Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	peptide lactyltransferase (CoA-dependent) activity	CREBBP EP300	5.24e-05	2	145	2	GO:0120300
GeneOntologyMolecularFunction	histone H3K27 acetyltransferase activity	CREBBP EP300	5.24e-05	2	145	2	GO:0044017
GeneOntologyMolecularFunction	histone H3K18 acetyltransferase activity	CREBBP EP300	1.56e-04	3	145	2	GO:0043993
GeneOntologyMolecularFunction	histone H3 acetyltransferase activity	JADE2 CREBBP EP300	1.60e-04	15	145	3	GO:0010484
GeneOntologyMolecularFunction	calcium channel activity	CACNA1F STIM2 RYR3 ITPR1 CACNA1I CNGB1	3.61e-04	129	145	6	GO:0005262
GeneOntologyMolecularFunction	calcium ion binding	HSPG2 STIM2 PCDHA8 EFCAB14 DNAH7 RYR3 ITPR1 CAPN13 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3 OC90	3.68e-04	749	145	15	GO:0005509
GeneOntologyMolecularFunction	histone acetyltransferase activity	JADE2 CREBBP ARRB1 EP300	5.11e-04	51	145	4	GO:0004402
GeneOntologyMolecularFunction	peptide-lysine-N-acetyltransferase activity	JADE2 CREBBP ARRB1 EP300	6.82e-04	55	145	4	GO:0061733
GeneOntologyMolecularFunction	calcium ion transmembrane transporter activity	CACNA1F STIM2 RYR3 ITPR1 CACNA1I CNGB1	8.30e-04	151	145	6	GO:0015085
GeneOntologyMolecularFunction	monoatomic cation channel activity	CACNA1F STIM2 RYR3 ITPR1 KCNA4 SCN9A CACNA1I CNGB1 UNC80	9.19e-04	343	145	9	GO:0005261
GeneOntologyMolecularFunction	peptide N-acetyltransferase activity	JADE2 CREBBP ARRB1 EP300	9.49e-04	60	145	4	GO:0034212
GeneOntologyCellularComponent	extracellular matrix	COL4A4 HSPG2 LRRN1 FCN3 SNED1 FBN1 PXDN MEGF6 CCN2 LTBP3 PLG MUC2 SCARA3 OC90	2.09e-04	656	146	14	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	COL4A4 HSPG2 LRRN1 FCN3 SNED1 FBN1 PXDN MEGF6 CCN2 LTBP3 PLG MUC2 SCARA3 OC90	2.15e-04	658	146	14	GO:0030312
GeneOntologyCellularComponent	kinetochore	APC BIRC5 TEX14 NUDCD2 CREBBP SKA1 KIF22	2.87e-04	181	146	7	GO:0000776
GeneOntologyCellularComponent	condensed chromosome, centromeric region	APC BIRC5 TEX14 NUDCD2 CREBBP SKA1 KIF22	4.22e-04	193	146	7	GO:0000779
GeneOntologyCellularComponent	intercellular bridge	TEX14 NUDCD2 NISCH SKA1 PCNT	5.17e-04	94	146	5	GO:0045171
HumanPheno	Elbow dislocation	HSPG2 APC CHD7 CREBBP FBN1 LMX1B FZD2 EP300 KIF22	7.69e-07	84	64	9	HP:0003042
HumanPheno	Abnormality of the elbow	HSPG2 APC CHD7 CREBBP FBN1 LMX1B POP1 RSPO2 LTBP3 HEPHL1 FZD2 EP300 UNC80 KIF22 PCNT	1.32e-06	282	64	15	HP:0009811
HumanPheno	Upper extremity joint dislocation	HSPG2 APC CHD7 CREBBP FBN1 LMX1B FZD2 EP300 KIF22	2.41e-06	96	64	9	HP:0030310
HumanPheno	Aplasia involving bones of the extremities	RAD51 SOX11 HSPG2 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 ITPR1 FBN1 LMX1B POP1 FGD1 RSPO2 LTBP3 HERC2 HEPHL1 FZD2 EP300 UNC80 KIF22 PCNT	6.65e-06	759	64	24	HP:0009825
HumanPheno	Aplasia/hypoplasia involving bones of the extremities	RAD51 SOX11 HSPG2 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 ITPR1 FBN1 LMX1B POP1 FGD1 RSPO2 LTBP3 HERC2 HEPHL1 FZD2 EP300 UNC80 KIF22 PCNT	6.96e-06	761	64	24	HP:0045060
HumanPheno	Abnormal morphology of bones of the lower limbs	RAD51 HSPG2 TRPS1 CHD7 CREBBP PALB2 ITPR1 FBN1 LMX1B POP1 SCN9A LTBP3 HEPHL1 FZD2 EP300 KIF22 PCNT	1.06e-05	422	64	17	HP:0040066
HumanPheno	Aplasia/Hypoplasia of the thumb	RAD51 APC CHD7 CREBBP PALB2 FBN1 RSPO2 FZD2 EP300 PCNT	1.40e-05	150	64	10	HP:0009601
HumanPheno	Keloids	APC CREBBP EP300 NOTCH3	1.49e-05	13	64	4	HP:0010562
HumanPheno	Abnormal femur morphology	RAD51 HSPG2 TRPS1 CHD7 CREBBP PALB2 FBN1 LMX1B POP1 LTBP3 FZD2 EP300 KIF22 PCNT	1.70e-05	304	64	14	HP:0002823
HumanPheno	Aplasia/hypoplasia involving bones of the hand	RAD51 SOX11 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 FGD1 RSPO2 LTBP3 HERC2 FZD2 EP300 UNC80 KIF22 PCNT	1.88e-05	538	64	19	HP:0005927
HumanPheno	Aplasia/hypoplasia of the extremities	RAD51 SOX11 HSPG2 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 ITPR1 FBN1 LMX1B POP1 FGD1 RSPO2 LTBP3 HERC2 HEPHL1 FZD2 EP300 UNC80 KIF22 PCNT	2.21e-05	813	64	24	HP:0009815
HumanPheno	Abnormality of upper limb joint	HSPG2 SEPTIN9 TRPS1 APC CHD7 CREBBP RYR3 ITPR1 FBN1 LMX1B POP1 FGD1 RSPO2 AKT1 CCN2 LTBP3 HEPHL1 FZD2 EP300 UNC80 KIF22 PCNT	2.39e-05	705	64	22	HP:0009810
HumanPheno	Abnormal long bone morphology	RAD51 HSPG2 TRPS1 APC CHD7 LRRK1 CREBBP PALB2 ITPR1 FBN1 LMX1B POP1 SCN9A RSPO2 AKT1 PISD LTBP3 HERC2 HEPHL1 FZD2 EP300 NOTCH3 KIF22 PCNT	2.62e-05	821	64	24	HP:0011314
HumanPheno	Short long bone	RAD51 HSPG2 TRPS1 APC CHD7 PALB2 ITPR1 FBN1 LTBP3 HEPHL1 FZD2 EP300 PCNT	3.06e-05	278	64	13	HP:0003026
HumanPheno	Aplasia/Hypoplasia of fingers	RAD51 SOX11 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 FGD1 RSPO2 FZD2 EP300 PCNT	3.24e-05	366	64	15	HP:0006265
HumanPheno	Abnormality of the thigh	RAD51 HSPG2 TRPS1 CHD7 CREBBP PALB2 FBN1 LMX1B POP1 LTBP3 FZD2 EP300 KIF22 PCNT	3.26e-05	322	64	14	HP:0001439
HumanPheno	Abnormal proximal phalanx morphology of the hand	TRPS1 CREBBP FZD2 EP300 KIF22 PCNT	4.02e-05	52	64	6	HP:0009834
HumanPheno	Aplasia/hypoplasia involving bones of the upper limbs	RAD51 SOX11 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 FGD1 RSPO2 LTBP3 HERC2 FZD2 EP300 UNC80 KIF22 PCNT	4.49e-05	572	64	19	HP:0006496
HumanPheno	Abnormality of the dentition	RAD51 SOX11 HSPG2 WNT10B TRPS1 APC CHD7 CREBBP ITPR1 FBN1 KRT71 LMX1B POP1 FGD1 AKT1 CACNA1I CCN2 LTBP3 HERC2 PLG HEPHL1 FTO FZD2 EP300 NOTCH3 PCNT WDR72	4.71e-05	1030	64	27	HP:0000164
HumanPheno	Dislocated radial head	CHD7 CREBBP LMX1B FZD2 EP300 KIF22	5.00e-05	54	64	6	HP:0003083
HumanPheno	Abnormality of the radial head	CHD7 CREBBP LMX1B FZD2 EP300 KIF22	6.82e-05	57	64	6	HP:0003995
HumanPheno	Abnormal femoral epiphysis morphology	HSPG2 TRPS1 CREBBP FZD2 EP300 KIF22 PCNT	8.71e-05	86	64	7	HP:0006499
HumanPheno	Full cheeks	SOX11 HSPG2 PSPH CREBBP FBN1 LMX1B LTBP3 EP300 PCNT	9.52e-05	151	64	9	HP:0000293
HumanPheno	Abnormality of the humeroradial joint	CHD7 CREBBP LMX1B FZD2 EP300 KIF22	1.10e-04	62	64	6	HP:0100744
HumanPheno	Narrow mouth	HSPG2 SEPTIN9 APC CHD7 CREBBP FBN1 LMX1B RSPO2 AKT1 LTBP3 EP300	1.30e-04	234	64	11	HP:0000160
HumanPheno	Abnormal femoral head morphology	TRPS1 CREBBP POP1 FZD2 EP300 KIF22 PCNT	1.34e-04	92	64	7	HP:0003368
HumanPheno	Abnormal metatarsal morphology	HSPG2 TRPS1 ITPR1 FBN1 FGD1 AKT1 HEPHL1 EP300 KIF22	1.42e-04	159	64	9	HP:0001832
HumanPheno	Pilomatrixoma	APC CREBBP EP300	1.51e-04	9	64	3	HP:0030434
HumanPheno	Abnormal lower limb epiphysis morphology	HSPG2 TRPS1 CREBBP FZD2 EP300 KIF22 PCNT	1.53e-04	94	64	7	HP:0006500
HumanPheno	Aortic isthmus hypoplasia	CREBBP EP300	1.55e-04	2	64	2	HP:0034227
HumanPheno	Plantar crease between first and second toes	CREBBP EP300	1.55e-04	2	64	2	HP:0008107
HumanPheno	Fifth metacarpal with ulnar notch	FBN1 LTBP3	1.55e-04	2	64	2	HP:0005900
HumanPheno	High axial triradius	CREBBP EP300	1.55e-04	2	64	2	HP:0001042
HumanPheno	Abnormal cheek morphology	SOX11 HSPG2 CHD7 PSPH CREBBP ZNF462 FBN1 LMX1B FGD1 LTBP3 EP300 PCNT	1.61e-04	282	64	12	HP:0004426
HumanPheno	Clinodactyly	RAD51 SOX11 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 HERC2 HEPHL1 FZD2 EP300 EPB41L1 PCNT	1.61e-04	574	64	18	HP:0030084
HumanPheno	Short thumb	APC CHD7 CREBBP PALB2 FBN1 FZD2 EP300 PCNT	1.64e-04	127	64	8	HP:0009778
HumanPheno	Juvenile aseptic necrosis	TRPS1 CREBBP LMX1B FZD2 EP300	1.78e-04	43	64	5	HP:0100323
HumanPheno	Abnormal lower limb bone morphology	RAD51 HSPG2 WNT10B TRPS1 APC CHD7 CREBBP PALB2 ITPR1 FBN1 LMX1B POP1 SCN9A FGD1 AKT1 LTBP3 HERC2 HEPHL1 FZD2 EP300 EPB41L1 KIF22 PCNT	1.93e-04	866	64	23	HP:0040069
HumanPheno	Sleep-related breathing disorders	CREBBP ZNF462 CACNA1I LTBP3 HERC2 HEPHL1 EP300 UNC80 NOTCH3	2.25e-04	169	64	9	HP:5200283
HumanPheno	Abnormal upper limb bone morphology	RAD51 TRPS1 APC CHD7 CREBBP PALB2 FBN1 LMX1B SCN9A RSPO2 AKT1 LTBP3 FZD2 EP300 KIF22 PCNT	2.25e-04	484	64	16	HP:0040070
HumanPheno	Abnormal morphology of bones of the upper limbs	RAD51 TRPS1 APC CHD7 CREBBP PALB2 FBN1 LMX1B RSPO2 AKT1 LTBP3 FZD2 EP300 KIF22 PCNT	2.40e-04	436	64	15	HP:0040065
HumanPheno	Abnormal midface morphology	SOX11 HSPG2 APC TSEN54 CHD7 PSPH CREBBP ZNF462 FBN1 LMX1B POP1 FGD1 AKT1 LTBP3 FZD2 EP300 EPB41L1 NOTCH3 KIF22 PCNT	2.45e-04	704	64	20	HP:0000309
