Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent protein disaggregase activity

HSPA1A HSPA1B HSPA8

1.09e-066773GO:0140545
GeneOntologyMolecularFunctionC3HC4-type RING finger domain binding

HSPA1A HSPA1B HSPA8

1.09e-066773GO:0055131
GeneOntologyMolecularFunctionATP-dependent protein folding chaperone

HSPA1A HSPA1B HSPA6 HSPA8

1.68e-0540774GO:0140662
GeneOntologyMolecularFunctionprotein-containing complex destabilizing activity

HSPA1A HSPA1B HSPA8

2.43e-0515773GO:0140776
GeneOntologyMolecularFunctiondenatured protein binding

HSPA1A HSPA1B

4.39e-053772GO:0031249
GeneOntologyMolecularFunctiondeath receptor agonist activity

HSPA1A HSPA1B

1.46e-045772GO:0038177
GeneOntologyMolecularFunctionprotein folding chaperone

HSPA1A HSPA1B HSPA6 HSPA8

1.82e-0473774GO:0044183
GeneOntologyMolecularFunctionheat shock protein binding

AHR HSPA1A HSPA1B HSPA6 HSPA8

4.19e-04163775GO:0031072
GeneOntologyMolecularFunctiondisordered domain specific binding

MDM2 HSPA1A HSPA1B

4.56e-0439773GO:0097718
GeneOntologyMolecularFunctionaxon guidance receptor activity

ROBO1 ROBO2

1.11e-0313772GO:0008046
GeneOntologyMolecularFunctionunfolded protein binding

HSPA1A HSPA1B HSPA6 HSPA8

1.43e-03126774GO:0051082
GeneOntologyMolecularFunctiontranscription coregulator activity

IL31RA DYRK1A EWSR1 TRRAP HSPA1A TOX2 HSPA1B JMJD1C

1.43e-03562778GO:0003712
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCA1 ATP7A HELQ HSPA1A HSPA1B HSPA6 HSPA8

1.55e-03441777GO:0016887
GeneOntologyMolecularFunctionE-box binding

MAX AHR CLOCK

1.69e-0361773GO:0070888
GeneOntologyBiologicalProcesscellular heat acclimation

HSPA1A HSPA1B HSPA6

9.92e-076773GO:0070370
GeneOntologyBiologicalProcessheat acclimation

HSPA1A HSPA1B HSPA6

1.73e-067773GO:0010286
GeneOntologyBiologicalProcessDNA damage response

SETD2 EYA4 BRCA2 UBR5 RADX USP28 TP63 DYRK1A DCLRE1A MDM2 TRRAP HELQ CLOCK HSPA1A HSPA1B

2.17e-069597715GO:0006974
GeneOntologyBiologicalProcesstissue morphogenesis

SETD2 ATP7A GLI3 TP63 LAMA1 AHR ROBO1 ROBO2 SIX4 MDM2 PLXNA1 MAP3K1 LUZP1

3.76e-067507713GO:0048729
GeneOntologyBiologicalProcessprotein refolding

HSPA1A HSPA1B HSPA6 HSPA8

4.57e-0630774GO:0042026
GeneOntologyBiologicalProcesschaperone cofactor-dependent protein refolding

HSPA1A HSPA1B HSPA6 HSPA8

8.61e-0635774GO:0051085
GeneOntologyBiologicalProcessregulation of cell cycle

PTPN3 SETD2 CCNDBP1 BRCA2 USP28 TP63 CDK19 MDM2 MAP10 WNK1 TRRAP CLOCK HSPA1A HSPA1B HSPA8 MYO16

1.30e-0512567716GO:0051726
GeneOntologyBiologicalProcessnegative regulation of negative chemotaxis

ROBO1 ROBO2

1.38e-052772GO:0050925
GeneOntologyBiologicalProcesspositive regulation of animal organ morphogenesis

CD34 ROBO1 ROBO2 SIX4

1.64e-0541774GO:0110110
GeneOntologyBiologicalProcess'de novo' post-translational protein folding

HSPA1A HSPA1B HSPA6 HSPA8

1.64e-0541774GO:0051084
GeneOntologyBiologicalProcessmorphogenesis of an epithelium

SETD2 ATP7A GLI3 TP63 LAMA1 AHR ROBO1 SIX4 PLXNA1 MAP3K1 LUZP1

1.80e-056197711GO:0002009
GeneOntologyBiologicalProcessheart development

SETD2 DSG2 ADAMTS6 GLI3 DUSP6 DYRK1A AHR ROBO1 ROBO2 MDM2 WNK1 LUZP1

2.25e-057577712GO:0007507
GeneOntologyBiologicalProcessepithelium development

SETD2 IL31RA ATP7A BRCA2 GLI3 TP63 LAMA1 AHR ROBO1 ROBO2 SIX4 CLOCK USH2A JMJD1C PLXNA1 MAP3K1 LUZP1

2.32e-0514697717GO:0060429
GeneOntologyBiologicalProcess'de novo' protein folding

HSPA1A HSPA1B HSPA6 HSPA8

2.60e-0546774GO:0006458
GeneOntologyBiologicalProcessDNA repair

SETD2 EYA4 BRCA2 UBR5 RADX USP28 DCLRE1A TRRAP HELQ HSPA1A HSPA1B

2.75e-056487711GO:0006281
GeneOntologyBiologicalProcessresponse to organic cyclic compound

SETD2 ABCA1 DSG2 UBR5 TP63 DUSP6 AHR ATF1 MDM2 CLOCK HSPA1A HSPA1B HSPA8 EPHA5

2.94e-0510487714GO:0014070
GeneOntologyBiologicalProcessblood vessel development

SETD2 ATP7A ADAMTS6 GLI3 CD34 LAMA1 AHR ROBO1 ROBO2 MDM2 WNK1 LUZP1 EPHA5

3.65e-059297713GO:0001568
GeneOntologyBiologicalProcessgland development

PTPN3 ATP7A BRCA2 GLI3 TP63 LAMA1 AHR ROBO1 SIX4 PLXNA1

4.17e-055587710GO:0048732
GeneOntologyBiologicalProcessprotein localization to organelle

FSIP2 STAM2 SETD2 BRCA2 UBR5 GLI3 NPAP1 DYRK1A AHR SIX4 MDM2 WNK1 MEAK7 HSPA8

4.56e-0510917714GO:0033365
GeneOntologyBiologicalProcessregulation of extrinsic apoptotic signaling pathway in absence of ligand

JAK3 EYA4 HSPA1A HSPA1B

4.93e-0554774GO:2001239
GeneOntologyBiologicalProcessmorphogenesis of a branching structure

SETD2 GLI3 TP63 LAMA1 AHR SIX4 PLXNA1

5.04e-05258777GO:0001763
GeneOntologyBiologicalProcessvasculature development

SETD2 ATP7A ADAMTS6 GLI3 CD34 LAMA1 AHR ROBO1 ROBO2 MDM2 WNK1 LUZP1 EPHA5

5.63e-059697713GO:0001944
GeneOntologyBiologicalProcessprotein localization to nucleus

UBR5 GLI3 NPAP1 DYRK1A AHR SIX4 MDM2 HSPA8

6.11e-05362778GO:0034504
GeneOntologyBiologicalProcessregulation of cell cycle process

SETD2 BRCA2 USP28 TP63 MDM2 MAP10 WNK1 TRRAP CLOCK HSPA1A HSPA1B MYO16

6.55e-058457712GO:0010564
GeneOntologyBiologicalProcesscirculatory system development

SETD2 ATP7A DSG2 ADAMTS6 GLI3 CD34 DUSP6 LAMA1 DYRK1A AHR ROBO1 ROBO2 MDM2 WNK1 LUZP1 EPHA5

6.98e-0514427716GO:0072359
GeneOntologyBiologicalProcessregulation of cellular response to stress

SETD2 EYA4 BRCA2 RADX DYRK1A MDM2 TRRAP HELQ HSPA1A MEAK7

7.44e-055987710GO:0080135
GeneOntologyBiologicalProcessprotein-DNA complex organization

SETD2 EYA4 RESF1 BRCA2 UBR5 TP63 DYRK1A AHR ZDBF2 TRRAP CLOCK JMJD1C PHC1

7.67e-059997713GO:0071824
GeneOntologyBiologicalProcesscellular response to organic cyclic compound

ABCA1 UBR5 TP63 AHR MDM2 CLOCK HSPA1A HSPA1B HSPA8 EPHA5

8.20e-056057710GO:0071407
GeneOntologyBiologicalProcessregulation of negative chemotaxis

ROBO1 ROBO2

8.21e-054772GO:0050923
GeneOntologyBiologicalProcessnuclear transport

SETD2 UBR5 GLI3 NPAP1 DYRK1A MDM2 WNK1 HSPA8

8.26e-05378778GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

SETD2 UBR5 GLI3 NPAP1 DYRK1A MDM2 WNK1 HSPA8

8.26e-05378778GO:0006913
GeneOntologyBiologicalProcessresponse to steroid hormone

DSG2 UBR5 TP63 MDM2 CLOCK HSPA1A HSPA1B HSPA8

8.72e-05381778GO:0048545
GeneOntologyBiologicalProcesscellular response to lipid

ABCA1 UBR5 TP63 CDK19 AHR CLOCK HSPA1A HSPA1B HSPA8 PHC1 EPHA5

1.00e-047487711GO:0071396
GeneOntologyBiologicalProcesschromatin organization

SETD2 EYA4 RESF1 BRCA2 UBR5 TP63 DYRK1A ZDBF2 TRRAP CLOCK JMJD1C PHC1

1.14e-048967712GO:0006325
GeneOntologyBiologicalProcessregulation of cellular component biogenesis

ABCA1 ATP7A RESF1 UBAP2L STXBP5 DYRK1A AHR ROBO1 ROBO2 SIX4 HSPA1A HSPA1B HSPA8 MAP3K1

1.15e-0411897714GO:0044087
GeneOntologyBiologicalProcessartery development

ADAMTS6 GLI3 ROBO1 ROBO2 LUZP1

1.41e-04133775GO:0060840
GeneOntologyBiologicalProcesscardiac chamber development

ADAMTS6 AHR ROBO1 ROBO2 MDM2 LUZP1

1.42e-04212776GO:0003205
GeneOntologyBiologicalProcesscardiac septum development

ADAMTS6 ROBO1 ROBO2 MDM2 LUZP1

1.46e-04134775GO:0003279
GeneOntologyBiologicalProcessDNA metabolic process

SETD2 EYA4 BRCA2 UBR5 RADX USP28 AHR DCLRE1A ATF1 TRRAP HELQ HSPA1A HSPA1B

1.69e-0410817713GO:0006259
GeneOntologyBiologicalProcesstube development

SETD2 ATP7A GLI3 TP63 CD34 LAMA1 AHR ROBO1 ROBO2 TNRC6C SIX4 WNK1 JMJD1C LUZP1 EPHA5

1.83e-0414027715GO:0035295
GeneOntologyBiologicalProcessregulation of nucleocytoplasmic transport

SETD2 UBR5 GLI3 MDM2 WNK1

1.91e-04142775GO:0046822
GeneOntologyBiologicalProcessanimal organ formation

GLI3 TP63 ROBO1 ROBO2

2.08e-0478774GO:0048645
GeneOntologyBiologicalProcessanimal organ morphogenesis

SETD2 EYA4 GLI3 TP63 CD34 LAMA1 AHR ROBO1 ROBO2 TSHZ1 SIX4 MDM2 USH2A PLXNA1

2.26e-0412697714GO:0009887
GeneOntologyBiologicalProcesschaperone-mediated protein folding

HSPA1A HSPA1B HSPA6 HSPA8

2.29e-0480774GO:0061077
GeneOntologyBiologicalProcesscellular response to heat

HSPA1A HSPA1B HSPA6 HSPA8

2.40e-0481774GO:0034605
GeneOntologyBiologicalProcessresponse to lipid

ABCA1 DSG2 UBR5 TP63 CDK19 AHR MDM2 CLOCK HSPA1A HSPA1B HSPA8 PHC1 EPHA5

2.52e-0411267713GO:0033993
GeneOntologyBiologicalProcessextrinsic apoptotic signaling pathway in absence of ligand

JAK3 EYA4 HSPA1A HSPA1B

2.52e-0482774GO:0097192
GeneOntologyBiologicalProcessmorphogenesis of a branching epithelium

GLI3 TP63 LAMA1 AHR SIX4 PLXNA1

2.53e-04236776GO:0061138
GeneOntologyBiologicalProcessregulation of double-strand break repair via homologous recombination

SETD2 RADX TRRAP HELQ

2.64e-0483774GO:0010569
GeneOntologyBiologicalProcesscellular response to steroid hormone stimulus

UBR5 TP63 CLOCK HSPA1A HSPA1B HSPA8

2.71e-04239776GO:0071383
GeneOntologyBiologicalProcesssignal transduction in absence of ligand

JAK3 EYA4 HSPA1A HSPA1B

2.76e-0484774GO:0038034
GeneOntologyBiologicalProcesscranial skeletal system development

SETD2 GLI3 TP63 SIX4

2.76e-0484774GO:1904888
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

2.85e-047772GO:0070434
GeneOntologyBiologicalProcessnegative regulation of mammary gland epithelial cell proliferation

BRCA2 ROBO1

2.85e-047772GO:0033600
GeneOntologyBiologicalProcessaxon midline choice point recognition

ROBO1 ROBO2

2.85e-047772GO:0016199
GeneOntologyBiologicalProcesscardiac ventricle development

AHR ROBO1 ROBO2 MDM2 LUZP1

3.42e-04161775GO:0003231
GeneOntologyBiologicalProcessintracellular transport

STAM2 SETD2 ABCA1 UBR5 GLI3 ITSN2 NPAP1 DYRK1A MDM2 WNK1 TFG HSPA1A HSPA1B HSPA8 DOP1A

3.68e-0414967715GO:0046907
GeneOntologyBiologicalProcessventricular septum development

ROBO1 ROBO2 MDM2 LUZP1

3.75e-0491774GO:0003281
GeneOntologyBiologicalProcessheart induction

ROBO1 ROBO2

3.80e-048772GO:0003129
GeneOntologyBiologicalProcesspositive regulation of microtubule nucleation

HSPA1A HSPA1B

3.80e-048772GO:0090063
GeneOntologyBiologicalProcesspositive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway

HSPA1A HSPA1B

3.80e-048772GO:0070426
GeneOntologyBiologicalProcessprotein deubiquitination involved in ubiquitin-dependent protein catabolic process

USP28 OTUD7A

3.80e-048772GO:0071947
GeneOntologyBiologicalProcessintrinsic apoptotic signaling pathway by p53 class mediator

