Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmesenchyme migration

ACTA1 ACTA2 ACTC1

1.67e-0651153GO:0090131
GeneOntologyBiologicalProcesstissue morphogenesis

NCOA3 MAGED1 ACTA1 ACTA2 FRS2 ACTC1 PLXND1 RUNX3 ARID1A CELSR1 SULF1 PKHD1 DCHS1 ROBO2 PCDH8 NOTCH4

4.16e-0675011516GO:0048729
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

NCOA3 MAGED1 FRS2 PLXND1 CELSR1 SULF1 PKHD1 DCHS1 NOTCH4

7.08e-062361159GO:0061138
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

NCOA3 MAGED1 FRS2 PLXND1 CELSR1 SULF1 PKHD1 DCHS1 NOTCH4

1.45e-052581159GO:0001763
GeneOntologyBiologicalProcessmesenchyme morphogenesis

ACTA1 ACTA2 ACTC1 DCHS1 ROBO2

3.12e-05651155GO:0072132
GeneOntologyBiologicalProcessregulation of animal organ morphogenesis

MAGED1 FRS2 CELSR1 SULF1 PKHD1 ROBO2

3.52e-051101156GO:2000027
GeneOntologyBiologicalProcessnuclear receptor-mediated glucocorticoid signaling pathway

ARID1A PHB1 CRY1

1.08e-04171153GO:0042921
GeneOntologyBiologicalProcessbranching morphogenesis of an epithelial tube

NCOA3 MAGED1 PLXND1 CELSR1 PKHD1 DCHS1 NOTCH4

1.23e-041981157GO:0048754
GeneOntologyBiologicalProcessnuclear receptor-mediated corticosteroid signaling pathway

ARID1A PHB1 CRY1

1.30e-04181153GO:0031958
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

NCOA3 MAGED1 FRS2 PLXND1 RUNX3 ARID1A CELSR1 SULF1 PKHD1 DCHS1 PCDH8 NOTCH4

1.77e-0461911512GO:0002009
DomainACTINS_1

ACTA1 ACTA2 ACTC1

1.28e-0581163PS00406
DomainIGv

HSPG2 OBSCN BTN2A2 ROBO2 IGSF9B

1.03e-04751165SM00406
DomainActin_CS

ACTA1 ACTA2 ACTC1

1.23e-04161163IPR004001
DomainACTINS_2

ACTA1 ACTA2 ACTC1

1.49e-04171163PS00432
DomainActin/actin-like_CS

ACTA1 ACTA2 ACTC1

1.78e-04181163IPR020902
DomainACTINS_ACT_LIKE

ACTA1 ACTA2 ACTC1

2.10e-04191163PS01132
PathwayPID_CASPASE_PATHWAY

TRAF2 ACTA1 PIDD1 MADD PRF1

1.42e-0551865M220
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

ATG16L1 TBC1D30 HACD3 TAS1R3 OBSCN FRS2 PIDD1 ARHGAP9 LRRC70 DIP2A URB1 MYO15B MDN1 PKHD1 MAP3K9 IGSF9B

4.33e-097361181629676528
Pubmed

Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.

ACTA1 ACTA2 ACTC1

3.81e-08311837780165
Pubmed

FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.

ACTA1 ACTA2 FRS2 ACTC1

4.08e-0811118422207710
Pubmed

Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.

ACTA1 ACTA2 ACTC1

7.56e-07611839971772
Pubmed

Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.

ACTA1 ACTA2 ACTC1

7.56e-076118310074138
Pubmed

Virus assembly and plasma membrane domains: which came first?

ACTA1 ACTA2 ACTC1

7.56e-076118322989508
Pubmed

HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.

ACTA1 ACTA2 ACTC1

7.56e-07611831540415
Pubmed

HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.

ACTA1 ACTA2 ACTC1

7.56e-076118311709093
Pubmed

Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.

ACTA1 ACTA2 ACTC1

7.56e-076118310049817
Pubmed

Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.

ACTA1 ACTA2 ACTC1

7.56e-076118312009869
Pubmed

HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.

ACTA1 ACTA2 ACTC1

7.56e-076118323811015
Pubmed

Retroviral assembly and budding occur through an actin-driven mechanism.

ACTA1 ACTA2 ACTC1

7.56e-076118319883584
Pubmed

Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.

ACTA1 ACTA2 ACTC1

7.56e-076118321917091
Pubmed

HIV-1 Gag protein associates with F-actin present in microfilaments.

ACTA1 ACTA2 ACTC1

7.56e-07611838661406
Pubmed

A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.

ACTA1 ACTA2 ACTC1

7.56e-076118323017337
Pubmed

Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.

ACTA1 ACTA2 ACTC1

7.56e-076118323875777
Pubmed

Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.

ACTA1 ACTA2 ACTC1

7.56e-07611839841925
Pubmed

Essential and supporting host cell factors for HIV-1 budding.

ACTA1 ACTA2 ACTC1 AP1M1

1.06e-0623118422004035
Pubmed

The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.

ACTA1 ACTA2 ACTC1

1.32e-067118322535526
Pubmed

Selective targeting of ITK blocks multiple steps of HIV replication.

ACTA1 ACTA2 ACTC1

1.32e-067118318443296
Pubmed

The trinity of the cortical actin in the initiation of HIV-1 infection.

ACTA1 ACTA2 ACTC1

1.32e-067118322640593
Pubmed

HIV-1 replication from after cell entry to the nuclear periphery.

ACTA1 ACTA2 ACTC1

1.32e-067118317504171
Pubmed

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

ACTA1 ACTA2 ACTC1

1.32e-067118322465675
Pubmed

Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.

ACTA1 ACTA2 ACTC1

1.32e-06711839384381
Pubmed

A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.

ACTA1 ACTA2 ACTC1

1.32e-067118330289203
Pubmed

Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.

ACTA1 ACTA2 ACTC1

2.11e-068118320096780
Pubmed

Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.