HumanPheno	Joint dislocation	RAD51 HSPG2 TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 LMX1B AKT1 FZD2 EP300 KIF22	2.60e-04	390	64	14	HP:0001373
HumanPheno	Aplasia/Hypoplasia involving bones of the feet	HSPG2 WNT10B TRPS1 APC CHD7 ITPR1 FBN1 FGD1 LTBP3 HERC2 HEPHL1 EP300	2.70e-04	298	64	12	HP:0006494
HumanPheno	Abnormal hip bone morphology	RAD51 HSPG2 TRPS1 APC CREBBP PALB2 RYR3 FBN1 LMX1B POP1 SCN9A AKT1 CCN2 HERC2 FZD2 EP300 UNC80 KIF22 PCNT	2.71e-04	653	64	19	HP:0003272
HumanPheno	Deep philtrum	HSPG2 TRPS1 CREBBP ITPR1 FBN1 EP300	3.17e-04	75	64	6	HP:0002002
HumanPheno	Abnormal hand morphology	RAD51 SOX11 HSPG2 AFF2 WNT10B TRPS1 APC CHD7 CREBBP PALB2 RYR3 ZNF462 FBN1 LMX1B SCN9A FGD1 RSPO2 AKT1 LTBP3 HERC2 FZD2 EP300 UNC80 EPB41L1 KIF22 PCNT	3.20e-04	1082	64	26	HP:0005922
HumanPheno	Abnormal morphology of the radius	RAD51 APC CHD7 CREBBP PALB2 LMX1B FZD2 EP300 KIF22 PCNT	3.21e-04	217	64	10	HP:0002818
HumanPheno	Radial deviation of finger	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 HERC2 FZD2 EP300 PCNT	3.23e-04	448	64	15	HP:0009466
HumanPheno	Finger clinodactyly	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 FZD2 EP300 EPB41L1 PCNT	3.56e-04	452	64	15	HP:0040019
HumanPheno	Abnormal scrotum morphology	CHD7 CREBBP LMX1B FGD1 AKT1 HERC2 FZD2 EP300	3.71e-04	143	64	8	HP:0000045
HumanPheno	Brachydactyly	SOX11 HSPG2 TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 POP1 FGD1 AKT1 LTBP3 FTO FZD2 EP300 EPB41L1 KIF22 PCNT	3.79e-04	670	64	19	HP:0001156
HumanPheno	Radial deviation of the hand or of fingers of the hand	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 HERC2 FZD2 EP300 PCNT	3.91e-04	456	64	15	HP:0009485
HumanPheno	Short digit	SOX11 HSPG2 TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 POP1 FGD1 AKT1 LTBP3 FTO FZD2 EP300 EPB41L1 KIF22 PCNT	3.94e-04	672	64	19	HP:0011927
HumanPheno	Abnormal pelvic girdle bone morphology	RAD51 HSPG2 TRPS1 APC CREBBP PALB2 RYR3 FBN1 LMX1B POP1 SCN9A RSPO2 AKT1 CCN2 HERC2 FZD2 EP300 UNC80 KIF22 PCNT	4.00e-04	730	64	20	HP:0002644
HumanPheno	Abnormality of the helix	HSPG2 AFF2 CHD7 CPOX CREBBP ZNF462 FBN1 FZD2 EP300	4.09e-04	183	64	9	HP:0000380
HumanPheno	Deviation of the hand or of fingers of the hand	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 RYR3 ZNF462 LMX1B FGD1 AKT1 HERC2 FZD2 EP300 EPB41L1 PCNT	4.16e-04	564	64	17	HP:0009484
HumanPheno	Laryngeal cartilage malformation	CREBBP EP300	4.62e-04	3	64	2	HP:0008752
HumanPheno	Phobia	CREBBP EP300	4.62e-04	3	64	2	HP:5200232
HumanPheno	Agoraphobia	CREBBP EP300	4.62e-04	3	64	2	HP:0000756
HumanPheno	Abnormal upper to lower segment ratio	FBN1 FGD1	4.62e-04	3	64	2	HP:0012772
HumanPheno	Radial deviation of thumb terminal phalanx	CREBBP EP300	4.62e-04	3	64	2	HP:0005895
HumanPheno	Humoral immunodeficiency	CREBBP EP300	4.62e-04	3	64	2	HP:0005363
HumanPheno	Prominent nasal septum	CREBBP EP300	4.62e-04	3	64	2	HP:0005322
HumanPheno	Avascular necrosis of the capital femoral epiphysis	TRPS1 CREBBP FZD2 EP300	4.86e-04	30	64	4	HP:0005743
HumanPheno	Abnormality of the tubular bones	RAD51 HSPG2 TRPS1 APC CHD7 CREBBP PALB2 ITPR1 FBN1 RSPO2 AKT1 LTBP3 HERC2 HEPHL1 FZD2 EP300 KIF22 PCNT	5.40e-04	632	64	18	HP:0100713
HumanPheno	Abnormality of the long tubular bones	RAD51 HSPG2 TRPS1 APC CHD7 CREBBP PALB2 ITPR1 FBN1 RSPO2 AKT1 LTBP3 HERC2 HEPHL1 FZD2 EP300 KIF22 PCNT	5.40e-04	632	64	18	HP:0100714
HumanPheno	Abnormality of the epiphysis of the femoral head	TRPS1 CREBBP FZD2 EP300 KIF22 PCNT	5.50e-04	83	64	6	HP:0010574
HumanPheno	Clinodactyly of the 5th finger	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 FZD2 EP300 PCNT	5.57e-04	420	64	14	HP:0004209
HumanPheno	Clinodactyly of hands	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 FZD2 EP300 PCNT	5.71e-04	421	64	14	HP:0001157
HumanPheno	Deviation of the 5th finger	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 FZD2 EP300 PCNT	5.71e-04	421	64	14	HP:0009179
HumanPheno	Abnormal number of teeth	RAD51 HSPG2 WNT10B TRPS1 APC CHD7 CREBBP POP1 FGD1 AKT1 LTBP3 FZD2 EP300 PCNT	5.71e-04	421	64	14	HP:0006483
HumanPheno	Laryngomalacia	HSPG2 APC CHD7 CREBBP EP300 PCNT	5.86e-04	84	64	6	HP:0001601
HumanPheno	Aplasia/hypoplasia involving bones of the lower limbs	HSPG2 WNT10B TRPS1 APC CHD7 ITPR1 FBN1 LMX1B POP1 FGD1 LTBP3 HERC2 HEPHL1 FZD2 EP300	5.93e-04	474	64	15	HP:0006493
HumanPheno	Short finger	SOX11 TRPS1 APC CHD7 CREBBP PALB2 RYR3 FBN1 FGD1 FZD2 EP300 PCNT	5.98e-04	325	64	12	HP:0009381
HumanPheno	Abnormal epiphysis morphology	HSPG2 TRPS1 CREBBP FBN1 SCN9A PISD LTBP3 FZD2 EP300 KIF22 PCNT	6.02e-04	279	64	11	HP:0005930
HumanPheno	Congenital malformation of the great arteries	RAD51 SOX11 HSPG2 CHD7 CREBBP PALB2 ITPR1 ZNF462 RSPH3 FBN1 LMX1B CFAP74 FTO EP300 NOTCH3 PCNT	6.20e-04	529	64	16	HP:0011603
HumanPheno	Supernumerary tooth	HSPG2 TRPS1 APC CREBBP FZD2 EP300	6.25e-04	85	64	6	HP:0011069
HumanPheno	Abnormal forearm bone morphology	RAD51 APC CHD7 CREBBP PALB2 LMX1B FZD2 EP300 KIF22 PCNT	6.27e-04	236	64	10	HP:0040072
HumanPheno	Abnormal forearm morphology	RAD51 APC CHD7 CREBBP PALB2 LMX1B FZD2 EP300 KIF22 PCNT	6.92e-04	239	64	10	HP:0002973
HumanPheno	Hypoplastic facial bones	HSPG2 APC CHD7 CREBBP FBN1 FGD1 AKT1 LTBP3 FZD2 EP300 NOTCH3 KIF22	7.05e-04	331	64	12	HP:0002692
HumanPheno	Aplasia/Hypoplasia of facial bones	HSPG2 APC CHD7 CREBBP FBN1 FGD1 AKT1 LTBP3 FZD2 EP300 NOTCH3 KIF22	7.24e-04	332	64	12	HP:0034261
HumanPheno	Deviation of finger	RAD51 HSPG2 AFF2 TRPS1 CHD7 CREBBP PALB2 ZNF462 LMX1B FGD1 AKT1 HERC2 FZD2 EP300 EPB41L1 PCNT	7.32e-04	537	64	16	HP:0004097
HumanPheno	Abnormal larynx morphology	HSPG2 APC CHD7 CREBBP LTBP3 PLG EP300 KIF22 PCNT	8.10e-04	201	64	9	HP:0025423
HumanPheno	Abnormal femoral neck/head morphology	HSPG2 TRPS1 CREBBP LMX1B POP1 FZD2 EP300 KIF22 PCNT	8.10e-04	201	64	9	HP:0003366
HumanPheno	Abnormal hip joint morphology	RAD51 HSPG2 TRPS1 APC CREBBP PALB2 RYR3 FBN1 AKT1 HERC2 FZD2 EP300 UNC80 KIF22 PCNT	8.42e-04	490	64	15	HP:0001384
HumanPheno	Trichiasis	CREBBP EP300	9.17e-04	4	64	2	HP:0001128
HumanPheno	Visceral hemangioma	CREBBP EP300	9.17e-04	4	64	2	HP:0410266
HumanPheno	Widened distal phalanges	CREBBP EP300	9.17e-04	4	64	2	HP:0006200
HumanPheno	Hepatic hemangioma	CREBBP EP300	9.17e-04	4	64	2	HP:0031207
HumanPheno	Talipes calcaneovarus	FBN1 LMX1B	9.17e-04	4	64	2	HP:0008124
HumanPheno	Talon cusp	CREBBP EP300	9.17e-04	4	64	2	HP:0011087
HumanPheno	Vascular ring	CREBBP EP300	9.17e-04	4	64	2	HP:0010775
HumanPheno	Abnormal facial shape	RAD51 SOX11 HSPG2 SEPTIN9 WNT10B TRPS1 APC TSEN54 CHD7 PSPH CREBBP PALB2 RYR3 ITPR1 FBN1 LMX1B FGD1 AKT1 LTBP3 HEPHL1 FTO FZD2 EP300 UNC80 NOTCH3 KIF22 PCNT	9.25e-04	1221	64	27	HP:0001999
HumanPheno	Square face	CHD7 CREBBP EP300	9.43e-04	16	64	3	HP:0000321
HumanPheno	Short metatarsal	TRPS1 ITPR1 FBN1 HEPHL1 EP300	9.96e-04	62	64	5	HP:0010743
HumanPheno	Long eyelashes	SOX11 HSPG2 CREBBP FBN1 LTBP3 FZD2 EP300	1.06e-03	129	64	7	HP:0000527
HumanPheno	Hypoplastic ilia	HSPG2 CREBBP POP1 EP300 PCNT	1.07e-03	63	64	5	HP:0000946
HumanPheno	Sleep apnea	CREBBP ZNF462 CACNA1I LTBP3 HERC2 EP300 UNC80 NOTCH3	1.08e-03	168	64	8	HP:0010535
HumanPheno	Limited elbow movement	FBN1 LMX1B RSPO2 LTBP3 FZD2 UNC80 KIF22 PCNT	1.08e-03	168	64	8	HP:0002996
MousePheno	abnormal chest morphology	SOX11 HSPG2 ITPK1 FBN1 CCN2	1.73e-05	39	117	5	MP:0004134
MousePheno	abnormal maxilla morphology	SOX11 TRPS1 LRRK1 PSPH CREBBP NISCH RSPO2 LTBP3	2.76e-05	144	117	8	MP:0000455
MousePheno	abnormal uvea morphology	CD46 CHD7 GRM6 ITPR1 PXDN ABHD17B LMX1B LTBP3 PLG EPB41L1	3.42e-05	241	117	10	MP:0005197
MousePheno	absence of all nails	LMX1B RSPO2	6.95e-05	2	117	2	MP:0008494
MousePheno	impaired long-term object recognition memory	FOXO6 JADE2 CREBBP DCAF11	8.17e-05	28	117	4	MP:0014367
MousePheno	abnormal pelvic girdle bone morphology	HSPG2 LRRK1 PSPH FBN1 LMX1B PAPPA	8.79e-05	87	117	6	MP:0004509
Domain	ZF_ZZ_2	CREBBP HERC2 NBR1 EP300	8.29e-06	18	139	4	PS50135
Domain	ZF_ZZ_1	CREBBP HERC2 NBR1 EP300	8.29e-06	18	139	4	PS01357
Domain	ZZ	CREBBP HERC2 NBR1 EP300	8.29e-06	18	139	4	PF00569
Domain	Znf_ZZ	CREBBP HERC2 NBR1 EP300	1.04e-05	19	139	4	IPR000433
Domain	ZnF_ZZ	CREBBP HERC2 NBR1 EP300	1.04e-05	19	139	4	SM00291
Domain	Growth_fac_rcpt_	HSPG2 FBN1 EGF MEGF6 RSPO2 CCN2 LTBP3 NOTCH3	2.21e-05	156	139	8	IPR009030
