Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7

3.03e-0737314GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7

3.38e-0738314GO:0070001
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-8 ERVK-6 ERVK-7

5.54e-0711313GO:0004523
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-8 ERVK-6 ERVK-7

1.22e-0614313GO:0003964
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-8 ERVK-6 ERVK-7

4.42e-0621313GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-8 ERVK-6 ERVK-7

2.54e-0537313GO:0016891
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-8 ERVK-6 ERVK-7

2.75e-0538313GO:0034061
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-8 ERVK-6 ERVK-7

4.92e-0546313GO:0016893
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-8 ERVK-6 ERVK-7

2.47e-0479313GO:0004521
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-8 ERVK-6 ERVK-7

1.21e-03136313GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-8 ERVK-6 ERVK-7

1.21e-03136313GO:0004519
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-8 ERVK-6 ERVK-7

1.66e-03152313GO:0016779
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-8 SPTBN4 ERVK-6 ERVK-19 EIF3A ERVK-7

2.19e-03891316GO:0005198
GeneOntologyMolecularFunctionzinc ion binding

ERVK-8 PRICKLE2 ERVK-6 KDM2B ERVK-19 ERVK-7

2.19e-03891316GO:0008270
GeneOntologyMolecularFunctionpeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7 USP42

3.11e-03654315GO:0008233
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-8 ERVK-6 ERVK-19 ERVK-7

4.21e-03430314GO:0004175
GeneOntologyBiologicalProcessDNA integration

ERVK-8 ERVK-6 ERVK-7

8.70e-0713313GO:0015074
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-8 ERVK-6 ERVK-7

5.08e-0548313GO:0000731
GeneOntologyBiologicalProcessviral process

ERVK-8 ERVK-6 ERVK-19 EIF3A ERVK-7 CD80

5.73e-05464316GO:0016032
GeneOntologyBiologicalProcessregulation of stem cell population maintenance

KDM2B ING2 ZC3H13

2.17e-0478313GO:2000036
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-8 ERVK-6 ERVK-7

2.60e-0483313GO:0006278
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-8 ERVK-6 ERVK-19

2.79e-0485313GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-8 ERVK-6 ERVK-19

2.79e-0485313GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-8 ERVK-6 ERVK-19

3.20e-0489313GO:0006949
GeneOntologyBiologicalProcessregulation of leukocyte differentiation

TJP2 KLF10 RIPK1 ZNF608 CD80

4.14e-04429315GO:1902105
GeneOntologyBiologicalProcessstem cell population maintenance