ACTA1 ACTA2 ACTC1

2.11e-068118314694110
Pubmed

Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.

ACTA1 ACTA2 ACTC1

2.11e-068118320147394
Pubmed

Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.

ACTA1 ACTA2 ACTC1

2.11e-068118323260110
Pubmed

Defining the membrane proteome of NK cells.

CALCOCO2 AMFR ACTC1 CC2D1A PIGG PTBP1 ANKRD27 PHB1 MDN1 PRF1 CHTF18 AP1M1 KIF2A NONO SLC33A1 ALG12

2.21e-0611681181619946888
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

TNIK ELOB MAGED1 HACD3 ARGLU1 FRS2 CC2D1A SPICE1 PHB1 PNPT1 DIP2A URB1 COCH MDN1 DLAT SENP2 SLC33A1 ATP6V0A2

2.78e-0614871181833957083
Pubmed

Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.

ACTA1 ACTA2 ACTC1

3.15e-069118310556093
Pubmed

Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.

ACTA1 ACTA2 ACTC1

3.15e-069118312297046
Pubmed

Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.

ACTA1 ACTA2 ACTC1

3.15e-06911838892894
Pubmed

HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.

ACTA1 ACTA2 ACTC1

3.15e-069118318775311
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ENTPD7 HSPG2 HACD3 SPTLC2 MATN2 PIGG PLXND1 ECI1 MADD CELSR1 COCH ENTPD6 KIF2A SLC33A1 ALG12 ATP6V0A2

3.16e-0612011181635696571
Pubmed

Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization.

ACTA1 ACTC1 PTBP1 NONO

4.21e-0632118436252997
Pubmed

Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.

ACTA1 ACTA2 ACTC1

4.49e-061011831907279
Pubmed

Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.

ACTA1 ACTA2 ACTC1

4.49e-0610118321749862
Pubmed

Non-viral cellular substrates for human immunodeficiency virus type 1 protease.

ACTA1 ACTA2 ACTC1

4.49e-061011831991513
Pubmed

Gelsolin activity controls efficient early HIV-1 infection.

ACTA1 ACTA2 ACTC1

4.49e-0610118323575248
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 HSPG2 OBSCN CC2D1A PIGG PLXND1 ARID1A MADD DIP2A BMP8B URB1 CELSR1 MDN1 PIK3C2B SENP2

5.27e-0611051181535748872
Pubmed

CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.

ACTA1 ACTA2 ACTC1

6.16e-0611118330962377
Pubmed

N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.

ACTA1 ACTA2 ACTC1

6.16e-0611118323294842
Pubmed

Quantitative proteomic analysis of lentiviral vectors using 2-DE.

ACTA1 ACTA2 ACTC1

6.16e-0611118319639585
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

HACD3 ACTA1 PTBP1 PHB1 URB1 MDN1 DLAT PALS2 NONO ATP6V0A2

6.34e-064841181031995728
Pubmed

SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.

ACTA1 ACTA2 ACTC1

8.19e-0612118331042497
Pubmed

HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.

ACTA1 ACTA2 ACTC1

8.19e-0612118323071112
Pubmed

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.

ACTA1 ACTA2 ACTC1

1.06e-0513118318400219
Pubmed

Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.

ACTA1 ACTC1

1.14e-052118220706863
Pubmed

Bone morphogenetic protein 8A plays a role in the maintenance of spermatogenesis and the integrity of the epididymis.

BMP8B BMP8A

1.14e-05211829463357
Pubmed

The gene encoding bone morphogenetic protein 8B is required for the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

1.14e-05211828682296
Pubmed

A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.

ACTA1 ACTC1

1.14e-05211823023046
Pubmed

The protective role of bone morphogenetic protein-8 in the glucocorticoid-induced apoptosis on bone cells.

BMP8B BMP8A

1.14e-052118221277400
Pubmed

Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.

ACTA1 ACTC1

1.14e-05211823075543
Pubmed

Human BMP8A suppresses luteinization of rat granulosa cells via the SMAD1/5/8 pathway.

BMP8B BMP8A

1.14e-052118231940275
Pubmed

Hyperplastic conotruncal endocardial cushions and transposition of great arteries in perlecan-null mice.

HSPG2 ACTA2

1.14e-052118212142349
Pubmed

Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.

ACTA1 ACTC1

1.14e-052118219468071
Pubmed

alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.

ACTA1 ACTC1

1.14e-05211821893870
Pubmed

Rasd1 modulates the coactivator function of NonO in the cyclic AMP pathway.

RASD1 NONO

1.14e-052118221915321
Pubmed

Heterodimerization of Chemoreceptors TAS1R3 and mGlu2 in Human Blood Leukocytes.

TAS1R3 GRM2

1.14e-052118237629122
Pubmed

Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.

ACTA2 ACTC1

1.14e-052118210686609
Pubmed

PTPLAD1 Regulates PHB-Raf Interaction to Orchestrate Epithelial-Mesenchymal and Mitofusion-Fission Transitions in Colorectal Cancer.

HACD3 PHB1

1.14e-052118238617530
Pubmed

A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.

ACTA1 ACTC1

1.14e-05211822731651
Pubmed

A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.

ACTA1 ACTC1

1.14e-05211826897014
Pubmed

LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.

ACTA1 ACTA2 ACTC1

1.35e-0514118321923909
Pubmed

Regulating the functions of the HIV-1 matrix protein.

ACTA1 ACTA2 ACTC1

1.35e-0514118317411366
Pubmed

Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.

ACTA1 ACTA2 ACTC1

1.68e-0515118324598388
Pubmed

Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.

ACTA1 ACTA2 OBSCN ECI1 PHB1 FSIP2 PNPT1 DLAT

1.83e-05331118829199018
Pubmed

Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.

ACTA1 ACTA2 ACTC1

2.06e-0516118316638982
Pubmed

Serum response factor is essential for mesoderm formation during mouse embryogenesis.

ACTA1 ACTA2 ACTC1

2.06e-051611839799237
Pubmed

Global comparative transcriptome analysis of cartilage formation in vivo.

