Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionCTP synthase activity

CTPS2 CTPS1

1.39e-052752GO:0003883
GeneOntologyBiologicalProcess'de novo' CTP biosynthetic process

CTPS2 CTPS1

1.34e-052762GO:0044210
GeneOntologyBiologicalProcessgalactosylceramide catabolic process

GALC PSAP

4.01e-053762GO:0006683
GeneOntologyBiologicalProcessventral spinal cord development

DBX1 GIGYF2 LHX3 TBX20

5.80e-0557764GO:0021517
GeneOntologyBiologicalProcesspyrimidine nucleobase metabolic process

TET2 CTPS2 CTPS1

7.04e-0522763GO:0006206
GeneOntologyBiologicalProcessgalactolipid catabolic process

GALC PSAP

8.00e-054762GO:0019376
GeneOntologyBiologicalProcesscell differentiation in spinal cord

DBX1 GIGYF2 LHX3 TBX20

8.60e-0563764GO:0021515
GeneOntologyBiologicalProcesspositive regulation of membrane potential

NDUFC2-KCTD14 ANK3 NDUFC2

1.04e-0425763GO:0045838
GeneOntologyBiologicalProcessresponse to ionomycin

PLCB1 CDK4

1.99e-046762GO:1904636
GeneOntologyBiologicalProcesscellular response to ionomycin

PLCB1 CDK4

1.99e-046762GO:1904637
GeneOntologyBiologicalProcessdirect ossification

MMP2 AXIN2

2.78e-047762GO:0036072
GeneOntologyBiologicalProcessintramembranous ossification

MMP2 AXIN2

2.78e-047762GO:0001957
GeneOntologyBiologicalProcesscell fate specification involved in pattern specification

DBX1 LHX3

3.70e-048762GO:0060573
GeneOntologyBiologicalProcesscellular response to vasopressin

SCNN1A PLCB1

3.70e-048762GO:1904117
GeneOntologyBiologicalProcessresponse to vasopressin

SCNN1A PLCB1

3.70e-048762GO:1904116
GeneOntologyBiologicalProcessventral spinal cord interneuron specification

DBX1 LHX3

3.70e-048762GO:0021521
GeneOntologyBiologicalProcesspyrimidine nucleobase biosynthetic process

