Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhistone H3 methyltransferase activity

SETD5 KMT2C

8.79e-0444202GO:0140938
GeneOntologyMolecularFunctionprotein-lysine N-methyltransferase activity

SETD5 KMT2C

2.09e-0368202GO:0016279
GeneOntologyMolecularFunctiontranscription coregulator activity

TRIM8 SETD5 KMT2C ZMYND8

2.10e-03562204GO:0003712
GeneOntologyMolecularFunctionlysine N-methyltransferase activity

SETD5 KMT2C

2.15e-0369202GO:0016278
GeneOntologyMolecularFunctionhistone methyltransferase activity

SETD5 KMT2C

2.27e-0371202GO:0042054
GeneOntologyMolecularFunctionmethylated histone binding

SETD5 ZMYND8

3.31e-0386202GO:0035064
GeneOntologyMolecularFunctionmethylation-dependent protein binding

SETD5 ZMYND8

3.46e-0388202GO:0140034
GeneOntologyMolecularFunctionprotein methyltransferase activity

SETD5 KMT2C

4.71e-03103202GO:0008276
GeneOntologyMolecularFunctionN-methyltransferase activity

SETD5 KMT2C

4.89e-03105202GO:0008170
HumanPhenoAbnormal morphology of bones of the upper limbs

TRIM8 LAMA5 SETD5 FBLN1 MASP1 AMMECR1

2.47e-0643676HP:0040065
HumanPhenoAbnormal upper limb bone morphology

TRIM8 LAMA5 SETD5 FBLN1 MASP1 AMMECR1

4.60e-0648476HP:0040070
HumanPhenoSynophrys

TRIM8 SETD5 MASP1 AMMECR1

6.66e-0519574HP:0000664
HumanPhenoBrachydactyly (hand)

TRIM8 LAMA5 SETD5 MASP1 AMMECR1

7.63e-0543075HP:0100667
HumanPhenoFacial hypertrichosis

TRIM8 SETD5 MASP1 AMMECR1

8.26e-0520674HP:0002219
HumanPhenoMedial flaring of the eyebrow

TRIM8 SETD5 MASP1 AMMECR1

1.23e-0422874HP:0010747
HumanPhenoAbnormal lower limb bone morphology

TRIM8 LAMA5 SETD5 FBLN1 MASP1 AMMECR1

1.42e-0486676HP:0040069
HumanPhenoShort phalanx of finger

TRIM8 LAMA5 SETD5 AMMECR1

3.87e-0430674HP:0009803
HumanPhenoAplasia/Hypoplasia of the phalanges of the hand

