Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	EGF_1	MUC3B LRP1B ITGB4 VWDE ITGB8 TMEFF2 SLIT2 ITGBL1 C6 NOTCH2 SLIT3 LTBP1 MUC3A	1.84e-05	255	231	13	PS00022
Domain	ARM-type_fold	HIP1 DOCK11 TRRAP ITPR2 NCAPD2 UTP20 HECTD1 AGTPBP1 PKP4 UBR4 ARFGEF2 HUWE1 EIF4G1 ATM CTNND2	2.24e-05	339	231	15	IPR016024
Domain	EGF_2	MUC3B LRP1B ITGB4 VWDE ITGB8 TMEFF2 SLIT2 ITGBL1 C6 NOTCH2 SLIT3 LTBP1 MUC3A	2.75e-05	265	231	13	PS01186
Domain	RIH_assoc-dom	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	IPR013662
Domain	Ins145_P3_rec	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	PF08709
Domain	RIH_assoc	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	PF08454
Domain	RIH_dom	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	IPR000699
Domain	Ins145_P3_rcpt	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	IPR014821
Domain	Ryanodine_recept-rel	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	IPR015925
Domain	-	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	1.25.10.30
Domain	RYDR_ITPR	RYR2 ITPR2 ITPR3	3.63e-05	6	231	3	PF01365
Domain	WxxW_domain	CILP MUC5B MUC5AC	3.63e-05	6	231	3	IPR025155
Domain	Mucin2_WxxW	CILP MUC5B MUC5AC	3.63e-05	6	231	3	PF13330
Domain	CTCK_1	SLIT2 MUC5B SLIT3 MUC5AC	6.09e-05	18	231	4	PS01185
Domain	EGF-like_CS	MUC3B LRP1B ITGB4 VWDE ITGB8 TMEFF2 SLIT2 C6 NOTCH2 SLIT3 LTBP1 MUC3A	1.04e-04	261	231	12	IPR013032
Domain	CT	SLIT2 MUC5B SLIT3 MUC5AC	1.40e-04	22	231	4	SM00041
Domain	Integrin_bsu	ITGB4 ITGB8 ITGBL1	1.48e-04	9	231	3	IPR015812
Domain	INTEGRIN_BETA	ITGB4 ITGB8 ITGBL1	1.48e-04	9	231	3	PS00243
Domain	-	AOX1 XDH	1.52e-04	2	231	2	3.30.365.10
Domain	AldOxase/xan_DH_Mopterin-bd	AOX1 XDH	1.52e-04	2	231	2	IPR008274
Domain	Ald_Xan_dh_C	AOX1 XDH	1.52e-04	2	231	2	PF01315
Domain	Fer2_2	AOX1 XDH	1.52e-04	2	231	2	PF01799
Domain	-	AOX1 XDH	1.52e-04	2	231	2	3.90.1170.50
Domain	CO_deh_flav_C	AOX1 XDH	1.52e-04	2	231	2	SM01092
Domain	CO_deh_flav_C	AOX1 XDH	1.52e-04	2	231	2	PF03450
Domain	Mopterin_DH_FAD-bd	AOX1 XDH	1.52e-04	2	231	2	IPR002346
Domain	Ald_Xan_dh_C	AOX1 XDH	1.52e-04	2	231	2	SM01008
Domain	2Fe-2S-bd	AOX1 XDH	1.52e-04	2	231	2	IPR002888
Domain	FAD_binding_5	AOX1 XDH	1.52e-04	2	231	2	PF00941
Domain	Ald_Oxase/Xan_DH_a/b	AOX1 XDH	1.52e-04	2	231	2	IPR000674
Domain	Ald_Xan_dh_C2	AOX1 XDH	1.52e-04	2	231	2	PF02738
Domain	CO_DH_flav_C	AOX1 XDH	1.52e-04	2	231	2	IPR005107
Domain	Ald_Oxase/xanthine_DH	AOX1 XDH	1.52e-04	2	231	2	IPR016208
Domain	-	AOX1 XDH	1.52e-04	2	231	2	1.10.150.120
Domain	EGF	MUC3B LRP1B VWDE ITGB8 TMEFF2 SLIT2 ITGBL1 NOTCH2 SLIT3 LTBP1 MUC3A	1.72e-04	235	231	11	SM00181
Domain	MIR	RYR2 ITPR2 ITPR3	2.10e-04	10	231	3	PF02815
Domain	MIR_motif	RYR2 ITPR2 ITPR3	2.10e-04	10	231	3	IPR016093
Domain	MIR	RYR2 ITPR2 ITPR3	2.10e-04	10	231	3	PS50919
Domain	MIR	RYR2 ITPR2 ITPR3	2.10e-04	10	231	3	SM00472
Domain	Cys_knot_C	SLIT2 MUC5B SLIT3 MUC5AC	2.35e-04	25	231	4	IPR006207
Domain	CTCK_2	SLIT2 MUC5B SLIT3 MUC5AC	2.35e-04	25	231	4	PS01225
Domain	EGF-like_dom	MUC3B LRP1B VWDE TMEFF2 SLIT2 ITGBL1 C6 NOTCH2 SLIT3 LTBP1 MUC3A	2.84e-04	249	231	11	IPR000742
Domain	MOLYBDOPTERIN_EUK	AOX1 XDH	4.53e-04	3	231	2	PS00559
Domain	OxRdtase_Mopterin-bd_dom	AOX1 XDH	4.53e-04	3	231	2	IPR000572
Domain	InsP3_rcpt-bd	ITPR2 ITPR3	4.53e-04	3	231	2	IPR000493
Domain	OxRdtase_Mopterin_BS	AOX1 XDH	4.53e-04	3	231	2	IPR022407
Domain	ARM-like	TRRAP NCAPD2 UTP20 HECTD1 AGTPBP1 PKP4 ARFGEF2 HUWE1 ATAD2 CEP70 CTNND2	5.63e-04	270	231	11	IPR011989
Domain	SEA	TMPRSS15 MUC3B MUC3A	6.15e-04	14	231	3	SM00200
Domain	EGF_3	MUC3B LRP1B VWDE TMEFF2 SLIT2 C6 NOTCH2 SLIT3 LTBP1 MUC3A	7.15e-04	235	231	10	PS50026
Domain	NGF	BDNF NTF3	8.99e-04	4	231	2	PF00243
Domain	Nerve_growth_factor-like	BDNF NTF3	8.99e-04	4	231	2	IPR020408
Domain	Nerve_growth_factor_CS	BDNF NTF3	8.99e-04	4	231	2	IPR019846
Domain	NGF_1	BDNF NTF3	8.99e-04	4	231	2	PS00248
Domain	NGF	BDNF NTF3	8.99e-04	4	231	2	SM00140
Domain	Nerve_growth_factor-rel	BDNF NTF3	8.99e-04	4	231	2	PD002052
Domain	NGF_2	BDNF NTF3	8.99e-04	4	231	2	PS50270
Domain	Nerve_growth_factor-rel	BDNF NTF3	8.99e-04	4	231	2	IPR002072
Domain	VWF_type-D	VWDE MUC5B MUC5AC	9.28e-04	16	231	3	IPR001846
Domain	VWFD	VWDE MUC5B MUC5AC	9.28e-04	16	231	3	PS51233
Domain	Nicotinic_acetylcholine_rcpt	CHRNA2 CHRNA5 CHRNA6	9.28e-04	16	231	3	IPR002394
Domain	VWD	VWDE MUC5B MUC5AC	9.28e-04	16	231	3	SM00216
Domain	VWD	VWDE MUC5B MUC5AC	9.28e-04	16	231	3	PF00094
Domain	Kazal_2	TMEFF2 C6 RECK SLCO6A1	9.84e-04	36	231	4	PF07648
Domain	TSP_1	UNC5B C6 ADAMTSL4 CILP ADAMTS8	1.09e-03	63	231	5	PF00090
Domain	TSP1	UNC5B C6 ADAMTSL4 CILP ADAMTS8	1.25e-03	65	231	5	SM00209
Domain	TSP1_rpt	UNC5B C6 ADAMTSL4 CILP ADAMTS8	1.25e-03	65	231	5	IPR000884
Domain	TSP1	UNC5B C6 ADAMTSL4 CILP ADAMTS8	1.25e-03	65	231	5	PS50092
Domain	KIND_dom	PTPN13 KNDC1	1.49e-03	5	231	2	IPR011019
Domain	KIND	PTPN13 KNDC1	1.49e-03	5	231	2	SM00750
Domain	2Fe2S_fd_BS	AOX1 XDH	1.49e-03	5	231	2	IPR006058
Domain	-	AOX1 XDH	1.49e-03	5	231	2	3.30.43.10
Domain	KIND	PTPN13 KNDC1	1.49e-03	5	231	2	PS51377
Domain	FAD-bd_2_sub1	AOX1 XDH	1.49e-03	5	231	2	IPR016167
Domain	2FE2S_FER_1	AOX1 XDH	1.49e-03	5	231	2	PS00197
Domain	Leu-rich_rpt_Cys-con_subtyp	FBXL4 AMN1 FBXL20	1.56e-03	19	231	3	IPR006553
Domain	LRR_CC	FBXL4 AMN1 FBXL20	1.56e-03	19	231	3	SM00367
Domain	VWC_out	CRIM1 MUC5B MUC5AC	1.56e-03	19	231	3	SM00215
Domain	PIPLC_X_DOMAIN	ACAP1 PLCB4 PLCL1	1.56e-03	19	231	3	PS50007
Domain	PLipase_C_PInositol-sp_X_dom	ACAP1 PLCB4 PLCL1	1.56e-03	19	231	3	IPR000909
Domain	-	TRRAP NCAPD2 UTP20 HECTD1 AGTPBP1 PKP4 ARFGEF2 ATAD2 CTNND2	1.83e-03	222	231	9	1.25.10.10
Domain	SRCR	TMPRSS15 CD163 CD163L1	2.11e-03	21	231	3	PF00530
Domain	2FE2S_FER_2	AOX1 XDH	2.21e-03	6	231	2	PS51085
Domain	-	AOX1 XDH	2.21e-03	6	231	2	3.30.465.10
Domain	DUSP	USP20 USP33	2.21e-03	6	231	2	PF06337
Domain	2Fe-2S_ferredoxin-type	AOX1 XDH	2.21e-03	6	231	2	IPR001041
Domain	DUSP	USP20 USP33	2.21e-03	6	231	2	SM00695
Domain	Fer2	AOX1 XDH	2.21e-03	6	231	2	PF00111
Domain	FAT	TRRAP ATM	2.21e-03	6	231	2	PS51189
Domain	FATC	TRRAP ATM	2.21e-03	6	231	2	PS51190
Domain	FAD_PCMH	AOX1 XDH	2.21e-03	6	231	2	PS51387
Domain	CO_DH_flavot_FAD-bd_sub2	AOX1 XDH	2.21e-03	6	231	2	IPR016169
Domain	FAD-bd_2	AOX1 XDH	2.21e-03	6	231	2	IPR016166
Domain	FAT	TRRAP ATM	2.21e-03	6	231	2	PF02259
Domain	PIK-rel_kinase_FAT	TRRAP ATM	2.21e-03	6	231	2	IPR003151
Domain	FATC_dom	TRRAP ATM	2.21e-03	6	231	2	IPR003152
Domain	PIK_FAT	TRRAP ATM	2.21e-03	6	231	2	IPR014009
Domain	FATC	TRRAP ATM	2.21e-03	6	231	2	SM01343
Domain	-	CHRNA2 CHRNA5 CHRNA6	2.75e-03	23	231	3	1.20.120.370
Domain	Spectrin	SYNE2 DRP2 KALRN	2.75e-03	23	231	3	PF00435
Domain	SEA	TMPRSS15 MUC3B MUC3A	2.75e-03	23	231	3	PS50024
Pathway	KEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	RYR2 ITPR2 ITPR3 CASP3	7.69e-05	19	175	4	M47760
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR2 ITPR3 PLCB4 CASP3	1.41e-04	22	175	4	M47690
Pathway	KEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR2 ITPR3 PLCB4 CASP3	1.41e-04	22	175	4	M47675
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA2 CHRNA5 CHRNA6	1.50e-04	9	175	3	M27597
Pathway	REACTOME_HIGHLY_CALCIUM_PERMEABLE_NICOTINIC_ACETYLCHOLINE_RECEPTORS	CHRNA2 CHRNA5 CHRNA6	1.50e-04	9	175	3	MM15313
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY	ITPR2 ITPR3 PLCB4 CASP3	1.69e-04	23	175	4	M47676
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTSL4 NOTCH2 MUC5B ADAMTS8 MUC3A MUC5AC	1.94e-04	68	175	6	M27303
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY	ITPR2 ITPR3 PLCB4	2.12e-04	10	175	3	M47661