BMP8B BMP8A PCDH8

2.06e-0516118319272164
Pubmed

TAB2 and TAB3 activate the NF-kappaB pathway through binding to polyubiquitin chains.

AMFR TRAF2 TANK

2.06e-0516118315327770
Pubmed

Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.

ACTA1 ACTA2 ACTC1

2.50e-0517118317360745
Pubmed

The cleavage of host cell proteins by HIV-1 protease.

ACTA1 ACTA2 ACTC1

2.50e-051711838997639
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SGIP1 HACD3 ARGLU1 ACTA1 PTBP1 ECI1 GRM2 ARID1A MADD DIP2A NWD2 LMO7 CRACDL MAST1 DLAT KIF2A

2.77e-0514311181637142655
Pubmed

A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.

ACTA1 ACTA2 ACTC1

2.99e-0518118324840128
Pubmed

Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.

ACTA1 ACTA2 ACTC1

2.99e-0518118315929941
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

TRAF2 SMC6 MDN1 LMO7 CHTF18 DLAT SENP2

3.29e-05262118736880596
Pubmed

Evidence that Mothers-against-dpp-related 1 (Madr1) plays a role in the initiation and maintenance of spermatogenesis in the mouse.

BMP8B BMP8A

3.42e-05311829076678
Pubmed

Evaluating the association between pathological myopia and SNPs in RASGRF1. ACTC1 and GJD2 genes at chromosome 15q14 and 15q25 in a Chinese population.

GJD2 ACTC1

3.42e-053118223834555
Pubmed

Mouse ganglion-cell photoreceptors are driven by the most sensitive rod pathway and by both types of cones.

GJD2 CRY1

3.42e-053118223762490
Pubmed

LRDD, a novel leucine rich repeat and death domain containing protein.

PIDD1 MADD

3.42e-053118210825539
Pubmed

Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.

ACTA1 ACTC1

3.42e-05311821728592
Pubmed

Requirement of Bmp8b for the generation of primordial germ cells in the mouse.

BMP8B BMP8A

3.42e-053118210894154
Pubmed

The human beta-actin multigene family.

ACTA1 ACTA2

3.42e-05311823842206
Pubmed

BMP8B increases brown adipose tissue thermogenesis through both central and peripheral actions.

BMP8B BMP8A

3.42e-053118222579288
Pubmed

The role of different Scinderin domains in the control of F-actin cytoskeleton during exocytosis.

ACTA1 ACTC1

3.42e-053118212438125
Pubmed

Mutation in Bmp7 exacerbates the phenotype of Bmp8a mutants in spermatogenesis and epididymis.

BMP8B BMP8A

3.42e-053118211784057
Pubmed

The genes coding for the cardiac muscle actin, the skeletal muscle actin and the cytoplasmic beta-actin are located on three different mouse chromosomes.

ACTA1 ACTC1

3.42e-05311826641707
Pubmed

Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a.

BMP8B BMP8A

3.42e-053118225451979
Pubmed

Genetic variants and clinical relevance associated with gestational diabetes mellitus in Chinese women: a case-control study.

PLXND1 NFE2L3

3.42e-053118228554271
Pubmed

Calcium wave dynamics in the embryonic mouse gut mesenchyme: impact on smooth muscle differentiation.

CACNA1C ACTA2

3.42e-053118239375515
Pubmed

Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT.

ACTA1 ACTC1

3.42e-053118222647617
Pubmed

Osteogenic activity of the fourteen types of human bone morphogenetic proteins (BMPs).

BMP8B BMP8A

3.42e-053118212925636
Pubmed

Lineage tree for the venous pole of the heart: clonal analysis clarifies controversial genealogy based on genetic tracing.

ACTA1 ACTC1

3.42e-053118222855565
Pubmed

NF-kappaB activation through IKK-i-dependent I-TRAF/TANK phosphorylation.

TRAF2 TANK

3.42e-053118210759890
Pubmed

Crystal structure of the complex between actin and human vitamin D-binding protein at 2.5 A resolution.

ACTA1 ACTA2

3.42e-053118212119014
Pubmed

Down-regulation of a novel actin-binding molecule, skeletrophin, in malignant melanoma.

ACTA1 ACTC1

3.42e-053118214507647
Pubmed

Actin-DBP: the perfect structural fit?

ACTA1 ACTC1

3.42e-053118212554937
GeneFamilyActins

ACTA1 ACTA2 ACTC1

1.30e-066743929
GeneFamilyFibronectin type III domain containing

OBSCN SNED1 CSF2RB ROBO2 IGSF9B

5.02e-04160745555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

HSPG2 OBSCN HEPACAM2 ROBO2 IGSF9B

5.17e-04161745593
GeneFamilyBone morphogenetic proteins|Astacins

BMP8B BMP8A

8.87e-0411742455
GeneFamilyAT-rich interaction domain containing

ARID1A ARID3B

1.68e-0315742418
GeneFamilyPDZ domain containing

RHPN2 LMO7 MAST1 PALS2

3.50e-031527441220
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

CACNA1C ACTA2 PLXND1 SULF1 DCHS1 BMP8A NEURL1B

6.60e-0718611871e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)|343B / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 DCHS1 NOTCH4

7.88e-07191118727a532a35d9e8822014f581fd56c4ca62e39f8fe
ToppCell343B-Endothelial_cells-Endothelial-B_(Artery)-|343B / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 DCHS1 NOTCH4

7.88e-0719111871dfcff08e01e6a695953334342bcfde04ba005ad
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TNIK TRAF2 PGGHG RUNX3 SULF1 PRF1

3.92e-061571186a633fb8e7a009490c6002bf272eceaf317f27af6
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HEPACAM2 RUNX3 CHTF18 RECQL5 NEURL1B ALG12

4.86e-0616311867af3d3ae7e0de733a18d0486c7ffbb5a7ef7230a
ToppCellIonocyte-iono-1|World / Class top

