Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	transmembrane transporter activity	GABRG3 CACNA1E SLC25A18 PIEZO1 SLC2A14 GLRA3 CEACAM6 SLC39A4 SLC12A8 NDUFB5 SLC1A2 SLC22A6 SLC7A2 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM APOL3 NIPAL1 SLC9A7 SLC25A44 DISP2 NIPA2 SLC14A2 MFSD10	1.26e-07	1180	147	27	GO:0022857
GeneOntologyMolecularFunction	transporter activity	GABRG3 CACNA1E SLC25A18 PIEZO1 SLC2A14 GLRA3 CEACAM6 SLC39A4 SLC12A8 NDUFB5 SLC1A2 SLC22A6 SLC7A2 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM APOL3 NIPAL1 SLC9A7 SLC25A44 DISP2 NIPA2 SLC14A2 MFSD10	7.25e-07	1289	147	27	GO:0005215
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	GABRG3 CACNA1E SLC25A18 GLRA3 SLC39A4 SLC12A8 NDUFB5 SLC1A2 SLC22A6 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM APOL3 NIPAL1 SLC9A7 NIPA2	3.12e-06	758	147	19	GO:0015318
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	GABRG3 CACNA1E SLC25A18 PIEZO1 GLRA3 SLC39A4 SLC12A8 NDUFB5 SLC1A2 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM APOL3 NIPAL1 SLC9A7 NIPA2	5.97e-06	793	147	19	GO:0015075
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC25A18 SLC2A14 CEACAM6 SLC39A4 SLC1A2 SLC22A6 SLC7A2 MFSD2A SLC5A6 SLC25A44 MFSD10	1.14e-05	293	147	11	GO:0008514
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC25A18 SLC39A4 SLC12A8 NDUFB5 SLC1A2 MFSD2A ATP2C1 SLC41A3 SLC5A6 GHITM SLC9A7	1.46e-05	301	147	11	GO:0022853
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	CACNA1E SLC25A18 PIEZO1 SLC39A4 SLC12A8 NDUFB5 SLC1A2 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM NIPAL1 SLC9A7 NIPA2	3.20e-05	664	147	16	GO:0008324
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	CACNA1E SLC39A4 SLC12A8 SLC1A2 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM NIPAL1 SLC9A7 NIPA2	4.11e-05	465	147	13	GO:0046873
GeneOntologyMolecularFunction	ubiquitin-like modifier activating enzyme activity	UBA1 UBA7 UBA6	4.52e-05	10	147	3	GO:0008641
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	CACNA1E SLC25A18 SLC39A4 SLC12A8 NDUFB5 SLC1A2 MFSD2A ATP2C1 KCNA4 SLC41A3 SLC5A6 GHITM NIPAL1 SLC9A7 NIPA2	6.20e-05	627	147	15	GO:0022890
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC25A18 SLC39A4 SLC12A8 SLC1A2 SLC22A6 MFSD2A SLC41A3 SLC5A6 GHITM SLC9A7	7.00e-05	296	147	10	GO:0015291
GeneOntologyMolecularFunction	carboxylic acid transmembrane transporter activity	SLC25A18 CEACAM6 SLC1A2 SLC22A6 SLC7A2 MFSD2A SLC5A6 SLC25A44	1.52e-04	207	147	8	GO:0046943
GeneOntologyMolecularFunction	organic acid transmembrane transporter activity	SLC25A18 CEACAM6 SLC1A2 SLC22A6 SLC7A2 MFSD2A SLC5A6 SLC25A44	1.57e-04	208	147	8	GO:0005342
GeneOntologyMolecularFunction	neuregulin receptor activity	ERBB3 ERBB4	1.61e-04	3	147	2	GO:0038131
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC25A18 SLC39A4 SLC12A8 NDUFB5 SLC1A2 SLC22A6 MFSD2A ATP2C1 SLC41A3 SLC5A6 GHITM SLC9A7	2.19e-04	477	147	12	GO:0022804
GeneOntologyMolecularFunction	ligase activity, forming carbon-sulfur bonds	AASDH UBA1 UBA7 UBA6	2.31e-04	41	147	4	GO:0016877
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC25A18 SLC39A4 SLC12A8 SLC1A2 MFSD2A SLC5A6	2.52e-04	119	147	6	GO:0015294
GeneOntologyMolecularFunction	magnesium ion transmembrane transporter activity	SLC41A3 NIPAL1 NIPA2	2.94e-04	18	147	3	GO:0015095
GeneOntologyMolecularFunction	ubiquitin activating enzyme activity	UBA1 UBA6	3.20e-04	4	147	2	GO:0004839
GeneOntologyMolecularFunction	neuregulin binding	ERBB3 ERBB4	7.92e-04	6	147	2	GO:0038132
GeneOntologyMolecularFunction	symporter activity	SLC25A18 SLC39A4 SLC12A8 SLC1A2 MFSD2A SLC5A6	8.62e-04	150	147	6	GO:0015293
GeneOntologyMolecularFunction	monoatomic anion transmembrane transporter activity	GABRG3 GLRA3 SLC12A8 SLC1A2 SLC5A6 APOL3	8.92e-04	151	147	6	GO:0008509
GeneOntologyMolecularFunction	inorganic anion transmembrane transporter activity	GABRG3 GLRA3 SLC12A8 SLC22A6 SLC5A6 APOL3	1.69e-03	171	147	6	GO:0015103
GeneOntologyBiologicalProcess	import across plasma membrane	CACNA1E SLC39A4 SLC12A8 WNK1 SLC1A2 SLC7A2 PER2 SLC5A6 SLC9A7 WNK2	6.91e-06	230	149	10	GO:0098739
GeneOntologyCellularComponent	synaptic membrane	GABRG3 CACNA1E ERBB3 ERBB4 SIGMAR1 SLC2A14 GLRA3 LRRTM3 MAGEE1 CSMD2 SLC1A2 PTPRA KCNA4 PTPRZ1 LRFN5 SLITRK5 SCRIB ENO2	2.11e-07	583	150	18	GO:0097060
GeneOntologyCellularComponent	postsynaptic membrane	GABRG3 CACNA1E ERBB3 ERBB4 SIGMAR1 GLRA3 LRRTM3 MAGEE1 CSMD2 KCNA4 PTPRZ1 LRFN5 SLITRK5 SCRIB	1.38e-06	405	150	14	GO:0045211
GeneOntologyCellularComponent	postsynaptic specialization membrane	ERBB4 SIGMAR1 GLRA3 LRRTM3 CSMD2 PTPRZ1 LRFN5 SLITRK5 SCRIB	1.52e-05	201	150	9	GO:0099634
GeneOntologyCellularComponent	postsynaptic density membrane	ERBB4 SIGMAR1 LRRTM3 CSMD2 PTPRZ1 LRFN5 SLITRK5 SCRIB	1.81e-05	157	150	8	GO:0098839
Domain	E1_4HB	UBA1 UBA7 UBA6	4.68e-07	3	146	3	PF16191
Domain	E1_FCCH	UBA1 UBA7 UBA6	4.68e-07	3	146	3	PF16190
Domain	UBQ-activ_enz_E1	UBA1 UBA7 UBA6	4.68e-07	3	146	3	IPR018075
Domain	UBA_e1_C	UBA1 UBA7 UBA6	4.68e-07	3	146	3	SM00985
Domain	Ub-activating_enz_E1_C	UBA1 UBA7 UBA6	4.68e-07	3	146	3	IPR018965
Domain	E1_4HB	UBA1 UBA7 UBA6	4.68e-07	3	146	3	IPR032420
Domain	E1_FCCH	UBA1 UBA7 UBA6	4.68e-07	3	146	3	IPR032418
Domain	E1_UFD	UBA1 UBA7 UBA6	4.68e-07	3	146	3	PF09358
Domain	-	UBA1 UBA7 UBA6	1.86e-06	4	146	3	1.10.3240.10
Domain	UBIQUITIN_ACTIVAT_1	UBA1 UBA7 UBA6	4.63e-06	5	146	3	PS00536
Domain	UBA_E1_Cys	UBA1 UBA7 UBA6	4.63e-06	5	146	3	IPR019572
Domain	UBIQUITIN_ACTIVAT_2	UBA1 UBA7 UBA6	4.63e-06	5	146	3	PS00865
Domain	UBA_e1_thiolCys	UBA1 UBA7 UBA6	4.63e-06	5	146	3	PF10585
Domain	UBQ/SUMO-activ_enz_E1-like	UBA1 UBA7 UBA6	9.20e-06	6	146	3	IPR000011
Domain	ThiF_NAD_FAD-bd	UBA1 UBA7 UBA6	5.39e-05	10	146	3	IPR000594
Domain	ThiF	UBA1 UBA7 UBA6	5.39e-05	10	146	3	PF00899
Domain	Furin_repeat	FRAS1 ERBB3 ERBB4	3.50e-04	18	146	3	IPR006212
Domain	FU	FRAS1 ERBB3 ERBB4	3.50e-04	18	146	3	SM00261
Domain	UBQ-activ_enz_E1_CS	UBA1 UBA7	3.60e-04	4	146	2	IPR018074
Domain	UBQ-activ_enz_E1_Cys_AS	UBA1 UBA7	3.60e-04	4	146	2	IPR033127
Domain	Tyr_kinase_EGF/ERB/XmrK_rcpt	ERBB3 ERBB4	3.60e-04	4	146	2	IPR016245
Domain	HEMATOPO_REC_L_F3	IL11RA CNTFR	5.98e-04	5	146	2	PS01354
Domain	Hematopoietin_rcpt_L_F3_CS	IL11RA CNTFR	5.98e-04	5	146	2	IPR003530
Domain	OSR1_C	WNK1 WNK2	8.92e-04	6	146	2	PF12202
Domain	GF_recep_IV	ERBB3 ERBB4	8.92e-04	6	146	2	PF14843
Domain	GF_recep_IV	ERBB3 ERBB4	8.92e-04	6	146	2	IPR032778