Domain	Ion_trans_dom	CACNA1F RYR3 ITPR1 KCNA4 SCN9A CACNA1I CNGB1	2.30e-05	114	139	7	IPR005821
Domain	Ion_trans	CACNA1F RYR3 ITPR1 KCNA4 SCN9A CACNA1I CNGB1	2.30e-05	114	139	7	PF00520
Domain	EGF_CA	HSPG2 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	3.57e-05	122	139	7	SM00179
Domain	EGF-like_Ca-bd_dom	HSPG2 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	3.96e-05	124	139	7	IPR001881
Domain	hEGF	SNED1 MEGF6 LTBP3 NOTCH3	5.24e-05	28	139	4	PF12661
Domain	Nuc_rcpt_coact_CREBbp	CREBBP EP300	5.50e-05	2	139	2	IPR014744
Domain	ZnF_TAZ	CREBBP EP300	5.50e-05	2	139	2	SM00551
Domain	-	CREBBP EP300	5.50e-05	2	139	2	1.20.1020.10
Domain	RING_CBP-p300	CREBBP EP300	5.50e-05	2	139	2	IPR010303
Domain	-	CREBBP EP300	5.50e-05	2	139	2	1.10.1630.10
Domain	Creb_binding	CREBBP EP300	5.50e-05	2	139	2	PF09030
Domain	zf-TAZ	CREBBP EP300	5.50e-05	2	139	2	PF02135
Domain	ZF_TAZ	CREBBP EP300	5.50e-05	2	139	2	PS50134
Domain	KAT11	CREBBP EP300	5.50e-05	2	139	2	SM01250
Domain	Znf_TAZ	CREBBP EP300	5.50e-05	2	139	2	IPR000197
Domain	KIX	CREBBP EP300	5.50e-05	2	139	2	PF02172
Domain	HAT_KAT11	CREBBP EP300	5.50e-05	2	139	2	PF08214
Domain	KIX	CREBBP EP300	5.50e-05	2	139	2	PS50952
Domain	CBP_P300_HAT	CREBBP EP300	5.50e-05	2	139	2	IPR031162
Domain	DUF902	CREBBP EP300	5.50e-05	2	139	2	PF06001
Domain	-	CREBBP EP300	5.50e-05	2	139	2	1.10.246.20
Domain	Histone_AcTrfase_Rtt109/CBP	CREBBP EP300	5.50e-05	2	139	2	IPR013178
Domain	KIX_dom	CREBBP EP300	5.50e-05	2	139	2	IPR003101
Domain	CBP_P300_HAT	CREBBP EP300	5.50e-05	2	139	2	PS51727
Domain	EGF_Ca-bd_CS	SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	8.65e-05	97	139	6	IPR018097
Domain	EGF_CA	SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	9.69e-05	99	139	6	PS01187
Domain	ASX_HYDROXYL	SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	1.02e-04	100	139	6	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	1.41e-04	106	139	6	IPR000152
Domain	EGF_3	HSPG2 ADAM20 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	3.82e-04	235	139	8	PS50026
Domain	EGF_CA	FBN1 EGF MEGF6 LTBP3 NOTCH3	4.56e-04	86	139	5	PF07645
Domain	EGF-like_dom	HSPG2 ADAM20 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	5.60e-04	249	139	8	IPR000742
Domain	EGF_1	HSPG2 ADAM20 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	6.54e-04	255	139	8	PS00022
Domain	EGF-like_CS	HSPG2 ADAM20 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	7.62e-04	261	139	8	IPR013032
Domain	RIH_assoc-dom	RYR3 ITPR1	8.09e-04	6	139	2	IPR013662
Domain	Nuc_rcpt_coact	CREBBP EP300	8.09e-04	6	139	2	IPR009110
Domain	Ins145_P3_rec	RYR3 ITPR1	8.09e-04	6	139	2	PF08709
Domain	PEROXIDASE_1	MPO PXDN	8.09e-04	6	139	2	PS00435
Domain	RIH_assoc	RYR3 ITPR1	8.09e-04	6	139	2	PF08454
Domain	RIH_dom	RYR3 ITPR1	8.09e-04	6	139	2	IPR000699
Domain	Ins145_P3_rcpt	RYR3 ITPR1	8.09e-04	6	139	2	IPR014821
Domain	Ryanodine_recept-rel	RYR3 ITPR1	8.09e-04	6	139	2	IPR015925
Domain	-	RYR3 ITPR1	8.09e-04	6	139	2	1.25.10.30
Domain	RYDR_ITPR	RYR3 ITPR1	8.09e-04	6	139	2	PF01365
Domain	EGF_2	HSPG2 ADAM20 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	8.40e-04	265	139	8	PS01186
Domain	Channel_four-helix_dom	CACNA1F KCNA4 SCN9A CACNA1I	8.55e-04	57	139	4	IPR027359
Domain	-	CACNA1F KCNA4 SCN9A CACNA1I	8.55e-04	57	139	4	1.20.120.350
Domain	TB	FBN1 LTBP3	1.13e-03	7	139	2	PF00683
Domain	Notch_dom	PAPPA NOTCH3	1.13e-03	7	139	2	IPR000800
Domain	Notch	PAPPA NOTCH3	1.13e-03	7	139	2	PF00066
Domain	Hlx-hairpin-Hlx_DNA-bd_motif	RAD51 KIF22	1.13e-03	7	139	2	IPR003583
Domain	HhH1	RAD51 KIF22	1.13e-03	7	139	2	SM00278
Domain	NL	PAPPA NOTCH3	1.13e-03	7	139	2	SM00004
Domain	-	FBN1 LTBP3	1.50e-03	8	139	2	3.90.290.10
Domain	EGF	HSPG2 SNED1 FBN1 EGF MEGF6 LTBP3 NOTCH3	1.91e-03	235	139	7	SM00181
Domain	TB_dom	FBN1 LTBP3	1.91e-03	9	139	2	IPR017878
Domain	TB	FBN1 LTBP3	1.91e-03	9	139	2	PS51364
Domain	MIR	RYR3 ITPR1	2.38e-03	10	139	2	PF02815
Domain	An_peroxidase	MPO PXDN	2.38e-03	10	139	2	PF03098
Domain	MIR_motif	RYR3 ITPR1	2.38e-03	10	139	2	IPR016093
Domain	Haem_peroxidase_animal	MPO PXDN	2.38e-03	10	139	2	IPR019791
Domain	MIR	RYR3 ITPR1	2.38e-03	10	139	2	PS50919
Domain	MIR	RYR3 ITPR1	2.38e-03	10	139	2	SM00472
Domain	Haem_peroxidase	MPO PXDN	2.38e-03	10	139	2	IPR010255
Domain	PEROXIDASE_3	MPO PXDN	2.38e-03	10	139	2	PS50292
Domain	VDCCAlpha1	CACNA1F CACNA1I	2.38e-03	10	139	2	IPR002077
Domain	-	MPO PXDN	2.38e-03	10	139	2	1.10.640.10
Domain	VWFC_1	PXDN CCN2 MUC2	2.41e-03	36	139	3	PS01208
Domain	EGF	HSPG2 SNED1 EGF MEGF6 NOTCH3	2.53e-03	126	139	5	PF00008
Domain	VWFC_2	PXDN CCN2 MUC2	2.81e-03	38	139	3	PS50184
Domain	VWC	PXDN CCN2 MUC2	2.81e-03	38	139	3	SM00214
Domain	Ig_I-set	HSPG2 LRRN1 NCAM2 PXDN CD22 ALPK2	3.01e-03	190	139	6	IPR013098
Domain	I-set	HSPG2 LRRN1 NCAM2 PXDN CD22 ALPK2	3.01e-03	190	139	6	PF07679
Domain	VWF_dom	PXDN CCN2 MUC2	3.75e-03	42	139	3	IPR001007
Domain	SAM	STIM2 PPFIBP2 SHANK2 BICC1	4.23e-03	88	139	4	SM00454
Domain	IBR	RNF31 ANKIB1	4.72e-03	14	139	2	PF01485
Domain	IBR	RNF31 ANKIB1	4.72e-03	14	139	2	SM00647
Domain	IBR_dom	RNF31 ANKIB1	5.42e-03	15	139	2	IPR002867
Domain	SAM_DOMAIN	STIM2 PPFIBP2 SHANK2 BICC1	5.54e-03	95	139	4	PS50105
Domain	SAM	STIM2 PPFIBP2 SHANK2 BICC1	5.97e-03	97	139	4	IPR001660
Domain	SANT	GON4L CHD7 TERF1	6.12e-03	50	139	3	SM00717
Domain	SANT/Myb	GON4L CHD7 TERF1	6.83e-03	52	139	3	IPR001005
Pathway	BIOCARTA_PELP1_PATHWAY	CREBBP PELP1 EP300	1.04e-05	6	115	3	M22062
Pathway	KEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA	FBN1 LTBP3 PLG	2.87e-05	8	115	3	M47850
Pathway	REACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES	CREBBP EGF EP300	8.32e-05	11	115	3	M48021
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SPTLC3 ZNF609 LRRN1 JADE2 PPFIBP2 SEPTIN9 TRPS1 NCAM2 STK32C CREBBP ITPK1 ZNF462 ARRB1 PXDN SHANK2 MEGF6 ZNF608 MICAL2 ANKIB1 PISD SCARA3 NBR1 EP300 EPB41L1 NOTCH3 PCNT	8.91e-10	1489	148	26	28611215
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	JADE2 TRPS1 APBA1 DEF8 NAP1L1 APC WHAMM NCAM2 TERF1 CREBBP BFSP1 RYR3 ARRB1 FBN1 MICAL2 NISCH CCN2 LTBP3 HERC2 MAP4K4 EP300 PCNT	2.91e-08	1285	148	22	35914814
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RAD51 MPP3 HSPG2 LRRK1 STK32C ZDHHC8 SHANK2 MEGF6 LMX1B NISCH PDCD11 AKT1 WDR90 LTBP3 HERC2 SCARA3 ADAT1 EP300 PCNT SYMPK	5.39e-08	1105	148	20	35748872
Pubmed	Cutting edge: abortive proliferation of CD46-induced Tr1-like cells due to a defective Akt/Survivin signaling pathway.	BIRC5 CD46 AKT1	7.55e-08	3	148	3	17015676
Pubmed	A human MAP kinase interactome.	JADE2 APC STK32C TERF1 CREBBP PPP4R3A ARRB1 TNRC6A NKTR HERC2 MAP3K21 MAP4K4 EP300	1.82e-07	486	148	13	20936779
Pubmed	Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor alpha.	CREBBP PELP1 EP300	3.01e-07	4	148	3	11481323
Pubmed	CBP and p300 histone acetyltransferases contribute to homologous recombination by transcriptionally activating the BRCA1 and RAD51 genes.	RAD51 CREBBP EP300	3.01e-07	4	148	3	23285190
Pubmed	Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro.	NAP1L1 CREBBP EP300	3.01e-07	4	148	3	11940655
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	MPO HSPG2 ZSCAN5DP TRPS1 DEF8 BIRC5 CHD7 ITPR1 POP1 FGD1 EP300	4.92e-07	363	148	11	14691545
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	ZDHHC18 SEPTIN9 NAP1L1 CHD7 ITPK1 ITPR1 ZNF462 TNRC6A FTO MAP4K4 NBR1 EPB41L1 SYMPK	5.51e-07	536	148	13	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	ZDHHC18 SEPTIN9 NAP1L1 CHD7 ITPK1 ITPR1 ZNF462 TNRC6A FTO MAP4K4 NBR1 EPB41L1 SYMPK	5.74e-07	538	148	13	10512203
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAD51 ZNF609 TRPS1 APC CHD7 NUDCD2 PALB2 ZNF462 ZNF608 TNRC6A PCNT	1.94e-06	418	148	11	34709266
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	ZNF609 PPFIBP2 APC RBSN SHANK2 ABHD17B TNRC6A FGD1 HERC2 FZD2 MAP4K4 NBR1 EPB41L1 WDR72	2.64e-06	719	148	14	35337019
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZNF609 JADE2 LRRK1 MAST4 ZNF608 TNRC6A ANKIB1 PDCD11 WDR90 FTO MAP4K4 NBR1	3.04e-06	529	148	12	14621295
Pubmed	Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.	APC AKT1 PCNT	4.16e-06	8	148	3	29170395
Pubmed	LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.	SEPTIN9 BFSP1 RYR3 SNED1 ARRB1 MICAL2 NOTCH3	8.17e-06	168	148	7	30631154
