Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	RALA RALB NLRP1 ERCC6 DNAH12 RRAGD DNAH10 MCM9 RRAGC	9.50e-07	775	29	9	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	RALA RALB NLRP1 ERCC6 DNAH12 RRAGD DNAH10 MCM9 RRAGC	1.83e-06	839	29	9	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	RALA RALB NLRP1 ERCC6 DNAH12 RRAGD DNAH10 MCM9 RRAGC	1.85e-06	840	29	9	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	RALA RALB NLRP1 ERCC6 DNAH12 RRAGD DNAH10 MCM9 RRAGC	1.85e-06	840	29	9	GO:0016818
GeneOntologyMolecularFunction	GDP binding	RALA RALB RRAGD RRAGC	1.44e-05	103	29	4	GO:0019003
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH12 DNAH10	3.07e-04	18	29	2	GO:0008569
GeneOntologyMolecularFunction	ATP hydrolysis activity	NLRP1 ERCC6 DNAH12 DNAH10 MCM9	3.94e-04	441	29	5	GO:0016887
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH12 DNAH10	7.52e-04	28	29	2	GO:0051959
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH12 DNAH10	1.31e-03	37	29	2	GO:0045505
GeneOntologyMolecularFunction	GTPase activity	RALA RALB RRAGD RRAGC	1.42e-03	341	29	4	GO:0003924
GeneOntologyMolecularFunction	ATP-dependent activity	NLRP1 ERCC6 DNAH12 DNAH10 MCM9	1.74e-03	614	29	5	GO:0140657
GeneOntologyMolecularFunction	GTP binding	RALA RALB RRAGD RRAGC	2.47e-03	397	29	4	GO:0005525
GeneOntologyMolecularFunction	G protein activity	RALA RALB	3.31e-03	59	29	2	GO:0003925
GeneOntologyMolecularFunction	guanyl ribonucleotide binding	RALA RALB RRAGD RRAGC	3.54e-03	439	29	4	GO:0032561
GeneOntologyMolecularFunction	guanyl nucleotide binding	RALA RALB RRAGD RRAGC	3.54e-03	439	29	4	GO:0019001
GeneOntologyMolecularFunction	DNA helicase activity	ERCC6 MCM9	3.65e-03	62	29	2	GO:0003678
GeneOntologyMolecularFunction	microtubule motor activity	DNAH12 DNAH10	4.63e-03	70	29	2	GO:0003777
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	ERCC6 POLD1 MCM9	6.34e-03	262	29	3	GO:0140097
GeneOntologyMolecularFunction	kinase inhibitor activity	TESC WARS1	6.90e-03	86	29	2	GO:0019210
GeneOntologyMolecularFunction	kinase regulator activity	TESC ERCC6 WARS1	9.61e-03	305	29	3	GO:0019207
GeneOntologyMolecularFunction	ATPase binding	RALA RALB	1.07e-02	108	29	2	GO:0051117
GeneOntologyMolecularFunction	cytoskeletal motor activity	DNAH12 DNAH10	1.27e-02	118	29	2	GO:0003774
GeneOntologyBiologicalProcess	positive regulation of TORC1 signaling	RRAGD CLEC16A RRAGC	7.31e-05	56	30	3	GO:1904263
GeneOntologyBiologicalProcess	cellular response to starvation	RALB RRAGD CLEC16A RRAGC	1.43e-04	185	30	4	GO:0009267
GeneOntologyBiologicalProcess	positive regulation of TOR signaling	RRAGD CLEC16A RRAGC	1.96e-04	78	30	3	GO:0032008
GeneOntologyBiologicalProcess	response to light stimulus	NLRP1 ERCC6 FBXL21P FBXL3 POLD1	2.07e-04	382	30	5	GO:0009416
GeneOntologyBiologicalProcess	response to starvation	RALB RRAGD CLEC16A RRAGC	3.23e-04	229	30	4	GO:0042594
GeneOntologyBiologicalProcess	response to UV-B	NLRP1 ERCC6	4.22e-04	21	30	2	GO:0010224
GeneOntologyBiologicalProcess	regulation of TORC1 signaling	RRAGD CLEC16A RRAGC	4.33e-04	102	30	3	GO:1903432
GeneOntologyBiologicalProcess	TORC1 signaling	RRAGD CLEC16A RRAGC	5.25e-04	109	30	3	GO:0038202
GeneOntologyBiologicalProcess	cellular response to nutrient levels	RALB RRAGD CLEC16A RRAGC	5.38e-04	262	30	4	GO:0031669
GeneOntologyBiologicalProcess	negative regulation of autophagy	RRAGD CLEC16A RRAGC	5.69e-04	112	30	3	GO:0010507
GeneOntologyBiologicalProcess	entrainment of circadian clock by photoperiod	FBXL21P FBXL3	6.01e-04	25	30	2	GO:0043153
GeneOntologyBiologicalProcess	response to radiation	NLRP1 ERCC6 FBXL21P FBXL3 POLD1	7.28e-04	503	30	5	GO:0009314
GeneOntologyBiologicalProcess	photoperiodism	FBXL21P FBXL3	7.55e-04	28	30	2	GO:0009648
GeneOntologyBiologicalProcess	entrainment of circadian clock	FBXL21P FBXL3	8.67e-04	30	30	2	GO:0009649
GeneOntologyBiologicalProcess	positive regulation of epidermal growth factor receptor signaling pathway	RALA RALB	9.26e-04	31	30	2	GO:0045742
GeneOntologyBiologicalProcess	positive regulation of ERBB signaling pathway	RALA RALB	1.05e-03	33	30	2	GO:1901186
GeneOntologyBiologicalProcess	regulation of TOR signaling	RRAGD CLEC16A RRAGC	1.54e-03	158	30	3	GO:0032006
GeneOntologyCellularComponent	Gtr1-Gtr2 GTPase complex	RRAGD RRAGC	1.19e-05	4	30	2	GO:1990131
GeneOntologyCellularComponent	inner dynein arm	DNAH12 DNAH10	8.90e-05	10	30	2	GO:0036156
GeneOntologyCellularComponent	axonemal dynein complex	DNAH12 DNAH10	5.85e-04	25	30	2	GO:0005858
GeneOntologyCellularComponent	GTPase complex	RRAGD RRAGC	1.58e-03	41	30	2	GO:1905360
