Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	demethylase activity	KDM4C RIOX1 FBXL19 RSBN1 KDM4A FTO	1.76e-06	44	168	6	GO:0032451
GeneOntologyMolecularFunction	histone demethylase activity	KDM4C RIOX1 FBXL19 RSBN1 KDM4A	5.65e-06	31	168	5	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM4C RIOX1 FBXL19 RSBN1 KDM4A	6.65e-06	32	168	5	GO:0140457
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	TET2 KDM4C RIOX1 RSBN1 KDM4A FTO	1.78e-05	65	168	6	GO:0016706
GeneOntologyMolecularFunction	histone H3K36 demethylase activity	KDM4C RIOX1 KDM4A	9.19e-05	11	168	3	GO:0051864
GeneOntologyMolecularFunction	ATP hydrolysis activity	DDX59 KIF21A NVL CHD9 CHD2 CHD3 CHD4 ATP8B1 DNAH7 MACF1 ATP2B2 ATP2B4 MOV10	9.53e-05	441	168	13	GO:0016887
GeneOntologyMolecularFunction	dioxygenase activity	TET2 KDM4C RIOX1 RSBN1 KDM4A FTO	1.80e-04	98	168	6	GO:0051213
GeneOntologyMolecularFunction	ATP-dependent activity	DDX59 KIF21A NVL CHD9 CHD2 CHD3 CHD4 ATP8B1 DNAH7 DNAH14 MACF1 ATP2B2 ATP2B4 TOP2A MOV10	2.21e-04	614	168	15	GO:0140657
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD9 CHD2 CHD3 CHD4	2.57e-04	37	168	4	GO:0140658
GeneOntologyBiologicalProcess	microtubule-based movement	ADCY10 CFAP91 SPEF2 KIF21A PRSS55 APP DNAH7 DNAH14 MAPK8IP3 FSIP2 TEKT2 DST DLG2 DNAAF1 ATP2B4 ARHGAP21	2.50e-06	493	166	16	GO:0007018
GeneOntologyBiologicalProcess	microtubule-based process	ADCY10 CFAP91 SPEF2 KIF21A PRSS55 CHD3 MAP7 APP DNAH7 DNAH14 MAPK8IP3 FSIP2 TEKT2 DST SENP6 MACF1 DLG2 DNAAF1 ATP2B4 ARHGAP21 TBCD NLRP5	4.21e-05	1058	166	22	GO:0007017
GeneOntologyBiologicalProcess	neuron development	ADCY10 ARHGAP32 FOXO6 NEDD4L NCKAP1 MYCBP2 DBNL SPAG9 ATP8B1 APP EDN2 MAPK8IP3 ITPR1 NEDD4 TENM4 DST VASH2 PLXNA4 DIAPH2 MACF1 DLG2 AFDN ATP2B2 HES5 NOTCH2 MOV10 TBCD	4.27e-05	1463	166	27	GO:0048666
GeneOntologyBiologicalProcess	neuron projection extension	ADCY10 ARHGAP32 NEDD4L DBNL SPAG9 EDN2 PLXNA4 MACF1 AFDN	4.72e-05	207	166	9	GO:1990138
GeneOntologyBiologicalProcess	cilium movement	ADCY10 CFAP91 SPEF2 PRSS55 DNAH7 DNAH14 FSIP2 TEKT2 DNAAF1 ATP2B4	5.22e-05	261	166	10	GO:0003341
GeneOntologyBiologicalProcess	neuron projection morphogenesis	ADCY10 ARHGAP32 NEDD4L NCKAP1 MYCBP2 DBNL SPAG9 APP EDN2 MAPK8IP3 NEDD4 DST PLXNA4 DIAPH2 MACF1 AFDN NOTCH2 MOV10	8.52e-05	802	166	18	GO:0048812
GeneOntologyBiologicalProcess	cell morphogenesis	ADCY10 ARHGAP32 NEDD4L NCKAP1 MYCBP2 DBNL SPAG9 MAP7 APP BRWD3 EDN2 MAPK8IP3 ITPR1 NEDD4 DST PLXNA4 DIAPH2 MACF1 AFDN ATP2B2 NOTCH2 MOV10 TBCD	8.92e-05	1194	166	23	GO:0000902
GeneOntologyBiologicalProcess	plasma membrane bounded cell projection morphogenesis	ADCY10 ARHGAP32 NEDD4L NCKAP1 MYCBP2 DBNL SPAG9 APP EDN2 MAPK8IP3 NEDD4 DST PLXNA4 DIAPH2 MACF1 AFDN NOTCH2 MOV10	1.11e-04	819	166	18	GO:0120039
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	ADCY10 ARHGAP32 NEDD4L MYCBP2 DBNL APP EDN2 MAPK8IP3 NEDD4 DST PLXNA4 DIAPH2 MACF1 AFDN ATP2B2 NOTCH2 TBCD	1.16e-04	748	166	17	GO:0048667
GeneOntologyBiologicalProcess	cell projection morphogenesis	ADCY10 ARHGAP32 NEDD4L NCKAP1 MYCBP2 DBNL SPAG9 APP EDN2 MAPK8IP3 NEDD4 DST PLXNA4 DIAPH2 MACF1 AFDN NOTCH2 MOV10	1.23e-04	826	166	18	GO:0048858
GeneOntologyBiologicalProcess	developmental growth involved in morphogenesis	ADCY10 ARHGAP32 NEDD4L DBNL SPAG9 APP EDN2 PLXNA4 MACF1 AFDN	1.60e-04	299	166	10	GO:0060560
GeneOntologyBiologicalProcess	developmental cell growth	ADCY10 ARHGAP32 NEDD4L DBNL SPAG9 APP EDN2 PLXNA4 MACF1 AFDN	1.69e-04	301	166	10	GO:0048588
GeneOntologyBiologicalProcess	microtubule bundle formation	CFAP91 SPEF2 MAP7 DNAH7 FSIP2 TEKT2 DNAAF1	1.75e-04	145	166	7	GO:0001578
GeneOntologyCellularComponent	heterochromatin	EME1 CENPB KDM4C NOP53 BMI1 KDM4A UHRF2	1.88e-05	101	170	7	GO:0000792
GeneOntologyCellularComponent	axon	GABRD ADCY10 ZC3H14 ANK1 HTR3A MYCBP2 TSPOAP1 KIF21A EXOC3 MAP7 APP BCR MAPK8IP3 DST MAP1LC3B2 GLRA1 PPP1R2P1 DLG2 AFDN MAP1LC3B	3.93e-05	891	170	20	GO:0030424
GeneOntologyCellularComponent	cytoplasmic region	ZC3H14 CFAP91 PPFIA3 DNAH7 MAPK8IP3 TEKT2 DST MAP1LC3B2 DLG2 MAP1LC3B DNAAF1 NLRP5	4.06e-05	360	170	12	GO:0099568
GeneOntologyCellularComponent	pericentric heterochromatin	CENPB KDM4C KDM4A UHRF2	1.27e-04	32	170	4	GO:0005721
GeneOntologyCellularComponent	plasma membrane bounded cell projection cytoplasm	ZC3H14 CFAP91 DNAH7 MAPK8IP3 TEKT2 DST MAP1LC3B2 DLG2 MAP1LC3B DNAAF1	2.79e-04	317	170	10	GO:0032838
GeneOntologyCellularComponent	smooth endoplasmic reticulum	APP RYR3 MAPK8IP3 ITPR1	5.28e-04	46	170	4	GO:0005790
GeneOntologyCellularComponent	dendrite	GABRD ADCY10 ZC3H14 ARHGAP32 KIF21A DBNL APP BCR MAPK8IP3 ITPR1 NEDD4 MAP1LC3B2 GLRA1 PPP1R2P1 DLG2 MAP1LC3B ATP2B2	6.48e-04	858	170	17	GO:0030425
GeneOntologyCellularComponent	dendritic tree	GABRD ADCY10 ZC3H14 ARHGAP32 KIF21A DBNL APP BCR MAPK8IP3 ITPR1 NEDD4 MAP1LC3B2 GLRA1 PPP1R2P1 DLG2 MAP1LC3B ATP2B2	6.65e-04	860	170	17	GO:0097447
GeneOntologyCellularComponent	motile cilium	ADCY10 CFAP91 SPEF2 HVCN1 DNAH7 DNAH14 FSIP2 TEKT2 DAAM1 ATP2B4	6.77e-04	355	170	10	GO:0031514
GeneOntologyCellularComponent	cilium	ADCY10 CFAP91 SPEF2 EVC APP HVCN1 DNAH7 DNAH14 FSIP2 TEKT2 MAP1LC3B2 DAAM1 MAP1LC3B DNAAF1 ATP2B2 ATP2B4 NOTCH2	1.07e-03	898	170	17	GO:0005929
GeneOntologyCellularComponent	basal part of cell	ADCY10 ANK1 MAP7 ITGA9 DST TJP1 MTTP DLG2 ATP2B2 ATP2B4	1.09e-03	378	170	10	GO:0045178
Domain	PHD	KDM4C DIDO1 CHD3 CHD4 FBXL19 PHF14 KDM4A UHRF2	1.26e-06	89	166	8	SM00249
Domain	Znf_PHD	KDM4C DIDO1 CHD3 CHD4 FBXL19 PHF14 KDM4A UHRF2	1.49e-06	91	166	8	IPR001965
Domain	ZF_PHD_2	KDM4C DIDO1 CHD3 CHD4 FBXL19 PHF14 KDM4A UHRF2	2.07e-06	95	166	8	PS50016
Domain	ZF_PHD_1	KDM4C DIDO1 CHD3 CHD4 FBXL19 PHF14 KDM4A UHRF2	2.25e-06	96	166	8	PS01359
Domain	Znf_FYVE_PHD	KDM4C DIDO1 CHD3 CHD4 FBXL19 PHF14 KDM4A UHRF2	5.14e-05	147	166	8	IPR011011
Domain	Chromo_domain	CHD9 CHD2 CHD3 CHD4	5.57e-05	24	166	4	IPR023780
Domain	Znf_PHD-finger	DIDO1 CHD3 CHD4 FBXL19 PHF14 UHRF2	7.32e-05	79	166	6	IPR019787
Domain	Chromo	CHD9 CHD2 CHD3 CHD4	7.72e-05	26	166	4	PF00385
Domain	JIP_LZII	SPAG9 MAPK8IP3	7.85e-05	2	166	2	IPR032486
Domain	JIP_LZII	SPAG9 MAPK8IP3	7.85e-05	2	166	2	PF16471
Domain	CHROMO_1	CHD9 CHD2 CHD3 CHD4	1.04e-04	28	166	4	PS00598
Domain	CHROMO_2	CHD9 CHD2 CHD3 CHD4	1.04e-04	28	166	4	PS50013
Domain	SNF2_N	CHD9 CHD2 CHD3 CHD4	1.78e-04	32	166	4	IPR000330
Domain	SNF2_N	CHD9 CHD2 CHD3 CHD4	1.78e-04	32	166	4	PF00176
Domain	Chromodomain-like	CHD9 CHD2 CHD3 CHD4	1.78e-04	32	166	4	IPR016197
Domain	P-loop_NTPase	ADCY10 GTPBP4 DDX59 SPEF2 KIF21A NVL CHD9 CHD2 CHD3 CHD4 HNRNPUL1 DNAH7 DNAH14 TJP1 DLG2 DSEL HS3ST2 MOV10 NLRP5	1.98e-04	848	166	19	IPR027417
Domain	Chromo/shadow_dom	CHD9 CHD2 CHD3 CHD4	2.01e-04	33	166	4	IPR000953
Domain	CHROMO	CHD9 CHD2 CHD3 CHD4	2.01e-04	33	166	4	SM00298
Domain	CHD_N	CHD3 CHD4	2.34e-04	3	166	2	IPR012958
Domain	CHD_C2	CHD3 CHD4	2.34e-04	3	166	2	IPR012957
Domain	CHDCT2	CHD3 CHD4	2.34e-04	3	166	2	PF08074
Domain	CHDNT	CHD3 CHD4	2.34e-04	3	166	2	PF08073
Domain	DUF1086	CHD3 CHD4	2.34e-04	3	166	2	IPR009462
Domain	DUF1087	CHD3 CHD4	2.34e-04	3	166	2	IPR009463
Domain	DUF1087	CHD3 CHD4	2.34e-04	3	166	2	PF06465
Domain	DUF1086	CHD3 CHD4	2.34e-04	3	166	2	PF06461
Domain	DUF1087	CHD3 CHD4	2.34e-04	3	166	2	SM01147
Domain	DUF1086	CHD3 CHD4	2.34e-04	3	166	2	SM01146
Domain	Zinc_finger_PHD-type_CS	DIDO1 CHD3 CHD4 FBXL19 PHF14	2.80e-04	65	166	5	IPR019786
Domain	-	ADCY10 GTPBP4 DDX59 SPEF2 NVL CHD9 CHD2 CHD3 CHD4 HNRNPUL1 DNAH7 DNAH14 TJP1 DLG2 DSEL HS3ST2 MOV10	3.59e-04	746	166	17	3.40.50.300
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B4	4.66e-04	4	166	2	IPR022141
Domain	JNK/Rab-associated_protein-1_N	SPAG9 MAPK8IP3	4.66e-04	4	166	2	IPR019143
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B4	4.66e-04	4	166	2	PF12424
Domain	Jnk-SapK_ap_N	SPAG9 MAPK8IP3	4.66e-04	4	166	2	PF09744
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B4	4.66e-04	4	166	2	IPR006408
Domain	PHD	DIDO1 CHD3 CHD4 PHF14 UHRF2	5.46e-04	75	166	5	PF00628
Domain	RH2	SPAG9 MAPK8IP3	7.72e-04	5	166	2	PS51777
Domain	RH1	SPAG9 MAPK8IP3	7.72e-04	5	166	2	PS51776
Domain	EPHD	KDM4C PHF14 KDM4A	9.38e-04	22	166	3	PS51805
Domain	Rho_GTPase_activation_prot	STARD13 ARHGAP32 BCR PLXNA4 ARHGAP21	1.13e-03	88	166	5	IPR008936
Domain	RIH_assoc-dom	RYR3 ITPR1	1.15e-03	6	166	2	IPR013662
Domain	-	DST MACF1	1.15e-03	6	166	2	3.90.1290.10
Domain	GAR	DST MACF1	1.15e-03	6	166	2	PS51460
Domain	Ins145_P3_rec	RYR3 ITPR1	1.15e-03	6	166	2	PF08709
Domain	GAS2	DST MACF1	1.15e-03	6	166	2	PF02187
Domain	RIH_assoc	RYR3 ITPR1	1.15e-03	6	166	2	PF08454
Domain	RIH_dom	RYR3 ITPR1	1.15e-03	6	166	2	IPR000699
Domain	Ins145_P3_rcpt	RYR3 ITPR1	1.15e-03	6	166	2	IPR014821
Domain	Ryanodine_recept-rel	RYR3 ITPR1	1.15e-03	6	166	2	IPR015925
Domain	-	RYR3 ITPR1	1.15e-03	6	166	2	1.25.10.30
Domain	-	DST MACF1	1.15e-03	6	166	2	3.30.920.20
Domain	RYDR_ITPR	RYR3 ITPR1	1.15e-03	6	166	2	PF01365
Domain	GAS_dom	DST MACF1	1.15e-03	6	166	2	IPR003108