BRCA2 USP28 TP63 MDM2

4.08e-0493774GO:0072332
GeneOntologyBiologicalProcesschromatin remodeling

SETD2 RESF1 BRCA2 UBR5 TP63 DYRK1A ZDBF2 CLOCK JMJD1C PHC1

4.21e-047417710GO:0006338
GeneOntologyBiologicalProcesscell morphogenesis

ATP7A STXBP5 GLI3 ITSN2 LAMA1 AHR ROBO1 ROBO2 JMJD1C PLXNA1 MYO16 MAP3K1 EPHA5

4.42e-0411947713GO:0000902
GeneOntologyBiologicalProcessnegative regulation of extrinsic apoptotic signaling pathway in absence of ligand

EYA4 HSPA1A HSPA1B

4.47e-0440773GO:2001240
GeneOntologyBiologicalProcessnegative regulation of signal transduction in absence of ligand

EYA4 HSPA1A HSPA1B

4.47e-0440773GO:1901099
GeneOntologyBiologicalProcessregulation of protein-containing complex assembly

ABCA1 STXBP5 DYRK1A AHR HSPA1A HSPA1B HSPA8 MAP3K1

4.73e-04489778GO:0043254
GeneOntologyBiologicalProcessforebrain development

SETD2 ATP7A GLI3 ROBO1 ROBO2 HSPA8 PLXNA1 EPHA5

4.73e-04489778GO:0030900
GeneOntologyBiologicalProcesskidney development

ADAMTS6 GLI3 AHR ROBO1 ROBO2 SIX4 HSPA8

4.77e-04372777GO:0001822
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

ABCA1 ATP7A RESF1 UBAP2L AHR ROBO1 ROBO2 ATF1 WNK1 HSPA1A HSPA1B HSPA8 PLXNA1 MAP3K1

4.78e-0413667714GO:0051130
GeneOntologyBiologicalProcessspecification of animal organ identity

GLI3 ROBO1 ROBO2

4.81e-0441773GO:0010092
GeneOntologyBiologicalProcessregulation of heart morphogenesis

ROBO1 ROBO2

4.87e-049772GO:2000826
GeneOntologyBiologicalProcessaxon choice point recognition

ROBO1 ROBO2

4.87e-049772GO:0016198
GeneOntologyBiologicalProcessregulation of cytokinesis

SETD2 BRCA2 MAP10 WNK1

5.17e-0499774GO:0032465
GeneOntologyBiologicalProcesscellular response to chemical stress

ATP7A MDM2 WNK1 HSPA1A HSPA1B MEAK7 HSPA8

5.17e-04377777GO:0062197
GeneOntologyBiologicalProcessgland morphogenesis

GLI3 TP63 LAMA1 ROBO1 PLXNA1

5.41e-04178775GO:0022612
GeneOntologyBiologicalProcessendocardial cushion morphogenesis

ROBO1 ROBO2 MDM2

5.93e-0444773GO:0003203
GeneOntologyBiologicalProcessrenal system development

ADAMTS6 GLI3 AHR ROBO1 ROBO2 SIX4 HSPA8

5.94e-04386777GO:0072001
GeneOntologyBiologicalProcessresponse to cobalt ion

ATP7A ATF1

6.07e-0410772GO:0032025
GeneOntologyBiologicalProcessubiquitin-dependent protein catabolic process

STAM2 UBR5 USP28 OTUD7A MDM2 CLOCK HSPA1A HSPA1B MAP3K1

6.20e-04640779GO:0006511
GeneOntologyBiologicalProcessdouble-strand break repair via homologous recombination

SETD2 BRCA2 RADX TRRAP HELQ

6.93e-04188775GO:0000724
GeneOntologyBiologicalProcessmodification-dependent protein catabolic process

STAM2 UBR5 USP28 OTUD7A MDM2 CLOCK HSPA1A HSPA1B MAP3K1

7.00e-04651779GO:0019941
GeneOntologyBiologicalProcessneuron projection guidance

GLI3 LAMA1 ROBO1 ROBO2 PLXNA1 EPHA5

7.01e-04286776GO:0097485
GeneOntologyBiologicalProcessmodification-dependent macromolecule catabolic process

STAM2 UBR5 USP28 OTUD7A MDM2 CLOCK HSPA1A HSPA1B MAP3K1

7.39e-04656779GO:0043632
GeneOntologyBiologicalProcessolfactory bulb interneuron development

ROBO1 ROBO2

7.40e-0411772GO:0021891
GeneOntologyBiologicalProcessregulation of mRNA export from nucleus

SETD2 WNK1

7.40e-0411772GO:0010793
GeneOntologyBiologicalProcessregulation of nucleotide-binding oligomerization domain containing 2 signaling pathway

HSPA1A HSPA1B

7.40e-0411772GO:0070432
GeneOntologyBiologicalProcesssignal transduction by p53 class mediator

BRCA2 USP28 TP63 DYRK1A MDM2

7.44e-04191775GO:0072331
GeneOntologyBiologicalProcessregulation of animal organ morphogenesis

CD34 ROBO1 ROBO2 SIX4

7.68e-04110774GO:2000027
GeneOntologyBiologicalProcessneuron projection morphogenesis

ATP7A STXBP5 GLI3 ITSN2 LAMA1 ROBO1 ROBO2 PLXNA1 MYO16 EPHA5

7.77e-048027710GO:0048812
GeneOntologyBiologicalProcessrecombinational repair

SETD2 BRCA2 RADX TRRAP HELQ

7.98e-04194775GO:0000725
GeneOntologyBiologicalProcessintrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

BRCA2 USP28 TP63

8.15e-0449773GO:0042771
GeneOntologyBiologicalProcessprotein import into nucleus

UBR5 GLI3 NPAP1 DYRK1A HSPA8

8.17e-04195775GO:0006606
GeneOntologyBiologicalProcesscellular response to oxidative stress

ATP7A MDM2 HSPA1A HSPA1B MEAK7 HSPA8

8.24e-04295776GO:0034599
GeneOntologyBiologicalProcesscell recognition

UBAP2L ROBO1 ROBO2 ZP4 HSPA1B

8.75e-04198775GO:0008037
GeneOntologyBiologicalProcessnegative regulation of inclusion body assembly

HSPA1A HSPA1B

8.86e-0412772GO:0090084
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

ATP7A STXBP5 GLI3 ITSN2 LAMA1 ROBO1 ROBO2 PLXNA1 MYO16 EPHA5

9.11e-048197710GO:0120039
GeneOntologyBiologicalProcesssignal transduction in response to DNA damage

BRCA2 USP28 DYRK1A MDM2 CLOCK

9.15e-04200775GO:0042770
GeneOntologyBiologicalProcessintracellular receptor signaling pathway

UBR5 TP63 AHR CLOCK HSPA1A HSPA1B HSPA8

9.22e-04416777GO:0030522
GeneOntologyCellularComponentnuclear protein-containing complex

BRCA2 UBAP2L MAX CDK19 NPAP1 AHR RBM5 ATF1 TRRAP CLOCK HSPA1A HSPA1B JMJD1C HSPA6 HSPA8 PHC1

5.60e-0513778016GO:0140513
GeneOntologyCellularComponentnuclear body

CCNDBP1 RADX USP28 GLI3 MAX DYRK1A EWSR1 MDM2 HSPA1A HSPA1B PHC1 PAPOLG

1.58e-049038012GO:0016604
GeneOntologyCellularComponenttranscription repressor complex

PRDM10 GLI3 MAX MDM2

3.48e-0487804GO:0017053
GeneOntologyCellularComponentCOP9 signalosome

HSPA1A HSPA1B HSPA6

4.13e-0438803GO:0008180
GeneOntologyCellularComponenttranscription regulator complex

PRDM10 GLI3 MAX AHR ATF1 SIX4 MDM2 TRRAP CLOCK

4.49e-04596809GO:0005667
GeneOntologyCellularComponentapical plasma membrane

CBLIF ATP7A CEACAM21 DSG2 CD34 USH2A HSPA1A HSPA1B

5.47e-04487808GO:0016324
HumanPhenoRenal hypoplasia/aplasia

BRCA2 GLI3 TP63 MAX DUSP6 DYRK1A ROBO1 ROBO2 MDM2 TRRAP JMJD1C PLXNA1 PHC1

1.29e-063593913HP:0008678
HumanPhenoCutaneous syndactyly of toes

EBF3 GLI3 TP63 DYRK1A TRRAP

3.33e-0550395HP:0010621
MousePhenoabnormal heart right ventricle wall morphology

ABCA1 DSG2 ADAMTS6 ROBO1 PHC1

4.40e-0652665MP:0031534
MousePhenoabnormal mammary gland morphology

BRCA2 GLI3 TP63 AHR ROBO1 MDM2 HELQ DOP1A

4.47e-06201668MP:0000627
MousePhenoabnormal apocrine gland morphology

BRCA2 GLI3 TP63 AHR ROBO1 MDM2 HELQ DOP1A

4.47e-06201668MP:0013554
MousePhenoabnormal olfactory tract morphology

GLI3 ROBO1 ROBO2

5.54e-068663MP:0005237
MousePhenodecreased spleen weight

JAK3 ATP7A USP28 MDM2 CLOCK PHC1

1.50e-05113666MP:0004953
MousePhenoabnormal spinal cord lateral column morphology

ROBO1 ROBO2

2.20e-052662MP:0009678
MousePhenosmall spleen

JAK3 IL31RA ATP7A BRCA2 USP28 AHR EWSR1 MDM2 CLOCK PHC1

2.33e-054166610MP:0000692
MousePhenoabnormal epidermis stratum basale morphology

BRCA2 GLI3 TP63 CD34

2.66e-0537664MP:0001231
MousePhenospleen hypoplasia

JAK3 IL31RA BRCA2 AHR EWSR1 MDM2

3.04e-05128666MP:0000694
MousePhenoabnormal olfactory cortex morphology

GLI3 ROBO1 ROBO2

4.39e-0515663MP:0005267
MousePhenoheart right ventricle hypertrophy

ABCA1 ADAMTS6 ROBO1 PHC1

4.43e-0542664MP:0000276
MousePhenoincreased classified tumor incidence

CCNDBP1 BRCA2 TP63 CD34 AHR ROBO1 DCLRE1A MDM2 HELQ

7.08e-05381669MP:0010273
MousePhenoabnormal classified tumor incidence

CCNDBP1 BRCA2 TP63 CD34 AHR ROBO1 DCLRE1A MDM2 HELQ

7.52e-05384669MP:0020188
MousePhenoincreased organ/body region tumor incidence

CCNDBP1 BRCA2 TP63 CD34 AHR ROBO1 DCLRE1A MDM2 HELQ

9.33e-05395669MP:0010274
MousePhenoabnormal organ/body region tumor incidence

CCNDBP1 BRCA2 TP63 CD34 AHR ROBO1 DCLRE1A MDM2 HELQ

1.05e-04401669MP:0013152
MousePhenoincreased malignant tumor incidence

CCNDBP1 BRCA2 TP63 AHR ROBO1 DCLRE1A MDM2

1.23e-04237667MP:0002018
MousePhenoabnormal palate morphology

EYA4 ADAMTS6 GLI3 TP63 ROBO1 TSHZ1 LUZP1 PHC1

1.28e-04321668MP:0003755
MousePhenoincreased heart right ventricle size

ABCA1 ADAMTS6 ROBO1 PHC1

1.29e-0455664MP:0010563
MousePhenoabnormal adenoma incidence

CCNDBP1 TP63 AHR DCLRE1A HELQ

1.68e-04110665MP:0020189
MousePhenoincreased adenoma incidence

CCNDBP1 TP63 AHR DCLRE1A HELQ

1.68e-04110665MP:0010383
MousePhenoabnormal thymus weight

JAK3 BRCA2 MDM2 PHC1

1.81e-0460664MP:0004954
MousePhenoabnormal appendicular skeleton morphology

SETD2 ATP7A BRCA2 ADAMTS6 UBAP2L GLI3 TP63 DUSP6 TSHZ1 EWSR1 TOX2 PLXNA1 PHC1

2.41e-048966613MP:0009250
MousePhenoabnormal mouth morphology

EYA4 ADAMTS6 GLI3 TP63 OTUD7A ROBO1 TSHZ1 MDM2 CLOCK LUZP1 PHC1

2.73e-046706611MP:0000452
MousePhenoabnormal spleen weight

JAK3 ATP7A USP28 DUSP6 AHR MDM2 CLOCK PHC1

2.85e-04361668MP:0004951
MousePhenoincreased carcinoma incidence

CCNDBP1 BRCA2 TP63 AHR ROBO1 MDM2

3.27e-04197666MP:0002038
MousePhenorectal prolapse

JAK3 TP63 AHR

3.36e-0429663MP:0000493
MousePhenoabnormal skin adnexa morphology

ATP7A CEACAM21 BRCA2 DSG2 GLI3 TP63 CD34 ITSN2 AHR ROBO1 EWSR1 TNRC6C MDM2 HELQ DOP1A PAPOLG

3.93e-0413416616MP:0010678
MousePhenocleft palate

EYA4 ADAMTS6 GLI3 TP63 ROBO1 LUZP1 PHC1

4.12e-04289667MP:0000111
MousePhenooral cleft

EYA4 ADAMTS6 GLI3 TP63 ROBO1 LUZP1 PHC1

4.29e-04291667MP:0021164
MousePhenoincreased integument system tumor incidence

BRCA2 CD34 MDM2 HELQ

4.50e-0476664MP:0010293
MousePhenoabnormal throat morphology

GLI3 TSHZ1

4.54e-047662MP:0010370
MousePhenoabnormal epiglottis morphology

GLI3 TSHZ1

4.54e-047662MP:0010371
MousePhenoperinatal lethality, complete penetrance

EYA4 ATP7A EBF3 GLI3 TP63 ROBO1 ROBO2 TSHZ1 TNRC6C LUZP1 PHC1

4.58e-047126611MP:0011089
MousePhenoabnormal heart right ventricle size

ABCA1 ADAMTS6 ROBO1 PHC1

4.97e-0478664MP:0010577
MousePhenoabnormal palatal shelf fusion at midline

TP63 TSHZ1 LUZP1 PHC1

5.48e-0480664MP:0009887
MousePhenoabsent epidermis stratum corneum

BRCA2 TP63

6.04e-048662MP:0001241
MousePhenodecreased cell proliferation

JAK3 CCNDBP1 BRCA2 DSG2 UBR5 TP63 CD34 MAX CDK19 DCLRE1A MDM2

6.26e-047396611MP:0000352
MousePhenodecreased thymus weight

JAK3 MDM2 PHC1

6.42e-0436663MP:0004956
MousePhenoabnormal olfactory lobe morphology

EBF3 GLI3 ROBO1 ROBO2 TSHZ1

6.82e-04149665MP:0009944
MousePhenoincreased mammary gland tumor incidence

BRCA2 MDM2 HELQ

7.54e-0438663MP:0010299
MousePhenoabsent radius

GLI3 TP63

7.74e-049662MP:0000553
MousePhenoheart inflammation

DSG2 AHR MAP3K1

8.14e-0439663MP:0001853
MousePhenoincreased tumor incidence

CCNDBP1 BRCA2 TP63 CD34 AHR ROBO1 DCLRE1A MDM2 HELQ

8.16e-04530669MP:0002020
MousePhenoabnormal craniofacial development

SETD2 UBR5 GLI3 TP63 OTUD7A TSHZ1 LUZP1 PHC1

8.38e-04425668MP:0003935
MousePhenoabnormal heart right ventricle morphology

ABCA1 DSG2 ADAMTS6 ROBO1 PHC1

8.39e-04156665MP:0003920
MousePhenoabnormal secondary palate morphology

EYA4 GLI3 TSHZ1 LUZP1 PHC1

9.13e-04159665MP:0013550
MousePhenoabnormal extraembryonic tissue morphology

JAK3 SETD2 ABCA1 ATP7A BRCA2 UBR5 ADAMTS6 TP63 LAMA1 ROBO1 WNK1 TRRAP

9.92e-049086612MP:0002086
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.90e-074793PF14914
DomainLRRC37_N