KDM2B KLF10 ING2 ZC3H13

4.19e-04237314GO:0019827
GeneOntologyBiologicalProcessmaintenance of cell number

KDM2B KLF10 ING2 ZC3H13

4.53e-04242314GO:0098727
DomainDVL-1

DVL1P1 DVL1

2.49e-062302IPR008340
DomainDishevelled

DVL1P1 DVL1

1.49e-054302PF02377
DomainDishevelled_protein_dom

DVL1P1 DVL1

1.49e-054302IPR003351
DomainDishevelled_fam

DVL1P1 DVL1

1.49e-054302IPR008339
DomainDIX

DVL1P1 DVL1

5.21e-057302IPR001158
DomainDIX

DVL1P1 DVL1

5.21e-057302PS50841
DomainDAX

DVL1P1 DVL1

5.21e-057302SM00021
DomainDIX

DVL1P1 DVL1

5.21e-057302PF00778
DomainDEP

DVL1P1 DVL1

5.65e-0422302PF00610
DomainDEP

DVL1P1 DVL1

5.65e-0422302SM00049
DomainDEP

DVL1P1 DVL1

5.65e-0422302PS50186
DomainDEP_dom

DVL1P1 DVL1

6.18e-0423302IPR000591
DomainPDZ

TJP2 DVL1P1 DVL1

1.47e-03141303PF00595
DomainPDZ

TJP2 DVL1P1 DVL1

1.69e-03148303SM00228
DomainPDZ

TJP2 DVL1P1 DVL1

1.79e-03151303PS50106
DomainPDZ

TJP2 DVL1P1 DVL1

1.83e-03152303IPR001478
DomainF-box

KDM2B FBXL22

5.17e-0367302PF00646
DomainFBOX

KDM2B FBXL22

5.95e-0372302PS50181
DomainF-box_dom

KDM2B FBXL22

6.44e-0375302IPR001810
DomainWHTH_DNA-bd_dom

EIF3A DVL1P1 DVL1

6.74e-03242303IPR011991
DomainZnf_PHD-finger

KDM2B ING2

7.12e-0379302IPR019787
DomainPHD

KDM2B ING2

8.96e-0389302SM00249
DomainZnf_PHD

KDM2B ING2

9.35e-0391302IPR001965
DomainZF_PHD_2

KDM2B ING2

1.02e-0295302PS50016
DomainZF_PHD_1

KDM2B ING2

1.04e-0296302PS01359
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7

8.52e-09534312629516
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-8 ERVK-6 ERVK-19

1.87e-071234314557543
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

9.28e-0723429060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

9.28e-0723429460924
Pubmed

Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.

DVL1P1 DVL1

9.28e-0723428644734
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-8 ERVK-6 ERVK-19 ERVK-7

2.18e-069434421542922
Pubmed

Prickle promotes neurite outgrowth via the Dishevelled dependent pathway in C1300 cells.

PRICKLE2 DVL1

2.78e-06334219788910
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

2.78e-06334210516026
Pubmed

cDNA characterization and chromosomal mapping of two human homologues of the Drosophila dishevelled polarity gene.

DVL1P1 DVL1

5.56e-0643428817329
Pubmed

Human dishevelled genes constitute a DHR-containing multigene family.

DVL1P1 DVL1

5.56e-0643429192851
Pubmed

Distortion product otoacoustic emissions in hearing-impaired mutant mice.

SPTBN4 SRRM4

5.56e-0643424067076
Pubmed

Non-canonical Wnt signaling induces ubiquitination and degradation of Syndecan4.

DVL1P1 DVL1

5.56e-06434220639201
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19

5.56e-0643427983737
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7

5.56e-06434210469592
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

9.26e-06534211401426
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19

1.39e-05634215063128
Pubmed

USP42 protects ZNRF3/RNF43 from R-spondin-dependent clearance and inhibits Wnt signalling.

USP42 DVL1

1.94e-05734233786993
Pubmed

SR protein kinases promote splicing of nonconsensus introns.

SPTBN4 TJP2 SNIP1 EIF3A ZC3H13

2.55e-0536134526167880
Pubmed

A coated vesicle-associated kinase of 104 kDa (CVAK104) induces lysosomal degradation of frizzled 5 (Fzd5).

DVL1P1 DVL1

2.59e-05834219643732
Pubmed

Expression of planar cell polarity genes during development of the mouse CNS.

PRICKLE2 DVL1

3.33e-05934216487141
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

KDM2B USP42 ING2 CBX8 LRRC41

3.96e-0539634526687479
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19

4.15e-051034212970426
Pubmed

The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins.

TJP2 SNIP1 ZC3H13 DVL1

4.56e-0520334435012549
Pubmed

A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.

TJP2 SNIP1 KLF10

5.07e-057334322094256
Pubmed

USP7 is a novel Deubiquitinase sustaining PLK1 protein stability and regulating chromosome alignment in mitosis.

KDM2B DYNC2I1

5.07e-051134231730000
Pubmed

Human transcription factor protein interaction networks.

KDM2B EIF3A KLF10 ZNF608 ING2 SCAF4 ZNF516 RLIM

5.56e-05142934835140242
Pubmed

Microtubules enable the planar cell polarity of airway cilia.

PRICKLE2 DVL1

6.08e-051234223122850
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TJP2 KDM2B USP42 ZC3H13 SCAF4 ZNF516

9.41e-0577434615302935
Pubmed

MIND bomb 2 prevents RIPK1 kinase activity-dependent and -independent apoptosis through ubiquitylation of cFLIPL.

RIPK1 RLIM

1.25e-041734233469115
Pubmed

Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance.

PRICKLE2 DVL1

1.25e-041734221316586
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

KDM2B TNRC18 ZNF608 ING2

1.33e-0426834433640491
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

TNRC18 ING2 XPO5

1.72e-0411034326841866
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

KDM2B SNIP1 USP42 ING2 ZC3H13 CBX8 SCAF4

2.16e-04129434730804502
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

TJP2 SNIP1 EIF3A USP42 ING2 XPO5 ZC3H13

2.42e-04131834730463901
Pubmed

BCOR modulates transcriptional activity of a subset of glucocorticoid receptor target genes involved in cell growth and mobility.