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	CRIM1 LRP1B ITGB8 PTPN13 MIA2 DSCR9 PLAUR DCLK2 JAKMIP1 HECTD1 METAP2 RECK AGTPBP1 VCP NPC1 EXOSC9 KALRN TMEM59 UBR4 ARFGEF2 ADAMTS8 HUWE1 CPNE5 ZNF365 FBH1 ZNF451 EIF4G1 CEP70 CCAR1 ATM CTNND2 USP33 PINK1	1.16e-10	1285	242	33	35914814
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	HK1 TRRAP TASOR2 ITPR3 SYNE2 NCAPD2 UTP20 HECTD1 VCP RANBP2 TUT7 UBR4 NUP98 ELP1 HUWE1 ATAD2 TBL3 EIF4G1 CCAR1 ATM LAS1L	7.81e-09	653	242	21	22586326
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	ZBTB16 DYSF NEK9 SYNE2 ZBTB40 NOCT DNAJB5 NOTCH2 AGTPBP1 VCP RANBP2 KALRN ELP1 ZNF407 CSRP3 AKAP9 MYOM2	9.14e-08	497	242	17	23414517
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	EXT2 GGT7 ITPR3 SLIT2 EIF2B3 NCAPD2 UTP20 HECTD1 VCP NPC1 RANBP2 RARS1 TUT7 TMEM59 UBR4 NUP98 CASP3 ELP1 RHOT2 HUWE1 TBL3 NMD3 EIF4G1	2.24e-07	942	242	23	31073040
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HIP1 ZNF585A MYO7A DYSF TRRAP ITGB4 ITPR2 GGT7 ITPR3 NOD2 EIF2B3 NCAPD2 HECTD1 NOTCH2 RAD9A NPC1 RHBDF2 KALRN CTC1 UBR4 ARFGEF2 RHOT2 HUWE1 BABAM2 EIF4G1	2.71e-07	1105	242	25	35748872
Pubmed	Expression of mucin 3 and mucin 5AC in arthritic synovial tissue.	MUC3B MUC3A MUC5AC	3.33e-07	3	242	3	18163520
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	ERCC3 HK1 PFKM TRRAP NEK9 ANLN EIF2B3 NCAPD2 UTP20 DDX60L METAP2 VCP RANBP2 RARS1 PKP4 TUT7 UBR4 ELP1 SAE1 RHOT2 HUWE1 ATAD2 TBL3 NMD3 EIF4G1 CCAR1 LAS1L	1.01e-06	1353	242	27	29467282
Pubmed	Roundabout receptors are critical for foregut separation from the body wall.	SLIT2 CASP3 SLIT3 CDH2	1.08e-06	12	242	4	23328398
Pubmed	An RNA interference screen uncovers a new molecule in stem cell self-renewal and long-term regeneration.	ITGB4 CD34 CDH3	1.32e-06	4	242	3	22495305
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ITGB4 ITPR3 NCAPD2 CRYBG1 UTP20 HECTD1 DDX60 TUT7 ARFGEF2 EIF4G1	1.71e-06	202	242	10	33005030
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	EED HK1 ATP7A UNC5B CCDC18 EXT2 PFKM ITPR2 ITPR3 USP31 PTPN13 SYNE2 DNAJB5 NOTCH2 AGTPBP1 VCP TMEM126A COX5B PKP4 TMEM59 UBR4 ELP1 TBL3 AKAP9 ZNF451 ATM LAS1L USP33	1.94e-06	1487	242	28	33957083
Pubmed	Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti.	MYO7A BDNF NTF3 CASP3	2.17e-06	14	242	4	21146598
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	HIP1 ERCC3 SRP9 TRRAP GREB1L PTPN13 ANLN NCAPD2 CRYBG1 UTP20 RANBP2 EXOSC9 RARS1 ZNRD2 COX5B CDKN2AIP PKP4 UTP23 ATAD2 BABAM2 TBL3 ZBED6 KCTD3 EIF4G1 CCAR1 CDYL2 CTNND2 LAS1L	2.20e-06	1497	242	28	31527615
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	TRRAP ITPR2 HECTD1 RARS1 NRDC ZNRD2 UBR4 ELP1 NMD3 CCAR1	2.64e-06	212	242	10	33853758
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	TMEFF2 NOD2 ITGBL1 PTPN13 ERICH6 SH3TC2 WDR7 NUP98 SLIT3 AUTS2 CTNND2	2.88e-06	265	242	11	19240061
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	ERCC3 DOCK11 TRRAP ITPR2 ITPR3 HECTD1 RANBP2 EXOSC9 TUT7 NUP98 ELP1 HUWE1 TBL3 LAS1L	2.96e-06	440	242	14	34244565
Pubmed	Methionine sulfoxide reductase B3 deficiency causes hearing loss due to stereocilia degeneration and apoptotic cell death in cochlear hair cells.	MYO7A CASP3 MSRB2	3.29e-06	5	242	3	24191262
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	CRIM1 EXT2 ITGA1 LRP1B ITGB4 NEK9 ITGB8 CHRNA5 BDNF ITPR2 GGT7 MIA2 UTP20 PLAUR HECTD1 NOTCH2 VCP NPC1 TUT7 TMEM59 ARFGEF2 LTBP1 ATM CDH2	4.08e-06	1201	242	24	35696571
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	PFKM NEK9 HECTD1 VCP TBCE RANBP2 RARS1 COX5B UBR4 NUP98 SAE1 HUWE1 TBL3 IGF2BP1 LAS1L	5.93e-06	534	242	15	35032548
Pubmed	Architectural niche organization by LHX2 is linked to hair follicle stem cell function.	ITGB4 CASP3 CD34 CDH3	6.48e-06	18	242	4	24012369
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	HK1 PFKM FBXL4 ITPR2 ITPR3 MIA2 SYNE2 EIF2B3 FGA EXOG TRMT61B VCP TMEM126A COX5B MIS18A TUT7 UBR4 NUP98 ELP1 ZDBF2 RHOT2 HUWE1 TBL3 IGF2BP1 AKAP9 LAS1L USP33	6.50e-06	1496	242	27	32877691
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR2 ITPR2 ITPR3	6.55e-06	6	242	3	25966694
Pubmed	von Willebrand factor D and EGF domains regulate ameloblast differentiation and enamel formation.	VWDE CDH2 CDH3	6.55e-06	6	242	3	34957547
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR2 ITPR2 ITPR3	6.55e-06	6	242	3	20519450
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR2 ITPR2 ITPR3	6.55e-06	6	242	3	23463619
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR2 ITPR2 ITPR3	6.55e-06	6	242	3	16844763
Pubmed	Disrupted Slit-Robo signalling results in membranous ventricular septum defects and bicuspid aortic valves.	SLIT2 NOTCH2 CASP3 SLIT3	8.16e-06	19	242	4	25691540
Pubmed	p600 regulates spindle orientation in apical neural progenitors and contributes to neurogenesis in the developing neocortex.	UBR4 CASP3 CDH2	1.14e-05	7	242	3	24812355
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR2 ITPR2 ITPR3	1.14e-05	7	242	3	11860456
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	MYO7A DOCK11 DYSF TRRAP NCAPD2 FGA PLCB4 COL4A3 CDKN2AIP KIAA0825 CCAR1 MYOM2 ATM GALNT5	1.18e-05	497	242	14	36774506
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	NEK9 NCAPD2 DNAJB5 HECTD1 VCP RANBP2 RARS1 UBR4 NUP98 ELP1 HUWE1 TBL3 IGF2BP1 EIF4G1 CCAR1 LAS1L	1.19e-05	638	242	16	33239621
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	ZSCAN12 DOCK11 NEK9 SYNE2 EXOG PLCL1 JAKMIP1 RANBP2 KALRN ZNRD2 WDR7 PKP4 UBR4 HUWE1 GRM4 AKAP9 EIF4G1 CCAR1 CTNND2 CDH2	1.55e-05	963	242	20	28671696
Pubmed	The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.	PKP4 CTNND2 CDH2	1.82e-05	8	242	3	11821434
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR2 ITPR2 ITPR3	1.82e-05	8	242	3	19033399
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	IFT140 TMPRSS15 DDAH1 CRIM1 MYO7A CCDC18 PRAMEF2 TRRAP NEK9 USP20 CFHR4 DNMT3A THEMIS2 TMEM126A EXOSC9 RARS1 ELP1 RHOT2 ZNF365 AKAP9 TRIM17 LTBP1 USP33	2.19e-05	1242	242	23	30973865
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	PFKM ANLN NCAPD2 RANBP2 EXOSC9 RARS1 UBR4 SAE1 HUWE1 EIF4G1 LAS1L	2.39e-05	332	242	11	32786267
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DDAH1 HK1 MYO7A SCRN1 PFKM LANCL2 ITPR2 USP31 FGA PACS2 DCLK2 PLCL1 METAP2 AGTPBP1 VCP NRDC KALRN WDR7 PKP4 ARFGEF2 ELP1 EIF4G1 KNDC1 CTNND2 CDH2	2.50e-05	1431	242	25	37142655
Pubmed	BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.	ITGB4 CASP3 CD34 CDH3	2.58e-05	25	242	4	23271346
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	RYR2 FSIP2 SYNE2 RANBP2 NUP98 TDRD7 EIF4G1	2.59e-05	123	242	7	26912792
Pubmed	Comparative structure of human neuronal alpha 2-alpha 7 and beta 2-beta 4 nicotinic acetylcholine receptor subunits and functional expression of the alpha 2, alpha 3, alpha 4, alpha 7, beta 2, and beta 4 subunits.	CHRNA2 CHRNA5 CHRNA6	2.71e-05	9	242	3	8906617
Pubmed	Rodent habenulo-interpeduncular pathway expresses a large variety of uncommon nAChR subtypes, but only the alpha3beta4* and alpha3beta3beta4* subtypes mediate acetylcholine release.	CHRNA2 CHRNA5 CHRNA6	2.71e-05	9	242	3	19228980
Pubmed	EZH1 in germ cells safeguards the function of PRC2 during spermatogenesis.	EED ZBTB16 CASP3	2.71e-05	9	242	3	28254491
Pubmed	Purkinje Cell Degeneration and Motor Coordination Deficits in a New Mouse Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay.	BDNF NTF3 CASP3	2.71e-05	9	242	3	28588446
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	PTPN13 ANLN HECTD1 VCP TMEM126A COX5B CDKN2AIP RHOT2 HUWE1 ATAD2 IGF2BP1 LAS1L	2.71e-05	400	242	12	35013556