Domain	GAS2	DST MACF1	1.15e-03	6	166	2	SM00243
Domain	Plectin	DST MACF1	1.60e-03	7	166	2	PF00681
Domain	Plectin_repeat	DST MACF1	1.60e-03	7	166	2	IPR001101
Domain	PLEC	DST MACF1	1.60e-03	7	166	2	SM00250
Domain	PDZ	ARHGEF11 MAST2 TJP1 DLG2 AFDN ARHGAP21	1.64e-03	141	166	6	PF00595
Domain	HECT	NEDD4L NEDD4 UBR5	1.72e-03	27	166	3	PF00632
Domain	HECTc	NEDD4L NEDD4 UBR5	1.72e-03	27	166	3	SM00119
Domain	HECT_dom	NEDD4L NEDD4 UBR5	1.72e-03	27	166	3	IPR000569
Domain	HECT	NEDD4L NEDD4 UBR5	1.72e-03	27	166	3	PS50237
Domain	-	NEDD4L BCR NEDD4 PIK3CB FER1L5 PLCE1	2.10e-03	148	166	6	2.60.40.150
Domain	PDZ	ARHGEF11 MAST2 TJP1 DLG2 AFDN ARHGAP21	2.10e-03	148	166	6	SM00228
Domain	DAD_dom	DIAPH2 DAAM1	2.12e-03	8	166	2	IPR014767
Domain	DAD	DIAPH2 DAAM1	2.12e-03	8	166	2	PS51231
Domain	E2F	E2F7 E2F6	2.12e-03	8	166	2	IPR015633
Domain	Atg8	MAP1LC3B2 MAP1LC3B	2.12e-03	8	166	2	PF02991
Domain	Atg8-like	MAP1LC3B2 MAP1LC3B	2.12e-03	8	166	2	IPR004241
Domain	-	ARHGEF11 MAST2 TJP1 DLG2 AFDN ARHGAP21	2.25e-03	150	166	6	2.30.42.10
Domain	RhoGAP	STARD13 ARHGAP32 BCR ARHGAP21	2.25e-03	62	166	4	SM00324
Domain	PDZ	ARHGEF11 MAST2 TJP1 DLG2 AFDN ARHGAP21	2.32e-03	151	166	6	PS50106
Domain	RhoGAP	STARD13 ARHGAP32 BCR ARHGAP21	2.38e-03	63	166	4	PF00620
Domain	PDZ	ARHGEF11 MAST2 TJP1 DLG2 AFDN ARHGAP21	2.40e-03	152	166	6	IPR001478
Domain	RhoGAP_dom	STARD13 ARHGAP32 BCR ARHGAP21	2.53e-03	64	166	4	IPR000198
Domain	RHOGAP	STARD13 ARHGAP32 BCR ARHGAP21	2.53e-03	64	166	4	PS50238
Domain	-	STARD13 ARHGAP32 BCR ARHGAP21	2.53e-03	64	166	4	1.10.555.10
Domain	Helicase_C	DDX59 CHD9 CHD2 CHD3 CHD4	2.68e-03	107	166	5	PF00271
Domain	HELICc	DDX59 CHD9 CHD2 CHD3 CHD4	2.68e-03	107	166	5	SM00490
Domain	Drf_GBD	DIAPH2 DAAM1	2.71e-03	9	166	2	PF06371
Domain	Drf_FH3	DIAPH2 DAAM1	2.71e-03	9	166	2	PF06367
Domain	ZU5	ANK1 TJP1	2.71e-03	9	166	2	SM00218
Domain	FH3_dom	DIAPH2 DAAM1	2.71e-03	9	166	2	IPR010472
Domain	GTPase-bd	DIAPH2 DAAM1	2.71e-03	9	166	2	IPR010473
Domain	Drf_FH3	DIAPH2 DAAM1	2.71e-03	9	166	2	SM01139
Domain	Drf_GBD	DIAPH2 DAAM1	2.71e-03	9	166	2	SM01140
Domain	Helicase_C	DDX59 CHD9 CHD2 CHD3 CHD4	2.79e-03	108	166	5	IPR001650
Domain	JMJC	KDM4C RIOX1 KDM4A	2.83e-03	32	166	3	PS51184
Domain	JmjC_dom	KDM4C RIOX1 KDM4A	2.83e-03	32	166	3	IPR003347
Domain	HELICASE_CTER	DDX59 CHD9 CHD2 CHD3 CHD4	2.90e-03	109	166	5	PS51194
Domain	HELICASE_ATP_BIND_1	DDX59 CHD9 CHD2 CHD3 CHD4	2.90e-03	109	166	5	PS51192
Domain	DEXDc	DDX59 CHD9 CHD2 CHD3 CHD4	2.90e-03	109	166	5	SM00487
Domain	-	KIF21A GEMIN5 SPAG9 EDC4 PPWD1 DCAF5 BRWD3 MAPK8IP3 PLXNA4	3.00e-03	333	166	9	2.130.10.10
Domain	Helicase_ATP-bd	DDX59 CHD9 CHD2 CHD3 CHD4	3.02e-03	110	166	5	IPR014001
Domain	JmjC	KDM4C RIOX1 KDM4A	3.09e-03	33	166	3	SM00558
Domain	WD40/YVTN_repeat-like_dom	KIF21A GEMIN5 SPAG9 EDC4 PPWD1 DCAF5 BRWD3 MAPK8IP3 PLXNA4	3.12e-03	335	166	9	IPR015943
Domain	SH3	ARHGAP32 TSPOAP1 DBNL DST TJP1 MACF1 DLG2	3.23e-03	216	166	7	PS50002
Domain	MIR	RYR3 ITPR1	3.37e-03	10	166	2	PF02815
Domain	JmjN	KDM4C KDM4A	3.37e-03	10	166	2	SM00545
Domain	MIR_motif	RYR3 ITPR1	3.37e-03	10	166	2	IPR016093
Pathway	REACTOME_RHOB_GTPASE_CYCLE	STARD13 ARHGAP32 ARHGEF11 BCR STK10 DAAM1 ARHGAP21	2.92e-06	69	128	7	MM15596
Pathway	REACTOME_RHOB_GTPASE_CYCLE	STARD13 ARHGAP32 ARHGEF11 BCR STK10 DAAM1 ARHGAP21	3.22e-06	70	128	7	M41806
Pathway	REACTOME_RHOC_GTPASE_CYCLE	STARD13 ARHGAP32 ARHGEF11 BCR STK10 DAAM1 ARHGAP21	3.22e-06	70	128	7	MM15597
Pathway	REACTOME_RHOC_GTPASE_CYCLE	STARD13 ARHGAP32 ARHGEF11 BCR STK10 DAAM1 ARHGAP21	4.69e-06	74	128	7	M41807
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RALGAPA1 TET2 CDK18 ARHGAP32 NEDD4L NCKAP1 MYCBP2 DBNL C19orf47 HNRNPUL1 EDC4 MAP7 MAST2 BCR DNAH7 DENND4C NEDD4 CDCA2 FSIP2 DST TJP1 MACF1 AFDN ARHGAP21 CEP170B NOTCH2	1.15e-13	861	169	26	36931259
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	GTPBP4 ZC3H14 NCKAP1 MYCBP2 NOP53 NVL GEMIN5 DIDO1 CHD2 SPAG9 CHD4 HNRNPUL1 EDC4 ESF1 GMPS DST UBR5 TJP1 MCM3AP MACF1 PYGL AFDN MOV10	1.45e-13	653	169	23	22586326
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	GTPBP4 ARHGAP32 NEDD4L NCKAP1 MYCBP2 KIF21A DIDO1 CHD4 EDC4 PPFIA3 ARHGEF11 BCR ARPC4 MAPK8IP3 NEDD4 DST UBR5 TJP1 DIAPH2 MACF1 DLG2 AFDN ATP2B4 ARHGAP21 CEP170B	9.50e-12	963	169	25	28671696
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	GTPBP4 ZC3H14 TICRR CENPB MYCBP2 NOP53 C19orf47 NVL DIDO1 CHD3 CHD4 HNRNPUL1 SARNP MTPAP ESF1 CDCA2 RSBN1 MRM3 CKAP2L MACF1 TOP2A MOV10	2.30e-11	759	169	22	35915203
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	STARD13 CDK18 CFAP91 CENPB NCKAP1 MYCBP2 EXOC3 SPAG9 HNRNPUL1 FBXL19 MAP7 SARNP BCR ARPC4 MTPAP DENND4C ESF1 FANCB TEKT2 NDUFAF4 PYGL AFDN DNAAF1 VPS51 ATP2B2 SOAT1 MOV10 TBCD	5.48e-11	1321	169	28	27173435
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	GABRD TET2 CFAP91 ZCCHC12 MYCBP2 KDM4C KIF21A CHD9 CHD4 QRICH1 HNRNPUL1 APP USP9Y DCAF5 BRWD3 RYR3 MAPK8IP3 DST ZNF532 TJP1 SGSM2 SENP6 MACF1 DLG2 AFDN KDM4A ARHGAP21	1.53e-10	1285	169	27	35914814
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	RALGAPA1 CDC42BPG NEDD4L MYCBP2 EVC CHD9 CHD2 CHD3 ATP8B1 APP BCR TSEN2 BRWD3 DNAH14 MAPK8IP3 GMPS STK10 ZNF532 TJP1 SGSM2 USP40 MACF1 PLA2G6 PHF14 DAAM1 SPIDR CEP170B NOTCH2 TBCD	1.74e-10	1489	169	29	28611215
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	GTPBP4 DDX59 NEDD4L CENPB NCKAP1 MYCBP2 NOP53 KIF21A DBNL GEMIN5 DIDO1 HNRNPUL1 NDUFA6 MAP7 APP SARNP MTPAP GMPS NDUFAF4 DST UBR5 TJP1 SMARCB1 MACF1 MAP1LC3B NOTCH2 SOAT1	1.88e-10	1297	169	27	33545068
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	GTPBP4 ZC3H14 CENPB NVL GEMIN5 DIDO1 CHD9 CHD2 CHD3 CHD4 QRICH1 SARNP PPWD1 ESF1 GMPS CACTIN ZNF532 UBR5 SMARCB1 PYGL PHF14 UHRF2 TOP2A	9.49e-10	1014	169	23	32416067
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	GTPBP4 CENPB CHD9 ECT2L CHD3 CHD4 PPFIA3 MAP7 APP MAST2 BCR MTPAP DCAF5 BRWD3 RSBN1 CACTIN UBR5 MCM3AP SMARCB1 MACF1 VPS51 TOP2A CEP170B NOTCH2	1.13e-09	1116	169	24	31753913
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	RALGAPA1 ARHGAP32 NEDD4L NCKAP1 DBNL GEMIN5 CHD3 EDC4 NDUFA6 PPFIA3 MAP7 ARHGEF11 BCR ARPC4 MAPK8IP3 TENM4 DST TJP1 PLXNA4 MACF1 DLG2 AFDN VPS51 ATP2B2 ATP2B4 ARHGAP21 CEP170B	1.59e-09	1431	169	27	37142655
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	NEDD4L NCKAP1 TSPOAP1 R3HDM2 DCAF5 NEDD4 RSBN1 TENM4 UBR5 SGSM2 MCM3AP MACF1 ARHGAP21 CEP170B PLCE1	1.68e-09	407	169	15	12693553
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	GTPBP4 DDX59 MYCBP2 NVL GEMIN5 CHD4 HNRNPUL1 SARNP ESF1 ITPR1 PCF11 CDCA2 UBR5 TOP2A MOV10	4.82e-09	440	169	15	34244565
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	GTPBP4 NVL DIDO1 CHD9 CHD2 CHD3 CHD4 CDCA2 FSIP2 BMI1 CACTIN SMARCB1 SENP6 PHF14 KDM4A UHRF2 TOP2A	8.37e-09	608	169	17	36089195
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ARHGAP32 NEDD4L NCKAP1 MYCBP2 TSPOAP1 DBNL EDC4 NDUFA6 PPFIA3 APP BCR MAPK8IP3 ITPR1 GMPS TENM4 TJP1 PPP1R2P1 MACF1 DLG2 AFDN DAAM1 VPS51 CEP170B	8.45e-09	1139	169	23	36417873
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	EME1 ERCC5 MYCBP2 GEMIN5 DIDO1 CHD3 SPAG9 CHD4 HNRNPUL1 ESF1 MAPK8IP3 PCF11 STK10 CACTIN SENP6 AFDN PHF14 TOP2A NOTCH2	8.70e-09	774	169	19	15302935
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	STARD13 EME1 ERCC5 SPEF2 KIF21A DBNL CHD2 CHD3 CHD4 ARPC4 ESF1 PCF11 CDCA2 DST TJP1 VASH2 PLXNA4 MTTP MACF1 DLG2 PHF14 BTNL9 ATP2B2 ARHGAP21 TOP2A	3.60e-08	1442	169	25	35575683
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 NEDD4L MYCBP2 CHD3 QRICH1 HNRNPUL1 NEDD4 DST UBR5 MCM3AP MACF1 AFDN DAAM1 UHRF2 NOTCH2 TBCD	3.67e-08	591	169	16	15231748
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	STARD13 GTPBP4 NCKAP1 MYCBP2 KIF21A DBNL EXOC3 GEMIN5 CHD2 CHD4 HNRNPUL1 ARPC4 MTPAP ESF1 GMPS CDCA2 DST UBR5 MCM3AP MACF1 PYGL AFDN TOP2A MOV10	4.55e-08	1353	169	24	29467282
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	ZC3H14 NCKAP1 NOP53 DBNL GEMIN5 DIDO1 ECT2L CHD2 EDC4 MAP7 APP ARHGEF11 ZBTB7B MTPAP ESF1 PCF11 RSBN1 MRM3 DST MACF1 AFDN PHF14 DAAM1 CEP170B MOV10	7.37e-08	1497	169	25	31527615
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ANKRD13D MYCBP2 C19orf47 GEMIN5 EDC4 FBXL19 ARHGEF11 MAST2 BCR MAPK8IP3 STK10 DST SGSM2 MCM3AP USP40 DIAPH2 PLA2G6 ARHGAP21 CEP170B NOTCH2 TBCD	1.10e-07	1105	169	21	35748872
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	ANK1 NCKAP1 EXOC3 CHD9 CHD2 USP9Y ARHGEF11 SPATA31A6 RYR3 NDUFAF4 DIAPH2 SMARCB1 KDM4A ARHGAP21	1.68e-07	497	169	14	36774506
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	NEDD4L KIF21A DBNL EDC4 ARPC4 GMPS DST TJP1 SMARCB1 MACF1 PYGL ARHGAP21 TOP2A TBCD	1.72e-07	498	169	14	36634849
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TET2 ARHGAP32 ARHGEF11 MAST2 TSEN2 DST MCM3AP MACF1	2.58e-07	130	169	8	12421765
Pubmed	Multidimensional Proteomics Reveals a Role of UHRF2 in the Regulation of Epithelial-Mesenchymal Transition (EMT).	DIDO1 CHD2 CHD3 GMPS BMI1 UHRF2	2.87e-07	55	169	6	27114453
