Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesscell morphogenesis involved in neuron differentiation

GFRA3 DIP2A PLXNB1 NOTCH3 HSPG2 SEMA4B APBB1 APC TRIOBP LAMA5 SLITRK3 RET EFNA2 PLXNC1 SCRIB MARK2 GOLGA8A TNR CDH1 AGRN NEUROG3 EPHA10

4.19e-0674820122GO:0048667
GeneOntologyBiologicalProcessaxon development

GFRA3 PLXNB1 NOTCH3 HSPG2 SEMA4B APBB1 APC LAMA5 SLITRK3 RET EFNA2 PLXNC1 MARK2 RTN4RL2 GOLGA8A TNR CDH1 AGRN NEUROG3 EPHA10

5.06e-0664220120GO:0061564
GeneOntologyBiologicalProcessaxonogenesis

GFRA3 PLXNB1 NOTCH3 HSPG2 SEMA4B APBB1 APC LAMA5 SLITRK3 RET EFNA2 PLXNC1 MARK2 GOLGA8A TNR CDH1 AGRN EPHA10

1.16e-0556620118GO:0007409
GeneOntologyBiologicalProcessneuron projection development

DLG5 GFRA3 ITPR1 DIP2A DENND5A PLXNB1 NOTCH3 HSPG2 SEMA4B FOXO6 APBB1 APC TRIOBP LAMA5 SLITRK3 RET EFNA2 TRIM67 PLXNC1 SCRIB MARK2 RTN4RL2 GOLGA8A TNR CDH1 AGRN NEUROG3 EPHA10 OTOG

2.06e-05128520129GO:0031175
GeneOntologyBiologicalProcessregulation of cell adhesion

DLG5 CD164 JAG2 PKD1 HRG PLXNB1 CASS4 HSPG2 RC3H2 ZC3H12A APC TRIOBP LAMA5 RET TSPAN32 TESK1 SLC9A1 PLXNC1 SPRY4 CHRD SCRIB TNR CDH1

3.83e-0592720123GO:0030155
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

DLG5 CD164 HRG PLXNB1 HSPG2 RC3H2 ZC3H12A TSPAN32 PLXNC1 SPRY4 SCRIB TNR CDH1

8.41e-0537520113GO:0007162
GeneOntologyBiologicalProcessaxon guidance

GFRA3 NOTCH3 HSPG2 SEMA4B APBB1 LAMA5 RET EFNA2 TNR AGRN EPHA10

1.17e-0428520111GO:0007411
GeneOntologyBiologicalProcessneuron projection morphogenesis

GFRA3 DIP2A PLXNB1 NOTCH3 HSPG2 SEMA4B APBB1 APC LAMA5 SLITRK3 RET EFNA2 PLXNC1 MARK2 GOLGA8A TNR CDH1 AGRN NEUROG3 EPHA10

1.18e-0480220120GO:0048812
GeneOntologyBiologicalProcessneuron projection guidance

GFRA3 NOTCH3 HSPG2 SEMA4B APBB1 LAMA5 RET EFNA2 TNR AGRN EPHA10

1.20e-0428620111GO:0097485
GeneOntologyCellularComponentcell surface

FAM234A ENPP3 CRLF2 GFRA3 DIP2A FCRL3 PKD1 HRG TREML1 NOTCH3 CNTFR RC3H2 SLITRK3 IL17RC TSPAN32 TF COL23A1 TGFBR1 SLC9A1 CHRD FCRL4 RTN4RL2 TNR CDH1 AGRN DCBLD2

3.25e-05111120426GO:0009986
GeneOntologyCellularComponentextracellular matrix of synaptic cleft

LAMA5 TNR

2.82e-0432042GO:0098965
GeneOntologyCellularComponentScrib-APC-beta-catenin complex

APC SCRIB

2.82e-0432042GO:0034750
MousePhenoosteosclerosis

AMER1 HIVEP3 NCOR2 LTBP3

1.51e-05141604MP:0005422
DomainVWC_out

CRIM1 SSPOP JAG2 MUC5B MUC2 OTOG

3.28e-08191996SM00215
DomainVWF_dom

CRIM1 SSPOP JAG2 MUC5B CHRD MUC2 OTOG

2.76e-07421997IPR001007
DomainVWFC_1

CRIM1 SSPOP JAG2 MUC5B CHRD MUC2

2.02e-06361996PS01208
DomainVWFC_2

CRIM1 SSPOP JAG2 MUC5B CHRD MUC2

2.82e-06381996PS50184
DomainVWC

CRIM1 SSPOP JAG2 MUC5B CHRD MUC2

2.82e-06381996SM00214
DomainC8

SSPOP MUC5B MUC2 OTOG

5.79e-06121994PF08742
DomainTIL

SSPOP MUC5B MUC2 OTOG

5.79e-06121994PF01826
DomainUnchr_dom_Cys-rich

SSPOP MUC5B MUC2 OTOG

8.29e-06131994IPR014853
DomainC8

SSPOP MUC5B MUC2 OTOG

8.29e-06131994SM00832
DomainTIL_dom

SSPOP MUC5B MUC2 OTOG

1.15e-05141994IPR002919
DomainVWF_type-D

SSPOP MUC5B MUC2 OTOG

2.06e-05161994IPR001846
DomainVWFD

SSPOP MUC5B MUC2 OTOG

2.06e-05161994PS51233
DomainVWD

SSPOP MUC5B MUC2 OTOG

2.06e-05161994SM00216
DomainVWD

SSPOP MUC5B MUC2 OTOG

2.06e-05161994PF00094
DomainFN3

SPEG CRLF2 MID1 CNTFR COL7A1 MID2 IFNLR1 TRIM67 TNR EPHA10

5.61e-0519919910PS50853
DomainFN3_dom

SPEG CRLF2 MID1 CNTFR COL7A1 MID2 IFNLR1 TRIM67 TNR EPHA10

8.46e-0520919910IPR003961
DomainCys_knot_C

SSPOP MUC5B MUC2 OTOG

1.33e-04251994IPR006207
DomainCTCK_2

SSPOP MUC5B MUC2 OTOG

1.33e-04251994PS01225
DomainEGF_2

SSPOP JAG2 C9 NOTCH3 HSPG2 LAMA5 LTBP3 TNR AGRN EPHA10 PROS1

1.33e-0426519911PS01186
DomainLDLRA_1

SSPOP PKD1 C9 HSPG2 LRP3

1.54e-04481995PS01209
DomainFN3

SPEG CRLF2 MID1 CNTFR COL7A1 MID2 TRIM67 TNR EPHA10

1.69e-041851999SM00060
DomainLDLRA_2

SSPOP PKD1 C9 HSPG2 LRP3

1.70e-04491995PS50068
DomainLaminin_G_1

HSPG2 AGRN PROS1

1.85e-04111993PF00054
DomainIg-like_fold

SPEG CRLF2 FCRL3 MID1 TREML1 PLXNB1 CNTFR HSPG2 SEMA4B COL7A1 ADAMTSL1 MID2 IFNLR1 TRIM67 PLXNC1 WFIKKN1 FCRL4 TNR EPHA10

