Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionkinase binding

DOCK4 IL12RB2 ATN1 MAML1 NOX4 TNS2 IRS1 SRCIN1 WNK1 GAB2 PRKRA CD4 PER2 PKD1 LRP4 CEP152 ATF4

1.50e-0596910717GO:0019900
GeneOntologyMolecularFunctionprotein kinase binding

DOCK4 IL12RB2 ATN1 MAML1 NOX4 TNS2 IRS1 SRCIN1 WNK1 GAB2 PRKRA CD4 PKD1 LRP4 CEP152 ATF4

1.62e-0587310716GO:0019901
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

DOCK4 NOX4 IRS1 GAB2 CD4 LRP4

1.52e-041491076GO:1990782
GeneOntologyMolecularFunctiontranscription coactivator binding

GATA1 PPARD SIX1 STAT6

2.01e-04541074GO:0001223
GeneOntologyMolecularFunctionchromatin binding

GATA1 SIX1 RUVBL2 CRX TOX4 SUPT5H CHD5 SNAI2 FOXO4 ATF4 RERE TCF7L1

6.00e-0473910712GO:0003682
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

DMTF1 GATA1 SIX1 STAT6 CRX NKX2-8 KMT2D FOXO4 ATF4 ONECUT3

8.54e-0456010710GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

DMTF1 GATA1 SIX1 STAT6 CRX NKX2-8 KMT2D FOXO4 ATF4 ONECUT3

9.26e-0456610710GO:0001216
GeneOntologyMolecularFunctiontranscription coregulator binding

GATA1 PPARD SIX1 STAT6 PER2

9.45e-041401075GO:0001221
GeneOntologyBiologicalProcesscellular response to calcium ion

CPNE2 TRPM2 NCSTN WNK1 RASA4 RASA4B

6.15e-06881066GO:0071277
Domain-

HMG20A KMT2D TOX4 CHD5 TCF7L1

1.49e-055510651.10.30.10
DomainAtrophin-like

ATN1 RERE

3.19e-0521062IPR002951
DomainAtrophin-1

ATN1 RERE

3.19e-0521062PF03154
DomainHMG_box_dom

HMG20A KMT2D TOX4 CHD5 TCF7L1

3.37e-05651065IPR009071
DomainC2_dom

CPNE2 TNS2 FER1L6 C2CD2L RASA4 RASA4B TNS1

4.16e-051641067IPR000008
Domain-

RASA4 RASA4B

9.54e-05310624.10.1130.10
DomainTensin_PTB

TNS2 TNS1

1.90e-0441062IPR033929
DomainREJ

PKD1L2 PKD1

1.90e-0441062PS51111
DomainREJ_dom

PKD1L2 PKD1

1.90e-0441062IPR014010
DomainHMG_box

HMG20A KMT2D TOX4 TCF7L1

2.32e-04531064PF00505
DomainHMG

HMG20A KMT2D TOX4 TCF7L1

2.49e-04541064SM00398
Domain-

GATA1 PPARD RXRG RERE

3.07e-045710643.30.50.10
DomainZnf_NHR/GATA

GATA1 PPARD RXRG RERE

3.29e-04581064IPR013088
Domain-

TNS2 IRS1 GAB2 TBC1D4 RASA4 OSBPL7 RASA4B TNS1 SOS2

3.87e-0439110692.30.29.30
DomainPKD/REJ-like

PKD1L2 PKD1

4.72e-0461062IPR002859
DomainREJ

PKD1L2 PKD1

4.72e-0461062PF02010
DomainPH_dom-like

TNS2 IRS1 GAB2 TBC1D4 RASA4 OSBPL7 RASA4B TNS1 SOS2

7.17e-044261069IPR011993
DomainPTEN_C2

TNS2 TNS1

8.74e-0481062PF10409
DomainPTB

TNS2 TNS1

8.74e-0481062IPR013625
DomainPTEN_C2

TNS2 TNS1

8.74e-0481062SM01326
DomainPTB

TNS2 TNS1

8.74e-0481062PF08416
DomainC2_TENSIN

TNS2 TNS1

8.74e-0481062PS51182
DomainTensin_lipid_phosphatase_dom

TNS2 TNS1

8.74e-0481062IPR029023
DomainTensin_C2-dom

TNS2 TNS1

8.74e-0481062IPR014020
DomainBTK

RASA4 RASA4B

1.12e-0391062SM00107
DomainZnf_Btk_motif

RASA4 RASA4B

1.12e-0391062IPR001562
DomainPPASE_TENSIN

TNS2 TNS1

1.12e-0391062PS51181
DomainBTK

RASA4 RASA4B

1.12e-0391062PF00779
DomainZF_BTK

RASA4 RASA4B

1.12e-0391062PS51113
DomainLAM_G_DOMAIN

LAMA5 CNTNAP5 CNTNAP2

1.30e-03381063PS50025
DomainPTB

TNS2 TBC1D4 TNS1

1.51e-03401063SM00462
DomainLaminin_G_2

LAMA5 CNTNAP5 CNTNAP2

1.51e-03401063PF02210
Domain-

CPNE2 FER1L6 C2CD2L RASA4 RASA4B

1.56e-0314810652.60.40.150
DomainPTB/PI_dom

TNS2 TBC1D4 TNS1

1.62e-03411063IPR006020
DomainPKD_channel

PKD1L2 PKD1

1.70e-03111062PF08016
DomainPKD1_2_channel

PKD1L2 PKD1

1.70e-03111062IPR013122
DomainPH

IRS1 GAB2 RASA4 OSBPL7 RASA4B SOS2

1.96e-032291066PF00169
DomainLamG

LAMA5 CNTNAP5 CNTNAP2

1.99e-03441063SM00282
DomainZnF_GATA

GATA1 RERE

2.03e-03121062SM00401
DomainRasGAP

RASA4 RASA4B

2.78e-03141062SM00323
DomainRasGAP_CS

RASA4 RASA4B

2.78e-03141062IPR023152
DomainRasGAP

RASA4 RASA4B

3.19e-03151062PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

3.19e-03151062PS00509
DomainZnf_GATA

GATA1 RERE

3.19e-03151062IPR000679
DomainGATA

GATA1 RERE

3.19e-03151062PF00320
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

3.19e-03151062PS50018
DomainHMG_BOX_2

HMG20A TOX4 TCF7L1

3.57e-03541063PS50118
DomainGATA_ZN_FINGER_1

GATA1 RERE

3.64e-03161062PS00344
DomainGATA_ZN_FINGER_2

GATA1 RERE

3.64e-03161062PS50114
Domain-

RASA4 RASA4B

3.64e-031610621.10.506.10
DomainLaminin_G

LAMA5 CNTNAP5 CNTNAP2

4.37e-03581063IPR001791
DomainLH2

PKD1L2 PKD1

4.60e-03181062SM00308
DomainRasGAP_dom

RASA4 RASA4B

4.60e-03181062IPR001936
DomainPH

IRS1 GAB2 RASA4 OSBPL7 RASA4B SOS2

5.08e-032781066SM00233
DomainDSRM

ADARB1 PRKRA

5.12e-03191062SM00358
DomainPH_DOMAIN

IRS1 GAB2 RASA4 OSBPL7 RASA4B SOS2

5.17e-032791066PS50003
DomainPH_domain

IRS1 GAB2 RASA4 OSBPL7 RASA4B SOS2

5.26e-032801066IPR001849
Domaindsrm

ADARB1 PRKRA

5.67e-03201062PF00035
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPHK2 SZT2 CTC1 MAML1 LAMA5 IRS1 ATG2A EDC4 WNK1 REXO1 C2CD2L KMT2D PER2 CLCN7 ADAMTSL5 CHD5 PKD1 LRP4 DTX2

1.59e-0911051091935748872
Pubmed

A census of human transcription factors: function, expression and evolution.

DMTF1 GATA1 PPARD SIX1 RXRG STAT6 CRX NKX2-8 KMT2D TOX4 SNAI2 FOXO4 ATF4 RERE ONECUT3 TCF7L1

2.53e-089081091619274049
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

PPARD SIX1 RXRG HMG20A NKX2-8 TOX4 PER2 FOXO4 TCF7L1

1.56e-07263109920932939
Pubmed

Functional proteomics mapping of a human signaling pathway.

DMTF1 LAMA5 PPARD ANKLE2 PIAS1 HMG20A SEC24D KMT2D TOX4 SUPT5H PKD1 INVS

3.64e-075911091215231748
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

GATA1 PPARD SIX1 RXRG CRX NKX2-8 SNAI2 FOXO4 ATF4 ONECUT3 TCF7L1

1.20e-065441091128473536
Pubmed

Comparative genome mapping in the sequence-based era: early experience with human chromosome 7.