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	HIP1 HK1 SRP9 PFKM ITPR2 ITPR3 NOD2 SYNE2 EIF2B3 NCAPD2 DDX60L TRMT61B VCP RANBP2 EXOSC9 DDX60 TMEM59 UBR4 ELP1 RHOT2 HUWE1 IGF2BP1 EIF4G1 ATM LAS1L	2.77e-05	1440	242	25	30833792
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	ITPR2 ITPR3 UTP20 DNAJB5 HECTD1 DDX60 COX5B ARFGEF2 SIRT5 NMD3	3.46e-05	285	242	10	32838362
Pubmed	Signalling codes for the maintenance and lineage commitment of embryonic gastric epithelial progenitors.	NOTCH2 CASP3 CDH3 MUC5AC	3.54e-05	27	242	4	32878924
Pubmed	Robo1 modulates proliferation and neurogenesis in the developing neocortex.	SLIT2 NOTCH2 CASP3 SLIT3	3.54e-05	27	242	4	24741061
Pubmed	Slit and Semaphorin signaling governed by Islet transcription factors positions motor neuron somata within the neural tube.	SLIT2 CASP3 SLIT3 CDH2	3.54e-05	27	242	4	25843547
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	HIP1 SRP9 ITPR3 HECTD1 AGTPBP1 VCP ZNRD2 UBR4 HUWE1 BABAM2 TBL3 ZNF451 LTBP1	3.71e-05	481	242	13	28190767
Pubmed	Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.	CHRNA2 CHRNA5 CHRNA6	3.85e-05	10	242	3	20736995
Pubmed	Midbrain-derived neurotrophins support survival of immature striatal projection neurons.	BDNF NTF3 CASP3	3.85e-05	10	242	3	23426664
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	CRIM1 CFHR4 AUTS2 LTBP1	4.11e-05	28	242	4	33953184
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	DDAH1 DOCK11 SYNE2 METAP2 RANBP2 HUWE1	4.62e-05	92	242	6	15840729
Pubmed	Atm deficiency in the DNA polymerase β null cerebellum results in cerebellar ataxia and Itpr1 reduction associated with alteration of cytosine methylation.	ITPR2 ITPR3 DNMT3A ATM	4.74e-05	29	242	4	32123907
Pubmed	The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.	MUC5B MUC5AC	4.82e-05	2	242	2	37146737
Pubmed	MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.	MUC5B MUC5AC	4.82e-05	2	242	2	14988081
Pubmed	Global gene expression analysis reveals a role for the alpha 1 integrin in renal pathogenesis.	ITGA1 COL4A3	4.82e-05	2	242	2	11447218
Pubmed	Patterned expression of BDNF and NT-3 in the retina and anterior segment of the developing mammalian eye.	BDNF NTF3	4.82e-05	2	242	2	10549663
Pubmed	The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.	MUC5B MUC5AC	4.82e-05	2	242	2	17621824
Pubmed	Muc5b is required for airway defence.	MUC5B MUC5AC	4.82e-05	2	242	2	24317696
Pubmed	Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.	MUC5B MUC5AC	4.82e-05	2	242	2	22391959
Pubmed	Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.	MUC5B MUC5AC	4.82e-05	2	242	2	35776514
Pubmed	NOD2/CARD15 on bone marrow CD34+ hematopoietic cells mediates induction of cytokines and cell differentiation.	NOD2 CD34	4.82e-05	2	242	2	19244164
Pubmed	The ocular surface phenotype of Muc5ac and Muc5b null mice.	MUC5B MUC5AC	4.82e-05	2	242	2	24327612
Pubmed	Evaluation of neurotrophic factors and education level as predictors of cognitive decline in alcohol use disorder.	BDNF NTF3	4.82e-05	2	242	2	34341419
Pubmed	Differential influence of BDNF and NT3 on the expression of calcium binding proteins and neuropeptide Y in vivo.	BDNF NTF3	4.82e-05	2	242	2	14625444
Pubmed	Assignment of CD163B, the gene encoding M160, a novel scavenger receptor, to human chromosome 12p13.3 by in situ hybridization and somatic cell hybrid analysis.	CD163 CD163L1	4.82e-05	2	242	2	11124526
Pubmed	Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors.	ITPR2 ITPR3	4.82e-05	2	242	2	8081734
Pubmed	BDNF and CGRP interaction: implications in migraine susceptibility.	BDNF CALCA	4.82e-05	2	242	2	20959432
Pubmed	Multiple transcripts of MUC3: evidence for two genes, MUC3A and MUC3B.	MUC3B MUC3A	4.82e-05	2	242	2	10973822
Pubmed	Altered intracellular localization and valosin-containing protein (p97 VCP) interaction underlie ATP7A-related distal motor neuropathy.	ATP7A VCP	4.82e-05	2	242	2	22210628
Pubmed	Identification of cells in rat brain and peripheral tissues expressing mRNA for members of the nerve growth factor family.	BDNF NTF3	4.82e-05	2	242	2	2206535
Pubmed	Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.	MUC5B MUC5AC	4.82e-05	2	242	2	31030254
Pubmed	Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.	RYR2 ITPR3	4.82e-05	2	242	2	18586264
Pubmed	CGRP inhibits osteoprotegerin production in human osteoblast-like cells via cAMP/PKA-dependent pathway.	CALCA TNFRSF11B	4.82e-05	2	242	2	16611736
Pubmed	Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.	MUC5B MUC5AC	4.82e-05	2	242	2	16540890
Pubmed	Mitochondrial calcium overload is a key determinant in heart failure.	RYR2 ITPR2	4.82e-05	2	242	2	26217001
Pubmed	Brain-derived neurotrophic factor (BDNF) and neurotrophin 3 (NT3) levels in post-mortem brain tissue from patients with depression compared to healthy individuals - a proof of concept study.	BDNF NTF3	4.82e-05	2	242	2	29102768
Pubmed	δ-Catenin Regulates Spine Architecture via Cadherin and PDZ-dependent Interactions.	CTNND2 CDH2	4.82e-05	2	242	2	25724647
Pubmed	Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.	MUC5B MUC5AC	4.82e-05	2	242	2	27435107
Pubmed	Switch of cadherin expression as a diagnostic tool for Leydig cell tumours.	CDH2 CDH3	4.82e-05	2	242	2	23398382
Pubmed	Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.	MUC5B MUC5AC	4.82e-05	2	242	2	26871672
Pubmed	Chromosomal mapping of brain-derived neurotrophic factor and neurotrophin-3 genes in man and mouse.	BDNF NTF3	4.82e-05	2	242	2	1889807
Pubmed	Human and rat brain-derived neurotrophic factor and neurotrophin-3: gene structures, distributions, and chromosomal localizations.	BDNF NTF3	4.82e-05	2	242	2	1889806
Pubmed	Production and characterization of recombinant mouse brain-derived neurotrophic factor and rat neurotrophin-3 expressed in insect cells.	BDNF NTF3	4.82e-05	2	242	2	8113808
Pubmed	Increased pulmonary neurotrophin protein expression in idiopathic interstitial pneumonias.	BDNF NTF3	4.82e-05	2	242	2	18069415
Pubmed	NT-3, BDNF, and NGF in the developing rat nervous system: Parallel as well as reciprocal patterns of expression.	BDNF NTF3	4.82e-05	2	242	2	1688327
Pubmed	Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.	MUC5B MUC5AC	4.82e-05	2	242	2	34656442
Pubmed	Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.	MUC5B MUC5AC	4.82e-05	2	242	2	34058148
Pubmed	Expression of IP3 receptor isoforms at the nodes of Ranvier in rat sciatic nerve.	ITPR2 ITPR3	4.82e-05	2	242	2	17496801
Pubmed	Lingual deficits in BDNF and NT3 mutant mice leading to gustatory and somatosensory disturbances, respectively.	BDNF NTF3	4.82e-05	2	242	2	9118804
Pubmed	Afferent-specific modulation of short-term synaptic plasticity by neurotrophins in dentate gyrus.	BDNF NTF3	4.82e-05	2	242	2	10712646
Pubmed	Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.	RYR2 ITPR2	4.82e-05	2	242	2	28158491
Pubmed	Mucin production during prenatal and postnatal murine lung development.	MUC5B MUC5AC	4.82e-05	2	242	2	21653907
Pubmed	Molecular cloning of a human gene that is a member of the nerve growth factor family.	BDNF NTF3	4.82e-05	2	242	2	2236018
Pubmed	Pancreatic protease activation by alcohol metabolite depends on Ca2+ release via acid store IP3 receptors.	ITPR2 ITPR3	4.82e-05	2	242	2	19528657
Pubmed	Determination of relative amounts of inositol trisphosphate receptor mRNA isoforms by ratio polymerase chain reaction.	ITPR2 ITPR3	4.82e-05	2	242	2	8063813
Pubmed	HIV integration targeting: a pathway involving Transportin-3 and the nuclear pore protein RanBP2.	RANBP2 NUP98	4.82e-05	2	242	2	21423673
Pubmed	Brain-derived neurotrophic factor regulates the onset and severity of motor dysfunction associated with enkephalinergic neuronal degeneration in Huntington's disease.	BDNF NTF3	4.82e-05	2	242	2	15342740