TRIM8 LAMA5 SETD5 AMMECR1

4.54e-0431974HP:0009767
HumanPhenoCleft palate

TRIM8 SETD5 KMT2C MASP1 AMMECR1

5.33e-0464375HP:0000175
HumanPhenoAbnormal hard palate morphology

TRIM8 SETD5 KMT2C MASP1 AMMECR1

5.49e-0464775HP:0100737
HumanPhenoBroad distal phalanx of finger

SETD5 AMMECR1

5.59e-042772HP:0009836
HumanPhenoBrachydactyly

TRIM8 LAMA5 SETD5 MASP1 AMMECR1

6.48e-0467075HP:0001156
HumanPhenoShort digit

TRIM8 LAMA5 SETD5 MASP1 AMMECR1

6.57e-0467275HP:0011927
HumanPhenoAbnormal eyebrow morphology

TRIM8 SETD5 KMT2C MASP1 AMMECR1

6.67e-0467475HP:0000534
HumanPhenoDental crowding

SETD5 MASP1 AMMECR1

7.12e-0414473HP:0000678
HumanPhenoCraniofacial cleft

TRIM8 SETD5 KMT2C MASP1 AMMECR1

7.67e-0469475HP:5201015
HumanPhenoOrofacial cleft

TRIM8 SETD5 KMT2C MASP1 AMMECR1

7.67e-0469475HP:0000202
HumanPhenoBroad phalanx

TRIM8 SETD5 AMMECR1

7.72e-0414873HP:0006009
HumanPhenoBroad phalanges of the hand

TRIM8 SETD5 AMMECR1

7.72e-0414873HP:0009768
HumanPhenoBroad finger

TRIM8 SETD5 AMMECR1

8.67e-0415473HP:0001500
HumanPhenoBroad long bones

TRIM8 SETD5 AMMECR1

9.18e-0415773HP:0005622
HumanPhenoBifid uvula

SETD5 KMT2C AMMECR1

1.10e-0316773HP:0000193
HumanPhenoGlomerulopathy

TRIM8 LAMA5 AMMECR1

1.20e-0317273HP:0100820
HumanPhenoHypertrichosis

TRIM8 SETD5 MASP1 AMMECR1

1.36e-0342574HP:0000998
HumanPhenoAbnormal cardiac septum morphology

TRIM8 LAMA5 SETD5 MASP1 AMMECR1

1.39e-0378775HP:0001671
HumanPhenoFlared metaphysis

TRIM8 SETD5 AMMECR1

1.62e-0319173HP:0003015
HumanPhenoAbnormal long bone morphology

TRIM8 LAMA5 SETD5 MASP1 AMMECR1

1.70e-0382175HP:0011314
HumanPhenoAbnormal male external genitalia morphology

TRIM8 LAMA5 SETD5 KMT2C FBLN1 MASP1

1.70e-03132976HP:0000032
HumanPhenoAbnormal uvula morphology

SETD5 KMT2C AMMECR1

1.78e-0319773HP:0000172
HumanPhenoAbnormal external genitalia

TRIM8 LAMA5 SETD5 KMT2C FBLN1 MASP1

2.04e-03137276HP:0000811
MousePhenoabnormal truncus arteriosus septation

LAMA5 SETD5 FBLN1

9.04e-0584153MP:0010454
MousePhenoabnormal glomerular capillary endothelium morphology