DOCK4 RASA4 RASA4B

1.66e-068109310810084
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

DMTF1 GATA1 PPARD SIX1 PIAS1 RXRG TOX4 PER2 SNAI2 FOXO4 ATF4 TCF7L1

2.43e-067091091222988430
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

GATA1 MAML1 PPARD SIX1 RUVBL2 RXRG STAT6 HMG20A PER2 SUPT5H ATF4 RERE VGLL1

3.84e-068771091320211142
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SZT2 MAML1 LAMA5 SRCIN1 NCSTN ATG2A ANKLE2 CHD5 CNTNAP2 LRP4

6.76e-065291091014621295
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

ATXN2L ATN1 MAML1 SIX1 FAM222B DTX2

8.82e-06152109638360978
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DMTF1 CRTC3 ATN1 PEX14 ATG2A WNK1 PIAS1 CHD5 SOS2

8.90e-06430109935044719
Pubmed

Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia.

DOCK4 CNTNAP5

9.73e-062109220346443
Pubmed

Tensin1 and a previously undocumented family member, tensin2, positively regulate cell migration.

TNS2 TNS1

9.73e-062109211792844
Pubmed

Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine.

ATN1 RERE

9.73e-062109210814707
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

9.73e-062109211448776
Pubmed

Screening of chromosomal region 21q22.3 for mutations in genes associated with neuronal Ca2+ signalling in bipolar affective disorder.

TRPM2 ADARB1

9.73e-062109216733555
Pubmed

A single administration of recombinant human interleukin-12 is associated with increased expression levels of interferon-gamma and signal transducer and activator of transcription in healthy subjects.

IL12RB2 PIAS1

9.73e-062109215901746
Pubmed

Stable over-expression of PPARβ/δ and PPARγ to examine receptor signaling in human HaCaT keratinocytes.

PPARD RXRG

9.73e-062109221843636
Pubmed

Signal transducer and activator of transcription-6 (STAT6) inhibition suppresses renal cyst growth in polycystic kidney disease.

STAT6 PKD1

9.73e-062109222025716
Pubmed

Induction of hyperproliferative fetal megakaryopoiesis by an N-terminally truncated GATA1 mutant.

GATA1 ITGA2B

9.73e-062109219682090
Pubmed

Gly972Arg of IRS-1 and Lys121Gln of PC-1 polymorphisms act in opposite way in polycystic ovary syndrome.

IRS1 PKD1

9.73e-062109227785750
Pubmed

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4.

PPARD ATF4

9.73e-062109223176727
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

9.73e-062109216041389
Pubmed

Mapping of transcription start sites of human retina expressed genes.

RBP3 CRX GUCY2D WDR17

1.23e-0545109417286855
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

DOCK4 ATXN2L VPS72 ENTR1 MAML1 WNK1 RUVBL2 PIAS1 TBC1D4 SUPT5H

1.68e-055881091038580884
Pubmed

Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.

DOCK4 IRS1 PTPN18 GAB2 SOS2

1.89e-05103109521706016
Pubmed

A-to-I RNA editing enzyme ADAR2 regulates light-induced circadian phase-shift.

ADARB1 PER2

2.91e-053109230287844
Pubmed

AXL phosphorylates and up-regulates TNS2 and its implications in IRS-1-associated metabolism in cancer cells.

TNS2 IRS1

2.91e-053109230419905
Pubmed

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).

SPHK2 ITGA2B

2.91e-053109223775711
Pubmed

CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.

RASA4 RASA4B

2.91e-053109225637021
Pubmed

C1-Ten is a protein tyrosine phosphatase of insulin receptor substrate 1 (IRS-1), regulating IRS-1 stability and muscle atrophy.

TNS2 IRS1

2.91e-053109223401856
Pubmed

RSV vaccine-enhanced disease is orchestrated by the combined actions of distinct CD4 T cell subsets.

GATA1 STAT6

2.91e-053109225769044
Pubmed

WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.

WNK1 FOXO4

2.91e-053109229904119
Pubmed

CD137 signaling induces macrophage M2 polarization in atherosclerosis through STAT6/PPARδ pathway.

PPARD STAT6

2.91e-053109232247042
Pubmed

SUMO modification regulates the transcriptional activity of MAML1.

MAML1 PIAS1

2.91e-053109220203086
Pubmed

Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells.

ATN1 RERE

2.91e-053109219131340
Pubmed

The NAD(P)H oxidase homolog Nox4 modulates insulin-stimulated generation of H2O2 and plays an integral role in insulin signal transduction.

NOX4 IRS1

2.91e-053109214966267
Pubmed

Expression of CD41 marks the initiation of definitive hematopoiesis in the mouse embryo.

GATA1 ITGA2B

2.91e-053109212393529
Pubmed

IL-13 upregulates GPIIb expression in megakaryocytic cell lines via STAT6.

ITGA2B STAT6

2.91e-053109220652946
Pubmed

Retinal dystrophies with bull's-eye maculopathy along with negative ERGs.

CRX GUCY2D

2.91e-053109230945053
Pubmed

The lung is an important site for priming CD4 T-cell-mediated protective immunity against gastrointestinal helminth parasites.

STAT6 CD4

2.91e-053109220605978
Pubmed

Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes.

IL12RB2 TRPM2

2.91e-053109221709234
Pubmed

RUVBL2, a novel AS160-binding protein, regulates insulin-stimulated GLUT4 translocation.

RUVBL2 TBC1D4

2.91e-053109219532121
Pubmed

Identification of targets of IL-13 and STAT6 signaling in polycystic kidney disease.

STAT6 PKD1

2.91e-053109229513071
Pubmed

Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis.

GATA1 STAT6

2.91e-053109224906147
Pubmed

Multiple roles of lymphatic vessels in peripheral lymph node development.

LAMA5 ITGA2B CD4

3.28e-0520109330355615
Pubmed

Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease.

IRS1 PPARD CUBN RXRG

3.64e-0559109420855565
Pubmed

ADARB1 catalyzes circadian A-to-I editing and regulates RNA rhythm.

ADARB1 PER2

5.82e-054109227893733
Pubmed

Essential role of MHC II-independent CD4+ T cells, IL-4 and STAT6 in contact hypersensitivity induced by fluorescein isothiocyanate in the mouse.

STAT6 CD4

5.82e-054109215096484
Pubmed

The orphan nuclear receptor ROR alpha and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease.

GATA1 STAT6

5.82e-054109228670633
Pubmed

Protein kinase WNK1 promotes cell surface expression of glucose transporter GLUT1 by regulating a Tre-2/USP6-BUB2-Cdc16 domain family member 4 (TBC1D4)-Rab8A complex.

WNK1 TBC1D4

5.82e-054109220937822
Pubmed

Identification of curcumin-inhibited extracellular matrix receptors in non-small cell lung cancer A549 cells by RNA sequencing.

LAMA5 ITGA2B

5.82e-054109228618934
Pubmed

Identification of an alternatively spliced variant of Ca2+-promoted Ras inactivator as a possible regulator of RANKL shedding.

RASA4 RASA4B

5.82e-054109216234249
Pubmed

T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemia.

STAT6 CD4

5.82e-054109211382732
Pubmed

Tensin3 is a negative regulator of cell migration and all four Tensin family members are downregulated in human kidney cancer.

TNS2 TNS1

5.82e-054109219194507
Pubmed

The eIF2α Kinase GCN2 Modulates Period and Rhythmicity of the Circadian Clock by Translational Control of Atf4.

PER2 ATF4

5.82e-054109231522764
Pubmed

Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities.

RASA4 RASA4B

5.82e-054109221460216
Pubmed

Type 2 immunity is controlled by IL-4/IL-13 expression in hematopoietic non-eosinophil cells of the innate immune system.

GATA1 STAT6

5.82e-054109216702603
Pubmed

Exploitation of the Polymeric Immunoglobulin Receptor for Antibody Targeting to Renal Cyst Lumens in Polycystic Kidney Disease.

STAT6 PKD1

5.82e-054109225922073
Pubmed

WNK1 phosphorylation sites in TBC1D1 and TBC1D4 modulate cell surface expression of GLUT1.

WNK1 TBC1D4

5.82e-054109231816312
Pubmed

Functional architecture of atrophins.

ATN1 RERE

5.82e-054109217150957
Pubmed

The orphan nuclear receptor RORα and group 3 innate lymphoid cells drive fibrosis in a mouse model of Crohn's disease.

GATA1 STAT6

5.82e-054109228783681
Pubmed

Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.

IL12RB2 PIAS1 PRKRA

8.29e-0527109319604093
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

DOCK4 ATXN2L CRTC3 CCDC18 IRS1 EDC4 WNK1 GAB2 TBC1D4 FOXO4 CEP152

8.51e-058611091136931259
Pubmed

IL-4-secreting eosinophils promote endometrial stromal cell proliferation and prevent Chlamydia-induced upper genital tract damage.

