-055108220537373
Pubmed

Neuroligins and neurexins link synaptic function to cognitive disease.

NRXN1 NRXN2

9.50e-055108218923512
Pubmed

Human FOX gene family (Review).

FOXD1 FOXD4

9.50e-055108215492844
Pubmed

Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration.

NRXN1 NRXN2

9.50e-05510829223334
Pubmed

Conditional Deletion of All Neurexins Defines Diversity of Essential Synaptic Organizer Functions for Neurexins.

NRXN1 NRXN2

9.50e-055108228472659
Pubmed

A genome-wide association study of recipient genotype and medium-term kidney allograft function.

ZNF516 TRAV20

9.50e-055108223432519
Pubmed

The Gastric Mucosa from Patients Infected with CagA+ or VacA+ Helicobacter pylori Has a Lower Level of Dual Oxidase-2 Expression than Uninfected or Infected with CagA-/VacA- H. pylori.

MPO DUOX2

9.50e-055108227048452
Pubmed

Mammalian BMP-1/Tolloid-related metalloproteinases, including novel family member mammalian Tolloid-like 2, have differential enzymatic activities and distributions of expression relevant to patterning and skeletogenesis.

TLL1 TLL2

9.50e-055108210479448
Pubmed

Functional proteomics mapping of a human signaling pathway.

SUMF2 THSD7A PDLIM7 LAMA4 TWNK RYR2 CUEDC1 RNPEP PKP2

9.78e-05591108915231748
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

SLC25A46 PSMA4 OBSL1 ADAR RYR2 PLEKHH3 TNRC6A RBFOX2

1.01e-04462108831138677
Pubmed

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

CHL1 POMC CBR3 MYOM2 FOXD1

1.31e-04156108522008794
Pubmed

Chromosomal localization of six human forkhead genes, freac-1 (FKHL5), -3 (FKHL7), -4 (FKHL8), -5 (FKHL9), -6 (FKHL10), and -8 (FKHL12).

FOXD1 FOXD4

1.42e-04610828825632
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR2 ITPR2

1.42e-046108223463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR2 ITPR2

1.42e-046108225966694
Pubmed

Presynaptic α2δ-2 Calcium Channel Subunits Regulate Postsynaptic GABAA Receptor Abundance and Axonal Wiring.

NRXN1 NRXN2

1.42e-046108230683685
Pubmed

SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection.

HEY2 FBXW11

1.42e-046108217217622
Pubmed

Jerky/Earthbound facilitates cell-specific Wnt/Wingless signalling by modulating β-catenin-TCF activity.

JRK LEF1

1.42e-046108221399610
Pubmed

Gene polymorphisms and osteoporotic fractures: a study in postmenopausal French women.

LCT MTHFR

1.42e-046108219299182
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

NRXN1 NRXN2

1.42e-046108212827191
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR2 ITPR2

1.42e-046108220519450
Pubmed

Structures, alternative splicing, and neurexin binding of multiple neuroligins.

NRXN1 NRXN2

1.42e-04610828576240
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR2 ITPR2

1.42e-046108216844763
Pubmed

Recipient genetic determinants of inflammatory process and nonstandard atherosclerosis risk factors affect kidney graft function early posttransplantation.

MPO MTHFR

1.42e-046108219857676
Cytoband9q21.11

FOXD4L6 FOXD4L5 FOXD4L4 FOXD4L3

7.57e-073010849q21.11
Cytoband12p11

ITPR2 PKP2

1.95e-049108212p11
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 BOC VSIG2 OBSL1 NFASC KIRREL2 LRFN4 HMCN1 ROBO1 MYOM2

1.77e-091617810593
GeneFamilyDyneins, axonemal

DNAH2 DNAH7 DNAH12

5.03e-0517783536
GeneFamilyFibronectin type III domain containing

CHL1 BOC NFASC LRFN4 ROBO1 MYOM2

6.64e-05160786555
GeneFamilyBone morphogenetic proteins|Astacins

TLL1 TLL2

2.73e-046782894
GeneFamilyPDZ domain containing

PDLIM7 PARD3B SHROOM2 PDLIM5 PDLIM1

5.07e-041527851220
GeneFamilyImmunoglobulin like domain containing

CHL1 BOC OBSL1 KIRREL2 MYOM2

1.48e-03193785594
GeneFamilyLIM domain containing

PDLIM7 PDLIM5 PDLIM1

2.11e-03597831218
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CHL1 THSD7A SLC16A9 GPR85 NFASC CSMD2 SHROOM2 LYST RYR2 FOXD4L5 SLC6A1 NRXN1 NRXN2 TLL1 TNRC6A ROBO1 UNC79 RBFOX2