ELOB HACD3 HEPACAM2 PIGG COCH RASD1

5.98e-0616911864b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 MATN2 PIK3C2B DCHS1 NEURL1B NOTCH4

6.61e-061721186a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

ENTPD7 NCOA3 DCDC2B PNPT1 URB1 IGSF9B

7.54e-0617611863de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

ENTPD7 NCOA3 DCDC2B PNPT1 URB1 IGSF9B

7.79e-06177118682fdd6185b368f54f03de389427cbe3071d21a99
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTC1 ARHGAP9 HEPACAM2 RUNX3 ATP6V0A2 FAM149A

8.05e-061781186ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTC1 ARHGAP9 HEPACAM2 RUNX3 ATP6V0A2 FAM149A

8.05e-0617811866c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTC1 ARHGAP9 HEPACAM2 RUNX3 ATP6V0A2 FAM149A

8.05e-061781186cd85dcefe94ee742db64b63e105e13532321894a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 PLXND1 PIK3C2B DCHS1 NEURL1B NOTCH4

8.31e-0617911868f9e538c822940785130297712b75131812a4603
ToppCellControl-Myeloid-DC1|Control / Condition, Lineage and Cell class

HSPG2 RDH5 RUNX3 NPFFR1 FSIP2 FAM149A

8.85e-0618111865a2a1f017ad23baed9972c68b4a46f4c618ef21a
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

TNIK CACNA1C ACTA1 OBSCN ACTC1 LMO7

9.13e-061821186287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellControl-Myeloid-DC1|Myeloid / Condition, Lineage and Cell class

HSPG2 RDH5 RUNX3 NPFFR1 FSIP2 FAM149A

9.72e-061841186b5c1f57f0356969cfb0e1dac764684fc5583bc04
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 PLXND1 COCH RHPN2 LMO7 SULF1

1.03e-0518611861e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCelldroplet-Pancreas|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 GJD2 MAGED1 HEPACAM2 ROBO2 CPEB1

1.07e-0518711865f4df092452d8672bda4059c794e099ba3f5a8fa
ToppCellCOVID-19-kidney-AQP1+SLC14A1+EC|kidney / Disease (COVID-19 only), tissue and cell type

HSPG2 ARGLU1 PLXND1 PIK3C2B SULF1 NOTCH4

1.17e-0519011861519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 SNED1 COCH SULF1 DCHS1 IGSF9B

1.17e-0519011863cf464664d6aa22b212e60b70885953887e92483
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C SGIP1 ACTA2 RDH5 MUC5B RASD1

1.17e-0519011861ab3f19f1ce9f58e5125135704d94655a2e330a0
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 NOTCH4

1.20e-05191118650601ef0a5a8f2c2120922989e08e85bf2d9b4ab
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GJD2 MAGED1 ARGLU1 HEPACAM2 MADD RASD1

1.24e-0519211861304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCellPCW_05-06-Epithelial-Epithelial_neuroendo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

VWA5B2 HEPACAM2 CELSR1 LMO7 PKHD1 FAM149A

1.27e-051931186aa10924b203c71e65fdbd2b90ba131dbd362d8b1
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C HSPG2 PLXND1 SNED1 NEURL1B NOTCH4

1.35e-051951186a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C SGIP1 ACTA2 ACTC1 SULF1 NEURL1B

1.43e-051971186cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellcellseq-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-AEC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 NOTCH4

1.43e-05197118656afed433887cb2766eb30f22aec195148db33ab
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C HSPG2 ARGLU1 PIK3C2B NEURL1B NOTCH4

1.47e-0519811868689090bce9ab6e8f122426a404037e572c6713b
ToppCelldistal-3-Endothelial-Artery|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 NOTCH4

1.52e-0519911867814804f4ecc0655610e5c85f513b3976d856192
ToppCelldistal-Endothelial-Artery|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 NOTCH4

1.52e-051991186b6e9aaac047d4b64b9d97f5e174e89a424d8b36d
ToppCelldistal-Endothelial-Artery-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 ARGLU1 MATN2 PIK3C2B SULF1 NOTCH4

1.52e-0519911863788f3218356aaaa10684e48d63757037f8a3a3c
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 MATN2 PIK3C2B SULF1 DCHS1 NOTCH4

1.56e-052001186ac6b8bc9998d303f788511b8f111e682ea9f3df8
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C SGIP1 ACTA2 ACTC1 SULF1 IGSF9B

1.56e-052001186a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 PLXND1 SNED1 DCHS1 NEURL1B NOTCH4

1.56e-052001186b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCellTracheal-NucSeq-Epithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TBC1D30 MUC5B CELSR1 RHPN2 LMO7 CRACDL

1.56e-052001186d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CACNA1C HSPG2 LRRC70 SULF1 CPEB1

2.61e-051311185ff4e618bd944f852bbd34438f740187aca82460f
ToppCellPND07-28-samps-Lymphocyte-B_cell-B_cell_2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TAS1R3 RUNX3 PIK3C2B ENTPD6 FCRL5

3.23e-0513711852544d1256f11da6e3bad24a871b2253e0ab20d01
ToppCellPND07-28-samps-Lymphocyte-B_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

TAS1R3 RUNX3 PIK3C2B ENTPD6 FCRL5

3.23e-051371185874e2eaa7846a2832f46b77c726d79f220a4a1cd
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

AMFR DNAAF4 SNED1 CHTF18 CPXM1

3.83e-0514211856a656d28c9f5dfb03a3a2d908cf2edbe0a5b1206
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

AMFR DNAAF4 SNED1 CHTF18 CPXM1

3.83e-051421185671ba8869db7a6dc69fd1caf0e561f15a312b170
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

AMFR DNAAF4 SNED1 CHTF18 CPXM1

3.83e-0514211853557084150670fd2e2634fc674f228ab85181b59
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Alcam_(Alcam)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