Cytoband	12p13.3	CD163 CD163L1 NCAPD2 IFFO1	1.85e-05	30	242	4	12p13.3
GeneFamily	CD molecules\|Mucins	MUC3B MUC5B MUC3A MUC5AC	3.63e-05	21	166	4	648
GeneFamily	CD molecules\|Integrin beta subunits	ITGB4 ITGB8 ITGBL1	6.13e-05	9	166	3	1159
GeneFamily	Inositol 1,4,5-triphosphate receptors\|Protein phosphatase 1 regulatory subunits	ITPR2 ITPR3	2.50e-04	3	166	2	297
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF132 ZBTB16 ZSCAN12 ZNF585A ZNF585B ZBTB40 PLAG1 ZNF596 ZNF300 ZNF407 ZFP14 ZNF365 ZNF430 ZNF451 ZFP64 PRDM15 ZNF415	3.35e-04	718	166	17	28
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNA2 CHRNA5 CHRNA6	3.90e-04	16	166	3	173
GeneFamily	CD molecules\|Type I classical cadherins	CDH2 CDH3	8.23e-04	5	166	2	1185
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	MYO7A ARFGEF2 AKAP9	2.33e-03	29	166	3	396
Coexpression	GSE37301_LYMPHOID_PRIMED_MPP_VS_CD4_TCELL_DN	ERCC3 DYSF NEK9 CDC7 ITPR2 NOTCH2 THEMIS2 AMBP TMEM59 ATAD2 MSRB2 ATM	3.18e-07	198	240	12	M8859
Coexpression	GSE7768_OVA_ALONE_VS_OVA_WITH_MPL_IMMUNIZED_MOUSE_WHOLE_SPLEEN_6H_UP	HIP1 MYO7A USP20 ANLN NCAPD2 VCP EFL1 PKP4 EIF4G1 PRDM15	7.07e-06	181	240	10	M6857
Coexpression	NAKAYA_MONOCYTE_FLUMIST_AGE_18_50YO_7DY_UP	HIP1 TCP11L1 FBXW2 TRRAP CD163 ITPR2 ZBTB40 PLAUR ADAMTSL4 WDR7 IFFO1 PKP4 UBR4 ARFGEF2 ZFP64 ATM	9.41e-06	477	240	16	M40930
Coexpression	LAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2	ZBTB16 CRIM1 ITGB8 KANK1 PLCB4 SLIT3 AUTS2	1.44e-05	86	240	7	M39248
Coexpression	GSE40274_CTRL_VS_FOXP3_AND_IRF4_TRANSDUCED_ACTIVATED_CD4_TCELL_DN	IFT140 PF4 PLAUR NPC1 CHRNA6 ARFGEF2 PEX26 CEP70 FBXL20	2.15e-05	164	240	9	M9113
Coexpression	VERHAAK_GLIOBLASTOMA_NEURAL	PLCL1 AGTPBP1 COX5B PARP8 LYRM1 SIRT5 MSRB2 USP33	2.45e-05	128	240	8	M2116
Coexpression	BOQUEST_STEM_CELL_UP	SCRN1 LRP1B SLIT2 ITGBL1 PTPN13 C6 RECK NOTCH2 CILP AOX1 SLIT3	3.14e-05	261	240	11	M1834
Coexpression	HAMAI_APOPTOSIS_VIA_TRAIL_UP	TASOR2 ITPR2 PTPN13 ANLN SYNE2 HECTD1 METAP2 AGTPBP1 TUT7 ZNF407 ATAD2 NMD3 TDRD7 ZNF430 CEP70 CCAR1 ATM CTNND2	3.85e-05	656	240	18	M18979
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	CENPW TRIML2 CCDC18 DND1 TASOR2 CDC7 USP31 ANLN CCDC62 TEX101 EIF2B3 FNIP1 DCLK2 NPC1 MIS18A ARFGEF2 HUWE1 CPNE5 ATAD2 NMD3 PAPOLG TDRD7 ZNF451 KCTD3 ATM	3.31e-06	820	230	25	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000	DDAH1 ATP7A SCRN1 TMEFF2 GREB1L SLIT2 PTPN13 ANLN SYNE2 NCAPD2 EXOG RECK NOTCH2 DNMT3A DRP2 KALRN CASP3 ZDBF2 IGF2BP1 CD34 TRIM17 LTBP1 CDH2 CDH3	1.20e-05	827	230	24	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	CENPW TRIML2 CCDC18 DND1 TASOR2 CDC7 USP31 ANLN EIF2B3 UTP20 DCLK2 NPC1 CCDC170 ARFGEF2 DEFB136 CPNE5 ATAD2 NMD3 IGF2BP1 ZNF451 KCTD3 CEP70 ATM	3.24e-05	822	230	23	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500	DDAH1 ATP7A SCRN1 TMEFF2 GREB1L SLIT2 PTPN13 NCAPD2 DRP2 KALRN CASP3 ZDBF2 IGF2BP1 LTBP1 CDH3	5.50e-05	418	230	15	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000	SYNPO2 SCRN1 BDNF RYR2 TMEFF2 USP31 AFP TAFA1 PLAG1 PLCB4 METAP2 AGTPBP1 VCP CALCA CASP3 ARFGEF2 HUWE1 IGF2BP1 AKAP9 ZNF451 CTNND2 CDH2	8.65e-05	818	230	22	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlas	DevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500	ATP7A RNLS DOCK11 RYR2 GREB1L SLIT2 AFP CCDC62 TEX101 SYNE2 FNIP1 DRP2 PKP4 EIF4G1	8.95e-05	387	230	14	gudmap_developingGonad_e16.5_ovary_500
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYNPO2 CRIM1 RYR2 SLIT2 KANK1 PLCL1 CILP KALRN NTF3 TNFRSF11B SLIT3 LTBP1	4.65e-10	186	241	12	4780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	SYNPO2 CRIM1 ITGA1 RYR2 DCLK2 PLCB4 KALRN NTF3 SLIT3 LTBP1 MYOM2	2.74e-09	172	241	11	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNPO2 BDNF RYR2 GREB1L PLCL1 CPNE5 CSRP3 LTBP1 MYOM2 CTNND2 CDH2	5.88e-09	185	241	11	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	SYNPO2 CRIM1 ITGA1 RYR2 SLIT2 ITGBL1 DCLK2 PLCB4 KALRN SLIT3 LTBP1	6.58e-09	187	241	11	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	COVID-19-Heart-CM_+_Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNPO2 BDNF CD163 RYR2 GREB1L PLCL1 CSRP3 MYOM2 CTNND2 CDH2	3.24e-08	170	241	10	3f15242a1d3e4e9871d9170b2ef05842fb609c29
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRP1B RYR2 SLIT2 OTOGL PLCB4 PLCL1 NOTCH2 SLIT3 CDYL2 CDH2	3.24e-08	170	241	10	5570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	SYNPO2 ITGA1 RYR2 DCLK2 PLCB4 KALRN NTF3 LTBP1 MYOM2 CDH2	3.82e-08	173	241	10	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	CV-Severe-7\|CV / Virus stimulation, Condition and Cluster	ANLN NOCT KALRN WDR7 DDX60 NUP98 ZNF407 HUWE1 ZBED6 ZNF415	4.49e-08	176	241	10	3de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNPO2 BDNF RYR2 GREB1L PLCL1 CSRP3 LTBP1 MYOM2 CTNND2 CDH2	5.85e-08	181	241	10	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	SYNPO2 BDNF RYR2 GREB1L PLCL1 CSRP3 LTBP1 MYOM2 CTNND2 CDH2	6.83e-08	184	241	10	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	SYNPO2 DDAH1 CRIM1 ITGA1 RYR2 PLCB4 KALRN NTF3 TNFRSF11B SLIT3	8.36e-08	188	241	10	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	SYNPO2 HIP1 DDAH1 CRIM1 ITGA1 PLCB4 KALRN NTF3 TNFRSF11B SLIT3	8.78e-08	189	241	10	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CRIM1 DYSF USP31 PLCB4 NOCT NTF3 PKP4 EVA1C CD34 CTNND2	1.18e-07	195	241	10	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 LRP1B RYR2 DCLK2 PLCB4 KALRN CPNE5 LTBP1 MYOM2	1.23e-07	196	241	10	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 RYR2 DCLK2 PLCB4 KALRN NTF3 SLIT3 LTBP1 CDH2	1.29e-07	197	241	10	bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 RYR2 ERICH6 KALRN NTF3 ADAMTS8 SLIT3 LTBP1 MYOM2	1.42e-07	199	241	10	b768496381362f9a2706e0892b5a7a0db82e09ce
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HK1 DOCK11 CD163 NOD2 THEMIS2 UBR4 ARFGEF2 ZNF407 ZBED6 IL1RN	1.42e-07	199	241	10	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SYNPO2 DOCK11 ITGA1 SLIT2 KANK1 PLCL1 CILP NTF3 SLIT3 LTBP1	1.49e-07	200	241	10	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SYNPO2 ITGA1 RYR2 DCLK2 PLCB4 PLCL1 KALRN NTF3 LTBP1	4.52e-07	173	241	9	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP7A CRIM1 UNC5B ITGA1 TAFA1 PLCL1 RECK TNFRSF11B CDH2	5.22e-07	176	241	9	f931192e3cc65414e2245354f443473696cc7ce8
ToppCell	droplet-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ATP7A CRIM1 UNC5B ITGA1 TAFA1 PLCL1 RECK TNFRSF11B CDH2	5.22e-07	176	241	9	e2b59a904c5c8f9c88e1e63788e9b6485f22edd0
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	ANLN NOCT KALRN WDR7 NUP98 ZNF407 HUWE1 ZBED6 ZNF415	5.47e-07	177	241	9	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	LV\|World / Chamber and Cluster_Paper	SYNPO2 BDNF TMEFF2 PLCB4 PLCL1 TXNIP MYOM2 CTNND2 CDH2	6.30e-07	180	241	9	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	COVID-19-Heart-CM_3\|Heart / Disease (COVID-19 only), tissue and cell type	DDAH1 BDNF RYR2 DDX60L CSRP3 WDPCP TNFRSF11B CTNND2 CDH2	6.91e-07	182	241	9	287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	SYNPO2 HIP1 CRIM1 ITGA1 PLCB4 KALRN NTF3 TNFRSF11B SLIT3	7.24e-07	183	241	9	818fd886e0188091310825f9145fa53328f2c979
ToppCell	COVID-19-Heart-CM_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNPO2 BDNF RYR2 GREB1L CPNE5 CSRP3 MYOM2 CTNND2 CDH2	7.57e-07	184	241	9	e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	UNC5B ZNF585B ITPR3 FNIP1 DCLK2 TMEM181 DDX60 EVA1C MSRB2	7.92e-07	185	241	9	87151ab95530e70d61328b336518df58db584acb