GATA1 STAT6

9.67e-055109228765368
Pubmed

FOXO1 cooperates with C/EBPδ and ATF4 to regulate skeletal muscle atrophy transcriptional program during fasting.

FOXO4 ATF4

9.67e-055109235061305
Pubmed

The phosphotyrosine-independent interaction of DLC-1 and the SH2 domain of cten regulates focal adhesion localization and growth suppression activity of DLC-1.

TNS2 TNS1

9.67e-055109217190795
Pubmed

Cutting edge: Eosinophils do not contribute to respiratory syncytial virus vaccine-enhanced disease.

GATA1 STAT6

9.67e-055109218981084
Pubmed

Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages.

GATA1 ITGA2B

9.67e-055109218371378
Pubmed

High-glucose-increased expression and activation of NADPH oxidase in human vascular smooth muscle cells is mediated by 4-hydroxynonenal-activated PPARα and PPARβ/δ.

NOX4 PPARD

9.67e-055109225722086
Pubmed

Liver sinusoidal endothelial cells link hyperinsulinemia to hepatic insulin resistance.

IRS1 FOXO4

9.67e-055109223349480
Pubmed

Sphingosine kinase 1 deficiency confers protection against hyperoxia-induced bronchopulmonary dysplasia in a murine model: role of S1P signaling and Nox proteins.

SPHK2 NOX4

9.67e-055109223933064
Pubmed

The homeodomain protein Meis1 is essential for definitive hematopoiesis and vascular patterning in the mouse embryo.

GATA1 ITGA2B

9.67e-055109215882575
Pubmed

Effect of five genetic variants associated with lung function on the risk of chronic obstructive lung disease, and their joint effects on lung function.

THSD4 TNS1

9.67e-055109221965014
Pubmed

A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome.

RBP3 RXRG CRX GUCY2D

1.26e-0481109416110338
Pubmed

The steroid receptor RNA activator protein is recruited to promoter regions and acts as a transcriptional repressor.

DMTF1 GATA1 ATF4

1.26e-0431109320398657
Pubmed

cAMP-response element (CRE)-mediated transcription by activating transcription factor-4 (ATF4) is essential for circadian expression of the Period2 gene.

PER2 ATF4

1.45e-046109221768648
Pubmed

CRY1/2 Selectively Repress PPARδ and Limit Exercise Capacity.

PPARD PER2

1.45e-046109228683290
Pubmed

Peroxisome proliferator-activated receptors modulate proliferation and angiogenesis in human endometrial carcinoma.

PPARD RXRG

1.45e-046109222205725
Pubmed

Tc17 cells mediate vaccine immunity against lethal fungal pneumonia in immune deficient hosts lacking CD4+ T cells.

IL12RB2 CD4

1.45e-046109222829762
Pubmed

SOCS1 restricts dendritic cells' ability to break self tolerance and induce antitumor immunity by regulating IL-12 production and signaling.

IL12RB2 CD4

1.45e-046109216357940
Pubmed

Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans.

GATA1 STAT6

1.45e-046109230897162
Pubmed

Trafficking of TRPP2 by PACS proteins represents a novel mechanism of ion channel regulation.

CLCN7 PKD1

1.45e-046109215692563
Pubmed

HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates.

CD4 ATF4

1.45e-046109214561767
Pubmed

Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM.

RUVBL2 SMG9

1.45e-046109233205750
Pubmed

IL-12 triggers a programmatic change in dysfunctional myeloid-derived cells within mouse tumors.

IL12RB2 CD4

1.45e-046109222056381
Pubmed

A human MAP kinase interactome.

CRTC3 WNK1 PIAS1 GAB2 TOX4 ATF4 TNS1 SOS2

1.52e-04486109820936779
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM2 PKD1L2 PKD1

1.53e-0433109319834762
Pubmed

Human transcription factor protein interaction networks.

ATN1 VPS72 ENTR1 GATA1 MAML1 MRPS16 EDC4 RUVBL2 PIAS1 HMG20A KMT2D CHD5 CEP152 RERE

1.54e-0414291091435140242
Pubmed

Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model.

CUBN PKD1 INVS

1.98e-0436109333737325
Pubmed

Mutations that are a common cause of Leber congenital amaurosis in northern America are rare in southern India.

CRX GUCY2D

2.02e-047109219753312
Pubmed

Histone deacetylase-associating Atrophin proteins are nuclear receptor corepressors.

ATN1 RERE

2.02e-047109216481466
Pubmed

High frequency of a retinoid X receptor gamma gene variant in familial combined hyperlipidemia that associates with atherogenic dyslipidemia.

PPARD RXRG

2.02e-047109217272748
Pubmed

Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity.

ATN1 RERE

2.02e-047109222510986
Pubmed

IL-4/IL-13 signaling beyond JAK/STAT.

IRS1 STAT6

2.02e-047109210856136
Pubmed

'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR.

STAT6 CD4

2.02e-047109217873878
Pubmed

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL.

GATA1 ITGA2B

2.02e-047109225995324
Pubmed

A dual activation and inhibition role for the paired immunoglobulin-like receptor B in eosinophils.

GATA1 STAT6

2.02e-047109218316626
Pubmed

Eosinophils and type 2 cytokine signaling in macrophages orchestrate development of functional beige fat.

GATA1 STAT6

2.02e-047109224906148
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

CRTC3 WDR46 NOX4 CUBN DIPK2B SUPT5H SERTAD4 FOXO4 DTX2 LRRN4 ALDH3B2 WDR17 INVS

2.09e-0412931091315342556
GeneFamilyC2 tensin-type domain containing|PTEN protein phosphatases|Phosphoinositide phosphatases

TNS2 TNS1

1.55e-045722902
GeneFamilyADAMTS like

THSD4 ADAMTSL5

3.24e-047722947
GeneFamilyDNAJ (HSP40) heat shock proteins|C2 tensin-type domain containing

TNS2 TNS1

4.31e-048722837
GeneFamilyINO80 complex |SRCAP complex

VPS72 RUVBL2

5.53e-0497221329
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

6.89e-0410722830
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

IRS1 GAB2 OSBPL7 RASA4B SOS2

1.38e-03206725682
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

GATA1 RERE

1.59e-031572282
CoexpressionGINESTIER_BREAST_CANCER_ZNF217_AMPLIFIED_DN

ATXN2L SPHK2 ATN1 SZT2 PPARD REXO1 KMT2D SMG9 FOXO4

1.13e-053381089M17094
CoexpressionVEGF_A_UP.V1_UP

TNS2 ADARB1 KMT2D PER2 GUCY2D PKD1 MN1

1.67e-051951087M2676
CoexpressionGSE18281_SUBCAPSULAR_CORTICAL_REGION_VS_WHOLE_MEDULLA_THYMUS_UP

SZT2 GATA1 PIAS1 TRIL CLCN7 FAM222B TCF7L1

1.91e-051991087M7254
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CRTC3 SLC6A17 LAMA5 SIX1 TNS1 TCF7L1

3.58e-07184109794748f63947db79a6b4540e3090a63689fdd9452
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 CRTC3 SLC6A17 LAMA5 SIX1 TNS1 TCF7L1

3.58e-071841097819b277ecced7b415e363c7e7ddbc6f3b2d296de
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

BOC DOCK4 ADARB1 TRIL SNAI2 LRP4 TNS1

4.60e-0719110973379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A|PND01-03-samps / Age Group, Lineage, Cell class and subclass

BOC DOCK4 ADARB1 SNAI2 SERTAD4 LRP4 TNS1

4.60e-071911097e7c605b56934d1383237c1f946dbccef25d91368
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DPP6 CUBN CSMD3 FER1L6 CNTNAP5 CNTNAP2

1.22e-061391096a1945b07f177cde40e7eea03a19236ce76165857
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-matrix_-_immature_3|E16.5-samps / Age Group, Lineage, Cell class and subclass

BOC DOCK4 RXRG TRIL SNAI2 SOS2

1.82e-061491096651494e84be03dc7b061ebdfa91756a1c507b9b4
ToppCellBasal_cells-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

PODNL1 SIX1 SNAI2 CNTNAP2 LRP4 VGLL1

3.41e-06166109623c04d1fba0c1733ccd0e4378fae2edde4fd0a7b
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 MBOAT1 TRPM2 GATA1 ITGA2B TBC1D4

4.32e-061731096120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 GATA1 GAB2 TBC1D4 CHD5

4.32e-06173109653e97835d7a518c278e7b90a0734eb0095d6aa33
ToppCelldroplet-Lung-LUNG-1m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 GATA1 GAB2 TBC1D4 CHD5

4.32e-061731096889a880de5fc19d26b82cfef3067869a28ef17ca
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 MBOAT1 TRPM2 GATA1 ITGA2B TBC1D4

4.32e-061731096b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTC1 CCDC18 PPARD PKD1L2 C2CD2L CHD5