AMFR DNAAF4 SNED1 CHTF18 CPXM1

3.83e-051421185a3d1f4b570b75402171e38c5a7c88e2896520c8f
ToppCelltumor_Lung-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

OBSCN LIPE PIK3C2B PRF1 CPXM1

4.38e-0514611858b2d104fdb0fdb09410450c6c651e1edb00cae44
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

ACTA2 DCDC2B DGAT2L6 FSIP2 RASD1

4.52e-05147118527e97a7b1dc296f52990b5810a52ab0a7ef2b9e6
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C TRAF2 SGIP1 ACTA2 ROBO2

4.67e-05148118581a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellIIH-CD4-CD4_Treg|IIH / Condition, Cell_class and T cell subcluster

SPICE1 SNED1 CELSR1 IGSF9B ATP6V0A2

5.47e-05153118528fb5d9f66f58741a5d43df004f80da3d910682e
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACTA2 CC2D1A MDN1 DCHS1 ALG12

5.64e-05154118516fdafb5c64d2db321554f87129a962d113f1668
ToppCelldroplet-Lung-nan-3m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEPACAM2 PIK3C2B MAST1 FCRL5 XKRX

6.37e-05158118566c011e9de002224f70725dfe8e7871c8d304492
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRY1 AGXT2 TMEM37 IGSF9B BMP8A

6.56e-051591185709b57f992a29878cc899d760d144d36cb5cb280
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C HSPG2 GJD2 PLXND1 NOTCH4

6.76e-0516011850d4880f85565d8c540c94a8f8109147b3029279a
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNIK TAS1R3 RUNX3 PRF1 TMEM37

6.76e-0516011856b0faaa371650563f585722f5b2fb319e124ec38
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN MADD URB1 QTRT1 XKRX

6.96e-051611185ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCelldroplet-Thymus-nan-21m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 OBSCN CSF2RB SULF1 FAM149A

6.96e-051611185441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HEPACAM2 PIK3C2B MAST1 FCRL5 XKRX

6.96e-0516111857af3b0d4fc7967f6b3e2d255d23fd8b1fd01a7af
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENTPD7 MUC5B HEPACAM2 MAP3K9 ROBO2

6.96e-0516111857c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D30 DNAAF4 HEPACAM2 MDN1 FCRL5

6.96e-051611185249c2b97cc25de5053f5048ee354615df49b2081
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN MADD URB1 QTRT1 XKRX

6.96e-0516111850089d7bb305c592392791862a3341fc92af8f3e2
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-Zbtb32+_B_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HEPACAM2 PIK3C2B MAST1 FCRL5 XKRX

6.96e-05161118598be0cf8228496b31f7f3e0efd8787e95eb626d1
ToppCelldroplet-Marrow-nan-21m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEPACAM2 CELSR1 LMO7 RASD1 BCAR3

7.17e-051621185d0ffebf5adee8a3ac9b81a4b793184f54010489a
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PIDD1 ARHGAP9 RUNX3 PRF1 CHTF18

7.38e-0516311859c91415a56b12b3b2d15d253bb59db8bedf49ea2
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM2 AGXT2 CRACDL IGSF9B NEURL1B

7.60e-051641185b895674ed2df87db8fbfb30b7e31620945588491
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D30 ACTC1 SNED1 MAST1 FCRL5

8.05e-05166118591eeb48680dd07ae4115afacdc0a8f6fa18885e5
ToppCelldroplet-Bladder-nan-3m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARHGAP9 HEPACAM2 RUNX3 CSF2RB FCRL5

8.05e-051661185e01c720de6d4ca144c55378e023e718a64bf32f6
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-|GI_small-bowel / Manually curated celltypes from each tissue

ARHGAP9 PLXND1 PRF1 CPXM1 BMP8A

8.28e-0516711857ff186b2bed3b0de93addb3b0ae5a2c6e44ddfb2
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLXND1 GRM2 COCH CRACDL IGSF9B

8.28e-051671185f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN NPFFR1 CELSR1 COCH SULF1

8.28e-051671185a4a795751644b22af616335379e64ae95175180c
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

HSPG2 CSF2RB RECQL5 RASD1 NOTCH4

8.51e-051681185dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellmild_COVID-19-HSPC|mild_COVID-19 / disease group, cell group and cell class (v2)

CACNA1C HSPG2 SGIP1 CPXM1 CPEB1

8.51e-05168118590b33962adb77d8326dee403712118398b4d1315
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 MATN2 NFE2L3 PIK3C2B NOTCH4

8.75e-051691185605cc2638271803cf1d972ab3fa8f13f89666376
ToppCell356C-Endothelial_cells-Endothelial-B_(Artery)-|356C / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 MATN2 NFE2L3 PIK3C2B NOTCH4

8.75e-051691185337be3bf485b54afad86e256cb0c4c1d0c2a9a2a
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

DNAAF4 SPICE1 FSIP2 URB1 PRF1

8.75e-051691185bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRAF2 SMC6 RUNX3 PIK3C2B PRF1

9.00e-05170118528fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PGGHG SPTLC2 FSIP2 PKHD1 PALS2

9.00e-0517011855d5f208682be21ed58320f5fc083a7898f8712da
ToppCellIonocyte|World / Class top

ELOB HACD3 HEPACAM2 COCH RASD1

9.00e-051701185d2e592f2a679e6a8d32f2b752d9a3c493e50ced4
ToppCellmild_COVID-19-HSPC|World / disease group, cell group and cell class (v2)

CACNA1C HSPG2 SGIP1 CPXM1 CPEB1

9.00e-05170118585c476e0bc496445e868a88849960598d97bdea2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRAF2 SMC6 RUNX3 PIK3C2B PRF1

9.00e-051701185239cb4b801b2d71a6facb386f2684c0851504151
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C HSPG2 SMC6 NWD2 NEURL1B

9.00e-0517011855570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C SGIP1 ACTA2 RASD1 NEURL1B

9.25e-051711185b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellNS-critical-d_0-4-Lymphoid-B_cell|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FSIP2 URB1 LIPE FCRL5 PALS2