KDM2B ZNF608

2.53e-042434233722704
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

TJP2 RIPK1 ZC3H13

3.00e-0413334315144186
Pubmed

Interaction network of human early embryonic transcription factors.

KDM2B TNRC18 ZNF608 ZNF516

3.72e-0435134438297188
Pubmed

Planar cell polarity controls pancreatic beta cell differentiation and glucose homeostasis.

PRICKLE2 DVL1

4.52e-043234223177622
Pubmed

Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.

EIF3A RIPK1

4.52e-043234220056645
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

TNRC18 USP42 ZNF516 RLIM DNAH11

5.20e-0468934536543142
Pubmed

Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.

SNIP1 DVL1P1 DVL1

5.24e-0416134336398662
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

KDM2B TNRC18 ZNF608 ZNF516

5.97e-0439834435016035
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

TJP2 EIF3A XPO5

6.04e-0416934331462741
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

KDM2B ZNF608 ZNF516 DVL1

7.17e-0441834434709266
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

KDM2B CBX8

7.43e-044134222325352
Pubmed

Genetic loci associated with circulating levels of very long-chain saturated fatty acids.

ZNF608 ZNF516

7.79e-044234225378659
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

SNIP1 EIF3A RIPK1 CBX8 LRRC41

7.81e-0475434533060197
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

KDM2B CBX8

8.55e-044434227505670
Pubmed

ANKRD13a controls early cell-death checkpoint by interacting with RIP1 independent of NF-κB.

RIPK1 SCAF4

8.55e-044434234839354
Pubmed

The CRL4DCAF6 E3 ligase ubiquitinates CtBP1/2 to induce apoptotic signalling and promote intervertebral disc degeneration.

KDM2B KLF10 DVL1

9.69e-0419934336688959
Pubmed

Proteomics analysis of the centromere complex from HeLa interphase cells: UV-damaged DNA binding protein 1 (DDB-1) is a component of the CEN-complex, while BMI-1 is transiently co-localized with the centromeric region in interphase.

ZC3H13 CBX8

9.75e-044734215009096
Pubmed

Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.

PRICKLE2 DVL1

9.75e-044734233141892
InteractionGAGE5 interactions

TJP2 SNIP1 ZC3H13 SCAF4

1.18e-0652314int:GAGE5
InteractionPSENEN interactions

TJP2 SNIP1 ZC3H13 SCAF4

7.02e-0681314int:PSENEN
InteractionGSC interactions

KDM2B TNRC18 ZNF608 ZNF516

9.33e-0687314int:GSC
InteractionLINC02910 interactions

TJP2 SNIP1 DYNC2I1 ZC3H13

1.32e-0595314int:LINC02910
InteractionSNRNP40 interactions

SNIP1 ZNF608 USP42 ZC3H13 CBX8 SCAF4 DVL1

4.14e-05637317int:SNRNP40
InteractionUQCR11 interactions

TJP2 SNIP1 ZC3H13

7.33e-0553313int:UQCR11
InteractionIFI6 interactions

TJP2 SNIP1 ZC3H13

7.75e-0554313int:IFI6
InteractionIFI27L1 interactions

TJP2 SNIP1 ZC3H13

1.35e-0465313int:IFI27L1
InteractionVSX1 interactions

KDM2B ZNF608 ZNF516

1.41e-0466313int:VSX1
Cytoband7p22.1

ERVK-6 TNRC18 USP42

5.37e-06473337p22.1
CytobandEnsembl 112 genes in cytogenetic band chr7p22

TNRC18 USP42

4.21e-03134332chr7p22
GeneFamilyF-box and leucine rich repeat proteins

KDM2B FBXL22

3.49e-0421242558
GeneFamilyPHD finger proteins

KDM2B ING2

6.30e-039024288
GeneFamilyPDZ domain containing

TJP2 DVL1

1.72e-021522421220
ToppCell368C-Fibroblasts-Fibroblast-H|368C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE2 NHS LRRC41