LRRC37A LRRC37A3 LRRC37A2

2.90e-074793IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A3 LRRC37A2

2.90e-074793IPR029423
DomainLRRC37

LRRC37A LRRC37A3 LRRC37A2

2.90e-074793PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A3 LRRC37A2

2.90e-074793IPR015753
DomainHSP70

HSPA1A HSPA1B HSPA6 HSPA8

5.19e-0716794PF00012
DomainHSP70_2

HSPA1A HSPA1B HSPA6 HSPA8

6.77e-0717794PS00329
DomainHSP70_3

HSPA1A HSPA1B HSPA6 HSPA8

6.77e-0717794PS01036
DomainHSP70_1

HSPA1A HSPA1B HSPA6 HSPA8

6.77e-0717794PS00297
DomainHsp_70_fam

HSPA1A HSPA1B HSPA6 HSPA8

8.67e-0718794IPR013126
Domain-

HSPA1A HSPA6 HSPA8

1.56e-05127932.60.34.10
DomainHSP70_peptide-bd

HSPA1A HSPA6 HSPA8

1.56e-0512793IPR029047
Domain-

HSPA1A HSPA6 HSPA8

2.02e-05137931.20.1270.10
DomainHeat_shock_70_CS

HSPA1A HSPA6 HSPA8

2.02e-0513793IPR018181
DomainHSP70_C

HSPA1A HSPA6 HSPA8

2.02e-0513793IPR029048
Domainzf-RanBP

RBM5 EWSR1 MDM2

1.06e-0422793PF00641
DomainZF_RANBP2_2

RBM5 EWSR1 MDM2

1.21e-0423793PS50199
DomainZF_RANBP2_1

RBM5 EWSR1 MDM2

1.38e-0424793PS01358
DomainUBA-like

UBAP2L USP28 OTUD7A TNRC6C

1.55e-0464794IPR009060
DomainZnf_RanBP2

RBM5 EWSR1 MDM2

1.57e-0425793IPR001876
Domainfn3

IL31RA ROBO1 ROBO2 USH2A EPHA5

6.20e-04162795PF00041
Domain-

RBM5 EWSR1

7.78e-04107924.10.1060.10
DomainFN3

IL31RA ROBO1 ROBO2 USH2A EPHA5

1.13e-03185795SM00060
DomainHLH

EBF3 MAX AHR CLOCK

1.48e-03116794SM00353
DomainFN3

IL31RA ROBO1 ROBO2 USH2A EPHA5

1.55e-03199795PS50853
DomainFN3_dom

IL31RA ROBO1 ROBO2 USH2A EPHA5

1.93e-03209795IPR003961
DomainLaminin_N

LAMA1 USH2A

2.04e-0316792IPR008211
DomainLAMININ_NTER

LAMA1 USH2A

2.04e-0316792PS51117
DomainLaminin_N

LAMA1 USH2A

2.04e-0316792PF00055
DomainLamNT

LAMA1 USH2A

2.04e-0316792SM00136
DomainUIM

STAM2 USP28

3.52e-0321792SM00726
DomainPAS_fold_3

AHR CLOCK

4.22e-0323792IPR013655
DomainZnF_RBZ

RBM5 EWSR1

4.22e-0323792SM00547
DomainPAS_3

AHR CLOCK

4.22e-0323792PF08447
DomainUIM

STAM2 USP28

4.59e-0324792PS50330
DomainPAS

AHR CLOCK

4.98e-0325792PF00989
DomainPAS_fold

AHR CLOCK

4.98e-0325792IPR013767
DomainUIM_dom

STAM2 USP28

4.98e-0325792IPR003903
DomainPAC

AHR CLOCK

5.38e-0326792IPR001610
DomainPAC

AHR CLOCK

5.38e-0326792SM00086
DomainPAC

AHR CLOCK

5.38e-0326792PS50113
DomainIPT

EBF3 PLXNA1

5.79e-0327792SM00429
DomainSAM

TP63 PHC1 EPHA5

6.18e-0388793SM00454
Domain-

IL31RA CEACAM21 EBF3 ROBO1 ROBO2 USH2A PLXNA1 EPHA5

6.88e-036637982.60.40.10
DomainEGF_LAM_2

LAMA1 USH2A

7.12e-0330792PS50027
DomainEGF_LAM_1

LAMA1 USH2A

7.12e-0330792PS01248
DomainUBA

UBAP2L TNRC6C

7.12e-0330792SM00165
DomainTIG

EBF3 PLXNA1

7.59e-0331792PF01833
DomainSAM_DOMAIN

TP63 PHC1 EPHA5

7.63e-0395793PS50105
DomainKinase-like_dom

JAK3 CDK19 DYRK1A WNK1 TRRAP MAP3K1 EPHA5

7.99e-03542797IPR011009
DomainIPT

EBF3 PLXNA1

8.07e-0332792IPR002909
DomainPAS

AHR CLOCK

8.07e-0332792SM00091
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA6 HSPA8

5.26e-0628594M27254
PathwayWP_MAPK_SIGNALING

CACNA2D4 MAX DUSP6 HSPA1A HSPA1B HSPA6 HSPA8 MAP3K1

7.89e-06246598M39597
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CACNA2D4 MAX DUSP6 HSPA1A HSPA1B HSPA6 HSPA8 MAP3K1

1.43e-05267598M10792
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA6 HSPA8

1.84e-0538594M27255
PathwayREACTOME_ATTENUATION_PHASE

HSPA1A HSPA1B HSPA8

1.93e-0513593MM14952
PathwayWP_MAPK_SIGNALING_PATHWAY

MAX DUSP6 HSPA1A HSPA1B HSPA8 MAP3K1

5.34e-05160596MM15990
PathwayWP_APOPTOSIS_MODULATION_BY_HSP70

HSPA1A HSPA1B MAP3K1

5.43e-0518593MM15964
PathwayKEGG_ENDOCYTOSIS

STAM2 MDM2 HSPA1A HSPA1B HSPA6 HSPA8

1.06e-04181596M1519
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

HSPA1A HSPA1B HSPA8

1.16e-0423593MM14953
PathwayWP_PARKINUBIQUITIN_PROTEASOMAL_SYSTEM_PATHWAY

HSPA1A HSPA1B HSPA6 HSPA8

2.18e-0471594M39690
PathwayKEGG_MEDICUS_VARIANT_AMPLIFIED_MYCN_TO_TRANSCRIPTIONAL_ACTIVATION

MAX MDM2

2.56e-046592M47444
PathwayWP_MEASLES_VIRUS_INFECTION

JAK3 HSPA1A HSPA1B HSPA6 HSPA8

2.56e-04136595M42547
PathwayREACTOME_HSF1_ACTIVATION

HSPA1A HSPA1B HSPA6

2.88e-0431593M27252
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

HSPA1A HSPA1B HSPA6 HSPA8

3.79e-0482594M27250
PathwayKEGG_ANTIGEN_PROCESSING_AND_PRESENTATION

HSPA1A HSPA1B HSPA6 HSPA8

4.97e-0488594M16004
PathwayREACTOME_REGULATION_OF_COMMISSURAL_AXON_PATHFINDING_BY_SLIT_AND_ROBO

ROBO1 ROBO2

7.58e-0410592M27348
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

HSPA1A HSPA1B HSPA6 HSPA8

8.35e-04101594M27253
Pubmed

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

SETD2 BRCA2 UBR5 USP28 CDK19 RBM5 DCLRE1A EWSR1 HSPA1A JMJD1C LUZP1 PHC1

6.48e-10453811229656893
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

STAM2 SETD2 RESF1 BRCA2 UBR5 RADX USP28 MAX ZDBF2 MDM2 WNK1 LUZP1 PAPOLG

1.06e-09588811338580884
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

PRDM10 EYA4 UBR5 EBF3 USP28 MAX DYRK1A TSHZ1 ATF1 QSER1 SIX4 MDM2 TRRAP JMJD1C HSPA8

1.19e-09857811525609649
Pubmed

Reciprocal regulation of human immunodeficiency virus-1 gene expression and replication by heat shock proteins 40 and 70.

HSPA1A HSPA1B HSPA6 HSPA8

3.41e-09981421763498
Pubmed

Specific incorporation of heat shock protein 70 family members into primate lentiviral virions.

HSPA1A HSPA1B HSPA6 HSPA8

5.67e-091081411932435
Pubmed

gp120 neurotoxicity fails to induce heat shock defenses, while the over expression of hsp70 protects against gp120.

HSPA1A HSPA1B HSPA6 HSPA8

5.67e-091081412832005
Pubmed

Human immunodeficiency virus type 1 interaction with the membrane of CD4+ cells induces the synthesis and nuclear translocation of 70K heat shock protein.

HSPA1A HSPA1B HSPA6 HSPA8

5.67e-09108147906708
Pubmed

Identification and characterization of a novel human methyltransferase modulating Hsp70 protein function through lysine methylation.

HSPA1A HSPA1B HSPA6 HSPA8

5.67e-091081423921388
Pubmed

Stress-induced localization of HSPA6 (HSP70B') and HSPA1A (HSP70-1) proteins to centrioles in human neuronal cells.

HSPA1A HSPA1B HSPA6

1.22e-08381324061851
Pubmed

Electrophoretic and immunocytochemical analysis of Hsp72 and Hsp73 expression in heat-stressed mouse testis and epididymis.

HSPA1A HSPA1B HSPA8

1.22e-08381323352621
Pubmed

Stored of Hsp72/Hsp73 in germinal vesicle-stage mouse oocytes.

HSPA1A HSPA1B HSPA8

1.22e-08381315129916
Pubmed

Functional analysis of HSPA1A and HSPA8 in parturition.

HSPA1A HSPA1B HSPA8

1.22e-08381328025138
Pubmed

HIV-1 viral protein R (Vpr) and its interactions with host cell.

HSPA1A HSPA1B HSPA6 HSPA8

1.33e-081281419275587
Pubmed

Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.

UBR5 HSPA1A HSPA1B HSPA6 HSPA8

1.86e-083581519287380
Pubmed

Heat-shock protein 70 can replace viral protein R of HIV-1 during nuclear import of the viral preintegration complex.

HSPA1A HSPA1B HSPA6 HSPA8

3.65e-081581410964507
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ZBTB44 SETD2 EYA4 MAX RBM5 DCLRE1A EWSR1 ATF1 QSER1 SIX4 TRRAP CLOCK HSPA1B JMJD1C HSPA6 HSPA8

4.23e-081294811630804502
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A3 LRRC37A2

4.86e-08481322419166
Pubmed

Association analysis of heat shock protein 70 gene polymorphisms in schizophrenia.

HSPA1A HSPA1B HSPA8

4.86e-08481318299791
Pubmed

Delayed temporal increase of hepatic Hsp70 in ApoE knockout mice after prenatal arsenic exposure.

HSPA1A HSPA1B HSPA8

4.86e-08481322956628
Pubmed

Upregulation of the constitutively expressed HSC70 by KLF4.

HSPA1A HSPA1B HSPA8

4.86e-08481318379898
Pubmed

Clathrin facilitates the morphogenesis of retrovirus particles.

HSPA1A HSPA1B HSPA6 HSPA8

4.86e-081681421738476
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

RESF1 BRCA2 UBR5 ZDBF2 HSPA1A HSPA1B JMJD1C HSPA6 LUZP1 PHC1

4.96e-08418811034709266
Pubmed

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing.

HSPA1A HSPA1B HSPA8

1.21e-07581311584023
Pubmed

Editing-defective tRNA synthetase causes protein misfolding and neurodegeneration.

HSPA1A HSPA1B HSPA8

1.21e-07581316906134
Pubmed

Small kinetochore associated protein (SKAP) promotes UV-induced cell apoptosis through negatively regulating pre-mRNA processing factor 19 (Prp19).

HSPA1A HSPA6 HSPA8

1.21e-07581324718257
Pubmed

Molecular mechanism of mutant p53 stabilization: the role of HSP70 and MDM2.

TP63 MDM2 HSPA1B

1.21e-07581323251530
Pubmed

HDJC9, a novel human type C DnaJ/HSP40 member interacts with and cochaperones HSP70 through the J domain.

HSPA1A HSPA1B HSPA8

1.21e-07581317182002
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

DSG2 UBAP2L ROBO1 ZDBF2 HSPA1A JMJD1C HSPA8 LUZP1

1.56e-0725681833397691
Pubmed

Zic2-dependent axon midline avoidance controls the formation of major ipsilateral tracts in the CNS.

ROBO1 ROBO2 PLXNA1 EPHA5

2.34e-072381424360543
Pubmed

The diverse members of the mammalian HSP70 machine show distinct chaperone-like activities.

HSPA1A HSPA1B HSPA6 HSPA8

2.34e-072381421231916
Pubmed

Genetic aspects of the hsp70 multigene family in vertebrates.

HSPA1A HSPA1B HSPA8

2.42e-0768137988674
Pubmed

Phosphorylation and binding partner analysis of the TSC1-TSC2 complex.

HSPA1A HSPA1B HSPA8

2.42e-07681315963462
Pubmed

BAG-1 modulates the chaperone activity of Hsp70/Hsc70.