6.00e-07110610818M39071
CoexpressionHOSHIDA_LIVER_CANCER_SUBCLASS_S3

SELENBP1 VSIG2 TDO2 ITIH1 ITPR2 SLC6A1 ARSA PLG

1.49e-052661088M1286
CoexpressionHAY_BONE_MARROW_STROMAL

CHL1 BOC LAMA4 NFASC TDO2 GPR88 SLC6A1 GALNT17 NRXN1 NRXN2 TLL1 RBFOX2 FOXD1

1.67e-0576710813M39209
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDLIM7 NFASC PDLIM5 RYR2 SLC6A1 HMCN1 HEY2 MYOM2

2.14e-081901088d6b3a92119b210974a32af3fe9875d60eb02761e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POMC DUOX2 NFASC RYR2 GALNT17 NRXN1 MYOM2

9.16e-081521087bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

POMC DUOX2 NFASC RYR2 GALNT17 NRXN1 MYOM2

9.16e-081521087ee329249a034a969a16b26a224aa04249d67382d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 RYR2 HMCN1 NRXN1 ROBO1 MYOM2 UNC79

3.36e-0718410872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 RYR2 HMCN1 NRXN1 ROBO1 MYOM2 UNC79

3.36e-071841087ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 RYR2 HMCN1 NRXN1 ROBO1 MYOM2 UNC79

3.36e-0718410872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDLIM5 PLEKHH3 SLC6A1 PDLIM1 HEY2 MYOM2 LEF1

4.32e-071911087239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCellMesenchymal-vascular_smooth_muscle_cell|World / Lineage, Cell type, age group and donor

PDLIM7 NFASC RYR2 SLC6A1 HMCN1 HEY2 MYOM2

4.32e-071911087fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 NFASC PARD3B RYR2 GALNT17 HMCN1 ROBO1

4.32e-0719110876688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 NFASC PARD3B RYR2 GALNT17 HMCN1 ROBO1

4.48e-07192108799ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

NFASC PDLIM5 RYR2 PLEKHH3 SLC6A1 PDLIM1 HEY2

4.48e-0719210875000440dc1ed17e7474d340921bdff945646f27e
ToppCell10x3'2.3-week_12-13-Hematopoietic-MK-MK|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PTCRA PDLIM7 PDLIM5 DNAAF3 PDLIM1 PKP2 VASP

4.64e-0719310873d4411b3c1cb160dec5db29f0c126d8827dfe185
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

PDLIM7 LAMA4 NFASC CSMD2 RYR2 HMCN1 ROBO1

4.80e-07194108703a269f75a481ea54aea8e6444605db8d6df493d
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

LAMA4 NFASC PARD3B RYR2 GALNT17 HMCN1 ROBO1

4.97e-071951087603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 NFASC PARD3B RYR2 GALNT17 HMCN1 ROBO1

5.14e-0719610877d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

LAMA4 PARD3B CSMD2 RYR2 GALNT17 HMCN1 ROBO1

5.32e-071971087fb847f2277609c31fffcdf49517243ce0684facf
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

BOC LAMA4 NFASC RYR2 GALNT17 HMCN1 ROBO1

5.51e-07198108726e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMA4 NFASC PARD3B RYR2 GALNT17 HMCN1 ROBO1

5.51e-0719810878f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIRREL2 CBR3 GPR179 PLEKHH3 SLC6A1 DYRK1B

2.71e-0616110869f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO1 NFASC SLC6A1 HEY2 MYOM2 LEF1

3.83e-061711086285533ca2a6a411773313166bee35542f34d1a3c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD7A CARD10 PDLIM5 SLC6A1 GALNT17 PKP2

4.38e-061751086e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCellwk_15-18-Hematologic-Myeloid-aDC_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FOXD4L6 ITIH1 FOXD4L5 FOXD4L4 FOXD4L3 FOXD4

4.67e-061771086ccf5dc54780d6039a4d062dee88440c011ddc0a3
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

PHF20 TM9SF4 LAMA4 HMCN1 NRXN2 ROBO1

4.83e-061781086edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH2 AK9 DNAH7 DNAH12 NRXN1 CFAP74

4.99e-0617910865e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

THSD7A CARD10 PDLIM5 SLC6A1 GALNT17 PKP2

5.15e-061801086c6030e725e3d86d5d74a1676330c77ffeceb324f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC RYR2 HMCN1 PDLIM1 TLL1 ROBO1

5.66e-061831086dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC RYR2 HMCN1 PDLIM1 TLL1 ROBO1

5.66e-0618310864759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellwk_20-22-Epithelial-PNS-intermediate_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CHL1 THSD7A CARD10 KIRREL2 CSMD2 NRXN1

5.84e-0618410864e3ba64692868563a579902aa9c6f88cab5bce26
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

