Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	HULC complex	RNF20 RNF40	1.02e-04	4	87	2	GO:0033503
Domain	BAF250_C	ARID1B ARID1A	2.05e-05	2	85	2	IPR033388
Domain	BAF250_C	ARID1B ARID1A	2.05e-05	2	85	2	PF12031
Domain	BAF250/Osa	ARID1B ARID1A	2.05e-05	2	85	2	IPR021906
Domain	Cadherin_CS	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.40e-04	109	85	5	IPR020894
Domain	CADHERIN_1	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.66e-04	113	85	5	PS00232
Domain	Cadherin	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.66e-04	113	85	5	PF00028
Domain	CADHERIN_2	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.72e-04	114	85	5	PS50268
Domain	-	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.72e-04	114	85	5	2.60.40.60
Domain	CA	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.80e-04	115	85	5	SM00112
Domain	Cadherin-like	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.87e-04	116	85	5	IPR015919
Domain	Cadherin	DSG2 PCDHA7 PCDHA4 PCDHA1 PCDHB16	2.03e-04	118	85	5	IPR002126
Domain	Cadherin_2	PCDHA7 PCDHA4 PCDHA1 PCDHB16	2.19e-04	65	85	4	PF08266
Domain	Cadherin_N	PCDHA7 PCDHA4 PCDHA1 PCDHB16	2.19e-04	65	85	4	IPR013164
Domain	Cadherin_tail	PCDHA7 PCDHA4 PCDHA1	6.32e-04	37	85	3	PF15974
Domain	Cadherin_CBD	PCDHA7 PCDHA4 PCDHA1	6.32e-04	37	85	3	IPR031904
Domain	SAM/pointed	SAMD11 PPFIBP1 L3MBTL3 MAP3K5	2.00e-03	117	85	4	IPR013761
Domain	-	ARID1B ARID1A	2.07e-03	15	85	2	1.10.150.60
Domain	BRIGHT	ARID1B ARID1A	2.07e-03	15	85	2	SM00501
Domain	ARID_dom	ARID1B ARID1A	2.07e-03	15	85	2	IPR001606
Domain	ARID	ARID1B ARID1A	2.07e-03	15	85	2	PS51011
Domain	ARID	ARID1B ARID1A	2.07e-03	15	85	2	PF01388
Domain	Znf_ZZ	ZZZ3 TADA2A	3.33e-03	19	85	2	IPR000433
Domain	ZnF_ZZ	ZZZ3 TADA2A	3.33e-03	19	85	2	SM00291
Domain	Znf_C2H2_jaz	HIVEP2 GPATCH8	4.46e-03	22	85	2	IPR022755
Domain	zf-C2H2_jaz	HIVEP2 GPATCH8	4.46e-03	22	85	2	PF12171
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CEP350 KIAA1671 MAGI1 HIVEP2 NF1 DSG2 MYCBP2 SAMD11 PLEKHG3 PATZ1 PPFIBP1 MAP4K1 COBLL1 MCCC1 KIAA1191 NCKAP5L PABIR2 CEP170B ITPKB	3.57e-13	861	87	19	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TBC1D16 HIVEP3 HIVEP2 SETD1B RARG WIZ MYCBP2 CTC1 KIF26A ZNF398 RNF40 ARID1A LARS2 MED13 CEP170B PRRC2B MAP3K5	1.85e-09	1105	87	17	35748872
Pubmed	Interaction network of human early embryonic transcription factors.	KIAA1671 BPTF ARID1B HIVEP2 ZZZ3 WIZ TADA2A ARID1A MGA PRRC2B	1.94e-08	351	87	10	38297188
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	KIAA1671 ZZZ3 WIZ KIF15 MYCBP2 RNF40 TADA2A MCCC1 MGA L3MBTL3	9.92e-08	418	87	10	34709266
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	KIAA1671 BPTF ZNF469 ARID1B ZZZ3 ATXN7L2 WIZ DSG2 PATZ1 TADA2A ARID1A NCKAP5L MGA CEP170B PRRC2B	1.09e-07	1116	87	15	31753913
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	KIAA1671 BPTF ARID1B ZZZ3 WIZ DSG2 MYCBP2 ARID1A GPRIN1 MGA PRRC2B	1.30e-07	549	87	11	38280479
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	KIAA1671 ZZZ3 SETD1B KIF15 RNF40 MCCC1 BSN ARID1A NCKAP5L CEP170B PRRC2B	2.58e-07	588	87	11	38580884
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PLEKHG3 GPATCH8 MGA MED13 ECE2 PRRC2B	2.71e-07	105	87	6	9628581
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CEP350 KIAA1671 ARID1B WIZ KIF15 MYCBP2 KCNMA1 ARID1A GPRIN1 NCKAP5L L3MBTL3 PABIR2 PRRC2B EHD4	3.30e-07	1049	87	14	27880917
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	ARID1B WIZ RNF20 RNF40 ARID1A MGA MED13 PRRC2B	3.87e-07	268	87	8	33640491
Pubmed	RNF20/40-mediated eEF1BδL monoubiquitylation stimulates transcription of heat shock-responsive genes.	RNF20 RNF40 HSF1	5.25e-07	7	87	3	30649429
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MAGI1 NF1 WIZ KIF15 DSCAM MYCBP2 PATZ1 KCNMA1 BSN MGA CEP170B PRRC2B MAP3K5	8.00e-07	963	87	13	28671696
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ARID1B NF1 SETD1B MYCBP2 RNF20 ABT1 RNF40 GPATCH8 ARID1A	1.64e-06	440	87	9	34244565
Pubmed	Identification and Functional Characterization of a Novel Androgen Receptor Coregulator, EAP1.	ARID1B RNF20 RNF40 ARID1A	3.12e-06	40	87	4	34585037
Pubmed	A human MAP kinase interactome.	CEP350 MAGI1 HIVEP2 KIF26A COBLL1 NCKAP5L MGA CCDC88B MAP3K5	3.69e-06	486	87	9	20936779
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	CEP350 KIAA1671 NEO1 WIZ DSCAM DSG2 PPFIBP1 MCCC1 GPRIN1 MGA PRRC2B	3.86e-06	777	87	11	35844135
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	BPTF ZZZ3 SRSF2 ATXN7L2 WIZ PATZ1 RNF20 RNF40 TADA2A MCCC1 GPATCH8 ARID1A MGA L3MBTL3	3.89e-06	1294	87	14	30804502
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	BPTF ZZZ3 WIZ ARID1A MGA MED13	4.10e-06	167	87	6	20362541
Pubmed	A High-Density Map for Navigating the Human Polycomb Complexome.	BPTF HIVEP2 ZZZ3 SETD1B WIZ MYCBP2 TADA2A MGA L3MBTL3	4.28e-06	495	87	9	27705803
Pubmed	Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.	ARID1B ARID1A	6.19e-06	2	87	2	34386776
Pubmed	Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.	ARID1B ARID1A	6.19e-06	2	87	2	23202128
Pubmed	Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.	RNF20 RNF40	6.19e-06	2	87	2	22354749
Pubmed	Elucidating the impact of neurofibromatosis-1 germline mutations on neurofibromin function and dopamine-based learning.	TH NF1	6.19e-06	2	87	2	25788518
Pubmed	ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.	ARID1B ARID1A	6.19e-06	2	87	2	33890484
Pubmed	ARID1B is a specific vulnerability in ARID1A-mutant cancers.	ARID1B ARID1A	6.19e-06	2	87	2	24562383
Pubmed	Tight coordination of protein translation and HSF1 activation supports the anabolic malignant state.	NF1 HSF1	6.19e-06	2	87	2	23869022
Pubmed	RNF20/RNF40 ameliorates streptozotocin-induced type 1 diabetes by activating vitamin D receptors in vivo.	RNF20 RNF40	6.19e-06	2	87	2	37422774
Pubmed	Uncoupling of growth plate maturation and bone formation in mice lacking both Schnurri-2 and Schnurri-3.	HIVEP3 HIVEP2	6.19e-06	2	87	2	20404140
Pubmed	MAGI-1 interacts with Slo1 channel proteins and suppresses Slo1 expression on the cell surface.	MAGI1 KCNMA1	6.19e-06	2	87	2	19403801
Pubmed	Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.	ARID1B ARID1A	6.19e-06	2	87	2	37611161
Pubmed	Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.	ARID1B ARID1A	6.19e-06	2	87	2	32791957