Domain	-	RALA RALB NLRP1 ERCC6 DNAH12 RRAGD DNAH10 MCM9 RRAGC	1.66e-06	746	30	9	3.40.50.300
Domain	Ral	RALA RALB	2.49e-06	2	30	2	IPR028412
Domain	P-loop_NTPase	RALA RALB NLRP1 ERCC6 DNAH12 RRAGD DNAH10 MCM9 RRAGC	4.75e-06	848	30	9	IPR027417
Domain	Gtr1_RagA	RRAGD RRAGC	1.49e-05	4	30	2	PF04670
Domain	Gtr1_RagA	RRAGD RRAGC	1.49e-05	4	30	2	IPR006762
Domain	ATPase_dyneun-rel_AAA	DNAH12 DNAH10	2.24e-04	14	30	2	IPR011704
Domain	Dynein_heavy_chain_D4_dom	DNAH12 DNAH10	2.24e-04	14	30	2	IPR024317
Domain	Dynein_heavy_dom-2	DNAH12 DNAH10	2.24e-04	14	30	2	IPR013602
Domain	DHC_N2	DNAH12 DNAH10	2.24e-04	14	30	2	PF08393
Domain	AAA_8	DNAH12 DNAH10	2.24e-04	14	30	2	PF12780
Domain	AAA_5	DNAH12 DNAH10	2.24e-04	14	30	2	PF07728
Domain	DHC_fam	DNAH12 DNAH10	2.59e-04	15	30	2	IPR026983
Domain	Dynein_heavy_dom	DNAH12 DNAH10	2.59e-04	15	30	2	IPR004273
Domain	Dynein_heavy	DNAH12 DNAH10	2.59e-04	15	30	2	PF03028
Domain	RAS	RALA RALB	1.44e-03	35	30	2	PS51421
Domain	AAA+_ATPase	DNAH12 DNAH10 MCM9	1.56e-03	144	30	3	IPR003593
Domain	AAA	DNAH12 DNAH10 MCM9	1.56e-03	144	30	3	SM00382
Domain	Small_GTPase_Ras	RALA RALB	1.60e-03	37	30	2	IPR020849
Domain	F-box-like	FBXL21P FBXL3	2.26e-03	44	30	2	PF12937
Domain	FBOX	FBXL21P FBXL3	3.15e-03	52	30	2	SM00256
Domain	F-box	FBXL21P FBXL3	5.17e-03	67	30	2	PF00646
Domain	FBOX	FBXL21P FBXL3	5.95e-03	72	30	2	PS50181
Domain	F-box_dom	FBXL21P FBXL3	6.44e-03	75	30	2	IPR001810
Pathway	PID_FOXO_PATHWAY	RALA RALB RBL2	6.66e-05	49	23	3	M136
Pathway	KEGG_MEDICUS_REFERENCE_EGF_EGFR_RAS_RALGDS_SIGNALING_PATHWAY	RALA RALB	1.39e-04	11	23	2	M47436
Pathway	REACTOME_P38MAPK_EVENTS	RALA RALB	1.96e-04	13	23	2	M1441
Pathway	KEGG_MEDICUS_REFERENCE_FLCN_MTORC1_SIGNALING_PATHWAY	RRAGD RRAGC	2.29e-04	14	23	2	M47922
Pathway	KEGG_MEDICUS_REFERENCE_GATOR1_MTORC1_SIGNALING_PATHWAY	RRAGD RRAGC	2.29e-04	14	23	2	M47918
Pathway	REACTOME_SIGNALLING_TO_RAS	RALA RALB	4.75e-04	20	23	2	M12256
Pathway	REACTOME_MTORC1_MEDIATED_SIGNALLING	RRAGD RRAGC	6.88e-04	24	23	2	M3492
Pathway	REACTOME_MTORC1_MEDIATED_SIGNALLING	RRAGD RRAGC	7.47e-04	25	23	2	MM14650
Pathway	REACTOME_REGULATION_OF_PTEN_GENE_TRANSCRIPTION	RRAGD RRAGC	8.72e-04	27	23	2	MM15537
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH12 DNAH10	8.72e-04	27	23	2	M47755
Pathway	REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK	RRAGD RRAGC	1.01e-03	29	23	2	MM14980
Pathway	REACTOME_ENERGY_DEPENDENT_REGULATION_OF_MTOR_BY_LKB1_AMPK	RRAGD RRAGC	1.01e-03	29	23	2	M19861
Pathway	PID_P38_ALPHA_BETA_PATHWAY	RALA RALB	1.08e-03	30	23	2	M76
Pathway	REACTOME_SIGNALLING_TO_ERKS	RALA RALB	1.38e-03	34	23	2	M13881
Pathway	WP_TARGET_OF_RAPAMYCIN_SIGNALING	RRAGD RRAGC	1.55e-03	36	23	2	M39635
Pathway	REACTOME_MTOR_SIGNALLING	RRAGD RRAGC	2.01e-03	41	23	2	M27000
Pathway	REACTOME_MTOR_SIGNALLING	RRAGD RRAGC	2.11e-03	42	23	2	MM14638
Pathway	KEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT	DNAH12 DNAH10	2.21e-03	43	23	2	M47669
Pathway	KEGG_NUCLEOTIDE_EXCISION_REPAIR	ERCC6 POLD1	2.31e-03	44	23	2	M18937
Pathway	WP_NUCLEOTIDE_EXCISION_REPAIR	ERCC6 POLD1	2.31e-03	44	23	2	M39847
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT	DNAH12 DNAH10	2.42e-03	45	23	2	M47670
Pubmed	Ral GTPases in Schwann cells promote radial axonal sorting in the peripheral nervous system.	RALA RALB	7.19e-07	2	30	2	31201267
Pubmed	RalGTPases contribute to Schwann cell repair after nerve injury via regulation of process formation.	RALA RALB	7.19e-07	2	30	2	31201266
Pubmed	RalA and RalB differentially regulate development of epithelial tight junctions.	RALA RALB	7.19e-07	2	30	2	22013078
Pubmed	Differential involvement of RalA and RalB in colorectal cancer.	RALA RALB	7.19e-07	2	30	2	22790202
Pubmed	Ral GTPases regulate cell-mediated cytotoxicity in NK cells.	RALA RALB	7.19e-07	2	30	2	21810610
Pubmed	Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases.	RALA RALB	7.19e-07	2	30	2	26216878
Pubmed	Tissue-specific expression of GTPas RalA and RalB during embryogenesis and regulation by epithelial-mesenchymal interaction.	RALA RALB	7.19e-07	2	30	2	11025226
Pubmed	Ral GTPases in tumorigenesis: emerging from the shadows.	RALA RALB	7.19e-07	2	30	2	23830877
Pubmed	RalA and RalB proteins are ubiquitinated GTPases, and ubiquitinated RalA increases lipid raft exposure at the plasma membrane.	RALA RALB	7.19e-07	2	30	2	22700969
Pubmed	RAL GTPases mediate EGFR-driven intestinal stem cell proliferation and tumourigenesis.	RALA RALB	7.19e-07	2	30	2	34096503
Pubmed	RAL GTPases are linchpin modulators of human tumour-cell proliferation and survival.	RALA RALB	7.19e-07	2	30	2	12856001