PDLIM7 NFASC PARD3B PDLIM5 RYR2 GALNT17

6.40e-061871086464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

LAMA4 NFASC RYR2 GALNT17 HMCN1 ROBO1

6.40e-06187108692d468dde81125d51daf7abd4703741abe1ab91c
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PDLIM5 SLC6A1 HMCN1 PDLIM1 HEY2 MYOM2

6.40e-061871086406ff9327d3109fe1e251629c4c617b00a573dc2
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 DNAH7 DNAAF3 DNAH12 CFAP74 PLG

6.40e-061871086bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

BOC LAMA4 RYR2 GALNT17 HMCN1 ROBO1

6.40e-061871086bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NFASC PDLIM5 PLEKHH3 PDLIM1 HEY2 MYOM2

7.01e-061901086a7f6c38bbf451f166febb21e6719d4afced4035e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PDLIM5 RYR2 PLEKHH3 SLC6A1 HEY2 MYOM2

7.01e-06190108610125091ad648163777b02e9f0d5e8d7f17d44a5
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

LAMA4 NFASC RYR2 GALNT17 HMCN1 ROBO1

7.01e-0619010863a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-0619110867b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-061911086fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-061911086ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-061911086b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-061911086c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class (2021.01.30)

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-061911086cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

CHL1 SELENBP1 DNAH2 DNAH7 DNAH12 CFAP74

7.23e-0619110866228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_pericyte_(14)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

NFASC PDLIM5 PLEKHH3 SLC6A1 HEY2 MYOM2

7.45e-06192108655f95454399fd533df75db06584eaa48d6ee3830
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PDLIM7 NFASC PDLIM5 SLC6A1 HMCN1 HEY2

7.45e-061921086a7d08416f07f29ad920168a3b52ddf992f263bf4
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA4 NFASC PARD3B RYR2 GALNT17 HMCN1

7.67e-061931086b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

BOC RYR2 GALNT17 HMCN1 ROBO1 RBFOX2

7.67e-061931086e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

LAMA4 NFASC RYR2 GALNT17 HMCN1 ROBO1

7.67e-061931086ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Vascular_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

PDLIM5 SLC6A1 HMCN1 PDLIM1 HEY2 MYOM2

7.67e-061931086360079cbaa18b74e4a48c5de40844faca076e1a6
ToppCell15-Airway-Mesenchymal-Pericyte|Airway / Age, Tissue, Lineage and Cell class

PDLIM7 PDLIM5 HMCN1 PDLIM1 HEY2 MYOM2

7.90e-0619410865c1218d239c88082496924653ed2a092dc44a906
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

LAMA4 NFASC RYR2 GALNT17 HMCN1 ROBO1

8.14e-06195108661c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

LAMA4 NFASC RYR2 GALNT17 HMCN1 ROBO1

8.14e-061951086aa0add081881d349099d12efca5cdee098038d4e
ToppCell10x3'2.3-week_14-16-Hematopoietic-MK-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

PTCRA PDLIM7 RYR2 DNAAF3 PDLIM1 VASP

8.38e-06196108666ba31b74953726e9c314f6d8fe3f75d3762e23a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM7 LAMA4 NFASC PDLIM5 SLC6A1 HMCN1

8.38e-061961086fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM7 LAMA4 NFASC PDLIM5 SLC6A1 HMCN1

8.38e-061961086802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

BOC PDLIM7 LAMA4 NFASC RYR2 MYOM2

8.38e-0619610869830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PDLIM7 LAMA4 NFASC PDLIM5 RYR2 SLC6A1

8.62e-061971086bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

LAMA4 CSMD2 RYR2 GALNT17 HMCN1 ROBO1

8.62e-061971086f1c8936986123a3151140c374fcd62d6705c530b
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDLIM7 NFASC PDLIM5 SLC6A1 PDLIM1 HEY2

8.62e-06197108615a08b04acb1cb7e84aeb072c650ce07374181f5
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH2 AK9 DNAH7 DNAAF3 DNAH12 CFAP74

8.87e-061981086ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

BOC LAMA4 RYR2 GALNT17 HMCN1 ROBO1

9.13e-0619910864bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Intermediate|GW10 / Sample Type, Dataset, Time_group, and Cell type.

PARD3B ASB12 DNAH7 CACNA2D4 PKP2 MAP3K15

9.13e-061991086cf592d93612023a13de21e0fb8c6b13714f9af71
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PDLIM7 CSMD2 PDLIM5 RYR2 PLEKHH3 SLC6A1

9.40e-0620010869169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CHL1 VIPR1 THSD7A HMCN1 TLL1 HEY2

9.40e-0620010867547d6339f9380d031cfd2cce21ac9a12491e085
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

THSD7A PDLIM5 HMCN1 PDLIM1 ITSN2 USP54

9.40e-06200108665b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal|GW09 / Sample Type, Dataset, Time_group, and Cell type.