Pubmed	ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.	ARID1B ARID1A	6.19e-06	2	87	2	29890703
Pubmed	E3 Ubiquitin Ligases RNF20 and RNF40 Are Required for Double-Stranded Break (DSB) Repair: Evidence for Monoubiquitination of Histone H2B Lysine 120 as a Novel Axis of DSB Signaling and Repair.	RNF20 RNF40	6.19e-06	2	87	2	30692271
Pubmed	RNF20 and RNF40 regulate vitamin D receptor-dependent signaling in inflammatory bowel disease.	RNF20 RNF40	6.19e-06	2	87	2	34088983
Pubmed	SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.	ARID1B ARID1A	6.19e-06	2	87	2	24788099
Pubmed	Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.	ARID1B ARID1A	6.19e-06	2	87	2	28967863
Pubmed	Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.	ARID1B ARID1A	6.19e-06	2	87	2	33052929
Pubmed	Mint3-depletion-induced energy stress sensitizes triple-negative breast cancer to chemotherapy via HSF1 inactivation.	APBA3 HSF1	6.19e-06	2	87	2	38081808
Pubmed	Two genes encode factors with NF-kappa B- and H2TF1-like DNA-binding properties.	HIVEP3 HIVEP2	6.19e-06	2	87	2	2247438
Pubmed	Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells.	RNF20 RNF40	6.19e-06	2	87	2	20738173
Pubmed	Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.	ARID1B ARID1A	6.19e-06	2	87	2	27562491
Pubmed	Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation.	RNF20 RNF40	6.19e-06	2	87	2	34290256
Pubmed	Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.	PCDHA7 PCDHA4 PCDHA1	6.73e-06	15	87	3	15640798
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	CEP350 KIAA1671 BPTF NF1 SRSF2 DSG2 MYCBP2 PLEKHG3 APMAP EMG1 MGA EHD4	9.28e-06	1024	87	12	24711643
Pubmed	Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.	PCDHA7 PCDHA4 PCDHA1	1.00e-05	17	87	3	29911975
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	TBC1D16 NF1 DSG2 MYCBP2 SAMD11 PLEKHG3 GPATCH8 KIAA1191 NCKAP5L PABIR2 MED13 CEP170B PRRC2B	1.01e-05	1215	87	13	15146197
Pubmed	Human transcription factor protein interaction networks.	KIAA1671 BPTF ARID1B ZZZ3 ATXN7L2 WIZ SAMD11 TADA2A MCCC1 GPATCH8 ARID1A MGA L3MBTL3 PRRC2B	1.20e-05	1429	87	14	35140242
Pubmed	CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.	PCDHA7 PCDHA4 PCDHA1	1.20e-05	18	87	3	15570159
Pubmed	Genomic organization of the family of CNR cadherin genes in mice and humans.	PCDHA7 PCDHA4 PCDHA1	1.20e-05	18	87	3	10662547
Pubmed	Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.30e-05	57	87	4	32633719
Pubmed	CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	1.40e-05	58	87	4	30377227
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KIAA1671 MAGI1 ARID1B NF1 PPFIBP1 ARID1A NCKAP5L CEP170B	1.66e-05	446	87	8	24255178
Pubmed	Loss of ARID1B and SMARCB1 expression are specific for the diagnosis of dedifferentiated/undifferentiated carcinoma in tumours of the upper gynaecological tract and cervix.	ARID1B ARID1A	1.85e-05	3	87	2	33432679
Pubmed	Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.	ARID1B ARID1A	1.85e-05	3	87	2	21647563
Pubmed	The tumor suppressor CDC73 interacts with the ring finger proteins RNF20 and RNF40 and is required for the maintenance of histone 2B monoubiquitination.	RNF20 RNF40	1.85e-05	3	87	2	22021426
Pubmed	RNF20-RNF40: A ubiquitin-driven link between gene expression and the DNA damage response.	RNF20 RNF40	1.85e-05	3	87	2	21827756
Pubmed	TNPO1-mediated nuclear import of ARID1B promotes tumor growth in ARID1A-deficient gynecologic cancer.	ARID1B ARID1A	1.85e-05	3	87	2	34044070
Pubmed	Genome-Wide Transcriptional Regulation Mediated by Biochemically Distinct SWI/SNF Complexes.	ARID1B ARID1A	1.85e-05	3	87	2	26716708
Pubmed	The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and primary high-grade serous ovarian cancer.	RNF20 RNF40	1.85e-05	3	87	2	27798111
Pubmed	Histone H2B ubiquitin ligases RNF20 and RNF40 in androgen signaling and prostate cancer cell growth.	RNF20 RNF40	1.85e-05	3	87	2	22155569
Pubmed	Motor and learning dysfunction during postnatal development in mice defective in dopamine neuronal transmission.	TH POMC	1.85e-05	3	87	2	9822156
Pubmed	Mouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcription.	SRSF2 ABT1	1.85e-05	3	87	2	20356838
Pubmed	Dampening of death pathways by schnurri-2 is essential for T-cell development.	HIVEP3 HIVEP2	1.85e-05	3	87	2	21475200
Pubmed	Mutations affecting components of the SWI/SNF complex cause Coffin-Siris syndrome.	ARID1B ARID1A	1.85e-05	3	87	2	22426308
Pubmed	Loss of tumor suppressor NF1 activates HSF1 to promote carcinogenesis.	NF1 HSF1	1.85e-05	3	87	2	22945628
Pubmed	Exome sequencing reveals frequent inactivating mutations in ARID1A, ARID1B, ARID2 and ARID4A in microsatellite unstable colorectal cancer.	ARID1B ARID1A	1.85e-05	3	87	2	24382590
Pubmed	ARID1A, ARID1B, and ARID2 Mutations Serve as Potential Biomarkers for Immune Checkpoint Blockade in Patients With Non-Small Cell Lung Cancer.	ARID1B ARID1A	1.85e-05	3	87	2	34512623
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	ARID1B ATXN7L2 WIZ ARID1A MGA	2.26e-05	134	87	5	25452129
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BPTF NF1 SRSF2 MYCBP2 MAP4K1 RNF20 GPATCH8 HSF1 GPRIN1 MED13	2.40e-05	774	87	10	15302935
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	2.63e-05	68	87	4	11230163
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	UBQLN2 NF1 MYCBP2 KCNMA1 BSN GPRIN1 CEP170B	2.73e-05	347	87	7	17114649
Pubmed	Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.	PCDHA7 PCDHA4 PCDHA1	2.95e-05	24	87	3	24698270
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	3.30e-05	72	87	4	10380929
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	CEP350 UBQLN2 DSG2 MYCBP2 MCCC1 PRRC2B	3.36e-05	242	87	6	34011540
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CEP350 HIVEP3 PLEKHG3 PPFIBP1 COBLL1 FAM169A KIAA1191 MGA	3.38e-05	493	87	8	15368895
Pubmed	A direct physical interaction between Nanog and Sox2 regulates embryonic stem cell self-renewal.	BPTF WIZ PATZ1 ARID1A MGA	3.41e-05	146	87	5	23892456
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	3.68e-05	74	87	4	10817752
Pubmed	Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination.	RNF20 RNF40	3.70e-05	4	87	2	28453857
Pubmed	TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.	RNF20 RNF40	3.70e-05	4	87	2	26781088