Pubmed	Characterization of the CHD family of proteins.	CHD2 CHD3 CHD4	4.49e-07	4	169	3	9326634
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	TET2 ZC3H14 MYCBP2 DIDO1 CHD9 CHD3 CHD4 QRICH1 HNRNPUL1 EDC4 SARNP PPWD1 GMPS PCF11 STK10 UBR5 SMARCB1 PYGL UHRF2 TOP2A	4.72e-07	1103	169	20	34189442
Pubmed	Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	ARHGAP32 KDM4C MAST2 DST SENP6 MACF1 PHF14	6.62e-07	101	169	7	9872452
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	CDC42BPG TICRR ANK1 KIF21A CHD2 SPAG9 PPFIA3 MTPAP DNAH14 GMPS NDUFAF4 DST MCM3AP PLXNA4 PHF14 PWWP3B	6.97e-07	736	169	16	29676528
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	GTPBP4 ZC3H14 DBNL GEMIN5 DIDO1 CHD3 SPAG9 CHD4 HNRNPUL1 EDC4 ESF1 GMPS DST TJP1 SENP6 MACF1 ARHGAP21 TOP2A	7.76e-07	934	169	18	33916271
Pubmed	Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3 ubiquitin ligases.	NEDD4L NEDD4 TJP1 DLG2	9.36e-07	16	169	4	21920314
Pubmed	Interactomes of Glycogen Synthase Kinase-3 Isoforms.	EDC4 MAP7 BCR DENND4C DST UBR5 MACF1 ARHGAP21 CEP170B	9.36e-07	209	169	9	36779422
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 GTPBP4 CDK18 MYCBP2 NVL EXOC3 E2F6 HNRNPUL1 NDUFA6 MAP7 APP DCAF5 ESF1 ITPR1 PCF11 CACTIN NDUFAF4 UBR5 MACF1 DAAM1 ATP2B4 NOTCH2 SOAT1	9.73e-07	1487	169	23	33957083
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 MYCBP2 GEMIN5 CHD3 CHD4 E2F6 BCR DENND4C DST ZNF532 UBR5 ARHGAP21	1.08e-06	418	169	12	34709266
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ARHGAP32 NEDD4L CCDC28A EXOC3 APP STK10 DST MACF1 DAAM1 ATP2B4 ARHGAP21 NOTCH2	1.17e-06	421	169	12	36976175
Pubmed	Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.	RALGAPA1 CDK18 ARHGAP32 NCKAP1 DBNL PPFIA3 ARPC4 UBR5 MACF1 DLG2 ARHGAP21 CEP170B	1.45e-06	430	169	12	32581705
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RALGAPA1 CDK18 NCKAP1 R3HDM2 MAST2 DENND4C DST UBR5 TJP1 AFDN CEP170B NOTCH2	2.12e-06	446	169	12	24255178
Pubmed	Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.	DLG2 ATP2B2 ATP2B4	2.23e-06	6	169	3	11274188
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TET2 NEDD4L QRICH1 MAP7 ITPR1 NEDD4 MELTF TENM4 DIAPH2 KDM4A DAAM1 FTO NOTCH2	2.47e-06	536	169	13	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TET2 NEDD4L QRICH1 MAP7 ITPR1 NEDD4 MELTF TENM4 DIAPH2 KDM4A DAAM1 FTO NOTCH2	2.57e-06	538	169	13	10512203
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GTPBP4 ZC3H14 NEDD4L MYCBP2 C19orf47 EXOC3 CHD3 CHD4 HNRNPUL1 EDC4 APP DST UBR5 TJP1 CKAP2L MACF1 AFDN TOP2A	2.83e-06	1024	169	18	24711643
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	RALGAPA1 ZC3H14 DDX59 DBNL E2F7 DIDO1 CHD9 SPAG9 CHD4 MAP7 APP DNAH14 NEDD4 RSBN1 PIK3CB LTB4R SPIDR	3.02e-06	925	169	17	28986522
Pubmed	FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.	NOP53 RIOX1 CHD3 CHD4 HNRNPUL1 DNAH7 ESF1 GMPS TOP2A	3.82e-06	248	169	9	27926873
Pubmed	Induced Mist1 expression promotes remodeling of mouse pancreatic acinar cells.	MAP1LC3B2 TJP1 MAP1LC3B	3.89e-06	7	169	3	22510200
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	EXOC3 DIDO1 CHD9 CHD2 CHD3 HNRNPUL1 EDC4 TJP1 SMARCB1 PHF14 TOP2A	4.01e-06	394	169	11	27248496
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	ZC3H14 NOP53 NVL DIDO1 CHD3 CHD4 HNRNPUL1 SARNP ESF1 PCF11 CDCA2 RSBN1 TJP1 SENP6 AFDN PHF14 TOP2A	4.54e-06	954	169	17	36373674
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	GTPBP4 NVL HNRNPUL1 ARHGEF11 SARNP PPWD1 ARPC4 MRM3 MELTF DST TJP1 CSNK1G1 MACF1 TOP2A	4.72e-06	660	169	14	32780723
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	GTPBP4 ZC3H14 CENPB NVL EDC4 ESF1 TJP1 MCM3AP PHF14 TOP2A	5.74e-06	332	169	10	25693804
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	GTPBP4 ZC3H14 TICRR NOP53 NVL DIDO1 RIOX1 CHD3 QRICH1 DST MOV10	5.84e-06	410	169	11	26949251
Pubmed	Human transcription factor protein interaction networks.	TET2 GTPBP4 ARHGAP32 NOP53 DIDO1 R3HDM2 PROSER1 CHD3 SPAG9 E2F6 HNRNPUL1 EDC4 MAP7 ARPC4 DCAF5 PCF11 CDCA2 RSBN1 DST SMARCB1 MOV10	6.60e-06	1429	169	21	35140242
Pubmed	MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.	GTPBP4 NOP53 C19orf47 NVL DIDO1 CHD4 E2F6 CDCA2 CACTIN SENP6	6.89e-06	339	169	10	30415952
Pubmed	Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.	GTPBP4 CDC42BPG NEDD4L NOP53 EDC4 MTPAP PYGL DAAM1 MOV10	1.11e-05	283	169	9	21903422
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	GTPBP4 MYCBP2 NOP53 GEMIN5 DIDO1 MAP7 MAST2 ARPC4 PCF11 MACF1	1.19e-05	361	169	10	26167880
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	GTPBP4 NEDD4L DIDO1 RIOX1 CHD2 CHD3 CHD4 MTPAP PCF11 PRKD3 RSBN1 MRM3 CACTIN TJP1 CSNK1G1 MCM3AP SMARCB1 CKAP2L ATP2B4 MOV10	1.24e-05	1371	169	20	36244648
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	KDM4C CHD2 CHD3 CHD4 BMI1 SMARCB1 KDM4A	1.25e-05	157	169	7	30186101
Pubmed	Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains.	GTPBP4 NOP53 NVL CHD9 CHD2 CHD3 CHD4 E2F6 SARNP BMI1 SMARCB1 TOP2A	1.28e-05	533	169	12	30554943
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	NCKAP1 MYCBP2 DBNL GEMIN5 SPAG9 CHD4 HNRNPUL1 MAP7 SARNP ESF1 GMPS DST UBR5 MACF1 PYGL AFDN MAP1LC3B MOV10	1.36e-05	1149	169	18	35446349
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	RALGAPA1 ZC3H14 CHD3 SARNP PPWD1 ARPC4 DST UBR5 MACF1 ATP2B2 TOP2A MOV10	1.40e-05	538	169	12	28524877
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPA1 ARHGAP32 MYCBP2 NOP53 EXOC3 SPAG9 PPFIA3 APP ESF1 ITPR1 GMPS PCF11 CDCA2 CACTIN TJP1 FTO ATP2B4	1.55e-05	1049	169	17	27880917
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	GTPBP4 NVL CHD9 R3HDM2 UBR5 UHRF2	1.61e-05	109	169	6	33554859
Pubmed	Large-scale phosphomimetic screening identifies phospho-modulated motif-based protein interactions.	GTPBP4 ZC3H14 HNRNPUL1 NEDD4 CDCA2 MAP1LC3B	1.70e-05	110	169	6	37219487
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	GTPBP4 ZC3H14 TICRR EME1 DIDO1 CHD2 CHD3 CHD4 E2F6 HNRNPUL1 MAP7 ZBTB7B CDCA2 CACTIN DST SMARCB1 PHF14 TOP2A SOAT1	1.90e-05	1294	169	19	30804502
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	CDC42BPG EXOC3 DIDO1 CHD3 MAST2 BCR ESF1 ITPR1 DST DIAPH2 AFDN ARHGAP21 PLCE1	1.93e-05	650	169	13	38777146
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	TET2 GTPBP4 GEMIN5 RIOX1 CHD3 CHD4 HNRNPUL1 MTPAP DCAF5 RSBN1 UBR5 MCM3AP MOV10	2.09e-05	655	169	13	35819319
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	ARHGAP32 DBNL EXOC3 DENND4C DST TJP1 MACF1 AFDN DAAM1 ATP2B4 ARHGAP21 NOTCH2	2.27e-05	565	169	12	25468996
Pubmed	Molecular analysis of a major antigenic region of the 240-kD protein of Mi-2 autoantigen.	CHD3 CHD4	2.35e-05	2	169	2	7560064
Pubmed	Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	25421500
Pubmed	PI3-K- and PKC-dependent up-regulation of APP processing enzymes by retinoic acid.	APP PIK3CB	2.35e-05	2	169	2	17986385
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	2.35e-05	2	169	2	11002341
Pubmed	Autophagic protein LC3B confers resistance against hypoxia-induced pulmonary hypertension.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	20889906
Pubmed	A novel mouse Nedd4 protein suppresses the activity of the epithelial Na+ channel.	NEDD4L NEDD4	2.35e-05	2	169	2	11149908
Pubmed	Microtubule-associated protein 1B is involved in the initial stages of axonogenesis in peripheral nervous system cultured neurons.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	12088839
Pubmed	Lc3 over-expression improves survival and attenuates lung injury through increasing autophagosomal clearance in septic mice.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	22968077
Pubmed	The major dermatomyositis-specific Mi-2 autoantigen is a presumed helicase involved in transcriptional activation.	CHD3 CHD4	2.35e-05	2	169	2	7575689
Pubmed	Dietary sodium modulates nephropathy in Nedd4-2-deficient mice.	NEDD4L NEDD4	2.35e-05	2	169	2	31802037
Pubmed	Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.	SPAG9 MAPK8IP3	2.35e-05	2	169	2	33788575
Pubmed	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.	ATP2B2 ATP2B4	2.35e-05	2	169	2	1313367
Pubmed	Cross-talk between miR-471-5p and autophagy component proteins regulates LC3-associated phagocytosis (LAP) of apoptotic germ cells.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	28928467
Pubmed	ACAT1 regulates the dynamics of free cholesterols in plasma membrane which leads to the APP-α-processing alteration.	APP SOAT1	2.35e-05	2	169	2	26474739
Pubmed	Transcriptomic Changes Predict Metabolic Alterations in LC3 Associated Phagocytosis in Aged Mice.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	37047689
Pubmed	Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.	ATP2B2 ATP2B4	2.35e-05	2	169	2	22252018
Pubmed	Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.	ATP2B2 ATP2B4	2.35e-05	2	169	2	25690014