CTPS2 CTPS1

3.70e-048762GO:0019856
GeneOntologyCellularComponentcytoophidium

CTPS2 CTPS1

3.80e-053752GO:0097268
HumanPhenoHyperesthesia

GALC PSAP UNC80

2.03e-059333HP:0100963
HumanPhenoDecorticate rigidity

GALC PSAP

4.07e-052332HP:0011444
HumanPhenoReduced brain glutamate level by MRS

GALC PSAP

4.07e-052332HP:0031161
HumanPhenoReduced tissue galactocerebrosidase activity

GALC PSAP

4.07e-052332HP:0034322
DomainNDUF_C2

NDUFC2-KCTD14 NDUFC2

1.63e-052762PF06374
DomainNADH-UbQ_OxRdtase_b14.5b_su

NDUFC2-KCTD14 NDUFC2

1.63e-052762IPR009423
DomainCTP_synthase_N

CTPS2 CTPS1

1.63e-052762IPR017456
DomainGATase1_CTP_Synthase

CTPS2 CTPS1

1.63e-052762IPR033828
DomainCTP_synthase

CTPS2 CTPS1

1.63e-052762IPR004468
DomainCTP_synth_N

CTPS2 CTPS1

1.63e-052762PF06418
DomainTFIID-31

TAF9B TAF9

4.89e-053762IPR003162
DomainTFIID-31kDa

TAF9B TAF9

4.89e-053762PF02291
Domain-

MMP21 MMP2

9.75e-0547621.10.101.10
DomainGATase

CTPS2 CTPS1

1.62e-045762PF00117
DomainGATASE

CTPS2 CTPS1

2.43e-046762IPR017926
DomainGATASE_TYPE_1

CTPS2 CTPS1

2.43e-046762PS51273
DomainSH3

DLG5 SH3PXD2B EFS DLG2 SH3D21 ARHGEF6

2.49e-04216766SM00326
DomainSH3

DLG5 SH3PXD2B EFS DLG2 SH3D21 ARHGEF6

2.49e-04216766PS50002
DomainSH3_domain

DLG5 SH3PXD2B EFS DLG2 SH3D21 ARHGEF6

2.74e-04220766IPR001452
DomainSH3_2

SH3PXD2B DLG2 SH3D21 ARHGEF6

4.18e-0486764IPR011511
DomainSH3_2

SH3PXD2B DLG2 SH3D21 ARHGEF6

4.18e-0486764PF07653
Domain-

CTPS2 CTPS1

7.20e-04107623.40.50.880
DomainClass_I_gatase-like

CTPS2 CTPS1

1.05e-0312762IPR029062
DomainPG_binding_1

MMP21 MMP2

2.96e-0320762PF01471
DomainPeptidoglycan-bd-like

MMP21 MMP2

2.96e-0320762IPR002477
DomainHemopexin-like_dom

MMP21 MMP2

3.91e-0323762IPR000585
DomainHemopexin-like_repeat

MMP21 MMP2

3.91e-0323762IPR018487
DomainGUANYLATE_KINASE_2

DLG5 DLG2

3.91e-0323762PS50052
DomainGUANYLATE_KINASE_1

DLG5 DLG2

3.91e-0323762PS00856
DomainM10A_MMP

MMP21 MMP2

3.91e-0323762IPR033739
DomainHemopexin

MMP21 MMP2

3.91e-0323762PF00045
DomainHEMOPEXIN

MMP21 MMP2

3.91e-0323762PS00024
Domain-

MMP21 MMP2

3.91e-03237622.110.10.10
DomainHEMOPEXIN_2

MMP21 MMP2

3.91e-0323762PS51642
DomainHX

MMP21 MMP2

3.91e-0323762SM00120
DomainPept_M10A

MMP21 MMP2

3.91e-0323762IPR021190
DomainPeptidase_M10

MMP21 MMP2

4.26e-0324762PF00413
DomainIQ

UBE3B PPEF2 MYO16

4.40e-0381763SM00015
DomainSH3_1

SH3PXD2B EFS DLG2 ARHGEF6

4.50e-03164764PF00018
DomainGuanylate_kin

DLG5 DLG2

4.99e-0326762PF00625
DomainGK/Ca_channel_bsu

DLG5 DLG2

4.99e-0326762IPR008145
DomainGuanylate_kin-like_dom

DLG5 DLG2

4.99e-0326762IPR008144
DomainGuKc

DLG5 DLG2

4.99e-0326762SM00072
DomainIQ_motif_EF-hand-BS

UBE3B PPEF2 MYO16

5.90e-0390763IPR000048
DomainZnMc

MMP21 MMP2

6.18e-0329762SM00235
DomainPeptidase_Metallo

MMP21 MMP2

6.18e-0329762IPR006026
DomainIQ

UBE3B PPEF2 MYO16

6.46e-0393763PS50096
Pubmed

Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.

RINT1 ZBTB32 RNF31 TRIP6 EFS DLG2 SPAG8 MTUS2

3.12e-0640277824722188
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SH3PXD2B ANK3 TAF9B TRIP6 RBM26 GIGYF2 CTPS1 SRCAP UBN2

3.55e-0654977938280479
Pubmed

Expression of ECM1 and MMP-2 in follicular thyroid lesions among Egyptians.

MMP2 ECM1

4.84e-06277225812648
Pubmed

A mutation in the saposin A domain of the sphingolipid activator protein (prosaposin) gene results in a late-onset, chronic form of globoid cell leukodystrophy in the mouse.

GALC PSAP

4.84e-06277211371512
Pubmed

Comparative clinico-pathological study of saposin-A-deficient (SAP-A-/-) and Twitcher mice.

GALC PSAP

4.84e-06277215290897
Pubmed

Genetic ablation of Saposin-D in Krabbe disease eliminates psychosine accumulation but does not significantly improve demyelination.

GALC PSAP

4.84e-06277237337846
Pubmed

In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.

TAF9B TAF9

4.84e-06277212837753
Pubmed

TET2-mediated ECM1 hypomethylation promotes the neovascularization in active proliferative diabetic retinopathy.

TET2 ECM1

4.84e-06277238172938
Pubmed

NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.

NDUFC2-KCTD14 NDUFC2

4.84e-06277237506315
Pubmed

BCL6 locus is hypermethylated in angioimmunoblastic T-cell lymphoma.

TET2 BCL6

4.84e-06277227921272
Pubmed

Regulation of human cytidine triphosphate synthetase 2 by phosphorylation.

CTPS2 CTPS1

4.84e-06277220739275
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

RINT1 ZBTB32 PSAP RNF31 TRIP6 NUTM2B SPAG8 TAF9 ECM1

8.06e-0660877916713569
Pubmed

The contribution of de novo coding mutations to autism spectrum disorder.

GIGYF2 SRCAP UBN2

8.31e-061877325363768
Pubmed

Human transcription factor protein interaction networks.

TET2 TFPT TAF9B KHDRBS1 TRIP6 GIGYF2 ZNF217 ASXL2 LHX3 SRCAP TAF9 UBN2 DHX30

1.43e-051429771335140242
Pubmed

Mutations in UNC80, Encoding Part of the UNC79-UNC80-NALCN Channel Complex, Cause Autosomal-Recessive Severe Infantile Encephalopathy.

UNC79 UNC80

1.45e-05377226708753
Pubmed

Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A.

CTPS2 CTPS1

1.45e-05377216179339
Pubmed

Nuclear PLCbeta1 is required for 3T3-L1 adipocyte differentiation and regulates expression of the cyclin D3-cdk4 complex.

PLCB1 CDK4

1.45e-05377219385066
Pubmed

Genetic variants in components of the NALCN-UNC80-UNC79 ion channel complex cause a broad clinical phenotype (NALCN channelopathies).

UNC79 UNC80

1.45e-05377230167850
Pubmed

Human TAFII31 protein is a transcriptional coactivator of the p53 protein.

TAF9B TAF9

1.45e-0537727761466
Pubmed

Aldosterone reprograms promoter methylation to regulate αENaC transcription in the collecting duct.

TET2 SCNN1A

1.45e-05377223926181
Pubmed

Extracellular calcium controls background current and neuronal excitability via an UNC79-UNC80-NALCN cation channel complex.

UNC79 UNC80

1.45e-05377221040849
Pubmed

Intellectual disability-associated UNC80 mutations reveal inter-subunit interaction and dendritic function of the NALCN channel complex.

UNC79 UNC80

1.45e-05377232620897
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

DLG5 STOX2 ANK3 KHDRBS1 TRIP6 GIGYF2

2.67e-0526377634702444
Pubmed

TEAD1, MYO7A and NDUFC2 are novel functional genes associated with glucose metabolism in BXD recombinant inbred population.

NDUFC2-KCTD14 NDUFC2

2.89e-05477238385898
Pubmed

The Multimerization State of the Amyloid-β42 Amyloid Peptide Governs its Interaction Network with the Extracellular Matrix.