9.25e-051711185bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C SGIP1 ACTA2 RASD1 NEURL1B

9.25e-0517111859d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TNIK RUNX3 DIP2A PRF1 CELF2-AS1

9.25e-051711185adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|367C / Donor, Lineage, Cell class and subclass (all cells)

RUNX3 BMP8B PRF1 CHTF18 MAP3K9

9.25e-0517111854ede6e916e593f208f2f8ccf82ef2335e061fc86
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RUNX3 NFE2L3 SESN2 XKRX

9.51e-05172118524ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 ARHGAP9 RUNX3 ARID3B CSF2RB

9.51e-05172118572fbfa890995e47048b47199c170cc7dcd7661f8
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM2 ARHGAP9 RUNX3 ARID3B CSF2RB

9.51e-0517211852ca6f0d1181aabe0d0e3e8f2e193f08dbda42dea
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN RUNX3 NFE2L3 SESN2 XKRX

9.51e-051721185db5a31cafce4346fe459d7f35210823fd7004439
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 MYO15B LMO7 TMEM37 MAP3K9

9.77e-05173118545808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCell367C-Myeloid-Dendritic-cDC_activated|367C / Donor, Lineage, Cell class and subclass (all cells)

ENTPD7 TRAF2 BTN2A2 CSF2RB KIF2A

9.77e-05173118594f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CELSR1 MYO15B LMO7 TMEM37 MAP3K9

9.77e-0517311857fa9dbcb258c3ab974490063951620e2def03db1
ToppCellIonocyte-iono-2|World / Class top

ACTA1 HEPACAM2 COCH RASD1 NEURL1B

9.77e-051731185e5ec28ccc5e048fd98de4c876e5c53b866b66228
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

AMFR OBSCN FRS2 ECI1 ATP6V0A2

9.77e-0517311854f2843371d18af766c1892529ce286f56c956fde
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Zbtb32+_B|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEPACAM2 PIK3C2B SESN2 FCRL5 XKRX

1.00e-04174118528ec25767bbd4fd898738f9f4d2b585dc91b5adf
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

HSPG2 ARGLU1 GRM2 PIK3C2B NOTCH4

1.00e-04174118518ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

NCOA3 TAS1R3 FCRL5 BCAR3 PALS2

1.00e-041741185ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

ENTPD7 TRPM2 ARID3B RASD1 NOTCH4

1.00e-041741185be8227398300711ccda5ecc41ad34064bb246b19
ToppCellAdult-Endothelial-endothelial_cell_of_artery-D175|Adult / Lineage, Cell type, age group and donor

MATN2 PIK3C2B SULF1 DCHS1 NOTCH4

1.03e-0417511850a65ddfa8c2e8efb5b5338cf07661cb78157a23c
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Lymphocytic-T_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TBC1D30 RUNX3 MADD CELSR1 PRF1

1.09e-0417711859d2d70d53b919fed3328812889a55e5e1a0759de
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIDD1 HEPACAM2 PIK3C2B FCRL5 XKRX

1.09e-041771185a58c93be9767e3fe8fbb6b0db1210d3a33aac662
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIDD1 HEPACAM2 PIK3C2B FCRL5 XKRX

1.09e-0417711853ed383e5c0b15d9d5e75b98cf6d10609f48fc422
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

ENTPD7 TRPM2 ARID3B RASD1 NOTCH4

1.09e-041771185415aa023195a7f961c09529f65cdcc7bb90eaf5d
DiseaseMoyamoya disease (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

2.86e-0681113DOID:13099 (implicated_via_orthology)
Diseaseautosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

2.86e-0681113DOID:0110550 (implicated_via_orthology)
DiseaseBaraitser-Winter syndrome 1 (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

2.86e-0681113DOID:0081112 (implicated_via_orthology)
Diseasethoracic aortic aneurysm (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

2.86e-0681113DOID:14004 (implicated_via_orthology)
Diseaseintestinal atresia (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

6.10e-06101113DOID:10486 (implicated_via_orthology)
Diseasepatent ductus arteriosus (implicated_via_orthology)

ACTA1 ACTA2 ACTC1

6.10e-06101113DOID:13832 (implicated_via_orthology)
DiseaseMalignant neoplasm of breast

NCOA3 AMFR TANK ACTA2 SMC6 OBSCN HEPACAM2 ARID1A PHB1 LIPE AP1M1 FCRL5 BCAR3 PCDH8 NOTCH4

1.23e-05107411115C0006142
DiseaseRefractive Errors

GJD2 ACTC1

4.20e-0531112C0034951
DiseaseAmetropia

GJD2 ACTC1

4.20e-0531112C1527310
DiseaseHypertrophic Cardiomyopathy

CACNA1C ACTA1 OBSCN ACTC1

6.42e-05571114C0007194
Diseaseasthma (implicated_via_orthology)

RUNX3 CSF2RB PRF1

3.11e-04351113DOID:2841 (implicated_via_orthology)
Diseaseaortic dissection (is_marker_for)

ACTA1 NONO

3.87e-0481112DOID:0080685 (is_marker_for)
DiseasePsychotic Disorders

CACNA1C TRPM2 CSF2RB NPAS1

5.85e-041011114C0033975
Diseaseeye disease

GJD2 RDH5 PNPT1

6.55e-04451113EFO_0003966
Diseaselymphocyte:monocyte ratio

TRAF2 TANK PRF1 AP1M1 BCAR3 NEURL1B

7.89e-042881116EFO_0600088
DiseaseCarcinoma, Granular Cell

NCOA3 RUNX3 ARID1A PHB1

9.82e-041161114C0205644
DiseaseAdenocarcinoma, Tubular

NCOA3 RUNX3 ARID1A PHB1

9.82e-041161114C0205645
DiseaseAdenocarcinoma, Oxyphilic

NCOA3 RUNX3 ARID1A PHB1

9.82e-041161114C0205642
DiseaseCarcinoma, Cribriform

NCOA3 RUNX3 ARID1A PHB1

9.82e-041161114C0205643
DiseaseAdenocarcinoma, Basal Cell

NCOA3 RUNX3 ARID1A PHB1

9.82e-041161114C0205641
DiseaseAdenocarcinoma

NCOA3 RUNX3 ARID1A PHB1

9.82e-041161114C0001418
Diseasesugar consumption measurement

TANK CRACDL PKHD1 IGSF9B

1.11e-031201114EFO_0010158
DiseaseMetastatic melanoma

TTBK1 MAP3K9 MAST1

1.12e-03541113C0278883
Diseaseobesity (implicated_via_orthology)