Pubmed	Coding sequences of human ralA and ralB cDNAs.	RALA RALB	7.19e-07	2	30	2	2662142
Pubmed	Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs.	RALA RALB	7.19e-07	2	30	2	18756269
Pubmed	Geranylgeranyltransferase I inhibitors target RalB to inhibit anchorage-dependent growth and induce apoptosis and RalA to inhibit anchorage-independent growth.	RALA RALB	7.19e-07	2	30	2	17875936
Pubmed	Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.	RALA RALB	7.19e-07	2	30	2	17174914
Pubmed	Expression of ral GTPases, their effectors, and activators in human bladder cancer.	RALA RALB	7.19e-07	2	30	2	17606711
Pubmed	Ral isoforms are implicated in Fc gamma R-mediated phagocytosis: activation of phospholipase D by RalA.	RALA RALB	7.19e-07	2	30	2	20679536
Pubmed	Mouse Platelet Ral GTPases Control P-Selectin Surface Expression, Regulating Platelet-Leukocyte Interaction.	RALA RALB	2.16e-06	3	30	2	29437579
Pubmed	The exocyst complex binds the small GTPase RalA to mediate filopodia formation.	RALA RALB	2.16e-06	3	30	2	11744922
Pubmed	RalA and RalB relocalization to depolarized mitochondria depends on clathrin-mediated endocytosis and facilitates TBK1 activation.	RALA RALB	2.16e-06	3	30	2	30995277
Pubmed	The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.	RRAGD RRAGC	2.16e-06	3	30	2	24095279
Pubmed	Ral GTPase-activating protein regulates the malignancy of pancreatic ductal adenocarcinoma.	RALA RALB	2.16e-06	3	30	2	34009715
Pubmed	Genetic deletion of RALA and RALB small GTPases reveals redundant functions in development and tumorigenesis.	RALA RALB	2.16e-06	3	30	2	23063435
Pubmed	Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone.	RALA RALB	2.16e-06	3	30	2	17709381
Pubmed	Ral-Arf6 crosstalk regulates Ral dependent exocyst trafficking and anchorage independent growth signalling.	RALA RALB	2.16e-06	3	30	2	27269287
Pubmed	Ral GTPase down-regulation stabilizes and reactivates p53 to inhibit malignant transformation.	RALA RALB	4.31e-06	4	30	2	25210032
Pubmed	Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.	RALA RALB	4.31e-06	4	30	2	7673236
Pubmed	RAL GTPases Drive Intestinal Stem Cell Function and Regeneration through Internalization of WNT Signalosomes.	RALA RALB	4.31e-06	4	30	2	30853556
Pubmed	Regulation of phospholipase C-delta1 through direct interactions with the small GTPase Ral and calmodulin.	RALA RALB	4.31e-06	4	30	2	15817490
Pubmed	rgr oncogene: activation by elimination of translational controls and mislocalization.	RALA RALB	7.18e-06	5	30	2	12874025
Pubmed	Ral GTPases are critical regulators of spinal cord myelination and homeostasis.	RALA RALB	7.18e-06	5	30	2	36170840
Pubmed	SH3BP4 is a negative regulator of amino acid-Rag GTPase-mTORC1 signaling.	RRAGD RRAGC	7.18e-06	5	30	2	22575674
Pubmed	Calmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human platelets.	RALA RALB	7.18e-06	5	30	2	12034722
Pubmed	A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dubé syndrome.	RRAGD RRAGC	7.18e-06	5	30	2	32612235
Pubmed	Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK.	RALA RALB	7.18e-06	5	30	2	19306925
Pubmed	Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.	RRAGD RRAGC	1.08e-05	6	30	2	24529380
Pubmed	The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1.	RRAGD RRAGC	1.08e-05	6	30	2	18497260
Pubmed	A novel human nucleolar protein, Nop132, binds to the G proteins, RRAG A/C/D.	RRAGD RRAGC	1.08e-05	6	30	2	14660641
Pubmed	Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases.	RRAGD RRAGC	1.08e-05	6	30	2	24081491
Pubmed	Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B.	RRAGD RRAGC	1.08e-05	6	30	2	11073942
Pubmed	Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling.	RRAGD RRAGC	1.51e-05	7	30	2	25259925
Pubmed	Competing E3 ubiquitin ligases govern circadian periodicity by degradation of CRY in nucleus and cytoplasm.	FBXL21P FBXL3	1.51e-05	7	30	2	23452855
Pubmed	FBXL21 regulates oscillation of the circadian clock through ubiquitination and stabilization of cryptochromes.	FBXL21P FBXL3	1.51e-05	7	30	2	23452856
Pubmed	Aberrant regulation of imprinted gene expression in Gtl2lacZ mice.	WARS1 RTL1	1.51e-05	7	30	2	16575184
Pubmed	Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral.	RALA RALB	1.51e-05	7	30	2	9422736
Pubmed	The GSK-3β-FBXL21 Axis Contributes to Circadian TCAP Degradation and Skeletal Muscle Function.	FBXL21P FBXL3	1.51e-05	7	30	2	32937135
Pubmed	Amino acid-dependent NPRL2 interaction with Raptor determines mTOR Complex 1 activation.	RRAGD RRAGC	2.01e-05	8	30	2	26582740