2.04e-0470619919IPR013783
DomainEGF_3

SSPOP JAG2 C9 NOTCH3 HSPG2 LTBP3 TNR AGRN PROS1 OTOG

2.21e-0423519910PS50026
DomainCOS

MID1 MID2 TRIM67

2.44e-04121993PS51262
DomainCOS_domain

MID1 MID2 TRIM67

2.44e-04121993IPR017903
Domain-

SPEG CRLF2 FCRL3 MID1 TREML1 PLXNB1 CNTFR HSPG2 COL7A1 ADAMTSL1 MID2 IFNLR1 TRIM67 PLXNC1 WFIKKN1 FCRL4 TNR EPHA10

2.71e-04663199182.60.40.10
DomainGrowth_fac_rcpt_

CRIM1 JAG2 C9 NOTCH3 HSPG2 LAMA5 LTBP3 PROS1

2.73e-041561998IPR009030
DomainTFIID-31

TAF9 TAF9B

3.36e-0431992IPR003162
DomainTFIID-31kDa

TAF9 TAF9B

3.36e-0431992PF02291
DomainEGF-like_dom

JAG2 C9 NOTCH3 HSPG2 LAMA5 LTBP3 TNR AGRN PROS1 OTOG

3.50e-0424919910IPR000742
Domainfn3

SPEG MID1 CNTFR COL7A1 MID2 TRIM67 TNR EPHA10

3.52e-041621998PF00041
DomainEGF_1

SSPOP JAG2 C9 NOTCH3 HSPG2 LAMA5 LTBP3 TNR AGRN PROS1

4.22e-0425519910PS00022
DomainBbox_C

MID1 MID2 TRIM67

4.93e-04151993IPR003649
DomainBBC

MID1 MID2 TRIM67

4.93e-04151993SM00502
DomainEGF-like_CS

JAG2 C9 NOTCH3 HSPG2 LAMA5 LTBP3 TNR AGRN EPHA10 PROS1

5.06e-0426119910IPR013032
DomainTSP_1

SSPOP ADAMTS17 C9 ADAMTSL1 THSD7B

5.56e-04631995PF00090
DomainTSP1

SSPOP ADAMTS17 C9 ADAMTSL1 THSD7B

6.42e-04651995SM00209
DomainTSP1_rpt

SSPOP ADAMTS17 C9 ADAMTSL1 THSD7B

6.42e-04651995IPR000884
DomainTSP1

SSPOP ADAMTS17 C9 ADAMTSL1 THSD7B

6.42e-04651995PS50092
DomainLAM_G_DOMAIN

HSPG2 LAMA5 AGRN PROS1

6.95e-04381994PS50025
DomainLDLR_class-A_CS

SSPOP C9 HSPG2 LRP3

8.46e-04401994IPR023415
DomainCTCK_1

SSPOP MUC5B MUC2

8.64e-04181993PS01185
Domain-

PKN3 PKN1

1.11e-03519921.10.287.160
DomainLamG

HSPG2 LAMA5 AGRN PROS1

1.22e-03441994SM00282
DomainLdl_recept_a

SSPOP C9 HSPG2 LRP3

1.32e-03451994PF00057
DomainPROTEIN_KINASE_ATP

SPEG MAST4 MYLK3 RPS6KL1 PKN3 AMHR2 RET TESK1 TGFBR1 TNK2 PKN1 MARK2 EPHA10

1.33e-0345919913PS00107
Domain-

SSPOP C9 HSPG2 LRP3

1.44e-034619944.10.400.10
DomainCT

MUC5B MUC2 OTOG

1.58e-03221993SM00041
DomainWxxW_domain

MUC5B MUC2

1.65e-0361992IPR025155
DomainMucin2_WxxW

MUC5B MUC2

1.65e-0361992PF13330
DomainLDrepeatLR_classA_rpt

SSPOP C9 HSPG2 LRP3

1.82e-03491994IPR002172
DomainLDLa

SSPOP C9 HSPG2 LRP3

1.82e-03491994SM00192
DomainZnf_RING_CS

CBLC RNF125 MID1 RC3H2 MID2 TRIM67 TRIM62

1.85e-031631997IPR017907
DomainEGF_CA

JAG2 NOTCH3 HSPG2 LTBP3 AGRN PROS1

1.97e-031221996SM00179
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

VWA5B2 HIP1 SPEG CBLC EXOSC8 JADE1 ADCY9 JAG2 DIP2A TNRC18 WIZ PKD1 KCTD15 DENND5A ZNF579 BRAT1 DYNC1H1 PKN3 BAHCC1 NPC1 HSPG2 SEMA4B CRYBG2 KMT5C SOCS3 FBRSL1 LAMA5 GRIN2D TESK1 IFNLR1 CCDC142 HIVEP3 NCOR2 EFNA2 LRP3 TNK2 PKN1 LTBP3 AGRN CEP170B PPP1R16A

5.56e-2111052084135748872
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

MDM4 NBPF19 PRR14 TNRC18 KLF5 SCN10A DYNC1H1 FAM110B ARHGEF5 RET NCOR2 NUP155 TNK2 ZKSCAN4 LRRFIP1 CRTC2

8.44e-094302081635044719
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

KDM5B DLG5 AMER1 MDM4 FAM53C CDCA2 STOX2 MAST4 MYLK3 NHS FAM110B ARHGEF5 APBB1 APC TESK1 SCRIB MARK2 SRRM2 CEP170B CRTC2 OTOG

6.17e-088612082136931259
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

GMIP ITPR1 DIP2A MID1 DENND5A PLXNB1 RC3H2 ARHGEF5 FBRSL1 APC RBM20 NUP155 SCRIB GALNT6 MARK2 AGRN CRTC2

4.54e-076502081738777146
Pubmed

Notch3 and Jagged2 contribute to gastric cancer development and to glandular differentiation associated with MUC2 and MUC5AC expression.

JAG2 NOTCH3 MUC2

8.40e-074208322691042
Pubmed

Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis.

HSPG2 COL7A1 LAMA5 TGFBR1 CDH1

2.05e-0635208518676816
Pubmed

Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.

MID1 MID2 TRIM67

4.16e-066208316434393
Pubmed

Laminin alpha1 globular domains 4-5 induce fetal development but are not vital for embryonic basement membrane assembly.

HSPG2 LAMA5 AGRN

4.16e-066208315668394
Pubmed

Foxp1/4 control epithelial cell fate during lung development and regeneration through regulation of anterior gradient 2.

JAG2 NOTCH3 MUC5B CDH1 MUC2

4.59e-0641208522675208
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

ADAMTS17 HSPG2 COL7A1 ADAMTSL1 LAMA5 COL23A1 MUC2 AGRN

8.03e-06167208822159717
Pubmed

Renal collecting system growth and function depend upon embryonic γ1 laminin expression.

HSPG2 RET CDH1 AGRN

1.01e-0523208421903675
Pubmed

Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.

COL7A1 LAMA5 AGRN

1.15e-058208312766770
Pubmed

p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate.

JAG2 COL7A1 ZNF750 CDH1

1.20e-0524208428604778
Pubmed

Loss of DLG5 promotes breast cancer malignancy by inhibiting the Hippo signaling pathway.

DLG5 SCRIB CDH1

1.72e-059208328169360
Pubmed

Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.

HSPG2 COL7A1 LAMA5 AGRN

2.63e-0529208422613833
Pubmed

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

JAG2 KLF5 UTF1 NOTCH3 SOCS3 TGFBR1

3.18e-05100208624859004
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

JAG2 NOTCH3 CDH1

3.36e-0511208316607638
Pubmed

Loss-of-function mutations in FREM2 disrupt eye morphogenesis.

CBLC COL7A1 CDH1

3.36e-0511208330802441
Pubmed

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

HSPG2 CDH1 AGRN

3.36e-0511208317023412
Pubmed

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

NOTCH3 HSPG2 LAMA5 CDH1

3.45e-0531208422274697
Pubmed

Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.

APC TGFBR1

3.56e-052208219147584
Pubmed

Laminin 5 binds the NC-1 domain of type VII collagen.

COL7A1 LAMA5

3.56e-05220829245798
Pubmed

RET signaling is required for survival and normal function of nonpeptidergic nociceptors.

SCN10A RET

3.56e-052208220237269
Pubmed

Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.

HSPG2 AGRN

3.56e-052208225506919
Pubmed

Scribble and E-cadherin cooperate to control symmetric daughter cell positioning by multiple mechanisms.

SCRIB CDH1

3.56e-052208236661138
Pubmed

Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function.

AMHR2 TGFBR1

3.56e-052208222028666
Pubmed

A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation.

RNF125 NCOR2

3.56e-052208215843525
Pubmed

Proteomic and postproteomic characterization of keratan sulfate-glycanated isoforms of thyroglobulin and transferrin uniquely elaborated by papillary thyroid carcinomas.

TF TG

3.56e-052208212819023
Pubmed

GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation.

GLP1R RET

3.56e-052208222234463
Pubmed

Effect of Recql5 deficiency on the intestinal tumor susceptibility of Apc(min) mice.

RECQL5 APC

3.56e-052208220333788
Pubmed

E-Cadherin Facilitates Protein Kinase D1 Activation and Subcellular Localization.

PKD1 CDH1

3.56e-052208226991955
Pubmed

The mammalian Scribble polarity protein regulates epithelial cell adhesion and migration through E-cadherin.

SCRIB CDH1

3.56e-052208216344308
Pubmed

Loss of the SMRT/NCoR2 corepressor correlates with JAG2 overexpression in multiple myeloma.

JAG2 NCOR2

3.56e-052208219417136
Pubmed

Epigenetic and genetic alterations of APC and CDH1 genes in lobular breast cancer: relationships with abnormal E-cadherin and catenin expression and microsatellite instability.

APC CDH1

3.56e-052208212800196
Pubmed

Epigenetic alterations of CDH1 and APC genes: relationship with activation of Wnt/beta-catenin pathway in invasive ductal carcinoma of breast.

APC CDH1

3.56e-052208218662704
Pubmed

Sprouty-4 negatively regulates cell spreading by inhibiting the kinase activity of testicular protein kinase.

TESK1 SPRY4

3.56e-052208215584898
Pubmed

Winnie-APCMin/+ Mice: A Spontaneous Model of Colitis-Associated Colorectal Cancer Combining Genetics and Inflammation.

APC MUC2

3.56e-052208232340123
Pubmed

Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.

APC MUC2

3.56e-052208218794118
Pubmed

Potential clinical utility of MUC5B und TOLLIP single nucleotide polymorphisms (SNPs) in the management of patients with IPF.