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	SYNPO2 BDNF RYR2 GREB1L PLCL1 CSRP3 MYOM2 CTNND2 CDH2	7.92e-07	185	241	9	6baccb26f999145e51b91d94315bf8d4655bef31
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|normal_Lung / Location, Cell class and cell subclass	SYNPO2 CRIM1 ITGA1 ITGBL1 NTF3 ADAMTS8 SLIT3 LTBP1 CDH2	9.06e-07	188	241	9	fd70fb89570f014d1299c60fe017dc09f24e57c6
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RNLS ITGB4 ANLN CCDC62 ERICH6 GALNT5 PADI3	9.22e-07	96	241	7	0fc179af7370a29b7bd5d81e1302a479ae72f196
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RNLS ITGB4 ANLN CCDC62 ERICH6 GALNT5 PADI3	9.22e-07	96	241	7	a48235df1f5526ce3ffc4c0c2ba038eb20229c55
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2-Trf\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RNLS ITGB4 ANLN CCDC62 ERICH6 GALNT5 PADI3	9.22e-07	96	241	7	c301ecfd67ece8bb12be1b94b614957a58046457
ToppCell	Cerebellum-Macroglia-OLIGODENDROCYTE-O2\|Cerebellum / BrainAtlas - Mouse McCarroll V32	RNLS ITGB4 ANLN CCDC62 ERICH6 GALNT5 PADI3	9.22e-07	96	241	7	7d402d543ff159c9bb84c00b083e6e18fc0ff786
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	BDNF RYR2 TMEFF2 DDX60L PLCL1 CPNE5 CSRP3 MYOM2 CDH2	9.90e-07	190	241	9	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNPO2 BDNF RYR2 KALRN CSRP3 LTBP1 MYOM2 CTNND2 CDH2	9.90e-07	190	241	9	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Mesenchymal-vascular_smooth_muscle_cell\|World / Lineage, Cell type, age group and donor	SYNPO2 CRIM1 ITGA1 RYR2 KALRN NTF3 SLIT3 LTBP1 MYOM2	1.03e-06	191	241	9	fd89fbc62aa1c73e0f659991e3bd726a0c97bd68
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRP1B ITGB4 PLCB4 C6 NOCT KALRN PKP4 FCRL6 EVA1C	1.08e-06	192	241	9	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZBTB16 ITGA1 RYR2 SLIT2 ITGBL1 AOX1 ADAMTS8 SLIT3 LTBP1	1.08e-06	192	241	9	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	BDNF RYR2 GREB1L PLCL1 CSRP3 WDPCP MYOM2 CTNND2 CDH2	1.13e-06	193	241	9	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	CRIM1 ITGA1 RYR2 SLIT2 ITGBL1 AOX1 ADAMTS8 SLIT3 LTBP1	1.23e-06	195	241	9	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 ZBTB16 ITGA1 RYR2 ITGBL1 KALRN NTF3 SLIT3 LTBP1	1.28e-06	196	241	9	1522958a92e0126326a9f0d9fb1c5b5c50b001ea
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGB4 ITGB8 USP31 ITGBL1 PLCB4 NTF3 IL1RN CDH3	1.28e-06	196	241	9	a58bdf9de05d13d84211e09a933679d485bf8ab4
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 ZBTB16 ITGA1 RYR2 ITGBL1 KALRN NTF3 SLIT3 LTBP1	1.28e-06	196	241	9	1c8294014713684b50885e638668f2ce75f357f0
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 RYR2 PLCB4 KALRN NTF3 SLIT3 LTBP1 CDH2	1.39e-06	198	241	9	bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 DYSF RYR2 DCLK2 PLCL1 KALRN LTBP1 MYOM2	1.39e-06	198	241	9	c12e7511628db819a52959bb68580e27c00c2e41
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 DYSF LRP1B RYR2 DCLK2 PLCL1 LTBP1 MYOM2	1.39e-06	198	241	9	22e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 RYR2 PLCB4 KALRN NTF3 SLIT3 LTBP1 CDH2	1.45e-06	199	241	9	b1753474152b82a0b811b9878c890a359e14919a
ToppCell	Control_saline-Mesenchymal_myocytic-Pericyte-Pericyte_2\|Control_saline / Treatment groups by lineage, cell group, cell type	CRIM1 DOCK11 ITGA1 RYR2 SLIT2 OTOGL NOTCH2 ADAMTS8 CDH2	1.51e-06	200	241	9	bc8949eb34482aca166c4602ff6ab876cb4c2c3c
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNPO2 ITGA1 RYR2 DCLK2 PLCB4 KALRN NTF3 SLIT3 LTBP1	1.51e-06	200	241	9	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	SYNPO2 TMPRSS15 DCLK2 PLCB4 NTF3 LTBP1 MYOM2 CDH2	2.67e-06	160	241	8	d783d29150033e9181c0e30870070268fed3fd85
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SYNPO2 ZBTB16 CRIM1 ITGBL1 OTOGL AOX1 CSRP3 LTBP1	3.51e-06	166	241	8	94636dbc039f794c735960c3425e00bdd5523602
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)\|Thalamus / BrainAtlas - Mouse McCarroll V32	DEFB130B ITGB4 ANLN CSRP3 FCRL6 GALNT5	3.83e-06	77	241	6	4d6e2486dd7702c4e0115567dd0a2c16617816aa
ToppCell	Thalamus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Klk6_(Klk6)-\|Thalamus / BrainAtlas - Mouse McCarroll V32	DEFB130B ITGB4 ANLN CSRP3 FCRL6 GALNT5	3.83e-06	77	241	6	ddd54a5ef6a1fc8be1e852c2192204a749b819c1
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ACAP1 SYNE2 CRYBG1 RANBP2 PARP8 ZNF407 AKAP9 ATM	4.38e-06	171	241	8	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYSF PLPPR1 CD163 C6 CTC1 RASSF10 PPP1R3D ZNF451	4.57e-06	172	241	8	1f335ccb92b22d0412954e8fc3af212f96410b67
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMEFF2 SLIT2 ITGBL1 CCT8L2 CILP AOX1 CD34 LTBP1	4.57e-06	172	241	8	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	DOCK11 ITGB8 PLCB4 TNFRSF11B EVA1C SLIT3 AUTS2 CDH2	4.57e-06	172	241	8	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	droplet-Liver-nan-3m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DYSF PLPPR1 CD163 C6 CTC1 RASSF10 PPP1R3D ZNF451	4.57e-06	172	241	8	bb96c896d125e10b71e94e2bdad243899045af5c
ToppCell	Children_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SYNPO2 ITGA1 RYR2 KALRN NTF3 SLIT3 LTBP1 MUC5AC	4.77e-06	173	241	8	5416b092321c7d9b63f0418c60f2402a138355bf
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5\|TCGA-Pancreas / Sample_Type by Project: Shred V9	ITGB4 ITGB8 BDNF ANLN PLAG1 RHBDF2 CDH3 PADI3	4.97e-06	174	241	8	73e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 ATP7A CRIM1 TAFA1 PLCL1 RECK TNFRSF11B CDH2	5.19e-06	175	241	8	2a53d4f140d5ab096efe8118d8aa351db7838b49
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CENPW OTOGL ANLN NCAPD2 MIS18A PKP4 ATAD2 SLCO6A1	5.19e-06	175	241	8	9142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCell	facs-Lung-3m-Mesenchymal-myofibroblast-pericyte_cell-pericyte\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SYNPO2 ATP7A CRIM1 TAFA1 PLCL1 RECK TNFRSF11B CDH2	5.19e-06	175	241	8	fb91a45763e4c48d993094a13088ffc19f1e2574
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD163 EXOG C6 CTC1 DDX60 FBH1 ZNF451	6.00e-06	127	241	7	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	SYNPO2 ITGA1 RYR2 DCLK2 KALRN NTF3 SLIT3 LTBP1	6.38e-06	180	241	8	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	RV\|World / Chamber and Cluster_Paper	SYNPO2 ZBTB16 PLCL1 WDPCP TXNIP AKAP9 MYOM2 CDH2	6.65e-06	181	241	8	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRIM1 DOCK11 ITGA1 ITGB8 FGA PLCB4 SLIT3 AUTS2	6.65e-06	181	241	8	5f2d3a08577c440c944778d07aa993c6e7873f3d
ToppCell	facs-Lung-Endomucin-24m-Endothelial-Capillary_Aerocyte_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DDAH1 UNC5B SCRN1 TMEFF2 DEFB130A PLAUR CHST1 CD34	6.65e-06	181	241	8	cd81bc307e2bc42c1e9b24d5645ab65fa18c6133
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRIM1 DOCK11 ITGA1 ITGB8 FGA PLCB4 SLIT3 AUTS2	6.65e-06	181	241	8	c7c5f7d4c397b4613c772413a0a679377efffff3
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	SYNPO2 TMEFF2 ZNF585B DCLK2 KALRN SLIT3 LTBP1 LAS1L	6.92e-06	182	241	8	ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RNLS DOCK11 ITGB8 TMEFF2 GREB1L SH3TC2 TNFRSF11B CDH2	6.92e-06	182	241	8	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	ACAP1 HIP1 MYO7A ITGA1 USP20 PACS2 PLAG1 PARP8	6.92e-06	182	241	8	111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 PLPPR1 LRP1B F11 ITPR2 PLCL1 DNMT3A PKP4	6.92e-06	182	241	8	041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 PLPPR1 LRP1B F11 ITPR2 PLCL1 COL4A3 PKP4	7.21e-06	183	241	8	31ab55d5f3639f5964541d5eae23044dbda3356e