LAMA5 FBLN1

2.23e-0421152MP:0011453
MousePhenoabnormal thymus size

LAMA5 SETD5 FBLN1 GPRC6A RNF208

2.25e-04564155MP:0002364
MousePhenosmall thyroid gland

SETD5 FBLN1

2.45e-0422152MP:0002951
MousePhenoabnormal aortic arch morphology

LAMA5 SETD5 FBLN1

2.54e-04119153MP:0004113
MousePhenoabnormal cardiac outflow tract development

LAMA5 SETD5 FBLN1

3.60e-04134153MP:0006126
MousePhenoabnormal thoracic aorta morphology

LAMA5 SETD5 FBLN1

3.60e-04134153MP:0010468
MousePhenodouble outlet right ventricle

LAMA5 SETD5 FBLN1

5.01e-04150153MP:0000284
MousePhenoabnormal thymus morphology

LAMA5 SETD5 FBLN1 GPRC6A RNF208

6.83e-04717155MP:0000703
MousePhenoabnormal right subclavian artery morphology

LAMA5 FBLN1

8.19e-0440152MP:0010487
MousePhenoabnormal carotid artery morphology

SETD5 FBLN1

9.91e-0444152MP:0004181
MousePhenoabnormal glomerular capillary morphology

LAMA5 FBLN1

1.13e-0347152MP:0011320
MousePhenoabnormal kidney capillary morphology

LAMA5 FBLN1

1.18e-0348152MP:0011310
MousePhenoabnormal heart and great artery attachment

LAMA5 SETD5 FBLN1

1.24e-03205153MP:0010426
MousePhenoabnormal heart and great vessel attachment

LAMA5 SETD5 FBLN1

1.29e-03208153MP:0010425
MousePhenoabnormal trophoblast layer morphology

LAMA5 SETD5 FBXO5

1.35e-03211153MP:0005031
DomainWBP1-like

WBP1 WBP1L

6.53e-064202IPR021684
DomainWBP-1

WBP1 WBP1L

6.53e-064202PF11669
DomainZf-RING_9

DEF8 RUBCNL

1.09e-055202IPR025258
Domainzf-RING_9

DEF8 RUBCNL

1.09e-055202PF13901
DomainDUF4206

DEF8 RUBCNL

1.09e-055202SM01175
DomainRING

DEF8 TRIM8 KMT2C RNF208

2.75e-04305204SM00184
DomainZnf_RING

DEF8 TRIM8 KMT2C RNF208

3.54e-04326204IPR001841
DomainSET

SETD5 KMT2C

8.71e-0441202PF00856
DomainSET

SETD5 KMT2C

1.10e-0346202SM00317
Domain-

TRIM8 KMT2C RNF208 ZMYND8

1.18e-034492043.30.40.10
DomainZnf_RING/FYVE/PHD

TRIM8 KMT2C RNF208 ZMYND8

1.28e-03459204IPR013083
DomainSET_dom

SETD5 KMT2C

1.29e-0350202IPR001214
DomainSET

SETD5 KMT2C

1.29e-0350202PS50280
DomainC1

DEF8 KMT2C

2.18e-0365202SM00109
DomainPE/DAG-bd

DEF8 KMT2C

2.24e-0366202IPR002219
DomainEGF-like_dom

LAMA5 FBLN1 MASP1

2.26e-03249203IPR000742
DomainEGF_1

LAMA5 FBLN1 MASP1

2.41e-03255203PS00022
DomainEGF-like_CS

LAMA5 FBLN1 MASP1

2.58e-03261203IPR013032
DomainEGF_2

LAMA5 FBLN1 MASP1

2.69e-03265203PS01186
DomainPHD

KMT2C ZMYND8

2.88e-0375202PF00628
DomainZnf_PHD-finger

KMT2C ZMYND8

3.19e-0379202IPR019787
DomainZF_RING_2

TRIM8 KMT2C RNF208

3.75e-03298203PS50089
DomainEGF_CA

FBLN1 MASP1

3.77e-0386202PF07645
DomainPHD

KMT2C ZMYND8

4.03e-0389202SM00249
DomainZnf_PHD

KMT2C ZMYND8

4.21e-0391202IPR001965
DomainZF_PHD_2

KMT2C ZMYND8

4.58e-0395202PS50016
DomainZF_PHD_1

KMT2C ZMYND8

4.68e-0396202PS01359
DomainEGF_Ca-bd_CS

FBLN1 MASP1

4.77e-0397202IPR018097
DomainEGF_CA

FBLN1 MASP1

4.97e-0399202PS01187
DomainASX_HYDROXYL

FBLN1 MASP1

5.06e-03100202PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBLN1 MASP1

5.67e-03106202IPR000152
DomainEGF_CA

FBLN1 MASP1

7.45e-03122202SM00179
DomainEGF-like_Ca-bd_dom

FBLN1 MASP1

7.68e-03124202IPR001881
DomainZnf_FYVE_PHD

KMT2C ZMYND8

1.07e-02147202IPR011011
DomainGrowth_fac_rcpt_

LAMA5 FBLN1

1.19e-02156202IPR009030
DomainZnf_RING_CS

TRIM8 RNF208

1.30e-02163202IPR017907
Pubmed

Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array.

TRIM8 LAMA5 WBP1L FBXO5

4.88e-0620120423535732
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

LAMA5 FBLN1

2.44e-051320212682087
InteractionHOXA1 interactions

TRIM8 LAMA5 FBLN1 RNF208 AMMECR1

1.19e-05356185int:HOXA1
CytobandEnsembl 112 genes in cytogenetic band chr10q24

TRIM8 WBP1L

3.36e-03189212chr10q24
CytobandEnsembl 112 genes in cytogenetic band chr21q22

KRTAP21-3 KRTAP21-2

1.27e-02377212chr21q22
CytobandEnsembl 112 genes in cytogenetic band chr20q13

LAMA5 ZMYND8

1.58e-02422212chr20q13
GeneFamilyPHD finger proteins

KMT2C ZMYND8

2.14e-039014288
GeneFamilyKeratin associated proteins

KRTAP21-3 KRTAP21-2

3.13e-03109142619
GeneFamilyRing finger proteins

TRIM8 RNF208

1.86e-0227514258
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-liver_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

MASP1 RUBCNL CYYR1

5.19e-05156213411c170a7dd65269ae442b8069caf5231bddb116
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA5 MASP1 RUBCNL

5.39e-05158213e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA5 MASP1 RUBCNL

5.39e-05158213d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCellPBMC-Mild-cDC_11|Mild / Compartment, Disease Groups and Clusters

LAMA5 RUBCNL CYYR1

7.56e-05177213974305e4c0eff90134c4e58cf11b955d1eee0501
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

PRICKLE2 LAMA5 ZMYND8

8.89e-051872137e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_Aerocyte_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 MASP1 CYYR1

9.18e-0518921309dd2b3d89416192e84abe302a6237b8f3fdcb6e
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 LAMA5 CYYR1

9.91e-0519421368004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PRICKLE2 FBLN1 SHISA6

1.07e-0419921395d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_ventral_progenitors|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

FBLN1 AMMECR1 FBXO5

1.07e-04199213446cd7d960812519fe2b8e434578ef0b668c75ce
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Macroglial-Astrocyte|5w / Sample Type, Dataset, Time_group, and Cell type.