TOLLIP MUC5B

3.56e-052208233639995
Pubmed

Phosphorylation state regulates the localization of Scribble at adherens junctions and its association with E-cadherin-catenin complexes.

SCRIB CDH1

3.56e-052208221146521
Pubmed

Microsatellite analysis of the APC gene and immunoexpression of E-cadherin, catenin, and tubulin in esophageal squamous cell carcinoma.

APC CDH1

3.56e-052208216426911
Pubmed

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.

APC MUC2

3.56e-052208219232344
Pubmed

Craniopharyngiomas express embryonic stem cell markers (SOX2, OCT4, KLF4, and SOX9) as pituitary stem cells but do not coexpress RET/GFRA3 receptors.

GFRA3 RET

3.56e-052208222031517
Pubmed

Tensin4 (TNS4) is upregulated by Wnt signalling in adenomas in multiple intestinal neoplasia (Min) mice.

APC TNS4

3.56e-052208232567731
Pubmed

Crystal structure of the human Scribble PDZ1 domain bound to the PDZ-binding motif of APC.

APC SCRIB

3.56e-052208230659601
Pubmed

Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.

PKD1 TGFBR1

3.56e-052208227020852
Pubmed

AMER1 regulates the distribution of the tumor suppressor APC between microtubules and the plasma membrane.

AMER1 APC

3.56e-052208217925383
Pubmed

CDCA2 promotes proliferation and migration of melanoma by upregulating CCAD1.

CDCA2 CDH1

3.56e-052208232633378
Pubmed

Telomere length and genetic variant associations with interstitial lung disease progression and survival.

TOLLIP MUC5B

3.56e-052208230635297
Pubmed

E-cadherin and adenomatous polyposis coli mutations are synergistic in intestinal tumor initiation in mice.

APC CDH1

3.56e-052208211040191
Pubmed

Human sprouty 4, a new ras antagonist on 5q31, interacts with the dual specificity kinase TESK1.

TESK1 SPRY4

3.56e-052208212027893
Pubmed

CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells.

SEMA4B DCBLD2

3.56e-052208217213806
Pubmed

In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.

TAF9 TAF9B

3.56e-052208212837753
Pubmed

Loss of E-cadherin and MUC2 expressions correlated with poor survival in patients with stages II and III colorectal carcinoma.

CDH1 MUC2

3.56e-052208220865330
Pubmed

Whole-Exome Sequencing in Familial Parkinson Disease.

TNK2 TNR

3.56e-052208226595808
Pubmed

Expression of N-Acetylgalactosaminyltransferase-6 Is Related to Expression of Cell Adhesion Molecules in Endometrial Cancer.

GALNT6 CDH1

3.56e-052208228668893
Pubmed

Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice.

AMHR2 APC

3.56e-052208221664244
Pubmed

Dietary induction of colonic tumors in a mouse model of sporadic colon cancer.

APC MUC2

3.56e-052208218829535
Pubmed

Mid1/Mid2 expression in craniofacial development and a literature review of X-linked opitz syndrome.

MID1 MID2

3.56e-052208226788540
Pubmed

Distribution of GDNF family receptor alpha3 and RET in rat and human non-neural tissues.

GFRA3 RET

3.56e-052208216773224
Pubmed

Expressions of two adenomatous polyposis coli and E-cadherin proteins on human colorectal cancers.

APC CDH1

3.56e-052208212647217
Pubmed

TOLLIP, MUC5B, and the Response to N-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis.

TOLLIP MUC5B

3.56e-052208226331942
Pubmed

Type VII collagen is required for Ras-driven human epidermal tumorigenesis.

COL7A1 LAMA5

3.56e-052208215774758
Pubmed

[Interleukin-1beta induces MUC2/MUC5B gene expression in human nasal epithelial cells].

MUC5B MUC2

3.56e-052208220873538
Pubmed

Sprouty4 mediates amphiregulin-induced down-regulation of E-cadherin and cell invasion in human ovarian cancer cells.

SPRY4 CDH1

3.56e-052208226768617
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

FAM234A CRIM1 FKBP9 ITPR1 JAG2 PLXNB1 NOTCH3 NPC1 HSPG2 SEMA4B COL7A1 LAMA5 TGFBR1 MICAL2 LTBP3 SCRIB AGRN DCBLD2 LRRFIP1 PROS1

3.93e-0512012082035696571
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DLG5 MAST4 NHS RC3H2 APC ZDBF2 SCRIB CEP170B

4.04e-05209208836779422
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

NAPEPLD ENPP3 EVPL WIZ PKD1 SCN10A TOLLIP HRG C9 DYNC1H1 NPC1 DNHD1 HSPG2 MID2 LAMA5 TF GAA CRTC2

4.42e-0510162081819056867
Pubmed

Synergistic activities of alpha3 and alpha6 integrins are required during apical ectodermal ridge formation and organogenesis in the mouse.

HSPG2 LAMA5 CDH1

4.46e-0512208310433923
Pubmed

Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.

HSPG2 LAMA5 AGRN

4.46e-0512208316750824
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

HIP1 CBLC WDR18 JADE1 CDCA2 PRR14 KARS1 WIZ DENND5A ZNF579 NOTCH3 PMAIP1 CNTFR ZC3H12A SOCS3 APBB1 DGKD WFIKKN1 PKN1

5.06e-0511242081921900206
Pubmed

Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling.

RET CDH1 NEUROG3

5.77e-0513208328341395
Pubmed

Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.

HSPG2 LAMA5 AGRN

5.77e-0513208312682087
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

FAM234A NPC1 HSPG2 LAMA5 MUC5B GALNT6 AGRN

6.23e-05164208732409323
Pubmed

Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice.

GLP1R CDH1 NEUROG3

7.31e-0514208326518685
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ANKS1B WDR18 STOX2 WIZ DYNC1H1 APC TRIOBP GRIN2D NCOR2 TRIM67 PKN1 SCRIB GOLGA8A TNR AGRN CEP170B LRRFIP1

7.56e-059632081728671696
Pubmed

PlexinA1 signaling directs the segregation of proprioceptive sensory axons in the developing spinal cord.

PLXNB1 SEMA4B SLITRK3 EFNA2 PLXNC1 DCBLD2

7.67e-05117208617145500
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

SSPOP ADAMTS17 ADAMTSL1 THSD7B CDH1

8.96e-0575208520637190
Pubmed

Prickle1 mutation causes planar cell polarity and directional cell migration defects associated with cardiac outflow tract anomalies and other structural birth defects.

APC SCRIB CDH1

9.10e-0515208326883626
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

AMER1 MDM4 SSPOP JAG2 TNRC18 DENND5A RPS6KL1 NOTCH3 MID2 FBRSL1 TRIOBP SLITRK3 SKI COL23A1 HIVEP3 NCOR2 MICAL2 TNK2 PKN1 VGLL4 PRDM15 CEP170B

9.35e-0514892082228611215
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

SSPOP HRG HSPG2 COL7A1 ADAMTSL1 LAMA5 AGRN

9.36e-05175208728071719
Pubmed

Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.

KLF5 APC

1.06e-043208220298593
Pubmed

CD2AP and Cbl-3/Cbl-c constitute a critical checkpoint in the regulation of ret signal transduction.

CBLC RET

1.06e-043208218753381
Pubmed

Mutational analysis of E-cadherin, β-catenin and APC genes in synovial sarcomas.

APC CDH1

1.06e-043208220840677
Pubmed

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli.

APC SCRIB

1.06e-043208216611247
Pubmed

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase.

TGFBR1 CDH1

1.06e-043208225421310
Pubmed

CD2-associated protein (CD2AP) enhances casitas B lineage lymphoma-3/c (Cbl-3/c)-mediated Ret isoform-specific ubiquitination and degradation via its amino-terminal Src homology 3 domains.

CBLC RET

1.06e-043208224425877
Pubmed

Identification of a putative target for Rho as the serine-threonine kinase protein kinase N.

PKN3 PKN1

1.06e-04320828571127
Pubmed

Dlg5 interacts with the TGF-β receptor and promotes its degradation.

DLG5 TGFBR1

1.06e-043208223624079
Pubmed

TGFBR1 is required for mouse myometrial development.

AMHR2 TGFBR1

1.06e-043208224506537
Pubmed

Expression of APC, β-catenin and E-cadherin in Tunisian patients with gastric adenocarcinoma: clinical significance.

APC CDH1

1.06e-043208224197976
Pubmed

Genes causing clefting syndromes as candidates for non-syndromic cleft lip with or without cleft palate: a family-based association study.

JAG2 MID1

1.06e-043208219049519
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC2

1.06e-043208219718741
Pubmed

Protein Expression Analysis in Uterine Cervical Cancer for Potential Targets in Treatment.

NOTCH3 SOCS3

1.06e-043208229532409
Pubmed

Haploinsufficiency of Krüppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine.