HSPA1A HSPA1B HSPA8

2.42e-0768139305631
Pubmed

RING finger protein RNF207, a novel regulator of cardiac excitation.

HSPA1A HSPA1B HSPA8

2.42e-07681325281747
Pubmed

Heat shock factor 2 is activated during mouse heart development.

HSPA1A HSPA1B HSPA8

2.42e-07681311032181
Pubmed

Requirement for a kinase-specific chaperone pathway in the production of a Cdk9/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription.

HSPA1A HSPA1B HSPA6 HSPA8

2.80e-072481410617616
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

FSIP2 SETD2 UBAP2L EWSR1 QSER1 WNK1 HSPA1A HSPA1B HSPA8

3.96e-0739981935987950
Pubmed

Control of mRNA decay by heat shock-ubiquitin-proteasome pathway.

HSPA1A HSPA1B HSPA8

4.23e-07781310205060
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

BRCA2 QSER1 TRRAP JMJD1C

4.60e-072781423395962
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

SETD2 EYA4 DSG2 UBAP2L EWSR1 MDM2 HSPA1B HSPA6 HSPA8

6.19e-0742181934650049
Pubmed

Discovery and refinement of loci associated with lipid levels.

SETD2 ABCA1 BRCA2 RBM5 JMJD1C MAP3K1 PHC1

6.51e-0721181724097068
Pubmed

Function and regulation of heat shock factor 2 during mouse embryogenesis.

HSPA1A HSPA1B HSPA8

6.76e-0788139122205
Pubmed

PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments.

ROBO1 ROBO2 PLXNA1

6.76e-07881325485759
Pubmed

Identification of Redox and Glucose-Dependent Txnip Protein Interactions.

HSPA1A HSPA1B JMJD1C HSPA8

9.34e-073281427437069
Pubmed

Identification of proximal SUMO-dependent interactors using SUMO-ID.

RESF1 BRCA2 UBAP2L HSPA1A JMJD1C HSPA6 HSPA8 LUZP1 PAPOLG

9.62e-0744481934795231
Pubmed

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

JAK3 STAM2 UBR5 UBAP2L MAX ITSN2 DYRK1A HSPA8

9.94e-0732781815592455
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

ZBTB44 EYA4 EBF3 DYRK1A ATF1 ZDBF2 SIX4 HSPA1A HSPA1B HSPA8

1.05e-06583811029844126
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

SETD2 RADX RBM5 ROBO1 DCLRE1A ZDBF2 QSER1 WNK1 TFG JMJD1C PAPOLG

1.07e-06733811134672954
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

UBR5 MAX WNK1 TRRAP HSPA1A HSPA6 HSPA8

1.34e-0623581730258100
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A3 LRRC37A2

1.44e-061081323064749
Pubmed

The Eyes Absent family members EYA4 and EYA1 promote PLK1 activation and successful mitosis through tyrosine dephosphorylation.

EYA4 RESF1 BRCA2 EWSR1 TNRC6C JMJD1C

1.56e-0615281638360978
Pubmed

ARD1-mediated Hsp70 acetylation balances stress-induced protein refolding and degradation.

HSPA1A HSPA1B HSPA8

1.98e-061181327708256
Pubmed

Binding of human nucleotide exchange factors to heat shock protein 70 (Hsp70) generates functionally distinct complexes in vitro.

HSPA1A HSPA1B HSPA8

1.98e-061181324318877
Pubmed

Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes.

UBR5 HSPA1A HSPA6 HSPA8

2.59e-064181432723828
Pubmed

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.

HSPA1A HSPA1B HSPA8

2.64e-061281312150907
Pubmed

A CASPR1-ATP1B3 protein interaction modulates plasma membrane localization of Na+/K+-ATPase in brain microvascular endothelial cells.

HSPA1A HSPA1B HSPA8

3.42e-061381330792309
Pubmed

UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome.

HSPA1A HSPA1B HSPA8

3.42e-061381327477512
Pubmed

BMI1-UBR5 axis regulates transcriptional repression at damaged chromatin.

UBR5 UBAP2L PHC1

3.42e-061381327647897
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

DSG2 UBAP2L RBM5 EWSR1 HSPA1A HSPA8 LUZP1

3.69e-0627481734244482
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RESF1 ROBO2 ZDBF2 TNRC6C MEAK7

4.02e-0610181510997877
Pubmed

Human transcription factor protein interaction networks.

EYA4 RESF1 UBAP2L RADX GLI3 MAX EWSR1 ATF1 QSER1 TNRC6C SIX4 MDM2 TRRAP JMJD1C

5.08e-061429811435140242
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SETD2 TRRAP HSPA1A HSPA6 HSPA8 PLXNA1

5.18e-0618781626460568
Pubmed

Exercise induces hepatosplanchnic release of heat shock protein 72 in humans.

HSPA1A HSPA1B

5.36e-06281212411538
Pubmed

Molecular cloning and analysis of DNA complementary to three mouse Mr = 68,000 heat shock protein mRNAs.

HSPA1A HSPA1B

5.36e-0628122868009
Pubmed

Up-regulation of inducible heat shock protein-70 expression in multiple sclerosis patients.

HSPA1A HSPA1B

5.36e-06281224328534
Pubmed

In vitro transcription of a human hsp 70 heat shock gene by extracts prepared from heat-shocked and non-heat-shocked human cells.

HSPA1A HSPA1B

5.36e-0628123786141
Pubmed

Establishment and characterization of a clear cell odontogenic carcinoma cell line with EWSR1-ATF1 fusion gene.

EWSR1 ATF1

5.36e-06281228559020
Pubmed

Processing of U14 small nucleolar RNA from three different introns of the mouse 70-kDa-cognate-heat-shock-protein pre-messenger RNA.

HSPA1B HSPA8

5.36e-0628127813466
Pubmed

Characterization of the binding between a 70-kDa heat shock protein, HspA1A, and phosphoinositides.

HSPA1A HSPA1B

5.36e-06281226923070
Pubmed

Soluble heat shock protein 70 members in patients undergoing allogeneic hematopoietic cell transplantation.

HSPA1A HSPA6

5.36e-06281227020764
Pubmed

Robo signaling regulates the production of cranial neural crest cells.

ROBO1 ROBO2

5.36e-06281228987541
Pubmed

Surface expression of HSP72 by LPS-stimulated neutrophils facilitates gammadeltaT cell-mediated killing.

HSPA1A HSPA1B

5.36e-06281216482515
Pubmed

Effect of hyaluronan oligosaccharides on the expression of heat shock protein 72.

HSPA1A HSPA1B

5.36e-06281211864979
Pubmed

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis.

TP63 DUSP6

5.36e-06281223246965
Pubmed

Possible Involvement of the Upregulation of ΔNp63 Expression Mediated by HER2-Activated Aryl Hydrocarbon Receptor in Mammosphere Maintenance.

TP63 AHR

5.36e-06281236292946
Pubmed

Hippocampal 72-kDa heat shock protein expression varies according to mice learning performance independently from chronic exposure to stress.

HSPA1A HSPA1B

5.36e-06281215719414
Pubmed

Hsp70 protects from stroke in atrial fibrillation patients by preventing thrombosis without increased bleeding risk.

HSPA1A HSPA1B

5.36e-06281226976620
Pubmed

Maintaining protein stability of ∆Np63 via USP28 is required by squamous cancer cells.

USP28 TP63

5.36e-06281232128997
Pubmed

Targeting membrane heat-shock protein 70 (Hsp70) on tumors by cmHsp70.1 antibody.

HSPA1A HSPA1B

5.36e-06281221187371
Pubmed

Radiation therapy induces circulating serum Hsp72 in patients with prostate cancer.

HSPA1A HSPA1B

5.36e-06281220430459
Pubmed

Astrocyte targeted overexpression of Hsp72 or SOD2 reduces neuronal vulnerability to forebrain ischemia.

HSPA1A HSPA1B

5.36e-06281220235222
Pubmed

Genetic determinants of HSP70 gene expression following heat shock.

HSPA1A HSPA1B

5.36e-06281220876613
Pubmed

The C-terminal BAG domain of BAG5 induces conformational changes of the Hsp70 nucleotide-binding domain for ADP-ATP exchange.

HSPA1A HSPA1B

5.36e-06281220223214
Pubmed

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells.

HSPA1A HSPA1B

5.36e-06281220093776
Pubmed

Bacterial infection elicits heat shock protein 72 release from pleural mesothelial cells.

HSPA1A HSPA1B

5.36e-06281223704948
Pubmed

A Spatiotemporal Sequence of Sensitization to Slits and Semaphorins Orchestrates Commissural Axon Navigation.

ROBO1 ROBO2

5.36e-06281231597096
Pubmed

Structure and expression of the human gene encoding major heat shock protein HSP70.

HSPA1A HSPA1B

5.36e-0628122858050
Pubmed

Nuclear heat shock protein 72 as a negative regulator of oxidative stress (hydrogen peroxide)-induced HMGB1 cytoplasmic translocation and release.

HSPA1A HSPA1B

5.36e-06281217513788
Pubmed

IL-6 activates HSP72 gene expression in human skeletal muscle.

HSPA1A HSPA1B

5.36e-06281212207910
Pubmed

Inducing heat shock protein 70 expression provides a robust antithrombotic effect with minimal bleeding risk.

HSPA1A HSPA1B

5.36e-06281228837204
Pubmed

Concurrent action of purifying selection and gene conversion results in extreme conservation of the major stress-inducible Hsp70 genes in mammals.

HSPA1A HSPA1B

5.36e-06281229572464
Pubmed

Protective effect of heat shock proteins 70.1 and 70.3 on retinal photic injury after systemic hyperthermia.

HSPA1A HSPA1B

5.36e-06281215988927
Pubmed

Knockdown of Heat Shock Proteins HSPA6 (Hsp70B') and HSPA1A (Hsp70-1) Sensitizes Differentiated Human Neuronal Cells to Cellular Stress.

HSPA1A HSPA6

5.36e-06281229090408
Pubmed

UBR5 is a novel regulator of WNK1 stability.

UBR5 WNK1

5.36e-06281235442829
Pubmed

Hsp70 (HSPA1) Lysine Methylation Status as a Potential Prognostic Factor in Metastatic High-Grade Serous Carcinoma.

HSPA1A HSPA1B

5.36e-06281226448330
Pubmed

Molecular genetic characterization of the EWS/ATF1 fusion gene in clear cell sarcoma of tendons and aponeuroses.

EWSR1 ATF1

5.36e-06281211992546
Pubmed

HSP70.1 and -70.3 are required for late-phase protection induced by ischemic preconditioning of mouse hearts.

HSPA1A HSPA1B

5.36e-06281212714332
Pubmed

Inflammation-induced, 3'UTR-dependent translational inhibition of Hsp70 mRNA impairs intestinal homeostasis.

HSPA1A HSPA1B

5.36e-06281219299581
Pubmed

Insights into regulation and function of the major stress-induced hsp70 molecular chaperone in vivo: analysis of mice with targeted gene disruption of the hsp70.1 or hsp70.3 gene.

HSPA1A HSPA1B

5.36e-06281211713291
Pubmed

Heat shock protein 72 (Hsp72) improves long term recovery after focal cerebral ischemia in mice.