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 LRP1B RYR2 OTOGL DRP2 KALRN MUC5B MYOM2	7.50e-06	184	241	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ACAP1 HIP1 MYO7A ITGA1 USP20 PARP8 FCRL6 AUTS2	7.50e-06	184	241	8	e04cabff33a8e36967622ec3e5b37b89afa7e148
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 LRP1B RYR2 OTOGL DRP2 KALRN MUC5B MYOM2	7.50e-06	184	241	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMPRSS15 LRP1B RYR2 OTOGL DRP2 KALRN MUC5B MYOM2	7.50e-06	184	241	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 HIP1 ZBTB16 ITGA1 PLCB4 NTF3 SLIT3 LTBP1	7.80e-06	185	241	8	51dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HIP1 PLPPR1 LRP1B F11 ITPR2 PLCL1 COL4A3 PKP4	7.80e-06	185	241	8	898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 HIP1 ZBTB16 ITGA1 PLCB4 NTF3 SLIT3 LTBP1	7.80e-06	185	241	8	a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 HIP1 ITGA1 BDNF RYR2 PLCB4 SLIT3 LTBP1	8.44e-06	187	241	8	48bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 HIP1 ITGA1 BDNF RYR2 PLCB4 SLIT3 LTBP1	8.44e-06	187	241	8	958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ITPR2 CD163L1 HECTD1 PAPOLG TXNIP AKAP9 ZNF451 ATM	8.44e-06	187	241	8	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	DYSF RYR2 GREB1L CPNE5 LTBP1 MYOM2 CTNND2 CDH2	8.77e-06	188	241	8	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 ITGA1 RYR2 ITGBL1 PLCB4 NTF3 SLIT3 LTBP1	8.77e-06	188	241	8	b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ITGA1 TASOR2 SYNE2 NOCT RANBP2 ZNF407 HUWE1 ZBED6	8.77e-06	188	241	8	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	Striatum-Macroglia-OLIGODENDROCYTE\|Striatum / BrainAtlas - Mouse McCarroll V32	DEFB130B ITGB4 ANLN ADAMTSL4 CSRP3 GALNT5	8.90e-06	89	241	6	ee1dd3571f5914a8274b71f9ca8b36132ae87fe1
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYNPO2 ITGA1 RYR2 SLIT2 KANK1 CILP NTF3 SLIT3	9.12e-06	189	241	8	975e7aa3b862a8b07c2ab8426a14f5cc54998aca
ToppCell	ILEUM-non-inflamed-(1)_T_cell-(1)_CD8_Trm\|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ITGA1 SYNE2 CRYBG1 TMEM181 PARP8 TXNIP AKAP9 AUTS2	9.12e-06	189	241	8	2c8a2fb76ea002bac554bc1c761ce960b5e116e1
ToppCell	critical-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	CENPW ATP7A PLPPR1 ITPR2 DCLK2 PLCL1 TNFRSF11B CDH2	9.48e-06	190	241	8	05a2c3549b68f49081723bf35db14974274419d5
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ATP7A CRIM1 ITGA1 TAFA1 RECK NOTCH2 CDH2 PADI3	9.48e-06	190	241	8	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	SYNPO2 ITGA1 RYR2 SLIT2 ITGBL1 AOX1 SLIT3 LTBP1	9.48e-06	190	241	8	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 ITGA1 SLIT2 ITGBL1 PLCB4 PLCL1 SLIT3 LTBP1	9.48e-06	190	241	8	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SYNPO2 RYR2 SLIT2 KANK1 PLCL1 CILP NTF3 SLIT3	9.48e-06	190	241	8	73d94fbae92029745989a8712eed8b99fd84c193
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SYNPO2 UNC5B ITGA1 ITGBL1 KALRN SLIT3 AUTS2 LTBP1	9.85e-06	191	241	8	107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ZBTB16 ITGA1 RYR2 SLIT2 ITGBL1 AOX1 ADAMTS8 SLIT3	9.85e-06	191	241	8	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	human_hepatoblastoma-Inflammatory_Monocytes\|World / Sample and Cell Type and Tumor Cluster (all cells)	HK1 DOCK11 CD163 CD163L1 PLAUR DDX60L PLCL1 THEMIS2	9.85e-06	191	241	8	3b59bfc6c106ae8a3fbcd4a74bd128c485724921
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	SYNPO2 RYR2 GREB1L KANK1 PLCL1 MYOM2 CTNND2 CDH2	9.85e-06	191	241	8	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGA1 DYSF USP31 PLCB4 NOCT PKP4 CD34 CTNND2	9.85e-06	191	241	8	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
Drug	Proglumide [6620-60-6]; Up 200; 12uM; PC3; HT_HG-U133A	ITPR2 DNAJB5 DNMT3A KALRN IFFO1 PKP4 UBR4 BABAM2 CD34 ATM MUC5AC PHLPP2	1.38e-06	199	239	12	4337_UP
Disease	Nerve Degeneration	BDNF AGTPBP1 NTF3 CASP3 XDH GRM4 CDH2 PINK1	3.28e-07	83	234	8	C0027746
Disease	Malignant neoplasm of breast	ACAP1 ERCC3 DYSF MIA2 OTOGL AFP SYNE2 UTP20 NOTCH2 DNMT3A THEMIS2 KALRN UBR4 NUP98 ARFGEF2 ELP1 XDH ZNF365 AKAP9 ZFP64 ATM GALNT5 CDH2 PADI3	5.44e-06	1074	234	24	C0006142
Disease	pyelonephritis (is_marker_for)	AMBP CALCA IL1RN	1.68e-05	7	234	3	DOID:11400 (is_marker_for)
Disease	diabetic retinopathy (biomarker_via_orthology)	PF4 BDNF SLIT2 CASP3 CD34	2.83e-05	45	234	5	DOID:8947 (biomarker_via_orthology)
Disease	melanoma	ERCC3 MYO7A TRRAP LRP1B CD163L1 CRYBG1 PLCB4 UBR4 PAX4 ATM	3.17e-05	248	234	10	C0025202
Disease	Ataxia	HK1 ATP7A NPC1 RARS1	4.28e-05	25	234	4	C0004134
Disease	xanthinuria (implicated_via_orthology)	AOX1 XDH	6.26e-05	2	234	2	DOID:0060236 (implicated_via_orthology)
Disease	stomach disease (implicated_via_orthology)	CALCA MUC5AC	6.26e-05	2	234	2	DOID:76 (implicated_via_orthology)
Disease	lung large cell carcinoma (is_marker_for)	CHRNA5 PTPN13	6.26e-05	2	234	2	DOID:4556 (is_marker_for)
Disease	TOBACCO ADDICTION, SUSCEPTIBILITY TO (finding)	CHRNA5 BDNF CHRNA6	1.03e-04	12	234	3	C1861063
Disease	Neoplasm Invasiveness	ZBTB16 PLAUR RECK NOTCH2 AMBP ELP1 IL1RN CDH2	1.17e-04	184	234	8	C0027626
Disease	type 1 diabetes mellitus	ACAP1 CENPW RNLS LRP1B ITGB8 BDNF NOTCH2 TNFRSF11B PAX4	1.45e-04	242	234	9	MONDO_0005147
Disease	Major Depressive Disorder	ZBTB16 BDNF KALRN NTF3 XDH CD34 SLIT3 CTNND2 PINK1	1.50e-04	243	234	9	C1269683
Disease	human immunodeficiency virus infectious disease (is_marker_for)	CD163 PLAUR CR2 ATM	1.86e-04	36	234	4	DOID:526 (is_marker_for)
Disease	Grand Mal Status Epilepticus	BDNF NTF3 CASP3 IL1RN CDH2	1.95e-04	67	234	5	C0311335
Disease	Petit mal status	BDNF NTF3 CASP3 IL1RN CDH2	1.95e-04	67	234	5	C0270823
Disease	Complex Partial Status Epilepticus	BDNF NTF3 CASP3 IL1RN CDH2	1.95e-04	67	234	5	C0393734
Disease	Status Epilepticus, Subclinical	BDNF NTF3 CASP3 IL1RN CDH2	1.95e-04	67	234	5	C0751522
Disease	Simple Partial Status Epilepticus	BDNF NTF3 CASP3 IL1RN CDH2	1.95e-04	67	234	5	C0751524
Disease	Non-Convulsive Status Epilepticus	BDNF NTF3 CASP3 IL1RN CDH2	1.95e-04	67	234	5	C0751523
Disease	Status Epilepticus	BDNF NTF3 CASP3 IL1RN CDH2	2.09e-04	68	234	5	C0038220
Disease	pancreatitis (biomarker_via_orthology)	NOD2 FGA CASP3 XDH	2.55e-04	39	234	4	DOID:4989 (biomarker_via_orthology)
Disease	Astrocytosis	ITGA1 ITGB4 BDNF	3.08e-04	17	234	3	C3887640
Disease	Gliosis	ITGA1 ITGB4 BDNF	3.08e-04	17	234	3	C0017639
Disease	pyruvate measurement	PFKM ITGBL1 PACS2 NOCT RHBDF2 KCTD3 CTNND2 CDH2 PRDM15	3.10e-04	268	234	9	EFO_0010117
Disease	neuroblastoma	CRIM1 KALRN NTF3 PARP8 EVA1C ZFP64	3.35e-04	116	234	6	EFO_0000621
Disease	eosinophil count	ZNF585A CCDC18 DYSF PLPPR1 ITGB8 ZNF585B CDC7 ITPR3 ZBTB40 FNIP1 NOTCH2 CCDC170 THEMIS2 SH3TC2 RHBDF2 COX5B PARP8 LYRM1 CSRP3 TNFRSF11B IGF2BP1 AKAP9 CDYL2 ATM MUC5AC	3.46e-04	1488	234	25	EFO_0004842
Disease	Seizures	ATP7A PLPPR1 TRRAP CHRNA5 BDNF FBXL4 PACS2 RARS1	3.71e-04	218	234	8	C0036572
Disease	cutis laxa (is_implicated_in)	ATP7A LTBP1	3.72e-04	4	234	2	DOID:3144 (is_implicated_in)
Disease	end stage renal disease (is_marker_for)	RNLS PLAUR TNFRSF11B IL1RN	4.84e-04	46	234	4	DOID:783 (is_marker_for)
Disease	Paget's disease of bone (is_implicated_in)	VCP TNFRSF11B	6.16e-04	5	234	2	DOID:5408 (is_implicated_in)
Disease	kallikrein-7 measurement	CD163 CD163L1	6.16e-04	5	234	2	EFO_0008195
Disease	neuroticism measurement, cognitive function measurement	CENPW LRP1B TMEFF2 PLCL1 KALRN RASSF10 BABAM2 WDPCP IGF2BP1 KIAA0825 AUTS2 CTNND2 USP33	6.38e-04	566	234	13	EFO_0007660, EFO_0008354