Domain	Mg_trans_NIPA	NIPAL1 NIPA2	8.92e-04	6	146	2	IPR008521
Domain	Mg_trans_NIPA	NIPAL1 NIPA2	8.92e-04	6	146	2	PF05653
Domain	Kinase_OSR1/WNK_CCT	WNK1 WNK2	8.92e-04	6	146	2	IPR024678
Domain	DHHC	ZDHHC5 ZDHHC8 KMT2C	9.49e-04	25	146	3	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC5 ZDHHC8 KMT2C	9.49e-04	25	146	3	IPR001594
Domain	FN3	IL11RA OBSCN PTPRZ1 LRFN5 ATF7IP HCFC1 CNTFR	9.77e-04	199	146	7	PS50853
Domain	Recep_L_domain	ERBB3 ERBB4	1.24e-03	7	146	2	PF01030
Domain	ApoL	APOLD1 APOL3	1.24e-03	7	146	2	PF05461
Domain	Furin-like	ERBB3 ERBB4	1.24e-03	7	146	2	PF00757
Domain	Rcpt_L-dom	ERBB3 ERBB4	1.24e-03	7	146	2	IPR000494
Domain	ApoL	APOLD1 APOL3	1.24e-03	7	146	2	IPR008405
Domain	Furin-like_Cys-rich_dom	ERBB3 ERBB4	1.24e-03	7	146	2	IPR006211
Domain	-	ERBB3 ERBB4	1.24e-03	7	146	2	3.80.20.20
Domain	FN3_dom	IL11RA OBSCN PTPRZ1 LRFN5 ATF7IP HCFC1 CNTFR	1.30e-03	209	146	7	IPR003961
Domain	Helicase/UvrB_N	RTEL1 FANCM	1.65e-03	8	146	2	IPR006935
Domain	ResIII	RTEL1 FANCM	1.65e-03	8	146	2	PF04851
Domain	CTLH	RMND5B WDR47	2.11e-03	9	146	2	SM00668
Domain	CTLH_C	RMND5B WDR47	2.62e-03	10	146	2	IPR006595
Domain	CTLH	RMND5B WDR47	2.62e-03	10	146	2	PS50897
Domain	LRR_TYP	LRRTM3 LGI4 LRFN5 SLIT3 SLITRK5 SCRIB	2.70e-03	177	146	6	SM00369
Domain	Leu-rich_rpt_typical-subtyp	LRRTM3 LGI4 LRFN5 SLIT3 SLITRK5 SCRIB	2.70e-03	177	146	6	IPR003591
Domain	LAM_G_DOMAIN	EYS SLIT3 CRB2	3.23e-03	38	146	3	PS50025
Domain	Laminin_G_2	EYS SLIT3 CRB2	3.74e-03	40	146	3	PF02210
Domain	L_dom-like	ERBB3 ERBB4 LRRTM3 LGI4 LRFN5 SLIT3 SLITRK5 SCRIB	4.32e-03	328	146	8	IPR032675
Domain	SSD	PTCHD4 DISP2	4.47e-03	13	146	2	IPR000731
Domain	SSD	PTCHD4 DISP2	4.47e-03	13	146	2	PS50156
Domain	LamG	EYS SLIT3 CRB2	4.90e-03	44	146	3	SM00282
Domain	LRR	LRRTM3 LGI4 LRFN5 SLIT3 SLITRK5 SCRIB	5.03e-03	201	146	6	PS51450
Domain	ARM-type_fold	COPB1 IFT172 LYST FMNL3 SF3B1 ARVCF ANKAR SYMPK	5.25e-03	339	146	8	IPR016024
Domain	Cys-rich_flank_reg_C	LGI4 LRFN5 SLIT3 SLITRK5	5.44e-03	90	146	4	IPR000483
Domain	LRRCT	LGI4 LRFN5 SLIT3 SLITRK5	5.44e-03	90	146	4	SM00082
Domain	-	IL11RA HLA-DRB4 OBSCN CEACAM6 PIGR PTPRZ1 LRFN5 ATF7IP CTLA4 HCFC1 PLXNA2 CNTFR	5.90e-03	663	146	12	2.60.40.10
Domain	-	EYS SLIT3 PAPPA CRB2	6.58e-03	95	146	4	2.60.120.200
Domain	LRRNT	LRRTM3 LRFN5 SLIT3 SLITRK5	7.34e-03	98	146	4	IPR000372
Domain	LRRNT	LRRTM3 LRFN5 SLIT3 SLITRK5	7.34e-03	98	146	4	SM00013
Domain	LRR_1	LRRTM3 LGI4 LRFN5 SLIT3 SLITRK5 SCRIB	7.56e-03	219	146	6	PF00560
Domain	Growth_fac_rcpt_	FRAS1 ERBB3 ERBB4 EYS SLIT3	7.66e-03	156	146	5	IPR009030
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	MBTPS1 FRAS1 IFT172 VPS8 GON4L CEP192 WDR47 YEATS2 PER2 UBR5 PRRC2C DISP2 MTCL1 SCRIB PLXNA2 PDZD2	3.36e-11	407	151	16	12693553
Pubmed	Systematic protein-protein interaction mapping for clinically relevant human GPCRs.	GPAA1 ACO2 SLC39A4 DHRS1 MFSD2A ATP2C1 PTPRA TM9SF2 SLC41A3 SLC5A6 GHITM SLC9A7 NIPA2 SCRIB SETD3 SAP130 MFSD10	1.13e-08	697	151	17	28298427
Pubmed	Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.	ERBB3 ERBB4 PTPRA PIGR SLITRK5 GPR119	5.47e-06	101	151	6	23382219
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 PIEZO1 OBSCN ZDHHC5 CEP192 WNK1 ZDHHC8 LYST KMT2C TKFC PER2 ARVCF CSAD DISP2 HCFC1 WNK2 SYMPK	6.78e-06	1105	151	17	35748872
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MBTPS1 HIF1A RTEL1 SIGMAR1 OBSCN CEP192 NDUFB5 YEATS2 KMT2C LRPPRC ATP2C1 BRI3BP SLC41A3 ANKAR UBA6 SLC9A7 PNPLA7 SAP130 WNK2 PDZD2	7.52e-06	1489	151	20	28611215
Pubmed	In situ hybridization reveals developmental regulation of ErbB1-4 mRNA expression in mouse midbrain: implication of ErbB receptors for dopaminergic neurons.	ERBB3 ERBB4 ENO2	9.41e-06	10	151	3	19298847
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	CACNA1E ERBB4 SLC25A18 SLC2A14 LRRTM3 DHRS1 ZDHHC8 SLC1A2 PTPRA ARVCF	1.20e-05	405	151	10	38187761
Pubmed	Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland.	ERBB4 HIF1A	1.87e-05	2	151	2	24966332
Pubmed	Serum CA125 and NSE: biomarkers of disease severity in patients with silicosis.	MUC16 ENO2	1.87e-05	2	151	2	24642341
Pubmed	Quantitative Phosphoproteomics Analysis of ERBB3/ERBB4 Signaling.	ERBB3 ERBB4	1.87e-05	2	151	2	26745281
Pubmed	Identification and characteristics of a novel E1 like gene nUBE1L in human testis.	UBA1 UBA6	1.87e-05	2	151	2	15202508
Pubmed	UBR5 is a novel regulator of WNK1 stability.	WNK1 UBR5	1.87e-05	2	151	2	35442829
Pubmed	The Escherichia coli adherence factor plasmid of enteropathogenic Escherichia coli causes a global decrease in ubiquitylated host cell proteins by decreasing ubiquitin E1 enzyme expression through host aspartyl proteases.	UBA1 UBA6	1.87e-05	2	151	2	22999844
Pubmed	The upgraded role of HER3 and HER4 receptors in breast cancer.	ERBB3 ERBB4	1.87e-05	2	151	2	19481955
Pubmed	Prognostic significance of serum ERBB3 and ERBB4 mRNA in lung adenocarcinoma patients.	ERBB3 ERBB4	1.87e-05	2	151	2	26254096
Pubmed	Ankyrin-G palmitoylation and βII-spectrin binding to phosphoinositide lipids drive lateral membrane assembly.	ZDHHC5 ZDHHC8	1.87e-05	2	151	2	25049274
Pubmed	The prognostic values of CA125, CA19.9, NSE, AND SCC for stage I NSCLC are limited.	MUC16 ENO2	1.87e-05	2	151	2	22674301
Pubmed	Ubiquitination-activating enzymes UBE1 and UBA6 regulate ubiquitination and expression of cardiac sodium channel Nav1.5.	UBA1 UBA6	1.87e-05	2	151	2	32315024
Pubmed	[Expression and significance of ErbB3 and ErbB4 in patients with laryngeal squamous cell carcinomas].	ERBB3 ERBB4	1.87e-05	2	151	2	17969526
Pubmed	Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease.	HIF1A CTLA4	1.87e-05	2	151	2	37827154
Pubmed	Interactions of HLA-DRB4 and CTLA-4 genes influence thyroid function in Hashimoto's thyroiditis in Japanese population.	HLA-DRB4 CTLA4	1.87e-05	2	151	2	15055474
Pubmed	WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia.	WNK1 WNK2	1.87e-05	2	151	2	35849656
Pubmed	Interaction with ErbB4 promotes hypoxia-inducible factor-1α signaling.	ERBB4 HIF1A	1.87e-05	2	151	2	22308027
Pubmed	Cytogenetic analysis of HER1/EGFR, HER2, HER3 and HER4 in 278 breast cancer patients.	ERBB3 ERBB4	1.87e-05	2	151	2	18182100
Pubmed	Muscle stem cell fate is controlled by the cell-polarity protein Scrib.	PAX7 SCRIB	1.87e-05	2	151	2	25704816
Pubmed	YEATS2 is a target of HIF1α and promotes pancreatic cancer cell proliferation and migration.	HIF1A YEATS2	1.87e-05	2	151	2	32749678