Pubmed	Physiological Functions of the Ubiquitin Ligases Nedd4-1 and Nedd4-2.	NEDD4L NEDD4	2.35e-05	2	169	2	37962894
Pubmed	Cell-Penetrating Nanoparticles Activate the Inflammasome to Enhance Antibody Production by Targeting Microtubule-Associated Protein 1-Light Chain 3 for Degradation.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	32057231
Pubmed	Amyloid beta peptide binds a novel death-inducing protein, AB-DIP.	QRICH1 APP	2.35e-05	2	169	2	15923395
Pubmed	Targeting DCAF5 suppresses SMARCB1-mutant cancer by stabilizing SWI/SNF.	DCAF5 SMARCB1	2.35e-05	2	169	2	38538798
Pubmed	Rho GTP exchange factor ARHGEF11 regulates the integrity of epithelial junctions by connecting ZO-1 and RhoA-myosin II signaling.	ARHGEF11 TJP1	2.35e-05	2	169	2	22665792
Pubmed	Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif.	SPAG9 MAPK8IP3	2.35e-05	2	169	2	31690808
Pubmed	Distinct characteristics of two human Nedd4 proteins with respect to epithelial Na(+) channel regulation.	NEDD4L NEDD4	2.35e-05	2	169	2	11502596
Pubmed	MiR-196a promotes the proliferation and migration of esophageal cancer via the UHRF2/TET2 axis.	TET2 UHRF2	2.35e-05	2	169	2	34826027
Pubmed	Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of MyD88.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	27265145
Pubmed	Nedd4 and Nedd4-2: ubiquitin ligases at work in the neuron.	NEDD4L NEDD4	2.35e-05	2	169	2	23262292
Pubmed	Down-regulating destruction: phosphorylation regulates the E3 ubiquitin ligase Nedd4-2.	NEDD4L NEDD4	2.35e-05	2	169	2	19602703
Pubmed	Individual Atg8 paralogs and a bacterial metabolite sequentially promote hierarchical CASM-xenophagy induction and transition.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	38656870
Pubmed	Loss of hepatic SMLR1 causes hepatosteatosis and protects against atherosclerosis due to decreased hepatic VLDL secretion.	SMLR1 MTTP	2.35e-05	2	169	2	36053190
Pubmed	The anti-aggregation effects of ondansetron on platelets involve IP3 signaling and MAP kinase pathway, but not 5-HT3-dependent pathway.	HTR3A ITPR1	2.35e-05	2	169	2	22818390
Pubmed	[Preparation of an autophagy-targeted antituberculosis DNA vaccine encoding LpqH fused with LC3].	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	24909277
Pubmed	Structural investigations of the nickel-induced inhibition of truncated constructs of the JMJD2 family of histone demethylases using X-ray absorption spectroscopy.	KDM4C KDM4A	2.35e-05	2	169	2	23692052
Pubmed	Microtubule-Associated Protein 1 Light Chain 3B, (LC3B) Is Necessary to Maintain Lipid-Mediated Homeostasis in the Retinal Pigment Epithelium.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	30349463
Pubmed	Susceptibility of microtubule-associated protein 1 light chain 3β (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.	MAP1LC3B2 MAP1LC3B	2.35e-05	2	169	2	31431059
Interaction	SIRT7 interactions	GTPBP4 ZC3H14 NCKAP1 MYCBP2 NOP53 NVL GEMIN5 DIDO1 CHD2 SPAG9 CHD4 HNRNPUL1 EDC4 APP DCAF5 ESF1 GMPS DST UBR5 TJP1 MCM3AP MACF1 PYGL AFDN TOP2A MOV10	5.21e-10	744	167	26	int:SIRT7
Interaction	YWHAH interactions	RALGAPA1 TET2 CDC42BPG CDK18 ZC3H14 TICRR ARHGAP32 FOXO6 NEDD4L NCKAP1 MYCBP2 DBNL C19orf47 R3HDM2 HNRNPUL1 EDC4 MAP7 MAST2 BCR DNAH7 DENND4C NEDD4 CDCA2 DST TJP1 VASH2 MACF1 AFDN ARHGAP21 CEP170B NOTCH2	1.88e-09	1102	167	31	int:YWHAH
Interaction	YWHAG interactions	RALGAPA1 TET2 GTPBP4 CDK18 TICRR ARHGAP32 FOXO6 NEDD4L NCKAP1 MYCBP2 DBNL C19orf47 R3HDM2 HNRNPUL1 EDC4 MAP7 APP MAST2 BCR DNAH7 DENND4C NEDD4 CDCA2 DST TJP1 VASH2 MACF1 AFDN LTB4R MAP1LC3B ARHGAP21 CEP170B NOTCH2	2.43e-09	1248	167	33	int:YWHAG
Interaction	YWHAQ interactions	RALGAPA1 TET2 CDK18 TICRR ARHGAP32 FOXO6 NEDD4L NCKAP1 MYCBP2 C19orf47 R3HDM2 SPAG9 HNRNPUL1 MAP7 APP MAST2 BCR DNAH7 DENND4C NEDD4 DST TJP1 PIK3CB VASH2 MACF1 AFDN ARHGAP21 CEP170B SOAT1 TBCD	1.05e-08	1118	167	30	int:YWHAQ
Interaction	EED interactions	GTPBP4 CDC42BPG NCKAP1 MYCBP2 NVL GEMIN5 DIDO1 RIOX1 CHD2 CHD3 CHD4 E2F6 HNRNPUL1 NDUFA6 PPWD1 ARPC4 NEDD4 GMPS BMI1 TJP1 MTTP MACF1 AFDN FTO MAP1LC3B VPS51 UHRF2 TOP2A CEP170B SOAT1 MOV10 TBCD	2.75e-07	1445	167	32	int:EED
Interaction	YWHAB interactions	RALGAPA1 TET2 CDK18 TICRR ARHGAP32 FOXO6 NEDD4L NCKAP1 MYCBP2 R3HDM2 HNRNPUL1 MAP7 APP MAST2 BCR PPWD1 DENND4C NEDD4 DST TJP1 VASH2 MACF1 AFDN ARHGAP21 CEP170B SOAT1	2.79e-07	1014	167	26	int:YWHAB
Interaction	MB interactions	ANK1 KIF21A CHD3 CHD4 APP	3.90e-07	19	167	5	int:MB
Interaction	YWHAZ interactions	RALGAPA1 TET2 CDC42BPG CDK18 TICRR ARHGAP32 NEDD4L NCKAP1 MYCBP2 R3HDM2 HNRNPUL1 PPFIA3 MAP7 APP MAST2 BCR DENND4C ITPR1 NEDD4 FSIP2 DST TJP1 SMARCB1 MACF1 AFDN ATP2B2 ARHGAP21 CEP170B SOAT1 MOV10	3.96e-07	1319	167	30	int:YWHAZ
Interaction	CENPA interactions	GTPBP4 ERCC5 CENPB NOP53 CHD3 E2F6 ESF1 CDCA2 BMI1 RSBN1 CACTIN DIAPH2 SENP6 PHF14 TOP2A	6.07e-07	377	167	15	int:CENPA
Interaction	TNIK interactions	GTPBP4 ARHGAP32 NEDD4L NCKAP1 MYCBP2 EDC4 BCR NEDD4 DST TJP1 MACF1 DLG2 ARHGAP21 CEP170B	3.69e-06	381	167	14	int:TNIK
Interaction	NUP43 interactions	EME1 ERCC5 NOP53 DBNL CHD9 CHD3 E2F6 CDCA2 FSIP2 RSBN1 CACTIN DST ZNF532 UBR5 MCM3AP MTTP SENP6 TOP2A	4.63e-06	625	167	18	int:NUP43
Interaction	HECTD1 interactions	GTPBP4 ZC3H14 TICRR CENPB MYCBP2 NOP53 C19orf47 NVL DIDO1 CHD3 CHD4 HNRNPUL1 SARNP MTPAP ESF1 CDCA2 RSBN1 MRM3 CKAP2L MACF1 MAP1LC3B TOP2A MOV10	6.84e-06	984	167	23	int:HECTD1
Interaction	GSK3A interactions	ZC3H14 KIF21A EDC4 MAP7 APP ARHGEF11 BCR DENND4C PRKD3 DST UBR5 MACF1 MAP1LC3B ARHGAP21 CEP170B	7.75e-06	464	167	15	int:GSK3A
Interaction	HSFY1 interactions	E2F7 CHD3 CHD4 QRICH1 SMARCB1	8.43e-06	34	167	5	int:HSFY1
Interaction	TMEM255A interactions	ANKRD13D NEDD4L APP NEDD4	9.95e-06	17	167	4	int:TMEM255A
Interaction	CHTOP interactions	CDK18 ZC3H14 CHD3 CHD4 APP SARNP BMI1 KDM4A SOAT1 MOV10	1.13e-05	212	167	10	int:CHTOP
Interaction	FBXO22 interactions	ANK1 NCKAP1 KDM4C EXOC3 CHD9 CHD2 USP9Y ARHGEF11 SPATA31A6 RYR3 NDUFAF4 DIAPH2 SMARCB1 KDM4A MAP1LC3B ARHGAP21	1.14e-05	540	167	16	int:FBXO22
Interaction	YWHAE interactions	RALGAPA1 TET2 CDK18 TICRR ARHGAP32 NEDD4L NCKAP1 MYCBP2 DBNL R3HDM2 HNRNPUL1 MAP7 MAST2 BCR DENND4C NEDD4 BMI1 DST MACF1 AFDN MAP1LC3B ATP2B4 ARHGAP21 TOP2A CEP170B SOAT1	1.41e-05	1256	167	26	int:YWHAE
Interaction	POLD3 interactions	CHD4 APP TSEN2 CACTIN MELTF UHRF2 TOP2A	1.74e-05	98	167	7	int:POLD3
Interaction	SIRT6 interactions	GTPBP4 DDX59 MYCBP2 NVL GEMIN5 CHD3 CHD4 QRICH1 HNRNPUL1 SARNP ESF1 ITPR1 PCF11 CDCA2 UBR5 TOP2A MOV10	1.92e-05	628	167	17	int:SIRT6
Interaction	H2BC8 interactions	EME1 DDX59 ERCC5 NVL DIDO1 CHD3 CHD4 E2F6 SARNP ESF1 CDCA2 CACTIN SENP6 PHF14 FTO TOP2A	2.50e-05	576	167	16	int:H2BC8
Interaction	IFI16 interactions	GTPBP4 ZC3H14 CENPB NOP53 NVL E2F7 CHD4 HNRNPUL1 EDC4 APP ESF1 BMI1 MRM3 TJP1 MCM3AP PHF14 TOP2A MOV10	2.78e-05	714	167	18	int:IFI16
Interaction	SNCA interactions	NEDD4L KIF21A DBNL EDC4 APP ARPC4 NEDD4 GMPS BMI1 DST TJP1 SMARCB1 MACF1 PYGL MAP1LC3B ARHGAP21 TOP2A TBCD	2.88e-05	716	167	18	int:SNCA
Interaction	KCTD13 interactions	RALGAPA1 ARHGAP32 NEDD4L NCKAP1 DBNL GEMIN5 CHD3 EDC4 NDUFA6 PPFIA3 MAP7 ARHGEF11 BCR ARPC4 MAPK8IP3 TENM4 DST TJP1 PLXNA4 MACF1 DLG2 AFDN VPS51 ATP2B2 ATP2B4 ARHGAP21 CEP170B	3.07e-05	1394	167	27	int:KCTD13
Interaction	GSK3B interactions	CENPB NCKAP1 CHD3 EDC4 MAP7 APP ARHGEF11 BCR DENND4C GMPS DST UBR5 TJP1 MACF1 PYGL VPS51 ARHGAP21 TOP2A CEP170B NOTCH2	3.51e-05	868	167	20	int:GSK3B
Interaction	FMR1 interactions	NCKAP1 MYCBP2 CHD3 CHD4 EDC4 MAP7 NEDD4 TJP1 DIAPH2 MACF1 DLG2 ARHGAP21 TOP2A CEP170B MOV10	4.16e-05	536	167	15	int:FMR1
Interaction	APEX1 interactions	RALGAPA1 GTPBP4 ZC3H14 DDX59 ERCC5 KDM4C NOP53 DBNL E2F7 DIDO1 CHD9 SPAG9 CHD4 HNRNPUL1 MAP7 APP DNAH14 NEDD4 CDCA2 RSBN1 CACTIN PIK3CB CKAP2L LTB4R SPIDR	4.89e-05	1271	167	25	int:APEX1
Interaction	H3-3A interactions	KDM4C NVL DIDO1 CHD9 CHD2 CHD3 SPAG9 CHD4 BRWD3 NEDD4 CDCA2 CACTIN SMARCB1 SENP6 PHF14 KDM4A UHRF2 TOP2A	5.17e-05	749	167	18	int:H3-3A
Interaction	RNF123 interactions	CDC42BPG TICRR ANK1 KIF21A CHD2 SPAG9 PPFIA3 APP MTPAP DNAH14 GMPS NDUFAF4 DST MCM3AP PLXNA4 PHF14 PWWP3B MAP1LC3B MOV10	5.52e-05	824	167	19	int:RNF123
Interaction	PBRM1 interactions	KDM4C GEMIN5 CHD3 CHD4 E2F6 APP SMARCB1 KDM4A UHRF2 TOP2A	6.04e-05	258	167	10	int:PBRM1
Interaction	MS4A10 interactions	ANKRD13D NEDD4L NEDD4	6.43e-05	10	167	3	int:MS4A10
Interaction	RCOR1 interactions	MYCBP2 GEMIN5 CHD3 SPAG9 CHD4 E2F6 BCR DENND4C DST UBR5 SMARCB1 VPS51 UHRF2 ARHGAP21	6.61e-05	494	167	14	int:RCOR1
Interaction	SHANK3 interactions	NEDD4L NCKAP1 KIF21A DBNL APP BCR MAPK8IP3 ITPR1 NEDD4 MRM3 MACF1 DLG2 ATP2B2 NOTCH2	6.90e-05	496	167	14	int:SHANK3
Interaction	RAC1 interactions	RALGAPA1 CDC42BPG ARHGAP32 NCKAP1 EXOC3 ARHGEF11 SARNP BCR DENND4C NEDD4 STK10 DST MCM3AP DIAPH2 MACF1 DAAM1 VPS51 ARHGAP21 TOP2A NOTCH2 SOAT1 TBCD	6.95e-05	1063	167	22	int:RAC1