Pubmed	Loss of p300 accelerates MDS-associated leukemogenesis.	CREBBP EP300	1.80e-05	2	148	2	27881875
Pubmed	Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.	CREBBP EP300	1.80e-05	2	148	2	34845315
Pubmed	Genetic analysis of the contribution of LTBP-3 to thoracic aneurysm in Marfan syndrome.	FBN1 LTBP3	1.80e-05	2	148	2	26494287
Pubmed	Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.	CREBBP EP300	1.80e-05	2	148	2	20717166
Pubmed	The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.	CREBBP EP300	1.80e-05	2	148	2	25893291
Pubmed	Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.	CREBBP EP300	1.80e-05	2	148	2	11559821
Pubmed	The immunomodulator AS101 induces growth arrest and apoptosis in multiple myeloma: association with the Akt/survivin pathway.	BIRC5 AKT1	1.80e-05	2	148	2	16889755
Pubmed	Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.	CREBBP EP300	1.80e-05	2	148	2	19822209
Pubmed	CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.	CREBBP EP300	1.80e-05	2	148	2	21847097
Pubmed	Role of Akt/protein kinase B in the activity of transcriptional coactivator p300.	AKT1 EP300	1.80e-05	2	148	2	15224190
Pubmed	Beta-HPV 5 and 8 E6 promote p300 degradation by blocking AKT/p300 association.	AKT1 EP300	1.80e-05	2	148	2	21901101
Pubmed	p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.	CREBBP EP300	1.80e-05	2	148	2	34813504
Pubmed	Rubinstein-Taybi Syndrome	CREBBP EP300	1.80e-05	2	148	2	20301699
Pubmed	Fibronectin protects prostate cancer cells from tumor necrosis factor-alpha-induced apoptosis via the AKT/survivin pathway.	BIRC5 AKT1	1.80e-05	2	148	2	14523021
Pubmed	Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.	CREBBP EP300	1.80e-05	2	148	2	35502657
Pubmed	p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.	CREBBP EP300	1.80e-05	2	148	2	31898871
Pubmed	Sodium valproate potentiates staurosporine-induced apoptosis in neuroblastoma cells via Akt/survivin independently of HDAC inhibition.	BIRC5 AKT1	1.80e-05	2	148	2	23097134
Pubmed	Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.	CREBBP EP300	1.80e-05	2	148	2	30888860
Pubmed	Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.	CREBBP EP300	1.80e-05	2	148	2	27881443
Pubmed	Functional communication between IP3R and STIM2 at subthreshold stimuli is a critical checkpoint for initiation of SOCE.	STIM2 ITPR1	1.80e-05	2	148	2	35022238
Pubmed	Absence of LTBP-3 attenuates the aneurysmal phenotype but not spinal effects on the aorta in Marfan syndrome.	FBN1 LTBP3	1.80e-05	2	148	2	30306291
Pubmed	CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.	CREBBP EP300	1.80e-05	2	148	2	30953353
Pubmed	Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.	CREBBP EP300	1.80e-05	2	148	2	21803292
Pubmed	HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.	CREBBP EP300	1.80e-05	2	148	2	9811832
Pubmed	Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.	CREBBP EP300	1.80e-05	2	148	2	24089570
Pubmed	Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.	CREBBP EP300	1.80e-05	2	148	2	15706485
Pubmed	AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.	CREBBP EP300	1.80e-05	2	148	2	39266679
Pubmed	A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.	CREBBP EP300	1.80e-05	2	148	2	22303793
Pubmed	Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B-mediated phosphorylation and cytoplasmic translocation of p27(Kip-1).	AKT1 CCN2	1.80e-05	2	148	2	16790529
Pubmed	Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.	CREBBP EP300	1.80e-05	2	148	2	34732714
Pubmed	Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.	CREBBP EP300	1.80e-05	2	148	2	34019788
Pubmed	Microfibrils at basement membrane zones interact with perlecan via fibrillin-1.	HSPG2 FBN1	1.80e-05	2	148	2	15657057
Pubmed	Lipopolysaccharide induces VCAM-1 expression and neutrophil adhesion to human tracheal smooth muscle cells: involvement of Src/EGFR/PI3-K/Akt pathway.	AKT1 EP300	1.80e-05	2	148	2	18182168
Pubmed	The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.	CREBBP EP300	1.80e-05	2	148	2	9018065
Pubmed	Winnie-APCMin/+ Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation.	APC MUC2	1.80e-05	2	148	2	32340123
Pubmed	Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.	APC MUC2	1.80e-05	2	148	2	18794118
Pubmed	LTBP3 Pathogenic Variants Predispose Individuals to Thoracic Aortic Aneurysms and Dissections.	FBN1 LTBP3	1.80e-05	2	148	2	29625025
Pubmed	Functional expression of the voltage-gated Na⁺-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells.	EGF SCN9A	1.80e-05	2	148	2	23986482
Pubmed	Enhanced Notch3 signaling contributes to pulmonary emphysema in a Murine Model of Marfan syndrome.	FBN1 NOTCH3	1.80e-05	2	148	2	32616814
Pubmed	CBP/p300 acetyltransferase activity in hematologic malignancies.	CREBBP EP300	1.80e-05	2	148	2	27380996
Pubmed	CREBBP and p300 lysine acetyl transferases in the DNA damage response.	CREBBP EP300	1.80e-05	2	148	2	29170789
Pubmed	Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.	CREBBP EP300	1.80e-05	2	148	2	21555743
Pubmed	CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.	CREBBP EP300	1.80e-05	2	148	2	12646247
Pubmed	Insulin suppresses transactivation by CAAT/enhancer-binding proteins beta (C/EBPbeta). Signaling to p300/CREB-binding protein by protein kinase B disrupts interaction with the major activation domain of C/EBPbeta.	AKT1 EP300	1.80e-05	2	148	2	11116148
Pubmed	Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.	CREBBP EP300	1.80e-05	2	148	2	11867645
Pubmed	Progesterone potentiates calcium release through IP3 receptors by an Akt-mediated mechanism in hippocampal neurons.	ITPR1 AKT1	1.80e-05	2	148	2	19081133
Pubmed	Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.	CREBBP EP300	1.80e-05	2	148	2	11963968
Pubmed	PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.	APC MUC2	1.80e-05	2	148	2	19232344
Pubmed	Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.	CREBBP EP300	1.80e-05	2	148	2	12242694
Pubmed	Upregulation of FoxO6 in nucleus pulposus cells promotes DNA damage repair via activation of RAD51.	RAD51 FOXO6	1.80e-05	2	148	2	34533813
Pubmed	Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice.	APC TNS4	1.80e-05	2	148	2	32567731
Pubmed	CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.	CREBBP EP300	1.80e-05	2	148	2	31182547
Pubmed	Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.	CREBBP EP300	1.80e-05	2	148	2	27648933
Pubmed	Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.	CREBBP EP300	1.80e-05	2	148	2	10610021
Pubmed	CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.	CREBBP EP300	1.80e-05	2	148	2	15641773
Pubmed	Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.	CREBBP EP300	1.80e-05	2	148	2	9733868
Pubmed	Is HSPG2 a modifier gene for Marfan syndrome?	HSPG2 FBN1	1.80e-05	2	148	2	32514132
Pubmed	EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.	CREBBP EP300	1.80e-05	2	148	2	34506759
Pubmed	Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.	CREBBP EP300	1.80e-05	2	148	2	22177454
Pubmed	Attenuation of apoptosis by chromogranin A-induced Akt and survivin pathways in prostate cancer cells.	BIRC5 AKT1	1.80e-05	2	148	2	17584963
Pubmed	p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.	CREBBP EP300	1.80e-05	2	148	2	19729597
Pubmed	Normal endometrial stromal cells regulate survival and apoptosis signaling through PI3K/AKt/Survivin pathway in endometrial adenocarcinoma cells in vitro.	BIRC5 AKT1	1.80e-05	2	148	2	21794903
Pubmed	Interaction of human pregnancy-associated plasma protein-A with serine proteinases.	PAPPA PLG	1.80e-05	2	148	2	7586586
Pubmed	ON pathway mutations increase susceptibility to form-deprivation myopia.	GRM6 ITPR1	1.80e-05	2	148	2	26072023
Pubmed	Reciprocal regulation of Rag expression in thymocytes by the zinc-finger proteins, Zfp608 and Zfp609.	ZNF609 ZNF608	1.80e-05	2	148	2	23076336
Pubmed	CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.	CREBBP EP300	1.80e-05	2	148	2	39287984
Pubmed	A missense mutation in Grm6 reduces but does not eliminate mGluR6 expression or rod depolarizing bipolar cell function.	CACNA1F GRM6	1.80e-05	2	148	2	28490646
Pubmed	Pregnancy-associated plasma protein-A promotes TF procoagulant activity in human endothelial cells by Akt-NF-κB axis.	PAPPA AKT1	1.80e-05	2	148	2	27007282