Pubmed	Amino acids activate mammalian target of rapamycin (mTOR) complex 1 without changing Rag GTPase guanyl nucleotide charging.	RRAGD RRAGC	2.58e-05	9	30	2	24337580
Pubmed	Ral GTPases regulate exocyst assembly through dual subunit interactions.	RALA RALB	3.22e-05	10	30	2	14525976
Pubmed	Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway.	RRAGD RRAGC	3.22e-05	10	30	2	22424946
Pubmed	Systems biology of facial development: contributions of ectoderm and mesenchyme.	VWA5A TPD52	3.94e-05	11	30	2	28363736
Pubmed	Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids.	RRAGD RRAGC	4.72e-05	12	30	2	20381137
Pubmed	Substrate binding promotes formation of the Skp1-Cul1-Fbxl3 (SCF(Fbxl3)) protein complex.	FBXL21P FBXL3	4.72e-05	12	30	2	24085301
Pubmed	Ras effectors and their role in mitogenesis and oncogenesis.	RALA RALB	4.72e-05	12	30	2	9297626
Pubmed	SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1.	RRAGD RRAGC	4.72e-05	12	30	2	25561175
Pubmed	A ubiquitin-binding domain in Cockayne syndrome B required for transcription-coupled nucleotide excision repair.	ERCC6 POLD1	5.58e-05	13	30	2	20541997
Pubmed	TBK1 Provides Context-Selective Support of the Activated AKT/mTOR Pathway in Lung Cancer.	RRAGD RRAGC	6.50e-05	14	30	2	28716898
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH12 DNAH10	6.50e-05	14	30	2	9373155
Pubmed	The deubiquitylase USP33 discriminates between RALB functions in autophagy and innate immune response.	RALA RALB	7.50e-05	15	30	2	24056301
Pubmed	RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly.	RALA RALB	9.70e-05	17	30	2	21241894
Pubmed	Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.	WARS1 CLEC16A VWA5A	1.17e-04	110	30	3	27889896
Pubmed	Nerve growth factor signaling, neuroprotection, and neural repair.	RALA RALB	2.31e-04	26	30	2	11520933
Pubmed	Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.	DNAH10 PLTP	3.08e-04	30	30	2	19936222
Pubmed	Identification of a family of human F-box proteins.	FBXL21P FBXL3	4.70e-04	37	30	2	10531035
Pubmed	Genetic variants in apoptosis and immunoregulation-related genes are associated with risk of chronic lymphocytic leukemia.	NLRP1 ERCC6 RBL2	4.91e-04	179	30	3	19074885
Pubmed	An approach based on a genome-wide association study reveals candidate loci for narcolepsy.	PLCXD2 GRK5 ACOX3	6.12e-04	193	30	3	20677014
Pubmed	A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci.	CLEC16A TPD52	6.65e-04	44	30	2	23817569
Pubmed	Identification of kidney mesenchymal genes by a combination of microarray analysis and Sall1-GFP knockin mice.	RRAGD VWA5A	7.59e-04	47	30	2	15172686
Interaction	TSC2 interactions	RALA RRAGD LMBR1L CLEC16A RRAGC	9.67e-06	196	30	5	int:TSC2
Interaction	WRNIP1 interactions	LMBR1L CLEC16A POLD1 MCM9	2.81e-05	119	30	4	int:WRNIP1
Interaction	LAMTOR4 interactions	RRAGD CLEC16A RRAGC	4.33e-05	46	30	3	int:LAMTOR4
Interaction	LAMTOR3 interactions	RALA RALB RRAGD RRAGC	5.46e-05	141	30	4	int:LAMTOR3
Interaction	SKP1 interactions	CLEC16A RBL2 FBXL21P FBXL3 POLD1 GRK5	6.77e-05	484	30	6	int:SKP1
Interaction	FRYL interactions	KIAA0930 FRYL GRK5	8.69e-05	58	30	3	int:FRYL
Interaction	RGL4 interactions	RALA RALB	9.57e-05	10	30	2	int:RGL4
GeneFamily	Dyneins, axonemal	DNAH12 DNAH10	9.91e-05	17	16	2	536
GeneFamily	F-box and leucine rich repeat proteins	FBXL21P FBXL3	1.53e-04	21	16	2	558
GeneFamily	RAS type GTPase family	RALA RALB	3.36e-04	31	16	2	389
Coexpression	GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_UP	RALB KIAA0930 PLTP POLD1 TPD52	3.00e-06	200	30	5	M8532
CoexpressionAtlas	Myeloid Cells, Mo.6C+II+.Bl, CD115+ B220- CD43+ Ly6C+ MHCIIint, Blood, avg-4	RALB NLRP1 KIAA0930 VWA5A PLTP GRK5 TPD52	1.28e-06	408	30	7	GSM605868_500
CoexpressionAtlas	Myeloid Cells, Mo.6C+II-.BM, B220neg CD3neg CD115+ Ly-6C+, Bone marrow, avg-3	RALB NLRP1 KIAA0930 PLTP GRK5 TPD52	1.53e-05	391	30	6	GSM854329_500
CoexpressionAtlas	Myeloid Cells, MF.Lv, CD45+ F4/80+ CD11b+, Liver, avg-2	RALB NLRP1 KIAA0930 PLTP GRK5 TPD52	1.79e-05	402	30	6	GSM854320_500
CoexpressionAtlas	Myeloid Cells, Mo.6C-II-.BM, B220neg CD3neg CD115+ Ly-6C/Glo CD43+, Bone marrow, avg-3	RALB KIAA0930 DNAH12 PLTP GRK5 TPD52	1.98e-05	409	30	6	GSM854332_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg5-.act.IEL, CD8a+ CD8b- TCRd+ Vg5- CD44hi, Small Intestine, avg-3	FRYL TESC RBL2 PLCXD2 PLTP	2.29e-04	402	30	5	GSM605808_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3	FRYL TESC RBL2 PLCXD2 PLTP	2.37e-04	405	30	5	GSM605811_500
CoexpressionAtlas	Myeloid Cells, Mo.6C+II-.Bl, Cd115+ B220- CD43+ Ly6C+ MHCII-, Blood, avg-3	RALB NLRP1 VWA5A GRK5 TPD52	2.53e-04	411	30	5	GSM605872_500