Pubmed	Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.	RNF20 RNF40	3.70e-05	4	87	2	21362549
Pubmed	Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes.	RNF20 RNF40	3.70e-05	4	87	2	38517892
Pubmed	Egr2-guided histone H2B monoubiquitination is required for peripheral nervous system myelination.	RNF20 RNF40	3.70e-05	4	87	2	32672815
Pubmed	SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms.	RNF20 RNF40	3.70e-05	4	87	2	24441044
Pubmed	Ring finger 20/ring finger 40/WW domain-containing adaptor with coiled-coil complex interacts with p53 to regulate gene transcription in DNA damage response.	RNF20 RNF40	3.70e-05	4	87	2	33868474
Pubmed	Undifferentiated Endometrial Carcinomas Show Frequent Loss of Core Switch/Sucrose Nonfermentable Complex Proteins.	ARID1B ARID1A	3.70e-05	4	87	2	28863077
Pubmed	Two related ARID family proteins are alternative subunits of human SWI/SNF complexes.	ARID1B ARID1A	3.70e-05	4	87	2	15170388
Pubmed	Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein.	ARID1B ARID1A	3.70e-05	4	87	2	11988099
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	4.30e-05	77	87	4	10835267
Pubmed	Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.	PCDHA7 PCDHA4 PCDHA1	4.73e-05	28	87	3	15347688
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHA7 PCDHA4 PCDHA1 PCDHB16	5.00e-05	80	87	4	10716726
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	CEP350 KIAA1671 DSG2 PPFIBP1 MCCC1 KIAA1191 NCKAP5L MGA CEP170B PRRC2B	5.44e-05	853	87	10	28718761
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	BPTF ARID1B WIZ ARID1A	5.77e-05	83	87	4	28794006
Pubmed	Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development.	TH NEO1 DSCAM	5.85e-05	30	87	3	32562661
Pubmed	Recent advances in understanding chromatin remodeling by Swi/Snf complexes.	ARID1B ARID1A	6.16e-05	5	87	2	12672490
Pubmed	Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.	ARID1B ARID1A	6.16e-05	5	87	2	12200431
Pubmed	Mediation of TNF receptor-associated factor effector functions by apoptosis signal-regulating kinase-1 (ASK1).	TRAF5 MAP3K5	6.16e-05	5	87	2	10523862
Pubmed	WAC, a functional partner of RNF20/40, regulates histone H2B ubiquitination and gene transcription.	RNF20 RNF40	6.16e-05	5	87	2	21329877
Pubmed	Increased genomic instability and reshaping of tissue microenvironment underlie oncogenic properties of Arid1a mutations.	ARID1B ARID1A	6.16e-05	5	87	2	38489371
Pubmed	Genome-Wide Meta-Analysis Identifies Multiple Novel Rare Variants to Predict Common Human Infectious Diseases Risk.	MACROD2 ITPKB	6.16e-05	5	87	2	37108169
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KIAA1671 HIVEP3 MAGI1 BPTF HIVEP2 MYCBP2 PLEKHG3 APMAP KCNMA1 ARID1A CEP170B PCDHB16 ITPKB	8.25e-05	1489	87	13	28611215
Interaction	YWHAQ interactions	CEP350 KIAA1671 TH HIVEP2 NF1 DSG2 MYCBP2 SAMD11 PLEKHG3 PPFIBP1 COBLL1 RNF20 KCNMA1 MCCC1 HSF1 LARS2 NCKAP5L PABIR2 CEP170B MAP3K5	2.87e-08	1118	85	20	int:YWHAQ
Interaction	EGR2 interactions	ARID1B HIVEP2 WIZ RNF20 RNF40 ARID1A MGA PRRC2B	6.30e-07	171	85	8	int:EGR2
Interaction	SFN interactions	CEP350 KIAA1671 MAGI1 SRSF2 DSG2 MYCBP2 PLEKHG3 PPFIBP1 APMAP COBLL1 NCKAP5L PABIR2 CEP170B MAP3K5	1.11e-06	692	85	14	int:SFN
Interaction	WWTR1 interactions	KIAA1671 BPTF ARID1B ZZZ3 WIZ DSG2 MYCBP2 ABT1 ARID1A GPRIN1 PRRC2B	1.58e-06	422	85	11	int:WWTR1
Interaction	KDM1A interactions	CEP350 KIAA1671 C4orf17 ZZZ3 WIZ KIF15 MYCBP2 PLEKHG3 GSTCD RNF40 TADA2A MCCC1 HSF1 MGA L3MBTL3 ECE2	1.71e-06	941	85	16	int:KDM1A
Interaction	PHF21A interactions	KIAA1671 ZZZ3 KIF15 MYCBP2 RNF40 TADA2A MCCC1 NCKAP5L MGA L3MBTL3	1.81e-06	343	85	10	int:PHF21A
Interaction	YWHAH interactions	CEP350 KIAA1671 MAGI1 HIVEP2 NF1 DSG2 MYCBP2 SAMD11 PLEKHG3 PPFIBP1 COBLL1 KCNMA1 KIAA1191 NCKAP5L PABIR2 CEP170B MAP3K5	2.89e-06	1102	85	17	int:YWHAH
Interaction	YWHAG interactions	CEP350 KIAA1671 MAGI1 HIVEP2 NF1 KIF15 DSG2 MYCBP2 SAMD11 PLEKHG3 PPFIBP1 COBLL1 KCNMA1 NCKAP5L PABIR2 CEP170B MAP3K5 ITPKB	3.62e-06	1248	85	18	int:YWHAG
Interaction	YWHAB interactions	CEP350 KIAA1671 MAGI1 TH NF1 DSG2 MYCBP2 PLEKHG3 PPFIBP1 COBLL1 KCNMA1 NCKAP5L PABIR2 CEP170B MAP3K5 ITPKB	4.46e-06	1014	85	16	int:YWHAB
Interaction	CDH19 interactions	ZZZ3 MYCBP2 TADA2A MGA	7.43e-06	30	85	4	int:CDH19
Interaction	SIRT6 interactions	ARID1B NF1 SETD1B WIZ MYCBP2 SAMD11 PATZ1 RNF20 ABT1 RNF40 GPATCH8 ARID1A	1.24e-05	628	85	12	int:SIRT6
Interaction	HNF4A interactions	BPTF ARID1B ZZZ3 WIZ TADA2A ARID1A MGA L3MBTL3	2.11e-05	275	85	8	int:HNF4A
Interaction	FEV interactions	ARID1B WIZ GPATCH8 ARID1A MGA L3MBTL3 PRRC2B	2.41e-05	203	85	7	int:FEV
Interaction	YWHAZ interactions	KIAA1671 TH HIVEP2 NF1 KIF15 DSG2 MYCBP2 PLEKHG3 PPFIBP1 COBLL1 KCNMA1 HSF1 ARID1A NCKAP5L PABIR2 CEP170B MAP3K5	3.05e-05	1319	85	17	int:YWHAZ
Interaction	RCOR1 interactions	ZZZ3 MYCBP2 FAM169A RNF40 TADA2A MCCC1 NCKAP5L MGA L3MBTL3 ECE2	4.32e-05	494	85	10	int:RCOR1
Interaction	NFIX interactions	BPTF ARID1B ZZZ3 WIZ ARID1A MGA L3MBTL3	4.91e-05	227	85	7	int:NFIX
Interaction	KLF3 interactions	BPTF ARID1B ZZZ3 WIZ TADA2A ARID1A MGA	5.05e-05	228	85	7	int:KLF3
Interaction	CLEC11A interactions	UBQLN2 MYCBP2 CTC1 PATZ1 PRRC2B	5.36e-05	96	85	5	int:CLEC11A
Interaction	TFCP2L1 interactions	BPTF ZZZ3 WIZ ARID1A MGA	6.21e-05	99	85	5	int:TFCP2L1
Interaction	YWHAE interactions	KIAA1671 HIVEP2 NF1 SRSF2 MYCBP2 SAMD11 PLEKHG3 PPFIBP1 COBLL1 KCNMA1 HSF1 NCKAP5L MGA PABIR2 CEP170B MAP3K5	6.23e-05	1256	85	16	int:YWHAE
Interaction	TEAD1 interactions	BPTF ARID1B WIZ ARID1A MGA L3MBTL3	1.01e-04	176	85	6	int:TEAD1
Interaction	TOP3B interactions	TBC1D16 HIVEP3 HIVEP2 SETD1B RARG WIZ MYCBP2 CTC1 KIF26A ZNF398 RNF40 ARID1A LARS2 MED13 CEP170B PRRC2B MAP3K5	1.17e-04	1470	85	17	int:TOP3B
Interaction	SUPT3H interactions	ZZZ3 ATXN7L2 TADA2A MED13	1.28e-04	61	85	4	int:SUPT3H
Interaction	HNF1B interactions	BPTF ARID1B WIZ ARID1A MGA PRRC2B	1.53e-04	190	85	6	int:HNF1B
Interaction	PAX6 interactions	BPTF ARID1B WIZ DSCAM ARID1A MGA L3MBTL3 PRRC2B	1.56e-04	366	85	8	int:PAX6
Interaction	MYOD1 interactions	BPTF ARID1B ZZZ3 WIZ ARID1A MGA	1.71e-04	194	85	6	int:MYOD1
Interaction	PI4KAP2 interactions	GSTCD ECE2	1.74e-04	5	85	2	int:PI4KAP2
Interaction	HSPB2 interactions	ZZZ3 PATZ1 MCCC1 HSF1 MGA EHD4	2.02e-04	200	85	6	int:HSPB2