FBLN1 MASP1 AMMECR1

1.08e-04200213b64f3f1484de49777efb9b998577ff6bbb6e6861
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PRICKLE2 FBLN1 MASP1

1.08e-042002138ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPRC6A SHISA6

9.79e-0499212c8fcfc92bcb0c19dc4aaf4e67d263b936d41d589
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_2|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPRC6A SHISA6

9.99e-0410021232219094edb6e3c81222d5fcfbf222b7fdc58fa3
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

MASP1 SHISA6

1.02e-03101212cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCellTCGA-Ovary-Primary_Tumor|TCGA-Ovary / Sample_Type by Project: Shred V9

TRIM8 FBLN1

1.12e-0310621214f548be39cec604fbdae0382cbf434fa4049840
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

TRIM8 FBLN1

1.12e-03106212939b80950d39cdc7149a05fdfb64c8810064cdb1
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma|TCGA-Ovary / Sample_Type by Project: Shred V9

TRIM8 FBLN1

1.12e-03106212e9e1b55f32b3d5b9eeec94a997912e5c21c1fb48
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.14e-03107212fc07dd90f280191bd643398eac5c8273651d0925
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.32e-03115212ac73aa06e617ed791c6ae9e38189bac74188c27b
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.41e-03119212e868453c02dcf0e07821886b81ca739887d43c67
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Esm1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.46e-03121212056d0f0f7a4d1b2d38b83647bbe4468b7c959ce6
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Sema3c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.48e-03122212eae9d94f8510ac0f434942451d55c7260977b178
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.55e-03125212d05556ea185c15815a4f8643f1c01185badbeece
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Hpse_Cbln4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.58e-0312621294bd9cfe982b41a3114885173eab55feb0fbbbae
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Myh4|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.65e-03129212f83187c0bb06528127b8d2d56674ab1946846951
ToppCellcontrol-Plasmablast|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LAMA5 RUBCNL

1.68e-031302129fe3c5be8488d341cff38757daf7856c112410d0
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMMECR1 CYYR1

1.73e-0313221246c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCellLPS-IL1RA+antiTNF-Unknown|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AMMECR1 CYYR1

1.73e-03132212a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

1.83e-03136212e3a2425ba5ef538dbacab1479e682837ae42a888
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

MASP1 RNF208

2.00e-03142212199a0a1024b6cc446f5ca1f277846a2bdb227a9f
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Ptgdr|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

2.05e-0314421271107275767a0728541a3695715c44874b3e5efc
ToppCellCOVID-19-Mast_cells-Transitioning_MDM|COVID-19 / group, cell type (main and fine annotations)

WBP1 CYYR1

2.08e-031452125c5fed4620c4c312d1052b8acad910453f7e8fcc
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA5 SHISA6

2.11e-0314621247368f981180ca6a8c81a50f7f9430f12456f609
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

2.14e-0314721250e86860a94be103092c40e39a172eac92372f0d
ToppCellTCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-4|TCGA-Bladder / Sample_Type by Project: Shred V9

SHISA6 TAAR6

2.22e-03150212bcb99c6fa81052556ab30f9db5875fccf1ae724b
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MASP1 RUBCNL

2.28e-031522120652ee3443e6fbb679d2c4f326239ae7c803f924
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMA5 FBLN1

2.31e-031532128bc09b8b1a32a8d7ac8201c626d2b306e7cc2972
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBLN1 SHISA6

2.34e-0315421244d4d99b08216c0901e3bc32743fa0a8b85b5149
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RUBCNL CYYR1

2.34e-031542125967a0a33456d5930fc492a700ebb015ac050abb
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

PRICKLE2 CYYR1

2.34e-03154212212c340a096a3a9669d1aebd61c045cf1402a868
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RUBCNL CYYR1

2.37e-03155212fab281db4c275d51240b122be78713c839ba5a95
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHISA6 AMMECR1

2.43e-03157212370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

PRICKLE2 RUBCNL

2.43e-031572122c1219ee19a6246a3b9f5c2c1a37f26ea934a822
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GPRC6A CYYR1

2.43e-03157212275a4c6fef1fff8da2bdc48e3924ad05c5e5cfc8
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 LAMA5

2.43e-031572126ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMA5 SHISA6

2.49e-031592128680b054622f573a82b1625fb93c2d5db81d1034
ToppCellControl-Endothelial_cells-Inflamed_endothelial_cells|Control / group, cell type (main and fine annotations)

PRICKLE2 CYYR1

2.52e-03160212958256e3d3836160763b82bb48f794087918d935
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FBLN1 RUBCNL