PLXND1 BMP8B DCHS1 BMP8A NOTCH4

1.34e-032151115DOID:9970 (implicated_via_orthology)
DiseaseColorectal Carcinoma

CALCOCO2 OBSCN ARID1A RHPN2 LMO7 PKHD1 DCHS1 SESN2 SLC33A1

1.36e-037021119C0009402
Diseaselateral ventricle volume change measurement

NFE2L3 FAM149A

1.43e-03151112EFO_0021502
DiseaseMyopia

GJD2 RDH5

1.43e-03151112C0027092
DiseasePsychoses, Substance-Induced

GRM2 PHB1

1.84e-03171112C0033941
Diseasechronotype measurement

CALCOCO2 SGIP1 ARHGAP9 MADD CRY1 SULF1 PKHD1 DCHS1 RASD1 ROBO2

1.84e-0388211110EFO_0008328
DiseaseNonorganic psychosis

CACNA1C TRPM2 NPAS1

2.27e-03691113C0349204
Diseaseanorectal malformation

TRPM2 MUC5B

2.30e-03191112MONDO_0019938
Diseasenephrotic syndrome

RUNX3 NWD2 COCH

2.46e-03711113EFO_0004255
DiseasePsychoses, Drug

GRM2 PHB1

2.81e-03211112C0033937
Diseasetransient cerebral ischemia (biomarker_via_orthology)

MBD1 TRPM2 MADD ROBO2

2.97e-031571114DOID:224 (biomarker_via_orthology)
DiseaseIntrahepatic Cholangiocarcinoma