Pubmed	HER3, but Not HER4, Plays an Essential Role in the Clinicopathology and Prognosis of Gastric Cancer: A Meta-Analysis.	ERBB3 ERBB4	1.87e-05	2	151	2	27536774
Pubmed	Protein tyrosine-phosphatase expression profiling in gastric cancer tissues.	PTPRA PTPRZ1	1.87e-05	2	151	2	16338072
Pubmed	The single N-glycan deletion mutant of soluble ErbB3 protein attenuates heregulin β1-induced tumor progression by blocking of the HIF-1 and Nrf2 pathway.	ERBB3 HIF1A	1.87e-05	2	151	2	25451255
Pubmed	Adaptation to HIF1α Deletion in Hypoxic Cancer Cells by Upregulation of GLUT14 and Creatine Metabolism.	HIF1A SLC2A14	1.87e-05	2	151	2	30885992
Pubmed	HER3 and HER4 are highly expressed in human meningiomas.	ERBB3 ERBB4	1.87e-05	2	151	2	31400925
Pubmed	4-Phenybutyric acid promotes gastric cancer cell migration via histone deacetylase inhibition-mediated HER3/HER4 up-regulation.	ERBB3 ERBB4	1.87e-05	2	151	2	28851073
Pubmed	ErbB family immunohistochemical expression in colorectal cancer patients with higher risk of recurrence after radical surgery.	ERBB3 ERBB4	1.87e-05	2	151	2	19390858
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E SLC1A2 WDR47 LRPPRC UBA1 SF3B1 KCNA4 ARVCF UBR5 PRRC2C ATF7IP UBA6 MTCL1 SCRIB WNK2	2.11e-05	963	151	15	28671696
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	ACO2 CAMLG YEATS2 KMT2C TKFC TM9SF2 PRRC2C GHITM SAP130 ALDH7A1	3.35e-05	457	151	10	32344865
Pubmed	Regulation of ubiquitin-proteasome system-mediated Tip110 protein degradation by USP15.	HIF1A LRPPRC SF3B1	4.31e-05	16	151	3	24984263
Pubmed	Prognostic value of tumor markers, NSE, CA125 and SCC, in operable NSCLC Patients.	MUC16 ENO2	5.60e-05	3	151	2	23712355
Pubmed	Expression of ErbB3, ErbB4, and neuregulin-1 mRNA during tooth development.	ERBB3 ERBB4	5.60e-05	3	151	2	12112465
Pubmed	Specificity of the E1-E2-E3 enzymatic cascade for ubiquitin C-terminal sequences identified by phage display.	UBA1 UBA6	5.60e-05	3	151	2	23003343
Pubmed	Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer.	HIF1A PIEZO1	5.60e-05	3	151	2	35993548
Pubmed	Glutamate transporter GLT-1 is transiently localized on growing axons of the mouse spinal cord before establishing astrocytic expression.	SLC1A2 ENO2	5.60e-05	3	151	2	9671661
Pubmed	ErbB receptor signaling directly controls oligodendrocyte progenitor cell transformation and spontaneous remyelination after spinal cord injury.	ERBB3 ERBB4	5.60e-05	3	151	2	30637799
Pubmed	The mechanosensitive ion channel PIEZO1 promotes satellite cell function in muscle regeneration.	PIEZO1 PAX7	5.60e-05	3	151	2	36446523
Pubmed	erbB genes in the mouse uterus: cell-specific signaling by epidermal growth factor (EGF) family of growth factors during implantation.	ERBB3 ERBB4	5.60e-05	3	151	2	9851845
Pubmed	Differential Expression of MUC12, MUC16, and MUC20 in Patients with Active and Remission Ulcerative Colitis.	MUC16 MUC12	5.60e-05	3	151	2	26770020
Pubmed	Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy.	SLC14A2 ARMH4	5.60e-05	3	151	2	26927669
Pubmed	Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling.	WNK1 WNK2	5.60e-05	3	151	2	23797875
Pubmed	Signaling pathway of ciliary neurotrophic factor in neuroblastoma cell lines.	LRPPRC CNTFR	5.60e-05	3	151	2	11464862
Pubmed	The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.	ERBB3 ERBB4	5.60e-05	3	151	2	28304405
Pubmed	Expression and significance of HER family receptors in neuroblastic tumors.	ERBB3 ERBB4	5.60e-05	3	151	2	21203803
Pubmed	Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking.	ZDHHC5 ZDHHC8	5.60e-05	3	151	2	22325201
Pubmed	Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes.	ZDHHC5 ZDHHC8	5.60e-05	3	151	2	19801377
Pubmed	High incidence of ErbB3, ErbB4, and MET expression in ovarian cancer.	ERBB3 ERBB4	5.60e-05	3	151	2	24901400
Pubmed	The CREB1/WNK1 axis promotes the tumorigenesis of ovarian cancer via regulating HIF-1.	HIF1A WNK1	5.60e-05	3	151	2	38599542
Pubmed	Specific antibodies and sensitive immunoassays for the human epidermal growth factor receptors (HER2, HER3, and HER4).	ERBB3 ERBB4	5.60e-05	3	151	2	28653892
Pubmed	Preliminary investigation of gene expression levels of PAPP-A, STC-2, and HIF-1α in SARS-Cov-2 infected patients.	HIF1A PAPPA	5.60e-05	3	151	2	35796937
Pubmed	Uncommon somatic mutations in metastatic NUT midline carcinoma.	KMT2C SF3B1	5.60e-05	3	151	2	28967088
Pubmed	An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels.	ERBB3 ERBB4	5.60e-05	3	151	2	11867753
Pubmed	Dynamically varying interactions between heregulin and ErbB proteins detected by single-molecule analysis in living cells.	ERBB3 ERBB4	5.60e-05	3	151	2	22891299
Pubmed	Characterization of a breast cancer cell differentiation factor that specifically activates the HER4/p180erbB4 receptor.	ERBB3 ERBB4	5.60e-05	3	151	2	7689552
Pubmed	ErbB receptor tyrosine kinase family expression levels in urothelial bladder carcinoma.	ERBB3 ERBB4	5.60e-05	3	151	2	23333248
Pubmed	Expression and potential role of ErbB receptors in type II endometrial cancer.	ERBB3 ERBB4	5.60e-05	3	151	2	23395558
Pubmed	A novel model for extrapleural cavity metastasis assessment in patients with lung cancer.	MUC16 ENO2	5.60e-05	3	151	2	33709781
Pubmed	[Down-regulation of VEGF expression and up-regulation of PEDF expression in human corneal epithelial cells under hypoxic condition by RNA interference of HIF-1α].	HIF1A SERPINF1	5.60e-05	3	151	2	30554580
Pubmed	Associations of rs2300782 CAMK4, rs2292239 ERBB3 and rs10491034 ARHGAP22 with Diabetic Retinopathy Among Chinese Hui Population.	ERBB3 ARHGAP22	5.60e-05	3	151	2	31976761
Pubmed	Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3.	ERBB3 ERBB4	5.60e-05	3	151	2	9516479
Pubmed	Binding interaction of the heregulinbeta egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis.	ERBB3 ERBB4	5.60e-05	3	151	2	9565587
Pubmed	GREM1, LRPPRC and SLC39A4 as potential biomarkers of intervertebral disc degeneration: a bioinformatics analysis based on multiple microarray and single-cell sequencing data.	SLC39A4 LRPPRC	5.60e-05	3	151	2	37700277
Pubmed	Evaluation of type 1 growth factor receptor family expression in benign and malignant thyroid lesions.	ERBB3 ERBB4	5.60e-05	3	151	2	18424286
Pubmed	Protein expression of HER2, 3, 4 in gastric cancer: correlation with clinical features and survival.	ERBB3 ERBB4	5.60e-05	3	151	2	25731189
Pubmed	Functional characterization of NIPA2, a selective Mg2+ transporter.	NIPAL1 NIPA2	5.60e-05	3	151	2	18667602