THSD7A GPR85 NFASC NRXN1 UNC79 RBFOX2

9.40e-06200108609fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCellLV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

PDLIM5 RYR2 GALNT17 PKP2 MYOM2

1.64e-051301085a3e12984fb61311e49cc76c59f74f4dffc48faa1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VSIG2 DUOX2 LCT HMCN1

3.35e-057510843167beedef7304697e9577270cdeacfc9743cee1
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VSIG2 DUOX2 LCT HMCN1

3.35e-0575108470c346f92a9ac7e33fc1b9dee1dca0bf9ae0a38c
ToppCellGlobus_pallidus-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Car4_(Car4)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

VSIG2 DUOX2 LCT HMCN1

3.35e-0575108426d6e54ed0a6c3ff57f6269c460177bc7b8bf979
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Lypd1_Gpr88|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BOC THSD7A VSIG2 GPR88 GALNT17

4.05e-0515710855aee90ad7aaa65fdabc23597451da5e48db8f4e6
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

PTCRA LCT LYST LEF1 TRAV20

4.70e-051621085a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCellCiliated_cells-B-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 DNAH7 DNAAF3 DNAH12 HEY2

4.70e-0516210855319603f7ba3f48126dcf2ba9ae604be11bf2577
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PDLIM7 NFASC PDLIM5 SLC6A1 MYOM2

4.84e-05163108551dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 MPO RYR2 HMCN1 UNC79

5.13e-0516510856d315e0734079ad05336cc2c3f24d870c9105bc8
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 MPO RYR2 HMCN1 UNC79

5.13e-05165108584f5597b1bb75f42de9a224196bb8ac198bbe3bf
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

THSD7A LAMA4 NFASC CARD10 RYR2

5.43e-0516710856a03d16165e0b003092c39972928981abd4a75aa
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXD4L6 ITIH1 FOXD4L4 FOXD4L3 FOXD4

5.59e-0516810856dd58fd981750da49afd53796f244e1803cce97f
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NFASC CSMD2 ITIH1 NRXN1 UNC79

5.75e-05169108596a2aec9acf8a6f966973c035e5ade456cf47772
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-promyelocyte|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MPO VIPR1 SUMF2 OBSL1 LYST

5.75e-051691085f33f4a0baad1b3cb5be61dfc7b00c7a3845f7120
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH2 AK9 DNAH7 DNAH12 CFAP74

5.75e-05169108514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellCOVID-19-Heart-CM_+_Macrophage|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDLIM5 RYR2 GALNT17 PKP2 MYOM2

5.91e-0517010853f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCellNasal_Brush-Epithelial-Ionocytes|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA4 ITPR2 ROBO1 LEF1 ZNF662

6.25e-05172108504fabb40fa9357d8902f3b04adc15231626cd9f8
ToppCellNasal_Brush-Epithelial-Ionocytes|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMA4 ITPR2 ROBO1 LEF1 ZNF662

6.25e-051721085dd3a23dc78dc6939f41126f8d7bd23a2e4713647
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

PDLIM7 NFASC RYR2 GALNT17 MYOM2

6.42e-051731085a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RYR2 SLC6A1 HMCN1 HEY2 MYOM2

6.60e-051741085015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHL1 CSMD2 CACNA2D4 NRXN1 MAP3K15

6.78e-0517510858362a46f5804333baa84cd56d450bc147f372a7e
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CHL1 CSMD2 CACNA2D4 NRXN1 MAP3K15

6.78e-0517510858b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM2 CACNA2D4 HMCN1 LSS LEF1

6.96e-0517610857292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHROOM2 CACNA2D4 HMCN1 LSS LEF1

6.96e-05176108588ca2f83d8301633232735f39b0683efe49d0b86
ToppCellwk_20-22-Hematologic-Myeloid-aDC_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FOXD4L6 ITIH1 FOXD4L4 FOXD4L3 FOXD4

7.35e-051781085fd2bdb4796e86c8cff2d25f0c730ffea21db8787
ToppCellCiliated_cells-A-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAH2 DNAH7 DNAAF3 DNAH12 CFAP74

7.54e-0517910850e6c22de2e3fb0ff23b3301863cf4011c5c59dff
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FOXD4L5 FOXD4L4 FOXD4L3 ROBO1 FOXD4

7.74e-05180108532d871738a24071b70084a7e80148a516110c78b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FOXD4L5 FOXD4L4 FOXD4L3 ROBO1 FOXD4

7.74e-051801085067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIRREL2 PDLIM5 SLC6A1 HEY2 MYOM2

7.74e-0518010854fb95ed39508bede5472dd36aeabe91b33631726
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 CBR3 FOXD4L5 HMCN1 NRXN1