HSPA1A HSPA1B

5.36e-06281221108992
InteractionEYA4 interactions

EYA4 RESF1 BRCA2 EWSR1 QSER1 TNRC6C SIX4 JMJD1C LUZP1

5.70e-07243819int:EYA4
InteractionRFPL2 interactions

DYRK1A MDM2 HSPA6 HSPA8

1.68e-0622814int:RFPL2
InteractionSTAM interactions

JAK3 STAM2 USP28 HSPA1A HSPA8 MAP3K1 EPHA5

2.75e-06153817int:STAM
InteractionCCDC117 interactions

HSPA1A HSPA1B HSPA6 HSPA8

3.38e-0626814int:CCDC117
InteractionDNAJB2 interactions

ATP7A HSPA1A HSPA1B HSPA6 HSPA8 MAP3K1

3.46e-06102816int:DNAJB2
InteractionPOU5F1 interactions

RESF1 UBR5 UBAP2L MAX LAMA1 MUC16 EWSR1 TRRAP TOX2 JMJD1C HSPA8 PHC1

3.58e-065848112int:POU5F1
InteractionRPS6KA1 interactions

PTPN3 UBR5 MDM2 TRRAP HSPA1A HSPA6 HSPA8 PAPOLG

3.75e-06228818int:RPS6KA1
InteractionPDLIM4 interactions

ABCA1 EWSR1 HSPA1A HSPA8

3.96e-0627814int:PDLIM4
InteractionKDM1A interactions

RESF1 BRCA2 UBR5 USP28 MAX ITSN2 ZDBF2 TRRAP CLOCK HSPA1A HSPA1B JMJD1C HSPA6 LUZP1 PHC1

4.43e-069418115int:KDM1A
InteractionRCOR1 interactions

RESF1 BRCA2 UBR5 MAX ZDBF2 CLOCK HSPA1A HSPA1B JMJD1C HSPA6 LUZP1

4.43e-064948111int:RCOR1
InteractionCCNI2 interactions

HSPA1B HSPA6 HSPA8

5.16e-069813int:CCNI2
InteractionWWTR1 interactions

STAM2 SETD2 DSG2 TP63 QSER1 TRRAP CLOCK JMJD1C HSPA6 LUZP1

7.27e-064228110int:WWTR1
InteractionFAM50A interactions

STAM2 TP63 EWSR1 TRRAP HSPA1A HSPA8

7.29e-06116816int:FAM50A
InteractionPHF21A interactions

RESF1 BRCA2 UBR5 MAX ZDBF2 CLOCK JMJD1C HSPA6 LUZP1

9.59e-06343819int:PHF21A
InteractionCLTA interactions

ITSN2 DYRK1A TNRC6C WNK1 TFG HSPA1A HSPA1B HSPA6 HSPA8

1.15e-05351819int:CLTA
InteractionFAM83F interactions

HSPA1A HSPA1B HSPA6 HSPA8

1.29e-0536814int:FAM83F
InteractionCIC interactions

ZBTB44 SETD2 EYA4 EBF3 DYRK1A EWSR1 ATF1 ZDBF2 SIX4 HSPA1A HSPA1B HSPA8

1.50e-056738112int:CIC
InteractionDNAJA4 interactions

RADX TRRAP HSPA1A HSPA6 HSPA8

1.65e-0579815int:DNAJA4
InteractionLRRC28 interactions

HSPA1B HSPA6 HSPA8

1.74e-0513813int:LRRC28
InteractionCFAP52 interactions

BRCA2 HSPA1A HSPA8

1.74e-0513813int:CFAP52
InteractionJUN interactions

EYA4 CCNDBP1 EBF3 MAX EWSR1 ATF1 SIX4 MDM2 HSPA8 MAP3K1

1.85e-054708110int:JUN
InteractionCEACAM5 interactions

CEACAM21 EWSR1 TRRAP

2.21e-0514813int:CEACAM5
InteractionFHL2 interactions

DYRK1A AHR RBM5 ATF1 QSER1 MDM2 MAP10 WNK1 HSPA1A

2.99e-05396819int:FHL2
InteractionBRCA1 interactions

BRCA2 UBR5 UBAP2L USP28 TP63 DYRK1A AHR DCLRE1A EWSR1 ATF1 TNRC6C TFG USH2A HSPA8 MAP3K1 LUZP1

3.15e-0512498116int:BRCA1
InteractionRAD23A interactions

ZBTB44 BRCA2 EWSR1 MDM2 HSPA1A HSPA8 MAP3K1

3.30e-05224817int:RAD23A
InteractionTSSK6 interactions

UBR5 MDM2 HSPA1A HSPA8

3.79e-0547814int:TSSK6
InteractionSPDL1 interactions

UBR5 MAX EWSR1 WNK1 TRRAP HSPA1A HSPA6 HSPA8

3.90e-05315818int:SPDL1
InteractionC3orf38 interactions

HSPA1A HSPA6 HSPA8

4.08e-0517813int:C3orf38
InteractionKCNA3 interactions

STAM2 ATP7A DSG2 UBAP2L LAMA1 ROBO1 HELQ HSPA1B JMJD1C HSPA8 LUZP1 DOP1A PAPOLG

4.14e-058718113int:KCNA3
InteractionUBE2D2 interactions

STAM2 EYA4 UBR5 QSER1 MDM2 HSPA8 MAP3K1 LUZP1

4.17e-05318818int:UBE2D2
InteractionMDC1 interactions

SETD2 BRCA2 UBR5 RADX USP28 EWSR1 MDM2 TRRAP PHC1

4.22e-05414819int:MDC1
InteractionSMG7 interactions

UBAP2L RBM5 ZDBF2 TNRC6C SIX4 MDM2 HSPA1A JMJD1C

4.26e-05319818int:SMG7
InteractionTGM2 interactions

ABCA1 LAMA1 DYRK1A WNK1 HSPA1A HSPA1B HSPA8

4.48e-05235817int:TGM2
InteractionHIPK2 interactions

TP63 DYRK1A MDM2 HSPA1A MAP3K1

4.69e-0598815int:HIPK2
InteractionCPSF6 interactions

SETD2 EYA4 UBAP2L TP63 MAX ITSN2 EWSR1 TRRAP HSPA8 PAPOLG

4.80e-055268110int:CPSF6
InteractionGPNMB interactions

IL31RA ITSN2 HSPA8

4.89e-0518813int:GPNMB
InteractionILRUN interactions

HSPA1A HSPA8 MAP3K1

4.89e-0518813int:ILRUN
InteractionDNAJC7 interactions

BRCA2 RADX LAMA1 DYRK1A TRRAP HSPA1A HSPA1B HSPA6 HSPA8

5.17e-05425819int:DNAJC7
InteractionMCRIP2 interactions

EYA4 CCNDBP1 UBAP2L HSPA1A

5.24e-0551814int:MCRIP2
InteractionTP53BP1 interactions

BRCA2 UBR5 USP28 CDK19 RBM5 DCLRE1A EWSR1 HSPA1A JMJD1C HSPA8

5.37e-055338110int:TP53BP1
InteractionPHLPP1 interactions

DSG2 UBAP2L ROBO1 ZDBF2 HSPA1A JMJD1C HSPA8 LUZP1

5.76e-05333818int:PHLPP1
InteractionCEP85 interactions

EYA4 UBAP2L GLI3 EWSR1 TNRC6C MAP3K1

6.14e-05169816int:CEP85
InteractionPMS1 interactions

BRCA2 UBR5 UBAP2L EWSR1 TRRAP

6.53e-05105815int:PMS1
InteractionSENP2 interactions

EYA4 USP28 MDM2 HSPA1A HSPA1B HSPA8

6.55e-05171816int:SENP2
InteractionDYRK2 interactions

UBR5 MDM2 HSPA1A HSPA1B HSPA6 HSPA8

6.99e-05173816int:DYRK2
InteractionEPHA3 interactions

STAM2 CEACAM21 DSG2 HSPA1B EPHA5

8.50e-05111815int:EPHA3
InteractionERBB3 interactions

JAK3 EYA4 DYRK1A MDM2 TFG HSPA1A HSPA1B HSPA8

9.00e-05355818int:ERBB3
InteractionFRMD8P1 interactions

HSPA6 HSPA8

9.52e-054812int:FRMD8P1
InteractionRPLP0P2 interactions

CCNDBP1 EWSR1

9.52e-054812int:RPLP0P2
InteractionTOLLIP interactions

UBR5 DYRK1A ROBO1 WNK1 TFG HSPA1B HSPA8 LUZP1

9.54e-05358818int:TOLLIP
InteractionCOPS5 interactions

ABCA1 CCNDBP1 UBAP2L MAX AHR RBM5 EWSR1 MDM2 WNK1 TFG HSPA1A HSPA1B HSPA6 HSPA8

1.16e-0411028114int:COPS5
InteractionHNF1B interactions

EYA4 EWSR1 ATF1 QSER1 SIX4 TRRAP

1.17e-04190816int:HNF1B
InteractionDCUN1D1 interactions

EWSR1 TFG TRRAP HSPA1A HSPA1B HSPA8 MAP3K1

1.20e-04275817int:DCUN1D1
InteractionAAK1 interactions

EYA4 QSER1 WNK1 HSPA1A LUZP1

1.28e-04121815int:AAK1
InteractionNANOG interactions

RESF1 BRCA2 MAX MUC16 QSER1 TRRAP JMJD1C HSPA8 PHC1

1.33e-04481819int:NANOG
InteractionTNRC6A interactions

EYA4 UBR5 UBAP2L GLI3 ITSN2 TNRC6C WNK1

1.34e-04280817int:TNRC6A
InteractionTTC7A interactions

UBR5 EWSR1 HSPA8

1.35e-0425813int:TTC7A
InteractionBUB1B interactions

BRCA2 UBR5 DYRK1A MDM2 HSPA1A HSPA8

1.35e-04195816int:BUB1B
InteractionCREBBP interactions

EYA4 GLI3 DYRK1A RBM5 EWSR1 ATF1 MDM2 TRRAP CLOCK HSPA8

1.41e-045998110int:CREBBP
InteractionERCC8 interactions

STXBP5 EWSR1 MDM2 HSPA1B HSPA8

1.43e-04124815int:ERCC8
InteractionAARSD1 interactions

BRCA2 DYRK1A WNK1 HSPA1A LUZP1

1.49e-04125815int:AARSD1
InteractionBRCA2 interactions

EYA4 BRCA2 TP63 NCKAP5 EWSR1 MDM2 TRRAP HELQ

1.55e-04384818int:BRCA2
InteractionBAD interactions

EWSR1 WNK1 HSPA1A HSPA6 HSPA8

1.55e-04126815int:BAD
InteractionMAGED1 interactions

JAK3 EYA4 BRCA2 UBR5 GLI3 TFG HSPA1A

1.85e-04295817int:MAGED1
InteractionMED15 interactions

EYA4 UBAP2L CDK19 EWSR1 TRRAP

1.85e-04131815int:MED15
InteractionCNOT3 interactions

UBAP2L GLI3 DYRK1A TNRC6C TRRAP HSPA8

1.87e-04207816int:CNOT3
InteractionEIF2AK1 interactions

MDM2 TRRAP HSPA8

1.91e-0428813int:EIF2AK1
InteractionSIRT6 interactions

SETD2 CCNDBP1 UBR5 UBAP2L DYRK1A AHR ZDBF2 MDM2 TRRAP HSPA8

2.06e-046288110int:SIRT6
InteractionCHTF8 interactions

EYA4 EWSR1 MDM2

2.12e-0429813int:CHTF8
InteractionNR4A1 interactions

EYA4 ROBO2 TFG HSPA1B HSPA8 MAP3K1

2.13e-04212816int:NR4A1
InteractionBCOR interactions

EYA4 UBAP2L RADX GLI3 QSER1 JMJD1C PHC1

2.13e-04302817int:BCOR
InteractionCOPS6 interactions

TP63 EWSR1 TFG HSPA1A HSPA1B HSPA6 HSPA8 MAP3K1

2.33e-04408818int:COPS6
InteractionTNRC6C interactions

EYA4 UBAP2L ITSN2 TNRC6C TFG

2.36e-04138815int:TNRC6C
InteractionKDM5C interactions

BRCA2 MAX EWSR1 TRRAP MAP3K1

2.44e-04139815int:KDM5C
InteractionHEY1 interactions

EWSR1 MDM2 HSPA1A HSPA1B HSPA8

2.53e-04140815int:HEY1
InteractionEPS15 interactions

STAM2 ITSN2 DYRK1A HSPA1A HSPA1B HSPA8

2.59e-04220816int:EPS15
InteractionWDR37 interactions

SETD2 EWSR1 TRRAP HSPA8

2.76e-0478814int:WDR37
InteractionRHOA interactions

ATP7A DSG2 STXBP5 TP63 ROBO1 QSER1 MDM2 TRRAP CLOCK HSPA1A HSPA6 HSPA8 PLXNA1 MAP3K1

2.77e-0411998114int:RHOA
InteractionBAG4 interactions

BRCA2 WNK1 HSPA1A HSPA1B HSPA6 HSPA8

2.86e-04224816int:BAG4
InteractionDNAJB4 interactions

MDM2 HSPA1A HSPA1B HSPA6 HSPA8

2.97e-04145815int:DNAJB4
InteractionFBXO38 interactions

UBR5 QSER1 TRRAP JMJD1C HSPA6

2.97e-04145815int:FBXO38
InteractionILK interactions

UBR5 UBAP2L TP63 EWSR1 HSPA1A HSPA6 HSPA8

2.98e-04319817int:ILK
InteractionANKRD17 interactions

UBAP2L GLI3 ITSN2 TNRC6C MDM2 HSPA1A

3.00e-04226816int:ANKRD17
InteractionRNPS1 interactions

JAK3 SETD2 PRDM10 UBR5 EBF3 TP63 ITSN2 HSPA8

3.07e-04425818int:RNPS1
InteractionGLDC interactions

DSG2 UBAP2L RBM5 EWSR1 HSPA1A HSPA8 LUZP1

3.09e-04321817int:GLDC
InteractionPNPLA5 interactions

HSPA1B HSPA6 HSPA8

3.13e-0433813int:PNPLA5
InteractionSTAM2 interactions

JAK3 STAM2 HSPA1A MAP3K1 EPHA5

3.17e-04147815int:STAM2
InteractionRNF43 interactions

UBR5 RADX GLI3 HSPA1A HSPA1B JMJD1C HSPA6 HSPA8

3.17e-04427818int:RNF43
InteractionFOXJ2 interactions

EYA4 UBR5 TSHZ1 QSER1

3.18e-0481814int:FOXJ2
InteractionPIK3R2 interactions

JAK3 HSPA1A HSPA1B HSPA6 HSPA8 EPHA5

3.29e-04230816int:PIK3R2
InteractionESYT3 interactions

EWSR1 TRRAP

3.31e-047812int:ESYT3
InteractionRNF207 interactions

HSPA1A HSPA8

3.31e-047812int:RNF207
InteractionRYBP interactions

UBAP2L MAX MDM2 HSPA8 LUZP1 PHC1

3.45e-04232816int:RYBP
InteractionTET2 interactions

EYA4 HSPA1A HSPA6 HSPA8 PHC1

3.47e-04150815int:TET2
InteractionNACA interactions

OTUD7A EWSR1 MDM2 TRRAP HSPA1A HSPA8

3.61e-04234816int:NACA
InteractionCDC20 interactions

EYA4 UBR5 TP63 TRRAP HSPA1A HSPA8

3.61e-04234816int:CDC20
InteractionANAPC2 interactions

EYA4 BRCA2 TP63 DYRK1A MDM2 HSPA1A

3.61e-04234816int:ANAPC2
InteractionR3HDM1 interactions

EYA4 UBAP2L EWSR1 HSPA1A

3.66e-0484814int:R3HDM1
InteractionNES interactions

ZBTB44 UBR5 TP63 LAMA1 HSPA8

3.69e-04152815int:NES
InteractionATM interactions

SETD2 BRCA2 USP28 DCLRE1A MDM2 HSPA8 EPHA5

3.85e-04333817int:ATM
Cytoband14q23

MAX SIX4

1.10e-04981214q23
GeneFamilyHeat shock 70kDa proteins

HSPA1A HSPA1B HSPA6 HSPA8

1.91e-0717564583
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RBM5 EWSR1 MDM2

3.60e-052156389
GeneFamilyFibronectin type III domain containing

IL31RA ROBO1 ROBO2 USH2A EPHA5

1.35e-04160565555
CoexpressionKRISHNAN_FURIN_TARGETS_UP

HSPA1A HSPA1B HSPA8

3.36e-0610813MM1243
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

JAK3 ZBTB44 SETD2 RESF1 CCNDBP1 UBR5 DUSP6 ITSN2 DYRK1A AHR TNRC6C WNK1 JMJD1C HSPA8 LUZP1 PAPOLG

1.12e-0514928116M40023
CoexpressionAIZARANI_LIVER_C12_NK_NKT_CELLS_4

HSPA1A HSPA1B HSPA6 HSPA8

1.61e-0549814M39116
CoexpressionGABRIELY_MIR21_TARGETS

ZBTB44 PTPN3 UBR5 ITSN2 WNK1 CLOCK MAP3K1

3.19e-05289817M2196
CoexpressionGSE3982_MEMORY_CD4_TCELL_VS_TH1_UP

SETD2 RESF1 RADX LRRC37A2 JMJD1C PHC1

3.39e-05197816M5378
CoexpressionGSE43863_TH1_VS_LY6C_INT_CXCR5POS_EFFECTOR_CD4_TCELL_DN