Pubmed	GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40).	FFAR1 GPR119	5.60e-05	3	151	2	27779915
Pubmed	Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	OBSCN GON4L CEP192 MAGEE1 FANCM	8.18e-05	101	151	5	10997877
Pubmed	Motor neurons control blood vessel patterning in the developing spinal cord.	HIF1A PAX7 ENO2	1.01e-04	21	151	3	28262664
Pubmed	The relation between survival and expression of HER1 and HER2 depends on the expression of HER3 and HER4: a study in bladder cancer patients.	ERBB3 ERBB4	1.12e-04	4	151	2	16685269
Pubmed	Characterisation of HER heterodimers in breast cancer using in situ proximity ligation assay.	ERBB3 ERBB4	1.12e-04	4	151	2	24557338
Pubmed	Inverse regulation of EGFR/HER1 and HER2-4 in normal and malignant human breast tissue.	ERBB3 ERBB4	1.12e-04	4	151	2	23991224
Pubmed	Neuregulin signaling regulates neural precursor growth and the generation of oligodendrocytes in vitro.	ERBB3 ERBB4	1.12e-04	4	151	2	11425901
Pubmed	[Neuregulin-1 promotes proliferation and migration of human coronary artery smooth muscle cells by enhancing its receptor phosphorylation].	ERBB3 ERBB4	1.12e-04	4	151	2	26648299
Pubmed	Expression of heregulin, phosphorylated HER-2, HER-3 and HER-4 in HER-2 negative breast cancers.	ERBB3 ERBB4	1.12e-04	4	151	2	19148499
Pubmed	Expression of epidermal growth factors, erbBs, in the nasal mucosa of patients with chronic hypertrophic rhinitis.	ERBB3 ERBB4	1.12e-04	4	151	2	22327010
Pubmed	WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.	WNK1 WNK2	1.12e-04	4	151	2	11571656
Pubmed	Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.	ERBB3 ERBB4	1.12e-04	4	151	2	17177598
Pubmed	Human hypertension caused by mutations in WNK kinases.	WNK1 WNK2	1.12e-04	4	151	2	11498583
Pubmed	HER2 phosphorylation is maintained by a PKB negative feedback loop in response to anti-HER2 herceptin in breast cancer.	ERBB3 ERBB4	1.12e-04	4	151	2	21203579
Pubmed	Hypoxia regulation of facilitated glucose transporter-1 and glucose transporter-3 in mouse chondrocytes mediated by HIF-1alpha.	HIF1A SLC2A14	1.12e-04	4	151	2	17983831
Pubmed	Per1/Per2-Igf2 axis-mediated circadian regulation of myogenic differentiation.	PER2 PAX7	1.12e-04	4	151	2	34009269
Pubmed	Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.	ERBB4 PTPRZ1	1.12e-04	4	151	2	17579610
Pubmed	Clinical evaluation and therapeutic monitoring value of serum tumor markers in lung cancer.	MUC16 ENO2	1.12e-04	4	151	2	26560853
Pubmed	Analysis of ErbB receptors in pulmonary carcinoid tumors.	ERBB3 ERBB4	1.12e-04	4	151	2	19447869
Pubmed	Evaluation of the prognostic and predictive value of HER family mRNA expression in high-risk early breast cancer: a Hellenic Cooperative Oncology Group (HeCOG) study.	ERBB3 ERBB4	1.12e-04	4	151	2	18985033
Pubmed	Association of type 1 diabetes with two Loci on 12q13 and 16p13 and the influence coexisting thyroid autoimmunity in Japanese.	ERBB3 CTLA4	1.12e-04	4	151	2	18940880
Pubmed	Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.	WNK1 WNK2	1.12e-04	4	151	2	34384519
Pubmed	Orthogonal ubiquitin transfer identifies ubiquitination substrates under differential control by the two ubiquitin activating enzymes.	UBA1 UBA6	1.12e-04	4	151	2	28134249
Pubmed	Activated HER-receptors in predicting outcome of ER-positive breast cancer patients treated with adjuvant endocrine therapy.	ERBB3 ERBB4	1.12e-04	4	151	2	22854050
Pubmed	The erbB/HER type 1 tyrosine kinase receptor family.	ERBB3 ERBB4	1.12e-04	4	151	2	9771475
Pubmed	IRS4, a novel modulator of BMP/Smad and Akt signalling during early muscle differentiation.	IRS4 PAX7	1.12e-04	4	151	2	28821740
Pubmed	Expression of the HER-1-4 family of receptor tyrosine kinases in neuroendocrine tumours.	ERBB3 ERBB4	1.12e-04	4	151	2	20204273
Pubmed	HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease.	HIF1A SF3B1	1.12e-04	4	151	2	26083752
Pubmed	Laminin-1 and epidermal growth factor family members co-stimulate fetal pancreas cell proliferation and colony formation.	ERBB3 ERBB4	1.12e-04	4	151	2	15733067
Interaction	YIPF3 interactions	GPAA1 SIGMAR1 FFAR1 PIEZO1 P2RY8 NDUFB5 SLC7A2 BRI3BP SLC5A6 NIPAL1 NIPA2	1.14e-07	186	146	11	int:YIPF3
GeneFamily	Solute carriers	SLC25A18 SLC2A14 SLC39A4 SLC12A8 SLC1A2 SLC22A6 SLC7A2 SLC41A3 SLC5A6 SLC9A7 SLC25A44 SLC14A2	1.20e-06	395	96	12	752
GeneFamily	Ubiquitin like modifier activating enzymes	UBA1 UBA7 UBA6	1.69e-05	10	96	3	100
GeneFamily	Erb-b2 receptor tyrosine kinases	ERBB3 ERBB4	1.66e-04	4	96	2	1096
GeneFamily	Fibronectin type III domain containing	OBSCN PTPRZ1 LRFN5 ATF7IP CNTFR	1.63e-03	160	96	5	555
GeneFamily	ATAC complex	YEATS2 HCFC1	2.09e-03	13	96	2	1058
Coexpression	GSE38696_LIGHT_ZONE_VS_DARK_ZONE_BCELL_DN	NPR2 PIEZO1 OBSCN WNK1 DHRS1 SLC1A2 PIGZ SIAH3 SLC41A3 PAPPA	6.94e-09	139	148	10	M9006
Coexpression	ANDERSON_BLOOD_CN54GP140_ADJUVANTED_WITH_GLA_AF_AGE_18_45YO_1DY_DN	ACO2 VPS8 UBA1 PRRC2C SAP130 MAST3	8.87e-06	85	148	6	M41085
Coexpression	GSE24102_GRANULOCYSTIC_MDSC_VS_NEUTROPHIL_UP	NPR2 FANCM TM6SF1 DHRS1 HSPB6 NIPA2 SAP130 MFSD10	1.89e-05	200	148	8	M4541
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1E ERBB3 ERBB4 MUC16 SLC12A8 PIGR SLIT3 PNPLA7 WNK2	2.58e-08	200	149	9	c450a15e21fa72d071ed6e3b9f22de557a0f3cea
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B SERPINF1 CEACAM6 PIGR ARVCF PTPRZ1 PNPLA7 WNK2	9.28e-08	166	149	8	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B SERPINF1 CEACAM6 PIGR ARVCF PTPRZ1 PNPLA7 WNK2	9.28e-08	166	149	8	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KIF26B SERPINF1 CEACAM6 PIGR ARVCF PTPRZ1 PNPLA7 WNK2	9.28e-08	166	149	8	4586d6725403f879fc96f67be579022587ce1906
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 KIF26B SERPINF1 LRRTM3 SLC7A2 LRFN5 SLIT3 PAPPA	3.06e-07	194	149	8	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 CEACAM6 PIGR SLITRK5 NIPAL1 DMBT1 WNK2	3.18e-07	195	149	8	fc2a1d84b3d013e5cb9e7b9cdd740e4010897d20
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIF1A COPB1 ACO2 WNK1 SF3B1 TM9SF2 PRRC2C PCDHGC3	3.31e-07	196	149	8	151f1a29a91f8b234e9b6ed062666357a2f69128
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 CEACAM6 SERPINA11 PIGR SLITRK5 DMBT1 WNK2	3.44e-07	197	149	8	e2c820c4e4a6cd01ceb020473286e3f5d4e3718e
ToppCell	Bronchial-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Mucous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 CEACAM6 SERPINA11 PIGR SLITRK5 PNPLA7 WNK2	3.72e-07	199	149	8	eb2d1b7e875c5bf833e7a80b43282e12893c34e9