Interaction	HDAC1 interactions	KIAA1671 BPTF ZZZ3 WIZ KIF15 MYCBP2 RNF20 RNF40 TADA2A MCCC1 HSF1 ARID1A MGA L3MBTL3	2.08e-04	1108	85	14	int:HDAC1
Interaction	C1QTNF4 interactions	UBQLN2 L3MBTL3	2.61e-04	6	85	2	int:C1QTNF4
Interaction	NFIC interactions	TH ARID1B WIZ RNF40 ARID1A MGA	2.63e-04	210	85	6	int:NFIC
Interaction	SCRN2 interactions	UBQLN2 PABIR2 PRRC2B	2.99e-04	31	85	3	int:SCRN2
Cytoband	5q31	PCDHA7 PCDHA4 PCDHA1 PCDHB16	7.08e-05	115	87	4	5q31
GeneFamily	Clustered protocadherins	PCDHA7 PCDHA4 PCDHA1 PCDHB16	4.90e-05	64	57	4	20
GeneFamily	ATAC complex	ZZZ3 TADA2A	7.45e-04	13	57	2	1058
GeneFamily	AT-rich interaction domain containing	ARID1B ARID1A	9.99e-04	15	57	2	418
GeneFamily	Sterile alpha motif domain containing	SAMD11 PPFIBP1 L3MBTL3	2.70e-03	88	57	3	760
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 FAM169A KCNMA1 PGBD5	7.60e-07	161	87	6	4bb7bae54ba3bdf46b525c01f5ad3db8e49819cb
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B GPATCH8 ARID1A ABCC6 MED13	1.76e-06	186	87	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B GPATCH8 ARID1A ABCC6 MED13	1.76e-06	186	87	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	MAGI1 COBLL1 MACROD2 FAM169A ABCC6 MED13	2.18e-06	193	87	6	503a979328c68b096680b71359a26f02fafdff35
ToppCell	droplet-Mammary_Gland-nan-3m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSG2 PLEKHG3 NPAS3 CLIC6 MUC4 CEP170B	2.38e-06	196	87	6	22fcfb713f402ebbd43b2822f0fd919cdbfba6e4
ToppCell	distal-3-Endothelial-Bronchial_Vessel_2\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	MAGI1 ZZZ3 NF1 KIF26A CLEC14A COBLL1	2.53e-06	198	87	6	f701d06e3d7fd2192afae3698c5ec3c355e96da3
ToppCell	normal_Lung-Fibroblasts-Myofibroblasts\|Fibroblasts / Location, Cell class and cell subclass	ZNF469 DSG2 BSN PGBD5 ECE2	1.76e-05	164	87	5	9b4a6007abae992db871d9f6f731d5af724de30d
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	KIAA1671 ARID1B DSG2 PPFIBP1 ABT1	2.21e-05	172	87	5	9dca1542145d88559527db7e0f6ad150df59ca2d
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 HIVEP2 ATXN7L2 MAP4K1 ECE2	2.34e-05	174	87	5	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 WDR93 CRACDL CEP170B PCDHB16	2.47e-05	176	87	5	29cda51a99100ddd2928cadc92da40f001d7e1f4
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 WDR93 CRACDL CEP170B PCDHB16	2.47e-05	176	87	5	01774a86d7d92f31a056b753f9844f923038003e
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 MACROD2 KCNMA1	2.90e-05	182	87	5	a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CARMIL3 SLC38A5 PGBD5 PRRC2B	3.07e-05	91	87	4	25197fde8b9bdaf1e28add695d13aff3ff52d86e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-OPC_related-Oligodendrocyte/OPC\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	CARMIL3 SLC38A5 PGBD5 PRRC2B	3.07e-05	91	87	4	ed4a48e5e5f5d8aadbc7b1b8d84a5f6363a08b85
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	MAGI1 COBLL1 MACROD2 CLIC6 MUC4	3.13e-05	185	87	5	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 MACROD2 KCNMA1	3.30e-05	187	87	5	77886f99c229610abd28c4c370d2c7d1536c9782
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	CRACDL COBLL1 MACROD2 NPAS3 CLIC6	3.38e-05	188	87	5	3cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-neurons_A-Branch_A4_(IN)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIF26A PCDHA1 BSN GPRIN1 ECE2	3.47e-05	189	87	5	cceca3d14dd559bbb2cb4b81ea12c2b62d18ee49
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 MAP4K1 COBLL1 LARS2 MED13	3.74e-05	192	87	5	2de242d81dc085ae734eb7d1f091af9a542e0866
ToppCell	Epithelial\|World / Lineage, Cell type, age group and donor	MAGI1 COBLL1 MACROD2 CLIC6 ABCC6	3.74e-05	192	87	5	499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B MACROD2 FAM169A MED13	3.74e-05	192	87	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 MAP4K1 COBLL1 LARS2 MED13	3.74e-05	192	87	5	ba2a683472a8b785dbf666dc6e94356d879486c3
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6\|TCGA-Prostate / Sample_Type by Project: Shred V9	CEP350 BPTF ARID1A MGA MED13	3.83e-05	193	87	5	abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	BPTF ARID1B MACROD2 FAM169A MED13	3.83e-05	193	87	5	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BPTF TRAF5 ARID1B MYCBP2 COBLL1	3.93e-05	194	87	5	ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell	droplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSG2 CRACDL CLIC6 MUC4 CEP170B	3.93e-05	194	87	5	0ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRAF5 ARID1B COBLL1 MACROD2 L3MBTL3	3.93e-05	194	87	5	9a99abc65e7509e7ae8fb392f5ee4b2a83128072
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 MACROD2 SLC38A5 CLIC6 MUC4	4.12e-05	196	87	5	ed76eeb37400ca154feae9b7ebaddb6c434f8b81
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 PLEKHG3 COBLL1 MACROD2 FAM169A	4.12e-05	196	87	5	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	distal-Epithelial-Club-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	HIVEP2 DSG2 MACROD2 CLIC6 MUC4	4.33e-05	198	87	5	77c7fa7626ea35cb50de9c2f2df637d22e77d3fe
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	MAGI1 ARID1B NF1 MACROD2 KCNMA1	4.43e-05	199	87	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MAGI1 KIF15 ABT1 ARID1A PABIR2	4.54e-05	200	87	5	d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell\|GW13 / Sample Type, Dataset, Time_group, and Cell type.	MAGI1 KIF15 ABT1 ARID1A PABIR2	4.54e-05	200	87	5	3d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial\|5w / Sample Type, Dataset, Time_group, and Cell type.	RARG POMC NPAS3 SLC38A5 ABCC6	4.54e-05	200	87	5	69707f9576d326a06faac49701ef5cd632e760f6
ToppCell	mild-B_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ARID1B PPFIBP1 COBLL1 MACROD2 ATP10D	4.54e-05	200	87	5	222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuroepithelial-Proteoglycan-expressing_cell\|5w / Sample Type, Dataset, Time_group, and Cell type.	RARG POMC NPAS3 SLC38A5 ABCC6	4.54e-05	200	87	5	f94381d0a3b5b81cdbb13b75fc0e4910cbd70382
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KIAA1671 MAGI1 KIF26A CLEC14A EHD4	4.54e-05	200	87	5	90061284a80d29a4ca6078f578e13d32b8cc80e1