Pubmed	CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.	CREBBP EP300	1.80e-05	2	148	2	32576962
Pubmed	A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.	CREBBP EP300	1.80e-05	2	148	2	24522976
Pubmed	CTGF/Hcs24, hypertrophic chondrocyte-specific gene product, interacts with perlecan in regulating the proliferation and differentiation of chondrocytes.	HSPG2 CCN2	1.80e-05	2	148	2	12811819
Pubmed	Potential biomarker of metformin action.	CREBBP EP300	1.80e-05	2	148	2	24639469
Pubmed	The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.	CREBBP EP300	1.80e-05	2	148	2	37816914
Pubmed	Binding of p300/CBP co-activators by polyoma large T antigen.	CREBBP EP300	1.80e-05	2	148	2	11438528
Pubmed	Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.	CREBBP EP300	1.80e-05	2	148	2	10918613
Pubmed	EGF prevents the neuroendocrine differentiation of LNCaP cells induced by serum deprivation: the modulator role of PI3K/Akt.	EGF AKT1	1.80e-05	2	148	2	17898861
Pubmed	Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.	CREBBP EP300	1.80e-05	2	148	2	19272189
Pubmed	Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.	CREBBP EP300	1.80e-05	2	148	2	32690000
Pubmed	Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel.	EGF SCN9A	1.80e-05	2	148	2	18036246
Pubmed	Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.	CREBBP EP300	1.80e-05	2	148	2	15860545
Pubmed	Dietary induction of colonic tumors in a mouse model of sporadic colon cancer.	APC MUC2	1.80e-05	2	148	2	18829535
Pubmed	Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.	CREBBP EP300	1.80e-05	2	148	2	29460469
Pubmed	Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.	CREBBP EP300	1.80e-05	2	148	2	24551300
Pubmed	Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.	CREBBP EP300	1.80e-05	2	148	2	33911074
Interaction	FOXQ1 interactions	ZNF609 TRPS1 CREBBP ZNF608 PELP1 POP1 KIF22 SYMPK	8.37e-06	141	145	8	int:FOXQ1
Interaction	TFF1 interactions	RAD51 APC CREBBP AKT1 EP300	1.09e-05	41	145	5	int:TFF1
Interaction	SOX7 interactions	ZNF609 TRPS1 CHD7 CREBBP ZNF608 EP300	2.79e-05	82	145	6	int:SOX7
Interaction	H2BC3 interactions	RAD51 PABPC4 NAP1L1 GON4L CHD7 NUDCD2 CREBBP PALB2 POP1 AKT1 EP300 KIF22	3.86e-05	406	145	12	int:H2BC3
Interaction	GSC interactions	ZNF609 TRPS1 CREBBP ZNF462 ZNF608 EP300	3.91e-05	87	145	6	int:GSC
Interaction	TEAD1 interactions	RAD51 ZNF609 TRPS1 CHD7 CREBBP ZNF462 ZNF608 EP300	4.16e-05	176	145	8	int:TEAD1
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	CREBBP HERC2 NBR1 EP300	3.33e-06	18	107	4	91
Coexpression	GSE24210_RESTING_TREG_VS_TCONV_UP	NUDT7 STIM2 EVI2B E2F8 ITPR1 ARRB1 CD22 HERC2 EP300	2.15e-06	200	148	9	M7839
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPS1 DNAH7 BICDL1 MAST4 SHANK2 EGF BICC1 EPB41L1 WDR72	2.04e-08	196	148	9	eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCell	COVID-19-kidney-TAL\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 SPTLC3 BICDL1 SHANK2 EGF BICC1 EPB41L1 WDR72	2.58e-07	191	148	8	fe55475ce0666ab5122447a813dc2369e24947b8
ToppCell	COVID-19-kidney-Mito-rich_Distal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 SPTLC3 BICDL1 SHANK2 EGF BICC1 EPB41L1 WDR72	2.58e-07	191	148	8	0965f621ebcd92ccdeb21cc27022180ce3cfe910
ToppCell	RV-02._Fibroblast_II\|RV / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PAPPA CCN2 BICC1	2.91e-07	194	148	8	11c79a8c56ece42713b04b321982e41e239f07a5
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PAPPA CCN2 BICC1	2.91e-07	194	148	8	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 BICDL1 SHANK2 EGF MAP3K21 BICC1 EPB41L1 WDR72	2.91e-07	194	148	8	93c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 BICDL1 MAST4 SHANK2 MAP3K21 BICC1 EPB41L1 WDR72	2.91e-07	194	148	8	5eaaa81f4b2535f983c424aaef00077089526a5c
ToppCell	COVID-19-Heart-Fib_2\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A4 TRPS1 SNED1 FBN1 PXDN PAPPA CCN2 BICC1	2.91e-07	194	148	8	d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCell	COVID-19-Heart-Fib_1\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PXDN CCN2 BICC1	3.02e-07	195	148	8	f423baa36ac7cdc383c033e35a7d17e6bf913323
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 BICDL1 MAST4 SHANK2 EGF BICC1 EPB41L1 WDR72	3.02e-07	195	148	8	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	HSPG2 FCN3 ZNF462 SNED1 MAST4 PXDN CCN2 SEC14L1	3.14e-07	196	148	8	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	Biopsy_IPF-Epithelial-KRT5-/KRT17+\|Biopsy_IPF / Sample group, Lineage and Cell type	COL4A4 SOX11 HSPG2 IL32 LRRN1 PXDN PAPPA NOTCH3	3.67e-07	200	148	8	2fc7a3b3aea711ad3d96fd9513f4b40533056d86
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	RAD51 MPO APBA1 BIRC5 E2F8 SKA1 FZD2	1.31e-06	164	148	7	ad508f53009efdd1dae7abcdb5431387f3f7e7b2
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DEF8 BIRC5 E2F8 ZNF462 SHANK2 WDR90 SKA1	1.53e-06	168	148	7	a7eb28e15b591997f1aee09501cb20ae18beca08
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DNAH7 SHANK2 MAP3K21 BICC1 ALPK2 EPB41L1 WDR72	1.53e-06	168	148	7	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SPTLC3 LRRN1 SNED1 MEGF6 PAPPA SCARA3 BICC1	2.71e-06	183	148	7	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 CACNA1F NCAM2 RYR3 KCNA4 SCN9A UNC80	2.81e-06	184	148	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 CACNA1F NCAM2 RYR3 KCNA4 SCN9A UNC80	2.81e-06	184	148	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 CACNA1F NCAM2 RYR3 KCNA4 SCN9A UNC80	2.81e-06	184	148	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 HSPG2 LRRN1 FBN1 C10orf105 CCN2 SCARA3	3.23e-06	188	148	7	6c6486cae9a8f2f8200598cb4bfd3fd513eb28a3
ToppCell	COVID-19-Heart-Fib_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PXDN BICC1	3.23e-06	188	148	7	fe361215f4ba841aa5e1e581fb56f2f4d3ccd201
ToppCell	RA-14._Fibroblast_III\|RA / Chamber and Cluster_Paper	COL4A4 SEPTIN9 TRPS1 APBA1 SNED1 FBN1 PAPPA	3.35e-06	189	148	7	46e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	COL4A4 SOX11 IL32 LRRN1 PXDN MICAL2 SPOCD1	3.35e-06	189	148	7	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	AFF2 BICDL1 MAST4 PAPPA BICC1 ALPK2 WDR72	3.35e-06	189	148	7	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 SNED1 MICAL2 CFAP74 CCN2 LTBP3 SCARA3	3.47e-06	190	148	7	3cf464664d6aa22b212e60b70885953887e92483
ToppCell	LV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 CCN2 BICC1	3.59e-06	191	148	7	d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCell	RV-01._Fibroblast_I\|RV / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PAPPA BICC1	3.72e-06	192	148	7	356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A4 TRPS1 ITPR1 SNED1 FBN1 PXDN BICC1	3.72e-06	192	148	7	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-AC-like-AC-like_Prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM120B CHD7 GRM6 E2F8 MAST4 CCN2 WDR90	3.72e-06	192	148	7	d6f656be2698bd215717d35f4e7ab727c08c61e0
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RAD51 MPO AFF2 BIRC5 E2F8 FBN1 SKA1	3.72e-06	192	148	7	0445fdc670fa7b847dcd0a061d7736ddcf3519ba
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 BICDL1 MAST4 SHANK2 BICC1 EPB41L1 WDR72	3.85e-06	193	148	7	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 BICDL1 MAST4 SHANK2 BICC1 EPB41L1 WDR72	3.85e-06	193	148	7	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PAPPA BICC1	3.85e-06	193	148	7	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	RV-02._Fibroblast_II\|World / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PAPPA BICC1	4.12e-06	195	148	7	ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 PAPPA BICC1	4.12e-06	195	148	7	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH7 BICDL1 SHANK2 MAP3K21 BICC1 EPB41L1 WDR72	4.26e-06	196	148	7	6ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MPP3 COL4A4 CACNA1F CHD7 SHANK2 LTBP3 MAP3K21	4.40e-06	197	148	7	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RAD51 MPO AFF2 BIRC5 E2F8 FBN1 SKA1	4.40e-06	197	148	7	bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCell	severe-Myeloid-Immature_Neutrophils_2\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	RAD51 MPO AFF2 BIRC5 E2F8 SKA1 KIF22	4.55e-06	198	148	7	844f534551483c89ef789d1cfeb4680e54f794b2