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CACNA1E MUC16 SLC12A8 PER2 PIGR PTPRZ1 SLITRK5 WNK2	3.86e-07	200	149	8	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 SERPINF1 OBSCN PCDHA2 HSPB6 PCDHGC3 PDZD2	1.37e-06	164	149	7	a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCell	Adult-Epithelial-lung_goblet_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 MUC16 LRRTM3 PIGR PTPRZ1 UGT2A1 WNK2	2.03e-06	174	149	7	7d2f802f493f19a068e097b2909a9000e2160266
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 FRAS1 MUC16 LGI4 ARHGAP22 CRB2 ARMH4	2.63e-06	181	149	7	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 FRAS1 MUC16 LGI4 ARHGAP22 CRB2 ARMH4	2.63e-06	181	149	7	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 KIF26B CCDC175 MFSD2A LRFN5 SLIT3 CRB2	2.63e-06	181	149	7	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 ERBB4 CSMD2 LGI4 KCNA4 PTPRZ1	2.63e-06	181	149	7	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	BNC2 KIF26B CCDC175 MFSD2A LRFN5 SLIT3 CRB2	2.63e-06	181	149	7	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ERBB4 CSMD2 LGI4 KCNA4 PTPRZ1 SLC9A7	2.73e-06	182	149	7	b4fc5e4f5d8440a3c9ee0a6fd0da87b43cabc8c6
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 ERBB4 CSMD2 LGI4 KCNA4 PTPRZ1	3.04e-06	185	149	7	56c7a0dbf141728ac76b8c90af197719942ca67c
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KIF26B PTCHD4 SIAH3 EYS PTPRZ1 PAPPA	3.27e-06	187	149	7	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CACNA1E KIF26B PAPPA DISP2 ACKR1 ENO2 SYT13	3.38e-06	188	149	7	b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCell	droplet-Heart-nan-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTEL1 MFSD2A ARVCF SLC25A44 PAPPA SCRIB ACKR1	3.50e-06	189	149	7	0493f7b79127c207fd7ade778ef4810500495d7e
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 MUC16 CEACAM6 IFI27 PIGR UGT2A1 PAX7	3.63e-06	190	149	7	6ea9fa08bd97bedcb21d3654467e7f8dd74c8fd0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERBB3 LRRTM3 SLC1A2 KCNA4 PTPRZ1 PCDHGC3 PDZD2	3.63e-06	190	149	7	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KIF26B PTCHD4 SIAH3 EYS PTPRZ1 PAPPA	3.63e-06	190	149	7	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	COVID-19-Epithelial_cells-Airway_goblet\|COVID-19 / group, cell type (main and fine annotations)	ERBB3 ERBB4 MUC16 CEACAM6 PIGR PTPRZ1 WNK2	3.63e-06	190	149	7	51ca9ef4df3220487152fcf684147730637c7cc1
ToppCell	COVID-19_Severe-Neu_3\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	PRR23A PCDHA2 CSMD2 LRFN5 UGT2A1 SYT13	3.68e-06	123	149	6	4c20c025b6f19f075a13282288fc537e6e186217
ToppCell	COVID-19_Severe-Neu_3\|World / 5 Neutrophil clusters in COVID-19 patients	PRR23A FRAS1 PCDHA2 LRFN5 UGT2A1 SYT13	3.86e-06	124	149	6	54b42ffb161eece4ae308782e43a0e0dc360281e
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 SERPINF1 MUC16 CEACAM6 PIGR UGT2A1 WNK2	4.30e-06	195	149	7	2a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 SERPINF1 MUC16 CEACAM6 PIGR UGT2A1 WNK2	4.30e-06	195	149	7	576142b4e75457c0973051bccc4163bd624496af
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ERBB3 SERPINF1 MUC16 CEACAM6 PIGR UGT2A1 WNK2	4.30e-06	195	149	7	8f151066ad3ebd9661ea0b733f03c2ce1518f9ad
ToppCell	Epithelial_cells-Club_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ERBB3 SERPINF1 MUC16 CEACAM6 PIGR PTPRZ1 WNK2	4.30e-06	195	149	7	b758676abfc4e6930b696d270ecc0ea461b87a54
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|COVID-19 / Condition, Lineage and Cell class	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.45e-06	196	149	7	dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.45e-06	196	149	7	a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERBB3 ERBB4 LRRTM3 SLC1A2 KCNA4 PTPRZ1 PDZD2	4.45e-06	196	149	7	f374cb3ec31c6eef2cef9e07547bfd1e380553af
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL11RA BNC2 SERPINF1 HSPB6 SLIT3 PAPPA CRB2	4.45e-06	196	149	7	46d665de09f8164690b9a3e0acf0b0afa3f81b3d
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERBB3 ERBB4 LRRTM3 SLC1A2 KCNA4 PTPRZ1 PDZD2	4.45e-06	196	149	7	671c380b58d7f634b4fbec38c357d357ea4f3535
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.45e-06	196	149	7	91a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.45e-06	196	149	7	e819088a74d29e958371aa851ac9c74ec55367b7
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.45e-06	196	149	7	e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCell	Mild_COVID-19-Epithelial-Basal/Club\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.60e-06	197	149	7	4cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IL11RA BNC2 IL17RC CSMD2 KCNA4 SLIT3 CRB2	4.76e-06	198	149	7	0cd930e374c2c48d1991b51c025f9801b22ecee7
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 CEACAM6 PIGR UGT2A1 SLITRK5 WNK2	4.76e-06	198	149	7	5dd2aa7684c36beffa204ca4c04d0501cabac10f
ToppCell	Parenchymal-10x3prime_v2-Stromal-Mesofibroblastic-Mesothelia\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	IL11RA BNC2 IL17RC CSMD2 KCNA4 SLIT3 CRB2	4.76e-06	198	149	7	e0df6d6ff2a9c41d813f84a2a5ee7cb5f6fc3e30
ToppCell	distal-1-mesenchymal-Mesothelial\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	BNC2 FRAS1 MUC16 SLC12A8 KCNA4 PAPPA CRB2	4.92e-06	199	149	7	8dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.92e-06	199	149	7	70c0b9cff195d3d24e98443a729e211cac20c90f
ToppCell	Biopsy_Other_PF-Epithelial-MUC5B+\|Biopsy_Other_PF / Sample group, Lineage and Cell type	ERBB3 SERPINF1 MUC16 CEACAM6 PIGR PTPRZ1 WNK2	4.92e-06	199	149	7	afd0df242a93f176438309668a9487be1250d9ca
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.92e-06	199	149	7	ec1e110671e7725f752163c7241dbbf638dec2b2
ToppCell	distal-Epithelial-Mucous-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	ERBB3 SERPINF1 CEACAM6 SERPINA11 PIGR PTPRZ1 WNK2	4.92e-06	199	149	7	35fb7bd35e53d8ca189fe8c7744211a5201081f6
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_secretory\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SERPINF1 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	4.92e-06	199	149	7	a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCell	Neuronal-Inhibitory-iB-iB_2(PVALB)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	ERBB4 KIF26B PTCHD4 SIAH3 EYS PTPRZ1 PAPPA	5.08e-06	200	149	7	1276bfa911fddada4235e12e3081baa53164574b