KLF5 APC

1.06e-043208219435907
Pubmed

Autocrine regulation of early embryonic development by the artemin-GFRA3 (GDNF family receptor-alpha 3) signaling system in mice.

GFRA3 RET

1.06e-043208219580811
Pubmed

Deletion of TNF in Winnie-APCMin/+ Mice Reveals Its Dual Role in the Onset and Progression of Colitis-Associated Colorectal Cancer.

APC MUC2

1.06e-043208236499472
Pubmed

MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.

MID1 MID2

1.06e-043208211806752
Pubmed

IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis.

IL17C IL17RC

1.06e-043208220231694
Pubmed

Genetic changes of CDH1, APC, and CTNNB1 found in human brain tumors.

APC CDH1

1.06e-043208217905526
InteractionTOP3B interactions

VWA5B2 HIP1 SPEG CBLC EXOSC8 JADE1 ADCY9 JAG2 DIP2A TNRC18 KARS1 WIZ RECQL5 PKD1 KCTD15 DENND5A ZNF579 BRAT1 DYNC1H1 PKN3 BAHCC1 NPC1 HSPG2 SEMA4B RC3H2 CRYBG2 MID2 KMT5C SOCS3 FBRSL1 LAMA5 GRIN2D TESK1 IFNLR1 CCDC142 HIVEP3 NCOR2 EFNA2 LRP3 TNK2 PKN1 LTBP3 AGRN CEP170B PPP1R16A

1.24e-11147020345int:TOP3B
GeneFamilyFibronectin type III domain containing

CRLF2 MID1 CNTFR COL7A1 MID2 TRIM67 TNR EPHA10

2.06e-051601308555
GeneFamilyBlood group antigens|CD molecules|Proteoglycans

HSPG2 AGRN

1.05e-0371302570
GeneFamilyPlexins

PLXNB1 PLXNC1

1.79e-0391302683
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKD DGKK

2.22e-031013021178
GeneFamilyC2 domain containing protein kinases

PKN3 PKN1

2.22e-03101302835
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

SPEG ITPR1 JAG2 PKD1 RPS6KL1 LAMA5 TNK2 GOLGA8A CELF2-AS1

7.58e-061662089M39026
CoexpressionNABA_CORE_MATRISOME

VWA5B2 CRIM1 SSPOP HSPG2 COL7A1 LAMA5 COL23A1 LTBP3 TNR AGRN OTOG

1.14e-0527020811MM17057
CoexpressionNABA_CORE_MATRISOME

VWA5B2 CRIM1 SSPOP HSPG2 COL7A1 LAMA5 COL23A1 LTBP3 TNR AGRN OTOG

1.35e-0527520811M5884
CoexpressionNABA_MATRISOME

VWA5B2 CRIM1 IL17C SSPOP ADAMTS17 HRG PLXNB1 HSPG2 SEMA4B COL7A1 ADAMTSL1 LAMA5 MUC5B COL23A1 PLXNC1 WFIKKN1 CHRD LTBP3 TNR MUC2 AGRN OTOG

1.87e-05100820822MM17056
CoexpressionNABA_MATRISOME

VWA5B2 CRIM1 IL17C SSPOP ADAMTS17 HRG PLXNB1 HSPG2 SEMA4B COL7A1 ADAMTSL1 LAMA5 MUC5B COL23A1 PLXNC1 WFIKKN1 CHRD LTBP3 TNR MUC2 AGRN OTOG

2.44e-05102620822M5889
CoexpressionGSE3982_BASOPHIL_VS_EFF_MEMORY_CD4_TCELL_DN

ANKS1B WDR18 WIZ GRIN2D RET TF PLXNC1 MICAL2 GAA

2.85e-051962089M5557
CoexpressionGSE36392_TYPE_2_MYELOID_VS_MAC_IL25_TREATED_LUNG_UP

KDM5B KLF5 CREB3L3 PLXNB1 CASS4 ADAMTSL1 SOCS3 SAPCD2 GALNT6

3.34e-052002089M5273
CoexpressionOSADA_ASCL1_TARGETS_DN

CRIM1 KLF5 SOCS3 CDH1

3.61e-05242084M4336
ToppCellChildren_(3_yrs)-Epithelial-basal_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRMPD4 MID1 NHS PLXNB1 ATP13A4 COL7A1 LAMA5 TNS4 GOLGA8A

5.68e-0815720896ee2692f705bdd93ba523dffaf2f0cd921b47e28
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FRMPD4 CBLC KLF5 COL7A1 FOXO6 TBC1D3L GAL3ST1 TNS4 PRODH

6.00e-08158208998712ed7e8e65e8c5ff9318cf0e0a04e271a055d
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

CBLC JAG2 MAST4 KLF5 NHS ATP13A4 COL7A1 TNS4 CDH1

2.10e-0718320890f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS1B CBLC PLXNB1 COL7A1 GAL3ST1 SLITRK3 COL23A1 PLXNC1 CDH1

2.31e-07185208911c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

CBLC STOX2 MAST4 KLF5 NHS PLXNB1 ATP13A4 COL7A1 TNS4

2.53e-0718720898407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

JADE1 KLF5 HSPG2 ATP13A4 ADAMTSL1 LAMA5 GOLGA8A CDH1 AGRN

2.64e-071882089eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

CBLC MAST4 KLF5 MID1 NHS COL7A1 LAMA5 TNS4 CDH1

3.16e-0719220899b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellwk_15-18-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EVPL KLF5 HSPG2 ADAMTSL1 LAMA5 GOLGA8A CDH1 AGRN PRODH

3.60e-0719520890e3aac1b1a1fd483f5fb9a394eb90c0e1ce63542
ToppCellmedial-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EVPL KLF5 HSPG2 ATP13A4 CRYBG2 MICAL2 GOLGA8A CDH1 AGRN

4.27e-071992089456460c761e26ed4b1d88d9bee4d2a7c9bd9d416
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EVPL KLF5 HSPG2 ATP13A4 CRYBG2 MICAL2 GOLGA8A CDH1 AGRN

4.27e-071992089c11365653c69a5dfb37946231f8af05149a61a71
ToppCellmedial-Epithelial-Alveolar_Epithelial_Type_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

EVPL KLF5 HSPG2 ATP13A4 CRYBG2 MICAL2 GOLGA8A CDH1 AGRN

4.27e-0719920895263338242f95c04690d0795749ccc20b0d19f7a
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 KLF5 NHS ZDBF2 GRIN2D RBM20 PLXNC1 DGKK

1.18e-061662088548d0d6c0ffd564036ddba78620734220ebb73d7
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWA5B2 KLF5 NHS ZDBF2 GRIN2D RBM20 PLXNC1 DGKK

1.18e-06166208880e164a89d22098cabe4a99a78283ba69ea0561e
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL JAG2 KCTD15 BRAT1 BAHCC1 IPPK SHISA2 TXLNB

1.41e-061702088d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ANKS1B FAM161A CCDC157 SHISA2 ZDBF2 IL17RC MICAL2 CEP170B

1.54e-061722088d65ffff3e341af34a043a0d802d7ba4b69de36e9
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5B KLF5 NOTCH3 PMAIP1 CRYBG2 ZC3H12A IL17RC ZNF750

1.60e-0617320880f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCellChildren_(3_yrs)-Epithelial-basal_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

FRMPD4 NHS PLXNB1 ATP13A4 COL7A1 LAMA5 TNS4 GOLGA8A

1.98e-061782088fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCellBasal|World / shred by cell class for mouse tongue

HIP1 CRIM1 FKBP9 JAG2 COL7A1 LAMA5 TNS4 AGRN

2.44e-061832088c6729a207526ff4aa48176207b9353176f631fea
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CRIM1 ANKS1B ITPR1 MID1 NHS NOTCH3 MICAL2 LRRFIP1

2.98e-06188208834e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENPP3 CRLF2 GFRA3 AMHR2 RET TRIM67 GALNT6 DCBLD2

3.10e-061892088aba941ba6ce7702418b3f470bde573d123c4aade
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

HIP1 CRIM1 ANKS1B ITPR1 MID1 NHS NOTCH3 MICAL2

3.10e-0618920886b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

CBLC MAST4 KLF5 NHS COL7A1 LAMA5 TNS4 CDH1

3.22e-061902088ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENPP3 DBNDD2 CBLC RNF125 NOTCH3 CRYBG2 ZNF750 TNK2

3.22e-0619020880bad41d19dc515e6bc61e699f4d56664cf2e72fd
ToppCellBasal_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

JAG2 NHS PLXNB1 COL7A1 CAPS LAMA5 TNS4 GOLGA8A

3.35e-061912088a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENPP3 CRLF2 GFRA3 AMHR2 RET TRIM67 GALNT6 DCBLD2

3.48e-061922088690cf19e9b0b2ada80097c63eae827529aa5b6f3
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENPP3 CRLF2 GFRA3 AMHR2 RET TRIM67 GALNT6 DCBLD2