ToppCell	droplet-Bladder-nan-3m-Hematologic-bladder_mesenchymal_cell_(Car3+)\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF15 MAP4K1 CCDC88B PCDHB16	2.19e-04	151	87	4	a7b1a60d68f0ed17022fe4c97af64f9f08d39fa3
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP2 CRACDL BSN LARS2	2.41e-04	155	87	4	72a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCell	AT1-AT2_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	WIZ KIF15 DSG2 MUC4	2.60e-04	158	87	4	3bc51cfd37b289cc3e866b54ce55a298e5eff690
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-FB-1\|E18.5-samps / Age Group, Lineage, Cell class and subclass	NEO1 SLC38A5 PCDHA7 PCDHA1	2.66e-04	159	87	4	b4bc888e978b1b577721b891b0af6ba9a1607044
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ATXN7L2 PPFIBP1 FAM169A PCDHB16	2.66e-04	159	87	4	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ATXN7L2 PPFIBP1 FAM169A PCDHB16	2.66e-04	159	87	4	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	Bronchial_Biopsy-Immune-Neutrophils\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	WDR93 ZNF469 ABCC6 ITPKB	2.86e-04	162	87	4	985adca17b0c99563feef7910f3da5df31e636b6
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 MACROD2	2.86e-04	162	87	4	373513f9d0e5007b2e10a8b78d4909dcce9e3b62
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	NEO1 DSG2 PPFIBP1 CRACDL	2.92e-04	163	87	4	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TBC1D16 PATZ1 POMC PABIR2	2.99e-04	164	87	4	d8ecb3de6e34f5f574449e3d2f26fa0b2b7e84e8
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RARG CARMIL3 APMAP MACROD2	2.99e-04	164	87	4	4ade97931ae1780af7836d988fe117a10b3e88a1
ToppCell	Cerebellum-Endothelial-ENDOTHELIAL_STALK\|Cerebellum / BrainAtlas - Mouse McCarroll V32	KIF26A CLEC14A SLC38A5 ABCC6	3.06e-04	165	87	4	7d319a112b9062efee428bef6f4534d2ce782e04
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	ARID1B SETD1B ARID1A MGA	3.13e-04	166	87	4	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP-L5_NP_VISp_Trhr_Cpne7\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KIF26A CLIC6 CCDC88B	3.20e-04	68	87	3	cdb805182f7169fbc3bec31adec3a4e088281757
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	KIAA1671 ARID1B DSG2 ABT1	3.21e-04	167	87	4	7e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_amplifying_undifferentiated_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SAMD11 CLIC6 MED13 PRRC2B	3.28e-04	168	87	4	d69452e2cfeb74023b5cf3d09064d7dcad0008ec
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIF15 MYCBP2 PABIR2 MAP3K5	3.51e-04	171	87	4	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	368C-Myeloid-Dendritic-pDC\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	ZNF469 WIZ COBLL1 SLC38A5	3.51e-04	171	87	4	f3bf5805823d5733b58742172e7668725ce82931
ToppCell	368C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	ZNF469 MAP4K1 COBLL1 SLC38A5	3.51e-04	171	87	4	714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 TRAF5 NF1 DSCAM	3.59e-04	172	87	4	356a66cd9303470e427005cc67fdd22a2c4bf971
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 TRAF5 NF1 DSCAM	3.59e-04	172	87	4	46fadeee483fdf8402df92ec98575a09c6c15b16
ToppCell	facs-Thymus-Flowthrough-3m-Myeloid-macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 TRAF5 NF1 DSCAM	3.59e-04	172	87	4	438d2e7f1897668a14d85ca70722e5d0102606dc
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD4_rest-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SETD1B MAP4K1 L3MBTL3 CEP170B	3.66e-04	173	87	4	1bf9c91c1803a540b5e43bc4280aab4289341cee
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-pericyte_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 WDR93 COBLL1 PABIR2	3.66e-04	173	87	4	3059325901b1e5e12a1a91183f14267288b2f600
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Pericyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D16 WDR93 COBLL1 PABIR2	3.66e-04	173	87	4	36c8338463ee4cc432f568728d55989360f9a68d
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HIVEP3 NEO1 CLEC14A SLC38A5	3.83e-04	175	87	4	282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KIAA1671 KIF26A CLEC14A EHD4	3.91e-04	176	87	4	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	Control-Neuronal_cells-Neuronal_cells\|Control / group, cell type (main and fine annotations)	KIAA1671 MAGI1 PPFIBP1 NPAS3	3.91e-04	176	87	4	98c07d26ba0dc0fe15ca0ea81f633d4591782bd1
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 DSCAM CLEC14A PPFIBP1	3.91e-04	176	87	4	7292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	COBLL1 MACROD2 CLIC6 MUC4	3.91e-04	176	87	4	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	COVID-19-kidney-CD-IC-A\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAGI1 DSCAM DSG2 COBLL1	3.91e-04	176	87	4	45028197364c64e93e3ffe86aff773d47a477d49
ToppCell	Control-Neuronal_cells\|Control / group, cell type (main and fine annotations)	KIAA1671 MAGI1 PPFIBP1 NPAS3	3.91e-04	176	87	4	c29d09ecf0eb17f767d78af4b7f2e7725c967ff8
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	KIF15 MACROD2 SLC38A5 ATP10D	3.91e-04	176	87	4	dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCell	facs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 DSCAM CLEC14A PPFIBP1	3.91e-04	176	87	4	88ca2f83d8301633232735f39b0683efe49d0b86
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 GSTCD CLIC6 MUC4	3.91e-04	176	87	4	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	NEO1 MACROD2 CLIC6 MUC4	4.00e-04	177	87	4	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR93 CARMIL3 PCDHA4 GPRIN1	4.00e-04	177	87	4	9b02fd91c110b405eba6cb74ceb90b1286535973
ToppCell	Control-Myeloid-pDC\|Myeloid / Disease state, Lineage and Cell class	DSG2 CTC1 COBLL1 FAM169A	4.00e-04	177	87	4	e82115bfc32c7b689460fbc5caeb983c1aabe30f
ToppCell	facs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BEST3 BSN MUC4 ITPKB	4.08e-04	178	87	4	fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 MACROD2 CLIC6 ABCC6	4.17e-04	179	87	4	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 CLEC14A PPFIBP1 ITPKB	4.35e-04	181	87	4	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	MAGI1 MACROD2 CLIC6 MUC4	4.35e-04	181	87	4	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Influenza_Severe-B_naive\|World / Disease group and Cell class	TRAF5 PPFIBP1 COBLL1 MACROD2	4.44e-04	182	87	4	e4885a5e6065c9c403cb2d305228691d6ae4ecb6