Disease	nevus count, cutaneous melanoma	TASOR2 SYNE2 NOTCH2 ATM CDH3	8.03e-04	91	234	5	EFO_0000389, EFO_0004632
Disease	central corneal thickness	CRIM1 COL4A3 ASB17 ZNF407 CHST1 ADAMTS8 BABAM2 CD34 LTBP1	8.60e-04	309	234	9	EFO_0005213
Disease	lung non-small cell carcinoma (is_implicated_in)	ERCC3 LRP1B CHRNA5 CASP3 ATM IL1RN	8.71e-04	139	234	6	DOID:3908 (is_implicated_in)
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	ATP7A SLIT2 SLIT3	8.81e-04	24	234	3	DOID:3827 (biomarker_via_orthology)
Disease	lung squamous cell carcinoma (is_implicated_in)	CHRNA5 PTPN13 ATM	8.81e-04	24	234	3	DOID:3907 (is_implicated_in)
Disease	Sjogren's syndrome (is_marker_for)	BDNF IL1RN MUC5AC	8.81e-04	24	234	3	DOID:12894 (is_marker_for)
Disease	colorectal cancer (biomarker_via_orthology)	HK1 TXNIP	9.20e-04	6	234	2	DOID:9256 (biomarker_via_orthology)
Disease	age at menarche	HIP1 CENPW LRP1B BDNF GGT7 PLCL1 CCDC170 EEF1AKMT4-ECE2 EFL1 RASSF10 CHST1 SLIT3 EIF4G1	9.92e-04	594	234	13	EFO_0004703
Disease	corneal resistance factor	HIP1 PTPN13 FNIP1 COL4A3 ASB17 ZNF407 CHST1 ADAMTS8 BABAM2 CD34 LTBP1	1.02e-03	451	234	11	EFO_0010067
Disease	Unipolar Depression	ZBTB16 BDNF KALRN NTF3 CD34 SLIT3 CTNND2 PINK1	1.14e-03	259	234	8	C0041696
Disease	Autistic Disorder	TRRAP BDNF PLAUR JAKMIP1 CALCA NTF3 XDH IL1RN	1.20e-03	261	234	8	C0004352
Disease	smoking status measurement, Crohn's disease	NOD2 DNMT3A	1.28e-03	7	234	2	EFO_0000384, EFO_0006527
Disease	keratoconus (is_marker_for)	BDNF FGA	1.28e-03	7	234	2	DOID:10126 (is_marker_for)
Disease	coronary artery disease	IFT140 CENPW RNLS ITGA1 NEK9 VWDE BDNF GGT7 SINHCAF DCLK2 PLCL1 JAKMIP1 NPC1 CDKN2AIP PARP8 ARFGEF2 RASSF10 IGF2BP1 ZBED6 FBXL20	1.42e-03	1194	234	20	EFO_0001645
Disease	serum dimethylarginine measurement	DDAH1 LRP1B PTPN13 ZNF596	1.59e-03	63	234	4	EFO_0005418
Disease	chronic obstructive pulmonary disease (is_implicated_in)	LRP1B CHRNA5 NOD2 IL1RN	1.59e-03	63	234	4	DOID:3083 (is_implicated_in)
Disease	osteoarthritis, knee	BDNF ITPR3 DCLK2 EXOSC9 BABAM2 LTBP1	1.68e-03	158	234	6	EFO_0004616
Disease	Subarachnoid Hemorrhage, Spontaneous	UNC5B CASP3	1.70e-03	8	234	2	C0472383
Disease	osteosarcoma	TASOR2 GRM4	1.70e-03	8	234	2	EFO_0000637
Disease	Subarachnoid Hemorrhage, Intracranial	UNC5B CASP3	1.70e-03	8	234	2	C0795688
Disease	Perinatal Subarachnoid Hemorrhage	UNC5B CASP3	1.70e-03	8	234	2	C0270192
Disease	Subarachnoid Hemorrhage, Aneurysmal	UNC5B CASP3	1.70e-03	8	234	2	C0751530
Disease	rhinitis (is_implicated_in)	BDNF NOD2 IL1RN	1.71e-03	30	234	3	DOID:4483 (is_implicated_in)
Disease	lower face morphology measurement	LRP1B ZBTB40 PLCL1 LTBP1 MYOM2	1.80e-03	109	234	5	EFO_0010948
Disease	interstitial lung disease	PLPPR1 MUC5B FCRL6 MUC5AC	2.00e-03	67	234	4	EFO_0004244
Disease	pulmonary sarcoidosis (is_marker_for)	BDNF NTF3 IL1RN	2.06e-03	32	234	3	DOID:13406 (is_marker_for)
Disease	migraine (is_implicated_in)	KCNK18 CALCA	2.17e-03	9	234	2	DOID:6364 (is_implicated_in)
Disease	Gout	XDH IL1RN	2.17e-03	9	234	2	C0018099
Disease	Subarachnoid Hemorrhage	UNC5B CASP3	2.17e-03	9	234	2	C0038525
Disease	stomach cancer (is_implicated_in)	LRP1B DNMT3A CASP3 IL1RN	2.60e-03	72	234	4	DOID:10534 (is_implicated_in)
Disease	Cryptogenic Tonic-Clonic Epilepsy	BDNF NTF3	2.70e-03	10	234	2	C0751117
Disease	Epilepsy, Tonic-Clonic, Symptomatic	BDNF NTF3	2.70e-03	10	234	2	C0751119
Disease	Epilepsy, Tonic-Clonic, Familial	BDNF NTF3	2.70e-03	10	234	2	C0751118
Disease	Peripheral T-Cell Lymphoma	DNMT3A ATM	2.70e-03	10	234	2	C0079774
Disease	Facies	TBCE DNMT3A	2.70e-03	10	234	2	C0282631
Disease	arrhythmogenic right ventricular cardiomyopathy (is_implicated_in)	RYR2 CDH2	2.70e-03	10	234	2	DOID:0050431 (is_implicated_in)
Disease	dry eye syndrome (is_marker_for)	IL1RN MUC5AC	2.70e-03	10	234	2	DOID:10140 (is_marker_for)
Disease	Tonic-Clonic Epilepsy	BDNF NTF3	2.70e-03	10	234	2	C0014549
Disease	attention deficit hyperactivity disorder, asthma	ITPR3 WDPCP	2.70e-03	10	234	2	EFO_0003888, MONDO_0004979
Disease	acute kidney failure (is_implicated_in)	AMBP IL1RN	2.70e-03	10	234	2	DOID:3021 (is_implicated_in)
Disease	pulmonary tuberculosis (is_marker_for)	CD163 PLAUR IL1RN	2.90e-03	36	234	3	DOID:2957 (is_marker_for)
Disease	colon cancer (is_implicated_in)	LRP1B PTPN13 CASP3	2.90e-03	36	234	3	DOID:219 (is_implicated_in)
Disease	multiple myeloma (is_marker_for)	NOTCH2 RANBP2 XDH	2.90e-03	36	234	3	DOID:9538 (is_marker_for)
Disease	household income	CENPW LRP1B PLCL1 TBCE NPC1 KALRN CDH2 PINK1	3.09e-03	304	234	8	EFO_0009695
Disease	urinary bladder cancer (is_implicated_in)	TMEFF2 XDH MUC5B IL1RN	3.16e-03	76	234	4	DOID:11054 (is_implicated_in)
Disease	Intellectual Disability	HK1 TRRAP BDNF ZBTB40 PACS2 DNMT3A CALCA RARS1 LAS1L CDH2	3.19e-03	447	234	10	C3714756
Disease	cocaine use	DNMT3A CHRNA6	3.29e-03	11	234	2	C3496069
Disease	T-cell acute lymphoblastic leukemia (is_implicated_in)	DNMT3A NUP98	3.29e-03	11	234	2	DOID:5603 (is_implicated_in)
Disease	pulmonary fibrosis	MUC5B MUC5AC	3.29e-03	11	234	2	EFO_0009448
Disease	asthma (is_marker_for)	BDNF AMBP MUC5B IL1RN MUC5AC	3.37e-03	126	234	5	DOID:2841 (is_marker_for)
Disease	Inflammation	BDNF PLAUR CALCA TNFRSF11B IL1RN	3.49e-03	127	234	5	C0021368
Disease	Pulmonary Thromboembolisms	FGA XDH	3.92e-03	12	234	2	C0524702
Disease	autosomal dominant cerebellar ataxia (implicated_via_orthology)	ITPR2 ITPR3	3.92e-03	12	234	2	DOID:1441 (implicated_via_orthology)
Disease	Amelogenesis Imperfecta	ITGB4 PEX26	3.92e-03	12	234	2	C0002452
Disease	Pulmonary Embolism	FGA XDH	3.92e-03	12	234	2	C0034065
Disease	Bronchial Hyperreactivity	CALCA IL1RN	3.92e-03	12	234	2	C0085129
Disease	alcohol drinking	PLCL1 TDRD7 AUTS2 CTNND2	3.98e-03	81	234	4	EFO_0004329
Disease	Global developmental delay	HK1 TRRAP PACS2 RARS1 CDH2	4.25e-03	133	234	5	C0557874
Disease	forced expiratory volume	ZBTB16 CRIM1 ITGA1 ITGB8 CHRNA5 RYR2 ZBTB40 PLAG1 PLCL1 ARFGEF2 DEFB136 ZNF365 CTNND2 FBXL20	4.40e-03	789	234	14	EFO_0004314
Disease	Calcinosis	C6 CTC1 CASP3	4.50e-03	42	234	3	C0006663
Disease	Microcalcification	C6 CTC1 CASP3	4.50e-03	42	234	3	C0521174
Disease	aseptic loosening, revision of total knee arthroplasty	TMEFF2 DCLK2 IL1RN	4.50e-03	42	234	3	EFO_0010725, EFO_0020972
Disease	volumetric bone mineral density	ZBTB40 CCDC170 TNFRSF11B	4.50e-03	42	234	3	EFO_0007620
Disease	Tumoral calcinosis	C6 CTC1 CASP3	4.50e-03	42	234	3	C0263628
Disease	Charcot-Marie-Tooth disease	HK1 SH3TC2 DRP2	4.50e-03	42	234	3	cv:C0007959
Disease	Allodynia	CALCA NTF3 TNFRSF11B IL1RN	4.53e-03	84	234	4	C0458247
Disease	Mechanical Allodynia	CALCA NTF3 TNFRSF11B IL1RN	4.53e-03	84	234	4	C2936719

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKTVENCVCTLRNLS	PKP4	736	Q99569
FVTEKECLQTCRTVA	AMBP	271	P02760
RIIAQKRACDTATCV	CALCA	76	P06881
CDSRIACGKVVRNEL	ERICH6	411	Q7L0X2
REKLCCELRNSSTQT	AKAP9	1671	Q99996
EECGTLKAVIQCLRS	AKAP9	2866	Q99996
LISLKEALCGCTVNI	DNAJB5	266	O75953
SLKRCCNLTDEGVVA	AMN1	121	Q8IY45
CGSGTQRRDIICVSK	ADAMTSL4	926	Q6UY14
IRIDTSCVCTLTIKR	BDNF	231	P23560
RRCVKLTVALETAEC	CTC1	926	Q2NKJ3
IVRLKSGCTCSESIC	CCDC62	546	Q6P9F0
KAGELEKIISRCQVC	COL4A3	1651	Q01955
KCRNIEDICISCGSL	DNMT3A	486	Q9Y6K1
EDICISCGSLNVTLE	DNMT3A	491	Q9Y6K1
IKTAIRCCKALTGID	CCAR1	521	Q8IX12
ETLAICVRGQCVKAG	ADAMTS8	651	Q9UP79
SEVSTAVRICDGCII	EFL1	101	Q7Z2Z2
RGVLKCDISDLSLIC	GRM4	741	Q14833
GKRLIDRIVETICSC	ARFGEF2	111	Q9Y6D5
CQEEACAIILLKRGA	ANKRD18B	111	A2A2Z9
EESRTNACASKCRVI	CENPW	56	Q5EE01
SDCGEKITLCISVLL	CHRNA2	291	Q15822
TVVVDDLRLCTVKLC	ACAP1	306	Q15027
EICACIRLKDGEETT	ACSF2	551	Q96CM8
CEEIQESRKKRGCSS	ATAD2	1101	Q6PL18
VVCRQLECGSAIRVS	CD163L1	726	Q9NR16
RKGIISGSVCQDLCE	DIPK1B	71	Q5VUD6
LFEGRTVQLGKLCCT	AGTPBP1	581	Q9UPW5