4.93e-0617710961d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 GATA1 LAMA5 ITGA2B GAB2 TBC1D4

5.09e-06178109641745a589567ca5ea6d06331f4c8da03595b5f5c
ToppCellfacs-Marrow-T-cells-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 GATA1 LAMA5 ITGA2B GAB2 TBC1D4

5.09e-061781096eb940dd64c973f68bcaad6069d3bd56383329db5
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRTC3 SLC6A17 LAMA5 SIX1 TNS1 TCF7L1

5.78e-061821096ffe500d78a89dc6b4d05bab1664e7f30c94fb8d9
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

BOC ADARB1 TRIL SNAI2 LRP4 TNS1

6.96e-0618810963f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

DPP6 RXRG CNTNAP5 CHD5 CNTNAP2 SERTAD4

7.40e-0619010966e92c78799f34b31d098854503c796edb0dc7f80
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK4 NOX4 ADARB1 SNAI2 LRP4 TNS1

7.62e-061911096beb5bb42bd53bce01339da9110d374901548793c
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOCK4 NOX4 ADARB1 SNAI2 LRP4 TNS1

7.62e-0619110966609d85fd2577633dcc067507304a6f9e5865ca3
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

THSD4 LAMA5 SIX1 PER2 SNAI2 SERTAD4

9.36e-061981096f5b7013045b61fc56894f80092f799770dde1c8f
ToppCelldroplet-Liver-nan-3m-Myeloid-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 CTC1 EDC4 ANKLE2 INVS

1.53e-05127109539fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 ENTR1 TRPM2 MAML1 TBC1D4

1.91e-051331095f6e9a1301a3379847b215303a9b0c028841e2cc0
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 ENTR1 TRPM2 MAML1 TBC1D4

1.91e-051331095292ecfcadbaf15e0d34a3ab9bf511ab1065888bd
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

THSD4 CNTNAP5 CD4 TBC1D4 OSBPL7

2.53e-051411095c7043f3b024bb16bbc89e33075f5b6ced5cb9185
ToppCellAdult-Immune-enucleated_erythrocyte-D175|Adult / Lineage, Cell type, age group and donor

EDC4 FER1L6 SUPT5H CHD5 PZP

3.63e-051521095530d5427d8617dcb223d807b73abee0ef89285f3
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 GATA1 ITGA2B TBC1D4 CHD5

4.23e-051571095ed9c9feefc06c9536c03bedbc3397a2ee492a78e
ToppCellfacs-Marrow-T-cells-24m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 GATA1 ITGA2B TBC1D4 CHD5

4.23e-051571095fddcb24776b9f86e000208bae54541b15b2adefd
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BOC PODNL1 SNAI2 LRP4 VGLL1

4.77e-051611095da9eecf919866a9c579d7a707a996cf335213134
ToppCell343B-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

BOC PODNL1 SNAI2 LRP4 VGLL1

4.77e-051611095d431625c32f59a6b552191f3adc5198bd16ad5cf
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CPNE2 SZT2 SRCIN1 TBC1D4 SMG9

4.91e-05162109564353d33af0e82ebb7cf2bba74d52ca0586a58fc
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CPNE2 SZT2 SRCIN1 TBC1D4 SMG9

5.06e-0516310959f5facfa1864eb63e2f8022ad7379d9252b7a254
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 LAMA5 ITGA2B GAB2 TBC1D4

5.52e-051661095c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 LAMA5 ITGA2B GAB2 TBC1D4

5.52e-0516610950975fc165bcc7e85f053d9d0244fffe407c23571
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PODNL1 PEX14 SRCIN1 CSMD3 REXO1

5.68e-0516710953b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PODNL1 CCDC18 SMG9 CEP152 LRRN4

5.84e-051681095a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-mLTo|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC PODNL1 DPP6 LAMA5 PCBP4

6.18e-0517010957653f1205d4e62abe7e31b1d76f9bbd665e45667
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

IL12RB2 CSMD3 FER1L6 CNTNAP5 CNTNAP2

6.35e-051711095b2e753e811a7639956994609f73efcdb62d04f82
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 GATA1 ITGA2B TBC1D4

6.53e-0517210951b133be191252e7053faeacf9547730c3ae28d21
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 GATA1 ITGA2B TBC1D4

6.53e-051721095b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MBOAT1 GATA1 ITGA2B PTPN18 TBC1D4

6.71e-0517310958ca650542655c27516029e5bace97ff1b9dcc256
ToppCelldroplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MBOAT1 GATA1 ITGA2B GAB2 TBC1D4

6.71e-051731095117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MBOAT1 GATA1 ITGA2B PTPN18 TBC1D4

6.71e-0517310954282b47b33325472f52a4085986988911a372ed8
ToppCelldroplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MBOAT1 GATA1 ITGA2B GAB2 TBC1D4

6.71e-05173109501df9baeedf30e3a4891738554cdd300394dbb96
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 MBOAT1 GATA1 ITGA2B TBC1D4

6.89e-051741095009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL12RB2 ATG2A CD4 OSBPL7

6.89e-0517410951c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 MBOAT1 GATA1 ITGA2B TBC1D4

6.89e-05174109531f7127faabcb1092bb9827db625f57cf7d8240e
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

MBOAT1 GATA1 ITGA2B SIX1 TBC1D4

6.89e-051741095e9e4532a474b4b0938a50ff85c9508aca53cd3ae
ToppCellfacs-Lung-nan-3m-Lymphocytic-CD8+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PODNL1 IL12RB2 ATG2A CD4 OSBPL7

6.89e-0517410955491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCelldroplet-Lung-21m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPNE2 MBOAT1 GATA1 ITGA2B TBC1D4

6.89e-0517410958a8e98e62c2859c004b44dbce6974c9639ebeac6
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 ITGA2B TBC1D4 NPFF

7.08e-0517510951b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 ITGA2B TBC1D4 NPFF

7.08e-051751095a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MBOAT1 IRS1 CSMD3 CNTNAP5 TBC1D4

8.30e-05181109530729f0364f719c044712a51453e22dc2c1a232b
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

DOCK4 ADARB1 TRIL SNAI2 TNS1

8.52e-051821095ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCellfacs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 NOX4 ADARB1 SNAI2 TNS1

8.52e-051821095c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCellfacs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK4 NOX4 ADARB1 SNAI2 TNS1

8.52e-051821095dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

DPP6 GATA1 PPARD LRP4 PZP

8.52e-05182109568a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCellCOVID-19-kidney-Mito-rich_EC|kidney / Disease (COVID-19 only), tissue and cell type

BOC DOCK4 DIPK2B MN1 TCF7L1

8.75e-0518310953c4153479fc4ab2d073d92cee120480015555914
ToppCelldroplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NOX4 PEX14 ADARB1 SAMD10 FOXO4

8.75e-051831095dc9602bed3136db91faeffef177006246dc92743
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CTC1 TNS2 IRS1 ADAMTSL5 PKD1

8.75e-0518310953ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 TNS2 DIPK2B RASA4 RASA4B

8.75e-051831095a644258ba90acc62d571623e429d72ffc4b69203
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THSD4 BOC NKX2-8 ADAMTSL5 LRRN4

8.75e-051831095ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DOCK4 DIPK2B MN1 TCF7L1

8.97e-051841095688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC28A3 SEC24D SNAI2 SERTAD4 MN1

9.20e-0518510951b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE2 MBOAT1 LAMA5 ITGA2B TBC1D4

9.20e-0518510955527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCellControl-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

CPNE2 IL12RB2 MBOAT1 CD4 TBC1D4

9.20e-051851095e481cacda0b6b25f5f0062b962df9a442053ac30
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SZT2 SLC6A17 CSMD3 CNTNAP2 ONECUT3

9.44e-051861095bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

TRPM2 ADARB1 SAMD10 CHD5 CNTNAP2

9.68e-05187109561b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DOCK4 SNAI2 OSBPL7 MN1

1.02e-041891095e60a3d6aa84788c29f23439f1c747431ea581bc3
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC NOX4 TRIL LRP4 TNS1

1.02e-041891095c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RXRG CD4 CNTNAP2 SERTAD4 WDR17

1.02e-0418910953e8e30160a8d6f531ff743cb5918c9e79481f1bd
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC NOX4 TRIL LRP4 TNS1

1.02e-0418910952a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DOCK4 ADARB1 TRIL SNAI2 TNS1

1.02e-041891095dc5164591dea45b420798b94dda211be03daa70c
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RXRG CD4 CNTNAP2 SERTAD4 WDR17

1.02e-041891095851f8144aed5c7f80302911cd6b03f14bde7b56d
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

BOC NOX4 TRIL LRP4 TNS1

1.02e-0418910955a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 ADARB1 SNAI2 LRP4 TNS1

1.04e-04190109500fd993675faf53adf985b9316a18c8a33242029
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-FB-3|PND07-28-samps / Age Group, Lineage, Cell class and subclass