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 CLEC14A PPFIBP1 ITPKB	4.44e-04	182	87	4	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	E16.5-samps-Endothelial-Immature_fetal_endothelial-Intermediate_Endothelial\|E16.5-samps / Age Group, Lineage, Cell class and subclass	KIAA1671 CLEC14A COBLL1 ITPKB	4.44e-04	182	87	4	fec1caf867b1dc87b24504d895ee1a27df78062e
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	TRAF5 COBLL1 MACROD2 KCNMA1	4.53e-04	183	87	4	818fd886e0188091310825f9145fa53328f2c979
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	MYCBP2 APMAP MCCC1 ABCC6	4.53e-04	183	87	4	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	MAGI1 DSCAM DSG2 COBLL1	4.53e-04	183	87	4	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	TRAF5 COBLL1 MACROD2 KCNMA1	4.53e-04	183	87	4	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	MAGI1 MACROD2 CLIC6 MUC4	4.72e-04	185	87	4	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 MACROD2 CLIC6 ABCC6	4.82e-04	186	87	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CEP350 MAGI1 CLEC14A ITPKB	4.82e-04	186	87	4	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	Control-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 MACROD2 CLIC6 MUC4	4.82e-04	186	87	4	9798428691408e17ff2af2fe2d1b345f074d67e4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIVEP3 FAM169A KCNMA1 GPRIN1	4.82e-04	186	87	4	d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	MAGI1 MACROD2 CLIC6 MUC4	4.82e-04	186	87	4	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 CLEC14A PPFIBP1 EHD4	4.91e-04	187	87	4	3548a9914c2b2f5d805798ce22ab26eab6d03897
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 KCNMA1	4.91e-04	187	87	4	87b3d0478693d4c54ff06b74e5903036b9c1ee6a
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	MAGI1 COBLL1 MACROD2 CLIC6	4.91e-04	187	87	4	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 COBLL1 MACROD2 MCCC1	4.91e-04	187	87	4	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 KCNMA1	4.91e-04	187	87	4	42a1267bfc27b4460b8409ada580a87c4385841c
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIVEP3 CRACDL COBLL1 KCNMA1	4.91e-04	187	87	4	64afdea159f5e67a1e5cea35ce898aae6e80aea5
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial-endothelial_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 CLEC14A PPFIBP1 EHD4	4.91e-04	187	87	4	f4de4b7af1fdfbd628b1f509c060c1079d2e5437
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Endothelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 CLEC14A PPFIBP1 EHD4	4.91e-04	187	87	4	81754e965848b718be20ee97ce072ce426938a69
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF HIVEP2 ZZZ3 SETD1B KIF15 PATZ1 FAM169A APBA3 ARID1A	2.11e-08	173	87	9	4665_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF HIVEP2 ZZZ3 SETD1B WIZ PATZ1 ARID1A MGA ITPKB	2.98e-08	180	87	9	1793_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP3 NF1 SETD1B WIZ PATZ1 COBLL1 ARID1A ITPKB	2.53e-07	167	87	8	3979_DN
Drug	Clidinium bromide [3485-62-9]; Down 200; 9.2uM; MCF7; HT_HG-U133A	HIVEP2 DSCAM PATZ1 PPFIBP1 COBLL1 APBA3 TADA2A ITPKB	8.22e-07	195	87	8	3476_DN
Drug	genistein; Down 200; 10uM; MCF7; HT_HG-U133A	HIVEP2 NF1 RARG PLEKHG3 PATZ1 TADA2A CEP170B ITPKB	9.58e-07	199	87	8	1660_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF SETD1B RARG PLEKHG3 PATZ1 ARID1A ITPKB	3.45e-06	166	87	7	2247_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF RARG PLEKHG3 PATZ1 COBLL1 ARID1A ITPKB	3.45e-06	166	87	7	2268_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF SETD1B RARG PLEKHG3 PATZ1 ARID1A ITPKB	4.37e-06	172	87	7	2330_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	TRAF5 SETD1B RARG PATZ1 ARID1A PRRC2B MAP3K5	5.28e-06	177	87	7	873_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF ZZZ3 KIF15 PATZ1 ARID1A PRRC2B ITPKB	5.47e-06	178	87	7	7245_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF ZZZ3 SETD1B PATZ1 FAM169A ARID1A ITPKB	6.57e-06	183	87	7	7136_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	HIVEP2 ZZZ3 SETD1B PATZ1 APBA3 ARID1A ITPKB	6.81e-06	184	87	7	7555_DN
Drug	Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; MCF7; HT_HG-U133A	MAGI1 HIVEP2 NF1 RARG WIZ DSCAM COBLL1	1.06e-05	197	87	7	3549_DN
Drug	Desipramine hydrochloride [58-28-6]; Down 200; 13.2uM; MCF7; HT_HG-U133A	TBC1D16 NF1 FAM169A ARID1A LARS2 MGA PRRC2B	1.06e-05	197	87	7	5292_DN
Drug	(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; HL60; HT_HG-U133A	MAGI1 CTC1 SLC6A16 COBLL1 APBA3 ARID1A MAP3K5	1.06e-05	197	87	7	3112_UP
Drug	Aminohippuric acid [61-78-9]; Up 200; 20.6uM; HL60; HT_HG-U133A	NEO1 RARG DSCAM PLEKHG3 PPFIBP1 COBLL1 MUC4	1.06e-05	197	87	7	3076_UP
Drug	Etofylline [519-37-9]; Down 200; 17.8uM; MCF7; HT_HG-U133A	HIVEP3 NF1 DSCAM PLEKHG3 GSTCD APBA3 ITPKB	1.10e-05	198	87	7	2256_DN
Drug	Lynestrenol [52-76-6]; Down 200; 14uM; PC3; HG-U133A	PPFIBP1 FAM169A APBA3 ARID1A MGA CEP170B PRRC2B	1.17e-05	200	87	7	1953_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF SETD1B RARG PATZ1 COBLL1 ARID1A	3.84e-05	163	87	6	7453_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF ZZZ3 SETD1B PATZ1 ARID1A ITPKB	3.84e-05	163	87	6	7285_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SETD1B RARG PATZ1 COBLL1 ARID1A ITPKB	3.98e-05	164	87	6	4388_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF SETD1B RARG DSCAM PATZ1 ARID1A	4.11e-05	165	87	6	5625_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF SETD1B RARG PATZ1 ARID1A ITPKB	4.25e-05	166	87	6	7324_DN
Drug	2-methyl-2,2'-bioxirane	GSTCD SLC38A5	4.32e-05	3	87	2	CID000022811