CoexpressionAtlas	Myeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2	RALB KIAA0930 PLTP GRK5 TPD52	2.59e-04	413	30	5	GSM605878_500
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3	RALB KIAA0930 PLTP GRK5 TPD52	2.99e-04	426	30	5	GSM605859_500
CoexpressionAtlas	Myeloid Cells, MF.Thio5.II+480int.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3	RALB KIAA0930 PLTP GRK5 TPD52	3.22e-04	433	30	5	GSM605856_500
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	UBE4A FRYL SELENOI MCM9	7.91e-06	191	30	4	9454f642c3621370fa23640b631301346b300950
ToppCell	healthy_donor-Myeloid-Monocytic-CD16+_Monocyte\|healthy_donor / Disease condition, Lineage, Cell class and subclass	RALB KIAA0930 TESC WARS1	8.41e-06	194	30	4	ecf746ef1c5c4d6d9ca06a6d3e3778670b5700c2
ToppCell	Nasal_Brush-Immune-Dendritic_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	RALA WARS1	1.38e-04	26	30	2	e83bba14028e7684beb3dd0ec5ecf8c88245a202
ToppCell	PND01-03-samps-Myeloid-Macrophage-macrophage-B\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DNAH12 DNAH10 POLD1	1.44e-04	152	30	3	5ce8920aedd39a4daf7082153b5e213707c14227
ToppCell	facs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UBE4A NLRP1 TPD52	1.44e-04	152	30	3	931c10245cde9b3290224cc1da46b2bf300b9ac2
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TESC PLCXD2 MCM9	2.10e-04	173	30	3	b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-Mast_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TESC DNAH12 VWA5A	2.10e-04	173	30	3	a7dee23b1d43d3070d502487af319ff81a9a747b
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TESC PLCXD2 POLD1	2.17e-04	175	30	3	849d8b09b19c10433d1a6a7c75e1f4e08b550954
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l5\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TESC RRAGD MCM9	2.21e-04	176	30	3	218a072882d387adbbad6916d7214099c7354465
ToppCell	3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RALB WARS1 GRK5	2.25e-04	177	30	3	16197068260fc062bf8b730a51a199887ea580b9
ToppCell	NS-critical-d_0-4-Myeloid-Mast_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TESC VWA5A MCM9	2.32e-04	179	30	3	6153e7a0eeae83e7d88f1a20093bf2113e8d66b1
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DNAH10 VWA5A MCM9	2.40e-04	181	30	3	338c7362d258a87f1a6b1a65376f5394d4b2b4b2
ToppCell	367C-Myeloid-Mast_cell\|367C / Donor, Lineage, Cell class and subclass (all cells)	RALB TESC VWA5A	2.40e-04	181	30	3	063fc83870f55f63c013f0276c1ec8f3abcbcf27
ToppCell	367C-Myeloid-Mast_cell-\|367C / Donor, Lineage, Cell class and subclass (all cells)	RALB TESC VWA5A	2.40e-04	181	30	3	e1161c9828ee94518eb5bef0b6228d71299c2f59
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_EM-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RALB ERCC6 GRK5	2.48e-04	183	30	3	a492b3827d2c368d33a7a5118748beaf4d7f6797
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TESC RBL2 FBXL21P	2.64e-04	187	30	3	fae08f34dc4b15352bd4d10bc6c924fe119b5d5e
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-immature_innate_lymphoid_cell-Ly6g5b+_T\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TESC RBL2 FBXL21P	2.64e-04	187	30	3	e6b140b9fb582abf07aa6ea9bc437de3ba0d6de1
ToppCell	Epithelial-Epithelial-D_(Ciliated)\|Epithelial / shred on cell class and cell subclass (v4)	DNAH12 DNAH10 PLTP	2.68e-04	188	30	3	8f30535a32968a81a304315a49c0d90a77d36948
ToppCell	tumor_Lung-MAST_cells-MAST\|tumor_Lung / Location, Cell class and cell subclass	RALB TESC VWA5A	2.72e-04	189	30	3	cd977962e01756b663728dae32ab9aba15bf7e22
ToppCell	3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RALB TESC VWA5A	2.72e-04	189	30	3	1893765b1e3b306f1e133101c28403070a70c3c8
ToppCell	3'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPPE CLEC16A ACOX3	2.72e-04	189	30	3	7dad62bd50c197838058e89abd0ee387de3e83cd
ToppCell	tumor_Lung-MAST_cells\|tumor_Lung / Location, Cell class and cell subclass	RALB TESC VWA5A	2.72e-04	189	30	3	300670be76454f197bd04f82c533579dd3671969
ToppCell	3'-Distal_airway-Immune_Myeloid_mast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RALB TESC VWA5A	2.72e-04	189	30	3	96566f84c796d5b2e31f64090555f2b258f0c9f2
ToppCell	3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RALB TESC VWA5A	2.72e-04	189	30	3	19b639bc6b35fe1d1079f60c8138aa946a95f3bf
ToppCell	3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RALB TESC VWA5A	2.72e-04	189	30	3	b59cc66f7bb9b72895b775fbcf1ec1dc08610969
ToppCell	3'-Distal_airway-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RALB TESC VWA5A	2.72e-04	189	30	3	f3cb1a8ddf7a4a95fb1b6e8fe5aa63ef037ca7a6