DOCK4 ADARB1 TRIL SNAI2 TNS1

1.04e-0419010951196b8ea2c44c7c80f5ee589dd517e6a413f2077
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

DOCK4 TRPM2 PPARD GAB2 MS4A6A

1.04e-041901095d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC NOX4 TRIL LRP4 TNS1

1.04e-0419010959cd147a174017ebda23cc47b6d4552d898acd092
ToppCellrenal_medulla_nuclei-Adult_normal_reference|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK4 DPP6 LRP4 RERE TCF7L1

1.04e-041901095f1363f7806cfc4f14fbc1b0e8dac2de813a88eee
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA5 TNS2 DIPK2B RASA4 RASA4B

1.04e-041901095141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOX4 ADARB1 SNAI2 LRP4 TNS1

1.04e-0419010958cda09d761c6b504a744959d587c183f94f1beeb
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NOX4 ADARB1 SNAI2 LRP4 TNS1

1.07e-04191109580484d39f34703a33b9bac09826b7a526e883cab
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NOX4 ADARB1 SNAI2 LRP4 TNS1

1.07e-0419110955c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

BOC DOCK4 DIPK2B TNS1 TCF7L1

1.07e-0419110952f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DPP6 CNTNAP5 CHD5 CNTNAP2 WDR17

1.07e-0419110955d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

DPP6 CNTNAP5 CHD5 CNTNAP2 WDR17

1.07e-04191109573dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

THSD4 IRS1 ADARB1 TRIL LRP4

1.10e-04192109572881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell5'-Adult-LargeIntestine-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD4 IRS1 TRIL SNAI2 TNS1

1.12e-041931095146e8c148478ab61b1c1dbaf1ee98a8cd4a0ff8a
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

THSD4 DOCK4 PPARD GAB2 RERE

1.12e-041931095779276e775cb2492e8dd36436295a536084a6415
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPP6 SRCIN1 CNTNAP5 CHD5 PCBP4

1.12e-041931095a189d46c39067b717509cd144e0225cc93d7731d
ToppCellPND01-03-samps-Mesenchymal|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DOCK4 TRIL SNAI2 LRP4 TNS1

1.15e-0419410954f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

TRPM2 MAML1 RASA4 OSBPL7 MS4A6A

1.15e-04194109558046894446cb250814252a23f60fdd59c114d77
ToppCellPND01-Mesenchymal-Mesenchymal_structural|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NOX4 ADARB1 TRIL SNAI2 TNS1

1.18e-0419510956bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NOX4 ADARB1 TRIL SNAI2 TNS1

1.18e-041951095a3b468125e48f072255cede7645f6692298ecf54
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

THSD4 DOCK4 DPP6 LRP4 RERE

1.21e-041961095ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast|PND01-03-samps / Age Group, Lineage, Cell class and subclass

DOCK4 TRIL SNAI2 LRP4 TNS1

1.21e-04196109554f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LAMA5 IRS1 SIX1 SNAI2 SERTAD4

1.21e-0419610953b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

THSD4 SIX1 SNAI2 CNTNAP2 LRP4

1.21e-04196109557df2a57b35be9851ac0b1e5731baa53052511f0
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NOX4 ADARB1 TRIL SNAI2 TNS1

1.24e-04197109506a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

BOC DOCK4 ADARB1 DIPK2B MN1

1.24e-041971095cd509e49bbdbf991cc5913960ff3ef275ad40628
DrugCarbarsone [121-59-5]; Up 200; 15.4uM; PC3; HT_HG-U133A

THSD4 ATN1 PPARD CUBN WNK1 CNTNAP2 CEP152 TNS1

3.69e-0619510683991_UP
Drugnordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A

ATXN2L PODNL1 ATN1 TNS2 ITGA2B C2CD2L CLCN7 CNTNAP2

4.13e-0619810685583_DN
DrugDelcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A

DOCK4 SPHK2 TRPM2 SIX1 CD4 GUCY2D CNTNAP2 TNS1

4.13e-0619810686033_UP
DrugDay8ra

BOC NPFF

2.15e-0521062CID000132122
DrugMethimazole [60-56-0]; Down 200; 35uM; PC3; HT_HG-U133A

ATXN2L ITGA2B PPARD WNK1 PTPN18 CLCN7 TNS1

3.17e-0519110673815_DN
DrugCarbarsone [121-59-5]; Up 200; 15.4uM; MCF7; HT_HG-U133A

ATXN2L SPHK2 ATN1 SZT2 CLCN7 RERE SOS2

3.39e-0519310673250_UP
Drugrosiglitazone maleate; Down 200; 10uM; PC3; HG-U133A

GATA1 SIX1 HMG20A MINDY3 CD4 ALDH3B2 SOS2

3.50e-051941067430_DN
DrugErgocryptine-alpha [511-09-1]; Up 200; 7uM; PC3; HT_HG-U133A

ATXN2L ITGA2B STAT6 C2CD2L CD4 CLCN7 SOS2

3.50e-0519410674552_UP
Drugphentolamine; Down 200; 11.5uM; MCF7; HT_HG-U133A_EA

DMTF1 LAMA5 EDC4 PTPN18 GAB2 SEC24D TBC1D4

3.62e-0519510671138_DN
DrugCP-690334-01 [459212-38-5]; Down 200; 1uM; MCF7; HT_HG-U133A

ATN1 TNS2 SIX1 WNK1 ADARB1 PCBP4 SOS2

3.62e-0519510673909_DN
DrugTolazamide [1156-19-0]; Up 200; 12.8uM; PC3; HT_HG-U133A

PPARD WNK1 ADARB1 PER2 CNTNAP2 TNS1 SOS2

3.62e-0519510674003_UP
DrugMetrizamide [31112-62-6]; Down 200; 5uM; MCF7; HT_HG-U133A

TNS2 SIX1 PTPN18 ADARB1 MINDY3 SNAI2 CEP152

3.74e-0519610673255_DN
DrugDecamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

SPHK2 SEC24D FAM222B SMG9 RERE PCBP4 SOS2

3.74e-0519610677353_DN
DrugNaloxone hydrochloride [357-08-4]; Up 200; 11uM; MCF7; HT_HG-U133A

TRPM2 PPARD ADARB1 CLCN7 CNTNAP2 LRP4 MN1

3.74e-0519610675606_UP
DrugNifenazone [2139-47-1]; Down 200; 13uM; PC3; HT_HG-U133A

SPHK2 PEX14 EDC4 SIX1 WNK1 PTPN18 PCBP4

3.74e-0519610677314_DN
DrugTrioxsalen [3902-71-4]; Down 200; 17.6uM; HL60; HT_HG-U133A

DOCK4 TRPM2 PPARD STAT6 C2CD2L TNS1 SOS2

3.74e-0519610672516_DN
DrugVigabatrin [60643-86-9]; Down 200; 31uM; HL60; HT_HG-U133A

SPHK2 CTC1 TNS2 IRS1 ADARB1 TBC1D4 PER2

3.86e-0519710672452_DN
DrugOrphenadrine hydrochloride [341-69-5]; Down 200; 13uM; PC3; HT_HG-U133A

ATXN2L ATN1 PPARD PER2 CNTNAP2 RERE TNS1

3.86e-0519710673801_DN
DrugFosfosal [6064-83-1]; Up 200; 18.4uM; PC3; HT_HG-U133A

IL12RB2 ATN1 MAML1 ITGA2B CHD5 CNTNAP2 TNS1

3.86e-0519710674239_UP
DrugDantrolene sodium salt [14663-23-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

SPHK2 ITGA2B ADARB1 CD4 CLCN7 FOXO4 MN1

3.86e-0519710673786_DN
DrugC75; Down 200; 10uM; PC3; HT_HG-U133A

PODNL1 EDC4 ADARB1 FAM222B CNTNAP2 PCBP4 VGLL1

3.86e-0519710676428_DN
Drugrotenone; Down 200; 1uM; PC3; HT_HG-U133A

ATN1 PPARD CNTNAP2 RERE TNS1 VGLL1 SOS2

3.86e-0519710675948_DN
DrugEserine sulfate, physostigmine sulfate [64-47-1]; Down 200; 6.2uM; MCF7; HT_HG-U133A

MAML1 PEX14 NCSTN ADARB1 MINDY3 TOX4 CLCN7

3.86e-0519710672768_DN
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; MCF7; HT_HG-U133A

DPP6 SPHK2 SZT2 CD4 RERE MS4A6A TCF7L1

3.99e-0519810673624_UP
DrugQuinethazone [73-49-4]; Up 200; 13.8uM; PC3; HT_HG-U133A