TVQLGKLCCTGVETE	AGTPBP1	586	Q9UPW5
KLFIIQACRGTELDC	CASP3	156	P42574
IDSKTVENCVCILRN	CTNND2	756	Q9UQB3
ITESCITEVAAKCGL	AOX1	931	Q06278
CKQELDTETLGTCID	ATP7A	1096	Q04656
VLTCSLETGLTCKNE	MUC5B	1846	Q9HC84
TTCSDVVRVLLEDGC	RASSF10	26	A6NK89
SVCLVRNEASATKCI	RANBP2	1731	P49792
EESSKRGLLRVTLCC	PATE4	76	P0C8F1
EKTVEKCCISLNGRS	RAD9A	91	Q99638
SRGSIICKSDCVEIL	RECK	426	O95980
EILKTTCFICGLERD	ITPR2	2556	Q14571
EEILKTTCFICGLER	ITPR3	2531	Q14573
ITIVTREKTISCNGC	OR6C70	81	A6NIJ9
QGQRCTIDIDECISK	NOTCH2	866	Q04721
CLSKICRDVQKTLGL	PLA2G12A	131	Q9BZM1
IKVTSLCSRIEQIQC	NUP98	1721	P52948
TELRKTNDINCCLSI	PARP8	91	Q8N3A8
CRILNCSETVVEDRK	KCNK18	66	Q7Z418
ILLEDNRCVTKNSSC	LRP1B	2496	Q9NZR2
TGIKCAGIDVRLCDV	METAP2	286	P50579
EIRANLVEACCKVAT	KIAA0825	511	Q8IV33
LVEACCKVATAVLQR	KIAA0825	516	Q8IV33
KLDVIKSGCSARQVC	NEK9	361	Q8TD19
EVDCCTTLQLSNGKR	NLRP11	291	P59045
TITVKGAIENCCRAE	IGF2BP1	326	Q9NZI8
TLVSQCRDTLCVTKN	ANLN	1071	Q9NQW6
LSTGKRETECVLKSC	CFAP57	541	Q96MR6
DAKTCLVLCSRVLSV	ASB17	206	Q8WXJ9
LCAGLIAVSCLTIKE	TMPRSS15	31	P98073
RSDCESQECVTKLLQ	LANCL2	166	Q9NS86
SSQESIVCELRCKSV	CDKN2AIP	496	Q9NXV6
VVKRLCTLDGKQVTC	DCLK2	241	Q8N568
IDGDSLLITCICEIS	DDX60	41	Q8IY21
GSDIQRVLCVTSCSL	DDX60L	256	Q5H9U9
GRKDSSIICAEVRCL	FCRL6	391	Q6DN72
IIQNCVTSGCKILSE	FSIP2	6101	Q5CZC0
RNSKCIDTESLCVVA	EXOSC9	111	Q06265
AATLLANRLTEKCCV	PINK1	536	Q9BXM7
SCRQDGLTVIVTACL	GGT7	101	Q9UJ14
LEDKSVCQRGDCINT	LTBP1	1166	Q14766
TRLRCVTKCTSGVDN	MUC3A	3171	Q02505
LNTICTTCDRIKQSA	PFKM	546	P08237
VKCSLCVVGIQALAE	PEX26	81	Q7Z412
KRIVGCICEEDNTSV	COX5B	86	P10606
SQRRSIKDCLSTCEQ	FAM214A	761	Q32MH5
TCLLGDTVILQCKVC	KALRN	2481	O60229
ISGLERSQEKSQDCC	AUTS2	271	Q8WXX7
NLKEVRSIGCGDCSV	KANK1	621	Q14678
CVLAELKGVTCENRE	LAS1L	306	Q9Y4W2
GDLILSKSCENAIVC	EED	316	O75530
AAVDGVIISLCCNSK	ELP1	551	O95163
RTSDIRNICSVDTCK	EXOG	286	Q9Y2C4
LEVRDSICCKLSNGA	JAKMIP1	601	Q96N16
RRCGLTDSETCLKSV	MUC5AC	476	P98088
ESKSQCIEGISRLIC	PACS2	826	Q86VP3
IINGCCCLEEKVRSL	PADI3	606	Q9ULW8
RGTILDCNTCKFATI	ITGA1	1056	P56199
RIDTSCVCALSRKIG	NTF3	241	P20783
STCDDSILVKTVCGV	HK1	811	P19367
VVICASKIRGNEFCV	GREB1L	556	Q9C091
CQAVAGVCKSILTLS	HUWE1	821	Q7Z6Z7
ICDVCTCELQKEVRS	ITGB4	451	P16144
CDISRILKVSNGCVS	PAX4	41	O43316
CRRIDITAKLCDVAQ	IFFO1	331	Q0D2I5
VSLCCDVRQLQTLKD	NPC1	71	O15118
ERCDIVSNLISKGCS	ITGB8	81	P26012
CIRSLNGCRVTDEIL	PAPOLG	196	Q9BWT3
GVCRDKLCSTLDDTI	DEFB130B	36	P0DP73
KLCSTLDDTIGICNE	DEFB130B	41	P0DP73
ISCCRNVTEDKLILG	WDPCP	341	O95876
TCLTEACIRVAGKIL	EEF1AKMT4-ECE2	211	P0DPD8
GSSCLIKDRVTITNC	EIF2B3	376	Q9NR50
LTLCALVIRESCAKD	EVA1C	336	P58658
SDCGEKVTLCISVLL	CHRNA6	266	Q15825
SNEGEKICLCTSVLV	CHRNA5	276	P30532
LRCLTEVALCQDKRS	ATM	456	Q13315
EQCVKVLELICTRES	HECTD1	121	Q9ULT8
ILSNCGIEKESDLCV	FBH1	276	Q8NFZ0
LTSNVLKTGVVRCCV	FBH1	951	Q8NFZ0
CKVAACEATGRQLLT	CR2	466	P20023
QGCIEEQCKRRTILT	DOCK11	1876	Q5JSL3
ATNCLRITDLKSGCT	BABAM2	31	Q9NXR7
SSLCVLVSTVGKLCR	CEP70	516	Q8NHQ1
EKTLNICEVGTIRCA	C6	906	P13671
RKRKQEGTENTSICC	DSCR9	106	P59020
IGCCEANKLVISELR	CCDC18	431	Q5T9S5
TDKVCSICLSRRQQV	CDC7	356	O00311
KVCGSELVRLELSCS	FBXL4	371	Q9UKA2
KCISIENTTVILEDC	GALNT5	821	Q7Z7M9
RTCFDAKLETVVCTG	FNIP1	671	Q8TF40
TEELCSERKQGCTLN	CRIM1	501	Q9NZV1
VSGECVTQLLKDTCF	F11	16	P03951
CLRTCSKSDIEIENG	CFHR4	331	Q92496
SLECLCRLLTTIGKD	EIF4G1	931	Q04637
VDIDIKIRSCRGSCS	FGA	171	P02671
KQCIDECTARIEIGL	LYRM1	61	O43325
VCRSTEKCELSVDGL	DND1	131	Q8IYX4
EEKLQLTSSCRVCRS	KNDC1	176	Q76NI1
CLSCVKSGDETRLQL	IL1RN	91	P18510
VTCACLKDVTTGQER	CCDC170	691	Q8IYT3
GVCRDKLCSTLDDTI	DEFB130A	36	P0DP74
KLCSTLDDTIGICNE	DEFB130A	41	P0DP74
VTAACTVRKRCLVLG	ERCC3	351	P19447
KCRIAEDCCLTIVGS	CRYBG1	1636	Q9Y4K1
RCAICGKSLESTNVT	CSRP3	146	P50461
DGVKVRTCTSQKAVC	DEFB136	26	Q30KP8
IGREINCKCLKTLSV	FBXW2	306	Q9UKT8
AASVLCRELQCGTVV	CD163	511	Q86VB7
RDSIEVCLLSICGQL	RYR2	2566	Q92736
VVGQCTIRSLESFLC	DYSF	1416	O75923
CVKTQRLDVAKVCLG	IFT140	811	Q96RY7
CTLSAEESIRKCQGS	ITGBL1	316	O95965
SSTGKRICEIQAVDC	KCTD3	516	Q9Y597
NKEQLTVIRATVCDC	CDH3	626	P22223
SNISILRVKVCQCDS	CDH2	691	P19022
KCSGIREVKLTQGIC	CD34	176	P28906
EKVDGLLTCCSVLIN	DDAH1	266	O94760
LECKESGRQFCIAVT	NOCT	271	Q9UK39
VDICQTCFLTGRASK	DRP2	631	Q13474
KCGTIILSAEELSNC	CPNE5	161	Q9HCH3
ECCKLTTLERGQCII	AFP	301	P02771
LNLREDCVCKVGTIL	OTOGL	1836	Q3ZCN5
GQRLELTCDTKTICK	PTPN13	581	Q12923
SCLISEQKSISVAGC	OR6K6	111	Q8NGW6
KCGDLECEALINRVS	MIA2	31	Q96PC5
LVEATRLRCVTKCTS	MUC3B	1081	Q9H195
SLTAEIDRLKNCGCL	RARS1	21	P54136
NRIEERSQTVKCSCL	TAFA1	56	Q7Z5A9
IGEKVCLEVSSCLSL	TCP11L1	396	Q9NUJ3
NCCESSEQIKRLLET	UTP20	311	O75691
ETQLCTTRCVLKELE	UTP23	56	Q9BRU9
ICQESLKEAVSTNCG	TRIM40	16	Q6P9F5
RIVCVCSGTDLVNIS	PLCB4	96	Q15147
LNTGDLDCETCTITR	TMEM126A	91	Q9H061
CTENDGICLLKIVSA	SYNE2	3431	Q8WXH0
LRIGDTVTCVCQFKC	TMEFF2	81	Q9UIK5
CKQQSEILVVSEGSC	TMEFF2	121	Q9UIK5
IETCVECSAKNLRNI	RHOT2	141	Q8IXI1
CGTCEKTFRIESALE	PRDM15	801	P57071
CLQITDEGLITICRG	FBXL20	231	Q96IG2
KLEVNERILGCCTSL	HIP1	816	O00291
DICEEIKVVSGCQSS	SLCO6A1	206	Q86UG4
RCSLLALGSDKQTEC	SH3TC2	346	Q8TF17
LTCCSRDVIVKVDQI	SAE1	131	Q9UBE0
ETVCTGCATAILRAL	CCT8L1P	66	A6NM43
ETVCTGCATAILRAL	CCT8L2	66	Q96SF2
LRDSVLNCSDCSIKV	TDRD7	791	Q8NHU6
TCGNLLEEDLKCLSQ	PRAMEF2	301	O60811
SLIAQEKTILTGECC	PLPPR1	101	Q8TBJ4
AAEKVTEGVRCICSQ	SCRN1	176	Q12765
TEGVRCICSQLSLTT	SCRN1	181	Q12765
CSAVVLEESKCLVRS	CDYL2	451	Q8N8U2
EKRSEEKRILVCGTC	C21orf62-AS1	56	Q17RA5
EKRILVCGTCGTRSS	C21orf62-AS1	61	Q17RA5
VQNCCGISKTEEREI	CILP	451	O75339
CVRKCGLLNLTVAAE	CHST1	181	O43916
DASVGTIQCLEEILC	NCAPD2	726	Q15021
TSGDLTCKVCLQTFE	PLAG1	146	Q6DJT9
TCKVCLQTFESTGVL	PLAG1	151	Q6DJT9
ETRSGDICNACVLLV	SINHCAF	46	Q9NP50
CEGTIVDCSNQKLVR	SLIT3	511	O75094
TRLFCDVDQITLCSK	TRIML2	26	Q8N7C3
RVTIEVTVKSCDCLN	VWDE	1171	Q8N2E2
LCRELSDLVSICKSV	PLCL1	581	Q15111
ECIQCGKAFSERSTL	ZNF132	656	P52740
VVCGKVCDDSGVIRL	ZNF451	501	Q9Y4E5
GIDLNRTKLECESAC	TMEM59	86	Q9BXS4
STQKCGIDVTLCEEA	TNFRSF11B	191	O00300
VEECALGQDLCRTTI	PLAUR	36	Q03405
REITLECRVCGKTFS	ZNF596	191	Q8TC21
KSESRTIGEQCSVCG	ZBTB16	396	Q05516
DGIRTCELALSCEKI	TRMT61B	371	Q9BVS5
VILDCSDRQKTEGCR	SYNPO2	286	Q9UMS6
SLGSARTEVVCKQCE	MSRB2	136	Q9Y3D2
SKREKENGCVLETLC	MIS18A	126	Q9NYP9
NISDRGICKLIECAL	NOD2	826	Q9HC29
ERLVVLCGTCLIVSS	PHLPP2	171	Q6ZVD8
CQRACKLAIRESIES	VCP	691	P55072
EVSLRNCAVSCAGEK	TBCE	131	Q15813
GCITSALCVLEALKN	RNLS	326	Q5VYX0
RTRTLTCAGKCAEII	TMEM181	256	Q9P2C4
TVCCSRLKESFLVTG	TBL3	426	Q12788
ECCLSTGDLIKVTQV	THEMIS2	41	Q5TEJ8
KTCVSSLCVNKEERG	FAM170A	111	A1A519
CTNLSEGVLSVRKRC	EXT2	286	Q93063
VETCDKGALCQETIL	TEX101	51	Q9BY14
TVKDISCINTECIDI	ZDBF2	1556	Q9HCK1
KIQSREKSSICTECG	ZNF585B	346	Q52M93
TVAAVCATRRKLCEA	NRDC	6	O43847
LVCLERVTCSDLGIS	PPP1R3D	176	O95685
IRNACVDKFTTLCVT	XDH	1306	P47989
CQTTKKVSRLECRGG	SLIT2	1471	O94813
LASTELTCKICVRQV	UNC5B	801	Q8IZJ1
DGDLQCLCVKTTSQV	PF4	36	P02776
GSILSLVQCLTCDRV	USP20	451	Q9Y2K6
KVQSREKSSICTECG	ZNF585A	346	Q6P3V2
TSIQLCGLIRACAEA	ZNRD2	176	O60232
LARKLQEEATCSICL	TRIM17	6	Q9Y577
EDLQLRTGCKSVDEC	ZNF430	141	Q9H8G1
CVTGLAKDCLITNIL	ZBED6	526	P86452
ICSSLLTQEQKSCIR	ZNF415	246	Q09FC8
GNLCVKVTDDLVCLV	SRP9	36	P49458
RDVVLNTLAESCCGL	ZNF365	101	Q70YC4
SCSRIVLSCDDSVKI	TASOR2	731	Q5VWN6
CEECGKAFRLLSQLT	ZFP14	426	Q9HCL3
AELSKGESVCLDRCV	TIMM10	41	P62072
AGSDKIVLLVCNRAC	USP31	451	Q70CQ4
SCTIGNVDTVLKCSI	ZNF407	176	Q9C0G0
CEVTRVKAVRILACG	TXNIP	36	Q9H3M7
VVCREKQSGLLCKVS	TUT7	396	Q5VYS8
LFKTRCTSCGVVAEN	SIRT5	161	Q9NXA8
LCTGCSRLDRTEIIT	UBR4	136	Q5T4S7
SGCIQTQRKDCSETL	RHBDF2	506	Q6PJF5
RTVLILAVCCGSASI	POTEM	306	A6NI47
VSDGRCIEFTKLACT	WDR7	96	Q9Y4E6
CDVCEKAFIQRTSLT	ZSCAN12	471	O43309
FQVTDCRSLVKTLVC	TRRAP	541	Q9Y4A5
VAKIVTQRAFRCETC	ZFP64	571	Q9NTW7
TRDGSLCSILKVCQG	ZNF300	116	Q96RE9
GTIISSVQCLTCDRV	USP33	481	Q8TEY7
ICKSGTSVKIECRSL	TRBV20-1	26	A0A075B6N2
EFLTGTEKRVILNCC	ZBTB40	381	Q9NUA8
KRNSRDQCCIISGES	MYO7A	146	Q13402
TICRVCAKRVSTQED	MYOM2	66	P54296
ICVACLRSKVDISQG	NMD3	31	Q96D46