MMP2 PCOLCE

2.89e-05477228106549
Pubmed

The NALCN channel complex is voltage sensitive and directly modulated by extracellular calcium.

UNC79 UNC80

2.89e-05477232494638
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TET2 TAF9B RBM26 ZNF217 BCL6 UBN2

2.97e-0526877633640491
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

KHDRBS1 EFS RBM26 DLG2 CPLANE1 ECM1 MTUS2 AXIN2

3.41e-0556077821653829
Pubmed

Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains.

DBX1 LHX3 AXIN2

3.66e-052977330177510
Pubmed

Editing of CD1d-bound lipid antigens by endosomal lipid transfer proteins.

GALC PSAP

4.82e-05577214684827
Pubmed

A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins.

UNC79 BAHCC1

4.82e-05577216807365
Pubmed

Inactivation of cytidine triphosphate synthase 1 prevents fatal auto-immunity in mice.

CTPS2 CTPS1

7.22e-05677238438357
Pubmed

A peptide aptamer to antagonize BCL-6 function.

BCL6 CDK4

7.22e-05677216331266
Pubmed

Identification of binding partners interacting with the α1-N-propeptide of type V collagen.

MMP2 PCOLCE

1.01e-04777220979576
Pubmed

Expression of Tbx2 and Tbx3 in the developing hypothalamic-pituitary axis.

LHX3 TBX20

1.01e-04777218534921
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 JCAD DLG5 STOX2 SH3PXD2B TRIP6 GIGYF2 TRAPPC14 PRAG1

1.20e-0486177936931259
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

STOX2 SH3PXD2B NYAP2 PRAG1 MYO16

1.27e-0421877533378226
Pubmed

Interaction network of human early embryonic transcription factors.

TET2 PSAP ZNF217 ASXL2 UBN2 BAHCC1

1.31e-0435177638297188
Pubmed

Polarity protein complex Scribble/Lgl/Dlg and epithelial cell barriers.

DLG5 DLG2

1.34e-04877223397623
Pubmed

Energy deprivation and a deficiency in downstream metabolic target genes during the onset of embryonic heart failure in RXRalpha-/- embryos.

NDUFC2-KCTD14 NDUFC2

1.34e-0487729425147
Pubmed

Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity.

EFS HELT AXIN2

1.58e-044777328219675
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

HIVEP3 SH3PXD2B PTPRF UBE3B SRCAP PRAG1 PRRT4 MYORG DHX30 BAHCC1

1.60e-041105771035748872
Pubmed

TAF9b (formerly TAF9L) is a bona fide TAF that has unique and overlapping roles with TAF9.

TAF9B TAF9

1.72e-04977215899866
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

TFPT TAF9B RNF31 TRIP6 BTBD18 MMP21 SRCAP TAF9 UNC80 BAHCC1

1.74e-041116771031753913
Pubmed

The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.

TAF9B TAF9 AXIN2

2.13e-045277328893950
Pubmed

CTPS and IMPDH form cytoophidia in developmental thymocytes.

CTPS2 CTPS1

2.15e-041077234022203
Pubmed

Wnt/β-catenin signaling is disrupted in the extra-toes (Gli3(Xt/Xt) ) mutant from early stages of forebrain development, concomitant with anterior neural plate patterning defects.

DBX1 AXIN2

2.63e-041177221452227
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

STOX2 SH3PXD2B NYAP2 ANK3 PLCB1 GIGYF2 DLG2 UBN2 UNC79

2.76e-0496377928671696
Pubmed

De novo genic mutations among a Chinese autism spectrum disorder cohort.

HIVEP3 GIGYF2

3.15e-041277227824329
Pubmed

Functional proteomics mapping of a human signaling pathway.

PSAP PTPRF ANK3 KHDRBS1 VPS41 ASXL2 DHX30

3.40e-0459177715231748
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

JCAD KHDRBS1 GIGYF2 CTPS1 DHX30

3.64e-0427477534244482
Pubmed

Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties.

TBX20 AXIN2

3.71e-041377225599332
Pubmed

Hoxb3 negatively regulates Hoxb1 expression in mouse hindbrain patterning.

LHX3 TBX20

4.33e-041477221320481
Pubmed

Whole genome sequencing resource identifies 18 new candidate genes for autism spectrum disorder.

SRCAP UBN2

4.33e-041477228263302
Pubmed

Interactions between the otitis media gene, Fbxo11, and p53 in the mouse embryonic lung.

MMP2 BCL6

4.33e-041477226471094
Pubmed

Inactivation of LAR family phosphatase genes Ptprs and Ptprf causes craniofacial malformations resembling Pierre-Robin sequence.

PTPRF AXIN2

4.99e-041577223863482
Pubmed

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.

RBM26 ECM1

5.69e-041677220014019
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

TFPT GALC ANK3 UBE3B DACT3 GIGYF2 PCARE ARHGEF6 CDK4 DHX30

6.57e-041321771027173435
Pubmed

An inter-species protein-protein interaction network across vast evolutionary distance.

TFPT ZBTB32 CTPS2 TRIP6 EFS MTUS2

7.17e-0448377627107014
Pubmed

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

TAF9B TAF9

7.23e-041877229111974
Pubmed

The transcription factors Nkx2.2 and Nkx2.9 play a novel role in floor plate development and commissural axon guidance.

DBX1 LHX3

7.23e-041877221068056
Pubmed

Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation.

HIVEP3 CDK4

7.23e-041877226091038
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

DLG5 RNF31 CTPS1 DHX30

7.29e-0418277431067453
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

DLG5 TRIP6 GIGYF2 ZNF217

7.59e-0418477432908313
Pubmed

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.