ATXN2L ITGA2B ATG2A ADARB1 STAT6 RERE SOS2

3.99e-0519810674529_UP
DrugNS-398; Up 200; 10uM; PC3; HT_HG-U133A

PPARD PTPN18 ADARB1 TOX4 CD4 CLCN7 MN1

3.99e-0519810676892_UP
DrugMethacycline hydrochloride [3963-95-9]; Up 200; 8.4uM; PC3; HT_HG-U133A

PPARD STAT6 C2CD2L CHD5 CNTNAP2 ALDH3B2 SOS2

3.99e-0519810674062_UP
DrugPentetic acid [67-43-6]; Down 200; 10.2uM; PC3; HT_HG-U133A

ATN1 WNK1 CD4 PER2 SUPT5H CNTNAP2 TNS1

3.99e-0519810674669_DN
DrugBetazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A

PODNL1 SPHK2 CTC1 WNK1 CLCN7 CNTNAP2 SOS2

3.99e-0519810675445_DN
DrugTropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A

SEC24D TOX4 TBC1D4 FAM222B SNAI2 RERE ALDH3B2

3.99e-0519810676264_DN
DrugSulfabenzamide [127-71-9]; Up 200; 14.4uM; PC3; HT_HG-U133A

ATXN2L PODNL1 ATN1 C2CD2L CNTNAP2 RERE SOS2

4.12e-0519910676634_UP
DrugAzathymine, 6 [932-53-6]; Up 200; 31.4uM; PC3; HT_HG-U133A

ATXN2L PPARD WNK1 ADARB1 CNTNAP2 RERE SOS2

4.12e-0519910673987_UP
Drugleukotoxin B (12,13-EODE); Down 200; 0.2uM; MCF7; HT_HG-U133A_EA

DMTF1 LAMA5 GAB2 C2CD2L SMG9 RERE ALDH3B2

4.12e-0519910671108_DN
DrugDNA-PK Inhibitor III; Down 200; 1uM; PC3; HT_HG-U133A

ATN1 TNS2 PTPN18 CNTNAP2 OSBPL7 TNS1 TCF7L1

4.12e-0519910677518_DN
DrugPepstatin A [26305-03-3]; Up 200; 5.8uM; PC3; HT_HG-U133A

CTC1 PPARD CLCN7 CNTNAP2 LRP4 VGLL1 SOS2

4.12e-0519910674206_UP
DrugPHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT_HG-U133A

PODNL1 ATN1 GUCY2D CNTNAP2 LRP4 CEP152 SOS2

4.12e-0519910674330_UP
DrugBenzathine benzylpenicillin [5928-84-7]; Down 200; 4.2uM; HL60; HT_HG-U133A

TRPM2 MAML1 WNK1 STAT6 MINDY3 SEC24D FOXO4

4.25e-0520010672939_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A

DOCK4 WNK1 MINDY3 CNTNAP2 LRP4 CEP152 TNS1

4.25e-0520010671524_UP
DrugMePEG aldehyde

BOC CD4

6.42e-0531062CID003081726
Drugphorbol 12-myristate

DMTF1 SPHK2 GATA1 IRS1 ITGA2B CD4 PKD1

2.23e-042611067CID000107854
Drugmono-(2-ethylhexyl)phthalate

DPP6 IRS1 PPARD CUBN PTPN18 RXRG CNTNAP5 TBC1D4 PER2 CHD5 WDR17

2.50e-0465810611ctd:C016599
Drug2-propylpentanoic acid; Up 200; 500uM; PC3; HT_HG-U133A

SZT2 ITGA2B CLCN7 FOXO4 TNS1 TCF7L1

2.59e-0418910664464_UP
DrugRapamycin; Up 200; 0.1uM; PC3; HT_HG-U133A

PODNL1 SZT2 CLCN7 GUCY2D FOXO4 SOS2

2.90e-0419310664431_UP
DrugFurosemide [54-31-9]; Up 200; 12uM; PC3; HT_HG-U133A

THSD4 SPHK2 CLCN7 CNTNAP2 FOXO4 TNS1

2.90e-0419310664503_UP
DrugTrimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; PC3; HT_HG-U133A

ATN1 TRPM2 PTPN18 C2CD2L RERE SOS2

2.90e-0419310664202_DN
DrugTenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A

THSD4 PODNL1 SZT2 CNTNAP2 TNS1 TCF7L1

2.98e-0419410664182_UP
DrugThalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A

ITGA2B NKX2-8 CD4 CLCN7 RERE TNS1

2.98e-0419410662258_UP
DrugNitrofurantoin [67-20-9]; Down 200; 16.8uM; PC3; HT_HG-U133A

ATXN2L ITGA2B WNK1 PTPN18 PCBP4 SOS2

2.98e-0419410663674_DN
DrugThiocolchicoside [602-41-5]; Down 200; 7uM; MCF7; HT_HG-U133A

TNS2 MINDY3 SEC24D CLCN7 ALDH3B2 SOS2

3.06e-0419510662875_DN
DrugFlurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

ATXN2L SLC28A3 ADARB1 CD4 CHD5 INVS

3.06e-0419510666039_UP
DrugPentoxifylline [6493-05-6]; Up 200; 14.4uM; MCF7; HT_HG-U133A

TRPM2 ADARB1 SEC24D PER2 RERE TNS1

3.06e-0419510662290_UP
DrugDoxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A

ATXN2L ATN1 WNK1 ADARB1 FAM222B SOS2

3.06e-0419510664235_DN
DrugNaringenine [480-41-1]; Down 200; 14.6uM; PC3; HT_HG-U133A

PPARD ADARB1 SEC24D PCBP4 MN1 SOS2

3.06e-0419510664597_DN
DrugRaloxifene hydrochloride [82640-04-8]; Up 200; 7.8uM; MCF7; HT_HG-U133A

PPARD MINDY3 CLCN7 ALDH3B2 MS4A6A SOS2

3.06e-0419510666235_UP
Drug(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A

ATXN2L CTC1 ITGA2B PPARD ADARB1 PER2

3.06e-0419510663806_DN
DrugPapaverine hydrochloride [61-25-6]; Up 200; 10.6uM; MCF7; HT_HG-U133A

SPHK2 CTC1 TNS2 STAT6 HMG20A SOS2

3.06e-0419510666245_UP
DrugFluvastatin sodium salt [93957-55-2]; Up 200; 9.2uM; PC3; HT_HG-U133A

SPHK2 ATN1 ITGA2B ADARB1 OSBPL7 RERE

3.06e-0419510666691_UP
DrugMetaraminol bitartrate [33402-03-8]; Up 200; 8.6uM; PC3; HT_HG-U133A

ATN1 PPARD CD4 PER2 CNTNAP2 FOXO4

3.06e-0419510663669_UP
DrugPNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A

SZT2 ITGA2B PPARD CLCN7 RERE SOS2

3.06e-0419510663732_DN
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A

ATN1 CHD5 CNTNAP2 RERE TNS1 SOS2

3.06e-0419510662260_UP
DrugFluorometholone [426-13-1]; Up 200; 10.6uM; PC3; HT_HG-U133A

ATXN2L ITGA2B CUBN CD4 CLCN7 SNAI2

3.15e-0419610665771_UP
DrugPiribedil hydrochloride [78213-63-5]; Up 200; 12uM; HL60; HT_HG-U133A

PODNL1 SZT2 CTC1 PPARD WNK1 TNS1

3.15e-0419610662951_UP
DrugForskolin, from Coleus forskohlii; Down 200; 0.5uM; MCF7; HT_HG-U133A

ATXN2L ATN1 SIX1 CLCN7 ALDH3B2 SOS2

3.15e-0419610667055_DN
DrugNorfloxacin [70458-96-7]; Down 200; 12.6uM; PC3; HT_HG-U133A

TNS2 PTPN18 GAB2 C2CD2L CLCN7 SMG9

3.15e-0419610662090_DN
DrugClemizole hydrochloride [1163-36-6]; Down 200; 11uM; HL60; HT_HG-U133A

PTPN18 GAB2 TOX4 CD4 CLCN7 CEP152

3.15e-0419610662339_DN
DrugCisapride [81098-60-4]; Up 200; 8.6uM; MCF7; HT_HG-U133A

ATXN2L PODNL1 SPHK2 SZT2 FOXO4 SOS2

3.15e-0419610663305_UP
DrugLidocaone hydrochloride [73-78-9]; Up 200; 14.8uM; PC3; HT_HG-U133A

THSD4 ATXN2L ITGA2B C2CD2L CNTNAP2 OSBPL7

3.15e-0419610664596_UP
DrugAztreonam [78110-38-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A

PODNL1 PER2 CLCN7 OSBPL7 TNS1 SOS2

3.15e-0419610662282_UP
DrugTrichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A

ATXN2L SEC24D NKX2-8 KMT2D MS4A6A TCF7L1

3.15e-0419610665989_UP
DrugAcacetin [480-44-4]; Up 200; 14uM; MCF7; HT_HG-U133A

IL12RB2 ATN1 TNS2 PPARD MINDY3 PER2

3.15e-0419610663849_UP
Drug6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; HL60; HT_HG-U133A