ToppCell	stromal_cell\|World / Lineage and Cell class	NCAM2 FBN1 PAPPA CCN2 SCARA3 BICC1 NOTCH3	4.70e-06	199	148	7	507a82d0529b5b1fa5aebcfe43db53f0b6e3f8f0
ToppCell	stromal_cell-stromal_cell\|World / Lineage and Cell class	NCAM2 FBN1 PAPPA CCN2 SCARA3 BICC1 NOTCH3	4.70e-06	199	148	7	74262363a34da3a1eb55ab375fd61ddd7bb39b23
ToppCell	Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	HSPG2 SNED1 FBN1 PXDN CCN2 LTBP3 SCARA3	4.70e-06	199	148	7	40de6d4a31cf22efa2864f79e4ec8e2b7bfc9d4a
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	MPP3 COL4A4 CACNA1F CHD7 SHANK2 CCN2 LTBP3	4.70e-06	199	148	7	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE-P1\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	EFCAB14 CPOX NUDCD2 ABHD17B SPOCD1 MAP4K4	6.60e-06	137	148	6	80f1a6cfb48ccfba1c3545fdcd5fcb3157272aca
ToppCell	facs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NCAM2 GRM6 AJM1 SCN9A PLG SKA1	8.78e-06	144	148	6	e9d62f202f0fa8747961036ef0eafed91fe8a42f
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAD51 BIRC5 RDM1 RYR3 CD22 SKA1	1.84e-05	164	148	6	4307b002fb41ddfc7ab8a6bca66a60942c250052
ToppCell	LPS-antiTNF-Epithelial_airway-Mes-Epi-like-Airway\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RAD51 BIRC5 RDM1 RYR3 CD22 SKA1	1.84e-05	164	148	6	1d84aa5b925f502ee9c5fa39714490f613a58028
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	MPO SPTLC3 FBN1 PXDN SCN9A BICC1	1.90e-05	165	148	6	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	RAD51 APBA1 BIRC5 E2F8 SKA1 FZD2	1.90e-05	165	148	6	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	facs-Liver-Hepatocytes-24m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1F BIRC5 SLC15A3 PALB2 AJM1 SKA1	1.97e-05	166	148	6	03a47b8687f54955e84df1edcb230db332c4ca8f
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	WNT10B APBA1 LMX1B NISCH SCN9A PAPPA	1.97e-05	166	148	6	6a6ed5c7a43fee9a8a9be42dfa99303815b8e8ef
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	RAD51 BIRC5 TEX14 SLC15A3 RSPH3 SKA1	2.04e-05	167	148	6	7efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 RNF31 SNED1 FBN1 MICAL2 CCN2	2.33e-05	171	148	6	972fab891135bd755d5526cbc5a963200067b0a6
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 MPO BIRC5 E2F8 SKA1 KIF22	2.33e-05	171	148	6	ff117bf1a0755aa7d7c3db29749a7b9b90cc0b2f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 RNF31 SNED1 FBN1 MICAL2 CCN2	2.33e-05	171	148	6	2a77ed79c6f2e700e789c80451a70ecb31639719
ToppCell	droplet-Spleen-SPLEEN-30m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPO BIRC5 CPOX E2F8 SKA1 KIF22	2.41e-05	172	148	6	02cc4a9fb7902c572cee37ba828749db4913ee87
ToppCell	367C-Myeloid-Dendritic-cDC_proliferating_1\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	LRRN1 WNT10B BIRC5 E2F8 FAM169A SKA1	2.65e-05	175	148	6	6b4e841bde6cfa4956e1a0231672cea20f11210c
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RAD51 SOX11 BIRC5 E2F8 SKA1 KIF22	2.74e-05	176	148	6	8813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-GC_B_(II)\|lymph-node_spleen / Manually curated celltypes from each tissue	AFF2 DEF8 SHANK2 ZNF608 CD22 SEC14L1	2.74e-05	176	148	6	5788dd5b23ebb52f19d3b5bdbcfe25dee349cf77
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC3 ITPK1 SNED1 CEP78 CD22 WDR72	2.92e-05	178	148	6	51d2188406f04329311b2efd1108fc36617a860e
ToppCell	390C-Lymphocytic-NK_cells-Proliferating_NK_cell\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RAD51 SOX11 BIRC5 E2F8 SKA1 KIF22	3.01e-05	179	148	6	e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BICDL1 SHANK2 PAPPA BICC1 ALPK2 WDR72	3.11e-05	180	148	6	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TEX14 CAPN13 MAST4 SHANK2 ZNF608 NOTCH3	3.11e-05	180	148	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	AT1-AT2_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	SOX11 IL32 PXDN PAPPA BICC1 NOTCH3	3.11e-05	180	148	6	3c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCell	RA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A4 AFF2 NCAM2 FBN1 PAPPA BICC1	3.20e-05	181	148	6	2b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell	10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1\|bone_marrow / Manually curated celltypes from each tissue	RAD51 MPO BIRC5 FZD2 SCARA3 BICC1	3.20e-05	181	148	6	ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 CD46 PSPH BICDL1 FBN1 NOTCH3	3.30e-05	182	148	6	be9c312a44868d4ee266a64d066feb8c5bce5687
ToppCell	facs-Lung-Endomucin-24m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AFF2 CD46 PSPH BICDL1 FBN1 NOTCH3	3.30e-05	182	148	6	74dbb706bcaa0f8c922bf3b0424bce5bb27167fa
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DNAH7 BICDL1 SHANK2 BICC1 ALPK2 WDR72	3.41e-05	183	148	6	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAD51 MPO BIRC5 E2F8 WDR90 SKA1	3.41e-05	183	148	6	6c1d7ce60e67bf1df364a4e177c351e7313eb41f
ToppCell	facs-Diaphragm-Limb_Muscle-18m-Lymphocytic-T_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RAD51 MPO BIRC5 ITPK1 SKA1 KIF22	3.51e-05	184	148	6	185b49630da61cbf45c0926d1b992943296d2a54
ToppCell	Bac-SEP-Lymphocyte-T_NK-T_NK_proliferative\|Bac-SEP / Disease, Lineage and Cell Type	RAD51 BIRC5 RDM1 E2F8 TNS4 SKA1	3.51e-05	184	148	6	848d05afd5a2ef61fb8a09c0f5fa2a56fd5c160b
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAD51 MPO BIRC5 E2F8 WDR90 SKA1	3.62e-05	185	148	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TRPS1 NCAM2 RYR3 FBN1 PAPPA UNC80	3.62e-05	185	148	6	7dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell	droplet-Spleen-nan-21m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SOX11 BIRC5 CPOX E2F8 RANGRF SKA1	3.62e-05	185	148	6	239cc5184825b3cc98638d4aec0a1de8e508d76c
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BICDL1 PAPPA PLG BICC1 ALPK2 WDR72	3.62e-05	185	148	6	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RAD51 BIRC5 RDM1 CHD7 FNDC10 KIF22	3.73e-05	186	148	6	4fe8e0bf74c7dbf73634cafdacad89020d2634d0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF462 MAST4 ZNF608 PAPPA BICC1 ALPK2	3.73e-05	186	148	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Control-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	PPFIBP2 LRRK1 SNED1 ZNF608 CD22 MAP4K4	3.84e-05	187	148	6	4e64be635f445276e71f2937f33f041c3a4204ab
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	AFF2 ZNF462 BICDL1 PAPPA BICC1 ALPK2	3.84e-05	187	148	6	9d77ca45f7563bd6f2a0c1be5d99d93ad30983f7
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 HSPG2 FBN1 FZD2 SCARA3 BICC1	3.84e-05	187	148	6	ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BICDL1 SHANK2 PAPPA BICC1 EPB41L1 WDR72	3.84e-05	187	148	6	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	IPF-Lymphoid-B\|Lymphoid / Disease state, Lineage and Cell class	PPFIBP2 LRRK1 ITPR1 SNED1 CD22 MAP4K4	3.84e-05	187	148	6	af1327559f7e01bec070881cae52834917c3da65
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPP3 APBA1 ZNF608 CCN2 BICC1 ALPK2	3.96e-05	188	148	6	b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCell	droplet-Lung-3m-Hematologic-Lymphocytic_NK_ILC-natural_killer_cell-proliferating_NK\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RAD51 BIRC5 E2F8 SKA1 ALPK2 KIF22	3.96e-05	188	148	6	0ec2a1b0505501ba18f10a5fce68c306a6292419
ToppCell	COVID-19-kidney-CD-PC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SHANK2 PAPPA MAP3K21 BICC1 EPB41L1 WDR72	3.96e-05	188	148	6	8f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MPP3 APBA1 ZNF608 CCN2 BICC1 ALPK2	3.96e-05	188	148	6	874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCell	facs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL4A4 HSPG2 FBN1 C10orf105 LTBP3 BICC1	3.96e-05	188	148	6	bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCell	Mesenchymal-myofibroblast_cell\|World / Lineage, Cell type, age group and donor	SOX11 SNED1 FBN1 PAPPA SCARA3 UNC80	4.08e-05	189	148	6	44e37f88137bb249933eb615235b2cf2ae7f3925