Interaction	RHOB interactions	RALGAPA1 GTPBP4 ARHGAP32 NEDD4L CCDC28A EXOC3 ARHGEF11 BCR PRKD3 STK10 TJP1 DIAPH2 MACF1 AFDN DAAM1 VPS51 ATP2B4 ARHGAP21 NOTCH2	7.13e-05	840	167	19	int:RHOB
Interaction	EIF4A3 interactions	ZC3H14 C19orf47 CHD3 CHD4 HNRNPUL1 SARNP PPWD1 ESF1 PCF11 BMI1 CACTIN UBR5 SMARCB1 MAP1LC3B	7.36e-05	499	167	14	int:EIF4A3
Interaction	TWIST1 interactions	GTPBP4 NVL CHD9 R3HDM2 CHD3 CHD4 UBR5 UHRF2	8.83e-05	170	167	8	int:TWIST1
Interaction	CBX3 interactions	CHD9 CHD3 CHD4 E2F6 ZBTB7B PPWD1 ESF1 CDCA2 BMI1 RSBN1 CACTIN DIAPH2 SENP6 MACF1 UHRF2 TOP2A	9.73e-05	646	167	16	int:CBX3
Interaction	DLG3 interactions	RALGAPA1 NEDD4L EXOC3 NEDD4 DLG2 ATP2B2 ATP2B4	1.12e-04	131	167	7	int:DLG3
Interaction	UNC79 interactions	MYCBP2 SPEF2 ZBTB7B	1.16e-04	12	167	3	int:UNC79
Interaction	BMI1 interactions	GEMIN5 DIDO1 CHD3 CHD4 E2F6 HNRNPUL1 EDC4 PPWD1 RYR3 BMI1 DST UBR5 UHRF2 TOP2A CEP170B MOV10	1.22e-04	659	167	16	int:BMI1
Interaction	HNRNPU interactions	GTPBP4 ZC3H14 EME1 NVL DIDO1 CHD9 RIOX1 CHD3 SPAG9 CHD4 HNRNPUL1 ZBTB7B SARNP PPWD1 ESF1 NEDD4 UBR5 PHF14 ARHGAP21 TOP2A MOV10	1.36e-04	1035	167	21	int:HNRNPU
Interaction	MYNN interactions	CHD4 APP ZNF710 NOTCH2	1.36e-04	32	167	4	int:MYNN
Interaction	ECT2 interactions	GTPBP4 MYCBP2 NVL SPAG9 HNRNPUL1 MAP7 USP9Y ARPC4 ITPR1 CACTIN DST TJP1 PIK3CB MACF1 ARHGAP21 TOP2A SOAT1 MOV10 NLRP5	1.45e-04	887	167	19	int:ECT2
Interaction	TULP3 interactions	EXOC3 CHD9 CHD2 E2F6 PPFIA3 BCR DCAF5 DST UBR5 FTO ARHGAP21	1.52e-04	346	167	11	int:TULP3
Interaction	DDX23 interactions	GTPBP4 NOP53 NVL CHD2 CHD3 SPAG9 CHD4 ESF1 BMI1 RSBN1 CACTIN UBR5 TOP2A	1.89e-04	480	167	13	int:DDX23
Interaction	MOB3A interactions	NEDD4L APP NEDD4	1.90e-04	14	167	3	int:MOB3A
Interaction	TOP3B interactions	ANKRD13D MYCBP2 C19orf47 GEMIN5 R3HDM2 EDC4 FBXL19 APP ARHGEF11 MAST2 BCR ARPC4 MAPK8IP3 STK10 DST SGSM2 MCM3AP USP40 DIAPH2 PLA2G6 KDM4A ARHGAP21 CEP170B NOTCH2 MOV10 TBCD	1.93e-04	1470	167	26	int:TOP3B
Interaction	ZMYND8 interactions	ECT2L CHD3 CHD4 E2F6 DNAH7 ESF1 ZNF532 NOTCH2	1.97e-04	191	167	8	int:ZMYND8
Interaction	TTN interactions	ANK1 MYCBP2 CHD4 ZBTB7B MAST2 ZNF532 UBR5 AFDN MAP1LC3B TOP2A	2.03e-04	299	167	10	int:TTN
Interaction	CLDN16 interactions	APP TJP1	2.04e-04	3	167	2	int:CLDN16
Interaction	USP7 interactions	TET2 GTPBP4 CFAP91 ZCCHC12 ANK1 NEDD4L CENPB GPR85 APP MAST2 BRWD3 GMPS BMI1 RSBN1 FANCB TENM4 DST IPCEF1 PLXNA4 MACF1 XAF1 UHRF2 BTNL9 TOP2A	2.15e-04	1313	167	24	int:USP7
Interaction	PARP1 interactions	GTPBP4 CENPB NCKAP1 MYCBP2 NOP53 NVL DIDO1 CHD3 CHD4 QRICH1 HNRNPUL1 ESF1 GMPS CDCA2 BMI1 RSBN1 SMARCB1 SENP6 PHF14 MAP1LC3B UHRF2 TOP2A MOV10 TBCD	2.22e-04	1316	167	24	int:PARP1
Interaction	CALM1 interactions	EME1 MYCBP2 MTPAP DENND4C ITPR1 NEDD4 BMI1 DST UBR5 MCM3AP PLA2G6 ATP2B2 ATP2B4 ARHGAP21 MOV10	2.31e-04	626	167	15	int:CALM1
Interaction	SGK3 interactions	NEDD4L NCKAP1 CHD3 CHD4 APP	2.70e-04	69	167	5	int:SGK3
Interaction	SNRNP40 interactions	NOP53 CHD3 QRICH1 HNRNPUL1 APP ZBTB7B PPWD1 CDCA2 RSBN1 CACTIN ZNF532 UBR5 SENP6 TOP2A MOV10	2.78e-04	637	167	15	int:SNRNP40
Interaction	OCLN interactions	RALGAPA1 ARHGAP32 NEDD4L EXOC3 NEDD4 DST TJP1 USP40 MACF1 AFDN ATP2B4 ARHGAP21 NOTCH2	2.81e-04	500	167	13	int:OCLN
Interaction	SORBS3 interactions	HNRNPUL1 FBXL19 PPFIA3 APP ZBTB7B GLRA1 AFDN ARHGAP21	2.88e-04	202	167	8	int:SORBS3
Interaction	PRR16 interactions	NEDD4L APP NEDD4	2.89e-04	16	167	3	int:PRR16
Interaction	MAP3K5 interactions	NEDD4L GEMIN5 SPAG9 APP MAPK8IP3 NEDD4 CEP170B	2.91e-04	153	167	7	int:MAP3K5
Interaction	ARHGEF2 interactions	MYCBP2 DBNL MAP7 USP9Y NEDD4 BMI1 ARHGAP21 CEP170B MOV10	2.93e-04	256	167	9	int:ARHGEF2
Interaction	SLC6A4 interactions	RALGAPA1 CDK18 ARHGAP32 NCKAP1 DBNL PPFIA3 ARPC4 UBR5 MACF1 DLG2 ARHGAP21 CEP170B	2.96e-04	437	167	12	int:SLC6A4
Interaction	SP2 interactions	QRICH1 APP ZBTB7B NOTCH2	2.98e-04	39	167	4	int:SP2
Interaction	SLX4 interactions	GTPBP4 EME1 CENPB NOP53 NVL DIDO1 CHD9 CHD4 APP ESF1 GMPS CDCA2 UBR5 SENP6	3.03e-04	572	167	14	int:SLX4
Interaction	PES1 interactions	GTPBP4 CENPB NOP53 NVL CHD4 APP ESF1 MAP1LC3B MOV10	3.10e-04	258	167	9	int:PES1
Interaction	H2AC4 interactions	EXOC3 CHD9 CHD2 CHD3 CHD4 HNRNPUL1 EDC4 BMI1 UBR5 TJP1 SMARCB1 PHF14 TOP2A	3.15e-04	506	167	13	int:H2AC4
Interaction	NCBP3 interactions	ZC3H14 C19orf47 CHD3 CHD4 APP SARNP BMI1	3.27e-04	156	167	7	int:NCBP3
Interaction	MKI67 interactions	GTPBP4 ZC3H14 TICRR NOP53 NVL DIDO1 RIOX1 CHD3 CHD4 QRICH1 BMI1 DST MAP1LC3B UHRF2 MOV10	3.33e-04	648	167	15	int:MKI67
Interaction	KCNA3 interactions	ADCY10 RALGAPA1 ARHGAP32 NEDD4L NCKAP1 SPEF2 EXOC3 CHD9 CHD2 DENND4C GMPS DST SENP6 MACF1 PYGL AFDN ARHGAP21 NLRP5	3.37e-04	871	167	18	int:KCNA3
Interaction	XRN2 interactions	GTPBP4 NVL CHD3 CHD4 HNRNPUL1 APP PCF11 BMI1 UBR5 MCM3AP MOV10	3.47e-04	381	167	11	int:XRN2
Interaction	LGR4 interactions	NEDD4L MYCBP2 GEMIN5 CHD3 CHD4 EDC4 NEDD4 AFDN ATP2B2	3.47e-04	262	167	9	int:LGR4
Interaction	CAV1 interactions	RALGAPA1 ARHGAP32 EXOC3 APP DENND4C NEDD4 STK10 DST MAP1LC3B2 PIK3CB MACF1 AFDN ATP2B4 ARHGAP21 NOTCH2 MOV10	3.52e-04	724	167	16	int:CAV1
Interaction	THOC7 interactions	CDC42BPG ZC3H14 C19orf47 CHD3 SARNP MOV10	3.77e-04	114	167	6	int:THOC7
Interaction	RHOA interactions	RALGAPA1 GTPBP4 ARHGAP32 NCKAP1 CCDC28A NVL NDUFA6 FBXL19 ARHGEF11 BCR MTPAP ITPR1 STK10 TJP1 DIAPH2 MACF1 DAAM1 MAP1LC3B VPS51 ARHGAP21 NOTCH2 SOAT1	3.82e-04	1199	167	22	int:RHOA
Interaction	NOLC1 interactions	KIF21A CHD3 SPAG9 CHD4 APP BCR UBR5 MAP1LC3B UHRF2 MOV10	3.93e-04	325	167	10	int:NOLC1
Interaction	CSNK1G1 interactions	APP CSNK1G1 BTNL9 NOTCH2	3.98e-04	42	167	4	int:CSNK1G1
Cytoband	Ensembl 112 genes in cytogenetic band chr1p34	FOXO6 MAST2 EDN2 TEKT2 MACF1 KDM4A ZFP69B	1.21e-04	294	170	7	chr1p34
GeneFamily	PHD finger proteins	DIDO1 CHD3 CHD4 FBXL19 PHF14 UHRF2	2.23e-05	90	114	6	88
GeneFamily	PDZ domain containing	ARHGEF11 MAST2 TJP1 DLG2 AFDN ARHGAP21	4.04e-04	152	114	6	1220
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	1.08e-03	8	114	2	939
GeneFamily	E2F transcription factors	E2F7 E2F6	1.08e-03	8	114	2	982
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B4	1.38e-03	9	114	2	1209
GeneFamily	Tudor domain containing	KDM4C KDM4A UHRF2	1.62e-03	37	114	3	780
GeneFamily	PHD finger proteins\|NuRD complex	CHD3 CHD4	2.50e-03	12	114	2	1305
GeneFamily	Helix-turn-helix CENPB type domain containing	CENPB TIGD6	2.94e-03	13	114	2	533
GeneFamily	Rho GTPase activating proteins\|BCH domain containing	STARD13 ARHGAP32 ARHGAP21	3.86e-03	50	114	3	721
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	STARD13 ZC3H14 NCKAP1 MYCBP2 KDM4C NVL CHD9 R3HDM2 SPAG9 ATP8B1 APP MAST2 ITPR1 NEDD4 GMPS PCF11 RSBN1 STK10 DST UBR5 MACF1 PHF14 DAAM1 SPIDR FTO ATP2B4 TOP2A PLCE1	1.28e-12	856	168	28	M4500
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_UP	ERCC5 MYCBP2 DIDO1 CHD2 CHD3 E2F6 PPWD1 DENND4C UBR5 MACF1	3.28e-07	184	168	10	M9005
Coexpression	GSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_2H_UP	TSPOAP1 DBNL PROSER1 DCAF5 ZNF710 CDCA2 SMARCB1 CKAP2L PHF14 HS3ST2	7.06e-07	200	168	10	M6057
Coexpression	GSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN	TET2 CHD9 EDC4 ITGA9 BRWD3 ITPR1 MACF1 PLA2G6	1.23e-05	166	168	8	M6826
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HDA1	ZCCHC12 ANK1 NEDD4L TSPOAP1 KIF21A GPR85 CHD3 APP MAST2 NALCN VASH2 PLXNA4 DAAM1 GPR176	2.58e-05	584	168	14	M39068
Coexpression	GSE22886_IL2_VS_IL15_STIM_NKCELL_DN	CDK18 EXOC3 E2F6 EDC4 NDUFA6 GMPS TEKT2 NDUFAF4	3.92e-05	195	168	8	M4516
Coexpression	GSE11057_NAIVE_CD4_VS_PBMC_CD4_TCELL_UP	DIDO1 RIOX1 CHD3 QRICH1 EDC4 RSBN1 IPCEF1 VPS51	4.36e-05	198	168	8	M3108
Coexpression	RAMALHO_STEMNESS_UP	ZC3H14 ERCC5 ESF1 PCF11 NDUFAF4 TJP1 PPP1R2P1 PLA2G6	5.20e-05	203	168	8	MM1017
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3	TICRR EME1 DDX59 ERCC5 NEDD4L TTC41P KIF21A E2F7 CHD9 CHD4 PPWD1 ESF1 GMPS CDCA2 RSBN1 NDUFAF4 IPCEF1 DIAPH2 CKAP2L MACF1 PHF14 PWWP3B UHRF2 ARHGAP21 TOP2A	1.73e-05	1257	167	25	facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SPEF2 APP NEDD4 DST UBR5 TJP1 DIAPH2 MACF1 AFDN	7.65e-08	200	169	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TICRR EME1 E2F7 EVC MAST2 CDCA2 FANCB CKAP2L TOP2A	7.65e-08	200	169	9	af3dc76b4507bf4edd265169f5dfbbb8a19eb394
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EME1 PRSS55 E2F7 CDCA2 AHRR CKAP2L TOP2A TBCD	1.52e-07	156	169	8	b3f10cd044f24807576e7d56e51df7064dbf6c50
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 CHD9 CHD3 CHD4 NEDD4 IPCEF1 SENP6 MACF1	4.92e-07	182	169	8	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYCBP2 CHD9 CHD3 CHD4 NEDD4 IPCEF1 SENP6 MACF1	4.92e-07	182	169	8	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	ASK452-Epithelial-Ciliated\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP91 SPEF2 KIF21A ECT2L DNAH7 TEKT2 FTO DNAAF1	7.98e-07	194	169	8	5aeb44657ab6f61b1abf98af28d3397d8e44c1aa