ABCA1 RESF1 USP28 CLOCK HSPA1B MAP3K1

3.69e-05200816M9765
CoexpressionGSE7460_CTRL_VS_TGFB_TREATED_ACT_CD8_TCELL_DN

SLC26A8 ABCA1 ADAMTS6 TP63 MAX AHR

3.69e-05200816M5679
CoexpressionMCBRYAN_PUBERTAL_BREAST_5_6WK_DN

RESF1 EBF3 ITSN2 RBM5 WNK1

5.87e-05133815M8880
CoexpressionMCBRYAN_PUBERTAL_BREAST_5_6WK_DN

RESF1 EBF3 ITSN2 RBM5 WNK1

6.75e-05137815MM990
CoexpressionDEN_INTERACT_WITH_LCA5

HSPA1A HSPA1B HSPA8

7.02e-0526813M1380
CoexpressionMCCLUNG_COCAIN_REWARD_4WK

CBLIF DUSP6 DCLRE1A WNK1

8.26e-0574814M1600
CoexpressionMCCLUNG_COCAIN_REWARD_4WK

CBLIF DUSP6 DCLRE1A WNK1

9.17e-0576814MM682
CoexpressionDESCARTES_FETAL_THYMUS_THYMIC_EPITHELIAL_CELLS

PTPN3 EYA4 IL31RA TP63 OTUD7A ROBO2

1.11e-04244816M40312
CoexpressionNOJIMA_SFRP2_TARGETS_UP

HSPA1A HSPA1B HSPA6

1.32e-0432813M14772
CoexpressionGSE7509_UNSTIM_VS_FCGRIIB_STIM_MONOCYTE_DN

PRDM10 STXBP5 TNRC6C WNK1 HELQ

1.67e-04166815M6826
CoexpressionONDER_CDH1_TARGETS_1_DN

BRCA2 TP63 MAX DUSP6 HSPA8

1.86e-04170815M6822
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA2

PTPN3 LRRC37A3 STXBP5 ROBO1 ROBO2 TOX2 DOP1A EPHA5

1.88e-04513818M39069
CoexpressionSAFFORD_T_LYMPHOCYTE_ANERGY

JAK3 DUSP6 HSPA1A HSPA1B

2.36e-0497814MM692
CoexpressionIGARASHI_ATF4_TARGETS_DN

DSG2 CDK19 HSPA1A HSPA1B

2.45e-0498814M4779
CoexpressionMIKKELSEN_DEDIFFERENTIATED_STATE_UP

DSG2 PHC1

2.61e-048812M1924
CoexpressionMIKKELSEN_DEDIFFERENTIATED_STATE_UP

DSG2 PHC1

2.61e-048812MM812
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

PTPN3 UBR5 TP63 DYRK1A AHR DOP1A

3.38e-04300816M8702
CoexpressionGSE13738_RESTING_VS_BYSTANDER_ACTIVATED_CD4_TCELL_UP

ZBTB44 ADAMTS6 RADX LRRC37A2 TSHZ1

3.43e-04194815M3321
CoexpressionHELLER_SILENCED_BY_METHYLATION_DN

USH2A HSPA1A HSPA1B HSPA6

3.43e-04107814M3185
CoexpressionPARK_HSC_MARKERS

CCNDBP1 CD34 WNK1

3.44e-0444813M6509
CoexpressionGSE3982_EFF_MEMORY_CD4_TCELL_VS_TH1_UP

SETD2 QSER1 MYO16 LUZP1 DOP1A

3.76e-04198815M5577
CoexpressionGSE19941_IL10_KO_VS_IL10_KO_AND_NFKBP50_KO_LPS_AND_IL10_STIM_MACROPHAGE_UP

ATP7A UBR5 GLI3 TOX2 MYO16

3.85e-04199815M8115
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_UP

ABCA1 RESF1 MDM2 HSPA1A HSPA6

3.85e-04199815M7951
CoexpressionGSE41867_DAY15_EFFECTOR_VS_DAY30_MEMORY_CD8_TCELL_LCMV_ARMSTRONG_UP

STAM2 IL31RA MDM2 JMJD1C MYO16

3.85e-04199815M9523
CoexpressionGSE3982_MAC_VS_TH1_UP

EYA4 RADX CLOCK PLXNA1 PAPOLG

3.85e-04199815M5510
CoexpressionGSE8515_CTRL_VS_IL1_4H_STIM_MAC_UP

PTPN3 ATP7A LRRC37A2 WNK1 USH2A

3.85e-04199815M5759
CoexpressionGSE3994_WT_VS_PAC1_KO_ACTIVATED_MAST_CELL_DN

JAK3 CACNA2D4 ITSN2 LAMA1 TRRAP

3.94e-04200815M6372
CoexpressionGSE8921_UNSTIM_0H_VS_TLR1_2_STIM_MONOCYTE_24H_DN

CCNDBP1 RBM5 HSPA1B MEAK7 MAP3K1

3.94e-04200815M6411
CoexpressionGSE14308_TH1_VS_TH17_DN

SETD2 CCNDBP1 UBR5 RBM5 MEAK7

3.94e-04200815M3374
CoexpressionGSE22103_UNSTIM_VS_GMCSF_AND_IFNG_STIM_NEUTROPHIL_UP

PTPN3 DUSP6 RBM5 TRRAP MEAK7

3.94e-04200815M7789
CoexpressionGSE10240_CTRL_VS_IL22_STIM_PRIMARY_BRONCHIAL_EPITHELIAL_CELLS_UP

ABCA1 ATP7A CD34 CDK19 WNK1

3.94e-04200815M302
CoexpressionGSE41176_WT_VS_TAK1_KO_ANTI_IGM_STIM_BCELL_6H_UP

ZBTB44 EBF3 AHR NCKAP5 EWSR1

3.94e-04200815M9942
CoexpressionGSE39152_CD103_NEG_VS_POS_MEMORY_CD8_TCELL_DN

JAK3 ABCA1 ATP7A GLI3 AHR

3.94e-04200815M9074
CoexpressionGSE12392_WT_VS_IFNB_KO_CD8A_NEG_SPLEEN_DC_DN

JAK3 PTPN3 IL31RA WNK1 JMJD1C

3.94e-04200815M7150
CoexpressionGSE7460_FOXP3_MUT_VS_WT_ACT_WITH_TGFB_TCONV_UP

PTPN3 DSG2 UBR5 AHR HSPA1B

3.94e-04200815M5703
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

PTPN3 ATP7A RESF1 BRCA2 ADAMTS6 GLI3 CD34 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2 QSER1 HSPA1A HSPA8

6.71e-098317817gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_500

RESF1 DSG2 RADX GLI3 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2

5.45e-074367811gudmap_dev gonad_e11.5_F_GonMes_Sma_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#5

BRCA2 UBAP2L GLI3 DYRK1A EWSR1 QSER1 MDM2 WNK1 TFG LUZP1 EPHA5

1.81e-056297811Facebase_RNAseq_e10.5_Maxillary Arch_2500_K5
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

ATP7A GLI3 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2

2.24e-05418789gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_500

DSG2 RADX GLI3 DUSP6 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2

2.90e-05432789gudmap_dev gonad_e11.5_M_GonMes_Sma_500
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

ADAMTS6 GLI3 LAMA1 MUC16 ROBO2 ZDBF2 QSER1 HSPA1A

4.68e-05354788gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

SETD2 BRCA2 UBR5 STXBP5 GLI3 RBM5 ROBO2 NCKAP5 ZDBF2 LUZP1 EPHA5 PAPOLG

4.81e-058317812Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasdev gonad_e13.5_M_DevVasTestis_Flk_top-relative-expression-ranked_1000

JAK3 ABCA1 EBF3 CD34 DUSP6 ITSN2 LAMA1 AHR ROBO1 ROBO2 NCKAP5 HSPA1B

5.72e-058467812gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_1000
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000

ATP7A RESF1 DSG2 RADX GLI3 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2

5.92e-058497812gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_500

LAMA1 ROBO1 ROBO2 ZDBF2

6.15e-0558784gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_500
CoexpressionAtlasdev gonad_e11.5_F_GonMes_Sma_top-relative-expression-ranked_1000

PTPN3 RESF1 DSG2 RADX GLI3 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2

6.54e-058587812gudmap_dev gonad_e11.5_F_GonMes_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500

DSG2 GLI3 TP63 AHR ROBO1 ROBO2 TNRC6C EPHA5

9.21e-05390788gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#1_top-relative-expression-ranked_500

RADX GLI3 MUC16 ROBO2 ZDBF2

9.77e-05125785gudmap_dev gonad_e11.5_M_GonMes_Sma_k1_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

ABCA1 DSG2 GLI3 TP63 AHR ROBO1 ROBO2 TSHZ1 TNRC6C EPHA5 PAPOLG

1.11e-047697811gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500

ATP7A GLI3 LAMA1 MUC16 ROBO2 ZDBF2

1.14e-04207786gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

SETD2 BRCA2 ADAMTS6 STXBP5 ITSN2 RBM5 ROBO2 MDM2 HELQ LUZP1 PAPOLG

1.26e-047807811Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

ATP7A RADX GLI3 LAMA1 MUC16 ROBO2 ZDBF2

1.47e-04311787gudmap_dev gonad_e11.5_M_GonMes_Sma_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_1000

PTPN3 EYA4 DSG2 TP63 DUSP6 ROBO1 NCKAP5 SIX4 HSPA1A HSPA1B EPHA5

1.58e-048007811gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#1_top-relative-expression-ranked_500

DSG2 TP63 HSPA1A HSPA1B

1.68e-0475784gudmap_developingLowerUrinaryTract_P1_bladder_J_500_k1
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

ATP7A GLI3 CD34 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 TSHZ1 ZDBF2 HSPA8

2.10e-048277811gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_1000

EYA4 ROBO1 NCKAP5 SIX4 EPHA5

2.29e-04150785gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#3_top-relative-expression-ranked_1000

EYA4 EBF3 ROBO1 TNRC6C SIX4 EPHA5

2.73e-04243786gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000_k3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_200

ZBTB44 ATP7A RESF1 RBM5 ROBO2

2.75e-04156785gudmap_developingGonad_e12.5_ovary_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#1_top-relative-expression-ranked_200

EYA4 ROBO1 EPHA5

3.12e-0436783gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_200_k1
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

ABCA1 ATP7A BRCA2 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 ZDBF2 HSPA8

4.93e-047687810gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

ABCA1 ATP7A LAMA1 MUC16 ROBO2 NCKAP5 ZDBF2 HSPA1A HSPA1B HSPA8

5.18e-047737810gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

EYA4 RESF1 BRCA2 ADAMTS6 EBF3 UBAP2L GLI3 ATF1 QSER1 SIX4 TFG MEAK7 PHC1

5.99e-0412527813facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

ATP7A RADX GLI3 DUSP6 LAMA1 MUC16 ROBO1 ROBO2 ZDBF2 HSPA1B

6.32e-047937810gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#4_top-relative-expression-ranked_1000

DSG2 TP63 HSPA1A HSPA1B

6.76e-04108784gudmap_developingLowerUrinaryTract_P1_bladder_B_1000_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#1_top-relative-expression-ranked_500

DSG2 TP63 AHR

6.88e-0447783gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

BRCA2 UBR5 GLI3 ZDBF2 LUZP1

7.10e-04192785Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasgamma delta T cells, Tgd.vg5-.IEL, CD8a+ CD8b- TCRgd+ Vg5- CD44lo, Small Intestine, avg-3

JAK3 STXBP5 MAX AHR HSPA1A HSPA1B HSPA8

7.19e-04405787GSM605811_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#1_top-relative-expression-ranked_1000

EYA4 EBF3 ROBO1 SIX4 EPHA5

7.27e-04193785gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_1000_k1
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_500

ABCA1 EBF3 CD34 DUSP6 ITSN2 AHR HSPA8

7.62e-04409787gudmap_dev gonad_e11.5_F_ReproVasc_Flk_500
ToppCellCOVID-19-kidney-T-cells-2|kidney / Disease (COVID-19 only), tissue and cell type

JAK3 CEACAM21 HSPA1A HSPA1B HSPA6 HSPA8

1.35e-06191816698e6a28276704f8baa082d028db2345b973c4bc
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JAK3 HSPA1A HSPA1B HSPA6 HSPA8 LUZP1

1.39e-061928163f925a80b5e2b0577d573e88598a2984a5f6a789
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DUSP6 HSPA1A TOX2 HSPA1B HSPA6 HSPA8

1.66e-06198816294a48ef6c0b89c7be948452cea79d23d3901e75
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA1 PRDM10 SIX4 HELQ DOP1A

6.83e-06145815e808502fa52baf1c400f3c9b918a167127e78af9
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AHR HSPA1A TOX2 HSPA6 HSPA8

1.43e-05169815d4a0bd792bddfa34332d7dc432ce253f50d98c6f
ToppCellCOVID-19-kidney-Stressed_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

TSHZ1 HSPA1A HSPA1B JMJD1C HSPA6

1.89e-05179815754f69bac7a1d5137f5141f6193285ccbfe361cb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 DSG2 DUSP6 HSPA1A HSPA6

1.99e-05181815c2a8ee8679a1d71fcbff792cd516d3ce114f3ca6
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 ROBO1 USH2A MYO16 EPHA5

2.16e-051848152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 ROBO1 USH2A MYO16 EPHA5

2.16e-05184815ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA1 ROBO1 USH2A MYO16 EPHA5

2.16e-051848152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

EYA4 ADAMTS6 ROBO1 ROBO2 NCKAP5

2.21e-051858159f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell(00)_Basal-(4)_1wkpi|(00)_Basal / shred by cell type and Timepoint

TP63 DUSP6 AVPI1 HSPA1A HSPA1B

2.21e-05185815bf82ba905e5eee1c39a2731702071d3de10a78b8
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DUSP6 AHR MUC16 USH2A JMJD1C

2.27e-0518681523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

STAM2 PRDM10 RESF1 MAP3K1 LUZP1

2.27e-0518681503db813598b67b1e08f759758a1c2023396921fa
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

EYA4 EBF3 CD34 SIX4 CLOCK

2.27e-051868156259f0f2d5bc863782d09a901d6be2f387d1f074
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

AHR HSPA1A HSPA1B JMJD1C PAPOLG

2.33e-051878150099def970fbc828756fbf853eca2ce77b8cd342
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EYA4 ADAMTS6 ROBO1 ROBO2 NCKAP5

2.33e-0518781513731298bc562ec29582f5da1b4c97261284f6f1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CEACAM21 ROBO1 ROBO2 TOX2 MYO16

2.39e-05188815433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCellCOVID-19-kidney-T-cells-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

CEACAM21 HSPA1A HSPA1B HSPA6 HSPA8

2.39e-0518881515484c05cb496cd98ed3f79a6134c5cec8f09a4d
ToppCellLPS-IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS6 CD34 ROBO2 NCKAP5 TOX2