AXIN2 CDK4

8.07e-041977217596282
Pubmed

Different levels of repressor activity assign redundant and specific roles to Nkx6 genes in motor neuron and interneuron specification.

DBX1 LHX3

8.07e-041977211567614
Pubmed

Cytoplasmic ATXN7L3B Interferes with Nuclear Functions of the SAGA Deubiquitinase Module.

TAF9B TAF9

8.96e-042077227601583
Pubmed

Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.

TAF9B TAF9

8.96e-042077217884155
Pubmed

Agrin has a pathological role in the progression of oral cancer.

DLG5 ANK3 RNF31 PCOLCE

9.78e-0419777429872149
Pubmed

Mammalian embryo comparison identifies novel pluripotency genes associated with the naïve or primed state.

PSAP TRIP6

9.89e-042177230026265
Pubmed

T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration.

LHX3 TBX20

9.89e-042177217119020
Pubmed

Erg is a crucial regulator of endocardial-mesenchymal transformation during cardiac valve morphogenesis.

MMP2 TBX20

9.89e-042177222932696
Pubmed

Differential expression of a set of genes in follicular and classic variants of papillary thyroid carcinoma.

BCL6 NDUFC2

9.89e-042177221509594
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

HIVEP3 PTPRF CDK4

1.07e-039077315033168
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP21 MMP2

1.09e-032277223421805
Pubmed

Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy.

BCL6 AXIN2

1.09e-032277228334989
Pubmed

NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons.

NYAP2 MYO16

1.09e-032277221946561
Pubmed

An expanded Oct4 interaction network: implications for stem cell biology, development, and disease.

ZNF217 UBN2 DNMT3L

1.10e-039177320362542
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

TET2 RNF31 KHDRBS1 TRIP6 ZNF217

1.14e-0335377527545878
Pubmed

Beta-catenin regulates Cripto- and Wnt3-dependent gene expression programs in mouse axis and mesoderm formation.

GPR137B AXIN2

1.19e-032377214623818
Pubmed

Heterozygous Vangl2Looptail mice reveal novel roles for the planar cell polarity pathway in adult lung homeostasis and repair.

MMP2 AXIN2

1.29e-032477228237967
Pubmed

Sall4 regulates neuromesodermal progenitors and their descendants during body elongation in mouse embryos.

DBX1 AXIN2

1.29e-032477231235634
Pubmed

Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.

DBX1 HELT

1.29e-032477224335253
Pubmed

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary.

AXIN2 DNMT3L

1.29e-032477221991325
Pubmed

miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2.

AXIN2 CDK4

1.40e-032577222564414
Pubmed

The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling.

TBX20 CDK4

1.40e-032577233846290
Pubmed

β-Catenin signaling specifies progenitor cell identity in parallel with Shh signaling in the developing mammalian thalamus.

HELT AXIN2

1.40e-032577222745311
Pubmed

Wnt signaling determines ventral spinal cord cell fates in a time-dependent manner.

LHX3 AXIN2

1.40e-032577218927156
Pubmed

A crucial role for primary cilia in cortical morphogenesis.

DBX1 AXIN2

1.40e-032577219036983
Pubmed

Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.

VPS41 GPR137B

1.40e-032577211110696
Pubmed

A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development.

DBX1 AXIN2

1.40e-032577232840212
Pubmed

Proteomics characterization of extracellular space components in the human aorta.

PSAP MMP2 PCOLCE

1.49e-0310177320551380
Pubmed

APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.

TBX20 AXIN2

1.52e-032677226493106
Pubmed

Angiopoietin-like 2 is essential to aortic valve development in mice.

MMP2 AXIN2

1.52e-032677236414704
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

JCAD NYAP2 BAHCC1

1.57e-0310377310819331
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

JCAD DLG5 SH3PXD2B ANK3 TRIP6 GIGYF2

1.60e-0356577625468996
Pubmed

Tbx20 acts upstream of Wnt signaling to regulate endocardial cushion formation and valve remodeling during mouse cardiogenesis.

MMP2 TBX20

1.64e-032777223824573
Pubmed

Lamination of the cerebral cortex is disturbed in Gli3 mutant mice.

DBX1 AXIN2

1.64e-032777218448089
Pubmed

Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph.

SCNN1A MMP2 BCL6 CDK4

1.76e-0323177421048031
Pubmed

The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion.

SCNN1A AXIN2

1.76e-032877229212953
Cytoband11q14.1

NDUFC2-KCTD14 DLG2 NDUFC2

4.97e-054277311q14.1
Cytoband13q31.1

RBM26 SLITRK6

5.17e-042077213q31.1
CytobandEnsembl 112 genes in cytogenetic band chr7q22

RINT1 TRIP6 TRAPPC14 PCOLCE

5.19e-04219774chr7q22
Cytoband1p34

HIVEP3 PTPRF

1.33e-03327721p34
CytobandEnsembl 112 genes in cytogenetic band chr1p34

HIVEP3 PTPRF CTPS1 SH3D21

1.54e-03294774chr1p34
Cytoband4q35.1

STOX2 HELT

1.69e-03367724q35.1
Cytoband7q22

TRIP6 PCOLCE

1.88e-03387727q22
CytobandEnsembl 112 genes in cytogenetic band chr11q14

NDUFC2-KCTD14 DLG2 NDUFC2

2.34e-03156773chr11q14
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP21 MMP2

1.15e-0324382891
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

DLG5 DLG2

1.35e-0326382904
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB32 BTBD18 BCL6