ARID1A ROBO2

3.67e-03241112C0345905
DiseaseExtrahepatic Cholangiocarcinoma

ARID1A ROBO2

3.67e-03241112C3805278

Protein segments in the cluster

PeptideGeneStartEntry
RFQPQPRGIVTLSDF

SLC33A1

246

O00400
VGRGSIFSQTFRIAP

AGXT2

471

Q9BYV1
RVPPTAAVAQVFERG

ARID3B

71

Q8IVW6
FFGRVVVRSTAVPSA

CHTF18

916

Q8WVB6
DLPRVSVPNFGRTQS

GJD2

301

Q9UKL4
RFRCPETLFQPSFIG

ACTA1

256

P68133
FRTGSEPALSPAVVR

BCAR3

366

O75815
VARRNPFVFAPTLLT

AFM

166

P43652
NIFGRRSVSSFPVPQ

ATG16L1

281

Q676U5
SSPPDRIDIFGRTVS

ARGLU1

76

Q9NWB6
EGAQRPRFISPASQV

GRM2

666

Q14416
RFRCPETLFQPSFIG

ACTA2

256

P62736
RFENDRTISFIPPDG

AP1M1

246

Q9BXS5
VTRNCRVTFEEGPFP

CPXM1

681

Q96SM3
SFPPQSFVTFRGLRQ

CELSR1

1446

Q9NYQ6
PLGQRQPRRSFFESF

TMEM37

11

Q8WXS4
RTFLGPVVIAVFSSP

ALG12

66

Q9BV10
PAGRSVRVFISANPE

NWD2

36

Q9ULI1
NRPGFVTVTRPRAEN

MUC5B

5461

Q9HC84
FRPVASQLPRIFTSI

PHB1

96

P35232
PQRNSRLTGEFTVEP

HSPG2

1361

P98160
DAFGIVAPFARRPSV

RASD1

241

Q9Y272
VPPSSLVQERSFFVR

NPAS1

236

Q99742
RRDITFPPGSVEATQ

ARID1A

1636

O14497
GRLNDPSVVTPFSRD

ANKRD27

446

Q96NW4
RVFVVVRPSDSGLPS

NPFFR1

371

Q9GZQ6
ALPGSFVVRVTARDP

DCHS1

486

Q96JQ0
PRSFLNRFTQVFVDP

MDN1

1881

Q9NU22
GSFLLTTFPRPVTVE

NONO

211

Q15233
FTQGEGARPLSTRVP

MATN2

746

O00339
GSFLASRPRQTPFAE

MADD

526

Q8WXG6
NARSRFPQTFAGPII

MAGED1

741

Q9Y5V3
FTVPTVSPFLRQRVA

ENTPD7

16

Q9NQZ7
IPIFNETGRFSFTLP

HACD3

301

Q9P035
SRFPPLVTETRGQNT

FAM149A

656

A5PLN7
PRLGFSRVPDTQVAF

CELF2-AS1

141

Q8N7Q2
PTRNFSRVSQAFLDP

FSIP2

431

Q5CZC0
PVITEIFSLGGTRFR

MBD1

571

Q9UIS9
ERLFAVFERPQGSPA

PLXND1

366

Q9Y4D7
QEPFTRPVLRASSFQ

FCRL5

186

Q96RD9
PTGVFTDIPISNIRR

DLAT

416

P10515
VVFAFGARTPPEARR

PCDH8

281

O95206
SGSFPVDTQRFLRPD

PRF1

56

P14222
RALGVPFVPRTSVDA

NFE2L3

96

Q9Y4A8
VRLTSVVTPRPFGSQ

LMO7

906

Q8WWI1
VVTPRPFGSQTRGIS

LMO7

911

Q8WWI1
FPGRTFSDVRDPLQS

PGGHG

701

Q32M88
IFIPESGQDATRPVR

CRACDL

96

Q6NV74
ERIPTSPAGRFFQEN

LRRC70

456

Q7Z2Q7
TTPFENTSIRIGPAR

MAST1

1051

Q9Y2H9
PSFPSRFVIGRSRGE

PIK3C2B

1426

O00750
PVTFPTARLRVFVRN

OBSCN

7936

Q5VST9
VGTRSANFPVRVPFE

MYO15B

261

Q96JP2
RVVGSARARPSQFPE

KIF2A

111

O00139
FGTTVPFTSRKPRED

PALS2

366

Q9NZW5
FRGVILTSDRPGVFS

ECI1

91

P42126
FSFQPDRPLGTRLTV

CSF2RB

111

P32927
DGRSAFPQTFTTQRP

CACNA1C

1761

Q13936
TARPQAPATVGLAFR

ELOB

66

Q15370
FPGSQLVVTQRRFPT

DCDC2B

21

A2VCK2
TPTVFNFDIRRPSLE

FRS2

416

Q8WU20
GIARIFPSITPFVGT

DGAT2L6

126

Q6ZPD8
FPSITPFVGTLERIF

DGAT2L6

131

Q6ZPD8
SRLFVIRGQPADVFP

CRY1

71

Q16526
PRSQQPFVVTFFRAS

BMP8A

241

Q7Z5Y6
AFVRGLPTPTARFEQ

CC2D1A

626

Q6P1N0
LPTPTARFEQRTFSV

CC2D1A

631

Q6P1N0
VRGASIPFQFRPENE

CALCOCO2

116

Q13137
NFTPRVFPTALRESQ

DNAAF4

241

Q8WXU2
SPSQRLDPSRTVFVG

CPEB1

421

Q9BZB8
AFPDVSGVSRIPSRS

HEPACAM2

416

A8MVW5
TTGGAPIFDRPFTRT

DIP2A

776

Q14689
FTVPVRPFFRLGSDD

BTN2A2

476

Q8WVV5
PRSQQPFVVTFFRAS

BMP8B

241

P34820
SFTVRNVFGPIRESP

COCH

451

O43405
QRVGIFPSNYVTPRS

MAP3K9

101

P80192
GFQFTPAIRPFLQTI

LIPE

471

Q05469
VRLQFPAGATATPIT

PIDD1

341

Q9HB75
TSFVFRLPFCGPNRV

OR10G6

181

Q8NH81
QVRSERPFFSSNPEL

MEIS3P1

31

A6NDR6
RQFDRSFPTLPTLTE

RUNX3

246

Q13761
QPRRVLPSFGFTLNS

SENP2

141

Q9HC62
FTRRGAQAPPTFRAQ

SESN2

326

P58004
VFPTRTARFGSALVP

QTRT1

281

Q9BXR0
TGTRVHVFQFTRPPR

ENTPD6

111

O75354
FGAQDPVRTLPRFQT

SCRN2

336

Q96FV2
GERTFPSNPESFITR

NCOA3

256

Q9Y6Q9
AVFPPSITSRGDFLR

TANK

401

Q92844
PFRARLSGFFVAPET

PKHD1

371

P08F94
VIPRDFPFTIRVTSE

PNPT1

461

Q8TCS8
EAGPFPRARTVSVSV

NOTCH4

1836

Q99466
SIVEPGFFRTPVTNL

RDH5

201

Q92781
IQLGFVESRFFPPTR

RHPN2

176

Q8IUC4
RPTLAPVQLTNFFGT

URB1

1931

O60287
ENFPRTSEIPIFLGT

SIX6OS1

416

Q8N1H7
ELFPRRRTGFPNVTV

SPICE1

121

Q8N0Z3
RRTGFPNVTVAPDSS

SPICE1

126

Q8N0Z3
ARTRPRPVEGFEVTN

SNED1

1001

Q8TER0
RFRCPETLFQPSFIG

ACTC1

256

P68032
GRIQVPFPTQRSDSI

AMFR

496

Q9UKV5
TTFPFDPERRVRSTL

RECQL5

6

O94762
AFRPDVTSSSFQRPV

TRAF2

446

Q12933
QSDFPLGFLSRTEPR

SWI5

116

Q1ZZU3
PRSESFSISGVQPAR

TNIK

566

Q9UKE5
PSFFRTVPSDRVQLT

TAS1R3

181

Q7RTX0
RRESDPTGPQRQVFS

TTBK1

651

Q5TCY1
EPDVFAIAPFRSSRV

nan

121

Q6ZSR9
DSLDVFGQTPSPRRT

IGSF9B

1296

Q9UPX0
VGFPATPIIESRARF

SPTLC2

496

O15270
PSPAALTFRVINFSR

SGIP1

606

Q9BQI5
VGTPAARARAFFTAP

TRPM2

781

O94759
QEFFRNVCGRAPSPT

SOGA1

1291

O94964
VFPPDLVFRADQRSG

MOSPD3

36

O75425
VFSERPLRPGESLFV

NEURL1B

311

A8MQ27
GTSRPPIIVSEFRNE

SMC6

556

Q96SB8
IVFGPTLFRPEQETS

ARHGAP9

711

Q9BRR9
FTFPGRDPRATIQEQ

ROBO2

456

Q9HCK4
STRRTIEGQSPEPVF

TBC1D30

791

Q9Y2I9
AVFGTLVQPLFPESR

VWA5B2

386

Q8N398
VITRAPVLFQSPRGF

ZSCAN29

551

Q8IWY8
AVFLRGFFPAPVRSS

PIGG

21

Q5H8A4
EDVIRGANPRFTFPF

XKRX

21

Q6PP77
FDIRVPFFIRGPSVE

SULF1

336

Q8IWU6
PERVTPQSLFILFGV

PTBP1

346

P26599
PPTRIRTNKFTEGFQ

ATP6V0A2

366

Q9Y487