3.48e-0619220883d6c4c5847ca1e44fa380403d25af45d5b51ee9b
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENPP3 CRLF2 GFRA3 AMHR2 RET TRIM67 GALNT6 DCBLD2

3.48e-061922088e0412964a3ee1bf3c0ef64f9a6f20f7e7835701e
ToppCell5'-Airway_Nasal-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENPP3 CRLF2 GFRA3 AMHR2 RET TRIM67 GALNT6 DCBLD2

3.48e-061922088b5871247a5f3e970fa05b33fff21bef9d2ab5741
ToppCellfacs-Trachea-24m-Epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CBLC KLF5 PLXNB1 CRYBG2 LAMA5 MUC5B TG CDH1

3.62e-061932088ec49a83b24371579d4ad46aad91c25115aa226f9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADCY9 MAST4 NPC1 DGKD MICAL2 SPRY4 FHDC1 CDH1

3.76e-06194208897534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCellMild/Remission-B_naive-8|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HIP1 CRIM1 MDM4 FOXO6 DGKD HIVEP3 ELF2 LRRFIP1

3.90e-0619520880a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JAG2 KLF5 PMAIP1 SEMA4B COL7A1 ZC3H12A ARHGEF5 TNS4

4.37e-061982088fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Airway-Club|Control_saline / Treatment groups by lineage, cell group, cell type

GFRA3 CRYBG2 SYT6 MUC5B TF IFNLR1 NOTO GALNT6

4.53e-0619920885cc8b553a58669a30eb10845beb23983dcdf5a6a
ToppCellnormal_Pleural_Fluid-Epithelial_cells|normal_Pleural_Fluid / Location, Cell class and cell subclass

FKBP9 CBLC KLF5 HSPG2 LAMA5 CDH1 AGRN DCBLD2

4.53e-061992088564ba7acd03be2d6e4d0850cb2c7237a788dc275
ToppCellAdult-Epithelial-basal_cell-D175|Adult / Lineage, Cell type, age group and donor

CBLC NHS RPS6KL1 COL7A1 BRME1 TNS4 RTN4RL2

7.81e-0615320879ee3e7f3f19a2474283c1c79045269686f35a541
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_1-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Tuba1c))|Striatum / BrainAtlas - Mouse McCarroll V32

ENPP3 CDCA2 CREB3L3 TROAP SAPCD2 KIF18B

7.99e-0610120860b32e6071f05dbe808e51e18c3a3f8221f438f83
ToppCellLPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NHS CNTFR DNHD1 SEMA4B FBRSL1 HIVEP3 WFIKKN1

9.64e-0615820877f5426585d0d299d2b48e5fcb349950feffdef33
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDM4 KMT5C SLITRK3 TRIM67 ZNF518B FHDC1 CEP170B

1.18e-051632087953a7db7e90a913e81002d2141fbbd5f1fdf2197
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KDM5B EVPL MYLK3 KLF5 NOTCH3 CRYBG2 ZNF750

1.38e-05167208702c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

WDR18 FBXL18 ZNF579 SOWAHD TGFBR1 LRP3 PRDM15

1.38e-051672087a48349f189f6a8d563744b0a294c3974f3a18f50
ToppCellfacs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 GLP1R ADAMTS17 PKN3 SHISA2 IFNLR1 COL23A1

1.44e-05168208706dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCellfacs-Heart-RA-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CRIM1 GLP1R ADAMTS17 PKN3 SHISA2 IFNLR1 COL23A1

1.44e-0516820871002f058a340763e3d8de0bd1f0547a903526ec6
ToppCellfacs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSC1A1 ITPR1 HRG NPC1 HIVEP3 SLC9A1 CDH1

1.61e-0517120876a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCellfacs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RSC1A1 ITPR1 HRG NPC1 HIVEP3 SLC9A1 CDH1

1.61e-051712087e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCellCerebellum-Macroglia-OLIGODENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

ENPP3 PRR18 CRYBG2 GAL3ST1 GALNT6 NEUROG3

1.68e-05115208615b2c11225802cc15c01165d84a755432f02d82f
ToppCellMild/Remission-B_naive-8|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

HIP1 CRIM1 MDM4 FOXO6 DGKD ELF2 LRRFIP1

1.74e-051732087694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

FRMPD4 JAG2 NHS PROB1 COL7A1 TNS4 GOLGA8A

1.80e-051742087a4f98afe7d1cc2617f6f7bc8092c41df57474b30
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FTSJ1 STOX2 PKN3 IPPK HSPG2 NCOR2 PLXNC1

1.87e-05175208798dc3b6f69a29d587f503898f09912700950e3d9
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 RAD54L TROAP GAL3ST1 BRME1 KIF18B CDH1

1.87e-051752087fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

CDCA2 RAD54L TROAP GAL3ST1 BRME1 KIF18B CDH1

1.87e-05175208736c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCelldroplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDCA2 UTF1 TROAP BRME1 SAPCD2 TNS4 KIF18B

1.94e-051762087581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCellAT1_cells-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

HSPG2 CRYBG2 SOCS3 LAMA5 GOLGA8A CDH1 EPHA10

1.94e-0517620874a30bb771297b30926fb98e2b5ec0dbdc46feac7
ToppCellASK428-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

COL7A1 SH2D3C TG TAF9B TNS4 GOLGA8A SP140

2.01e-05177208766074a288501c136b4e83b883db5f0d8269ee326
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRMPD4 CBLC JAG2 MID1 NHS COL7A1 TNS4

2.01e-051772087cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRMPD4 CBLC JAG2 MID1 NHS COL7A1 TNS4

2.01e-051772087ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellCOPD-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

FRMPD4 CBLC JAG2 FAM157A COL7A1 TNS4 GOLGA8A

2.09e-051782087441d1dba720141891b11f404744c59834d80e6c5
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-Double_negative_Thymocyte,_DN4_(Cd8-,_Cd4-),_some_undergoing_VDJ_recombination_|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DLG5 ADCY9 UTF1 AMHR2 RET TNK2 TNS4

2.09e-051782087408e41c853f608965cef9111fb87fdc311cdc7a8
ToppCellCD8+_Memory_T_cell-FLU-5|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

NCF1 ANKS1B SOCS3 TG GOLGA8A CDH1 CEP170B

2.16e-0517920877f18dffa85285599662edbcd3f32ab42672bffb8
ToppCellEpithelial-basal_cell|World / Lineage, Cell type, age group and donor

KLF5 NHS ATP13A4 COL7A1 LAMA5 TNS4 GOLGA8A

2.16e-051792087d9be6647ec7b22747dc00dce4ea307b6af412dfa
ToppCellfacs-Skin-Anagen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL KLF5 NOTCH3 CRYBG2 IL17RC ZNF750 PRODH

2.16e-0517920874a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCellfacs-Marrow-B-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR1 NPC1 SEMA4B APC HIVEP3 TGFBR1 CDH1

2.24e-051802087bf8d13d4db1af55b8c9fe16aaccf8743e000e005
ToppCellfacs-Marrow-B-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR1 NPC1 SEMA4B APC HIVEP3 TGFBR1 CDH1

2.24e-05180208782965ed1b72a1873c24dd4553d39681596057316
ToppCell10x5'-lymph-node_spleen-Myeloid_Mac-Cycling_Myeloid-Mac|lymph-node_spleen / Manually curated celltypes from each tissue

CDCA2 NOTCH3 RAD54L TROAP COL23A1 LRP3 KIF18B

2.24e-0518020874eea8366cdb82c356325ce88f09ad8b302c17a07
ToppCell3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZBED10P KLF5 PLXNB1 COL7A1 TROAP MUC5B SAPCD2

2.24e-051802087271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCellfacs-Marrow-B-cells-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR1 NPC1 SEMA4B APC HIVEP3 TGFBR1 CDH1

2.24e-051802087839defb40f7cfb2711e9025194de636533f51bcd
ToppCellChildren_(3_yrs)-Immune-enucleated_erythrocyte-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

FTSJ1 JAG2 FAM161A COL7A1 IL17RC TESK1 GOLGA8A

2.41e-0518220873fddadb2ff75013ec6eeb415872667a6bae1da2d
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

JAG2 KLF5 MID1 NHS COL7A1 TNS4 CDH1

2.41e-051822087caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellThalamus-Macroglia-OLIGODENDROCYTE-O2-Trf|Thalamus / BrainAtlas - Mouse McCarroll V32

ENPP3 DBNDD2 PRR18 DENND5A TSPAN32 GALNT6

2.46e-0512320863b97ff4de1e16652291db1c9e2a8474675fcdbfe
ToppCellThalamus-Macroglia-OLIGODENDROCYTE-O2|Thalamus / BrainAtlas - Mouse McCarroll V32