2.78e-03134383861
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

RBM26 DLG2 MYO16

6.44e-03181383694
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16B PSAP PTPRF RBM26 UBN2 UNC80

9.11e-07188776a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

HIVEP3 CRACD SH3PXD2B ANK3 DLG2 MMP2

1.20e-06197776f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellICU-SEP-Lymphocyte-T_NK-dnT|ICU-SEP / Disease, Lineage and Cell Type

ZBTB32 CTPS2 DACT3 DLG2 BAHCC1

1.03e-0516677596d92316cee20b722fe782db9dafcceb8f2c220b
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD STOX2 TRIP6 PPEF2 BAHCC1

1.09e-051687752e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STOX2 SCNN1A DLG2 MYO16 PCOLCE

1.40e-05177775b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HIVEP3 DACT3 DLG2 MYO16 PCOLCE

1.52e-0518077508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRF ANK3 SLITRK6 UNC80 AXIN2

1.60e-051827756fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B MMP2 TBX20 ECM1 PCOLCE

1.60e-05182775f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellMild/Remission-B_intermediate-10|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ZBTB32 PSAP ANK3 GPR137B PRAG1

1.64e-05183775278064c9f0582463b83bf156d34e77f60187613b
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B MMP2 TBX20 ECM1 PCOLCE

1.78e-0518677535c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SH3PXD2B MMP2 TBX20 ECM1 PCOLCE

1.78e-05186775d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

STOX2 NYAP2 PTPRF SCNN1A MYO16

1.82e-0518777577f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD NYAP2 BCL6 SLITRK6 MYO16

1.92e-05189775f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EFS DLG2 MMP2 SLITRK6 PCOLCE

1.92e-05189775eccf3d49354a67c94f1ed7c15a98a48a5e8e2ed0
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EFS DLG2 MMP2 SLITRK6 PCOLCE

1.92e-0518977540764f461b8aa1d3a2c5a30590b7fb9307d47d09
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STOX2 VPS41 PLCB1 DNAI4 BCL6

2.02e-05191775d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCelldroplet-Heart-nan-24m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT3 MMP2 TBX20 ECM1 PCOLCE

2.02e-051917751f660ea2841324d13f63e01f1789e606c2843fc4
ToppCell10x5'v1-week_14-16-Mesenchymal_fibro-stroma-endosteal_fibroblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EFS DLG2 MMP2 SLITRK6 PCOLCE

2.02e-0519177544b1f62fdee03b157fe545f2ae6ff84f8929a8ac
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PSAP ARHGAP30 MMP2 SLITRK6 PCOLCE

2.07e-051927758171a60df481195c39a7f740effcae8e4deb6ca7
ToppCellfacs-Lung-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 PTPRF ANK3 SCNN1A SPAG8

2.07e-05192775ebfd8209a7353fbccb8ca7ade14b4f25822cebd2
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP2 TBX20 ECM1 MYORG PCOLCE

2.12e-05193775735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT3 MMP2 TBX20 ECM1 PCOLCE

2.12e-051937750ca0439dfdcb2361ca8d1015fb874a5b5c635d31
ToppCellfacs-Heart-RV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP2 TBX20 ECM1 MYORG PCOLCE

2.12e-0519377576f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCelldroplet-Heart-nan-24m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DACT3 MMP2 TBX20 ECM1 PCOLCE

2.12e-05193775d08919db9601941569b9a143dad4d8e6f56a4389
ToppCellfacs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMP2 TBX20 ECM1 MYORG PCOLCE

2.12e-05193775ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC16B TRIP6 DACT3 MMP2 PCOLCE

2.17e-051947757826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SH3PXD2B EFS MMP2 MYORG PCOLCE

2.17e-05194775292ce9021678534c9eedb367b9772a9d976208a8
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

STOX2 NYAP2 PTPRF SCNN1A MYO16

2.23e-05195775a71ba5e4043e2d35a45a2c60a96b087e31832345
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

STOX2 PTPRF ANK3 SCNN1A DLG2

2.23e-051957759406866f99555198a9be311fbd65751b70f35446
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK3 PLCB1 UNC79 MTUS2 UNC80

2.40e-051987750ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD MMP21 MMP2 AXIN2 PCOLCE

2.46e-05199775dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

HIVEP3 MMP2 BCL6 MYO16 PCOLCE

2.46e-051997758b86c69aaf60feff53aa782559cfece7342a23de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JCAD MMP21 MMP2 AXIN2 PCOLCE

2.46e-05199775c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANK3 EFS MMP2 SLITRK6 PCOLCE

2.52e-05200775747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCell5'-Adult-Distal_Rectal-Mesenchymal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH3PXD2B PSAP MMP2 ECM1 PCOLCE

2.52e-05200775db6281b5d4032116310db379d9175d790994c99c
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DLG5 PTPRF ANK3 SCNN1A CPLANE1

2.52e-0520077597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons|GW26 / Sample Type, Dataset, Time_group, and Cell type.