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFAP91 SPEF2 E2F7 DNAH7 TEKT2 CKAP2L DNAAF1 TOP2A	8.95e-07	197	169	8	6e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 ARHGAP32 NEDD4L KDM4C DIAPH2 DLG2 SPIDR FTO	9.30e-07	198	169	8	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	PSB-critical-LOC-Epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGAP32 NCKAP1 KIF21A ATP8B1 MAP7 APP TJP1 AFDN	9.66e-07	199	169	8	58dcb0eedafa8629585dc99e53147e2287f49689
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	EDC4 MAP7 ZNF710 SGSM2 CSNK1G1 MTTP PYGL	2.91e-06	162	169	7	ca30d9bf61f4133566fdc91c7996e130ea554d01
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_VISp_Col23a1_Adamts2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CDK18 FOXO6 MAS1 DNAH14 RYR3 HS3ST2 ATP2B4	3.70e-06	168	169	7	3fe432267656aff81b6d92c18d1b6fc0cde73d6a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR EME1 E2F7 CDCA2 TEKT2 CKAP2L TOP2A	4.49e-06	173	169	7	f38bf7584e08d15a6e2c116b7c3551ba475a5e14
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR EME1 E2F7 CDCA2 FANCB CKAP2L TOP2A	4.67e-06	174	169	7	7b318796728001c17b4043d2b033330c7be40c78
ToppCell	T_cells-TFH-like_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	STARD13 ZCCHC12 ANK1 EVC MAP7 CKAP2L TOP2A	5.42e-06	178	169	7	e2ae43e5ec31de6197f2cbd6089f944adbf0a163
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	EME1 GPR85 C19orf47 E2F7 CDCA2 CKAP2L TOP2A	5.62e-06	179	169	7	ec69e1dd897414033ba5b007aa82655a79adca6c
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR EME1 E2F7 CDCA2 FANCB CKAP2L TOP2A	5.83e-06	180	169	7	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	Control-T_cells-Cycling_NK/T_cells\|Control / group, cell type (main and fine annotations)	TICRR E2F7 CDCA2 FANCB CKAP2L UHRF2 TOP2A	6.97e-06	185	169	7	9766216b41ee62bbac4caa25cb98ec5627a24075
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic-Cycling_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	TICRR E2F7 APP CDCA2 DST VASH2 TOP2A	6.97e-06	185	169	7	9d3168c7f0b1d739f78b368969cf5c77ce202b97
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR EME1 E2F7 CDCA2 FANCB CKAP2L TOP2A	7.48e-06	187	169	7	9351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR EME1 IL37 E2F7 CDCA2 CKAP2L TOP2A	7.48e-06	187	169	7	057569c9437219ecc396aa6e673b1178a2273837
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF21A CHD2 SPAG9 CHD4 NDUFA6 ESF1 SENP6	7.75e-06	188	169	7	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	Int-URO-Lymphocyte-T_NK-T_NK_proliferative\|Int-URO / Disease, Lineage and Cell Type	TICRR EME1 KIF21A E2F7 CDCA2 CKAP2L TOP2A	8.30e-06	190	169	7	005967c540418b85311308072a07c684f4296aef
ToppCell	pdx-Tumor_cells-T1\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	TICRR E2F7 MAST2 CDCA2 CKAP2L TOP2A TBCD	8.30e-06	190	169	7	d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell-proliferating_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TICRR EME1 E2F7 ECT2L CDCA2 CKAP2L TOP2A	8.59e-06	191	169	7	15dbc5a03bfab8931c0fd385b0f25874736ae874
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-Proliferating_T_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TICRR EME1 E2F7 ECT2L CDCA2 CKAP2L TOP2A	8.59e-06	191	169	7	45c15f5ce4a207ac944bed65d45f06c1657d1a6d
ToppCell	Hippocampus-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Neurogenesis.Sox4.Hist1h2al)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TICRR EME1 E2F7 CDCA2 LTB4R TOP2A	8.72e-06	126	169	6	6072996987f7b05949adb86c9433e3302c4441d2
ToppCell	ASK452-Epithelial-Ciliated\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP91 SPEF2 KIF21A ECT2L DNAH7 FTO DNAAF1	9.19e-06	193	169	7	c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 PPFIA3 TENM4 SGSM2 PLXNA4 ATP2B2 ATP2B4	9.19e-06	193	169	7	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	EPHX2 NEDD4L KIF21A DIDO1 DNAH14 AFDN DAAM1	9.19e-06	193	169	7	503a979328c68b096680b71359a26f02fafdff35
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 PPFIA3 TENM4 SGSM2 PLXNA4 ATP2B2 ATP2B4	9.19e-06	193	169	7	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPOAP1 PPFIA3 TENM4 SGSM2 PLXNA4 ATP2B2 ATP2B4	9.19e-06	193	169	7	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	PSB-critical-LOC-Epithelial-FOXN4+\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	EME1 E2F7 CDCA2 CKAP2L PYGL TOP2A PLCE1	9.19e-06	193	169	7	b7d9c5bed524423e92f01496a9f8fad11b33a3f7
ToppCell	critical-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CFAP91 SPEF2 ECT2L DNAH7 TEKT2 DIAPH2 DNAAF1	1.09e-05	198	169	7	ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCell	NS-critical-d_07-13\|critical / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGAP32 NEDD4L NCKAP1 KIF21A STEAP4 ATP8B1 TJP1	1.09e-05	198	169	7	a6e11c87b31beffb6af190c64b4ef3ee1d9dab8d
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD4+_CTL\|Int-URO / Disease, condition lineage and cell class	ZC3H14 DDX59 KIF21A DENND4C DSEL DNAAF1 CEP170B	1.09e-05	198	169	7	717735d755745439f97ba1b71785c73945dfa9c5
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	STARD13 ARHGAP32 KDM4C UBR5 DLG2 SPIDR FTO	1.12e-05	199	169	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Bronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TICRR EME1 E2F7 CDCA2 FANCB CKAP2L TOP2A	1.12e-05	199	169	7	1d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	ZCCHC12 MYCBP2 CHD3 VASH2 PLXNA4 AFDN DAAM1	1.12e-05	199	169	7	77b4aa00f14b86ef5db0490be98787e063979541
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NCKAP1 APP NEDD4 DST TJP1 MACF1 AFDN	1.16e-05	200	169	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	control-Epithelial\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGAP32 NCKAP1 KIF21A STEAP4 APP TJP1 AFDN	1.16e-05	200	169	7	f95bbb94e51ac28b1995026c599ec3a34e012916
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	RALGAPA1 ATP8B1 APP BCR NEDD4 DST DAAM1	1.16e-05	200	169	7	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ARHGAP32 NCKAP1 KIF21A APP DST TJP1 AFDN	1.16e-05	200	169	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NCKAP1 APP NEDD4 DST TJP1 MACF1 AFDN	1.16e-05	200	169	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	APP BCR NEDD4 DST TJP1 MACF1 AFDN	1.16e-05	200	169	7	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	Biopsy_IPF-Epithelial-Ciliated\|Biopsy_IPF / Sample group, Lineage and Cell type	CFAP91 SPEF2 KIF21A ECT2L DNAH7 TEKT2 DNAAF1	1.16e-05	200	169	7	bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-T/NK_proliferative\|Int-URO / Disease, condition lineage and cell class	TICRR EME1 KIF21A E2F7 CDCA2 CKAP2L TOP2A	1.16e-05	200	169	7	99acc1ea01288efdd5b166aa20d66735f2bbe543
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	APP NEDD4 DST TJP1 MACF1 AFDN XAF1	1.16e-05	200	169	7	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SPEF2 APP DST TJP1 DIAPH2 MACF1 AFDN	1.16e-05	200	169	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	ARHGAP32 NCKAP1 KIF21A APP DST TJP1 AFDN	1.16e-05	200	169	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	APP BCR NEDD4 DST TJP1 MACF1 AFDN	1.16e-05	200	169	7	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	DIDO1 CHD9 MAP7 ESF1 PCF11 AFDN	1.29e-05	135	169	6	ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	1.72e-05	142	169	6	7bd05d0c0ac2dee0e6cc0f3c531f9154bf300c75
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	1.72e-05	142	169	6	328d08ba2712cd42bb9846ac4d7453ae165b75e2
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	1.72e-05	142	169	6	94774d3e598d074f48146b0b094705dc48af5a1f
ToppCell	Frontal_cortex-Macroglia-POLYDENDROCYTE-P4-Tnr-Polydendrocyte.Tnr.Dlx1_(Dlx1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	1.72e-05	142	169	6	92bf826827b3e3387ad326566556fc90c5c2f4d5
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP91 NEDD4L SPEF2 DNAH7 TEKT2 DNAAF1	2.44e-05	151	169	6	8216462e723fec2797387929dde095370947e10a
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EME1 HTR3A PRKD3 UBR5 CKAP2L TOP2A	2.93e-05	156	169	6	203ef22eb76bd2b829b027c30af0557080f4006c
ToppCell	ASK452-Epithelial-Type_2\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFAP91 C19orf47 GEMIN5 MRM3 AHRR VPS51	2.93e-05	156	169	6	e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRD ZNF710 STK10 FANCB TENM4 ZNF532	3.04e-05	157	169	6	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EME1 E2F7 CDCA2 FANCB CKAP2L TOP2A	3.04e-05	157	169	6	1ccb07a38d3fb606ee5fbc0437655f49baaaa62c
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13D COL11A2 C19orf47 PYGL LTB4R SOAT1	3.15e-05	158	169	6	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD13D COL11A2 C19orf47 PYGL LTB4R SOAT1	3.15e-05	158	169	6	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KDM4C ITGA9 ARHGEF11 AHRR PIK3CB	3.61e-05	98	169	5	95162072f3afc95e46f29db3d79ebd930bc09726
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EME1 E2F7 MAST2 CDCA2 CKAP2L TOP2A	3.88e-05	164	169	6	4ef776d1bab4103d42d3a4f22cdfb49e8d2bc5a0