1.44e-041523039f3682da00fd627e80aa820ecc6f5fed23b9738a
ToppCell368C-Fibroblasts-Fibroblast-H-|368C / Donor, Lineage, Cell class and subclass (all cells)

PRICKLE2 NHS LRRC41

1.44e-04152303dbfb4d4de36ef9f5c7da1950baa915b12788685e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS SRRM4

1.67e-041603032d391ba6f7adb55dfa89feecc10cc9ce97e5fe74
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS SRRM4

1.67e-041603038bcdbcfdf1e0ace6053e8de82762f6e2f86bba7a
ToppCell343B-Myeloid-Dendritic-cDC_activated|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KDM2B CD80 DNAH11

1.80e-04164303eae6d440877b292ad18dc4bd02802dda5b2f9c60
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP42 ING2 LRRC41

1.83e-041653030edd56e8d14eaeced9882dd9206ea93e8f402e8d
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP42 ING2 LRRC41

1.83e-04165303fa3aadfff6fb1e7f142db333c60c2cba02b17e6c
ToppCell5'-Adult-LymphNode-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDM2B CD80 DNAH11

1.86e-04166303da10d0be6b616199d49dd922591c2901f9681583
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KDM2B CD80 DNAH11

1.89e-041673038b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2I1 AHI1-DT DNAH11

1.96e-04169303fba841664939c771881ba97f14ef1df6635c04ff
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM2B USP42 DVL1

2.14e-04174303ff13a5c55d18b951315908f33cb47c7f9cb901bf
ToppCellmetastatic_Brain-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

TJP2 KDM2B DNAH11

2.21e-041763039c1f255de3082b3da4bef2a9bdff710cfd48261f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS AHI1-DT

2.40e-0418130322363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 SPTBN4 NHS

2.52e-04184303e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

PRICKLE2 KDM2B TNRC18

2.60e-04186303de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

PRICKLE2 KDM2B TNRC18

2.60e-041863030b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NHS AHI1-DT DNAH11

2.60e-04186303f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS AHI1-DT

2.72e-04189303aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS AHI1-DT

2.72e-041893038977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS ZNF608

2.77e-04190303989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS ZNF608

2.81e-041913031cb02007adb344f17ef73d58890f91298c7cf5a1
ToppCell(3)_MNP-(3)_DC_activated|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

KDM2B CD80 DNAH11

2.81e-041913030353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCellChildren_(3_yrs)-Epithelial-club_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRICKLE2 NHS ZNF608

2.81e-0419130323776c7302cead3881b39127398f3b3e0d27885e
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DYNC2I1 ZNF608 DNAH11

2.90e-04193303ea345d34440b25f65358a53dc72831998d1c3620
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

KDM2B ZNF608 CD80

2.90e-04193303a2194012dfa0174c6160900625c44e0fd04c50e7
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DYNC2I1 AHI1-DT DNAH11

2.90e-04193303ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_10|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

KDM2B ZNF608 CD80

2.90e-041933037426a30ed01e5c8376b3e0ebe0f1057cfee88340
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS AHI1-DT

2.99e-04195303938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PRICKLE2 NHS AHI1-DT

2.99e-04195303d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellIPF-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

PRICKLE2 AHI1-DT DNAH11

2.99e-0419530321dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCellCOPD-Multiplet-Multiplet|COPD / Disease state, Lineage and Cell class

PRICKLE2 AHI1-DT DNAH11

3.03e-04196303af4cdc61830685a888a1209826c23bcf54a43084
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

PRICKLE2 AHI1-DT DNAH11

3.03e-0419630387d9881cfec461a5d89b688a83749b618c519485
ToppCellCOPD-Multiplet|COPD / Disease state, Lineage and Cell class

PRICKLE2 AHI1-DT DNAH11

3.03e-041963036d02d494196e3f857d53eea46d9419690d43beca
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

DYNC2I1 EIF3A ZC3H13

3.08e-041973030fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellCOVID-19-Myeloid-Migratory_DC|COVID-19 / Condition, Lineage and Cell class

KDM2B ZNF608 CD80

3.08e-04197303b6d6cdae33753c1e38394f1f879e00b87f9c0496
ToppCellfacs-Diaphragm-Limb_Muscle-3m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF3A RIPK1 RLIM