7.95e-051811085a436e7e4c36403257ea90160a58ca0d6d7c0cdfc
ToppCellCOVID-19-Heart-CM_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

PDLIM5 RYR2 GALNT17 PKP2 MYOM2

7.95e-051811085719eb532453ab7cd7893726885bc75d74a10b21e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA4 RYR2 GALNT17 HMCN1 ROBO1

7.95e-0518110859ede19228ba5c0668a9c06c915510b95585216ef
ToppCellAdult-Epithelial-ciliated_cell-D122|Adult / Lineage, Cell type, age group and donor

DNAH2 DNAH7 DNAH12 CFAP74 PLG

8.16e-0518210857ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC25A46 CAD CBR3 FDXR LEF1

8.59e-051841085a6dee97ee4ef9d89e11d17339e0dadaea1210ce5
DiseaseMyoclonic Astatic Epilepsy

POMC SLC6A1 TNRC6A

6.30e-06111013C0393702
DiseaseSchizophrenia

CHL1 SELENBP1 NFASC TDO2 CSMD2 ITIH1 PDLIM5 SLC6A1 NRXN1 NRXN2 PIK3C3 MTHFR PLG

1.02e-0588310113C0036341
DiseaseMajor Depressive Disorder

MPO TDO2 ITIH1 PDLIM5 ARSA MTHFR PLG

2.10e-052431017C1269683
DiseaseUnipolar Depression

POMC TDO2 ITIH1 PDLIM5 ARSA MTHFR PLG

3.16e-052591017C0041696
DiseaseArrhythmogenic Right Ventricular Dysplasia

RYR2 PKP2

3.47e-0531012C0349788
Diseasemyofibrillar myopathy 4 (implicated_via_orthology)

PDLIM7 PDLIM5

3.47e-0531012DOID:0080095 (implicated_via_orthology)
DiseaseBipolar Disorder

THSD7A POMC TDO2 ITIH1 PDLIM5 NRXN1 PIK3C3 MTHFR TLL2

3.92e-054771019C0005586
Diseasenephrotic syndrome (implicated_via_orthology)

COQ8B KIRREL2 ITSN2

7.48e-05241013DOID:1184 (implicated_via_orthology)
DiseaseManic Disorder

THSD7A POMC ITIH1 MTHFR

1.05e-04711014C0024713
DiseaseManic

THSD7A POMC ITIH1 MTHFR

1.52e-04781014C0338831
DiseaseDepression, Bipolar

THSD7A POMC ITIH1 MTHFR

1.60e-04791014C0005587
Diseasethrombophilia (is_implicated_in)

MTHFR PLG

1.72e-0461012DOID:2452 (is_implicated_in)
Diseaserenal transplant outcome measurement

ZNF516 TRAV20

1.72e-0461012EFO_0005199
Diseaseprimary ciliary dyskinesia (is_implicated_in)

DNAH7 CFAP74

1.72e-0461012DOID:9562 (is_implicated_in)
DiseaseMASA syndrome (implicated_via_orthology)

CHL1 NFASC

2.41e-0471012DOID:0060246 (implicated_via_orthology)
DiseaseAutistic Disorder

POMC TDO2 NRXN1 NRXN2 MTHFR ROBO1

2.84e-042611016C0004352
DiseaseEarly Childhood Epilepsy, Myoclonic

POMC TNRC6A

3.20e-0481012C0393695
DiseaseIdiopathic Myoclonic Epilepsy

POMC TNRC6A

3.20e-0481012C0338478
DiseaseSymptomatic Myoclonic Epilepsy

POMC TNRC6A

3.20e-0481012C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

POMC TNRC6A

3.20e-0481012C0751120
DiseaseMyoclonic Encephalopathy

POMC TNRC6A

3.20e-0481012C0438414
DiseaseMyoclonic Absence Epilepsy

POMC TNRC6A

3.20e-0481012C0393703
DiseaseAcute kidney injury

MPO POMC MTHFR PLG

4.09e-041011014C2609414
DiseaseAcute Kidney Insufficiency

MPO POMC MTHFR PLG

4.09e-041011014C1565662
DiseaseKidney Failure, Acute

MPO POMC MTHFR PLG

4.09e-041011014C0022660
Diseasefamilial Mediterranean fever (is_implicated_in)

POMC MTHFR

4.11e-0491012DOID:2987 (is_implicated_in)
DiseaseMyoclonic Epilepsy

POMC TNRC6A

4.11e-0491012C0014550
Diseaseliver cirrhosis (is_implicated_in)

MPO ADAR MTHFR

4.35e-04431013DOID:5082 (is_implicated_in)
Diseasearrhythmogenic right ventricular cardiomyopathy (is_implicated_in)