ATXN2L SPHK2 WNK1 MINDY3 TNS1 SOS2

3.15e-0419610662925_DN
DrugATN-2

ATN1 RERE

3.18e-0461062CID003081684
DrugDorzolamide hydrochloride [130693-82-2]; Down 200; 11uM; PC3; HT_HG-U133A

SZT2 CTC1 SEC24D TBC1D4 FAM222B TNS1

3.24e-0419710665785_DN
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; MCF7; HT_HG-U133A

SPHK2 ATG2A ADARB1 PER2 CLCN7 SOS2

3.24e-0419710663886_DN
DrugAld1.1-H_000455; Up 200; 10uM; PC3; HT_HG-U133A

ATXN2L MAML1 ITGA2B PPARD C2CD2L PCBP4

3.24e-0419710667520_UP
DrugCyclacillin [3485-14-1]; Down 200; 11.8uM; PC3; HT_HG-U133A

ITGA2B PPARD SEC24D RERE TNS1 SOS2

3.24e-0419710663800_DN
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; MCF7; HT_HG-U133A

ATXN2L SPHK2 SZT2 CNTNAP2 TNS1 SOS2

3.24e-0419710664764_DN
DrugApomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; PC3; HT_HG-U133A

PODNL1 SPHK2 ATN1 WNK1 LRP4 INVS

3.24e-0419710666683_UP
DrugNadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A

ATXN2L TNS2 KMT2D CNTNAP2 TNS1 MN1

3.24e-0419710666091_UP
DrugTriamcinolone [124-94-7]; Up 200; 10.2uM; MCF7; HT_HG-U133A

THSD4 DOCK4 IL12RB2 ITGA2B TBC1D4 CHD5

3.24e-0419710662241_UP
DrugSertaconazole nitrate [99592-39-9]; Up 200; 8uM; PC3; HT_HG-U133A

ATN1 ITGA2B CD4 FOXO4 RERE MS4A6A

3.24e-0419710664475_UP
DrugPHA-00745360 [351320-33-7]; Up 200; 10uM; PC3; HT_HG-U133A

THSD4 ATN1 C2CD2L CD4 CLCN7 CNTNAP2

3.24e-0419710664559_UP
DrugTetrahydroxy-1,4-quinone monohydrate [319-89-1]; Up 200; 21uM; PC3; HT_HG-U133A

IL12RB2 SPHK2 PPARD CLCN7 ALDH3B2 SOS2

3.24e-0419710664078_UP
DrugFenofibrate [49562-28-9]; Up 200; 11uM; HL60; HT_HG-U133A

DOCK4 ATXN2L PODNL1 ATN1 IRS1 PCBP4

3.24e-0419710662401_UP
Drugnordihydroguaiaretic acid; Up 200; 1uM; MCF7; HG-U133A

CTC1 PPARD PIAS1 C2CD2L CD4 TCF7L1

3.24e-041971066203_UP
DrugSB 202190; Down 200; 1uM; MCF7; HT_HG-U133A

ATG2A EDC4 WNK1 PTPN18 SMG9 CEP152

3.24e-0419710666909_DN
DrugAmpyrone [83-07-8]; Up 200; 19.6uM; PC3; HT_HG-U133A

ATXN2L ATN1 SEC24D CD4 CLCN7 FOXO4

3.24e-0419710664507_UP
DrugSotalol hydrochloride [959-24-0]; Up 200; 13uM; MCF7; HT_HG-U133A

PODNL1 IL12RB2 TNS2 KMT2D CNTNAP2 LRP4

3.24e-0419710664160_UP
DrugPhentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; PC3; HT_HG-U133A

SPHK2 ATN1 PTPN18 STAT6 CLCN7 VGLL1

3.24e-0419710664336_DN
DrugMethocarbamol [532-03-6]; Up 200; 16.6uM; MCF7; HT_HG-U133A

CD4 LRP4 FOXO4 MS4A6A MN1 TCF7L1

3.24e-0419710662274_UP
DrugPiracetam [7491-74-9]; Up 200; 28.2uM; MCF7; HT_HG-U133A

IL12RB2 PTPN18 C2CD2L SEC24D LRP4 ALDH3B2

3.24e-0419710665462_UP
DrugSisomicin sulfate [53179-09-2]; Up 200; 2.8uM; PC3; HT_HG-U133A

WNK1 PER2 CNTNAP2 LRP4 MS4A6A SOS2

3.24e-0419710664014_UP
DrugEthotoin [86-35-1]; Up 200; 19.6uM; PC3; HT_HG-U133A

ATXN2L PPARD ADARB1 C2CD2L CD4 SOS2

3.24e-0419710664545_UP
DrugPNU-0230031 [267429-39-0]; Up 200; 1uM; MCF7; HT_HG-U133A

SPHK2 ITGA2B CLCN7 TNS1 TCF7L1 SOS2

3.24e-0419710663632_UP
DrugCeforanide [60925-61-3]; Down 200; 7.6uM; MCF7; HT_HG-U133A

MAML1 PEX14 TNS2 CD4 TBC1D4 CLCN7

3.24e-0419710663309_DN
DrugDeferoxamine mesylate [138-14-7]; Up 200; 6uM; MCF7; HT_HG-U133A

SPHK2 ATN1 SZT2 TNS2 PPARD LRP4

3.33e-0419810663842_UP
DrugTiclopidine hydrochloride [53885-35-1]; Up 200; 13.4uM; PC3; HT_HG-U133A

PPARD C2CD2L CNTNAP2 CEP152 RERE TNS1

3.33e-0419810664074_UP
DrugParomomycin sulfate [1263-89-4]; Down 200; 5.6uM; PC3; HT_HG-U133A

ATXN2L CTC1 PPARD ADARB1 FAM222B VGLL1

3.33e-0419810664595_DN
DrugNaringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT_HG-U133A

ATXN2L PODNL1 MAML1 ADARB1 STAT6 TNS1

3.33e-0419810663286_UP
DrugMetronidazole [443-48-1]; Up 200; 23.4uM; PC3; HG-U133A

PODNL1 ATN1 PEX14 ITGA2B PPARD MINDY3

3.33e-0419810661921_UP
Diseasedentatorubral-pallidoluysian atrophy (implicated_via_orthology)

ATN1 RERE

1.21e-0521032DOID:0060162 (implicated_via_orthology)
Diseaseurate measurement, bone density

THSD4 MBOAT1 LAMA5 PEX14 COL6A5 HMG20A CNTNAP5 TOX4 TCF7L1

3.24e-046191039EFO_0003923, EFO_0004531
Diseaseautosomal recessive intellectual developmental disorder (implicated_via_orthology)

CNTNAP5 CNTNAP2

3.33e-0481032DOID:0060308 (implicated_via_orthology)
DiseaseRETINITIS PIGMENTOSA

RBP3 CRX

5.33e-04101032268000
Diseaseintracranial aneurysm (is_implicated_in)

KMT2D PKD1

7.78e-04121032DOID:10941 (is_implicated_in)
Diseaseprostate carcinoma (is_implicated_in)

STAT6 ATF4

9.18e-04131032DOID:10286 (is_implicated_in)
DiseaseMalignant neoplasm of breast

BOC VPS72 CUBN WNK1 CRX KMT2D PER2 CHD5 SNAI2 TNS1 TCF7L1

1.33e-03107410311C0006142
Diseaseessential tremor

CPNE2 DPP6 CNTNAP5 FAM222B

1.34e-031361034EFO_0003108
DiseaseHETE measurement

DPP6 FER1L6 CNTNAP2

1.35e-03621033EFO_0801166
DiseaseLeber congenital amaurosis

CRX GUCY2D

1.40e-03161032cv:C0339527
Diseasevenous thromboembolism, fibrinogen measurement

ATXN2L LRP4 MS4A6A

1.68e-03671033EFO_0004286, EFO_0004623
Diseaserespiratory system disease

PEX14 STAT6 OSBPL7 RERE

1.70e-031451034EFO_0000684
DiseaseFeeding difficulties

ATN1 MN1

1.78e-03181032C0232466
Diseasebreast size

DOCK4 PEX14 PZP

1.83e-03691033EFO_0004884
Diseasenasopharyngeal neoplasm

DPP6 SLC28A3 IRS1 CNTNAP2

1.97e-031511034EFO_0004252
Diseaseurinary microalbumin measurement

CUBN CNTNAP2

2.20e-03201032EFO_0010967
Diseaseschizophrenia (is_implicated_in)

ATN1 NCSTN CNTNAP2

2.60e-03781033DOID:5419 (is_implicated_in)
DiseaseAutosomal Recessive Primary Microcephaly