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	TH SETD1B RARG PATZ1 ARID1A ITPKB	4.55e-05	168	87	6	3395_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	BPTF ZZZ3 SETD1B KIF15 PATZ1 ARID1A	4.86e-05	170	87	6	1050_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	HIVEP2 PATZ1 FAM169A KCNMA1 ARID1A ITPKB	5.19e-05	172	87	6	6439_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	BPTF ZZZ3 SETD1B KIF15 PATZ1 ARID1A	5.19e-05	172	87	6	1072_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SETD1B DSCAM PATZ1 TADA2A ARID1A ITPKB	5.19e-05	172	87	6	5903_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	ZZZ3 SETD1B RARG PATZ1 ARID1A ITPKB	5.36e-05	173	87	6	4458_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	HIVEP2 SETD1B PATZ1 COBLL1 ARID1A ITPKB	5.53e-05	174	87	6	7105_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	ZZZ3 SETD1B KIF15 PATZ1 TADA2A ARID1A	5.71e-05	175	87	6	3787_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SETD1B RARG DSCAM PATZ1 ARID1A ITPKB	5.89e-05	176	87	6	7499_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	BPTF TRAF5 SETD1B RARG PATZ1 ARID1A	5.89e-05	176	87	6	981_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	BPTF SETD1B PLEKHG3 PATZ1 ARID1A ITPKB	6.08e-05	177	87	6	6434_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SETD1B RARG PLEKHG3 PATZ1 COBLL1 ARID1A	6.08e-05	177	87	6	3227_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	BPTF ZZZ3 RARG PATZ1 COBLL1 ARID1A	6.27e-05	178	87	6	1112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF HIVEP2 SETD1B KIF15 PATZ1 ARID1A	6.47e-05	179	87	6	4483_DN
Drug	Etoposide [33419-42-0]; Down 200; 6.8uM; MCF7; HT_HG-U133A	HIVEP2 WIZ KIF15 DSCAM APBA3 ITPKB	6.67e-05	180	87	6	5027_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	BPTF SETD1B WIZ PATZ1 ARID1A PRRC2B	6.67e-05	180	87	6	5511_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	HIVEP2 ZZZ3 SETD1B PATZ1 FAM169A ARID1A	6.88e-05	181	87	6	7077_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	CEP350 ZZZ3 RARG ARID1A MGA MED13	7.10e-05	182	87	6	3887_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; PC3; HT_HG-U133A	BPTF TRAF5 ZZZ3 SETD1B FAM169A ARID1A	8.00e-05	186	87	6	6874_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A	BPTF ZZZ3 NF1 SETD1B PATZ1 ARID1A	8.24e-05	187	87	6	6671_DN
Drug	Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	MAGI1 TRAF5 RARG CTC1 MAP3K5 ITPKB	8.49e-05	188	87	6	6451_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP3 NF1 PLEKHG3 COBLL1 NPAS3 ARID1A	9.00e-05	190	87	6	5602_UP
Drug	Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT_HG-U133A	HIVEP3 NF1 WIZ COBLL1 FAM169A ARID1A	1.01e-04	194	87	6	4848_DN
Drug	Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A	CEP350 RARG WIZ GSTCD LARS2 MAP3K5	1.01e-04	194	87	6	2831_DN
Drug	Isradipine [75695-93-1]; Down 200; 10.8uM; MCF7; HT_HG-U133A	TH WIZ DSCAM FAM169A ATP10D PRRC2B	1.04e-04	195	87	6	5447_DN
Drug	Hydrastine hydrochloride [5936-28-7]; Up 200; 9.6uM; PC3; HT_HG-U133A	HIVEP3 RARG WIZ CTC1 TADA2A MAP3K5	1.04e-04	195	87	6	7309_UP
Drug	Methoxy-8-psoralen [298-81-7]; Down 200; 18.6uM; PC3; HT_HG-U133A	NF1 CTC1 PLEKHG3 GSTCD TADA2A ARID1A	1.04e-04	195	87	6	6661_DN
Drug	Acetazolamide [59-66-5]; Up 200; 18uM; MCF7; HT_HG-U133A	CEP350 TH NF1 COBLL1 GSTCD KCNMA1	1.07e-04	196	87	6	1686_UP
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP3 TH HIVEP2 NF1 CTC1 TADA2A	1.07e-04	196	87	6	3872_DN
Drug	Midecamycin [35457-80-8]; Down 200; 5uM; PC3; HT_HG-U133A	HIVEP3 HIVEP2 RARG WIZ PLEKHG3 HSF1	1.07e-04	196	87	6	6745_DN
Drug	Sulpiride [15676-16-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A	TH NF1 DSCAM APBA3 PGBD5 ATP10D	1.10e-04	197	87	6	1467_UP
Drug	Meprylcaine hydrochloride [956-03-6]; Up 200; 14.8uM; MCF7; HT_HG-U133A	TH WIZ DSCAM CTC1 COBLL1 PGBD5	1.10e-04	197	87	6	6204_UP
Drug	Streptomycin sulfate [3810-74-0]; Down 200; 2.8uM; HL60; HG-U133A	NF1 KIF15 GSTCD MED13 CEP170B PRRC2B	1.10e-04	197	87	6	1578_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; PC3; HT_HG-U133A	NF1 RARG PLEKHG3 GSTCD APBA3 CEP170B	1.10e-04	197	87	6	4501_DN
Drug	Fluoxetine hydrochloride [59333-67-4]; Down 200; 11.6uM; MCF7; HT_HG-U133A	CEP350 NF1 COBLL1 TADA2A PGBD5 ITPKB	1.10e-04	197	87	6	3314_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	RARG PATZ1 COBLL1 ARID1A PRRC2B ITPKB	1.13e-04	198	87	6	3332_DN
Drug	(+,-)-Octopamine hydrochloride [770-05-8]; Up 200; 21uM; MCF7; HT_HG-U133A	HIVEP3 TH HIVEP2 NF1 RARG KCNMA1	1.13e-04	198	87	6	5469_UP
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	NF1 DSCAM COBLL1 KCNMA1 APBA3 TADA2A	1.13e-04	198	87	6	4729_DN
Drug	Chlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A	TH HIVEP2 NF1 WIZ PLEKHG3 TADA2A	1.13e-04	198	87	6	3869_DN
Drug	Vitamin K2 [11032-49-8]; Down 200; 9uM; MCF7; HT_HG-U133A	CEP350 HIVEP3 HIVEP2 NF1 WIZ DSCAM	1.13e-04	198	87	6	3880_DN
Drug	Norethindrone [68-22-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A	NF1 SETD1B GSTCD FAM169A HSF1 ARID1A	1.16e-04	199	87	6	7414_UP
Drug	Carbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A	RARG CTC1 SLC6A16 APBA3 TADA2A ARID1A	1.16e-04	199	87	6	5093_UP
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	HIVEP2 NF1 DSCAM CTC1 CEP170B ITPKB	1.16e-04	199	87	6	1648_DN
Drug	Ethynylestradiol 3-methyl ether [72-33-3]; Down 200; 12.8uM; MCF7; HT_HG-U133A	NF1 SETD1B COBLL1 APBA3 PGBD5 MAP3K5	1.16e-04	199	87	6	3346_DN
Drug	CP 154526	TH POMC	1.43e-04	5	87	2	ctd:C101628
Drug	2-methyl-3-phenylpropionamide	TH RARG GSTCD POMC	1.97e-04	75	87	4	CID000348285
Disease	alcohol consumption measurement	C4orf17 MAGI1 TINAG TRAF5 ZZZ3 NF1 KIF26A COBLL1 MACROD2 NPAS3 CLIC6 MGA ECE2	5.39e-05	1242	85	13	EFO_0007878
Disease	Self-injurious behavior	WDR93 ARID1B DSCAM PCDHA4	7.78e-05	78	85	4	HP_0100716
Disease	1,5 anhydroglucitol measurement	PCDHA7 PCDHA4 PCDHA1	7.99e-05	29	85	3	EFO_0008009
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	ARID1B ARID1A	8.15e-05	5	85	2	C3281201
Disease	post-traumatic stress disorder symptom measurement	MACROD2 PCDHA7 PCDHA4 PCDHA1	9.45e-05	82	85	4	EFO_0008535
Disease	3-ureidopropionate measurement	DSCAM L3MBTL3	1.22e-04	6	85	2	EFO_0010641
Disease	Constipation	POMC MED13	1.71e-04	7	85	2	C0009806
Disease	alcohol use disorder (implicated_via_orthology)	ARID1B MAP4K1 KCNMA1 CLIC6 ARID1A	2.56e-04	195	85	5	DOID:1574 (implicated_via_orthology)
Disease	post-traumatic stress disorder	BPTF PCDHA7 PCDHA4 ABT1 PCDHA1	3.01e-04	202	85	5	EFO_0001358
Disease	Heart Diseases	TH RARG BSN	3.20e-04	46	85	3	C0018799
Disease	sexual dimorphism measurement	BPTF TH HIVEP2 NF1 COBLL1 POMC ABT1 BSN ARID1A MGA L3MBTL3	3.29e-04	1106	85	11	EFO_0021796
Disease	Neuroblastoma	TH ARID1B ARID1A	3.41e-04	47	85	3	C0027819
Disease	neuroblastoma (is_implicated_in)	ARID1B ARID1A	3.64e-04	10	85	2	DOID:769 (is_implicated_in)