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SLC12A8 SLC1A2 PER2 PIGR PTPRZ1 DMBT1 WNK2	5.08e-06	200	149	7	030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 ERBB3 ERBB4 LGI4 MFSD2A PTPRZ1 SLC9A7	5.08e-06	200	149	7	de55100e98d3e9b8a74e37aebcd3afa2b0996527
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Club\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	5.08e-06	200	149	7	85f946dd3831acf3488c87efba96689cc2667c3a
ToppCell	Biopsy_IPF-Epithelial-MUC5B+\|Biopsy_IPF / Sample group, Lineage and Cell type	ERBB3 SERPINF1 MUC16 CEACAM6 PIGR PTPRZ1 WNK2	5.08e-06	200	149	7	f0a6747f6d37ec6d261bd649ac678c39cca5e4c8
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Club-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	5.08e-06	200	149	7	8a44a4f7ea9358f2194a490e79601c98ff7fdcb0
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Club\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 UGT2A1 WNK2	5.08e-06	200	149	7	30d428510c68da96c7c8cfd472f449ebb9631132
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_1\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	GABRG3 AKAP14 TM6SF1 SIAH3 SYT13 MAST3	8.09e-06	141	149	6	73b3e967357cba7585d97ec9e9d48d3e94ebe31e
ToppCell	Basal_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FRAS1 SERPINF1 PTCHD4 PTPRZ1 SLITRK5 ALDH7A1	1.24e-05	152	149	6	72499e4d2b374ef5f1621c89d94727ecf4bd4d5d
ToppCell	Children_(3_yrs)-Epithelial-basal_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 ERBB4 SERPINF1 PTCHD4 PLXNA2 ALDH7A1	1.49e-05	157	149	6	6ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCell	COVID_non-vent-Lymphocytic-Dendritic-pDC\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SERPINF1 SLITRK5 SLC9A7 ACKR1 PCDHGC3 ALDH7A1	1.66e-05	160	149	6	61f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCell	COVID_non-vent-Lymphocytic-Dendritic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SERPINF1 SLITRK5 SLC9A7 ACKR1 PCDHGC3 ALDH7A1	1.66e-05	160	149	6	34b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRTM3 LGI4 PTPRZ1 LRFN5 SLITRK5 CNTFR	1.78e-05	162	149	6	d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRTM3 LGI4 PTPRZ1 LRFN5 SLITRK5 CNTFR	1.78e-05	162	149	6	5bbd7130d4dad9035e73a439dda568195c136f31
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRTM3 LGI4 PTPRZ1 LRFN5 SLITRK5 CNTFR	1.78e-05	162	149	6	eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LRRTM3 LGI4 PTPRZ1 LRFN5 SLITRK5 CNTFR	1.78e-05	162	149	6	e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGR PTPRZ1 NFRKB DMBT1 WNK2	1.85e-05	163	149	6	a1fbefe53523a9879a4d4b493071059798b5f917
ToppCell	5'-Airway_Nasal_SMG-Epithelial\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGR PTPRZ1 NFRKB DMBT1 WNK2	1.85e-05	163	149	6	454a5e87e2f9f66e38cc5aa1b433c47b54c9be42
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGR PTPRZ1 NFRKB DMBT1 WNK2	1.85e-05	163	149	6	d9bd9d90cfa4e85d5ea51f8f3ee14a700571f508
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGR PTPRZ1 NFRKB DMBT1 WNK2	1.85e-05	163	149	6	f6847f47a8856c0d4136c1af317432d45eccfde9
ToppCell	5'-Airway_Nasal_SMG\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGR PTPRZ1 NFRKB DMBT1 WNK2	1.85e-05	163	149	6	d8450bf9c6d2ec5dd1472952c9e65f82f995337a
ToppCell	5'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGR PTPRZ1 NFRKB DMBT1 WNK2	1.85e-05	163	149	6	be6cc44df9a2b10dce1a353717c279c3558f8fec
ToppCell	Club_cells-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	SERPINF1 CEACAM6 SERPINA11 PIGR PTPRZ1 WNK2	2.05e-05	166	149	6	a440aa338aa0c6cd0b5800dfa7e83f8ca16fce1a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	GABRG3 CACNA1E BNC2 CSMD2 EYS PDZD2	2.12e-05	167	149	6	3edb0570e583bb527165bcd8a4c25a042054043b
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 ERBB4 LGI4 KCNA4 PTPRZ1	2.12e-05	167	149	6	49b19159c62d33d65ed1e59a148c11ae902fd41c
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E SERPINF1 CEACAM6 SERPINA11 PIGR WNK2	2.26e-05	169	149	6	db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E SERPINF1 CEACAM6 SERPINA11 PIGR WNK2	2.26e-05	169	149	6	97b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E SERPINF1 CEACAM6 SERPINA11 PIGR WNK2	2.26e-05	169	149	6	1a684471dbda42e1470e5a889648666e14f25982
ToppCell	PCW_05-06-Neuronal-Neuronal_SCP-neuro_proliferating_SCP3_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ERBB3 ERBB4 LGI4 KCNA4 PTPRZ1 SLC9A7	2.26e-05	169	149	6	d9c3b22f62b882b8a2ea6fd9cf7afbe6d1775745
ToppCell	LV-16._Neuronal\|LV / Chamber and Cluster_Paper	ERBB3 LGI4 PTPRZ1 SLITRK5 PAPPA CNTFR	2.26e-05	169	149	6	a8fc8ab0f0757e939e213efb61c03cfe390bf7d2
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ERBB3 MUC16 CEACAM6 PIGR PTPRZ1 WNK2	2.58e-05	173	149	6	d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCell	COVID-19-Heart-Neuronal\|Heart / Disease (COVID-19 only), tissue and cell type	ERBB3 IRS4 LGI4 PTPRZ1 SLITRK5 PAPPA	2.58e-05	173	149	6	6fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 FRAS1 MUC16 PAPPA CRB2 ARMH4	2.58e-05	173	149	6	30d67738633493d47f06ae452424382f069b6c0a
ToppCell	3'-Airway_Nasal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_mucus_secreting_cell-SMG_mucous-SMG_mucous_L.0.6.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CACNA1E PIGZ SERPINA11 PIGR SLITRK5 SYT13	2.67e-05	174	149	6	b1b54e4e23df8cfc04bf298d5c53de203a38b267
ToppCell	Adult-Epithelial-basal_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 SERPINF1 C2orf78 PTPRZ1 PLXNA2 ALDH7A1	2.67e-05	174	149	6	a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KIF26B MUC16 CEACAM6 COG8 PTPRZ1 WNK2	2.67e-05	174	149	6	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BNC2 FRAS1 MUC16 PAPPA CRB2 ARMH4	2.67e-05	174	149	6	a9c6edf5c3fc119c24425f921c5566a8356c30fe
ToppCell	ASK452-Epithelial-Secretory\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	ERBB3 GLRA3 YEATS2 PIGR PTPRZ1 WNK2	2.84e-05	176	149	6	dd334c8a8a31dc26b2d558df0ef6bed6dc1a6610
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 ERBB3 ERBB4 LGI4 PTPRZ1 SLC9A7	2.94e-05	177	149	6	d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell	(5)_Glands_mucous\|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)	MUC16 SERPINA11 PIGR SLITRK5 DMBT1 SYT13	3.03e-05	178	149	6	f0f19b0d78f2cc5df4d4c321a953a6e447d5114a