RYR2 PKP2

5.13e-04101012DOID:0050431 (is_implicated_in)
DiseaseEpilepsy, Myoclonic, Infantile

POMC TNRC6A

5.13e-04101012C0917800
DiseaseEndogenous depression

PDCD2 POMC MTHFR

5.31e-04461013C0011573
Diseaseunipolar depression, information processing speed, cognitive function measurement

SLC25A46 MPO ROBO1

5.66e-04471013EFO_0003761, EFO_0004363, EFO_0008354
DiseaseQRS duration

OBSL1 PDLIM5 CACNA2D4 HMCN1 SKOR2 MYOM2

5.73e-042981016EFO_0005055
DiseaseLong QT Syndrome

POMC RYR2

6.25e-04111012C0023976
Diseasemetabolite measurement

FMO1 SLC16A9 PKD1L2 SHROOM2 PDLIM5 ITPR2 ARSA RNPEP

6.90e-045601018EFO_0004725
Diseasenervous system disease (implicated_via_orthology)

SKOR2 KIF1C

7.49e-04121012DOID:863 (implicated_via_orthology)
DiseaseGastrointestinal Diseases

POMC MTHFR

7.49e-04121012C0017178
DiseaseFunctional Gastrointestinal Disorders

POMC MTHFR

7.49e-04121012C0559031
DiseaseCholera Infantum

POMC MTHFR

7.49e-04121012C1565321
DiseaseInfantile Severe Myoclonic Epilepsy

POMC TNRC6A

8.83e-04131012C0751122
DiseaseBrugada Syndrome 1

HEY2 PKP2

8.83e-04131012C4551804
Diseasehypothyroidism (implicated_via_orthology)

DUOX2 ARSA

8.83e-04131012DOID:1459 (implicated_via_orthology)
DiseaseHypertrophic Cardiomyopathy

POMC RYR2 HEY2

9.96e-04571013C0007194
DiseaseCardiomyopathies

POMC LAMA4 RYR2 PKP2

1.06e-031301014C0878544
DiseaseMalignant neoplasm of breast

BOC PDLIM7 SHROOM2 ADAR MTHFR TLL1 ITSN2 HEY2 ROBO1 USP54 LEF1

1.13e-03107410111C0006142
Diseaseidiopathic dilated cardiomyopathy

BOC THSD7A PARD3B

1.16e-03601013EFO_0009094
DiseaseSinus Node Dysfunction (disorder)

POMC PKP2

1.18e-03151012C0428908
Diseaseresponse to bronchodilator, FEV/FEC ratio

MPO THSD7A PSMA4 PARD3B LYST GALNT17 NRXN1 RNPEP RP1L1

1.27e-037661019EFO_0004713, GO_0097366
Diseasesporadic amyotrophic lateral sclerosis

NFASC PDLIM5 MYOM2 LEF1

1.39e-031401014EFO_0001357
DiseaseNight blindness, congenital stationary

GPR179 CACNA2D4

1.53e-03171012C0339535
DiseaseSchizophrenia

NRXN1 MTHFR

1.71e-03181012cv:C0036341
DiseaseMental Depression

POMC CSMD2 SLC6A1 NRXN1 MTHFR

1.84e-032541015C0011570
Diseasecystathionine measurement

VSIG2 PARD3B

1.91e-03191012EFO_0010474
DiseaseAlopecia

MTHFR LSS

1.91e-03191012C0002170
Diseaseage at first sexual intercourse measurement

NFASC DNAAF3 NRXN1 SKOR2 TNRC6A UNC79

2.07e-033831016EFO_0009749
Diseaseintellectual disability (implicated_via_orthology)

ITSN2 DYRK1B RBFOX2

2.20e-03751013DOID:1059 (implicated_via_orthology)
Diseasesusceptibility to strep throat measurement

LAMA4 DNAAF3 ATXN8OS

2.28e-03761013EFO_0008408
DiseaseDeep Vein Thrombosis

MTHFR PLG

2.33e-03211012C0149871
DiseaseVenous Thrombosis

MTHFR PLG

2.33e-03211012C0042487
Diseasecardiovascular system disease (is_implicated_in)

MPO MTHFR

2.33e-03211012DOID:1287 (is_implicated_in)
Diseasecoronary artery disease

IFT140 CWF19L2 THSD7A PTCRA DUOX2 PDLIM5 DNAAF3 NRXN1 ATXN8OS MTHFR PLG

2.60e-03119410111EFO_0001645
DiseaseMorbilliform Drug Reaction

MPO MTHFR

2.80e-03231012C0406537
DiseaseDrug Eruptions

MPO MTHFR

2.80e-03231012C0011609
Diseasehippocampal sclerosis of aging

THSD7A CUEDC1

2.80e-03231012EFO_0005678
Diseasecongenital heart disease (is_implicated_in)