ToppCell	IPF-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	TESC WARS1 GRK5	2.72e-04	189	30	3	5c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	TESC WARS1 GRK5	2.77e-04	190	30	3	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TESC RRAGD DNAH10	2.77e-04	190	30	3	896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TESC RRAGD DNAH10	2.90e-04	193	30	3	ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCell	normal-na-Myeloid-non-classical_monocyte-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	RALB TESC WARS1	2.90e-04	193	30	3	053adc7ed9f997b503e12239a684bb9f5896e10c
ToppCell	Control-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	TESC WARS1 GRK5	2.90e-04	193	30	3	3479c01aaae7afd7e02d00e0cb21951c0106a0fd
ToppCell	PBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TESC RRAGD DNAH10	2.94e-04	194	30	3	23318a1b55895b5166c6151f488a94a09b4627ff
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	NLRP1 VWA5A GRK5	2.99e-04	195	30	3	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	moderate-Epithelial-Ciliated\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DNAH12 DNAH10 PLTP	2.99e-04	195	30	3	3486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell	control-Myeloid-CD16_Monocytes\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	KIAA0930 TESC WARS1	2.99e-04	195	30	3	f398d08a23fdfa6202f73a7aeac3ff4c997fbdfd
ToppCell	mild-Myeloid-CD16_Monocytes\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	KIAA0930 TESC WARS1	2.99e-04	195	30	3	e963d33b50d43e38cada738e41343b64e3d08b79
ToppCell	ICU-NoSEP-Myeloid-CD16_Mono\|ICU-NoSEP / Disease, Lineage and Cell Type	RALB TESC WARS1	3.03e-04	196	30	3	b15abb1c5396d038bab92b048795020199370f44
ToppCell	Macrophages-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	RALA KIAA0930 PLTP	3.03e-04	196	30	3	861c402ed8b8fde3582cc777c1357b45f5a2489b
ToppCell	IPF-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	RALA WARS1 GRK5	3.03e-04	196	30	3	8f0f72ead06abe02b575e443552eacc2151077ef
ToppCell	remission-Non-classical_Monocyte\|remission / disease stage, cell group and cell class	KIAA0930 TESC WARS1	3.03e-04	196	30	3	049d995986c20ce066bd64fcc2d2f1c2f8899883
ToppCell	(05)_Ciliated\|World / shred by cell type and Timepoint	DNAH12 DNAH10 PLTP	3.08e-04	197	30	3	fee3cd16af8eea697cd64e8f64af505aaa2ac4b0
ToppCell	proximal-Endothelial-Capillary-3\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRYL WARS1 GRK5	3.08e-04	197	30	3	ddb8ea895f0f34d4f20a0740b708fa0f3e378801
ToppCell	COPD-Endothelial-VE_Capillary_B\|Endothelial / Disease state, Lineage and Cell class	RALA WARS1 GRK5	3.08e-04	197	30	3	30dbc05ea66892d2e18ff375ffa86d1db7bc4083
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-non-classical_monocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RALB TESC WARS1	3.08e-04	197	30	3	1a82e0e74fc5fd71c490d98e8813d719b0b81aa6
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Serous-Serous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TESC PLTP TPD52	3.08e-04	197	30	3	40bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCell	proximal-Endothelial-Capillary\|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRYL WARS1 GRK5	3.08e-04	197	30	3	53baef54bd85c60ae24a3c163b3a3d937fb6ff0b
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Serous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TESC PLTP TPD52	3.08e-04	197	30	3	d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCell	proximal-3-Endothelial-Capillary\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FRYL WARS1 GRK5	3.08e-04	197	30	3	a1a61c03d67272693ec23e0d15f0a12bf618e2da
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RALB TESC WARS1	3.08e-04	197	30	3	1463522df1b6358cbe3b5022a3e153878e9c9e43
ToppCell	systemic_lupus_erythematosus-treated-Myeloid-non-classical_monocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RALB TESC WARS1	3.08e-04	197	30	3	46d8c7e9b3aff70bc58894282d0ec9e87d37235f
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RALB TESC WARS1	3.12e-04	198	30	3	9b47585653aaebd033c9b7bba93c7a7c35a4d60e
ToppCell	mild_COVID-19-Non-classical_Monocyte\|mild_COVID-19 / disease group, cell group and cell class (v2)	KIAA0930 TESC WARS1	3.12e-04	198	30	3	d7620b8d24e04ce1c563fc0ebe1625e03fe78950
ToppCell	remission-Non-classical_Monocyte\|World / disease stage, cell group and cell class	KIAA0930 TESC WARS1	3.12e-04	198	30	3	1c170655070acca00520b7cf9c510a04c0a90a8f
ToppCell	systemic_lupus_erythematosus-flare-Myeloid-non-classical_monocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	RALB TESC WARS1	3.12e-04	198	30	3	11b0d021114df73a539b04f76dd7c63f1fdbdf4f