3.08e-04197303b0e2ea81308bce289cb7cbea0e27de1d01afeed2
ToppCellCOVID-19-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

KDM2B ZNF608 CD80

3.12e-0419830390f3b227cbc61c268d6d94bc9945a08d83d2d3d5
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

DYNC2I1 ZC3H13 RLIM

3.17e-0419930361b1ed2db71b96157b92b7535d1955a4033098da
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

DYNC2I1 ZC3H13 RLIM

3.17e-04199303fc680f85ebd3bab4c72876a19a461b0afb5f51ce
DiseaseDiGeorge syndrome (is_implicated_in)

DVL1P1 DVL1

9.97e-065302DOID:11198 (is_implicated_in)
Diseaseseborrheic dermatitis

PRICKLE2 TNRC18

1.88e-0420302EFO_1000764
DiseaseC-reactive protein measurement

KDM2B AHI1-DT KLF10 ZNF608 SCAF4 DNAH11

1.18e-031206306EFO_0004458
Diseaselung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma

DVL1P1 DVL1

1.28e-0352302EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Diseasenicotine dependence

DVL1P1 DVL1

2.86e-0378302EFO_0003768
Diseasehippocampal volume

DYNC2I1 AHI1-DT DNAH11

3.35e-03297303EFO_0005035
DiseaseS-6-hydroxywarfarin measurement

DYNC2I1 ING2 SRRM4

6.09e-03368303EFO_0803326
Diseaseneurodegenerative disease (implicated_via_orthology)

DVL1P1 DVL1

9.53e-03145302DOID:1289 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
RCTQQLRRDSDHRER

ERVK-19

656

O71037
RCTQQLRRDSDHRER

ERVK-8

656

Q902F8
RCVLPPRREHRREAA

DNAH11

846

Q96DT5
LRRRSHGDRCVPRSR

AHI1-DT

121

P0C7V0
CFAPRCRERRRNERL

CD80

266

P33681
RCRDPDQDARSRDRV

DYNC2I1

56

Q8WVS4
RCTQQLRRDSDHRER

ERVK-7

1416

P63135
RPRRQRTSESRDLCH

ING2

151

Q9H160
RRATSRDDNRRFRPH

PRICKLE2

671

Q7Z3G6
RRSECEEAPRRRSDE

KDM2B

766

Q8NHM5
TCRAEAPRDRDRDRD

CBX8

141

Q9HC52
EDRSHRRDEERPRRL

EIF3A

926

Q14152
RCTQQLRRDSDHRER

ERVK-6

656

Q69384
CERRFARSDELSRHR

KLF10

406

Q13118
VSHRRERARRRNREE

DVL1

141

O14640
RCTQQLRRDSDHRER

HERVK_113

656

Q902F9
VSHRRDRARRRNREE

DVL1P1

141

P54792
RHSPRSRSQERRDRE

SCAF4

471

O95104
RSPDRDRHRDLEERN

SCAF4

1036

O95104
CRREEDERPGRACRR

RTP5

521

Q14D33
REDHPRRGREDRQHR

SNIP1

111

Q8TAD8
SRRPRRDAAERCAAA

LRRC41

286

Q15345
HRSRSDRREQRAAAP

NHS

241

Q6T4R5
CDRLSAVRSPRRREA

FBXL22

116

Q6P050
NREEERRRRVSHDPF

RIPK1

406

Q13546
RRRDSEDRREEPHRS

TNRC18

1506

O15417
VHRRARRERDSDGDR

ZNF516

536

Q92618
HRHRRRRTCPRERDR

USP42

976

Q9H9J4
RRTCPRERDRQDRHA

USP42

981

Q9H9J4
ERGRPHERARSRERD

TJP2

176

Q9UDY2
ETRAAVRRCRRSHPA

PRAF2

86

O60831
PDHRRTRARAERSRS

RLIM

216

Q9NVW2
PEEGQKSRRRHSRRC

SRRM4

211

A7MD48
APRTRAVRNVRRHAC

XPO5

591

Q9HAV4
AARRRRPERQESAEH

SPTBN4

2261

Q9H254
REREAERERDRHSPF

ZNF608

1441

Q9ULD9
SFERRHGERDRRDNR

ZC3H13

621

Q5T200