2.52e-05190815106ea0bb7b99c697ffc5443d72343df2484250c7
ToppCell390C-Myeloid-Mast_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

STXBP5 DUSP6 AHR HSPA1A HSPA1B

2.58e-0519181588bcd0b85b2112cef15c9e44d1429f9fba4a3400
ToppCell390C-Myeloid-Mast_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

STXBP5 DUSP6 AHR HSPA1A HSPA1B

2.58e-05191815c1517ea7b10a7f732725b4c0224fbfecae80d18b
ToppCell390C-Myeloid-Mast_cell|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

STXBP5 DUSP6 AHR HSPA1A HSPA1B

2.65e-05192815201d430af1e4fee7bc03baf0aca17db26f6f439a
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EYA4 EBF3 ROBO1 HSPA1A HSPA1B

2.65e-05192815d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell390C-Myeloid-Mast_cell-|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

STXBP5 DUSP6 AHR HSPA1A HSPA1B

2.65e-0519281515c1a0a0d07106118427135f166a1da710bf621a
ToppCelldroplet-Bladder-nan-3m-Epithelial-basal_bladder_epithelial_cell_(Krt5+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 TP63 DUSP6 AHR AVPI1

2.71e-05193815268925bfe85fb94a93a4ff8fe078d692df888140
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS6 CD34 ROBO2 NCKAP5 TOX2

2.78e-051948150b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellCOVID-19_Convalescent-PLT_4|COVID-19_Convalescent / Disease Group and Platelet Clusters

RESF1 AHR DCLRE1A TFG JMJD1C

2.78e-05194815ce1fad4e76a87f0c35e430ed1f2262395df882fd
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CD34 DUSP6 HSPA1A HSPA6 HSPA8

2.85e-051958155a8b26f443684f9f194cc85a4a390144b7242403
ToppCell10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITSN2 SIX4 WNK1 HSPA1A HSPA8

2.92e-05196815ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCellIPF-Endothelial-VE_Capillary_B|Endothelial / Disease state, Lineage and Cell class

ADAMTS6 NCKAP5 HSPA1A TOX2 HSPA1B

2.92e-051968158f0f72ead06abe02b575e443552eacc2151077ef
ToppCellmLN-T_cell-Treg|T_cell / Region, Cell class and subclass

AHR HSPA1A TOX2 HSPA1B MAP3K1

2.99e-051978153779489d57ebda33277c79cba037f4c73128c8ba
ToppCellBronchial_Biopsy-Epithelial-Basal_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DSG2 TP63 DUSP6 NCKAP5 AVPI1

2.99e-05197815a4855c5aebea4f0fed4eb035844572e82e5bac46
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ABCA1 CLLU1-AS1 AVPI1 HSPA1A HSPA6

2.99e-051978156c42ce26574adcc6dfc5dd8109c9943fe5cf12d5
ToppCell343B-Lymphocytic-NK_cells-NK_cell_A|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

HSPA1A TOX2 HSPA1B HSPA6 HSPA8

2.99e-05197815cd54e6ad175529327fa0372033016b3b978dd452
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EYA4 ADAMTS6 HSPA1A HSPA6 HSPA8

2.99e-051978152a90422ba400b951517603a916f34221056d0f3d
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CD34 DUSP6 NCKAP5 HSPA1A HSPA1B

2.99e-05197815b2b7f8dc8ca421441e4c99c4f5d18fbc1668d79f
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PTPN3 EYA4 GLI3 TP63 AVPI1

2.99e-051978151e915957ea6a4550ecb9d6ee4b232aa5800faf20
ToppCellnormal_Lung-Myeloid_cells-mo-Mac|Myeloid_cells / Location, Cell class and cell subclass

ABCA1 AHR NCKAP5 HSPA1A HSPA1B

3.07e-05198815fbd72ebaba73cc30e79dc8a8c3d46b6f863c1494
ToppCellBasal-basal-7|World / Class top

TP63 DUSP6 AVPI1 HSPA1A HSPA8

3.07e-05198815240fe56b41b9435e62c66ac7161ef51f89e73e44
ToppCellCaecum-T_cell-Th1|T_cell / Region, Cell class and subclass

PTPN3 HSPA1A HSPA1B HSPA6 HSPA8

3.14e-0519981513a80e6d3cf9c831edbe0644545071153e35f82b
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early|World / Primary Cells by Cluster

ADAMTS6 GLI3 HSPA1A HSPA1B HSPA6

3.14e-05199815549391e7a4285da1c0e366654530bcf1cd33fbae
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

EYA4 GLI3 TP63 NCKAP5 AVPI1

3.14e-0519981594a7867e800df352731796de8c24cba133c29622
ToppCellNon-neuronal-Non-dividing-Radial_Glia-early-40|World / Primary Cells by Cluster

ADAMTS6 GLI3 HSPA1A HSPA1B HSPA6

3.14e-0519981523625d757173bdd35a51c7919ff4b588168d2553
ToppCellCOVID-19-COVID-19_Mild-Myeloid-immature_Neutrophil|COVID-19_Mild / Disease, condition lineage and cell class

SLC26A8 STXBP5 TP63 HSPA1A MYO16

3.14e-05199815e222b90caf45904d8f763574e7b6aac13333df92
ToppCellSigmoid-T_cell-Th1|T_cell / Region, Cell class and subclass

PTPN3 HSPA1A HSPA1B HSPA6 HSPA8

3.22e-05200815bc9433a8ec3a6f10816730a32b821c63d78e6e87
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-05200815bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellControl_saline-Endothelial-Endothelial-Alv_Gen_Intermediate|Control_saline / Treatment groups by lineage, cell group, cell type

CD34 AHR NCKAP5 HSPA1B LUZP1

3.22e-05200815041a34080120c9f613373c20dcc366292f558040
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-0520081589821a264e872ed53e08e9d3609d5cc5c314503e
ToppCellLPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-0520081579e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-0520081566f7e8ee63c828f17468e79a4b816346b33e8980
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-05200815b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-05200815a1fa6bae5a688faf488d6925cd3fad725dfa916b
ToppCellLPS_IL1RA_TNF-Endothelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-05200815d01cec331be3b03cef80e9536fc531285bcf00f6
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

CACNA2D4 EYA4 EBF3 JMJD1C LUZP1

3.22e-052008157c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellLPS_only-Endothelial-Endothelial-Alv_Cap|LPS_only / Treatment groups by lineage, cell group, cell type

RESF1 CD34 AHR TOX2 LUZP1

3.22e-05200815432384faeade8e609154fab3d96c955a8ec868dd
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PTPN3 TP63 MUC16 HSPA1A HSPA1B

3.22e-05200815ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellVE-CD8-exh_CD4|VE / Condition, Cell_class and T cell subcluster

PTPN3 RESF1 TP63 MUC16

1.05e-041348144413fec495907184b6d5cf4bda39359506b2c172
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DUSP6 HSPA1B HSPA6

1.10e-0451813d43b0813f7c456f8fff77197fbbaef2f4d160563
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

EYA4 EBF3 MUC16 HSPA6

1.54e-04148814c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 ATP7A MAP10 HELQ

1.83e-04155814441fcb6d05364fc6f4973f0b973f1a80b573ce1f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

NPAP1 ROBO2 PLXNA1 EPHA5

1.88e-041568147e6805ebc7bc2f9c5965321d16922c155719970f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-IPC_like-IPs_and_early_cortical_neurons|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

NPAP1 ROBO2 PLXNA1 EPHA5

1.88e-04156814741de05295b2d012ac8576378f37709a97c8fb50
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ROBO2 USH2A MYO16 EPHA5

2.02e-041598145335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR+_ILC3|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

USP28 AHR CLOCK TOX2

2.12e-04161814d59713ca84aa2acadfc9b3150d5f525e1b288860
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 CD34 ROBO1 ROBO2

2.12e-041618141b805f77790aeb8a71b08bfac2fe2eed7343258f
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD4-Trm_Th1/Th17|bone_marrow / Manually curated celltypes from each tissue

RESF1 HSPA1A HSPA6 HSPA8

2.22e-041638144d1fd0b1246833723b938eca0cb246e937380e12
ToppCell10x3'2.3-week_14-16-Lymphocytic_NK-T_NK-NK_progenitor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

AHR ZDBF2 MAP10 TOX2

2.38e-04166814b041010038a570ad929812f35514cb54e4f68f66
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

EYA4 OTUD7A ROBO1 ROBO2

2.38e-0416681494636dbc039f794c735960c3425e00bdd5523602
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

ABCA1 DUSP6 AHR HSPA1B

2.49e-04168814bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

ABCA1 EYA4 NCKAP5 MYO16

2.61e-04170814e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell10x5'-Lung-Lymphocytic_T_CD8-Trm_gut_CD8|Lung / Manually curated celltypes from each tissue

RESF1 HSPA1A HSPA6 HSPA8

2.67e-04171814c8ccb7795ce8321739e3bc07db2ffc183d04e660
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA1 HSPA1A JMJD1C HSPA6

2.67e-041718145e93c76ee60f9d0590ebb140812653a5e1369417
ToppCellControl-CD4+_T_activated|World / Disease group and Cell class

AVPI1 HSPA1A HSPA1B HSPA6

2.79e-0417381412f8e4276b290bb388a56de4c8d8dd60415b2f63
ToppCell367C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS6 HSPA1A HSPA1B HSPA6

2.79e-041738145d3c917e4d0de3158550a8ab2006ddfa87159ffa
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS6 CD34 TOX2 LUZP1

2.85e-041748143d4c05ea5719ca65e85d1f15198453034791087c
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-5|TCGA-Pancreas / Sample_Type by Project: Shred V9

MUC16 SIX4 MEAK7 PLXNA1

2.85e-0417481473e1ad4007d94fca25ed7c6fbe5d205d4e1b8a3b
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

ABCA1 EYA4 NCKAP5 MYO16

2.85e-04174814548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellAT1-AT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

EYA4 IL31RA TP63 NCKAP5

2.98e-04176814f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCellNS-moderate-d_0-4-Myeloid-pDC|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

JAK3 LRRC37A BRCA2 RADX

3.04e-04177814de1ffe3df76100d46ca158bdd2fea2ebbd4656b4
ToppCellAdult-Immune-enucleated_erythrocyte-D231|Adult / Lineage, Cell type, age group and donor

MUC16 HSPA1A HSPA1B HSPA6

3.04e-0417781415ee303fb6caea1fd645c3b777666196ce500a1c
ToppCellSevere-CD4+_T_activated|Severe / Disease group and Cell class

HSPA1A HSPA1B HSPA6 HSPA8

3.04e-04177814a08f170f1143fcdd7d0842a54d9b807a4548f8b7
ToppCellAdult-Endothelial-endothelial_cell_of_bronchial_vessel-D175|Adult / Lineage, Cell type, age group and donor

EBF3 CD34 TSHZ1 LUZP1

3.04e-04177814c9f269765c7d5d29caab75910e51645606ed562e
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c05-FOS|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ1 HSPA1A HSPA1B HSPA8

3.04e-041778143d1b142aa2bd18df14816abaca356596b297394e
ToppCellSevere-CD4+_T_activated|World / Disease group and Cell class

HSPA1A HSPA1B HSPA6 HSPA8

3.11e-04178814ef6111238703579a34bd6948bd9d4ca6b7e16063
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.0.3|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RADX HSPA1A HSPA6 HSPA8

3.17e-041798149af894dfbe44e9706f5d178769ceda3b4e2d89c0
ToppCell5'-Adult-SmallIntestine-Hematopoietic-T_cells-Activated_CD4_T|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAK3 HSPA1A HSPA6 HSPA8

3.17e-0417981402218c048e4dec0c0a3d63d2abb4feb4c3e82697
ToppCellP15-Endothelial-capillary_endothelial_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD34 AHR HSPA8 LUZP1

3.24e-0418081463e7ec20a93452a02bf904acebdbe3d0d9ae8894
ToppCellChildren_(3_yrs)-Mesenchymal-myofibroblast_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

EYA4 GLI3 ROBO1 ROBO2

3.24e-0418081401f2e5d96016823482f89ba503d007d4bd88eeac
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-Treg|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JAK3 RESF1 WNK1 TOX2

3.31e-04181814a6c8b33a392de3df2f179317e329e45d3d8c6f52
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK19 AVPI1 TOX2 LUZP1

3.31e-041818144d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EYA4 ADAMTS6 ROBO1 ROBO2

3.31e-04181814d7e04e0ca549eac6d9b1192b6578f9b54943d54f
ToppCellCOVID-19-kidney-Mito-rich_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

JAK3 HSPA1A HSPA1B HSPA6

3.31e-041818148448c2ad560cfd48bfe9dc1dd3a64373e6a622dd
ToppCellE18.5-samps-Mesenchymal-Myofibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

ADAMTS6 ROBO1 ROBO2 TSHZ1

3.45e-04183814de08f9ea02b7244d5a8788064631d10f06565337
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK19 AVPI1 TOX2 LUZP1

3.45e-041838143427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS6 USP28 HSPA1A HSPA6

3.45e-04183814983ca1342ddd365e1f1df32a456394b002b10e41
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRDM10 CD34 AHR TOX2

3.45e-04183814f142b320023eef00b48d4820c46214c9794d37e7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EYA4 STXBP5 NPAP1 ROBO2

3.45e-04183814b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellP15-Endothelial|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD34 AHR HSPA8 LUZP1

3.45e-04183814ef82ce4658a775ee2ef0e564d2d1042898a1bd75
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD8-CD8_TRM|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

JAK3 LRRC37A RESF1 HSPA1B

3.52e-0418481417ffa0e890960c00a3b5fa33d48caba66c61dbb0
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HSPA1A HSPA1B HSPA6 HSPA8

9.51e-0550524GAVISH_3CA_METAPROGRAM_B_CELLS_HSP_STRESS
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

HSPA1A HSPA1B HSPA6 HSPA8

9.51e-0550524GAVISH_3CA_METAPROGRAM_MACROPHAGES_STRESS_HSP
DrugPlant Oils

ABCA1 RESF1 DUSP6 AHR EWSR1 QSER1 HSPA1A TOX2 JMJD1C HSPA6 HSPA8

1.44e-064968111ctd:D010938
DrugMagnetite Nanoparticles

EYA4 ATP7A BRCA2 DSG2 UBAP2L STXBP5 GLI3 DUSP6 ITSN2 RBM5 QSER1 MDM2 HSPA1A TOX2 HSPA1B JMJD1C HSPA8

2.88e-0613108117ctd:D058185
DrugSC-58125; Up 200; 10uM; SKMEL5; HG-U133A

ADAMTS6 TP63 CD34 CDK19 NPAP1 RBM5 LUZP1

7.06e-06199817507_UP
Diseasegraft-versus-host disease (biomarker_via_orthology)