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPR137 ZC3H14 DNAH7 NEDD4 FSIP2 MOV10	4.01e-05	165	169	6	436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	GPR137 ZC3H14 DNAH7 NEDD4 FSIP2 MOV10	4.01e-05	165	169	6	242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCell	facs-Spleen-nan-18m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 CDK18 ANK1 CKAP2L ATP2B4 TOP2A	4.15e-05	166	169	6	8d535fab019356894b4dad3fbdbc4d2ad3e16082
ToppCell	facs-Spleen-nan-18m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 CDK18 ANK1 CKAP2L ATP2B4 TOP2A	4.15e-05	166	169	6	f56b1c0d6cb5353a16a2598bda905287f16d2c39
ToppCell	facs-Spleen-nan-18m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EPHX2 CDK18 ANK1 CKAP2L ATP2B4 TOP2A	4.15e-05	166	169	6	a5074c96c6561273029aceb93402a7e038140f50
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	STARD13 MAS1 RYR3 AHRR PLXNA4 DSEL	4.44e-05	168	169	6	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EME1 CFAP91 E2F7 CDCA2 CKAP2L HES5	4.59e-05	169	169	6	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	343B-Lymphocytic-CD4_T-cell-Proliferating_T_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	TICRR MAP7 RYR3 CDCA2 CKAP2L TOP2A	4.90e-05	171	169	6	4ccd88cf812dd8bfdc55159c6f504e9c84e4f4fc
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	ANK1 HTR3A APP STK10 MELTF DST	5.39e-05	174	169	6	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	droplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TICRR PPFIA3 MAST2 CDCA2 CKAP2L TOP2A	5.57e-05	175	169	6	a6913f992a1ea20b43e5adeca3ede3a6fda820ad
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CDK18 FOXO6 MAS1 DNAH14 HS3ST2 ATP2B4	5.57e-05	175	169	6	c227fc5d1ccb69b82a96a6354913cafaf27d0eec
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DDX59 ERCC5 NEDD4L EDC4 MAP7 LTB4R	5.57e-05	175	169	6	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR E2F7 CDCA2 FANCB CKAP2L TOP2A	5.57e-05	175	169	6	876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	STARD13 TICRR EME1 CDCA2 CKAP2L TOP2A	5.75e-05	176	169	6	8813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma\|TCGA-Brain / Sample_Type by Project: Shred V9	TSPOAP1 CHD2 SPAG9 BCR DST NALCN	5.93e-05	177	169	6	e8ab340b20cd41554c3841fe980e078e878af35f
ToppCell	facs-Heart-RA-18m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPB MYCBP2 DBNL CHD3 HNRNPUL1 SENP6	6.12e-05	178	169	6	b505e2550860e777535ee95f29c936242fd607f1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ARHGAP32 CHD2 SGSM2 IPCEF1 MACF1 ARHGAP21	6.31e-05	179	169	6	6e965e424eebef50f0202cff75f458be395cfca1
ToppCell	droplet-Bladder-Unstain-18m-Epithelial-granulocyte-monocyte_progenitor\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR EME1 ANK1 CDCA2 DNAAF1 TOP2A	6.31e-05	179	169	6	804aa3899585fc7e662eff9f6d41f48655f16dd6
ToppCell	Control-Developping_Plasmablast\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	6.31e-05	179	169	6	9383568f78b07b8cca72ece5d15fea209aa54ea9
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	E2F7 TEKT2 FTO DNAAF1 TOP2A PLCE1	6.51e-05	180	169	6	0c146e80d55d18b6988dd21b1da635801bd3140c
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	E2F7 TEKT2 FTO DNAAF1 TOP2A PLCE1	6.51e-05	180	169	6	e9af22beae2f3c7fe213b4e19df84abfd2453433
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	E2F7 TEKT2 FTO DNAAF1 TOP2A PLCE1	6.51e-05	180	169	6	11455ba704ac73f69b474845136cfecec6a88349
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	6.51e-05	180	169	6	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	IIH-cycling-\|IIH / Condition, Cell_class and T cell subcluster	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	6.71e-05	181	169	6	7f4fed9e296bc22cb5a1e6c8e3c4b641e97c3078
ToppCell	IIH-cycling\|IIH / Condition, Cell_class and T cell subcluster	TICRR EME1 E2F7 CDCA2 CKAP2L TOP2A	6.71e-05	181	169	6	ec3e782ce93dcfe1a54fb7284e4e39063614b0e2
ToppCell	3'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-NK_cells_L.1.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TICRR EME1 CDCA2 IPCEF1 CKAP2L TOP2A	6.71e-05	181	169	6	e4dbc09f0210de465d8347969b301c22463a2b7d
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APP CDCA2 PIK3CB CKAP2L LTB4R TOP2A	6.71e-05	181	169	6	566249e04dd491e6287ad2101b7b1ab11031ed8b
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP91 E2F7 ECT2L DNAH7 TEKT2 DNAAF1	6.71e-05	181	169	6	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	APP CDCA2 PIK3CB CKAP2L LTB4R TOP2A	6.71e-05	181	169	6	db9528dc7cb0230e4c36cb27da69102c588c7ee9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_G2M\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TICRR EME1 IL37 CDCA2 CKAP2L TOP2A	6.92e-05	182	169	6	336cd05e46a741185ce3c59ee67a4b07fa6a5101
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFAP91 SPEF2 ECT2L DNAH7 TEKT2 DNAAF1	6.92e-05	182	169	6	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR NCKAP1 CDCA2 CKAP2L HES5 TOP2A	6.92e-05	182	169	6	39f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-5\|TCGA-Liver / Sample_Type by Project: Shred V9	TICRR EME1 CDCA2 FANCB CKAP2L TOP2A	7.13e-05	183	169	6	f604a8b62c7088fad8365dbf8d910fc980bd3ba8
ToppCell	Striatum-Macroglia-POLYDENDROCYTE-P5\|Striatum / BrainAtlas - Mouse McCarroll V32	TICRR E2F7 SARNP CDCA2 CKAP2L TOP2A	7.13e-05	183	169	6	f20b0d71f857ac35868fd80531050ad8b6091716
ToppCell	Frontal_cortex-Neuronal-Excitatory\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MYCBP2 MAS1 R3HDM2 IPCEF1 HS3ST2 ATP2B4	7.35e-05	184	169	6	6e17c8151d6dc543de16d804db956c63c3fda414
ToppCell	Ciliated_cells-B-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CFAP91 SPEF2 ECT2L DNAH7 TEKT2 DNAAF1	7.57e-05	185	169	6	f012c243343e1d1956db19b34d062e9b13de2b2a
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SPAG9 DST TJP1 SENP6 MACF1	9.13e-05	50	99	5	GAVISH_3CA_MALIGNANT_METAPROGRAM_4_CHROMATIN
Drug	Sulfanilamide [63-74-1]; Up 200; 23.2uM; MCF7; HT_HG-U133A	GPR137 EPHX2 ANK1 TSPOAP1 MAPK8IP3 ITPR1 PLA2G6 XAF1 SPIDR ATP2B2 PLCE1	2.14e-07	196	166	11	6810_UP
Drug	Cimetidine [51481-61-9]; Up 200; 15.8uM; MCF7; HT_HG-U133A	GPR137 CHD9 APP ARHGEF11 MAST2 MAPK8IP3 ITPR1 PRKD3 STK10 MCM3AP	2.02e-06	198	166	10	1464_UP
Drug	ICI 182,780; Down 200; 1uM; MCF7; HT_HG-U133A	GTPBP4 CHD9 APP TSEN2 NDUFAF4 TJP1 SGSM2 DAAM1 SOAT1	8.24e-06	183	166	9	6925_DN
Drug	Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ARHGAP32 CHD9 CHD3 BCR RSBN1 UBR5 PIK3CB DIAPH2 ATP2B4	1.02e-05	188	166	9	4845_DN
Drug	Meptazinol hydrochloride [59263-76-2]; Down 200; 14.8uM; MCF7; HT_HG-U133A	ARHGAP32 EDC4 PPFIA3 MAST2 BCR CACTIN MACF1 PLA2G6 TBCD	1.49e-05	197	166	9	4774_DN
Drug	Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; PC3; HT_HG-U133A	KDM4C PROSER1 PPFIA3 RBM48 APP ARHGEF11 ZNF710 CACTIN VASH2	1.55e-05	198	166	9	6297_DN
Drug	Calcium	EPHX2 NEDD4L REN ATP8B1 APP EDN2 RYR3 ITPR1 NEDD4 TJP1 PIK3CB PYGL PLA2G6 ATP2B4	1.62e-05	493	166	14	ctd:D002118
Disease	red blood cell density measurement	STARD13 RALGAPA1 TET2 ANK1 EXOC3 R3HDM2 CHD4 ATP8B1 ARHGEF11 MAST2 PRKD3 DST UBR5 AFDN PLA2G6 KDM4A UHRF2 ATP2B4	2.81e-06	880	167	18	EFO_0007978
Disease	hypertension (is_implicated_in)	EPHX2 REN ITGA9 EDN2 MTTP FTO MOV10	6.02e-06	121	167	7	DOID:10763 (is_implicated_in)
Disease	Bipolar Disorder	HTR3A DBNL REN APP ITGA9 BCR ITPR1 NEDD4 TENM4 DLG2 PLA2G6	9.24e-05	477	167	11	C0005586
Disease	Liddle syndrome (implicated_via_orthology)	NEDD4L NEDD4	1.90e-04	4	167	2	DOID:0050477 (implicated_via_orthology)
Disease	urate measurement, bone density	DDX59 PRSS55 QRICH1 DNAH14 ITPR1 FSIP2 USP40 PLXNA4 DLG2 FTO ATP2B2 ATP2B4	2.24e-04	619	167	12	EFO_0003923, EFO_0004531
Disease	insomnia measurement	TET2 NEDD4L MYCBP2 UBR5 SGSM2 DLG2 PHF14 ATP2B2 ATP2B4 ARHGAP21	2.29e-04	443	167	10	EFO_0007876
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B4	4.71e-04	6	167	2	DOID:0050429 (implicated_via_orthology)
Disease	sleep apnea measurement	ANK1 IL37 E2F7 DENND4C ATP2B4	5.29e-04	116	167	5	EFO_0007817
Disease	melanoma	ERCC5 KDM4C MTPAP MELTF DLG2 KDM4A FTO	5.51e-04	248	167	7	C0025202
Disease	Epileptic encephalopathy	NEDD4L CHD2 RYR3	6.46e-04	30	167	3	C0543888
Disease	CHARGE syndrome (implicated_via_orthology)	CHD9 CHD2	6.56e-04	7	167	2	DOID:0050834 (implicated_via_orthology)
Disease	serum gamma-glutamyl transferase measurement	CDK18 NEDD4L CHD9 ATP8B1 FBXL19 ITGA9 ARHGEF11 DCAF5 ITPR1 TENM4 TJP1 ARHGAP21 NOTCH2 PLCE1	7.33e-04	914	167	14	EFO_0004532
Disease	cysteine-rich with EGF-like domain protein 1 measurement	ARPC4 ATP2B2 ATP2B4	7.83e-04	32	167	3	EFO_0021870
Disease	hemoglobin A1 measurement	TET2 ZCCHC12 ANK1 HNRNPUL1 MAST2 MELTF MACF1 FTO ATP2B4 NOTCH2	7.97e-04	520	167	10	EFO_0007629
Disease	cancer (implicated_via_orthology)	ARPC4 DST PIK3CB MACF1 DLG2 TOP2A NOTCH2	8.69e-04	268	167	7	DOID:162 (implicated_via_orthology)