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 SERPINF1 PTPRZ1 SLITRK5 PLXNA2 ALDH7A1	3.03e-05	178	149	6	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 FFAR1 MDM1 NIPAL1 SLC9A7 SYT13	3.03e-05	178	149	6	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BNC2 ERBB4 KIF26B LRFN5 SLIT3 CRB2	3.03e-05	178	149	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-BEST4+_epithelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERBB3 CEACAM6 PIGR DMBT1 WNK2 CNTFR	3.22e-05	180	149	6	7c7c4d64ff99d0710a7d19d8bc29fc9217394db1
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 MUC16 C2orf78 SLC7A2 MFSD2A CRB2	3.33e-05	181	149	6	65eaa9bc1022bcf0c5f0f92c07a2cbbf11f9b59c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-mesothelial_cell-Mesothelium_(PRG4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FRAS1 MUC16 C2orf78 SLC7A2 MFSD2A CRB2	3.33e-05	181	149	6	eaac7d58117eddfff06b25521efc431c1351d592
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 ERBB3 ERBB4 CSMD2 LGI4 PTPRZ1	3.43e-05	182	149	6	bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERBB3 LGI4 ARVCF PAPPA SCRIB ENO2	3.43e-05	182	149	6	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	Hippocampus-Neuronal-Inhibitory\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ERBB4 TM6SF1 PTCHD4 UBR5 PRRC2C SLC5A6	3.43e-05	182	149	6	b54ae650c04dfd0759c5f5e752b9bf684dd36516
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ERBB4 KIF26B PTCHD4 SIAH3 EYS PAPPA	3.43e-05	182	149	6	a3c5c0eff527c8d3848acda14af8f9e99c69b0de
Disease	Global developmental delay	CACNA1E GPAA1 LGI4 PNPT1 TKFC SLC5A6	5.63e-05	133	147	6	C0557874
Disease	Juvenile amyotrophic lateral sclerosis	SIGMAR1 SPG11	7.37e-05	3	147	2	cv:C3468114
Disease	lung adenocarcinoma (is_implicated_in)	ERBB3 ERBB4 KMT2C UBR5	1.05e-04	49	147	4	DOID:3910 (is_implicated_in)
Disease	Schizophrenia	ERBB3 ERBB4 SIGMAR1 CSMD2 ZDHHC8 SLC1A2 PTPRA ARVCF PTPRZ1 SLIT3 OR4C46 CTLA4 ENO2 PLXNA2	1.40e-04	883	147	14	C0036341
Disease	Juvenile amyotrophic lateral sclerosis	SIGMAR1 SPG11	1.47e-04	4	147	2	C3468114
Disease	stomach carcinoma (is_marker_for)	ERBB3 ERBB4 KMT2C	2.27e-04	24	147	3	DOID:5517 (is_marker_for)
Disease	refractive error	ACO2 SLC1A2 PNPT1 LRPPRC KCNA4 LRFN5 ETNK1 SLC14A2	2.40e-04	326	147	8	MONDO_0004892
Disease	response to platinum based chemotherapy, cytotoxicity measurement	FRAS1 EYS	2.44e-04	5	147	2	EFO_0004647, EFO_0006952
Disease	laryngeal carcinoma (is_marker_for)	KMT2C UBR5	3.65e-04	6	147	2	DOID:2600 (is_marker_for)
Disease	pseudohypoaldosteronism (implicated_via_orthology)	WNK1 WNK2	3.65e-04	6	147	2	DOID:4479 (implicated_via_orthology)
Disease	cortical surface area measurement	BNC2 PRR23A ERBB3 NPR2 COPB1 KIF26B SLC12A8 SIAH3 SF3B1 PRRC2C PAPPA MTCL1 PAX7 SETD3 PLXNA2 WNK2 PDZD2	3.99e-04	1345	147	17	EFO_0010736
Disease	cortical thickness	BNC2 PRR23A ERBB3 NPR2 MDM1 SLC12A8 TM6SF1 SF3B1 MTCL1 PAX7 SETD3 PLXNA2 WNK2 CRB2 PDZD2	4.61e-04	1113	147	15	EFO_0004840
Disease	free cholesterol change measurement, high density lipoprotein cholesterol measurement	TM9SF2 SLIT3	6.77e-04	8	147	2	EFO_0004612, EFO_0020905
Disease	Developmental delay (disorder)	PNPT1 TKFC SLC5A6	8.31e-04	37	147	3	C0424605
Disease	tongue squamous cell carcinoma (is_marker_for)	ERBB3 ERBB4 FANCM	8.31e-04	37	147	3	DOID:0050865 (is_marker_for)
Disease	ductal carcinoma in situ (is_marker_for)	ERBB3 ERBB4 HIF1A	9.71e-04	39	147	3	DOID:0060074 (is_marker_for)
Disease	retinal vasculature measurement	ERBB4 ACO2 MUC12 COG8 EYS KCNA4 SYT13 CRB2 PDZD2	1.18e-03	517	147	9	EFO_0010554
Disease	oral microbiome measurement	FRAS1 KMT2C PDZD2	1.21e-03	42	147	3	EFO_0801229
Disease	hereditary spastic paraplegia (implicated_via_orthology)	NIPAL1 NIPA2 PNPLA7	1.29e-03	43	147	3	DOID:2476 (implicated_via_orthology)
Disease	gallbladder neoplasm	ERBB3 ERBB4	1.32e-03	11	147	2	C0016978
Disease	gastric adenocarcinoma (is_implicated_in)	RTEL1 UBR5	1.32e-03	11	147	2	DOID:3717 (is_implicated_in)
Disease	Malignant neoplasm of gallbladder	ERBB3 ERBB4	1.32e-03	11	147	2	C0153452
Disease	macular retinal edema (is_marker_for)	HIF1A SERPINF1	1.57e-03	12	147	2	DOID:4449 (is_marker_for)
Disease	hemolysis	PIEZO1 EYS KCNA4	1.67e-03	47	147	3	EFO_0009473
Disease	brain measurement, neuroimaging measurement	PRR23A ERBB3 COPB1 KIF26B SLC12A8 APOLD1 PAPPA SETD3 WNK2	1.81e-03	550	147	9	EFO_0004346, EFO_0004464
Disease	homostachydrine measurement	ERBB4 EYS	1.85e-03	13	147	2	EFO_0021164
Disease	Intellectual Disability	CACNA1E GON4L LGI4 SLC1A2 PNPT1 KMT2C MFSD2A SLC5A6	1.86e-03	447	147	8	C3714756
Disease	median neuropathy (biomarker_via_orthology)	ERBB3 ERBB4	2.16e-03	14	147	2	DOID:571 (biomarker_via_orthology)
Disease	thalamus volume change measurement	KIF26B LRFN5	2.16e-03	14	147	2	EFO_0021496
Disease	precuneus cortex volume measurement	PIGR ETNK1	2.16e-03	14	147	2	EFO_0010326
Disease	hypertension (is_marker_for)	HIF1A PAPPA ENO2	2.36e-03	53	147	3	DOID:10763 (is_marker_for)
Disease	Heschl's gyrus morphology measurement	BNC2 VPS8 DISP2	2.36e-03	53	147	3	EFO_0005852
Disease	neuroimaging measurement	PRR23A ERBB3 KIF26B ZDHHC5 SLC12A8 ARHGAP22 APOLD1 PRRC2C PAPPA PAX7 SETD3 PLXNA2 WNK2	2.74e-03	1069	147	13	EFO_0004346
Disease	N-acetyl-beta-alanine measurement	C1QL3 PTPRA	2.83e-03	16	147	2	EFO_0021430
Disease	Amyotrophic Lateral Sclerosis	ERBB4 SIGMAR1 SLC1A2	3.06e-03	58	147	3	C0002736
Disease	Benign neoplasm of stomach	ERBB3 UBR5	3.19e-03	17	147	2	C0153943
Disease	Neoplasm of uncertain or unknown behavior of stomach	ERBB3 UBR5	3.19e-03	17	147	2	C0496905
Disease	Amyotrophic lateral sclerosis	SIGMAR1 SPG11	3.19e-03	17	147	2	cv:C0002736
Disease	Carcinoma in situ of stomach	ERBB3 UBR5	3.19e-03	17	147	2	C0154060
Disease	Malignant neoplasm of skin	ERBB3 ERBB4 HIF1A	3.21e-03	59	147	3	C0007114
Disease	Skin Neoplasms	ERBB3 ERBB4 HIF1A	3.21e-03	59	147	3	C0037286
Disease	chromosomal aberration frequency	COPB1 UBR5	3.58e-03	18	147	2	EFO_0009860
Disease	progression free survival, ovarian carcinoma	FMNL3 ARMH4	3.58e-03	18	147	2	EFO_0001075, EFO_0004920
Disease	squamous cell carcinoma (is_implicated_in)	KMT2C CTLA4	3.58e-03	18	147	2	DOID:1749 (is_implicated_in)
Disease	autoimmune thyroid disease	ERBB3 SLC1A2 PNPT1 CTLA4	3.70e-03	126	147	4	EFO_0006812
Disease	Stomach Neoplasms	ERBB3 SLC1A2 KMT2C UBR5 ALDH7A1 SYMPK	3.83e-03	297	147	6	C0038356
Disease	urate measurement, bone density	FRAS1 ERBB4 ARHGAP22 EYS APOLD1 TAF4B DMBT1 TEX44 PDZD2	3.96e-03	619	147	9	EFO_0003923, EFO_0004531
Disease	laryngeal squamous cell carcinoma (is_marker_for)	ERBB3 ERBB4	3.99e-03	19	147	2	DOID:2876 (is_marker_for)