HIVEP3 CRACD NYAP2 ANK3 UBN2

2.52e-05200775bad32a95b759fad509401b07bc96a56687c2a592
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

ANK3 PLCB1 UNC79 MTUS2 UNC80

2.52e-0520077548d801219bc771d6c7e151dc88ca4c179988de85
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

CRACD NYAP2 BCL6 SLITRK6 MYO16

2.52e-05200775862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

CRACD NYAP2 BCL6 SLITRK6 MYO16

2.52e-05200775a91345f268f13170c27309333603eb82400c9947
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH3PXD2B PSAP MMP2 ECM1 PCOLCE

2.52e-0520077510f0c20ba7c71d9e2e177597f85b41cb40f0d878
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ANK3 EFS MMP2 SLITRK6 PCOLCE

2.52e-05200775de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH3PXD2B PSAP MMP2 ECM1 PCOLCE

2.52e-05200775a2bb67a06757f19be3f56f8cb5bb7e2affa5f4ed
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

CRACD NYAP2 BCL6 SLITRK6 MYO16

2.52e-05200775d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DLG5 PTPRF ANK3 SCNN1A CPLANE1

2.52e-05200775ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMP2 SLITRK6 ECM1 MYO16 PCOLCE

2.52e-05200775ac8a5d71acd4d401995babd233f0d3738e8ad2a5
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NYAP2 EFS PLCB1 DNMT3L

7.88e-0513177472340ea139a6616a466b417949e273f473fba993
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

DRC7 PRR22 BCL6 SPAG8

1.14e-0414477408005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

JCAD SCNN1A UNC79 SH3D21

1.58e-04157774f6210be2362d833c6d869ff921188bfc85dda11d
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

JCAD SCNN1A UNC79 SH3D21

1.58e-0415777443a6b423fd70479822a564ff4225a1e4951ae5ed
ToppCellControl-Lymphocyte-T_NK-dnT|Control / Disease, Lineage and Cell Type

ZBTB32 GPR137B DNAI4 MYO16

1.62e-041587747a2fad6426549d910834debfe5e102fe2ab5976d
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDUFC2-KCTD14 ZBTB32 SCNN1A PCARE

1.70e-041607740293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDUFC2-KCTD14 ZBTB32 SCNN1A PCARE

1.70e-041607743eaae86fa08f7651021316f8e5811bf48055591e
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TAF9B BCL6 CPLANE1 UBN2

1.70e-0416077470f3637dd0bcfcef421aa114f946fff0048f192e
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 HELT PLCB1 SH3D21

1.74e-041617744bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRF ANK3 SCNN1A MYO16

1.79e-0416277406f5d6c0bb26fe9d5180bc2ebf2c54bf52e715f3
ToppCellControl-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PSAP ANK3 GPR137B PRAG1

1.79e-04162774aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PTPRF ANK3 SCNN1A MYO16

1.79e-04162774d0d9c18a73bc0bf4f38308ef2eee8ae20f6a7918
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 PLCB1 PRAG1 MTUS2

1.79e-04162774373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

PTPRF UBE3B GIGYF2 CPLANE1

1.96e-0416677432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

EFS MMP2 SLITRK6 CDK4

1.96e-04166774a7ac5a414e3e2ff01f1c452c0a85048b17cba0b6
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSAP RBM26 PPEF2 UBN2

1.96e-0416677466026988509e39e41274fa0de738383219e8ff30
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TFPT EFS DACT3 UBN2

1.96e-04166774c11dcf9705b85ac3da6ae86358f5ffd64ae8327e
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRF TAF9B SCNN1A MYO16

2.01e-04167774bebc2493a2ee41920b21c2b774a1c5a9619315c4
ToppCellfacs-Lung-3m-Epithelial-alveolar_epithelial-type_I_pneumocyte-type_1_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRF TAF9B SCNN1A MYO16

2.01e-041677749f2661729a2d58e17a9203a563d538c08a3dbbbc
ToppCellPosterior_cortex-Neuronal-Inhibitory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

CRACD PRRT4 MYO16 ARHGEF6

2.01e-041677749a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

SH3PXD2B DLG2 MMP2 PCOLCE

2.05e-04168774aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG2 PRR22 AXIN2 DNMT3L

2.05e-04168774260c768468dff51888f7a68e5424bb174dbaa759
ToppCellfacs-Marrow-T_cells-18m-Myeloid-granulocyte_monocyte_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG2 PRR22 AXIN2 DNMT3L

2.05e-0416877418d7719a76620d5e5698f9ffd08b4ad4cb7c13f8
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NYAP2 ZBTB32 UNC79 UNC80

2.10e-0416977496a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 SCNN1A DNAI4 MYO16

2.15e-04170774b535baeb4dbd644051cf992babb61add9eaae4e3
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 SCNN1A DNAI4 MYO16

2.15e-041707742477c9f29dbe27f172df699003971e828d6ab8c9
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

CRACD LHX3 PRRT4 BAHCC1

2.25e-04172774a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

MMP2 SLITRK6 ECM1 PCOLCE

2.45e-04176774852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

MMP2 SLITRK6 ECM1 PCOLCE

2.45e-04176774d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 DNAI4 SLITRK6 SPAG8

2.50e-041777743cfde67b93f3986312f5e74e42504214d966e7dc
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DRC7 DNAI4 SLITRK6 SPAG8

2.50e-0417777412a52a12a87a31e501ced611f46a90d172ca7e35
ToppCellSevere-B_intermediate-10|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PSAP ANK3 GPR137B PRAG1

2.56e-04178774b7374a97c51239782bed658381a02cb1b3d9bf66
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

SH3PXD2B DACT3 MMP2 ECM1

2.56e-04178774142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 DNAI4 SPAG8 PCOLCE

2.61e-041797749d7e39357b269d30ff1e8007a91f8645f3d80e73
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 ANK3 SCNN1A BCL6

2.61e-041797746e965e424eebef50f0202cff75f458be395cfca1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 DNAI4 SPAG8 PCOLCE

2.61e-041797741611e11f5f74432627e2f57a27e352b1e46be618
ToppCellfacs-Kidney-nan-24m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EFS MMP2 ECM1 UNC79

2.67e-04180774f9f8245cbcdea18c15e2976c85b72c6807309787
ToppCellfacs-Trachea-nan-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DRC7 DNAI4 SLITRK6 SPAG8