Disease	total cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement	NF1 SETD1B L3MBTL3	3.86e-04	49	85	3	EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Disease	neutrophil count	HIVEP3 MAGI1 HIVEP2 DSCAM MYCBP2 ZNF398 PCDHA7 PCDHA4 PCDHA1 ARID1A MAP3K5 EHD4	5.90e-04	1382	85	12	EFO_0004833
Disease	juvenile polyposis syndrome (implicated_via_orthology)	HIVEP3 HIVEP2	6.27e-04	13	85	2	DOID:0050787 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	ARID1B ARID1A	6.27e-04	13	85	2	C0265338
Disease	Abnormality of refraction	HIVEP3 DSCAM KCNMA1 GALNTL5 PCDHA7 PCDHA4 PCDHA1 ITPKB	7.23e-04	673	85	8	HP_0000539
Disease	Metabolic Bone Disorder	CTC1 KCNMA1	7.30e-04	14	85	2	C0005944
Disease	triglycerides in small VLDL measurement	BPTF COBLL1 ARID1A	7.36e-04	61	85	3	EFO_0022145
Disease	phospholipids in large VLDL measurement	BPTF COBLL1 ARID1A	7.72e-04	62	85	3	EFO_0022169
Disease	triglycerides in medium LDL measurement	BPTF COBLL1 ARID1A	7.72e-04	62	85	3	EFO_0022322
Disease	Waxy flexibility	TH POMC	8.40e-04	15	85	2	C0233612
Disease	Catalepsy	TH POMC	8.40e-04	15	85	2	C0007370
Disease	Osteopenia	CTC1 KCNMA1	8.40e-04	15	85	2	C0029453
Disease	Drugs used in diabetes use measurement	HIVEP2 NF1 MYCBP2 CLEC14A COBLL1	8.66e-04	255	85	5	EFO_0009924
Disease	triglycerides in small LDL measurement	BPTF COBLL1 ARID1A	8.86e-04	65	85	3	EFO_0022323
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	KCNMA1 POMC ARID1A MUC4	8.98e-04	148	85	4	C0279702
Disease	T-Cell Lymphoma	ARID1A MGA	9.59e-04	16	85	2	C0079772
Disease	Pheochromocytoma, Extra-Adrenal	TH NF1	9.59e-04	16	85	2	C1257877
Disease	Moyamoya Disease	NF1 ABCC6	1.08e-03	17	85	2	C0026654
Disease	Pheochromocytoma	TH NF1	1.36e-03	19	85	2	C0031511
Disease	non-alcoholic fatty liver disease	BPTF COBLL1 KCNMA1 L3MBTL3	1.92e-03	182	85	4	EFO_0003095
Disease	Huntington's disease (is_implicated_in)	HSF1 MAP3K5	1.99e-03	23	85	2	DOID:12858 (is_implicated_in)
Disease	feeling nervous measurement	NF1 DSCAM MGA	2.05e-03	87	85	3	EFO_0009597
Disease	visceral adipose tissue measurement, body mass index	PCDHA7 PCDHA4 PCDHA1	2.05e-03	87	85	3	EFO_0004340, EFO_0004765
Disease	urate measurement, bone density	DSCAM PPFIBP1 ADGRE3 KCNMA1 NPAS3 PRRC2B ITPKB	2.08e-03	619	85	7	EFO_0003923, EFO_0004531
Disease	Hypermetropia, Myopia	HIVEP3 BPTF PPFIBP1 KCNMA1	2.20e-03	189	85	4	HP_0000540, HP_0000545
Disease	Brain Diseases	TH CTC1	2.36e-03	25	85	2	C0006111
Disease	refractive error, age at onset, Myopia	HIVEP3 KCNMA1 GALNTL5 L3MBTL3	2.38e-03	193	85	4	EFO_0004847, HP_0000545, MONDO_0004892
Disease	Parkinson disease	MYCBP2 CTC1 MCCC1 MED13 ITPKB	2.38e-03	321	85	5	MONDO_0005180
Disease	unipolar depression	KIAA1671 TBC1D16 BPTF HIVEP2 ATXN7L2 PCDHA4 ABT1 PCDHA1 MAP3K5 ITPKB	2.43e-03	1206	85	10	EFO_0003761
Disease	Neurodevelopmental Disorders	HIVEP3 ARID1B DSCAM	2.48e-03	93	85	3	C1535926
Disease	Bipolar Disorder	MAGI1 TH DSCAM POMC NPAS3 LARS2	2.58e-03	477	85	6	C0005586
Disease	eye measurement	ZNF469 SRSF2	2.75e-03	27	85	2	EFO_0004731
Disease	glucose tolerance test	CLEC14A COBLL1	2.75e-03	27	85	2	EFO_0004307
Disease	Encephalopathies	TH CTC1	2.75e-03	27	85	2	C0085584

Protein segments in the cluster

Peptide	Gene	Start	Entry
MGSILSPSEKETPPG	BEST3	546	Q8N1M1
GPGPVSTPDNRKEMA	RNF40	551	O75150
NKRAAGEPGTSMPPE	RNF20	6	Q5VTR2
READGTGSPSPAPMR	CCDC88B	1361	A6NC98
APGPATPMLFEKDGS	CTC1	821	Q2NKJ3
ISRSPSGPPAMDLEG	APBA3	6	O96018
PFGGMRKVPGSSEPF	ARID1B	1351	Q8NFD5
MPGFPDNIRPSSSGG	APMAP	301	Q9HDC9
RPPGKEATPGEMVSA	CEP170B	296	Q9Y4F5
LAPGTNPPFMTFDGE	CLIC6	521	Q96NY7
DMAAKAPPGGGTTRT	BPTF	1921	Q12830
APKMTRDTGTAPFAP	COBLL1	826	Q53SF7
PFPMPRGGTQASSEE	ATXN7L2	371	Q5T6C5
QSAGKSGRRPMPGPS	ATP10D	1366	Q9P241
GALRGSPPFEMLSPS	RARG	31	P13631
SPPFEMLSPSFRGLG	RARG	36	P13631
SGEMPPASPSFPRNK	L3MBTL3	601	Q96JM7
SSSMAEGGDLKPPTP	ARID1A	1151	O14497
DPYGSMRKAPGSDPF	ARID1A	1231	O14497
DPGRFSKVSSPAPME	ARID1A	1746	O14497
SGPFSFSVIDKPPGM	DSG2	526	Q14126
GEGPPKTDLMAFSPS	PCDHA7	761	Q9UN72
DDFRMPNGSTIPPGS	MUC4	4846	Q99102
PMSPSPASGLSKGER	MAGI1	806	Q96QZ7
SQGFTPPGMDRSSPD	KCNMA1	966	Q12791
RPVPKLSPEMGSFGS	KIF15	671	Q9NS87
KPEMGSPRALVGGSS	KIAA1671	361	Q9BY89
PPFGGSRTPSTSDMA	NCKAP5L	1286	Q9HCH0
TPDGPLSPGKMEDIS	MGA	1416	Q8IWI9
FSDLEKSPSPTPVMG	PPFIBP1	371	Q86W92
SESPTFSPGKMGPRA	BSN	1486	Q9UPA5
PSFRRKMGTEGSEPG	CARMIL3	1126	Q8ND23
MEVGKGASPFSPGPS	ECE2	41	P0DPD6
AECAPGSGPMFKPTT	GPATCH8	206	Q9UKJ3
PMASPGGSIDERPLS	HSF1	276	Q00613
KPDLSAETPMFPGNG	POMC	51	P01189
PEAASPRKAVGTPMA	KIF26A	881	Q9ULI4
FPGMRIGPEPTTDSF	EHD4	86	Q9H223
PGPNPSTMDSGSGDK	KIAA1191	201	Q96A73
AGMSSEDDGLPRSPP	CRACDL	151	Q6NV74
PAPSPTRGFGKMFVS	PABIR2	116	Q7Z309
SEGPPKTDLMAFSPG	PCDHA1	761	Q9Y5I3
RPPGTSDLGFPLDMT	PATZ1	176	Q9HBE1
SMPEGPFPGRLVDVS	PCDHB16	726	Q9NRJ7
GEGPPKTDLMAFSPS	PCDHA4	761	Q9UN74
FEDTGGPTRKMPPSA	PGBD5	106	Q8N414
GPTRKMPPSASAVDF	PGBD5	111	Q8N414
ARIFGAPPPSESMEG	ABT1	251	Q9ULW3
ESPVRGMSPAPNGAK	C4orf17	91	Q53FE4
EMDGPEGSTKPIRSP	GALNTL5	291	Q7Z4T8
EGSTKPIRSPAMSGG	GALNTL5	296	Q7Z4T8
MAPIPGSKRFSPAGL	CEP350	1311	Q5VT06
NEPKRPMSGEYGPAS	FAM169A	271	Q9Y6X4
GPPPSAIRDMGIKST	MCCC1	151	Q96RQ3
SGKRDPGPSGKADPM	GPRIN1	286	Q7Z2K8
KMDPASSGEGRPVSG	GPRIN1	376	Q7Z2K8
SDPLFIGGPRPTMAK	GSTCD	366	Q8NEC7
SKPRIGSEDASPMGP	CFAP74	1056	Q9C0B2
ASGGPPVSKAPTMDA	nan	501	A6NNC1
PPSPEEKDSGFFMLR	MAP3K5	1031	Q99683
PGEDTPRMPGKSEGS	MACROD2	386	A1Z1Q3
PKFRSPSDEGPGSMG	MAP4K1	401	Q92918
FTASPPKPQDGGRVM	DSCAM	1871	O60469
MSYGRPPPDVEGMTS	SRSF2	1	Q01130
IPFRPKSGDGPMTAS	SLC6A16	686	Q9GZN6
SFTGKGGPPLAMASE	LARS2	486	Q15031
MDRLGPFSNDPSDKP	TADA2A	1	O75478
GGSGMKAPETEPFLR	ABCC6	276	O95255
GPAPGSKPVQFMDFE	SLC38A5	31	Q8WUX1
PPKPSSAGEMSPQRF	PLEKHG3	1001	A1L390
PSAFVRMEKGIPASP	ITPKB	251	P27987
PDLGSDYKPPMSGSN	NEO1	1076	Q92859
GPGPASARPSESKEM	SAMD11	436	Q96NU1
PPDTNSMELGGRPTF	SETD1B	456	Q9UPS6
DGRMPSSSRAESPGP	MYCBP2	2801	O75592
VNSPGFGLDPKTPME	NPAS3	856	Q8IXF0
MREPPGQTTKEPFGG	WIZ	376	O95785
LSSGPSMPFIKEGDG	MED13	951	Q9UHV7
PDPNSSSFKRPDGEM	TRAF5	501	O00463
KMGPDSKPSEGDVFP	ADGRE3	631	Q9BY15
SQPRKESMGPPGLES	CLEC14A	431	Q86T13
MTPFGRPATDLPEAS	ZNF398	306	Q8TD17
PYGGTVEMPSPKSLR	TBC1D16	736	Q8TBP0
LVDPMRPGPSGSFVA	HIVEP3	121	Q5T1R4
ATYSPPMGPVSERKG	NF1	861	P21359
SPYGTLKPEEMSGPG	PRRC2B	1691	Q5JSZ5
MAAPSDGFKPRERSG	EMG1	1	Q92979
DPGTPETGRSGATKM	ZNF469	2351	Q96JG9
SCLFAMPPEVKGPSG	WDR93	361	Q6P2C0
MAENGESSGPPRPSR	UBQLN2	1	Q9UHD9
DGFKFRLGTLPPSPM	TINAG	186	Q9UJW2
SLFAEASDKMSPGPP	HIVEP2	286	P31629
MLPLSDGPEGSSSRP	ZZZ3	621	Q8IYH5
MPTPDATTPQAKGFR	TH	1	P07101