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RALB TESC WARS1	3.12e-04	198	30	3	8b5d30312bbcabc6911ff03e5028766d77203dff
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-CD8+_T_naive\|Bac-SEP / Disease, condition lineage and cell class	DNAH12 DNAH10 RBL2	3.12e-04	198	30	3	a9a009e5eeb935232034635ad4a3c27d83c081ac
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RALB TESC WARS1	3.12e-04	198	30	3	cbbdd44dfa95370c0fbaa65ba71d86bfee0ea379
ToppCell	Control-Myeloid-Non-classical_Monocyte\|Control / Disease group, lineage and cell class	RALB TESC WARS1	3.12e-04	198	30	3	ae0a51e63e2751a6d9dc0c8a3852680949173523
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RALB TESC WARS1	3.12e-04	198	30	3	7d8fade2583c07a33dd83057cbce08e9fc77987a
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	RALB TESC WARS1	3.12e-04	198	30	3	3bc3dbd178043deadd7eef413b2761dc003abd6e
ToppCell	Healthy_donor-Non-classical_Monocyte\|Healthy_donor / disease group, cell group and cell class (v2)	KIAA0930 TESC WARS1	3.12e-04	198	30	3	d4eae333fa100db3ea2d4cbe7a1d6ab14816f0e2
ToppCell	Healthy/Control-Non-classical_Monocyte\|Healthy/Control / Disease group and Cell class	KIAA0930 TESC WARS1	3.12e-04	198	30	3	0badaf1fa5328d06291c3624d0f63196ffc81527
ToppCell	PBMC-Control-Myeloid-Non-classical_Monocyte\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RALB TESC WARS1	3.12e-04	198	30	3	165d60b111a17d517a420c434733eefb98da240d
ToppCell	CF-Myeloid-Monocyte_Macrophage\|CF / Disease state, Lineage and Cell class	RALA WARS1 PLTP	3.17e-04	199	30	3	bf95eacb31a4a847350f9d6e95ca76c6b730c400
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIAA0930 TESC WARS1	3.17e-04	199	30	3	3e09b3c2e2c57e5248981293020d2434e898e3e1
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	KIAA0930 TESC WARS1	3.17e-04	199	30	3	ae6b4b4557c6a9223acdee2a79bc780c5916d38a
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIAA0930 TESC WARS1	3.17e-04	199	30	3	99eec995aa20ac22a8dd045382bd15a15db0b87a
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIAA0930 TESC WARS1	3.17e-04	199	30	3	4eed28ef8c74d7131eeeabdd732a682d91e034dd
ToppCell	Bronchial-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CHIT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	KIAA0930 RRAGD PLTP	3.17e-04	199	30	3	54a54ad983503ed515d476882d86b17d97892037
ToppCell	tumor_Lung-Endothelial_cells-Tip-like_ECs\|Endothelial_cells / Location, Cell class and cell subclass	RALA WARS1 TPD52	3.17e-04	199	30	3	80c8641cfd84436eadf2234f1313749e2f73331f
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIAA0930 TESC WARS1	3.17e-04	199	30	3	f234533254fd82b1ef2041e8405fe201d874018b
ToppCell	Healthy_Control-Myeloid-Macrophages-FCN1-SPP1+\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	RALA KIAA0930 PLTP	3.17e-04	199	30	3	7437bc48a803ab8f153e5516a0aa0391ae3d97c7
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c5-CD16\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RALB TESC WARS1	3.17e-04	199	30	3	df946601b295be5419c09befbfa73f4314eef116
ToppCell	COVID-19_Convalescent-Myeloid-Non-classical_Monocyte\|COVID-19_Convalescent / Disease group, lineage and cell class	KIAA0930 TESC WARS1	3.17e-04	199	30	3	5253948a1d7fc3da571860e14cdde4e18222e13b
ToppCell	PBMC-Convalescent-Myeloid-Non-classical_Monocyte-Non-classical_Monocyte\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	KIAA0930 TESC WARS1	3.17e-04	199	30	3	aca9f75c690c6ed952bcbdc7e1e7eef7719f54ca
ToppCell	COVID-19-COVID-19_Convalescent-Myeloid-CD16+_Monocyte\|COVID-19_Convalescent / Disease, condition lineage and cell class	KIAA0930 TESC WARS1	3.22e-04	200	30	3	f24abb2d54d6423ee886285e3c66a874ec59e1a3
ToppCell	Control_saline-Hematopoietic_Myeloid-Dendritic_cells\|Control_saline / Treatment groups by lineage, cell group, cell type	NLRP1 RRAGD POLD1	3.22e-04	200	30	3	1559844b3116d41a69081e4ee89e64744a760181
ToppCell	Sepsis-ICU-NoSEP-Myeloid-CD16+_Monocyte\|ICU-NoSEP / Disease, condition lineage and cell class	RALB TESC WARS1	3.22e-04	200	30	3	f661e1737be736c62ffb04a45667a65fc3d11e2a
ToppCell	Control-Control-Myeloid-CD16+_Monocyte\|Control / Disease, condition lineage and cell class	RALB TESC WARS1	3.22e-04	200	30	3	8dd124a5aca897652ea68efbfc5a167b4cf31aef
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Myeloid-Monocytic-Nonclassical_Monocyte\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RALB TESC WARS1	3.22e-04	200	30	3	97f261d56bc6c55683eb4c42670d00b9a6992a26