2.52e-0316021261f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

2.52e-03160212dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

FBLN1 RUBCNL

2.52e-0316021234b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellCOVID-19-kidney-Epithelial_(EC)|kidney / Disease (COVID-19 only), tissue and cell type

CYYR1 KRTAP21-2

2.52e-031602120d4880f85565d8c540c94a8f8109147b3029279a
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chrna2_Glra3|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

2.52e-031602120bfdaf979e6f128cba2928ce16bca4d3deff8ac9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

2.56e-03161212bf70be1de418615b5442ec684552551edaf1f072
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

MASP1 SHISA6

2.56e-03161212dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCellChildren_(3_yrs)-Immune-dendritic_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RUBCNL CYYR1

2.59e-0316221286a0b9dabd150dc993bfc0f3344804de7f8e4042
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WBP1 CYYR1

2.62e-0316321273c03e29a6d7a6863c5e9aa5e8b963ef691f1ddb
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MASP1 SHISA6

2.65e-03164212dd29decc6c41a580cfdf03962827ec18d432935f
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

MASP1 SHISA6

2.65e-03164212dcd3c3ee73900180451fad9b4de0efedbd375e1c
ToppCellfacs-Heart-LA-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRC6A SHISA6

2.68e-0316521295866f7cc6eb1bb51a034a104a0eb2a53b0256f2
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LAMA5 SHISA6

2.68e-03165212c6b23013d77fa9aa967b76e451c8e42b0a657c30
ToppCellfacs-Heart-LA-18m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPRC6A SHISA6

2.68e-03165212f8bfe336b9a4460b9349c01acd0bd3167812662f
ToppCelllymphoid-B_cell-pro-B|lymphoid / Lineage, cell class and subclass

FBLN1 CYYR1

2.68e-031652128126c2f7810fc6e09b18783aadf6434ae12b0514
ToppCell10x5'-Liver-Myeloid_Dendritic-pDC|Liver / Manually curated celltypes from each tissue

RUBCNL CYYR1

2.71e-0316621224dfa9f3e0842f9ab8350bf6a52ae0d10f2a0c44
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|metastatic_Lymph_Node / Location, Cell class and cell subclass

RUBCNL CYYR1

2.71e-031662129f14e3ef19d5903278c040be1c477501237173fa
ToppCell356C-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL CYYR1

2.71e-03166212971ee6602a1e751f453f9d823295e63dadce62bf
ToppCell356C-Myeloid-Dendritic-cDC1|356C / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL CYYR1

2.71e-031662120590e404f45afce90e20f93f90a3def83949c66b
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

WBP1 CYYR1

2.75e-031672126c2dade24a88af04b2c90a7e4f8dd7ccea9e94d1
ToppCelldroplet-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea-|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AMMECR1 CYYR1

2.75e-03167212774f3264318b002d0df5d06d41d645366038d0bf
ToppCellfacs-Aorta-Heart-24m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MASP1 WBP1L

2.78e-03168212edbab94f14e16a1a76546a18fe777a183080d1de
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

DEF8 SHISA6

2.78e-0316821200646601548b0fee42ae16bfa5e93603bc7c5129
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

RUBCNL CYYR1

2.78e-0316821290f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellB_cells-pDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

RUBCNL CYYR1

2.78e-03168212dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCellNS-moderate-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

RUBCNL CYYR1

2.78e-03168212d03e91f0e0518b33555c0ec98124fc5ed0f11be5
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHISA6 RUBCNL

2.78e-03168212e8878ec68b21c8d5694d7209b816d2f869673164
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DEF8 AMMECR1

2.78e-03168212a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCelldroplet-Liver-LIVER-NPC-1m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHISA6 RUBCNL

2.78e-03168212a007758c219d3d5db2b5529f29af63be0d408304
ToppCell367C-Fibroblasts-Fibroblast-G-|367C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE2 FBLN1

2.78e-03168212b8c65542a0701ae31f49d332d87a64578e24b4e3
ToppCell390C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

WBP1 CYYR1

2.78e-03168212d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell367C-Fibroblasts-Fibroblast-G|367C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE2 FBLN1

2.78e-031682128c95093b1ea45826f62893edd3c410fe53b563a4
ToppCelldroplet-Heart-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN1 WBP1L

2.81e-031692122e5bb6437bc9c614e337c5ffb6f6457cd9fc7f4c
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

MASP1 SHISA6

2.81e-0316921258098f8801ca941aeddafb47e88ab0df8b9edb57
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RUBCNL CYYR1

2.81e-03169212a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCell368C-Fibroblasts-Fibroblast-B_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