ENPP3 DBNDD2 PRR18 DENND5A TSPAN32 GALNT6

2.46e-051232086fd981879529ced0e3023a1f3f8794ce8ff4d99a8
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

HIP1 CRIM1 SPEG ANKS1B ITPR1 NHS NOTCH3

2.49e-051832087818fd886e0188091310825f9145fa53328f2c979
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD164 KLF5 CRYBG2 IL17RC COL23A1 CDH1 PROS1

2.49e-05183208726b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCellCOPD-Epithelial-ATII|World / Disease state, Lineage and Cell class

MAST4 KLF5 ATP13A4 SHISA2 SPRY4 FHDC1 CDH1

2.49e-0518320878e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

EVPL STOX2 KLF5 ATP13A4 LAMA5 MICAL2 CDH1

2.49e-0518320877b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellfacs-Skin-Telogen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL KLF5 TOLLIP NOTCH3 CRYBG2 IL17RC ZNF750

2.49e-051832087ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 SSPOP ATP13A4 MUC5B DGKK EPHA10 OTOG

2.58e-0518420872cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL KLF5 NOTCH3 PMAIP1 CRYBG2 ZC3H12A ZNF750

2.58e-051842087dc7f6ee4062856a02423fff8b1cce62d46a9355c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 SSPOP ATP13A4 MUC5B DGKK EPHA10 OTOG

2.58e-0518420872b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRMPD4 SSPOP ATP13A4 MUC5B DGKK EPHA10 OTOG

2.58e-051842087ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellControl-Epithelial-Goblet|World / Disease state, Lineage and Cell class

CBLC MAST4 KLF5 NHS ATP13A4 MUC5B CDH1

2.67e-0518520879a793e6016295a63820e9d7563f195494ac692e7
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DLG5 KLF5 NOTCH3 SEMA4B COL7A1 TNS4 CDH1

2.67e-051852087e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADCY9 TNRC18 FAM161A NPC1 CCDC142 TGFBR1 SP140

2.67e-051852087daea170d827226dda6750bf1838ffd82f070c4d4
ToppCell10x5'-Lung-Mast|Lung / Manually curated celltypes from each tissue

ENPP3 EVPL CRLF2 GFRA3 MAST4 HSPG2 AMHR2

2.86e-051872087f8ac5ca5cbe9c6f3d8c0fffc20fe08ca1aea43c0
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KLF5 PLXNB1 COL7A1 GAL3ST1 LAMA5 FHDC1 CDH1

2.86e-051872087fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STOX2 HSPG2 ATP13A4 ADAMTSL1 LAMA5 GOLGA8A AGRN

2.86e-0518720874ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell10x5'-Lung-Mast-Mast_cells|Lung / Manually curated celltypes from each tissue

ENPP3 EVPL CRLF2 GFRA3 MAST4 HSPG2 AMHR2

2.86e-051872087da275d2c774b3e6a8ed77f777dd0676ecf2ddd2c
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ITPR1 NHS FAM110B LAMA5 DGKD VGLL4 TNS4

2.86e-0518720877e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

MAST4 NPC1 DGKD SHISA2 SLC9A1 SPRY4 FHDC1

2.86e-051872087030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-B_cell|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RPS6KL1 SEMA4B MID2 LAMA5 SHROOM1 TXLNB TNR

2.96e-0518820875a0519b189e96001d95f9d24363448e8602b8d4d
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-B_cell-B_cell-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RPS6KL1 SEMA4B MID2 LAMA5 SHROOM1 TXLNB TNR

2.96e-051882087e8b7c1c2eb2e390ad79b358236468b0f15ea58a5
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-B_cell-B_cell|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

RPS6KL1 SEMA4B MID2 LAMA5 SHROOM1 TXLNB TNR

2.96e-05188208799fdd305f75ed38dd507e7a17ffe27c26b86e454
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

MAST4 KLF5 ATP13A4 SHISA2 SPRY4 FHDC1 CDH1

2.96e-051882087eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

MAST4 KLF5 ATP13A4 SHISA2 MICAL2 FHDC1 CDH1

3.17e-051902087d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCellIPF-Epithelial-Goblet|IPF / Disease state, Lineage and Cell class

CBLC MAST4 KLF5 NHS ATP13A4 MUC5B CDH1

3.17e-051902087e41dd5a997ad9952810ffecb57737c03ea1d88b3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 NHS DGKD SHISA2 GRIN2D TRIM67 CHRD

3.17e-051902087e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HIP1 GAL3ST1 SAPCD2 SPRY4 TNK2 RTN4RL2 TNR

3.17e-0519020876c7e1086c0a274cd5527c3104106e372811c9905
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS17 NHS DGKD GRIN2D RBM20 TRIM67 CHRD

3.17e-0519020870acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCellfacs-Lung-EPCAM-3m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CBLC KLF5 PLXNB1 GAL3ST1 RET FHDC1 CDH1

3.28e-051912087629007189034ee8451411428f1c6cc57daee2d91
ToppCellCOVID-19-lung-AT2|lung / Disease (COVID-19 only), tissue and cell type

STOX2 MAST4 ATP13A4 MICAL2 FHDC1 CDH1 DCBLD2

3.28e-051912087276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

STOX2 MAST4 ATP13A4 ADAMTSL1 LAMA5 GOLGA8A CDH1

3.28e-051912087d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellControl-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

STOX2 MAST4 ATP13A4 SHISA2 MICAL2 FHDC1 CDH1

3.39e-0519220871bfd022d5b87cf8a5d5069f559339a553a52a0a2
DrugCephalothin sodium salt [58-71-9]; Up 200; 9.6uM; PC3; HT_HG-U133A

ADCY9 MAST4 RNF125 RECQL5 CRYBG2 SOCS3 APC MUC5B NCOR2 MICAL2 TNS4

1.74e-06196205114482_UP
DiseaseOpitz GBBB syndrome (implicated_via_orthology)

MID1 MID2 TRIM67

5.78e-0661973DOID:0080697 (implicated_via_orthology)
Diseaseresponse to escitalopram, response to citalopram, high density lipoprotein cholesterol measurement

COL23A1 SPRY4

1.32e-0431972EFO_0004612, EFO_0006329, EFO_0007871
DiseaseAutoimmune thyroiditis

FCRL3 TG

2.64e-0441972C0920350
DiseaseFc receptor-like protein 4 measurement

FCRL3 FCRL4

2.64e-0441972EFO_0801599
DiseaseFc receptor-like protein 3 measurement

FCRL3 FCRL4

2.64e-0441972EFO_0008127
DiseaseRectal Neoplasms

APC MUC2

9.11e-0471972C0034885
DiseaseRectal Carcinoma

APC MUC2

9.11e-0471972C0007113
DiseaseMental Retardation, X-Linked 1

FRMPD4 FTSJ1 MID2

1.26e-03321973C2931498
DiseaseAnti-Toxoplasma gondii IgG measurement

NOTCH3 DCBLD2

1.55e-0391972EFO_0009353
DiseaseMitral valve prolapse

KDM5B RBM20 LTBP3

1.78e-03361973HP_0001634
DiseaseGlioblastoma

MDM4 JAG2 NOTCH3 APC

1.96e-03791974C0017636
Diseasebody weight

CRIM1 ANKS1B CBLC ADCY9 ITPR1 MAST4 PKD1 ADAMTS17 KCTD15 NPC1 IPPK IL17RC THSD7B RET DGKK LTBP3 VGLL4 SCRIB

2.07e-03126119718EFO_0004338
Diseasereceptor-interacting serine/threonine-protein kinase 2 measurement

HRG IPPK

2.34e-03111972EFO_0802997
DiseaseGiant Cell Glioblastoma

MDM4 JAG2 NOTCH3 APC

2.45e-03841974C0334588
Diseasepulse pressure measurement

HIP1 CRIM1 SSPOP SNX19 FCSK DIP2A PKD1 SCN10A CCDC157 NOTCH3 NPC1 RC3H2 FBRSL1 TRIOBP LAMA5 COL23A1 HIVEP3 PLXNC1 LTBP3

2.57e-03139219719EFO_0005763
DiseaseIntestinal Neoplasms

APC MUC2

2.80e-03121972C0021841
Diseasemicrophthalmia (implicated_via_orthology)

CRIM1 MID1

2.80e-03121972DOID:10629 (implicated_via_orthology)
DiseaseIntestinal Cancer

APC MUC2

2.80e-03121972C0346627
DiseaseGastric Adenocarcinoma

SPEG TNK2 EPHA10

3.38e-03451973C0278701
DiseaseRS-6-hydroxywarfarin measurement

ANKS1B IPPK ATP13A4 NCOR2 LRP3

3.93e-031551975EFO_0803328
Diseasecannabis dependence measurement

DIP2A RET COL23A1

4.06e-03481973EFO_0008457
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

PLXNB1 GRIN2D NCOR2

4.31e-03491973DOID:0060037 (implicated_via_orthology)
Diseaseglycerate measurement