TLL1 RBFOX2

3.05e-03241012DOID:1682 (is_implicated_in)
DiseaseBrugada Syndrome (disorder)

HEY2 PKP2

3.05e-03241012C1142166
DiseaseAutism Spectrum Disorders

RYR2 NRXN1 NRXN2

3.14e-03851013C1510586
DiseaseDepressive disorder

POMC CSMD2 SLC6A1 NRXN1 MTHFR

3.21e-032891015C0011581
DiseaseHypertrophic obstructive cardiomyopathy

POMC HEY2

3.31e-03251012C4551472

Protein segments in the cluster

PeptideGeneStartEntry
EAWAKGPGAEPFYIR

CARD10

696

Q9BWT7
LATGEKLFGPYVWGR

RNPEP

271

Q9H4A4
GTILSPGWPGFYKDA

CSMD2

761

Q7Z408
PGLYCSGWVKRGPTG

FDXR

391

P22570
PKARKYFERLPGGGW

DYRK1B

341

Q9Y463
VWHLYGGKDFGIVPP

ATG2B

1556

Q96BY7
NGWKLSPVVGAVYGP

RBFOX2

211

O43251
IPREPGNPGKGNYWT

FOXD1

186

Q16676
GGRGWFPKSYVKIIP

ITSN2

941

Q9NZM3
PRFKEALGGPAWDYR

ITPR2

1586

Q14571
LGWQGQPVYPITGGF

LEF1

211

Q9UJU2
VHLSGPGGPVRWYKD

OBSL1

1291

O75147
PGGPVRWYKDGERLA

OBSL1

1296

O75147
GTNNKPYRPWGTEVG

HEY2

321

Q9UBP5
LGNSLGPPIVGWFYD

SLC16A9

441

Q7RTY1
YDLLWVPGRGPDGNA

PARD3B

1056

Q8TEW8
PIVGWGPSGGYVFQK

MTHFR

496

P42898
GGGQITYKWPPNDRP

NRXN1

96

P58400
GRKPGSPVWGEGSYL

PTCRA

226

Q6ISU1
PPADWDGAGGSYRLL

GPR88

101

Q9GZN0
NGPGLEYRVTWKPQG

CHL1

741

O00533
ITLNPGFGGPVFSWR

ITIH1

751

P19827
LGSLGSPKWPQADGY

GPR179

206

Q6PRD1
REPGHPGKGNYWSLD

FOXD4L4

171

Q8WXT5
REPGHPGKGNYWSLD

FOXD4L3

171

Q6VB84
GPPVEGDGWLKSFQR

ATXN8OS

81

P0DMR3
YKRFINSRSGWGVPG

ASB12

51

Q8WXK4
VVEDLRDYWPGPGKF

DUOX2

406

Q9NRD8
PGDGLYGWTAPRQYK

GPATCH1

316

Q9BRR8
QFPSKVGGRPAWLGA

PDCD2

26

Q16342
WFLGKRSEGVPVSGP

JRK

96

O75564
GFSLPYGWTPGVKRN

MPO

206

P05164
YGWTPGVKRNGFPVA

MPO

211

P05164
RELNPYWKDGGTGLP

CWF19L2

196

Q2TBE0
AGPGPGDQESRWKQY

CUEDC1

216

Q9NWM3
GWDQYLFKNRPTDGP

FBXW11

186

Q9UKB1
RQPPGKGLEWIGSIY

IGHV4-39

66

P01824
GGPYKTEPATDLGRW

LSS

11

P48449
FGKGGALITYTWPPN

NRXN2

1141

Q9P2S2
FRWGSPPKDKRYGGF

POMC

226

P01189
KFGPLGWNIPYGFNE

DNAH12

2661

Q6ZR08
YGKPDGPGDAWRAVA

KIF1C

786

O43896
WLGYGSGEFPPGVKD

LCT

1071

P09848
YEGGVREPALAFWPG

ARSA

306

P15289
FPWFSPGGSGLRGLK

TWNK

206

Q96RR1
PAPWGFRLQGGKDFN

PDLIM5

11

Q96HC4
GGGQITYKWPPNDRP

NRXN1

1131

Q9ULB1
PREPGRPGKGNYWSL

FOXD4

166

Q12950
PAPWGFRLQGGKDFN

PDLIM7

11

Q9NR12
PIWGKLTVYRGGGYV

PKD1L2

2091

Q7Z442
FKGDYPSNWIEPLGG

HMCN1

4351

Q96RW7
GKGGALITYTWPPND

NRXN2

96

P58401
SGVPTPDIAWYKKGG