2.67e-04180774cf6e9f757afeb342c5023f6e6152a1b4d0d164b4
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DACT3 DLG2 MYO16 PCOLCE

2.67e-041807749b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 PSAP PTPRF GPR137B

2.73e-04181774782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HIVEP3 PSAP PTPRF GPR137B

2.73e-04181774e2481291c236105774c53883e6f20da11941df9b
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NYAP2 EFS MMP2 PCOLCE

2.78e-04182774bb7de0c93d8f59f13c990e425139b9348ca8027e
ToppCellcellseq-Mesenchymal-Chondrocytic-Mesenchymal_Airway/Vascular-Chondrocyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NYAP2 EFS MMP2 PCOLCE

2.78e-04182774507f095af4dff60f2c2b64d750477154084c3595
ToppCellcellseq-Mesenchymal-Chondrocytic|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NYAP2 EFS MMP2 PCOLCE

2.78e-0418277488bd17c07bd8443a0ede4e9dc7bc9d1230b42211
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

HIVEP3 PLCB1 PRAG1 MTUS2

2.78e-04182774a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

DRC7 DNAI4 SLITRK6 SPAG8

2.78e-04182774e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CRACD HELT ECM1 MYO16

2.78e-0418277408aff7112c9dac0ef5540300516a604782b21169
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACD CTPS2 EFS PLCB1

2.78e-04182774d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACD CTPS2 EFS PLCB1

2.78e-0418277492f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CRACD CTPS2 EFS PLCB1

2.78e-0418277402baca9a72c7b559c3e452693b3b134af804c868
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

STOX2 NYAP2 PTPRF SCNN1A

2.84e-041837747b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

PTPRF SCNN1A SRCAP MYO16

2.84e-0418377431fef35ecf30162662f24d335d8f0cceacc07039
ToppCell3'-Broncho-tracheal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GALC ZBTB32 MYO16 ARHGEF6

2.84e-041837748b7f9e55c21c99395c71c5ac4f5db0f6c5733ef9
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

STOX2 NYAP2 PTPRF SCNN1A

2.84e-04183774942530449e9c6583705eeb8f6f12621daea57252
DiseaseInfantile Globoid Cell Leukodystrophy

GALC PSAP

6.37e-062752C0751273
DiseaseKrabbe disease (implicated_via_orthology)

GALC PSAP

6.37e-062752DOID:10587 (implicated_via_orthology)
DiseaseNeurodevelopmental Disorders

HIVEP3 GIGYF2 SRCAP DHX30

9.47e-0593754C1535926
Diseasecolon adenoma (is_marker_for)

TET2 AXIN2

1.33e-047752DOID:0050912 (is_marker_for)
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GIGYF2 DLG2 SRCAP

2.67e-0449753DOID:0060037 (implicated_via_orthology)
DiseaseAbnormality of refraction

HIVEP3 JCAD PTPRF ANK3 DLG2 LHX3 MMP2 AXIN2

3.09e-04673758HP_0000539
Diseaseobesity

CRACD SEC16B NYAP2 SCNN1A PRAG1

3.78e-04241755EFO_0001073
Diseaseessential hypertension, age at diagnosis

TBX20 UNC79 BAHCC1

3.97e-0456753EFO_0004918, MONDO_0001134
Diseaseadverse effect, response to xenobiotic stimulus

SCNN1A PLCB1 BCL6

4.63e-0459753EFO_0009658, GO_0009410
Diseasemonocyte percentage of leukocytes

NYAP2 UBE3B BMF PLCB1 ARHGAP30 BCL6 MYO16 BAHCC1

5.34e-04731758EFO_0007989
Diseaseage at menarche

TET2 SEC16B ZBTB32 PLCB1 DLG2 UNC79 UNC80

7.87e-04594757EFO_0004703
Diseaseuridine diphosphate galactose measurement, uridine diphosphate glucose measurement

JCAD TBX20

8.46e-0417752EFO_0010543, EFO_0010544
Diseaseperitonsillar abscess

TET2 PRAG1

9.50e-0418752EFO_0007429
Diseasebody surface area

SEC16B GIGYF2 LHX3 BCL6 CTPS1 UNC79 AXIN2

1.24e-03643757EFO_0022196
DiseaseLeft Ventricle Remodeling

TBX20 AXIN2

1.30e-0321752C0600520
DiseaseVentricular Remodeling

TBX20 AXIN2

1.30e-0321752C0600519
Diseasetestosterone measurement

TET2 NYAP2 PTPRF ANK3 BMF PLCB1 CTPS1 SRCAP MYO16 ARHGEF6

1.41e-0312757510EFO_0004908
Diseasemonocyte count

HIVEP3 TET2 JCAD NYAP2 UBE3B BMF PLCB1 ARHGAP30 BCL6 MYO16

1.83e-0313207510EFO_0005091
Diseasecolon adenocarcinoma (is_marker_for)