Disease	preeclampsia	MYCBP2 TENM4 FTO PLCE1	1.02e-03	78	167	4	EFO_0000668
Disease	Intellectual Disability	RALGAPA1 ZC3H14 CHD3 QRICH1 TSEN2 BRWD3 MAPK8IP3 MACF1 TBCD	1.06e-03	447	167	9	C3714756
Disease	alopecia areata (is_marker_for)	KDM4C KDM4A	1.39e-03	10	167	2	DOID:986 (is_marker_for)
Disease	familial hypercholesterolemia (is_implicated_in)	EPHX2 MTTP	1.39e-03	10	167	2	DOID:13810 (is_implicated_in)
Disease	ankyrin-2 measurement	DDX59 ATP2B4	1.39e-03	10	167	2	EFO_0021874
Disease	attention function measurement	E2F7 ITPR1 DST DLG2 FTO	1.58e-03	148	167	5	EFO_0007636
Disease	Macrocephaly	CHD3 BRWD3	1.69e-03	11	167	2	C0221355
Disease	gastric adenocarcinoma (is_implicated_in)	UBR5 PLCE1	1.69e-03	11	167	2	DOID:3717 (is_implicated_in)
Disease	birth weight	TET2 ANK1 ATP8B1 ZBTB7B TENM4 PLA2G6 ARHGAP21 PLCE1	2.05e-03	399	167	8	EFO_0004344
Disease	Squamous cell carcinoma of esophagus	ZCCHC12 DIDO1 NOTCH2 PLCE1	2.11e-03	95	167	4	C0279626
Disease	economic and social preference	CDC42BPG PLXNA4 ATP2B2 ATP2B4	2.28e-03	97	167	4	EFO_0004827
Disease	adipic acid mesurement	KDM4C MELTF	2.38e-03	13	167	2	EFO_0010455
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRD NCKAP1 DLG2	2.71e-03	49	167	3	DOID:0060037 (implicated_via_orthology)
Disease	Weight Gain	APP TSEN2 PRKD3 FTO	2.73e-03	102	167	4	C0043094
Disease	coronary artery disease	TET2 CDK18 FOXO6 TTC41P R3HDM2 CHD2 QRICH1 HNRNPUL1 MAPK8IP3 NEDD4 RSBN1 FTO ARHGAP21 TBCD PLCE1	3.33e-03	1194	167	15	EFO_0001645
Disease	abdominal adipose tissue measurement	CDCA2 FTO ATP2B4	3.39e-03	53	167	3	EFO_0803316
Disease	Drugs used in diabetes use measurement	ANK1 MYCBP2 DNAH7 MACF1 FTO NOTCH2	3.40e-03	255	167	6	EFO_0009924
Disease	preeclampsia, hypertension, pregnancy-induced	FTO PLCE1	3.63e-03	16	167	2	EFO_0000668, MONDO_0024664
Disease	Glioblastoma Multiforme	CDC42BPG PRKD3 BMI1 NOTCH2	3.71e-03	111	167	4	C1621958
Disease	posterior cingulate cortex volume measurement	KDM4C PYGL	4.10e-03	17	167	2	EFO_0010324
Disease	sphingosine 1-phosphate measurement	ITPR1 FTO	4.59e-03	18	167	2	EFO_0800185
Disease	essential hypertension (is_implicated_in)	REN FTO	4.59e-03	18	167	2	DOID:10825 (is_implicated_in)
Disease	alcohol use disorder (implicated_via_orthology)	KDM4C RIOX1 RYR3 PIK3CB NOTCH2	5.15e-03	195	167	5	DOID:1574 (implicated_via_orthology)
Disease	alkaline phosphatase measurement	RALGAPA1 TET2 NEDD4L PRSS55 EVC CHD3 ITPR1 RSBN1 MACF1 PYGL PLA2G6 ARHGAP21 PLCE1	5.26e-03	1015	167	13	EFO_0004533
Disease	free androgen index	TET2 R3HDM2 REN ATP2B2 ATP2B4 ARHGAP21 SOAT1	5.59e-03	374	167	7	EFO_0007005
Disease	visual cortical surface area measurement	DAAM1 MOV10	5.66e-03	20	167	2	EFO_0004771
Disease	unipolar depression, bipolar disorder, schizophrenia	E2F7 FTO	5.66e-03	20	167	2	EFO_0003761, MONDO_0004985, MONDO_0005090

Protein segments in the cluster

Peptide	Gene	Start	Entry
KMRSALLRAKPRADT	AHRR	286	A9YTQ3
FTRTISNPEVVMKRR	AFDN	211	P55196
QMPAFRNRTKLVKDD	BTNL9	96	Q6UXG8
IGRPIEMSSKVQRFK	ANKRD13D	346	Q6ZTN6
VPAKRRRVTAEMEGK	C19orf47	196	Q8N9M1
RMVDPKKAAQIRSQV	APP	516	P05067
REFSLKRMPSRKQTG	BCR	1036	P11274
MKNFKRRFSLSVPRT	CDK18	6	Q07002
NRLAMPVKVRDSSRE	ANK1	1321	P16157
FIPEGVVARRKRMET	GTPBP4	376	Q9BZE4
RLPEKVKSDRSVFMN	HTR3A	191	P46098
MKRSRKAENVPRSRS	ARHGEF11	621	O15085
TMKFRDRPVKFTERS	BRWD3	301	Q6RI45
MARRGKKPVVRTLED	BTBD11	1	A6QL63
LFAKRQQEAMREPRS	EDN2	156	P20800
KCREMIPAFRTFLKR	ECT2L	676	Q008S8
KFSNRAKNLLPRRTM	ADCY10	1441	Q96PN6
SRKPTMAEARAVSRK	CEP170B	1206	Q9Y4F5
PLRNKDFTTKREMVV	DIAPH2	126	O60879
RVFRPRDRDEMVKKV	ATP2B2	646	Q01814
AVPFKNKDRDDMVRT	ATP2B4	611	P23634
FNSDRKRMSIIVRTP	ATP8B1	596	O43520
RLRKVPRFKTMFSNL	CFAP91	66	Q7Z4T9
SPQREKLERFKRMCQ	FBXL19	301	Q6PCT2
EFLVNTLKKNPRDRM	R3HDM2	156	Q9Y2K5
VDRFMPRTTQLQERK	RBM48	271	Q5RL73
RVKARSVPQHRMKEF	QRICH1	16	Q2TAL8
MLRKSSFPETEEKVR	TSPOAP1	146	O95153
MKSRKAREQEAREPV	EDC4	1156	Q6P2E9
PKREVASKDMERRIV	NVL	371	O15381
QQRREMLKDPFVRSK	CDC42BPG	1421	Q6DT37
PTAQRKRFTRVEMAR	SPAG9	496	O60271
RASRENPAMQEKKRS	SPAG9	536	O60271
VALRPTNMDRERDKF	KIAA0895L	141	Q68EN5
MPSEKTFKQRRTFEQ	MAP1LC3B	1	Q9GZQ8
KKQRMTRRSLPGEQE	NOTCH2	1601	Q04721
EAPRRIFNMSRDTKL	HS3ST2	186	Q9Y278
RFKSFQRRNMIEPRE	NOP53	441	Q9NZM5
KVVLTRAFKDEMQPR	MAS1	296	P04201
AVVRRTMERSQKPKQ	MAP7	141	Q14244
ESDKIPMAQRRRFTR	MAPK8IP3	511	Q9UPT6
NDIPNKFEMKLRRAT	NEDD4	956	P46934
VPKVGRVERKMSRNN	GPR176	491	Q14439
DKPFSIKIMRTSNRR	MGAM2	176	Q2M2H8
EVVFSKPNRERQKLM	ITPR1	496	Q14643
KSPVKRRRMQSSADL	DST	1381	Q03001
VFKAKVKRRPEMSRG	GPR137	121	Q96N19
MKRTPTAEEREREAK	FTO	1	Q9C0B1
PEEREKKRQFEMRRT	PPP1R2P1	131	Q96PQ5
RKMFREKDLRGVTPD	PPFIA3	1131	O75145
RRAKVAPAERMSKFL	HVCN1	11	Q96D96
REKDERQRTTKPMAQ	CSNK1G1	6	Q9HCP0
TARKKLRRQMRAFPA	MCM3AP	1251	O60318
RKFLRSKMDIPNTFQ	BMI1	176	P35226
MEERKVKRRSPKSFS	CCDC28A	91	Q8IWP9
MFVPRSLKIKRNAND	DDX59	1	Q5T1V6
VSPFERQRTKEMDKV	FSIP2	3941	Q5CZC0
EIMSDQRFRRVAKDP	ESF1	6	Q9H501
VKSPRIECSKTRREM	ESF1	196	Q9H501
KEPRRFASEMKQCVR	PLXNA4	546	Q9HCM2
DILRFEMPASKIVRR	MTTP	581	P55157
KEFMTLTLSRPVFRK	CSNKA2IP	656	A0A1B0GTH6
FVKPIFSRDMNEAKR	NDUFA6	16	P56556
KTPRRRAVSMDNGAK	FOXO6	176	A8MYZ6
IQMPKKTRRSVDGSR	COL11A2	1506	P13942
AMRRRQKTTREDKPS	DCAF5	586	Q96JK2
PKRVKSRLSVASDMR	KDM4A	1011	O75164
KISMDIFVRKFQPDR	KDM4C	316	Q9H3R0
SEKSRLPERITKFMV	PRKD3	666	O94806
KVSRPRAEMDVRNAI	GABRD	346	O14764
VFFLPVREMQRKKES	NLRP5	316	P59047
DKIPKRRFSEMQNER	MTPAP	56	Q9NVV4
RRESRARQKVKGPVM	ARHGAP32	1756	A7KAX9
RMKIRPFDKNTDIRI	OOSP4B	21	A0A2R8Y4Y8
MDRSSKRRQVKPLAA	PHF14	1	O94880
EREKPGVESMRKNRL	NCKAP1	656	Q9Y2A7
VESQQKSPGKRRRML	MACF1	1361	Q9UPN3
DQRKPRMSSDAKEFI	MACF1	2856	Q9UPN3
PMNARVKSKREKREV	MACF1	2971	Q9UPN3
RPFVSQKLRTKAMAR	LTB4R	121	Q15722
RPIEDLFRVNMSEKK	PROSER1	101	Q86XN7
RRMVFDRGTKVFVQK	FANCB	46	Q8NB91
RRMKKTEEERPQETT	PCF11	556	O94913
QFMSRAKVKVDPALR	ITGA9	936	Q13797
LRTKPMRFVTRFIDL	DAAM1	141	Q9Y4D1
MGPKRRQLTFREKSR	CENPB	1	P07199
KAKERGERNIPRVMS	CHD9	536	Q3L8U1
MKLAAQKESARRPFI	IL37	141	Q9NZH6
IFDKAISARKINRPM	EPHX2	91	P34913
RQKPRRKTQGFLTMS	IPCEF1	16	Q8WWN9
DRTPRKRISKTLNMT	GMPS	316	P49915
VSMRKALKVKRPRFD	E2F6	51	O75461
KENIFVDRSRMAPKT	E2F7	31	Q96AV8
QETFSICKERMRPVK	CHD2	1466	O14647
RRLKADVFKNMPAKT	CHD3	966	Q12873
GRREEKTEKPRFMFN	CHD3	1696	Q12873
DLPAFKTIRREFMRL	DNAH7	3336	Q8WXX0
KERPARSVMESRTKL	DIDO1	771	Q9BTC0
RVLFEMKTARIKPNA	DENND4C	841	Q5VZ89
FSVFMPKKLNIVRRA	DNAH14	3371	Q0VDD8
KERFPKATAQMEERL	MAST2	321	Q6P0Q8
NMRKRKRVTFGEDLS	CDCA2	386	Q69YH5
REDRGPRMTKSSLQK	DNAAF1	81	Q8NEP3
DRRKMKPVQFVAAVS	GPR85	211	P60893
LMKAFETPEEKRARR	CACTIN	156	Q8WUQ7
EEMGVIPSKRRVERK	DLG2	591	Q15700
RKNAALVTRMKAQRP	EME1	231	Q96AY2
SPSRRRKREVQMSKD	EVC	81	P57679
MQKRISFRSPEERKE	EXOC3	611	O60645
RRLKADVFKNMPSKT	CHD4	956	Q14839
FKRRESLPEQRSQMK	DSEL	961	Q8IZU8
HPREIFKQKERAMST	DBNL	256	Q9UJU6
RKMRPFEGFQRKAIV	HNRNPUL1	516	Q9BUJ2
KSPFKRRRSMNEIKN	RSBN1	546	Q5VWQ0
MAEAVFHAPKRKRRV	TSEN2	1	Q8NCE0
MESKIPVEDNKRFTR	SPEF2	1176	Q9C093
PTRARAKSFLKRMET	STARD13	251	Q9Y3M8
KMSLRNRLSKSRENP	SOAT1	6	P35610
EKVREASVGPQRKRM	TIGD6	56	Q17RP2
DMAVAFRRQRLKPEI	MELTF	381	P08582
EIPQTERMQKRAERF	SARNP	96	P82979
ERMQKRAERFNVPVS	SARNP	101	P82979
PCMSIDFRDIKKRTR	FER1L5	21	A0AVI2
RFPEKRRMKLGSDIS	MOV10	86	Q9HCE1
SVMTIVKSRPFREKQ	MRM3	106	Q9HC36
SFQKILPDRMKAARD	PWWP3B	536	Q5H9M0
TRAVRKMRKFPDQRQ	PLCE1	1006	Q9P212
QNLSRDMKSFPRKVL	SPATA31A6	676	Q5VVP1
FKRIFLKRMPSIRES	REN	31	P00797
SKSPEEMRKLFIQRA	GLRA1	406	P23415
DRKVRIFRFVTGKLM	PPWD1	301	Q96BP3
TDMKEFTKRRRTLFE	ERCC5	206	P28715
FPKLRKRSSIRSVDM	SGSM2	391	O43147
INRNRMGRDKKRTFP	SMARCB1	151	Q12824
MDTRRKLTVPAERFV	TEKT2	391	Q9UIF3
EMRASPKISRKCANR	MYCBP2	2981	O75592
NRAEREISKMKPSVA	NDUFAF4	16	Q9P032
RKPAFILGSMRDEKR	PLA2G6	461	O60733
KDPEVNEFRRKMRKF	PIK3CB	141	P42338
KPVVEKMRRDRINSS	HES5	21	Q5TA89
DPRRTAFMEKVRVLV	RIOX1	471	Q9H6W3
MLSKGRSPRRKQVQT	SMLR1	1	H3BR10
MRAENFFILRRKPVE	ARPC4	96	P59998
MKFITPVRRSSRIER	CKAP2L	681	Q8IYA6
TLEMNVKDLRPRART	UHRF2	221	Q96PU4
PRNVRAVMKRVVEDT	VPS51	606	Q9UID3
PDSRRTFTKRLMLEK	ZNF532	1091	Q9HCE3
RMKKRSRNTLDSEVP	TICRR	1086	Q7Z2Z1
DSQDKLVRKRRSQMP	ZBTB7B	331	O15156
MKRRQDVSPNRDFLT	RALGAPA1	1156	Q6GYQ0
MPSEKTFKQRRTFEQ	MAP1LC3B2	1	A6NCE7
ARQIMERLIDPRTKS	SPIDR	216	Q14159
TALRRQVRPMSDKVA	KIF21A	831	Q7Z4S6
KQRKRAVVACFRMAP	RYR3	3481	Q15413
RKSRPVSMDARIQVA	STK10	411	O94804
MEKDVRPKTRSINRF	XAF1	206	Q6GPH4
KRLTEANQRMAKFPE	GEMIN5	1436	Q8TEQ6
VKMIDLSAFSRKPRT	ZNF710	156	Q8N1W2
LSMPKRRKFLTDRVD	ZNF654	1061	Q8IZM8
RARRMDLAPQTISDK	TTC41P	1161	Q6P2S7
MDVKERKPYRSLTRR	TENM4	1	Q6N022
TVTLPRKARMKDQFG	SENP6	396	Q9GZR1
KKDNTFRMAISIPNR	STEAP4	231	Q687X5
RRAELMDKPLTFRTL	VASH2	211	Q86V25
PAIERSVRKQNVKFM	USP9Y	1986	O00507
KRRRKEKMEAQCSPV	nan	26	Q1RN00
FNAEKRRTSVKQKPM	PRSS55	306	Q6UWB4
PQSVLTRVKMFENKR	TJP1	1261	Q07157
EPRRAATKTKFTMDL	TOP2A	1316	P11388
NRFEKRINVKSEVMP	ZFP69B	226	Q9UJL9
SRKKPVLSARNSRMF	nan	26	A8MUA0
VSRFITRPDVKQSKM	TBCD	211	Q9BTW9
KQRNRLEPMDTIFVK	ARHGAP21	91	Q5T5U3
VLSSFRRKVRMLAEP	TET2	1446	Q6N021
VALFPKDVDRLRRMS	PYGL	416	P06737
TAIPKEDMRKTFREQ	USP40	701	Q9NVE5
MEDENFRKRKLPVVS	ZC3H14	286	Q6PJT7
FIKRKRPKRSESMVE	ZCCHC12	226	Q6PEW1
VVPFSQRKKMLEKAR	UBR5	496	O95071
PKIRESFMKQFIDRQ	NALCN	656	Q8IZF0
SYRRIMSVKRPDVLK	NEDD4L	631	Q96PU5