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PPFIBP2 SEPTIN9 ITPK1 PAPPA MAP3K21 WDR72	4.08e-05	189	148	6	532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRN1 PPFIBP2 PAPPA SCARA3 BICC1 NOTCH3	4.08e-05	189	148	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	LV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A4 TRPS1 NCAM2 SNED1 FBN1 BICC1	4.20e-05	190	148	6	12992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LRRK1 SNED1 FBN1 PXDN PAPPA BICC1	4.20e-05	190	148	6	0fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BICDL1 MAST4 PAPPA BICC1 ALPK2 WDR72	4.32e-05	191	148	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AFF2 FBN1 PAPPA FZD2 SCARA3 BICC1	4.32e-05	191	148	6	b51e0f5d1b93f526160c904e9091313a5364f3a7
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	BICDL1 MAST4 PAPPA BICC1 ALPK2 WDR72	4.32e-05	191	148	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T\|GI_small-bowel / Manually curated celltypes from each tissue	RAD51 MPO BIRC5 E2F8 SKA1 KIF22	4.32e-05	191	148	6	e642fa7395c05fb53324c9d46bbc52f89fc9673f
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	IL32 WHAMM BICDL1 TNRC6A CACNA1I NKTR	4.32e-05	191	148	6	d9a6f61fcda4f5352488f7f55cb9b57aeacc717f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITPR1 BICDL1 MAST4 SHANK2 EGF EPB41L1	4.32e-05	191	148	6	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	RSPO2 C10orf105 CCN2 LTBP3 SCARA3 EPB41L1	4.32e-05	191	148	6	5ee353c79055c08e8a3e2b43a0345bceb09f3890
Drug	stattic	MPO BIRC5 EGF AKT1 CCN2	1.45e-06	31	145	5	ctd:C517409
Drug	isotetrandrine	CACNA1F BIRC5 RYR3 ITPR1 AKT1 CACNA1I SCARA3	2.93e-06	97	145	7	CID000005422
Drug	Oxolinic acid [14698-29-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	MPP3 APC GON4L ITPR1 ABHD17B NKTR DCAF11 EPB41L1 NOTCH3	4.78e-06	196	145	9	2103_DN
Drug	Guanabenz acetate [23256-50-0]; Down 200; 13.8uM; PC3; HT_HG-U133A	AFF2 WNT10B APC LRRK1 SNED1 EGF CD22 CACNA1I NKTR	4.98e-06	197	145	9	4642_DN
Drug	tb-E	APBA1 BIRC5 CPOX EGF PCNT	1.21e-05	47	145	5	CID000006588
Disease	Prostatic Neoplasms	MPO RNF31 JADE2 PPFIBP2 WNT10B APC BIRC5 CHD7 CREBBP PALB2 ITPR1 EGF AKT1	9.39e-06	616	142	13	C0033578
Disease	Malignant neoplasm of prostate	MPO RNF31 JADE2 PPFIBP2 WNT10B APC BIRC5 CHD7 CREBBP PALB2 ITPR1 EGF AKT1	9.39e-06	616	142	13	C0376358
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.30e-05	2	142	2	180849
Disease	Rubinstein-Taybi syndrome due to CREBBP mutations	CREBBP EP300	2.30e-05	2	142	2	cv:C4551859
Disease	Menke-Hennekam syndrome	CREBBP EP300	2.30e-05	2	142	2	cv:C5681632
Disease	Rubinstein-Taybi syndrome (implicated_via_orthology)	CREBBP EP300	2.30e-05	2	142	2	DOID:1933 (implicated_via_orthology)
Disease	Rubinstein-Taybi syndrome	CREBBP EP300	2.30e-05	2	142	2	cv:C0035934
Disease	RUBINSTEIN-TAYBI SYNDROME 1	CREBBP EP300	2.30e-05	2	142	2	C4551859
Disease	Rubinstein-Taybi syndrome (is_implicated_in)	CREBBP EP300	2.30e-05	2	142	2	DOID:1933 (is_implicated_in)
Disease	Rubinstein-Taybi Syndrome	CREBBP EP300	2.30e-05	2	142	2	C0035934
Disease	Disproportionate short stature	HSPG2 TRPS1 FBN1 KIF22 PCNT	3.60e-05	77	142	5	C0878659
Disease	actinic keratosis	TRPS1 DEF8 HERC2	3.82e-05	14	142	3	EFO_0002496
Disease	hip circumference	SOX11 FOXO6 SEPTIN9 TRPS1 EVI2B SHANK2 FTO ALPK2 EPB41L1	4.01e-05	338	142	9	EFO_0005093
Disease	Neoplasm of uncertain or unknown behavior of breast	PALB2 AKT1 HERC2 EP300	4.53e-05	41	142	4	C0496956
Disease	Breast adenocarcinoma	PALB2 AKT1 HERC2 EP300	4.53e-05	41	142	4	C0858252
Disease	Breast Carcinoma	RAD51 WNT10B BIRC5 PALB2 EGF NISCH AKT1 HERC2 FTO EP300 NOTCH3	6.22e-05	538	142	11	C0678222
Disease	osteoarthritis, hip	LMX1B LTBP3 HERC2 FTO EP300	8.45e-05	92	142	5	EFO_1000786
Disease	Non-Small Cell Lung Carcinoma	APC BIRC5 E2F8 ZNF462 AKT1 NOTCH3	1.12e-04	156	142	6	C0007131
Disease	Congenital stationary night blindness	CACNA1F GRM6	1.37e-04	4	142	2	cv:C0339535
Disease	Renal glomerular disease	COL4A4 CREBBP LMX1B	1.80e-04	23	142	3	C0268731
Disease	Glomerulopathy Assessment	COL4A4 CREBBP LMX1B	1.80e-04	23	142	3	C4521256
Disease	refractive error	COL4A4 SEPTIN9 CHD7 ZNF462 FBN1 KCNA4 CACNA1I BICC1	1.90e-04	326	142	8	MONDO_0004892
Disease	Leukemia, Myelocytic, Acute	RAD51 SEPTIN9 CREBBP PALB2 PXDN EP300	1.97e-04	173	142	6	C0023467
Disease	hair colour measurement	FOXO6 PPFIBP2 TRPS1 DEF8 PXDN UBE2G2 KRT71 RSPO2 HERC2 FTO EPB41L1	2.00e-04	615	142	11	EFO_0007822
Disease	retinal vasculature measurement	HSPG2 SEPTIN9 ITPR1 KCNA4 PXDN RSPO2 LTBP3 HERC2 GTSCR1 WDR72	2.11e-04	517	142	10	EFO_0010554
Disease	pancreatic cancer (is_implicated_in)	MPO NAP1L1 APC PALB2 AKT1	2.13e-04	112	142	5	DOID:1793 (is_implicated_in)
Disease	Geleophysic dysplasia	FBN1 LTBP3	2.28e-04	5	142	2	C3489726
Disease	Acromicric Dysplasia	FBN1 LTBP3	2.28e-04	5	142	2	C0265287
Disease	Mammary Carcinoma, Human	RAD51 WNT10B BIRC5 PALB2 EGF NISCH AKT1 FTO EP300 NOTCH3	2.39e-04	525	142	10	C4704874
Disease	Mammary Neoplasms, Human	RAD51 WNT10B BIRC5 PALB2 EGF NISCH AKT1 FTO EP300 NOTCH3	2.39e-04	525	142	10	C1257931
Disease	Drugs used in diabetes use measurement	JADE2 PABPC4 EVI2B DNAH7 PPP4R3A LTBP3 FTO	2.45e-04	255	142	7	EFO_0009924
Disease	Mammary Neoplasms	RAD51 WNT10B BIRC5 PALB2 EGF NISCH AKT1 FTO EP300 NOTCH3	2.46e-04	527	142	10	C1458155
Disease	Carcinoma, Granular Cell	APC BIRC5 EGF CCN2 MUC2	2.51e-04	116	142	5	C0205644
Disease	Adenocarcinoma, Tubular	APC BIRC5 EGF CCN2 MUC2	2.51e-04	116	142	5	C0205645
Disease	Adenocarcinoma, Oxyphilic	APC BIRC5 EGF CCN2 MUC2	2.51e-04	116	142	5	C0205642
Disease	Carcinoma, Cribriform	APC BIRC5 EGF CCN2 MUC2	2.51e-04	116	142	5	C0205643
Disease	Adenocarcinoma, Basal Cell	APC BIRC5 EGF CCN2 MUC2	2.51e-04	116	142	5	C0205641
Disease	Adenocarcinoma	APC BIRC5 EGF CCN2 MUC2	2.51e-04	116	142	5	C0001418
Disease	Colorectal cancer	APC AKT1 EP300	2.93e-04	27	142	3	cv:C0346629
Disease	COLORECTAL CANCER	APC AKT1 EP300	2.93e-04	27	142	3	114500
Disease	Neoplasm of the large intestine	APC AKT1 EP300	2.93e-04	27	142	3	cv:C0009404
Disease	Malignant tumor of breast	RAD51 PALB2 AKT1	2.93e-04	27	142	3	cv:C0006142
Disease	Breast neoplasm	RAD51 PALB2 AKT1	2.93e-04	27	142	3	cv:C1458155
Disease	Familial cancer of breast	RAD51 PALB2 AKT1	2.93e-04	27	142	3	cv:C0346153
Disease	sexual dimorphism measurement	FOXO6 KCTD19 PABPC4 TRPS1 APC SNAP47 ZNF462 FBN1 ZNF608 TNRC6A PAPPA LTBP3 FTO SPOCD1 EPB41L1	2.97e-04	1106	142	15	EFO_0021796
Disease	Lung Neoplasms	MPO APC BIRC5 AKT1 CCN2 MAP4K4 NOTCH3	3.09e-04	265	142	7	C0024121
Disease	squamous cell carcinoma	TRPS1 DEF8 HERC2 EPB41L1	3.11e-04	67	142	4	EFO_0000707
Disease	Malignant neoplasm of lung	MPO APC BIRC5 AKT1 CCN2 MAP4K4 NOTCH3	3.16e-04	266	142	7	C0242379
Disease	primary ciliary dyskinesia (is_implicated_in)	DNAH7 CFAP74	3.41e-04	6	142	2	DOID:9562 (is_implicated_in)
Disease	Squamous cell carcinoma	BIRC5 CREBBP AKT1 EP300 NOTCH3	3.42e-04	124	142	5	C0007137
Disease	alcohol use disorder (implicated_via_orthology)	PSPH CREBBP RYR3 AKT1 EP300 NOTCH3	3.75e-04	195	142	6	DOID:1574 (implicated_via_orthology)
Disease	Rectal Neoplasms	APC MUC2	4.75e-04	7	142	2	C0034885
Disease	Rectal Carcinoma	APC MUC2	4.75e-04	7	142	2	C0007113
Disease	blood pressure, chronic obstructive pulmonary disease	ZDHHC18 PABPC4 TNRC6A	4.89e-04	32	142	3	EFO_0000341, EFO_0004325
Disease	Adenocarcinoma of lung (disorder)	PABPC4 APC CREBBP RANGRF AKT1 EP300	5.01e-04	206	142	6	C0152013
Disease	Early Childhood Epilepsy, Myoclonic	TNRC6A SCN9A	6.32e-04	8	142	2	C0393695
Disease	Idiopathic Myoclonic Epilepsy	TNRC6A SCN9A	6.32e-04	8	142	2	C0338478
Disease	Symptomatic Myoclonic Epilepsy	TNRC6A SCN9A	6.32e-04	8	142	2	C0338479
Disease	Benign Infantile Myoclonic Epilepsy	TNRC6A SCN9A	6.32e-04	8	142	2	C0751120
Disease	Myoclonic Encephalopathy	TNRC6A SCN9A	6.32e-04	8	142	2	C0438414
Disease	Myoclonic Absence Epilepsy	TNRC6A SCN9A	6.32e-04	8	142	2	C0393703
Disease	Malignant neoplasm of breast	RAD51 WNT10B BIRC5 GRM6 PALB2 EGF NISCH POP1 AKT1 HERC2 FTO SPOCD1 EP300 NOTCH3	7.01e-04	1074	142	14	C0006142
Disease	Myoclonic Epilepsy	TNRC6A SCN9A	8.10e-04	9	142	2	C0014550
Disease	Craniofacial Abnormalities	HSPG2 TRPS1 FGD1 LTBP3 EP300	9.70e-04	156	142	5	C0376634
Disease	Epilepsy, Myoclonic, Infantile	TNRC6A SCN9A	1.01e-03	10	142	2	C0917800
Disease	neutrophil count	MPO ZDHHC18 JADE2 SEPTIN9 PCDHA8 CD46 CHD7 TEX14 PSPH CREBBP MICAL2 TNRC6A AKT1 FTO MAP4K4 PCNT	1.03e-03	1382	142	16	EFO_0004833
Disease	body surface area	TRPS1 ITPK1 ZNF462 FBN1 ZNF608 TNRC6A PAPPA LTBP3 FTO SYMPK	1.14e-03	643	142	10	EFO_0022196