Drug	Methylatropine nitrate [52-88-0]; Down 200; 11uM; MCF7; HT_HG-U133A	RALB KIAA0930 RRAGD CLEC16A VWA5A	4.86e-06	199	29	5	6495_DN
Drug	Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	NLRP1 KIAA0930 VWA5A GRK5	6.89e-05	175	29	4	4436_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 LMBR1L VWA5A GRK5	7.05e-05	176	29	4	5441_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 TESC VWA5A GRK5	7.20e-05	177	29	4	4710_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 TESC VWA5A GRK5	7.20e-05	177	29	4	6493_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 RRAGD LMBR1L GRK5	7.20e-05	177	29	4	7324_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	NLRP1 KIAA0930 CLEC16A GRK5	7.36e-05	178	29	4	4483_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 RRAGD LMBR1L GRK5	7.36e-05	178	29	4	6454_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 TESC VWA5A GRK5	7.86e-05	181	29	4	5987_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	NLRP1 KIAA0930 LMBR1L GRK5	7.86e-05	181	29	4	6276_UP
Drug	Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A	NLRP1 RRAGD VWA5A GRK5	7.86e-05	181	29	4	4349_UP
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	NLRP1 KIAA0930 VWA5A GRK5	8.02e-05	182	29	4	7043_UP
Drug	Lopac-P-178	NLRP1 RBL2 PLCXD2	8.43e-05	67	29	3	CID005478935
Drug	2-propylpentanoic acid; Up 200; 1000uM; MCF7; HG-U133A	RALA NLRP1 RRAGD GRK5	9.87e-05	192	29	4	23_UP
Drug	Clozapine [5786-21-0]; Up 200; 12.2uM; MCF7; HT_HG-U133A	RRAGD RBL2 PLTP GRK5	1.05e-04	195	29	4	5265_UP
Drug	Cephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A	NLRP1 VWA5A GRK5 ACOX3	1.07e-04	196	29	4	4482_UP
Drug	Isopropamide iodide [71-81-8]; Up 200; 8.4uM; MCF7; HT_HG-U133A	TESC ERCC6 GRK5 TPD52	1.07e-04	196	29	4	6781_UP
Drug	Clorsulon [60200-06-8]; Down 200; 10.6uM; HL60; HG-U133A	RALB ERCC6 VWA5A GRK5	1.07e-04	196	29	4	1735_DN
Drug	Piracetam [7491-74-9]; Down 200; 28.2uM; HL60; HG-U133A	RALB RIOK2 VWA5A GRK5	1.16e-04	200	29	4	1710_DN
Disease	follicular lymphoma (implicated_via_orthology)	RRAGD RRAGC	9.31e-06	5	29	2	DOID:0050873 (implicated_via_orthology)
Disease	candidiasis (implicated_via_orthology)	RRAGD RRAGC	8.60e-04	44	29	2	DOID:1508 (implicated_via_orthology)
Disease	IGFBP-3 measurement	CLEC16A GRK5	1.29e-03	54	29	2	EFO_0004626
Disease	triglycerides in medium VLDL measurement	DNAH10 PLTP	1.34e-03	55	29	2	EFO_0022155
Disease	triglycerides in large VLDL measurement	DNAH10 PLTP	1.39e-03	56	29	2	EFO_0022178
Disease	triglycerides in small VLDL measurement	DNAH10 PLTP	1.65e-03	61	29	2	EFO_0022145
Disease	phospholipids in large VLDL measurement	DNAH10 PLTP	1.70e-03	62	29	2	EFO_0022169
Disease	phospholipids in very large VLDL measurement	DNAH10 PLTP	1.70e-03	62	29	2	EFO_0022299
Disease	total lipids in very large VLDL measurement	DNAH10 PLTP	1.70e-03	62	29	2	EFO_0022313
Disease	cholesterol in very large VLDL measurement	DNAH10 PLTP	1.87e-03	65	29	2	EFO_0022230
Disease	cholesterol in large VLDL measurement	DNAH10 PLTP	1.87e-03	65	29	2	EFO_0021902
Disease	total lipids in small VLDL	DNAH10 PLTP	1.98e-03	67	29	2	EFO_0022148
Disease	total lipids in large VLDL	DNAH10 PLTP	1.98e-03	67	29	2	EFO_0022175
Disease	triglycerides to phosphoglycerides ratio	DNAH10 PLTP	2.04e-03	68	29	2	EFO_0022327
Disease	free cholesterol in large VLDL measurement	DNAH10 PLTP	2.04e-03	68	29	2	EFO_0022265
Disease	mean platelet volume	RALB FRYL TESC GRK5 MCM9	2.91e-03	1020	29	5	EFO_0004584

Protein segments in the cluster

Peptide	Gene	Start	Entry
FEYDFLSVEDMFKSP	ACOX3	86	O15254
TLQFMYDEFVEDYEP	RALA	31	P11233
TLQFMYDEFVEDYEP	RALB	31	P11234
MFEIYSQHFQPDEDF	RBL2	466	Q08999
MKFVPNETYFSFDEF	ERCC6	726	P0DP91
NETYFSFDEFMVPYF	ERCC6	731	P0DP91
PNIFFMIDSFEEVFS	KIAA0930	161	Q6ICG6
ERMVYVAFSEFFFDS	PLTP	261	P55058
FQEFFAAMSYVLEDE	NLRP1	626	Q9C000
VKMYPVEDFEASFQF	FRYL	231	O94915
TFDDDKMEFYPTFQD	DNAH12	331	Q6ZR08
MSYFLDVFLFPQEDL	DNAH12	556	Q6ZR08
MYFFLYEEEFDPFFR	FBXL3	291	Q9UKT7
VVFNFLLMAYFDPDF	SELENOI	61	Q9C0D9
EPFHEYLDSMFFDRF	GRK5	156	P34947
MDEYLGDFIFDTFQP	DNAH10	4106	Q8IVF4
QIDFFDPTFDYEMIF	RRAGD	121	Q9NQL2
FAPYEANVDFEIRFM	POLD1	241	P28340
VMHFFLYEEEFETFF	FBXL21P	296	Q9UKT6
EYFNMFPSEVLTIFD	MCM9	56	Q9NXL9
DFPAFLEAMSEVFEY	RTL1	266	A6NKG5
VFFFSHFNFDVMELP	RTL1	971	A6NKG5
VDVSFMYLTFFLEDD	WARS1	396	P23381
MDFFDPTFDYEMIFR	RRAGC	121	Q9HB90
FLMPFAYFFTESEGF	LMBR1L	126	Q6UX01
DEINFEDFLTIMSYF	TESC	81	Q96BS2
FDFSDEEIMAYYISF	CLEC16A	131	Q2KHT3
EIIFLDFNHFYAMDE	PLCXD2	156	Q0VAA5
FVFPMDEDSAVYSFE	VWA5A	51	O00534
DFFMKRFSYESELFP	RIOK2	271	Q9BVS4
MPEIFFQMYASDAFF	UBE4A	421	Q14139
MDLYEDYQSPFDFDA	TPD52	6	P55327
FTMFFLVAEEPYLFS	TMPPE	101	Q6ZT21