THSD7B AGRN

4.40e-03151972EFO_0021029
DiseaseN-acetylmethionine measurement

ITPR1 MICAL2

4.40e-03151972EFO_0021427
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

PKD1 SKI TGFBR1

5.37e-03531973C4707243
DiseaseBenign neoplasm of stomach

APC CDH1

5.65e-03171972C0153943
DiseaseNeoplasm of uncertain or unknown behavior of stomach

APC CDH1

5.65e-03171972C0496905
DiseaseCarcinoma in situ of stomach

APC CDH1

5.65e-03171972C0154060
Diseasea disintegrin and metalloproteinase with thrombospondin motifs 13 measurement

HRG PRDM15

5.65e-03171972EFO_0008011
DiseaseIGFBP-3 measurement

FCSK PKN3 FHDC1

5.66e-03541973EFO_0004626
DiseaseMalignant neoplasm of breast

MDM4 JAG2 FCRL3 HRG NHS TREML1 PLXNB1 NOTCH3 RAD54L COL7A1 GRIN2D TESK1 CDH1 LRRFIP1 PRODH

5.85e-03107419715C0006142
Diseasepolyp of colon

MDM4 LAMA5 CDH1

6.27e-03561973MONDO_0021400
DiseaseGlioblastoma Multiforme

MDM4 JAG2 NOTCH3 APC

6.62e-031111974C1621958

Protein segments in the cluster

PeptideGeneStartEntry
RDQVPACLPAACVRP

nan

106

Q6ZRM9
RPSRNTRSCSQPIPE

BHLHB9

266

Q6PI77
VSFVIPCPDRPASQR

FAM234A

66

Q9H0X4
ESETCPPAEPSENRR

FBRSL1

121

Q9HCM7
LSSERFRCPEPIFQP

ACTL10

116

Q5JWF8
SPRVACLLERDPIPA

BRAT1

241

Q6PJG6
PCPRCPRERQASLAS

HTR6

336

P50406
GSRETPRCPAQPSVA

BAHCC1

1631

Q9P281
PRCPAQPSVAASQEA

BAHCC1

1636

Q9P281
LTEVAADRPCPPFLR

CASS4

71

Q9NQ75
RTLGQTQASCPEPRP

CAPS

71

Q13938
QCVDPRLSVSPPSLR

CBLC

31

Q9ULV8
PADPVDLSPRCNLTV

CREB3L3

166

Q68CJ9
ENLPSPRFCDIPSQS

ATG14

436

Q6ZNE5
APERVASFCQPETVP

ATP13A4

626

Q4VNC1
RPPVAFPRRETSCAA

ARHGEF5

536

Q12774
SCETQLPPERSDTPL

FCRL4

211

Q96PJ5
QGALPDPSRSCRVNP

AGRN

321

O00468
ARPRDVLLPVDEPSC

AMER1

1046

Q5JTC6
LRRIFCQPADPAPVA

CCDC142

411

Q17RM4
SCLPAPPAESVARRV

APBB1

671

O00213
ISVRRQFGESPIPPC

DNHD1

876

Q96M86
QCLRESSPAARPSPE

CEP170B

506

Q9Y4F5
PQTCQEPESIPVRAS

CCDC157

181

Q569K6
SDCPQASRPEPQVRR

ADAMTS17

841

Q8TE56
ACSLLDETPPQSPTR

TNK2

596

Q07912
LPTAVEAPPNRRTCV

AMHR2

11

Q16671
VTVTRPRAENPCCPE

MUC5B

5466

Q9HC84
PCVPRFVRSNNVPES

RC3H2

631

Q9HBD1
ALREADFQACPPAAP

RTN4RL2

301

Q86UN3
PEQPDRVACSVPGAR

RBM20

16

Q5T481
PGPSNRPRALEVEEC

HSPG2

1516

P98160
NSRQIRPPPDGSDCT

RAD54L

686

Q92698
PNVDLPPLCSSRFRS

EXOSC8

81

Q96B26
PCLQDASSDQRPVVP

IPPK

411

Q9H8X2
PCSLEIARAPSPRTD

ANKS1B

466

Q7Z6G8
PRQARPTIACLEPAE

FHDC1

576

Q9C0D6
ASCPVLDLRRPPSDL

NCOR2

2166

Q9Y618
SPAPCLLQCPVDTRE

DGKK

176

Q5KSL6
PPDSRRPSEIVIGQC

HRG

91

P04196
ERASLLRQVRPPSCP

LDOC1

36

O95751
PPSPTRTRGNCAEAE

NEUROG3

36

Q9Y4Z2
PSRPESVNDLFLCPQ

IFNLR1

281

Q8IU57
GNDVPDCRRTISAPV

MDM4

356

O15151
ENCSSPAPREELVPA

ITPR1

2511

Q14643
CQPLRLPACSARPDT

KMT5C

301

Q86Y97
PLVTTPAPETCEGRN

CD164

51

Q04900
CQRSLTEDPPPATDL

GLP1R

46

P43220
TEDPPPATDLFCNRT

GLP1R

51

P43220
AVPRATCCPDVQPEE

GMIP

951

Q9P107
SDTQSERGCPLPRAP

KCNK4

351

Q9NYG8
CKNFTPPPRRADEAL

JAG2

1151

Q9Y219
CDVQPPRLGFSRVPD

CELF2-AS1

136

Q8N7Q2
EPAEENLCVTSRRPP

ADAMTSL1

641

Q8N6G6
IRTAREAPSECVCPP

COL23A1

106

Q86Y22
QSEQLRCETSPRPTP

PLXNB1

1211

O43157
NCTEPVSLAPPARPR

PLXNC1

86

O60486
ARDPAPTNFPLRCQK

FAM157A

326

C9JC47
TPRNETRVPCSTVPV

MUC2

5066

Q02817
PEPEQDCAARAPVRA

MYLK3

456

Q32MK0
PPRPSADLILNRCSE

NCF1

366

P14598
CIPAPDPDAVARASR

EVPL

466

Q92817
DVDPDFAPQSRPRSC

FOXO6

11

A8MYZ6
TAFECEPQALRRPPG

GPR153

506

Q6NV75
VEAILARPDPCAPAA

NOTO

51

A8MTQ0
AAAPEVSEEPRCPRA

NOTCH3

1376

Q9UM47
PLQVCPQACPSASER

DLG5

876

Q8TDM6
PPRQEAFRLCGSAIP

LRP3

111

O75074
RPSATTQCPVLRPEE

IL17C

81

Q9P0M4
RQSVQPSETCPPARR

KDM5B

216

Q9UGL1
SASCTRPPSAPRDLQ

EPHA10

331

Q5JZY3
RPNTQGPTCSEPARD

LAMA5

851

O15230
RGEIRDACAETPTPP

CRLF2

211

Q9HC73
PDLPRPEVCFIGRSN

GTPBP8

106

Q8N3Z3
PCLRRGSLPDTQPSQ

KIF18B

656

Q86Y91
PPVTRCNFTPQETLR

KIR3DX1

306

Q9H7L2
STCPFRQPLARPNTL

NUP155

371

O75694
VVDPACVRCRPLTPE

NPC1

971

O15118
PPSCPRTIQVSDFVR

FKBP9

156

O95302
EPLRPRCRPINATLA

CGB2

21

Q6NT52
RAFTCLPVENPEAPV

FCSK

106

Q8N0W3
SCSPPALEPEAVIRA

GAL3ST1

51

Q99999
RARDPAPTNFPLKCQ

FAM157B

326

P0CG42
QPSPARAPAELEVEC

PMAIP1

11

Q13794
PDEETGSPCRLLRQP

BRME1

71

Q0VDD7
RRNTIAPNCALPPVA

GFRA3

231

O60609
VPDCLRADVRVPPSE

ENPP3

661

O14638
ASDRRASCERVSPPP

DBNDD2

21

Q9BQY9
RPRSCEVPGINIFPS

CRTC2

241

Q53ET0
FDDPRLESCQIIPPA

FRMPD4

61

Q14CM0
SLQRSLGPDTRPPEC

GALNT6

151

Q8NCL4
GLPPREPVLSCRSNT

CNTFR

106

P26992
SDGSRQAPRTEPPCV

CRYBG2

121

Q8N1P7
CPQCTDQPFRPSLSR

CRIM1

731

Q9NZV1
NPCNSSVPRDLRRPA

ADCY9

961

O60503
LTSQPEVDERPCRTP

DENND5A

1066

Q6IQ26
EVDERPCRTPPLQQS

DENND5A

1071