ANKLE2 CEP152

2.66e-03221032C3711387
DiseasePrimary microcephaly

DPP6 CEP152

2.66e-03221032C0431350
DiseaseLeber Congenital Amaurosis

CRX GUCY2D

2.66e-03221032C0339527
Diseaselongitudinal BMI measurement

DOCK4 SLC28A3 CNTNAP2

3.00e-03821033EFO_0005937
DiseaseAutism Spectrum Disorders

DPP6 DIPK2B CNTNAP2

3.32e-03851033C1510586

Protein segments in the cluster

PeptideGeneStartEntry
DGSLAYIATQGPLPH

PTPN18

96

Q99952
FYPNPLASSLGHLPS

ERFL

251

A0A1W2PQ73
LPDLSGPHSYSPGRN

ANKLE2

886

Q86XL3
GSESLPHSAAYPFLG

CEP152

1486

O94986
ASNGNPLDPSSLHYI

CPNE2

316

Q96FN4
VHDGPNLLSPLLGSY

CSMD3

951

Q7Z407
FLQHSSPGSPSLGLQ

CTC1

491

Q2NKJ3
GHSKGPYLVSAPLST

CHD5

746

Q8TDI0
ESYLGSPQHSPSTRG

ATF4

226

P18848
DSSSGLSQGPARPYH

ATN1

146

P54259
YADGLHPTGNITGLP

C19orf18

26

Q8NEA5
YGDDPQSSPNLGHII

ALDH3B2

191

P48448
HLGLPPDSLLSYPAN

DIPK2B

86

Q9H7Y0
HLQPTGTPGTYLLQT

DMTF1

501

Q9Y222
SGGHLPQASPISVYL

ATG2A

1301

Q2TAZ0
QNLYHPGALTGTPPS

ATXN2L

911

Q8WWM7
VSINNTGLLGSYHPG

RASA4

671

O43374
SGSYIHLEPVAGTLP

PZP

451

P20742
VSINNTGLLGSYHPG

RASA4B

671

C9J798
PSSAYNGDLNGLLVP

EDC4

36

Q6P2E9
LGDGPLQHYIAVSSP

NCSTN

546

Q92542
LHLNGGSNPSESFPL

MAML1

196

Q92585
KGATIPYHPSLSLGT

PCBP4

176

P57723
EPLIDPVYGHGSQSL

MINDY3

206

Q9H8M7
LADSSNTSPGLYPHL

MAGEB6

376

Q8N7X4
SGPSQHLDSPNIGVY

GUCY2D

541

Q02846
HSIPLGQADPSLAPY

DTX2

61

Q86UW9
LATTGLNHPEVPYSS

HMG20A

26

Q9NP66
AGDLPTHDGYLPSNI

IL12RB2

791

Q99665
SLFHDPPGSYNPLTL

CLCN7

476

P51798
LQPVPHSGSSGYGSL

PER2

471

O15055
HPGVTGPLHTYSSSL

FOXO4

331

P98177
LHSRQPGSASALGYP

FAM205A

1301

Q6ZU69
PGPGDLSFQLLSHTQ

FAM222B

6

Q8WU58
LYTHLPLDGFPSAAG

LAMA5

1046

O15230
PGSALGLFPAYQHLA

NKX2-8

216

O15522
KGPSTLTAPNGHYIL

IRS1

471

P35568
PGLQYTLLSQTGPVH

ADARB1

91

P78563
PDGTQDQLLLPHAGY

ADAMTSL5

446

Q6ZMM2
GLLKYQTNLDTHPPG

NOX4

211

Q9NPH5
ANTTLVSNLYGHPPG

PKD1L2

2001

Q7Z442
TLHLYGNGLDRVPPA

PODNL1

341

Q6PEZ8
PTLLYEHPETSGLGL

FBXO43

101

Q4G163
GIFYGSNLPPTIISH

CUBN

1121

O60494
SGLTLGPPGTAHLYQ

GATA1

351

P15976
LPGHQASGQPYLSGI

BOC

911

Q9BWV1
YHSPGLISNSPVLSG

DOCK4

1831

Q8N1I0
HYEEGSPRNLGTPTS

C2CD2L

406

O14523
LDVQPSHPGLLNYSP

CCDC18

66

Q5T9S5
LGLDHNSPPSQTGGY

ENTR1

141

Q96C92
GGSLPDLTNLHYSTP

CRTC3

271

Q6UUV7
FQGHPQLESYLPGIL

COL6A5

1211

A8TX70
HLTLPQALPQYAGSG

CD4

281

P01730
PGSVLFLPHSYIGNS

MS4A6A

216

Q9H2W1
GSTYLHPLSELLGIP

MBOAT1

16

Q6ZNC8
YLAGLTGHVSSPPVN

GPR156

241

Q8NFN8
LGSNQLGPIYGHTSV

CNTNAP2

251

Q9UHC6
PLAGNYSHPGASVDL

MT-CO1

131

P00395
HYPLLLVVDGTPGSQ

DPP6

621

P42658
NPGPHYSVNALALSG

CRX

6

O43186
VNSSGSYLLLPGTPQ

CNTNAP5

371

Q8WYK1
ATARQHPLYGLSPGT

LRRN4

631

Q8WUT4
SPGSRDPAGSYHLNL

PKD1

2981

P98161
LLPYVHGNQSSPELG

PKD1

3731

P98161
SGTRGLPPTDYAHLQ

OSBPL7

286

Q9BZF2
GTIPSDSQGATPLHY

INVS

281

Q9Y283
LGGTYTTLTPLQHLP

ONECUT3

101

O60422
ALDNHLSPSAYPGLP

MN1

481

Q10571
ISGQVHGFYSLPKPS

GAB2

241

Q9UQC2
SKGAGTNHPPSNLLY

FER1L6

806

Q2WGJ9
LGSYDPLPNSHGEKL

MRPS16

51

Q9Y3D3
RGTSYQSPHGIPIDL

RUVBL2

336

Q9Y230
SPVTTYHLQRALPGG

SZT2

2976

Q5T011
PLAFDYSPGSHGLLS

REXO1

146

Q8N1G1
PNHGQTRLPGYSSAE

SOS2

471

Q07890
GGPQHALPSSSYTDL

PPARD

31

Q03181
HAQLPNGLSPLSGYS

SNAI2

66

O43623
LLPGYRGHPSFQSLV

SMG9

456

Q9H0W8
YSLPGLTASQPSHGL

SIX1

246

Q15475
LYHTSPSLGGLTRPV

SAMD10

101

Q9BYL1
IGPDYVTGSNLPSHS

WDR17

1256

Q8IZU2
TPLQDGSRTPHYGSQ

SUPT5H

791

O00267
GTSPAAAYPHTSLQL

RERE

886

Q9P2R6
PGEVIPGGNHSLYSL

SLC28A3

656

Q9HAS3
SIHLPGQSQPSDLLY

ITGA2B

831

P08514
QLTYDGHPASSPLLP

PIAS1

96

O75925
PLAGSHYRGISNPIT

SERTAD4

56

Q9NUC0
LPPQDAQTSGSLLHY

NPFF

41

O15130
HSPEGSTVTYHLLGP

PEX14

281

O75381
NESPLYLVNHGESGP

SEC24D

346

O94855
LLLSYFQGPEAGPVH

RBP3

491

P10745
ASTPLLHGEFGSYPA

SPHK2

46

Q9NRA0
EPLYAAFPGSHLTNG

SRCIN1

261

Q9C0H9
LTPLITYSNDHFSPG

TCF7L1

191

Q9HCS4
GSLGAQPLLQPSHYG

STAT6

816

P42226
QPLLQPSHYGQSGIS

STAT6

821

P42226
RSFHGPYTVQAGLPL

TRPM2

1311

O94759
PSPHDVLTYSLGGNF

TRIL

56

Q7L0X0
SHPLTQSRSGYIPSG

TNS1

756

Q9HBL0
LSAVGTPLNALGSPY

RXRG

56

P48443
LPSQGPEYVIHGLTS

TRAV26-2

56

A0A0B4J265
TYQPLSTRTLPHGAG

WDR46

391

O15213
THPYFSVQLGPGQLS

TBC1D4

976

O60343
RLPEYTLSQEGGPAH

PRKRA

141

O75569
HRSYLGPGSTSPLET

SLC6A17

691

Q9H1V8
YITAHGLPPTASALG

VPS72

326

Q15906
GVSSYISQPGGLHPL

WNK1

1556

Q9H4A3
HGPLYQSDSGPRSGL

THSD4

221

Q6ZMP0
LAGTSSLEPGYSHPF

VGLL1

136

Q99990
LTHTRGPLDGSPYAQ

TNS2

471

Q63HR2
GNDNYLTITGPSHPF

TOX4

6

O94842
PDGSLPYLSHGASQR

KMT2D

2621

O14686
IGSQLPHPFGLTLYG

LRP4

941

O75096