MASP1 SHISA6

2.81e-031692121d5ce2c97f7ef7bdc9f861938077a9aa31d84db6
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRICKLE2 CYYR1

2.81e-0316921287116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 LAMA5

2.84e-03170212a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCellPND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FBLN1 SHISA6

2.84e-03170212e20568c8f3f17d94de78229617eb2f7e4c5af2bc
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Proliferating-cycling_ventral_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FBLN1 FBXO5

2.84e-0317021273601c873b177d5d134618d8e228c51381119f7d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CYYR1 FBXO5

2.88e-03171212c2dbc439af28d4fabb24d57685b75b2e588819b0
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

RUBCNL CYYR1

2.88e-031712126a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCell356C-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

RUBCNL CYYR1

2.88e-031712123d60e7ecf25e4b781ba2387671b2aad247fb75ff
ToppCellChildren_(3_yrs)-Immune-dendritic_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

RUBCNL CYYR1

2.88e-031712126a5ac0f56bd7b4543be103100fb735ca6bc5b8bf
ToppCellCOVID-pDC|COVID / Condition, Cell_class and T cell subcluster

RUBCNL CYYR1

2.91e-031722123ecbb000495dde32f6153ef6bdea9c8802ff3985
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MASP1 CYYR1

2.91e-03172212e359c59631f6a262429b6896a409f2ffbd4f6a76
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBLN1 FBXO5

2.91e-0317221235c20de4db47dbf31c857d23c7a25cd7f95c085c
ToppCell10x5'-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

RUBCNL CYYR1

2.91e-03172212243b8bb01cbec5c1bf8802cbf8a6153356b4c384
ToppCellEndothelial-A-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MASP1 CYYR1

2.91e-03172212a3201773a25832e92dd113fad165f1ecd37f5e91
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

RUBCNL CYYR1

2.91e-031722121215f61f115b042f84721b64c2ed1f48081535f1
ToppCellCOVID-pDC-|COVID / Condition, Cell_class and T cell subcluster

RUBCNL CYYR1

2.91e-03172212a7827faa1afab51fdaf0cb1a2babcd2e00d411e5
DiseaseNeurodevelopmental Disorders

SETD5 KMT2C

1.45e-0393182C1535926
DiseaseHypermetropia

PRICKLE2 SHISA6

1.78e-03103182HP_0000540
Diseaseage at onset, Myopia

DEF8 SHISA6

3.72e-03150182EFO_0004847, HP_0000545
Diseaseprostate cancer (is_marker_for)

SETD5 KMT2C

4.02e-03156182DOID:10283 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
YCEYLGKYFCDCCHS

RUBCNL

451

Q9H714
GKYFCDCCHSYAESC

RUBCNL

456

Q9H714
ACSQCGQCYHPYCVS

KMT2C

976

Q8NEZ4
KSYCCDGTTPYCCSY

CYYR1

36

Q96J86
CQSCNCYGHATDCYY

LAMA5

356

O15230
CCYECQNCPENHYTN

GPRC6A

541

Q5T6X5
PYCCHCFESLYAEYC

PRICKLE2

241

Q7Z3G6
SQECANVYGSYQCYC

FBLN1

451

P23142
CGFDYCTKCLCNYHT

FBXO5

401

Q9UKT4
YCHNYIGGYYCSCRF

MASP1

156

P48740
QCDYTGQYYCSHCHW

DEF8

296

Q6ZN54
MCCNYYRNCCGGCGY

KRTAP21-2

1

Q3LI59
HSTHCGCNGYYGCYE

KRTAP21-3

26

Q3LHN1
IFYCCWNTSYCDYPC

ZMYND8

1036

Q9ULU4
CIYEICCWCAYYNSA

TAAR6

291

Q96RI8
YEYSNCNYKVDCACH

SETD5

391

Q9C0A6
NNSESGYLYCCGTCY

SHISA6

111

Q6ZSJ9
GYLYCCGTCYYRFCC

SHISA6

116

Q6ZSJ9
CCFCFDVLYCHLYGY

AMMECR1

131

Q9Y4X0
YQTFRQYCGAACTCH

RNF208

236

Q9H0X6
VAVCQYCCYYSGAHQ

TRIM8

161

Q9BZR9
YCCYYSGAHQGHSVC

TRIM8

166

Q9BZR9
TGHCCGQSQCCNYYY

WBP1L

26

Q9NX94
GHCCGETGCCTYYYE

WBP1

41

Q96G27