Disease	Myoclonic Astatic Epilepsy	TNRC6A SCN9A	1.23e-03	11	142	2	C0393702
Disease	high density lipoprotein particle size measurement	ZDHHC18 PABPC4 TRPS1 NISCH PLG	1.42e-03	170	142	5	EFO_0008592
Disease	Night blindness, congenital stationary, type 1	CACNA1F GRM6	1.47e-03	12	142	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	CACNA1F GRM6	1.47e-03	12	142	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	CACNA1F GRM6	1.47e-03	12	142	2	C1864877
Disease	stenosing tenosynovitis	LTBP3 FTO	1.47e-03	12	142	2	EFO_0010822
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	CACNA1F GRM6	1.47e-03	12	142	2	C1850362
Disease	X-Linked Csnb	CACNA1F GRM6	1.47e-03	12	142	2	C3711543
Disease	Intestinal Neoplasms	APC MUC2	1.47e-03	12	142	2	C0021841
Disease	Intestinal Cancer	APC MUC2	1.47e-03	12	142	2	C0346627
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	CACNA1F GRM6	1.47e-03	12	142	2	C1848172
Disease	amino acid measurement	SOX11 LRRN1 LRRK1 STK32C DNAH7 RYR3 PXDN PELP1 NISCH MUC2	1.69e-03	678	142	10	EFO_0005134
Disease	Benign tumor of pancreas	APC EP300	1.73e-03	13	142	2	C0347284
Disease	Infantile Severe Myoclonic Epilepsy	TNRC6A SCN9A	1.73e-03	13	142	2	C0751122
Disease	Cone-rod synaptic disorder, congenital nonprogressive	CACNA1F GRM6	1.73e-03	13	142	2	C4041558
Disease	gallbladder cancer (is_implicated_in)	APC EGF	1.73e-03	13	142	2	DOID:3121 (is_implicated_in)
Disease	eosinophil measurement	TRPS1 CHD7 PXDN PELP1	1.87e-03	108	142	4	EFO_0803540
Disease	hepatocellular carcinoma (is_implicated_in)	MPO APC RYR3 EGF MAP4K4	1.87e-03	181	142	5	DOID:684 (is_implicated_in)
Disease	Hypodontia	WNT10B LTBP3	2.01e-03	14	142	2	C0020608
Disease	Hereditary Breast and Ovarian Cancer Syndrome	RAD51 PALB2	2.01e-03	14	142	2	C0677776
Disease	basal cell carcinoma	FOXO6 TRPS1 DEF8 HERC2 EPB41L1	2.26e-03	189	142	5	EFO_0004193
Disease	macula measurement	COL4A4 FBN1 TNRC6A RSPO2 WDR72	2.26e-03	189	142	5	EFO_0008375
Disease	Small cell carcinoma of lung	CREBBP AKT1 EP300	2.26e-03	54	142	3	C0149925
Disease	N-acetylmethionine measurement	ITPR1 MICAL2	2.32e-03	15	142	2	EFO_0021427
Disease	clonal hematopoiesis mutation measurement	DEF8 ITPR1 HERC2	2.38e-03	55	142	3	EFO_0020949
Disease	keratinocyte carcinoma	TRPS1 DEF8 HERC2 EPB41L1	2.58e-03	118	142	4	EFO_0010176
Disease	T-Cell Lymphoma	AKT1 EP300	2.64e-03	16	142	2	C0079772
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	AKT1 BICC1	2.64e-03	16	142	2	DOID:0110861 (implicated_via_orthology)
Disease	Polyposis, Adenomatous Intestinal	APC AKT1	2.64e-03	16	142	2	C2713442
Disease	Familial Intestinal Polyposis	APC AKT1	2.64e-03	16	142	2	C2713443
Disease	pain	FOXO6 SEPTIN9 TERF1 ITPK1 CAPN13	2.64e-03	196	142	5	EFO_0003843
Disease	colorectal cancer (is_implicated_in)	SEPTIN9 APC AKT1 EP300	2.83e-03	121	142	4	DOID:9256 (is_implicated_in)
Disease	metabolic syndrome	PABPC4 TRPS1 TNRC6A PLG FTO	2.88e-03	200	142	5	EFO_0000195

Protein segments in the cluster

Peptide	Gene	Start	Entry
PFLEGCACTPERMAE	BIRC5	26	O15392
PPDQDDSMECVDSER	AKT1	451	P31749
DSMECVDSERRPHFP	AKT1	456	P31749
DPLIPCDLMDGRDAF	EP300	1616	Q09472
RDETFVQDGSMCGPD	ADAM5	321	Q6NVV9
EQFPGEMFPVACRET	CTCFL	626	Q8NI51
CMEGRGIPAPEEERT	AHSA1	301	O95433
SCSQMPAFSEPAGEE	ALPK2	666	Q86TB3
IDSDDTQFPPMRCGL	ADAM20	161	O43506
FTECGNAMERDPLEA	AFF2	1106	P51816
MLDQPGFPDCSIEAA	ACAD9	366	Q9H845
ASPEPSADEDDLMTC	AJM1	651	C9J069
DPDPLLSCDLMDGRD	CREBBP	1651	Q92793
LMSPGSCLEDFRAAP	COL4A4	1616	P53420
SVFEDPVDMPCGHDF	ANKIB1	341	Q9P2G1
TGPPGDMFSLDECRS	CAPN13	531	Q6MZZ7
EGFIARMCSPSPDAT	CEP78	646	Q5JTW2
CNDAFVEVGMPRSPS	BICC1	621	Q9H694
RASAPAEPDSACCME	BICDL1	11	Q6ZP65
ADPALCFLERVGMPD	CHD7	1811	Q9P2D1
AMPEPESLRAFDSDG	EFCAB14	466	O75071
CPVAMEEADDTVAPS	ARRB1	251	P49407
PCGDASIIPMLEFED	ADAT1	141	Q9BUB4
ESDCPDRSDEFGCMP	HSPG2	391	P98160
DRSDEFGCMPPQVVT	HSPG2	396	P98160
FEEPTCINPFEMDSD	RBSN	711	Q9H1K0
CINPFEMDSDSGPEA	RBSN	716	Q9H1K0
DSPCLPEAEAMFAIN	RAD51	316	Q06609
DSDPFSFDGPEIMGC	NAP1L1	241	P55209
RFDDMSSPGLELPSC	PPP4R3A	121	Q6IN85
PPVVGSDGFCMFFED	KCTD19	766	Q17RG1
MEPTRDCPLFGGAFS	RANGRF	1	Q9HD47
DCRSPGIGLVEEPMD	RDM1	171	Q8NG50
GSDMEAEEDPSPCAS	CACNA1F	271	O60840
LPEGRALPVFCDMDT	FCN3	111	O75636
EGFPSPPDFILMADC	VCPKMT	131	Q9H867
APTGSECPDRLAMDF	PABPC4	466	Q13310
EDSPDRGACSTPDMP	EPB41L1	676	Q9H4G0
FSCDGMRPEAIRQDP	MAP4K4	881	O95819
RMPDSRFPLEGASDA	PCDHA8	146	Q9Y5H6
EDDRICSPPFMELTS	ITPK1	121	Q13572
CSPPFMELTSLCGDD	ITPK1	126	Q13572
FSDACEEPPTFEAME	CD46	31	P15529
MSAPFEERSGVVPCG	NUDCD2	1	Q8WVJ2
PFTDCGDGPMLRLEE	ITPR1	526	Q14643
GPEESAVCPERAMET	LRRK1	16	Q38SD2
CPCIPMFDLEGSLDE	HERC2	4361	O95714
DAVPLCMSADFPRVG	FTO	166	Q9C0B1
RSPEGEDGNEMVFCD	JADE2	206	Q9NQC1
TSCSPGFELMEAPGE	MUC2	4971	Q02817
SDPPCVRGMDSCSLE	KIF22	61	Q14807
IPCFLAGDTRSSEMP	MPO	396	P05164
RSPFADGETPDICMD	EVI2B	241	P34910
DMPESEECASAPAPV	DCAF11	521	Q8TEB1
EPARPDGSMFFSQEE	FZD2	226	Q14332
EDCGPERRATAPAMA	FOXO6	51	A8MYZ6
ASFCGGALEPMPTEE	NOTCH3	1796	Q9UM47
VCFPGGKRDPTDMDD	NUDT7	71	P0C024
PCMETEPSFETGDLC	PAPPA	586	Q13219
CRFEMEGLPVDESDS	OC90	101	Q02509
AAMLADFIDCPPDDE	PELP1	1106	Q8IZL8
SFLMSPESVRECEQP	PCNT	1241	O95613
ESTDYICPMEPSDGV	PPFIBP2	831	Q8ND30
EGEESPPAICMEVFL	GTSCR1	66	Q86UQ5
VAPDDNDRPTTDMCS	PALB2	711	Q86YC2
GDFPDCPAGMLFAEE	POP1	661	Q99575
PATEEPGESFCDKVM	IL32	141	P24001
DEFTCEACPGDMRPT	GRM6	551	O15303
PDMCFVELPGVEFRA	E2F8	241	A0AVK6
RRPADTEDGMSSCPQ	EGF	1081	P01133
TVAPEMCPIRATEDF	FBN1	371	P35555
DTFGPDPTMIRANCL	CCN2	186	P29279
EPAECVEFTAEPAGM	FNDC10	166	F2Z333
DEESRRPCAMVTPGA	BFSP1	566	Q12934
STAVSPDPENFLCEM	CACNA1I	1911	Q9P0X4
LMDPISDPEFFGSCK	DNAH7	3556	Q8WXX0
EELASSPVCMDSFQP	GON4L	471	Q3T8J9
SPTRDCDDQRPMDGD	APBA1	386	Q02410
EDYMSDLRCGDPENP	FAM169A	21	Q9Y6X4
MDVDECQDPAACRPG	LTBP3	1081	Q9NS15
FGNFPEPDMCVGESV	HEPHL1	276	Q6MZM0
DTCREPSMELCFPET	MAST4	1991	O15021
GEPEFRCPERVMDLG	DEF8	111	Q6ZN54
MPACAASSLPRVDDV	SEC14L1	641	Q92503
TAFPDGRSSFCGEMP	SLC15A3	121	Q8IY34
AGDDEDMPTFPCTQK	SCARA3	21	Q6AZY7
RCSSFMAPPVTDLGE	CPOX	126	P36551
TFKFLPASEPCEMDD	CFAP74	651	Q9C0B2
PASEPCEMDDSQSAL	CFAP74	656	Q9C0B2
GDAESSEMQRPPPDC	CD22	776	P20273
DAESRQEVPMCTGPE	FAM120B	346	Q96EK7
TTVFLDCRAMAEPEP	LRRN1	441	Q6UXK5
SDPAEMTSDECQPAE	MICAL2	1366	O94851
MSPACEDTAAPFDEQ	MPP3	516	Q13368
EDRRGCSPLEEPMVD	MEGF6	446	O75095
FLEGFPCSPRLDEMS	SND1-IT1	66	Q9HBX3
FMACSPVALDESDPD	SOX11	26	P35716
DAPCPAPFMAEEASS	TEX14	601	Q8IWB6
ARMCISGFDEPVPDL	TSEN54	471	Q7Z6J9
EMPFITCDEFNGVPS	SKA1	136	Q96BD8
KPREDVSMTSCEPFG	SNAP47	236	Q5SQN1
GREPALMPRLDTDCS	MAP3K21	846	Q5TCX8
DDNMEICTPDRSSPA	NKTR	1126	P30414
LPECFDTSRPLGDSM	NBR1	736	Q14596
CPGPTLSEDREMEEA	FGD1	926	P98174
SEEPSGRKESQEMCP	HOATZ	6	Q6PI97
MEEPQAGDAARFSCP	POLR1G	1	O15446
AEAEPMNSDEPEACF	SCN9A	1141	Q15858
PSCVGDMADTPRDAG	SEPTIN9	246	Q9UHD8
RPRDSLESFSCPGSM	WHAMM	696	Q8TF30
CSAPGPLFDLMERVS	SPTLC3	131	Q9NUV7
PDVETPSEEDCMFGN	PLG	471	P00747
SAMPACLSDVESDPR	POU4F3	171	Q15319
DECPDGFAPLEETME	RSPO2	126	Q6UXX9
PEGFMGLDCRERVPD	SNED1	456	Q8TER0
TRPSMFPEEGDFADE	SHANK2	1121	Q9UPX8
DEAERSALPMCGPIC	STK32C	466	Q86UX6
PDPTYTLMCDESGSR	ABHD17B	31	Q5VST6
SFTPGDDMPRVYCVE	APC	1631	P25054
DTDADSCPLMAEENP	CNGB1	471	Q14028
PGPEDNRSHCDYMES	C10orf105	116	Q8TEF2
DMVCPACGRPDLTDD	RNF31	741	Q96EP0
MDPGRQPESADDFDR	PDCD11	1596	Q14690
AEADDPQDMACTPSG	TRPS1	131	Q9UHF7
VDMECQTDAFLDRPP	RSPH3	271	Q86UC2
ARDGCPEPSAAMLFV	WDR90	561	Q96KV7
MASAGGEDCESPAPE	UCK1	1	Q9HA47
KAGRRMFSCPEESDP	ZSCAN5DP	41	P0CG00
MFSCPEESDPIQALR	ZSCAN5DP	46	P0CG00
APEECRSFMSGRPSQ	UNC80	996	Q8N2C7
EEMTFSCRASGSPEP	NCAM2	226	O15394
ATDMEACPPADAFIG	PSPH	181	P78330
DPCMSLSPPCFTEED	STIM2	51	Q9P246
DAPFTTCPEGPARDM	TNS4	421	Q8IZW8
GSVSEPDMAANFCPD	RYR3	2346	Q15413
LDTEASRACSGPFME	SPOCD1	401	Q6ZMY3
DPACSQSGPMEAEED	SPOCD1	571	Q6ZMY3
ESFLGPRMCTEDLPF	PISD	216	Q9UG56
MATARTFGPEREAEP	NISCH	1	Q9Y2I1
FATGPPTECMRDENE	PXDN	951	Q92626
APPRFCDSPTSDLEM	ZNF609	351	O15014
DMPDRCALEESESPG	WDR72	1071	Q3MJ13
MAEDVSSAAPSPRGC	TERF1	1	P54274
PECETPGIFISMDDD	SYMPK	1196	Q92797
PRFCESPTSDLEMRG	ZNF608	416	Q9ULD9
SERDGPPVENEMFFC	ZNF462	1181	Q96JM2
TFMDPGVFPRADEDE	ZDHHC8	66	Q9ULC8
FEKSPDFCERDPTMG	WNT10B	311	O00744
DFCERDPTMGSPGTR	WNT10B	316	O00744
PETCPFFEEMDALVS	ZSCAN29	481	Q8IWY8
SAPGSDPELASECMD	TNRC6A	241	Q8NDV7
DEPACRAKPDASMVG	ZDHHC18	371	Q9NUE0
IMGPEDTCFEFGVFP	UBE2G2	41	P60604
SFPHCSDLMPSGSEE	KCNA4	101	P22459
LESEECRMSGEFPSP	KRT71	436	Q3SY84
MDIATGPESLERCFP	LMX1B	1	O60663