Disease	Usual Interstitial Pneumonia	HIF1A RTEL1	3.99e-03	19	147	2	C4721509
Disease	Hamman-Rich Disease	HIF1A RTEL1	3.99e-03	19	147	2	C4721508
Disease	anorectal malformation	RTEL1 CSMD2	3.99e-03	19	147	2	MONDO_0019938
Disease	Malignant neoplasm of stomach	ERBB3 SLC1A2 KMT2C UBR5 ALDH7A1 SYMPK	4.02e-03	300	147	6	C0024623
Disease	carcinoma (implicated_via_orthology)	ERBB3 ERBB4 SCRIB	4.04e-03	64	147	3	DOID:305 (implicated_via_orthology)
Disease	hepatocellular carcinoma (is_marker_for)	ERBB3 HIF1A SERPINF1 SF3B1 CTLA4 ALDH7A1	4.08e-03	301	147	6	DOID:684 (is_marker_for)
Disease	Familial Idiopathic Pulmonary Fibrosis	HIF1A RTEL1	4.42e-03	20	147	2	C4721952
Disease	essential tremor	PCDHA2 LRRTM3 SLC1A2 WNK2	4.85e-03	136	147	4	EFO_0003108
Disease	Stomach Carcinoma	ERBB3 UBR5	4.86e-03	21	147	2	C0699791
Disease	Arthrogryposis	VPS8 LGI4	4.86e-03	21	147	2	C0003886
Disease	Idiopathic Pulmonary Fibrosis	HIF1A RTEL1	4.86e-03	21	147	2	C1800706
Disease	cardiac troponin T measurement	GABRG3 LRRTM3 SLC14A2 WNK2 CNTFR	4.90e-03	219	147	5	EFO_0005043

Protein segments in the cluster

Peptide	Gene	Start	Entry
PVIALGATLGTATSI	SYT13	6	Q7L8C5
TSPEIVTALAIAGTL	ACO2	491	Q99798
ISTADLPVARISAGT	AKAP14	121	Q86UN6
TVLTAALLLSGIPAE	CAMLG	241	P49069
NLATTTLGSALSLPV	ERBB3	1021	P21860
VSLLVAAGTVQPSDS	ERBB4	11	Q15303
RGVPALVALVASSQS	ARVCF	801	O00192
ASVSSSPARALLLVG	BRI3BP	116	Q8WY22
LTGFQLPATIVSAAT	CSMD2	96	Q7Z408
LPATIVSAATTLSLR	CSMD2	101	Q7Z408
LPVVSNAAFLTGSIS	C2orf78	51	A6NCI8
SSVGTPLARASIKSA	CACNA1E	436	Q15878
LSLVVPSALFAAVGT	ALDH7A1	311	P49419
IRATSGAATPVIAST	BNC2	511	Q6ZN30
VILIPVLVSSAGTSA	C1QL3	6	Q5VWW1
VTVSVSTAVPAASAL	ARMH4	296	Q86TY3
VLSLISSLGFNTPIA	MASTL	211	Q96GX5
VAALLTLPVTLASGA	ACKR1	176	Q16570
LALSSGASLLIVPTS	AASDH	251	Q4L235
TPLSTLAIVALGTGI	NPR2	451	P20594
AVLGVPSSLASSVLG	CD72	46	P21854
TPIIATLSSGAVAAL	SLC7A2	386	P52569
VPLSLFSVAAVAGTV	DISP2	986	A7MBM2
STIAPALISSGLSVV	ENO2	71	P09104
ASSILGVFVLTPSLA	GKN3P	6	P0CG01
TISVSLAVAAIPEGL	ATP2C1	296	P98194
AAPARVALGITTVLT	GLRA3	281	O75311
ARIPAVTLAVTSVAG	MTCL1	181	Q9Y4B5
STVPSGLVSSISRVL	PAX7	146	P23759
SLPISENASLGTVIA	PCDHA2	356	Q9Y5H9
SLVAAVSIPGNLFSL	P2RY8	31	Q86VZ1
VLATSGIISPSTFAL	LRFN5	221	Q96NI6
TPLLLAATSGALDTI	ANKAR	641	Q7Z5J8
AIVGLSLSPVTLGTS	APOLD1	101	Q96LR9
SLSPVTLGTSLLVSA	APOLD1	106	Q96LR9
LATPITTLGTIATLS	HCFC1	906	P51610
NVSLSTAIVADLGSP	MFSD10	156	Q14728
VALSTLPAGTTGSLV	MUC16	2746	Q8WXI7
SLSPNLSGTSVEILA	MUC16	10071	Q8WXI7
LTLTVSPAVSGLSSA	MUC16	11891	Q8WXI7
VLVAVATALVSASSP	IL11RA	11	Q14626
ASGSAVVLPLARIAT	IFI27	21	P40305
PRLAAGSSLSITVAS	FRAS1	1711	Q86XX4
ITGSTPVLSSLLANE	KMT2C	2911	Q8NEZ4
AVTSALSPEGVLSIQ	HSPB6	131	O14558
SVLPAASDGQSISLV	MAGEE1	271	Q9HCI5
IAASISATPVVSRGA	EYS	1451	Q5T1H1
TVAVASGAASTPISI	NFRKB	1141	Q6P4R8
ASPVVAGAVTLLVST	MBTPS1	416	Q14703
ALLVLTSPAATLLGS	GPAA1	546	O43292
GLTALSAIAISRTPV	GHITM	136	Q9H3K2
VASGPVALASTASAT	CRB2	546	Q5IJ48
PLVLGISLASSLVAS	ERVFC1-1	416	P60608
ALTLLAPAAGDTIIS	HIF1A	396	Q16665
ITVSGSAPVLSAVAT	CEACAM6	316	P40199
SAPVLSAVATVGITI	CEACAM6	321	P40199
ALASGSRPVSIISSI	KIF26B	1221	Q2KJY2
ILALSATPGSDIKAV	FANCM	241	Q8IYD8
LTSLALPGKAESVAS	PER2	651	O15055
DSLLTLPAIVSIAAG	PLXNA2	1231	O75051
VLIVVTITASPSLGS	OR4C46	41	A6NHA9
VSKAISAPLLGSSVD	PDZD2	1026	O15018
GTLVTLSSAPTAIKA	COPB1	266	P53618
VAISGLLTDQLSSPS	GPR119	56	Q8TDV5
SRAVSLLTSPAAGIK	MDM1	576	Q8TC05
TIPSVATATAAALGE	COG8	6	Q96MW5
TPLGALSVLVSAILS	NIPA2	86	Q8N8Q9
AIVTLGLAEPSTNIS	LRPPRC	811	P42704
DGLTALNISSPVSVA	PTPRZ1	1011	P23471
DAGTPSLSALTIVRV	PCDHGC3	431	Q9UN70
AVRVSFSSPLVAISG	PAPPA	1161	Q13219
TPALIFAITVATIGS	SLC2A14	31	Q8TDB8
SQAIPLVSVASVAAG	PNPLA7	296	Q6ZV29
EASLVAASTGVRALP	IFT172	1671	Q9UG01
LFTGLASATSAVAPI	POM121B	391	A6NF01
IILTATLATPSAATV	OBSCN	1736	Q5VST9
SAAGLLPTSILQSTE	MFSD2A	11	Q8NA29
TVSLPLKAVEALASG	FFAR1	56	O14842
LVQAAAVSTGPSLEL	CCDC175	16	P0C221
ATPARTALGITTVLT	GABRG3	281	Q99928
AGSIAAVAVTPLDVL	SLC25A18	231	Q9H1K4
TATLASVGAASIPSA	SLC1A2	431	P43004
AAPSVVLTVGLSAIR	FMNL3	546	Q8IVF7
LVSVPITLALAAAAA	CNTFR	351	P26992
QSLVASSVSPLIVSG	GON4L	1196	Q3T8J9
LVLAPFTAGTSLALT	APOL3	206	O95236
TVTLTVLSSPLALAG	HLA-DRB4	16	P13762
AVPFLVSATSGTTVL	CSAD	236	Q9Y600
ASAAPLGTTLAVQAV	ATF7IP	861	Q6VMQ6
LAASVVPTLTEFLAG	LYST	281	Q99698
GRVPKSASVSALSLI	MAST3	891	O60307
TLSSNLGLPVAVSTL	CEP192	31	Q8TEP8
AQPAVVLASSRGIAS	CTLA4	41	P16410
PVGALSSLAQTEVTL	ELP5	176	Q8TE02
EGSTSLSAPAVLVVA	ETNK1	61	Q9HBU6
ASTAGPESSLALRLV	DMBT1	851	Q9UGM3
VVALATDPNILSLSG	DHRS1	236	Q96LJ7
AASIPLGSLAAVGIS	SLC12A8	261	A0AV02
AASAVTVLLPETLGQ	SLC22A6	496	Q4U2R8
TLVTPLGALSVLISA	NIPAL1	141	Q6NVV3
PVTAATARTALSGLS	IL17RC	61	Q8NAC3
APSVGITRLINSSTA	PTPRA	26	P18433
AAAAALAAVVTTPLL	IRS4	21	O14654
PTLALSQVVAAASAL	IRS4	1126	O14654
ILTSGTLAPVSSFAL	RTEL1	476	Q9NZ71
VVSGTAVTLSLPAVT	TAF4B	456	Q92750
TPAVGALTSIVVLAA	PRR23A	51	A6NEV1
GSAVALVIAPTVLLT	LRRTM3	11	Q86VH5
SPTLLSLSLVRTGVT	LGI4	51	Q8N135
LATFQSAVAILGVPS	SLC5A6	76	Q9Y289
LTVPAVLTITFGLSA	PTCHD4	46	Q6ZW05
LVVTATASPPAGLLS	SLC39A4	16	Q6P5W5
ASVTILASASIPILA	PRRC2C	1851	Q9Y520
LASASIPILASALAS	PRRC2C	1856	Q9Y520
GVIPSTLAFALADTV	SIGMAR1	176	Q99720
VLARAGIPTSSVFAL	SETD3	356	Q86TU7
LAIGIAITATEVLPS	SIAH3	251	Q8IW03
ATPIAASLGDLITLS	SLC41A3	221	Q96GZ6
LPTAIAVSSLIAVGT	VPS8	156	Q8N3P4
AVSGPLAAATASILT	SLC25A44	226	Q96H78
AVSLLTAASPTIALL	SCRIB	931	Q14160
TLGVSLSSLGAIPAA	SREK1	21	Q8WXA9
PISSAVAGVAIGLVT	PNPT1	501	Q8TCS8
LDGAAVAVLSRTAPT	ARHGAP22	396	Q7Z5H3
PGAFTTLVSLSTINL	SLIT3	646	O75094
SLTAAGSLQVLSLTP	SPG11	56	Q96JI7
GQVPLTADVLAVSSS	TEX44	26	Q53QW1
IPAIATTTATVSGLV	UBA6	891	A0AVT1
VVSSARVAASLPSEG	ZNF503-AS2	76	A6NEH8
SAVASVAVDPSGRLL	WDR47	801	O94967
SPLSVATALSALSLG	SERPINF1	81	P36955
GGASSVPLSVLILSL	SLITRK5	656	O94991
PAIATTTAAVAGLLG	UBA7	851	P41226
AALQGTPLSATLSLV	RMND5B	46	Q96G75
SPVSISTTLALLSLG	SERPINA11	76	Q86U17
AFAVVASALGIPSLL	SF3B1	631	O75533
TGTPVAAATVAPILA	SAP130	371	Q9H0E3
SVTAVAALSGRPLGT	NDUFB5	11	O43674
SSRALVSTLVPLGLV	PIGR	636	P01833
LLPGAALTAAVFVAT	PIGZ	261	Q86VD9
IPAIATTTAAVVGLV	UBA1	891	P22314
PAISSINLTTALGSL	SYMPK	246	Q92797
PVSAAAIFLVGATTL	ZDHHC5	16	Q9C0B5
SSAAIPFGTLVAILA	TM9SF2	461	Q99805
PVATAAALLVGSSTL	ZDHHC8	16	Q9ULC8
VTASAGSLVLPVLVF	PIEZO1	1701	Q92508
AAGITQPLLTLASSA	WNK1	866	Q9H4A3
LLPAAVGAVSLATSQ	WNK2	1536	Q9Y3S1
GAIISATDPVTVLAI	SLC9A7	256	Q96T83
FTSPAVGSILAAIRA	TKFC	81	Q3LXA3
VGLLAALSVATPFET	SLC14A2	326	Q15849
TVLVASGALFITPTS	UGT2A1	51	P0DTE4
GVITTATSPAVALSA	YEATS2	951	Q9ULM3
LTTLATAVTGAALIA	TMEM198	171	Q66K66
FILAPAVGSLTTAAT	UBR5	1041	O95071
ATGVFVLSLSAIPVT	TM6SF1	6	Q9BZW5
ESSSPARGIAIVSVL	KCNA4	301	P22459
GTIVLPARSTTSVLL	MUC12	921	Q9UKN1
GTIVLPARSTTSVLL	MUC12	3561	Q9UKN1