HSPA1A HSPA1B HSPA8

1.98e-075813DOID:0081267 (biomarker_via_orthology)
DiseaseProstatic Neoplasms

SETD2 BRCA2 USP28 ITSN2 AHR ROBO1 ROBO2 EWSR1 MDM2 HSPA1A MAP3K1

9.70e-076168111C0033578
DiseaseMalignant neoplasm of prostate

SETD2 BRCA2 USP28 ITSN2 AHR ROBO1 ROBO2 EWSR1 MDM2 HSPA1A MAP3K1

9.70e-076168111C0376358
DiseaseMalignant neoplasm of breast

SETD2 LRRC37A BRCA2 ITSN2 LRRC37A2 AHR ROBO1 SIX4 MDM2 WNK1 HELQ HSPA1B MAP3K1 DOP1A

1.24e-0610748114C0006142
DiseaseMammary Carcinoma, Human

SETD2 LRRC37A BRCA2 ITSN2 LRRC37A2 AHR MDM2 HSPA1B MAP3K1

1.40e-05525819C4704874
DiseaseMammary Neoplasms, Human

SETD2 LRRC37A BRCA2 ITSN2 LRRC37A2 AHR MDM2 HSPA1B MAP3K1

1.40e-05525819C1257931
DiseaseMammary Neoplasms

SETD2 LRRC37A BRCA2 ITSN2 LRRC37A2 AHR MDM2 HSPA1B MAP3K1

1.44e-05527819C1458155
DiseaseBreast Carcinoma

SETD2 LRRC37A BRCA2 ITSN2 LRRC37A2 AHR MDM2 HSPA1B MAP3K1

1.70e-05538819C0678222
DiseaseMalignant Squamous Cell Neoplasm

BRCA2 TP63

2.23e-053812C0751688
DiseaseSquamous Cell Neoplasms

BRCA2 TP63

2.23e-053812C0206720
DiseaseClear Cell Sarcoma of Soft Tissue

EWSR1 ATF1

4.45e-054812C0206651
Diseasecortical thickness

EYA4 GLI3 LAMA1 ROBO1 ROBO2 NCKAP5 QSER1 CLOCK JMJD1C MYO16 MAP3K1 LUZP1

5.01e-0511138112EFO_0004840
Diseaseupper aerodigestive tract neoplasm

BRCA2 DCLRE1A NCKAP5 WNK1 HELQ MEAK7

6.08e-05246816EFO_0004284
DiseaseExtraskeletal Myxoid Chondrosarcoma

EWSR1 TFG

7.40e-055812C1275278
Diseasecutaneous squamous cell carcinoma

BRCA2 TP63 AHR

1.02e-0433813EFO_1001927
Diseasebrain connectivity measurement

GLI3 LRRC37A2 ROBO2 NCKAP5 TSHZ1 ATF1 MYO16

1.17e-04400817EFO_0005210
DiseaseSchizophrenia

CBLIF SLC26A8 ABCA1 CEACAM21 LAMA1 TRRAP CLOCK HSPA1A HSPA1B MYO16

1.51e-048838110C0036341
Diseasemyoclonic-atonic epilepsy (implicated_via_orthology)

ROBO1 ROBO2

1.55e-047812DOID:0060475 (implicated_via_orthology)
Diseasebranchiootorenal syndrome (implicated_via_orthology)

EYA4 SIX4

1.55e-047812DOID:14702 (implicated_via_orthology)
DiseaseDental enamel hypoplasia, dental caries, tooth agenesis

ROBO1 PAPOLG

1.55e-047812EFO_0003819, EFO_0005410, EFO_1001304
Diseaseneuroimaging measurement

GLI3 TP63 ROBO1 ROBO2 NCKAP5 QSER1 MEAK7 JMJD1C MYO16 MAP3K1 LUZP1

1.60e-0410698111EFO_0004346
Diseaseeosinophil percentage of leukocytes

SETD2 RESF1 MAX DYRK1A AHR WNK1 TOX2 JMJD1C PHC1

2.07e-04746819EFO_0007991
Diseasemean corpuscular hemoglobin concentration

SLC26A8 UBR5 UBAP2L PCDHGA5 MAX LRRC37A2 MDM2 TOX2 MEAK7 HSPA8 MYO16

2.13e-0411058111EFO_0004528
DiseaseMajor depression, single episode

HSPA1A HSPA1B

2.65e-049812C0024517
Diseasereaction time measurement

SETD2 CACNA2D4 CDK19 ITSN2 LRRC37A2 NCKAP5 TSHZ1 TNRC6C

4.51e-04658818EFO_0008393
DiseaseAlzheimer's disease (is_implicated_in)

ABCA1 CLOCK HSPA1A HSPA1B

4.88e-04132814DOID:10652 (is_implicated_in)
Diseasewaist-hip ratio

ABCA1 EYA4 ADAMTS6 GLI3 CD34 DUSP6 ROBO1 WNK1 CLOCK JMJD1C PHC1

5.13e-0412268111EFO_0004343
DiseaseAtherosclerosis

ABCA1 AHR HSPA1B

5.80e-0459813C0004153
DiseaseAtherogenesis

ABCA1 AHR HSPA1B

5.80e-0459813C1563937
Diseasemelanoma

BRCA2 NPAP1 MDM2 TRRAP HSPA1A

6.14e-04248815C0025202
Diseaseresponse to opioid

CACNA2D4 TP63 MUC16

6.39e-0461813EFO_0008541
DiseaseColorectal Carcinoma

ABCA1 EYA4 GLI3 TP63 LAMA1 NPAP1 WNK1 TFG

6.89e-04702818C0009402
DiseaseDown syndrome (implicated_via_orthology)

DYRK1A DOP1A

7.64e-0415812DOID:14250 (implicated_via_orthology)
Diseasesquamous cell carcinoma

BRCA2 TP63 AHR

8.41e-0467813EFO_0000707
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ROBO1 ROBO2 WNK1 HSPA8

9.34e-04157814DOID:224 (biomarker_via_orthology)
Diseasenon-small cell lung carcinoma

BRCA2 TP63 LAMA1

1.17e-0375813EFO_0003060
DiseaseInguinal hernia

ADAMTS6 ROBO1 QSER1 HSPA1A HSPA1B

1.18e-03287815HP_0000023
Diseasealpha-tocopherol measurement

DYRK1A USH2A

1.37e-0320812EFO_0007898
DiseaseCarcinoma of lung

BRCA2 TP63

1.81e-0323812C0684249
DiseaseCarcinoma, Pancreatic Ductal

HSPA1A HSPA1B

1.98e-0324812C0887833
Diseasecomplement C4b measurement

HSPA1A HSPA1B

2.14e-0325812EFO_0008092
DiseaseDNA methylation

ABCA1 PRDM10 RESF1 ADAMTS6 GLI3 AHR USH2A

2.18e-03656817GO_0006306
DiseaseCholangiocarcinoma

PTPN3 ROBO2

2.32e-0326812C0206698
Diseasediabetes mellitus (implicated_via_orthology)

MAX CLOCK

2.32e-0326812DOID:9351 (implicated_via_orthology)
Diseaseresponse to norepinephrine-dopamine reuptake inhibitor

ZBTB44 ROBO2

2.32e-0326812EFO_0007870
DiseaseAdenocarcinoma of large intestine

UBR5 MDM2 TRRAP

2.37e-0396813C1319315
DiseaseAdenocarcinoma of lung (disorder)

TP63 AHR WNK1 EPHA5

2.52e-03206814C0152013
DiseaseAlzheimer disease, age at onset

EYA4 ITSN2 LAMA1 USH2A MYO16

2.57e-03343815EFO_0004847, MONDO_0004975
DiseasePancreatic Neoplasm

BRCA2 TP63 AHR

2.66e-03100813C0030297
Diseaseblood cobalt measurement

MUC16 ROBO2 USH2A

2.74e-03101813EFO_0007577

Protein segments in the cluster

PeptideGeneStartEntry
YPAELNNINNTQTTT

AHR

811

P35869
QPTDVSYTQAQTTAT

EWSR1

46

Q01844
NYQSSVQGSSQSQST

CDK19

466

Q9BWU1
QSQSTLGYSSSSQQS

CDK19

476

Q9BWU1
YESVAQPSIQASSTT

CEACAM21

141

Q3KPI0
QYVSVNVTTNQAAPS

EPHA5

456

P54756
VNSSSSSTQIYQAVS

ABCA1

291

O95477
NPQSATETASSEQYL

AVPI1

106

Q5T686
NAISTTSVNNAYTPQ

DOP1A

1401

Q5JWR5
RVYNSPTNSSSTQDS

DYRK1A

631

Q13627
LNDTSTVSYSLPINN

ADAMTS6

221

Q9UKP5
SQQRSPSYTNDSTAT

ATP7A

266

Q04656
SSQTVTPENQTLNYS

QSER1

381

Q2KHR3
SQGLSPVSQTQVSYS

QSER1

431

Q2KHR3
PVSQTQVSYSSQSQV

QSER1

436

Q2KHR3
NQPASVTDYQNVSFS

ITSN2

851

Q9NZM3
TSSLVQPQSQYQLSQ

JAK3

496

P52333
NFPQASYSTSVTENN

PCDHGA5

451

Q9Y5G8
SENNPAQSYLTQKSS

PTPN3

441

P26045
PVNSQYFQTTSTNLS

RADX

606

Q6NSI4
TLQSSYQIPTENSMT

DSG2

1056

Q14126
SVQTQSTPYVNSVAV

MUC16

1996

Q8WXI7
STPQSQKQTLQNEYS

LRRC37A3

171

O60309
QKQTLQNEYSSTDTP

LRRC37A3

176

O60309
SSCSSQQSPISNYSN

GLI3

711

P10071
EKSQSPQTSQVSSYL

MAP10

841

Q9P2G4
RSSAQLQTNYPSSDN

MAX

106

P61244
STPQSQKQTLQNEYS

LRRC37A2

171

A6NM11
QKQTLQNEYSSTDTP

LRRC37A2

176

A6NM11
STPQSQKQTLQNEYS

LRRC37A

171

A6NMS7
QKQTLQNEYSSTDTP

LRRC37A

176

A6NMS7
YPESNTNLTETMNTT

IL31RA

271

Q8NI17
QSLLESSNTNAVYSP

MYO16

871

Q9Y6X6
QSLPQSNYFTTLSNS

JMJD1C

1086

Q15652
SYDSNSLTVSLNNPS

FSIP2

3906

Q5CZC0
PTKQTQIFTTYSDNQ

HSPA1B

421

P0DMV9
VPKQTSAYNISNSST

PLXNA1

1601

Q9UIW2
TYPQQNRSLSSQSYS

OTUD7A

796

Q8TE49
SQQQTTQYIITTTTN

PRDM10

1121

Q9NQV6
TCTTYNSPQLSAQEN

MEAK7

386

Q6P9B6
AAVVSQSPQLYNQTS

RBM5

406

P52756
QQNSTYNVSTSTRTV

PAPOLG

321

Q9BWT3
DQQIQNGSSSTSPYN

TP63

121

Q9H3D4
APSSTIYANNSVSNS

EYA4

246

O95677
PTSASNITVIYTINN

CBLIF

306

P27352
TNQSPYSVIENSALA

BRCA2

1656

P51587
TQSPENNDLISYNSV

CCNDBP1

141

O95273
NTSISSVQLPTNVYN

CACNA2D4

201

Q7Z3S7
NENYSLSNRQVSSPS

LUZP1

411

Q86V48
SQVEGYLSSQPTQNT

DCLRE1A

471

Q6PJP8
QTQTFTTYSDNQPGV

HSPA6

426

P17066
PTKQTQIFTTYSDNQ

HSPA1A

421

P0DMV8
PSSQAIYFENLQNSS

HELQ

196

Q8TDG4
STPQQSNYNTVSTSM

EBF3

476

Q9H4W6
TPSNQNVYQVDSLQS

DUSP6

366

Q16828
NVSTNVSYQETTTPS

CD34

51

P28906
SVYGNTNSSVQSQTS

CD34

101

P28906
PTKQTQTFTTYSDNQ

HSPA8

421

P11142
QASVPNNYLETTENS

MAP3K1

886

Q13233
IPSQNQTSLTYSQGS

USH2A

5126

O75445
EPQTSTSQNVSFSAQ

TNRC6C

161

Q9HCJ0
TESFSSRTVTQNPQQ

NCKAP5

756

O14513
TSAVPSQQYATQTDK

RESF1

261

Q9HCM1
NTSQTASEDQVPYTV

SLC26A8

651

Q96RN1
QPQISSTNYNTLTLN

LAMA1

2131

P25391
SQSQESEDYSQPSTS

MDM2

386

Q00987
STVTSVSNTNYATLQ

SIX4

651

Q9UIU6
VSPSSSQEISENQYA

STXBP5

901

Q5T5C0
QTTDSLPLTTYTSQV

NPAP1

406

Q9NZP6
STQQGTTILQYAQTS

ATF1

141

P18846
TAYPTFATQQQQSQT

CLOCK

736

O15516
QTVQPSISQTCTSYG

CLLU1-AS1

21

Q5K130
IQSTTYTSQNNAQGP

UBAP2L

576

Q14157
AQTYTAQTSQPTNYT

TFG

326

Q92734
QTSSPQVLNSSASYS

ZBTB44

201

Q8NCP5
SPQSTSDYPQQSVTE

ZDBF2

501

Q9HCK1
NSSVTAQPAQTSYLS

STAM2

436

O75886
SNLQSATGTTAYTQQ

STAM2

466

O75886
DMSSYQNTTSNLPQL

STAM2

486

O75886
PSQTLISSATYTQIQ

PHC1

361

P78364
NSSSQITQATPYATT

ROBO2

986

Q9HCK4
TPYATTQLIQSNLSN

ROBO1

1071

Q9Y6N7
NSSSQDYSTSQEPSV

USP28

711

Q96RU2
SVQQQYSPAQSQATI

SETD2

2281

Q9BYW2
PEYINSAVSSQTLSQ

nan

86

Q8N9P0
NPELLSTSQTYNGQS

TOX2

56

Q96NM4
PQQTVQYSLSQTSTS

WNK1

751

Q9H4A3
SENFENVTSSPQYST

TRRAP

46

Q9Y4A5
AQSYQNSPVSSATNQ

TSHZ1

56

Q6ZSZ6
SYSVSSNSLPINVQV

ZP4

286

Q12836
SSQSQSSYIIRNPQQ

UBR5

1531

O95071