TET2 MMP2

1.84e-0325752DOID:234 (is_marker_for)
DiseaseHematopoetic Myelodysplasia

TET2 PLCB1

2.48e-0329752C2713368

Protein segments in the cluster

PeptideGeneStartEntry
VPPPLASGLVLKYPI

C2orf16

1106

Q68DN1
PLPSPSYVHPALVGK

BAHCC1

2271

Q9P281
PAPPLRPSAALGYKE

ARHGEF6

596

Q15052
LLQYARPKPGSPRPF

DNMT3L

266

Q9UJW3
QYHSLLPPGGKLPPA

AXIN2

476

Q9Y2T1
GPLSDPITGKPYVPL

DHX30

391

Q7L2E3
LLLPPLQTPKLYGSP

ASXL2

1306

Q76L83
GYPKPLTSLGLPPDV

MMP2

551

P08253
LPKSGLRPPGYSRLP

MTUS2

831

Q5JR59
YLPPPEQPSSGSLKV

RBM26

81

Q5T8P6
LPSPPTGASLKFYVP

PCOLCE

371

Q15113
GAARSPALPYLPSAP

HELT

181

A6NFD8
LKYPVQPEGSSPLSP

MYO16

1526

Q9Y6X6
RPKFGRPLKPPSYSS

JCAD

286

Q9P266
YPKLISEGFPGIPSP

MMP21

436

Q8N119
LLAPPAGYPSLLRPT

DBX1

6

A6NMT0
PKIDYLLPGPGPAHS

DLG5

986

Q8TDM6
PPPKLTDPRLLYIGF

NDUFC2

21

O95298
SLPGPQPLLSSLVYP

LHX3

326

Q9UBR4
LTPLSLKRPPPYDAV

NYAP2

446

Q9P242
SPPSLYPSVDKHLLP

BTBD18

246

B2RXH4
LGRASAVPSGPPKYP

DACT3

431

Q96B18
SPPLSPALPKYKLAD

GIGYF2

26

Q6Y7W6
SFGLPLLYLPLKPPN

CPLANE1

2356

Q9H799
RTYLDKAPPPGLPAE

CDK4

101

P11802
TPPASPLSKLSRPYL

CRACD

971

Q6ZU35
LAALPPISYPRGALP

HOXD12

36

P35452
PDSLIAYIPGKPSPI

ANK3

3186

Q12955
PPSPDLIYKIPRASG

EFS

121

O43281
EPGPPIYAAPSNLKR

EFS

211

O43281
GYRLPLPASFPAVLP

BMF

101

Q96LC9
LKPAAPSARNAPYFP

BCL6

281

P41182
PLPDPLKPPSHLYSS

DRC7

161

Q8IY82
PRPLYHPDPLTGTAK

DNAI4

126

Q5VTH9
PSLKAPPARPVKGAY

KHDRBS1

421

Q07666
KTSLPPISPGRYSPI

DLG2

316

Q15700
VGYAAPPSPPLSRSL

ECM1

41

Q16610
TGRKGSYPLPPKSQP

GALC

471

P54803
ALTAPPPAYATLGPR

SCNN1A

636

P37088
PDSYTGPRLSFPLLP

PPEF2

111

O14830
APDLLPHKPLPASAY

PTPRF

1096

P10586
YTGLAPLYPKPQISP

PCARE

771

A6NGG8
PLYPKPQISPASGRE

PCARE

776

A6NGG8
SAYDDLSPLLGPKPP

ARHGAP30

611

Q7Z6I6
SLSPAEKTPYPGPGL

NUTM2B

826

A6NNL0
PTLTPAVPPYVKLGL

GPR137B

31

O60478
QTPLPLIKPYAGPRL

TAF9B

101

Q9HBM6
QTPLPLIKPYSGPRL

TAF9

101

Q16594
TPVPLSLGKLLPYEP

SPAG8

441

Q99932
PGPQRPPKLSSLAYD

SH3D21

41

A4FU49
PGLIPYITKPSTQLP

SLITRK6

311

Q9H5Y7
SRPIKPSPPYFGLLL

CTPS1

531

P17812
SLLKPLTVPPGYTFP

SRCAP

1126

Q6ZRS2
RPYASSLEKGPPKPG

RNF31

446

Q96EP0
PGSYLLEPQPYLKAP

PRR22

111

Q8IZ63
SRPMKPSPPYLGLLL

CTPS2

531

Q9NRF8
YRTGSLKPNPASPLP

TRIP6

131

Q15654
KPLMYRLPLSTPSPG

UBN2

976

Q6ZU65
DGLPLLHLSPYLSPP

UNC80

2656

Q8N2C7
RGPDKLLPYPTLASP

TFPT

236

P0C1Z6
PEKYSLPASPSVILP

RINT1

291

Q6NUQ1
SPVGRPLYLPPDKAV

TRAPPC14

546

Q8WVR3
SLLEPGKPPESLPSY

STOX2

571

Q9P2F5
PASYLKKNSGEPLPP

SH3PXD2B

271

A1X283
LLSSPYSMPPLPPSL

HIVEP3

1171

Q5T1R4
LPPYSLERKLSSPSP

PRRT4

261

C9JH25
PLLLYPQDGPRSKPQ

PSAP

176

P07602
DLPPLPALSLYSPGL

PRAG1

1286

Q86YV5
SPYLPRGDPVLKPLI

VPS41

446

P49754
LEKYPLESGVPLPSP

PLCB1

441

Q9NQ66
VLLPPPALKGAVPLY

SEC16B

1016

Q96JE7
PPPKLTDPRLLYIGF

NDUFC2-KCTD14

21

E9PQ53
RPPLLGFAYLKPPFS

UBE3B

981

Q7Z3V4
YPSQALPPKPRFLSS

ZNF217

961

O75362
LKGPPYSPLDISIFP

STRADB

281

Q9C0K7
MSLPPIRLPSPYGSD

ZBTB32

1

Q9Y2Y4
SLPPYSRLGMPLTPS

TBX20

386

Q9UMR3
YPSQDPLSKLSLPPI

TET2

1661

Q6N021
PSLSVALGDKPPPLY

UNC79

326

Q9P2D8
PYKPPAGRAAAPELS

MYORG

266

Q6NSJ0