NFASC

271

O94856
SVYVTWIPRGNGGFP

BOC

621

Q9BWV1
FRFWAGGEKGPQAFP

DNAAF3

171

Q8N9W5
PKFVYQAKVGGRWFP

ADAR

756

P55265
FRIYPGIKWTPDENG

CACNA2D4

256

Q7Z3S7
YQFRLTGPGKWEGAR

FMO1

471

Q01740
ERRKFGPLGWNIPYE

DNAH7

3591

Q8WXX0
GWGPQLARYTKEGFL

GALNT17

496

Q6IS24
WAQKFYQDGPGRGLG

COQ8B

41

Q96D53
GLKWGEYVGSPSAPV

LYST

3466

Q99698
REGWPNSPYGVSKLG

CBR3

186

O75828
TAQPPVTGYRWAKGG

KIRREL2

251

Q6UWL6
YWRVFARGPVVPGGF

GPR85

306

P60893
YHFARWEDGKQGPLP

DNAH2

396

Q9P225
VSKGYPDIGWNPVEG

RYR2

2281

Q92736
WRKVPDFLGSPGAEG

IFT140

351

Q96RY7
GKRPFGVSLLYIGWD

PSMA4

126

P25789
WGREFQGRPFNSKPE

CFAP74

506

Q9C0B2
LFGKWHEGLYRGPTP

OSBPL7

701

Q9BZF2
PGPWGFRLVGGKDFE

PDLIM1

11

O00151
WKIKGPIYLGGVAPG

LAMA4

1586

Q16363
VCQDPPGQRPGFKYW

PHF20

696

Q9BVI0
IDQGPRGYGAPADIW

MAP3K15

821

Q6ZN16
DRFPGAPKYGGWIVD

AK9

621

Q5TCS8
VEKAFWRQPAGPGSG

SUMF2

121

Q8NBJ7
FAARGGLKGQVYPWG

SUMF2

171

Q8NBJ7
IVVKGWLYREPRGGG

PLEKHH3

96

Q7Z736
PLTMGNYVFPKWGQG

SLC6A1

521

P30531
IWPGGVIPYVIGGNF

TLL1

156

O43897
QPFGPDGRLKTWVYG

THSD7A

1596

Q9UPZ6
RTPGLEPHGFNFWGK

TDO2

211

P48775
REPGHPGKGNYWSLD

FOXD4L5

171

Q5VV16
REPGHPGKGNYWSLD

FOXD4L6

171

Q3SYB3
WDVYGPGKAVPVGGT

PIK3C3

111

Q8NEB9
AAPGRSNFGPVWYVP

SHROOM2

291

Q13796
FEVKGTWERPGGAAP

SELENBP1

171

Q13228
TWERPGGAAPLGYDF

SELENBP1

176

Q13228
GDVGGPWCYTTNPRK

PLG

536

P00747
PGWAGYLPRAKVTEF

C10orf82

106

Q8WW14
SYGKLQEPWGRPQEG

C11orf86

16

A6NJI1
ALWAPGPDGYRQTKP

ZNF516

876

Q92618
VLGWNPKYRHPSGGS

VIPR1

411

P32241
LRGLFWYRQDPGKGP

TRAV20

51

A0A0B4J274
WYRQDPGKGPEFLFT

TRAV20

56

A0A0B4J274
GWKLVHGDVFRPPQY

TM9SF4

326

Q92544
GRGGQPGPKYEIWTN

RP1L1

396

Q8IWN7
GSRNLHWGEKSPPYG

SLC25A46

51

Q96AG3
KERGWNDPPQFSYGL

SRA1

11

Q9HD15
ERIWPGGVIPYVIGG

TLL2

156

Q9Y6L7
AEGRPTPTIEWYKGG

ROBO1

91

Q9Y6N7
VPPGYGQDVRKWPQG

CAD

1801

P27708
SGLFWPAGRKDAFYP

SKOR2

451

Q2VWA4
GAPKPVYNWVRLGTF

VSIG2

171

Q96IQ7
SGWPEGDYPKANGLL

PKP2

536

Q99959
WPKPAGGYQTITGRR

PJA2

21

O43164
EGHWYPEKPLKGSGF

TOB2

41

Q14106
EFRPGEPWKGYPNID

TNRC6A

1611

Q8NDV7
GTRGPCPDWEYVFKN

ZNF583

71

Q96ND8
EKSRLGRWPGYLNGG

ZNF662

131

Q6ZS27
IKFGGPSPQYKRWGP

USP54

626

Q70EL1
YDDGNKRWLPAGTGP

VASP

16

P50552
WPNLKPPGAISEYRG

UNC79

281

Q9P2D8
PGLAGRYFWAVPEGE

LRFN4

261

Q6PJG9
WKVPKFSGGSPILGY

MYOM2

731

P54296