Q6IQ26
LRDSRSPVEVFVPPC

ELF2

111

Q15723
RAVPTQCDVPPNSRF

GAA

76

P10253
CQLPESPAERAPERR

LTBP3

1121

Q9NS15
PSECQEPSSSRPSRI

FCRL3

616

Q96P31
SNCEVPRPSTAPQRV

MARK2

551

Q7KZI7
VSHPCRQPDTPTELR

GSTZ1

201

O43708
ENVCDVPPLSRARPV

MAST4

1491

O15021
DVRSPATPACRRDLP

CDCA2

306

Q69YH5
LVASACPARPQIFRP

DGKD

591

Q16760
ISATPPNAVDRPCLR

EFNA2

151

O43921
ADPVEPACGVSRRPS

FAM110B

241

Q8TC76
TRDPTVEFPPDLCSR

DYNC1H1

3681

Q14204
RGPEASVTQTPVCPR

COL7A1

1036

Q02388
RCPQCPQVRAAAAAP

DCBLD2

11

Q96PD2
CPLEAAPLPAEVRES

DIP2A

6

Q14689
CNPPVPTVSSRGREQ

FAM161A

511

Q3B820
ESDAESLSPCPPQRR

FAM53C

216

Q9NYF3
PETRENVCPDASRPL

RSC1A1

536

Q92681
SPQALPSRARAPATC

PRR18

76

Q8N4B5
NAPIPEPRTIFFCER

CDH1

591

P12830
SEPRPPCRDRVVEES

C9

136

P02748
PDSVRTNICPFREDP

IL17RC

351

Q8NAC3
APDDRTRTPLEPSNC

LRRFIP1

396

Q32MZ4
LSRAVSPQCPEEPRA

MICAL2

1211

O94851
PAACIPTQPDARLTA

PKD1

1301

P98161
EEEGCASIRLSPNRP

PKD1

2456

P98161
GCPRTPTTLREASDP

PKN3

476

Q6P5Z2
PSPRPESCLRFGEVA

OTOG

2476

Q6ZRI0
VRSPISCPPLNETEC

OTOG

2801

Q6ZRI0
RRCSDPAGQPSNLLP

GOLGA8A

41

A7E2F4
TCRSFELQPPERSPS

SYT6

36

Q5T7P8
QCRADQSFTSPPPRD

TAF9B

76

Q9HBM6
QCRADQSFTSPPPRD

TAF9

76

Q16594
APELAPTPARCDQDV

SPRY4

71

Q9C004
ESTRNVIELCCPPDP

TRMT2B

456

Q96GJ1
TPQRRSCFESSPDPE

SRRM2

866

Q9UQ35
LREPCDVAPSSRPAQ

TATDN2

26

Q93075
CPSCRREAPEEQSPS

SSPOP

5041

A2VEC9
AVECPPPRTTARLLD

KARS1

431

Q15046
RNIFLPATRPPCVEE

NHS

211

Q6T4R5
EALSPLSPCSPRVNA

NHS

1571

Q6T4R5
QDPPCPRLSRELVEV

NBPF19

491

A0A087WUL8
ERIATRSPDPIPLCT

PRDM15

16

P57071
RNEPAIRNSLPPCSR

FBXL18

501

Q96ME1
EPCALAPNPSSERRS

PRR23B

196

Q6ZRT6
SSQARPPDPLCLCRE

PRR14

101

Q9BWN1
DRERPQPAPCTVGFV

SLITRK3

886

O94933
LRAPPEPADSLTEAC

HIP1

711

O00291
VPTPRPGACITNSAR

SEMA4B

391

Q9NPR2
QDSFVEVSPVCPRPR

SEMA4B

811

Q9NPR2
TAPAVEAPVERRPCC

PPP1R16A

511

Q96I34
RPCIPRFVQLSTAPA

PRODH

11

O43272
DAALCTSPRPRPAVA

SHROOM1

76

Q2M3G4
RAPPTRSQTNCCLPE

SHISA2

196

Q6UWI4
RPLVCESPAERPRDS

WHAMM

686

Q8TF30
CSVLQADPSRIPAPR

WDR18

151

Q9BV38
LNLTSGPEPARDIRC

WIZ

1031

O95785
SPPRDARPLTAAEQA

PKN1

916

Q16512
PEDVALCSSRRPVRP

SCRIB

1606

Q14160
LAPTSQSLRCAPQPR

SOWAHD

16

A6NJG2
QSLRCAPQPRPSRAD

SOWAHD

21

A6NJG2
CSPRNPLEPFASLEQ

JADE1

391

Q6IE81
GTPFRARDEQPCAPT

TBC1D3L

516

B9A6J9
TVQRARSPPFECRIP

PROB1

366

E7EW31
ECRIPSEVPSRAVRP

PROB1

376

E7EW31
RSCVNAIPDQCSPLP

PROS1

111

P07225
RAPEPLATCTQPRKR

SKI

441

P12755
PCVQQDDPRASSPNR

TRIOBP

381

Q9H2D6
DLIPRDRPFVCAPSS

TGFBR1

76

P36897
IEDCPINNPRSGRSP

APC

2661

P25054
PRLACAQPVRVNPTD

CHRD

831

Q9H2X0
LERQPRDSPFCAPSN

C11orf87

131

Q6NUJ2
RRPPSAATTCDPVVE

VGLL4

196

Q14135
TEECLRERPSTCPPR

RECQL5

821

O94762
VERPLTPAPRSCIID

TNRC18

2141

O15417
AAAPEPACRQDTPTL

ZNF750

656

Q32MQ0
CDRTPPEPAATLCEQ

TRIM67

211

Q6ZTA4
ATERERQTSPDPCPQ

ZC3H12A

91

Q5D1E8
AIRNLREGTCPEAPT

TF

341

P02787
PLCRLIPDENPSSFS

RNF125

171

Q96EQ8
SRAIQECRSPVPPPA

SPEG

601

Q15772
PSAAARSPEQLCAPA

SAPCD2

151

Q86UD0
CTRPSDFQAPRNPTL

TNS4

326

Q8IZW8
LCREERRPQPTPTAV

KCTD15

261

Q96SI1
TPCVPRAEEEAASLP

SCN10A

1876

Q9Y5Y9
TLTPRACGRQPQEPS

TSPAN32

236

Q96QS1
DERIPDRSQCTSPQP

STOX2

161

Q9P2F5
APNPPTIREELCTAS

MID1

381

O15344
VALPPAAVNAQPRCS

TOLLIP

216

Q9H0E2
PDCSAVAPPEDLRVA

TNR

321

Q92752
DSSPQRCSPAREPQA

HIVEP3

1991

Q5T1R4
APASCLPESSNDRPV

ZDBF2

186

Q9HCK1
AEPRPLESCCRSEPE

TROAP

551

Q12815
SPLQSPRGLCVDPTR

ZBED10P

121

Q96FA7
PSSQRIQRCLSDPGP

SLC9A1

786

P19634
SDPRSTQPVPRFDCV

SOCS3

106

O14543
SPGLEPEPCSRARSQ

RPS6KL1

11

Q9Y6S9
TPETLVQPGTPARRC

TESK1

421

Q15569
ATCPPCPEAERQLER

SNX19

86

Q92543
REAVTLSRDCPVPLP

PTGR3

46

Q8N4Q0
VDCNNAPLPRALPST

RET

1041

P07949
VERNPDPAISVAPAR

ZNF688

136

P0C7X2
RPQDCPISRVDTFPQ

FTSJ1

291

Q9UET6
LVQPLFPESRPCSDD

VWA5B2

391

Q8N398
VQREPARDAAPSIPA

WFIKKN1

281

Q96NZ8
ARDAAPSIPAPAECL

WFIKKN1

286

Q96NZ8
SRESCEDACPVPRTP

WFIKKN1

401

Q96NZ8
TAEVRAPCSPARGPE

ZKSCAN4

36

Q969J2
PVARRSSEPQLCPGS

SH2D3C

441

Q8N5H7
AVPQEALSSSPRCEP

SP140

176

Q13342
PACEPSRQPPRAAAE

TXLNB

646

Q8N3L3
CSPQARPAAIRQCIP

THSD7B

1461

Q9C0I4
APNPPSIREELCTAS

MID2

401

Q9UJV3
PEGCQPLVSSAVDRR

TREML1

56

Q86YW5
RCAACPRTFPEPAQL

ZNF579

101

Q8NAF0
ESPRCPLPFNASEVV

TG

1211

P01266
PECRRTFAEPALAPS

TRIM62

51

Q9BVG3
DTVLPSPIRSDEPAC

ZDHHC18

361

Q9NUE0
EPCREPLASPIQDSV

ZNF669

76

Q96BR6
PTALATCIPEDRAPV

UTF1

226

Q5T230
VPFCPVRQADSDLQP

ZNF518B

811

Q9C0D4
TGPRLPPEDLVQTRC

KLF5

76

Q13887
RRSPCTISELPPIDA

NAPEPLD

166

Q6IQ20
CRLAFEDESPPAPAR

GRIN2D

1046

O15399